104460-70-0 | 4-Bromo-2-fluoro-5-(trifluoromethyl)aniline

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$15.00	$10.00
1g	97%	in stock	$18.00	$12.00
5g	97%	in stock	$25.00	$18.00
10g	97%	in stock	$35.00	$25.00

Description

• Catalog Number: AB66861
• Chemical Name: 4-Bromo-2-fluoro-5-(trifluoromethyl)aniline
• CAS Number: 104460-70-0
• Molecular Formula: C7H4BrF4N
• Molecular Weight: 258.011
• MDL Number: MFCD04973757
• SMILES: Fc1cc(Br)c(cc1N)C(F)(F)F

Computed Properties

• Complexity: 184
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 1
• XLogP3: 3.3

Upstream Synthesis Route

4-Bromo-2-fluoro-5-(trifluoromethyl)aniline is a versatile chemical compound widely employed in chemical synthesis due to its unique properties and reactivity. This compound serves as a valuable building block in the production of various pharmaceuticals, agrochemicals, and advanced materials.In chemical synthesis, 4-Bromo-2-fluoro-5-(trifluoromethyl)aniline is utilized as a key intermediate in the preparation of complex molecular structures. Its strategic positioning of functional groups enables efficient diversification through a variety of synthetic routes. This compound can undergo various transformations, including nucleophilic substitution, aromatic substitution, and transition metal-catalyzed coupling reactions, to introduce additional functionalities or construct intricate molecular frameworks.Moreover, the trifluoromethyl group present in 4-Bromo-2-fluoro-5-(trifluoromethyl)aniline contributes to the compound's enhanced chemical stability, lipophilicity, and bioavailability, making it an attractive candidate for medicinal chemistry applications. By incorporating this moiety into drug molecules, researchers can modulate properties such as metabolic stability, protein binding affinity, and membrane permeability, thereby improving the pharmacokinetic profile and therapeutic efficacy of the resulting compounds.Overall, the strategic placement of bromine, fluorine, and trifluoromethyl substituents in 4-Bromo-2-fluoro-5-(trifluoromethyl)aniline offers a valuable platform for molecular manipulation in chemical synthesis, enabling the efficient construction of diverse chemical entities with tailored properties and functionalities.