1045792-66-2 | CAY10603

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$26.00	$18.00
5mg	98%	in stock	$57.00	$40.00
10mg	98%	in stock	$90.00	$63.00
50mg	98%	in stock	$287.00	$201.00
100mg	98%	in stock	$489.00	$342.00
250mg	98%	in stock	$927.00	$649.00

Description

• Catalog Number: AD70132
• Chemical Name: CAY10603
• CAS Number: 1045792-66-2
• Molecular Formula: C22H30N4O6
• Molecular Weight: 446.4968
• MDL Number: MFCD17010286
• SMILES: ONC(=O)CCCCCCNC(=O)c1noc(c1)c1ccc(cc1)NC(=O)OC(C)(C)C

Computed Properties

• Complexity: 616
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 12
• XLogP3: 2.6

Upstream Synthesis Route

Carbamic acid, N-[4-[3-[[[7-(hydroxyamino)-7-oxoheptyl]amino]carbonyl]-5-isoxazolyl]phenyl]-, 1,1-dimethylethyl ester is a versatile compound used in chemical synthesis for the preparation of various pharmaceuticals, agrochemicals, and specialty chemicals. It serves as a key intermediate in the synthesis of complex molecules due to its unique structure and reactivity. This compound plays a crucial role in the creation of novel chemical entities with potential therapeutic applications. Its usage in chemical synthesis enables the development of new materials and compounds that have diverse industrial and research applications.

Literature

• An HDAC6 Inhibitor Confers Protection and Selectively Inhibits B-Cell Infiltration in DSS-Induced Colitis in Mice.

  The Journal of pharmacology and experimental therapeutics 20170101

• Development and therapeutic implications of selective histone deacetylase 6 inhibitors.

  Journal of medicinal chemistry 20130822

• Identification of potent Yes1 kinase inhibitors using a library screening approach.

  Bioorganic & medicinal chemistry letters 20130801

• Inhibitors selective for HDAC6 in enzymes and cells.

  Bioorganic & medicinal chemistry letters 20101201

• Use of the nitrile oxide cycloaddition (NOC) reaction for molecular probe generation: a new class of enzyme selective histone deacetylase inhibitors (HDACIs) showing picomolar activity at HDAC6.

  Journal of medicinal chemistry 20080814