104632-26-0 | (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$15.00	$10.00
5g	97%	in stock	$42.00	$29.00
25g	97%	in stock	$186.00	$130.00

Description

• Catalog Number: AB56175
• Chemical Name: (6S)-6-N-propyl-4,5,6,7-tetrahydro-1,3-benzothiazole-2,6-diamine
• CAS Number: 104632-26-0
• Molecular Formula: C10H17N3S
• Molecular Weight: 211.3271
• MDL Number: MFCD00869076
• SMILES: CCCN[C@H]1CCc2c(C1)sc(n2)N

Computed Properties

• Complexity: 188
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: 1.9

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• Liposomes for Targeted Delivery of Active Agents against Neurodegenerative Diseases (Alzheimer's Disease and Parkinson's Disease).

  Journal of drug delivery 20110101

• Pregnancy in multiple system atrophy: a case report.

  Journal of medical case reports 20110101

• Pramipexole-induced peripheral edema in a patient with bipolar depression.

  The Journal of neuropsychiatry and clinical neurosciences 20110101

• A role for locus coeruleus in Parkinson tremor.

  Frontiers in human neuroscience 20110101

• Proton magnetic resonance spectroscopy in depression.

  Indian journal of psychiatry 20110101

• Periodic Limbic Movement Disorder during Sleep as Diabetes-Related Syndrome? A Polysomnographic Study.

  ISRN endocrinology 20110101

• Apathy and anhedonia in Parkinson's disease.

  ISRN neurology 20110101

• Exercise dependence induced by pramipexole in Parkinson's Disease-a case report.

  Movement disorders : official journal of the Movement Disorder Society 20101215

• Stability studies and structural characterization of pramipexole.

  Journal of pharmaceutical and biomedical analysis 20101201

• Levodopa and pramipexole effects on presynaptic dopamine PET markers and estimated dopamine release.

  European journal of nuclear medicine and molecular imaging 20101201

• Pramipexole for stage 2 treatment-resistant major depression: an open study.

  Progress in neuro-psychopharmacology & biological psychiatry 20101201

• Dopamine agonists and Othello's syndrome.

  Parkinsonism & related disorders 20101201

• Dexpramipexole, the R(+) enantiomer of pramipexole, for the potential treatment of amyotrophic lateral sclerosis.

  IDrugs : the investigational drugs journal 20101201

• Seniors with Parkinson's disease: initial medical treatment.

  Journal of clinical neurology (Seoul, Korea) 20101201

• Successful drug development despite adverse preclinical findings part 2: examples.

  Journal of toxicologic pathology 20101201

• Clinical and molecular characterisation of hereditary dopamine transporter deficiency syndrome: an observational cohort and experimental study.

  The Lancet. Neurology 20101126

• Randomized, double-blind, multicenter evaluation of pramipexole extended release once daily in early Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20101115

• From the cell to the clinic: a comparative review of the partial D₂/D₃receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease.

  Pharmacology & therapeutics 20101101

• Dopamine receptor agonists for the treatment of early or advanced Parkinson's disease.

  CNS drugs 20101101

• Validated ultra-performance liquid chromatography tandem mass spectrometry method for the determination of pramipexole in human plasma.

  Journal of chromatographic science 20101101

• The role of pramipexole in a severe Parkinson's disease model in mice.

  Therapeutic advances in neurological disorders 20101101

• Efficacy, safety, and tolerability of overnight switching from immediate- to once daily extended-release pramipexole in early Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20101030

• Toxicity assessment of pramipexole in juvenile rhesus monkeys.

  Toxicology 20101029

• Neuroprotection of pramipexole in UPS impairment induced animal model of Parkinson's disease.

  Neurochemical research 20101001

• Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation.

  Psychopharmacology 20101001

• Role of pramipexole in the management of Parkinson's disease.

  CNS drugs 20101001

• Hypotension and bradycardia associated with concomitant tizanidine and lisinopril therapy.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101001

• Differential pharmacological responses of catatonia-like signs in frontotemporal dementia.

  Neurocase 20101001

• [Dopaminergic neuroprotection and reconstruction of neural network tiara].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101001

• Clozapine for medication-related pathological gambling in Parkinson disease.

  Movement disorders : official journal of the Movement Disorder Society 20100915

• Adverse drug reactions to dopamine agonists: a comparative study in the French Pharmacovigilance Database.

  Movement disorders : official journal of the Movement Disorder Society 20100915

• Long-term use of pramipexole in bipolar depression: a naturalistic retrospective chart review.

  The Psychiatric quarterly 20100901

• Isolated delusional syndrome in Parkinson's Disease.

  Parkinsonism & related disorders 20100901

• An interaction between levodopa and enteral nutrition resulting in neuroleptic malignant-like syndrome and prolonged ICU stay.

  The Annals of pharmacotherapy 20100901

• Pramipexole extended-release (once-daily formulation) for the treatment of Parkinson's disease.

  Expert opinion on pharmacotherapy 20100901

• Recurrence of cluster headache with pramipexole.

  Acta neurologica Belgica 20100901

• Rationale for delayed-start study of pramipexole in Parkinson's disease: the PROUD study.

  Movement disorders : official journal of the Movement Disorder Society 20100815

• Uptake of pramipexole by human organic cation transporters.

  Molecular pharmaceutics 20100802

• Drug therapies for Parkinson's disease: A database analysis of patient compliance and persistence.

  The American journal of geriatric pharmacotherapy 20100801

• Drug safety monitoring in patients of movement disorders of a tertiary care hospital.

  Indian journal of pharmacology 20100801

• Long-term open-label study of pramipexole in patients with primary restless legs syndrome.

  Journal of the neurological sciences 20100715

• Continuous dopaminergic stimulation by pramipexole is effective to treat early morning akinesia in animal models of Parkinson's disease: A pharmacokinetic-pharmacodynamic study using in vivo microdialysis in rats.

  Synapse (New York, N.Y.) 20100701

• Trials of neuroprotective therapies for Parkinson's disease: problems and limitations.

  Parkinsonism & related disorders 20100701

• Transdermal rotigotine for the perioperative management of Parkinson's disease.

  Journal of neural transmission (Vienna, Austria : 1996) 20100701

• Bipolar disorder: an update.

  Postgraduate medicine 20100701

• Coexisting huntingtin and SCA8 repeat expansion: case report of a severe complex neurodegenerative syndrome.

  Journal of the neurological sciences 20100615

• Dual motor response to l-dopa and nociceptin/orphanin FQ receptor antagonists in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) treated mice: Paradoxical inhibition is relieved by D(2)/D(3) receptor blockade.

  Experimental neurology 20100601

• Parametric approaches towards understanding the effects of the preferential D3 receptor agonist pramipexole on prepulse inhibition in rats.

  Pharmacology, biochemistry, and behavior 20100601

• Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder.

  CNS neuroscience & therapeutics 20100601

• Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial.

  The Lancet. Neurology 20100601

• Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial.

  The Lancet. Neurology 20100601

• Pramipexole for depression and motor symptoms in Parkinson's disease: can we kill two birds with one stone?

  The Lancet. Neurology 20100601

• Influence of compulsivity of drug abuse on dopaminergic modulation of attentional bias in stimulant dependence.

  Archives of general psychiatry 20100601

• Effects of pramipexole on impulsive choice in male wistar rats.

  Experimental and clinical psychopharmacology 20100601

• Acute dopamine-agonist treatment in restless legs syndrome: effects on sleep architecture and NREM sleep instability.

  Sleep 20100601

• Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents.

  Experimental neurobiology 20100601

• [Clinical studies on pramipexol retard].

  Ideggyogyaszati szemle 20100530

• Dopaminergic challenges in social anxiety disorder: evidence for dopamine D3 desensitisation following successful treatment with serotonergic antidepressants.

  Journal of psychopharmacology (Oxford, England) 20100501

• [Management of restless legs syndrome].

  Presse medicale (Paris, France : 1983) 20100501

• Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients.

  Archives of neurology 20100501

• Proposed dose equivalence between clonazepam and pramipexole in patients with restless legs syndrome.

  Progress in neuro-psychopharmacology & biological psychiatry 20100416

• Dopamine agonist induced compulsive eating behaviour in a Parkinson's disease patient.

  Pharmacy world & science : PWS 20100401

• Impulsive smoking in a patient with Parkinson's disease treated with dopamine agonists.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100401

• Pramipexole extended release: in Parkinson's disease.

  CNS drugs 20100401

• [Pathologic gambling as an adverse effect of the treatment for Parkinson's disease].

  Revista medica de Chile 20100401

• Compulsive habits in restless legs syndrome patients under dopaminergic treatment.

  Journal of the neurological sciences 20100315

• Patent watch.

  Nature reviews. Drug discovery 20100301

• [Clinical data of the prolonged-release formulation of ropinirole].

  Fortschritte der Neurologie-Psychiatrie 20100301

• The effects of pramipexole on prepulse inhibition and locomotor activity in C57BL/6J mice.

  Behavioural pharmacology 20100301

• Use of the D2/D3 receptor agonist pramipexole in treatment of rapid-cycling bipolar disorder in an elderly patient.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20100301

• Parkinson's disease: health-related quality of life, economic cost, and implications of early treatment.

  The American journal of managed care 20100301

• Othello syndrome in patients with Parkinson's disease.

  Psychiatria Danubina 20100301

• Pramipexole combined with levodopa improves motor function but reduces dyskinesia in MPTP-treated common marmosets.

  Movement disorders : official journal of the Movement Disorder Society 20100215

• Best practice guide for the treatment of REM sleep behavior disorder (RBD).

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20100215

• Progressive development of augmentation during long-term treatment with levodopa in restless legs syndrome: results of a prospective multi-center study.

  Journal of neurology 20100201

• Dopamine D2-D3 receptor heteromers: pharmacological properties and therapeutic significance.

  Current opinion in pharmacology 20100201

• Successful treatment of restless legs syndrome with the herbal prescription Yokukansan.

  Progress in neuro-psychopharmacology & biological psychiatry 20100201

• LSD but not lisuride disrupts prepulse inhibition in rats by activating the 5-HT(2A) receptor.

  Psychopharmacology 20100201

• Population in vitro-in vivo correlation model for pramipexole slow-release oral formulations.

  Pharmaceutical research 20100201

• Tolerability and safety of ropinirole versus other dopamine agonists and levodopa in the treatment of Parkinson's disease: meta-analysis of randomized controlled trials.

  Drug safety 20100201

• Randomized trials of dopamine agonists in restless legs syndrome: a systematic review, quality assessment, and meta-analysis.

  Clinical therapeutics 20100201

• Decision-making during gambling: an integration of cognitive and psychobiological approaches.

  Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20100127

• Zolpidem-induced sleep-related eating disorder.

  Journal of the neurological sciences 20100115

• Changes of cortical excitability after dopaminergic treatment in restless legs syndrome.

  Sleep medicine 20100101

• Effect of apomorphine on cognitive performance and sensorimotor gating in humans.

  Psychopharmacology 20100101

• Orally disintegrating selegiline in Parkinson patients with dopamine agonist-related adverse effects.

  Clinical neuropharmacology 20100101

• Impulse control disorder and piribedil: report of 5 cases.

  Clinical neuropharmacology 20100101

• Efficacy and safety of pramipexole in Japanese patients with primary restless legs syndrome: A polysomnographic randomized, double-blind, placebo-controlled study.

  Sleep medicine 20100101

• Why do some promising brain-stimulation devices fail the next steps of clinical development?

  Expert review of medical devices 20100101

• Effects of a dopamine agonist on the pharmacodynamics of levodopa in Parkinson disease.

  Archives of neurology 20100101

• Impulse control disorders with the use of dopaminergic agents in restless legs syndrome: a case-control study.

  Sleep 20100101

• Mitochondria-targeted antioxidant effects of S(-) and R(+) pramipexole.

  BMC pharmacology 20100101

• Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• [Effect of dopamine agonist pramipexole (mirapex) on tremor, affective disorders and quality of life in patients with Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• Delusion of Cotard's syndrome successfully treated with a dopamine agonist.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• Impact of dopamine agonists on compulsive behaviors: a case series of pramipexole-induced pathological gambling.

  Psychosomatics 20100101

• Gabapentin enacarbil - clinical efficacy in restless legs syndrome.

  Neuropsychiatric disease and treatment 20100101

• [Effects of the dopamine agonist mirapex (pramipexole) therapy on sleep disorders in Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• Efficacy and acceptability of selective serotonin reuptake inhibitors for the treatment of depression in Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials.

  BMC neurology 20100101

• Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management.

  Neuropsychiatric disease and treatment 20100101

• Carbidopa/levodopa/entacapone: the evidence for its place in the treatment of Parkinson's disease.

  Core evidence 20100101

• Use of near-infrared light to reduce symptoms associated with restless legs syndrome in a woman: a case report.

  Journal of medical case reports 20100101

• Remission of severe restless legs syndrome and periodic limb movements in sleep after bilateral excision of multiple foot neuromas: a case report.

  Journal of medical case reports 20100101

• Levodopa in the treatment of Parkinson's disease: an old drug still going strong.

  Clinical interventions in aging 20100101

• Therapeutic interventions and adjustments in the management of Parkinson disease: role of combined carbidopa/levodopa/entacapone (Stalevo).

  Neuropsychiatric disease and treatment 20100101

• Circadian rhythm disturbances in patients with Alzheimer's disease: a review.

  International journal of Alzheimer's disease 20100101

• Treatment of moderate to severe restless legs syndrome: 2-year safety and efficacy of rotigotine transdermal patch.

  BMC neurology 20100101

• Validation of a column liquid chromatographic method for the analysis of pramipexole and its five impurities.

  Journal of AOAC International 20100101

• The Impact of Clinical and Cognitive Variables on Social Functioning in Parkinson's Disease: Patient versus Examiner Estimates.

  Parkinson's disease 20100101

• Dopaminergic treatment in idiopathic restless legs syndrome: effects on subjective sleepiness.

  Clinical neuropharmacology 20100101

• Extrastriatal dopaminergic circuits of the Basal Ganglia.

  Frontiers in neuroanatomy 20100101

• Dopamine transporter binding is unaffected by L-DOPA administration in normal and MPTP-treated monkeys.

  PloS one 20100101

• Pramipexole extended release: a novel treatment option in Parkinson's disease.

  Parkinson's disease 20100101

• Effect of bromocriptine on the severity of ovarian hyperstimulation syndrome and outcome in high responders undergoing assisted reproduction.

  Journal of human reproductive sciences 20100101

• Synthesis, Characterization, and Biological Evaluation of certain 6-methyl-2(3H)-benzo-1, 3-thiazolyl-1'-ethylidene-2-(o, p- Substituted Acetophenones) Hydrazine Analogs.

  Journal of young pharmacists : JYP 20100101

• Pharmacotherapy in the management of early Parkinson's disease: cost-effectiveness and patient acceptability.

  ClinicoEconomics and outcomes research : CEOR 20100101

• Pathological gambling from dopamine agonist and deep brain stimulation of the nucleus tegmenti pedunculopontine.

  BMJ case reports 20100101

• Nonmotor symptoms in de novo Parkinson disease before and after dopaminergic treatment.

  Journal of the neurological sciences 20091215

• Dopamine agonist-induced antecollis in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20091215

• Pramipexole and gender identity disorder: expanding the phenotype of hypersexuality in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20091215

• Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells.

  Clinical and experimental pharmacology & physiology 20091201

• Neuroprotective effect of the antiparkinsonian drug pramipexole against nigrostriatal dopaminergic degeneration in rotenone-treated mice.

  Neurochemistry international 20091201

• Clinical and pharmacogenetic determinants for the discontinuation of non-ergoline dopamine agonists in Parkinson's disease.

  European journal of clinical pharmacology 20091201

• Dopamine agonists diminish value sensitivity of the orbitofrontal cortex: a trigger for pathological gambling in Parkinson's disease?

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20091201

• Potential neuroprotection mechanisms in PD: focus on dopamine agonist pramipexole.

  Current medical research and opinion 20091201

• Transdermal rotigotine: a clinically innovative dopamine-receptor agonist for the management of Parkinson's disease.

  Pharmacotherapy 20091201

• Dopamine receptor agonists and sleep disturbances in Parkinson's disease.

  Parkinsonism & related disorders 20091201

• Heterodimerization of dopamine receptors: new insights into functional and therapeutic significance.

  Parkinsonism & related disorders 20091201

• Role of dopamine receptor agonists in the treatment of early Parkinson's disease.

  Parkinsonism & related disorders 20091201

• Systematic review of the effect of dopamine receptor agonists on patient health-related quality of life.

  Parkinsonism & related disorders 20091201

• Treatment of restless legs syndrome.

  Parkinsonism & related disorders 20091201

• Dopamine receptor agonists and depression in Parkinson's disease.

  Parkinsonism & related disorders 20091201

• Transdermal delivery of dopamine receptor agonists.

  Parkinsonism & related disorders 20091201

• Reward networks in the brain as captured by connectivity measures.

  Frontiers in neuroscience 20091201

• Serotonin-norepinephrine reuptake inhibitors for pain control: premise and promise.

  Current neuropharmacology 20091201

• Biogenic amine depletion causes chronic muscular pain and tactile allodynia accompanied by depression: A putative animal model of fibromyalgia.

  Pain 20091101

• Neuroprotective effect of L-dopa on dopaminergic neurons is comparable to pramipexol in MPTP-treated animal model of Parkinson's disease: a direct comparison study.

  Journal of neurochemistry 20091101

• Oxidative neurodegeneration is prevented by UCP0045037, an allosteric modulator for the reduced form of DJ-1, a wild-type of familial Parkinson's disease-linked PARK7.

  International journal of molecular sciences 20091101

• Pharmacokinetics of a once-daily extended-release formulation of pramipexole in healthy male volunteers: three studies.

  Clinical therapeutics 20091101

• An open-label conversion study of pramipexole to ropinirole prolonged release in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20091030

• Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model.

  Experimental neurology 20091001

• Critical review of ropinirole and pramipexole - putative dopamine D(3)-receptor selective agonists - for the treatment of RLS.

  Journal of clinical pharmacy and therapeutics 20091001

• Fibromyalgia and myofascial pain syndrome-a dilemma.

  Indian journal of anaesthesia 20091001

• Managing pathological gambling in Parkinson's disease with enteral levodopa/carbidopa infusions.

  Movement disorders : official journal of the Movement Disorder Society 20090915

• Impulse control disorder behaviors associated with pramipexole used to treat fibromyalgia.

  Journal of gambling studies 20090901

• Long-term retention rate of pramipexole in the treatment of Parkinson's disease.

  European journal of clinical pharmacology 20090901

• Reward-learning and the novelty-seeking personality: a between- and within-subjects study of the effects of dopamine agonists on young Parkinson's patients.

  Brain : a journal of neurology 20090901

• Pramipexole effects on startle gating in rats and normal men.

  Psychopharmacology 20090901

• Dopamine agonists in 6-pyruvoyl tetrahydropterin synthase deficiency.

  Neurology 20090825

• Antidepressant effects of pramipexole, a dopamine D3/D2 receptor agonist, and 7-OH-DPAT, a dopamine D3 receptor agonist, in olfactory bulbectomized rats.

  European journal of pharmacology 20090815

• Disruption of nigrostriatal and cerebellothalamic pathways in dopamine responsive Holmes' tremor.

  Journal of neurology, neurosurgery, and psychiatry 20090801

• Using prepulse inhibition to detect functional D3 receptor antagonism: effects of WC10 and WC44.

  Pharmacology, biochemistry, and behavior 20090801

• REM sleep behavior disorder and narcolepsy.

  CNS & neurological disorders drug targets 20090801

• Pathological gambling associated with cabergoline in a case of recurrent depression.

  Drug discoveries & therapeutics 20090801

• Single dose of a dopamine agonist impairs reinforcement learning in humans: evidence from event-related potentials and computational modeling of striatal-cortical function.

  Human brain mapping 20090701

• Effects of pramipexole on the duration of immobility during the forced swim test in normal and ACTH-treated rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20090701

• Association of the DRD2 and DRD3 polymorphisms with response to pramipexole in Parkinson's disease patients.

  European journal of clinical pharmacology 20090701

• Homology modeling of adenosine A2A receptor and molecular docking for exploration of appropriate potent antagonists for treatment of Parkinson's disease.

  Current aging science 20090701

• A dose-ranging study of pramipexole for the symptomatic treatment of restless legs syndrome: polysomnographic evaluation of periodic leg movements and sleep disturbance.

  Sleep medicine 20090601

• Overnight switching from ergot-derived dopamine agonists to pramipexole in patients with Parkinson's disease: an open preliminary trial in Japan.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090601

• The effect of antipsychotics on the high-affinity state of D2 and D3 receptors: a positron emission tomography study With [11C]-(+)-PHNO.

  Archives of general psychiatry 20090601

• Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disorders.

  International journal of molecular sciences 20090601

• Pramipexole induced compulsive behaviors abate after initiation of rotigitine.

  Movement disorders : official journal of the Movement Disorder Society 20090515

• [Socioeconomic relevance of the idiopathic restless legs syndrome (RLS) in Germany: cost-of-illness study].

  Medizinische Klinik (Munich, Germany : 1983) 20090515

• Changes in artistic style and behaviour in Parkinson's disease: dopamine and creativity.

  Journal of neurology 20090501

• Long-term effect of initiating pramipexole vs levodopa in early Parkinson disease.

  Archives of neurology 20090501

• A case of compulsive behaviors observed in a restless legs syndrome patient treated with a dopamine agonist.

  Sleep 20090501

• Treatment of sleep disorders after traumatic brain injury.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090415

• Increased frequency and range of sexual behavior in a patient with Parkinson's disease after use of pramipexole: a case report.

  The journal of sexual medicine 20090401

• The discriminative stimulus effects of dopamine D2- and D3-preferring agonists in rats.

  Psychopharmacology 20090401

• Proerectile effects of dopamine D2-like agonists are mediated by the D3 receptor in rats and mice.

  The Journal of pharmacology and experimental therapeutics 20090401

• Diagnosis and management of restless legs syndrome in children.

  Sleep medicine reviews 20090401

• Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease.

  Mayo Clinic proceedings 20090401

• Effects of a dopamine receptor agonist and atropine sulfate on absorption of valproic acid in rats.

  Biomedical research (Tokyo, Japan) 20090401

• Dopamine and cognitive functioning in de novo subjects with Parkinson's disease: effects of pramipexole and pergolide on working memory.

  Neuropsychologia 20090401

• Mechanism and treatment of dropped head syndrome associated with parkinsonism.

  Parkinsonism & related disorders 20090301

• Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy.

  Parkinsonism & related disorders 20090301

• Antiparkinsonian drug-induced sleepiness: a double-blind placebo-controlled study of L-dopa, bromocriptine and pramipexole in healthy subjects.

  British journal of clinical pharmacology 20090301

• Involvement of the subthalamic nucleus in engagement with behaviourally relevant stimuli.

  The European journal of neuroscience 20090301

• Treatment options for restless legs syndrome.

  Expert opinion on pharmacotherapy 20090301

• Reversible Pisa syndrome in patients with Parkinson's disease on dopaminergic therapy.

  Journal of neurology 20090301

• Treatment of restless legs syndrome with iron infusion therapy.

  JAAPA : official journal of the American Academy of Physician Assistants 20090301

• Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element.

  International journal of molecular sciences 20090301

• Targeting the progression of Parkinson's disease.

  Current neuropharmacology 20090301

• Sustained administration of pramipexole modifies the spontaneous firing of dopamine, norepinephrine, and serotonin neurons in the rat brain.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090201

• Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of pramipexole in human plasma: application to a clinical pharmacokinetic study.

  Biomedical chromatography : BMC 20090201

• High risk factors for valvular heart disease from dopamine agonists in patients with Parkinson's disease.

  Journal of neural transmission (Vienna, Austria : 1996) 20090201

• Effective control of catatonia in Parkinson's disease by electroconvulsive therapy: a case report.

  European journal of neurology 20090201

• [Impulse control disorder induced by the use of dopamine agonists].

  Nederlands tijdschrift voor geneeskunde 20090117

• Cardiac and noncardiac fibrotic reactions caused by ergot-and nonergot-derived dopamine agonists.

  Movement disorders : official journal of the Movement Disorder Society 20090115

• [Pathological gambling induced by dopamine agonist].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20090110

• Cortisol release from adipose tissue by 11beta-hydroxysteroid dehydrogenase type 1 in humans.

  Diabetes 20090101

• The effect of pramipexole on mood and motivational symptoms in Parkinson's disease: a meta-analysis of placebo-controlled studies.

  Clinical therapeutics 20090101

• [The role of low-dose pramipexole in the treatment of treatment-resistant bipolar depression: a case report].

  Turk psikiyatri dergisi = Turkish journal of psychiatry 20090101

• Muscle modifications in fibromyalgic patients revealed by surface electromyography (SEMG) analysis.

  BMC musculoskeletal disorders 20090101

• Fibromyalgia: diagnosis and treatment options.

  Gender medicine 20090101

• A review of ropinirole prolonged release in Parkinson's disease.

  Clinical interventions in aging 20090101

• Dopamine Agonists and their risk to induce psychotic episodes in Parkinson's disease: a case-control study.

  BMC neurology 20090101

• Update on ropinirole in the treatment of Parkinson's disease.

  Neuropsychiatric disease and treatment 20090101

• Restless legs syndrome: differential diagnosis and management with rotigotine.

  Neuropsychiatric disease and treatment 20090101

• Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease.

  BMC neuroscience 20090101

• Cost effectiveness of rasagiline and pramipexole as treatment strategies in early Parkinson's disease in the UK setting: an economic Markov model evaluation.

  Drugs & aging 20090101

• [Influence of dopamine agonist pramipexole (mirapex) on tremor, cognitive and affective impairment in patients with Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

• Restless legs syndrome: differential diagnosis and management with pramipexole.

  Clinical interventions in aging 20090101

• [Fatigability in Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

• Levodopa/carbidopa/entacapone 200/50/200 mg (Stalevo 200) in the treatment of Parkinson's disease: a case series.

  Cases journal 20090101

• Visual hallucinations associated with varenicline: a case report.

  Journal of medical case reports 20090101

• Sleep disorders in Parkinson's disease.

  Neuropsychiatric disease and treatment 20090101

• Current and emerging treatments for amyotrophic lateral sclerosis.

  Neuropsychiatric disease and treatment 20090101

• Oxidative stress induction of DJ-1 protein in reactive astrocytes scavenges free radicals and reduces cell injury.

  Oxidative medicine and cellular longevity 20090101

• An unusual case of spontaneous multi vessel coronary artery dissection in an elderly patient: a case report.

  Cases journal 20090101

• [Restless leg syndrome: diagnosis and treatment].

  Glas. Srpska akademija nauka i umetnosti. Odeljenje medicinskih nauka 20090101

• Impulse control disorders in Parkinson's disease.

  F1000 medicine reports 20090101

• Hallucinations: Etiology and clinical implications.

  Industrial psychiatry journal 20090101

• Pramipexole as a possible cause of the syndrome of inappropriate antidiuresis.

  BMJ case reports 20090101

• Treatment of restless legs syndrome: an evidence-based review and implications for clinical practice.

  Movement disorders : official journal of the Movement Disorder Society 20081215

• Adenosine A(2A) receptors in Parkinson's disease treatment.

  Purinergic signalling 20081201

• Cabergoline and pramipexole fail to modify already established dyskinesias in an animal model of parkinsonism.

  Behavioural brain research 20081201

• Effect of pramipexole on RLS symptoms and sleep: a randomized, double-blind, placebo-controlled trial.

  Sleep medicine 20081201

• Pragmatic consideration of recent randomized, placebo-controlled clinical trials for treatment of fibromyalgia.

  Current pain and headache reports 20081201

• Heritable strain differences in sensitivity to the startle gating-disruptive effects of D2 but not D3 receptor stimulation.

  Behavioural pharmacology 20081201

• Toward achieving optimal response: understanding and managing antidepressant side effects.

  Dialogues in clinical neuroscience 20081201

• Treatment options and patient perspectives in the management of fibromyalgia: future trends.

  Neuropsychiatric disease and treatment 20081201

• New treatment options in the management of fibromyalgia: role of pregabalin.

  Neuropsychiatric disease and treatment 20081201

• Dopamine agonist-based strategies in the treatment of Parkinson's disease.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20081201

• Pharmacology and therapeutic potential of sigma(1) receptor ligands.

  Current neuropharmacology 20081201

• Neurophysiology of sleep and wakefulness: basic science and clinical implications.

  Current neuropharmacology 20081201

• Bromocriptine, a dopamine D(2) receptor agonist with the structure of the amino acid ergot alkaloids, induces neurite outgrowth in PC12 cells.

  European journal of pharmacology 20081119

• Hiccups and dopamine.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20081115

• [D3 agonism: an augmentative treatment in tardive dyskinesia? A case report].

  Psychiatrische Praxis 20081101

• Late onset dopa-responsive dystonia with tremor, gait freezing and behavioural disturbance and a normal dopamine transporter scan.

  Age and ageing 20081101

• [Restless-leg syndrome--possible unrecognized cause for insomnia and irritability in children].

  No to hattatsu = Brain and development 20081101

• Design, synthesis, and evaluation of potent and selective ligands for the dopamine 3 (D3) receptor with a novel in vivo behavioral profile.

  Journal of medicinal chemistry 20081009

• Meta-analysis of the efficacy and tolerability of pramipexole versus ropinirole in the treatment of restless legs syndrome.

  Sleep medicine 20081001

• Discontinuation of ropinirole and pramipexole in patients with Parkinson's disease: clinical practice versus clinical trials.

  European journal of clinical pharmacology 20081001

• Heart valve abnormalities in Parkinson's disease treated with dopamine agonists.

  Journal of neurology 20081001

• Cost-effectiveness of licensed treatment options for restless legs syndrome in the UK and Sweden.

  Current medical research and opinion 20081001

• Lack of effects of pramipexole on REM sleep behavior disorder in Parkinson disease.

  Sleep 20081001

• Analysis of the anti-Parkinson drug pramipexole in human urine by capillary electrophoresis with laser-induced fluorescence detection.

  Analytica chimica acta 20080919

• Interactions between antiparkinsonian drugs and ABCB1/P-glycoprotein at the blood-brain barrier in a rat brain endothelial cell model.

  Neuroscience letters 20080905

• Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression.

  Brain structure & function 20080901

• Sleep dysfunction in heart failure.

  Current treatment options in neurology 20080901

• Defining the boundaries of the response of sleep leg movements to a single dose of dopamine agonist.

  Sleep 20080901

• Unraveling depression in Parkinson's disease.

  European journal of neurology 20080901

• Dopaminergic modulation of semantic priming in Parkinson disease.

  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20080901

• [Pathological gambling and Parkinson disease].

  Brain and nerve = Shinkei kenkyu no shinpo 20080901

• [Case of a 30-year history of PARK6 --findings from functional imaging of the brain].

  Rinsho shinkeigaku = Clinical neurology 20080901

• Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part I: principles of functional organisation.

  Current neuropharmacology 20080901

• Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans.

  Current neuropharmacology 20080901

• Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity.

  Neuroscience letters 20080801

• Continuous subcutaneous infusion of pramipexole protects against lipopolysaccharide-induced dopaminergic cell death without affecting the inflammatory response.

  Experimental neurology 20080801

• Parkinson's disease and dopaminergic therapy--differential effects on movement, reward and cognition.

  Brain : a journal of neurology 20080801

• Beneficial effect of pramipexole for motor function and depression in Parkinson's disease.

  Neuropsychiatric disease and treatment 20080801

• Current approaches to the treatment of Parkinson's disease.

  Neuropsychiatric disease and treatment 20080801

• Psychiatric disorders and traumatic brain injury.

  Neuropsychiatric disease and treatment 20080801

• Synthesis and pharmacological investigation of novel 2-aminothiazole-privileged aporphines.

  Bioorganic & medicinal chemistry 20080715

• Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA.

  Journal of neural transmission (Vienna, Austria : 1996) 20080701

• Open-label study of the long-term efficacy and safety of pramipexole in patients with Restless Legs Syndrome (extension of the PRELUDE study).

  Sleep medicine 20080701

• Valproate-induced parkinsonism, glial cells and Alexander's disease.

  Progress in neuro-psychopharmacology & biological psychiatry 20080701

• [Two cases of patients with Parkinson's disease developing valvular heart disease while taking cabergoline].

  Rinsho shinkeigaku = Clinical neurology 20080701

• Recruitment of beta-arrestin2 to the dopamine D2 receptor: insights into anti-psychotic and anti-parkinsonian drug receptor signaling.

  Neuropharmacology 20080601

• Internal medicine: guidance to the diagnosis and management of restless legs syndrome.

  Southern medical journal 20080601

• Restless legs syndrome in women: a review.

  Journal of women's health (2002) 20080601

• A 77-year-old man with Parkinson's disease and hyperthermia.

  Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association 20080601

• Medications for restless legs syndrome in pregnancy.

  Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC 20080601

• Fatal intoxication using amantadine and pramipexole in a uremic patient.

  Acta neurologica Taiwanica 20080601

• Treatment of fragile X-associated tremor ataxia syndrome (FXTAS) and related neurological problems.

  Clinical interventions in aging 20080601

• The frequency of cardiac valvular regurgitation in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20080515

• Food restriction alters N'-propyl-4,5,6,7-tetrahydrobenzothiazole-2,6-diamine dihydrochloride (pramipexole)-induced yawning, hypothermia, and locomotor activity in rats: evidence for sensitization of dopamine D2 receptor-mediated effects.

  The Journal of pharmacology and experimental therapeutics 20080501

• Rotigotine transdermal system for the treatment of Parkinson's disease.

  Clinical therapeutics 20080501

• Medications used to treat Parkinson's disease and the risk of gambling.

  European journal of neurology 20080401

• Depressive symptoms in Parkinson's disease.

  European journal of neurology 20080401

• Protection against Parkinson's disease progression: clinical experience.

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20080401

• Pramipexole-induced psychosis in Parkinson's disease.

  Psychiatry and clinical neurosciences 20080401

• Dopamine agonists in Parkinson's disease.

  Expert review of neurotherapeutics 20080401

• Rotigotine: Parkinson's disease: a step backward.

  Prescrire international 20080401

• Update on the use of pramipexole in the treatment of Parkinson's disease.

  Neuropsychiatric disease and treatment 20080401

• Regulation of intracellular dopamine levels by dopaminergic drugs: involvement of vesicular monoamine transporter.

  European journal of pharmacology 20080317

• Dopaminergic drug-induced tics in PARK2-positive Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20080315

• A novel synthesis and pharmacological evaluation of a potential dopamine D1/D2 agonist: 1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol.

  Bioorganic & medicinal chemistry 20080315

• Genetic findings in Parkinson's disease and translation into treatment: a leading role for mitochondria?

  Genes, brain, and behavior 20080301

• Interaction between levodopa and enteral nutrition.

  The Annals of pharmacotherapy 20080301

• [Isolated pulmonary hypertension and pergolide].

  Revue neurologique 20080301

• Restless arms.

  Lancet (London, England) 20080209

• Single dose of a dopamine agonist impairs reinforcement learning in humans: behavioral evidence from a laboratory-based measure of reward responsiveness.

  Psychopharmacology 20080201

• [Fibromyalgia syndrome: new developments in pharmacotherapy].

  Zeitschrift fur Rheumatologie 20080201

• Restless legs syndrome in older adults.

  Clinics in geriatric medicine 20080201

• Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers.

  Journal of clinical psychopharmacology 20080201

• Burning mouth syndrome responsive to pramipexol.

  The journal of headache and pain 20080201

• Clinical experience with pramipexole in the treatment of restless legs syndrome.

  Expert opinion on drug metabolism & toxicology 20080201

• R+ pramipexole as a mitochondrially focused neuroprotectant: initial early phase studies in ALS.

  Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20080201

• Patterns of treatment for restless legs syndrome in primary care in the United Kingdom.

  Clinical therapeutics 20080201

• Depression in Parkinson's disease: health risks, etiology, and treatment options.

  Neuropsychiatric disease and treatment 20080201

• Optimizing levodopa therapy for Parkinson's disease with levodopa/carbidopa/entacapone: implications from a clinical and patient perspective.

  Neuropsychiatric disease and treatment 20080201

• Paradoxical aspects of parkinsonian tremor.

  Movement disorders : official journal of the Movement Disorder Society 20080130

• Pramipexole-induced antecollis in Parkinson's disease.

  Journal of the neurological sciences 20080115

• [Pramipexole and Parkinson's disease, an update].

  Revista de neurologia 20080101

• Pramipexole safely replaces ergot dopamine agonists with either rapid or slow switching.

  The Journal of international medical research 20080101

• Spotlight on rotigotine in Parkinson's disease.

  Drugs & aging 20080101

• Conversion from dopamine agonists to cabergoline: an open-label trial in 128 patients with advanced Parkinson disease.

  Clinical neuropharmacology 20080101

• Antiparkinsonian medication and pathological gambling.

  CNS drugs 20080101

• Development and evaluation of push-pull based osmotic delivery system for pramipexole.

  PDA journal of pharmaceutical science and technology 20080101

• Impact of newer pharmacological treatments on quality of life in patients with Parkinson's disease.

  CNS drugs 20080101

• Dopamine agonist increases risk taking but blunts reward-related brain activity.

  PloS one 20080101

• [Mirapex (pramipexole) in the treatment of non-motor disturbances in Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

• Haptic perception of object curvature in Parkinson's disease.

  PloS one 20080101

• A meta-analysis of the efficacy of fibromyalgia treatment according to level of care.

  Arthritis research & therapy 20080101

• [Restless-legs syndrome].

  Revue neurologique 20080101

• Cost effectiveness of pharmacotherapies in early Parkinson's disease.

  CNS drugs 20080101

• KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2, 6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis.

  CNS neuroscience & therapeutics 20080101

• HIV, visceral leishmaniasis and Parkinsonism combined with diabetes mellitus and hyperuricaemia: A case report.

  Cases journal 20080101

• [Pain and depression in Parkinson's disease: new therapeutic possibilities of pramipexole].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

• Pramipexole-induced dropped head syndrome in Parkinson's disease.

  Internal medicine (Tokyo, Japan) 20080101

• Pathological hypersexuality induced by dopamine replacement therapy in a patient with progressive supranuclear palsy.

  The Journal of neuropsychiatry and clinical neurosciences 20080101

• The treatment of Parkinson's disease with dopamine agonists.

  GMS health technology assessment 20080101

• Design and synthesis of a functionally selective D3 agonist and its in vivo delivery via the intranasal route.

  Bioorganic & medicinal chemistry letters 20071215

• Antiparkinson therapeutic potencies correlate with their affinities at dopamine D2(High) receptors.

  Synapse (New York, N.Y.) 20071201

• Reversible dopamine agonist induced anterocollis in a multiple system atrophy patient.

  Movement disorders : official journal of the Movement Disorder Society 20071115

• Comparison of pramipexole with and without domperidone co-administration on alertness, autonomic, and endocrine functions in healthy volunteers.

  British journal of clinical pharmacology 20071101

• Quantification of pramipexole in human plasma by liquid chromatography tandem mass spectrometry using tamsulosin as internal standard.

  Biomedical chromatography : BMC 20071101

• Rapid eye movement sleep behavior disorder.

  The Annals of pharmacotherapy 20071101

• Clinical practice regarding dopamine-agonist use and driving in Parkinson's disease.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20071101

• [Sleep disorder as alarm symptom].

  MMW Fortschritte der Medizin 20071025

• Dopaminergic agonists: possible neurorescue drugs endowed with independent and synergistic multisites of action.

  Neurochemical research 20071001

• Restless legs syndrome: nonpharmacologic and pharmacologic treatments.

  Geriatrics 20071001

• Fibrotic heart-valve reactions to dopamine-agonist treatment in Parkinson's disease.

  The Lancet. Neurology 20070901

• Restless legs syndrome and periodic limb movements during sleep: diagnosis and treatment.

  The neurologist 20070901

• MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine.

  Purinergic signalling 20070901

• Pramipexole and compulsive masturbation.

  Psychiatry (Edgmont (Pa. : Township)) 20070901

• Pramipexole prevents neurotoxicity induced by oligomers of beta-amyloid.

  European journal of pharmacology 20070827

• Using STN DBS and medication reduction as a strategy to treat pathological gambling in Parkinson's disease.

  Parkinsonism & related disorders 20070801

• Yawning and hypothermia in rats: effects of dopamine D3 and D2 agonists and antagonists.

  Psychopharmacology 20070801

• First night efficacy of pramipexole in restless legs syndrome and periodic leg movements.

  Sleep medicine 20070801

• Pramipexole in psychiatry: a systematic review of the literature.

  The Journal of clinical psychiatry 20070801

• Impact of pramipexole on the onset of levodopa-related dyskinesias.

  Movement disorders : official journal of the Movement Disorder Society 20070715

• Risk factors for somnolence, edema, and hallucinations in early Parkinson disease.

  Neurology 20070710

• Dopamine agonists and cardiac valvulopathy in Parkinson disease: a case-control study.

  Neurology 20070703

• Efficacy and safety of pramipexole in restless legs syndrome.

  Current neurology and neuroscience reports 20070701

• Use of the dopamine receptor agonist Mirapex in the treatment of Parkinson's disease.

  Neuroscience and behavioral physiology 20070701

• Orthostatic tremor in progressive supranuclear palsy.

  Movement disorders : official journal of the Movement Disorder Society 20070615

• Risk factors for the development of pedal edema in patients using pramipexole.

  Archives of neurology 20070601

• Efficacy of pramipexole and transdermal rotigotine in advanced Parkinson's disease: a double-blind, double-dummy, randomised controlled trial.

  The Lancet. Neurology 20070601

• Rasagiline - a novel MAO B inhibitor in Parkinson's disease therapy.

  Therapeutics and clinical risk management 20070601

• Continuous levodopa for advanced Parkinson's disease.

  Neuropsychiatric disease and treatment 20070601

• Efficacy and safety of pramipexole in restless legs syndrome.

  Neurology 20070508

• Sleep and aging: 2. Management of sleep disorders in older people.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070508

• Panic attack like episodes possibly associated with pramipexole therapy in Parkinson's disease.

  European journal of neurology 20070501

• Belly dancer's syndrome following central pontine and extrapontine myelinolysis.

  Movement disorders : official journal of the Movement Disorder Society 20070430

• Blood-brain barrier transport of pramipexole, a dopamine D2 agonist.

  Life sciences 20070403

• Responsiveness to a dopamine agent in Holmes tremor--case report.

  European journal of neurology 20070401

• The effects of L-3,4-dihydroxyphenylalanine and dopamine agonists on dopamine neurons in the progressive hemiparkinsonian rat models.

  Neurological research 20070401

• Pramipexole (Mirapex) for restless legs syndrome.

  The Medical letter on drugs and therapeutics 20070326

• Cardiac valve regurgitation with pergolide compared with nonergot agonists in Parkinson disease.

  Archives of neurology 20070301

• Treatment of juvenile Parkinson disease and the recurrent emergence of pathologic gambling.

  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20070301

• Novel neuroprotective mechanisms of pramipexole, an anti-Parkinson drug, against endogenous dopamine-mediated excitotoxicity.

  European journal of pharmacology 20070227

• Dopamine D3 receptor agonists for protection and repair in Parkinson's disease.

  Current opinion in pharmacology 20070201

• A case of mania following the use of pramipexole.

  The American journal of psychiatry 20070201

• Pramipexole: new indication. Restless legs: still no satisfactory drug treatment.

  Prescrire international 20070201

• Pathological gambling and dopamine agonists: A phenotype?

  Neuropsychiatric disease and treatment 20070201

• Impaired cognition and attention in adults: pharmacological management strategies.

  Neuropsychiatric disease and treatment 20070201

• The four As associated with pathological Parkinson disease gamblers: anxiety, anger, age, and agonists.

  Neuropsychiatric disease and treatment 20070201

• [Pramipexole therapy of restless legs syndrome].

  Ideggyogyaszati szemle 20070120

• Valvular heart disease in Parkinson's disease patients treated with dopamine agonists: a reader-blinded monocenter echocardiography study.

  Movement disorders : official journal of the Movement Disorder Society 20070115

• Efficacy of pramipexole in restless legs syndrome: a six-week, multicenter, randomized, double-blind study (effect-RLS study).

  Movement disorders : official journal of the Movement Disorder Society 20070115

• Restless arm symptoms as an extension of restless leg syndrome.

  Age and ageing 20070101

• Bipolar depression: a review of randomised clinical trials.

  Expert opinion on pharmacotherapy 20070101

• [Antidepressant effects of dopamine agonists. Experimental and clinical findings].

  Der Nervenarzt 20070101

• Drug adverse events and drop-out risk: a clinical case.

  Archives of gerontology and geriatrics 20070101

• Pramipexole in levodopa-treated Parkinson disease patients of African, Asian, and Hispanic heritage.

  Clinical neuropharmacology 20070101

• Pramipexole: in restless legs syndrome.

  CNS drugs 20070101

• The implications of using US-specific EQ-5D preference weights for cost-effectiveness evaluation.

  Medical decision making : an international journal of the Society for Medical Decision Making 20070101

• State of the art in restless legs syndrome therapy: practice recommendations for treating restless legs syndrome.

  Movement disorders : official journal of the Movement Disorder Society 20070101

• Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia.

  Arthritis research & therapy 20070101

• Medical management of levodopa-associated motor complications in patients with Parkinson's disease.

  CNS drugs 20070101

• High prevalence of extrapyramidal signs and symptoms in a group of Italian dental technicians.

  BMC neurology 20070101

• Gambling and increased sexual desire with dopaminergic medications in restless legs syndrome.

  Clinical neuropharmacology 20070101

• Overnight switch from oral dopaminergic agonists to transdermal rotigotine patch in subjects with Parkinson disease.

  Clinical neuropharmacology 20070101

• The effect of levodopa and dopamine agonists on optic nerve head in Parkinson disease.

  European journal of ophthalmology 20070101

• [Neuroprotective effect of dopamine agonists].

  Neurologia i neurochirurgia polska 20070101

• [Dopamine agonists in the treatment of motor complications in advanced Parkinson's disease].

  Neurologia i neurochirurgia polska 20070101

• Rotigotine transdermal patch: a review of its use in the management of Parkinson's disease.

  CNS drugs 20070101

• Cerebral and Extracranial Neurodegeneration are Strongly Coupled in Parkinson's Disease.

  The open neurology journal 20070101

• In 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates, the selective 5-hydroxytryptamine 1a agonist (R)-(+)-8-OHDPAT inhibits levodopa-induced dyskinesia but only with\ increased motor disability.

  The Journal of pharmacology and experimental therapeutics 20061201

• Long-term treatment with pramipexole in restless legs syndrome.

  European journal of neurology 20061201

• Neuroprotection in Parkinson models varies with toxin administration protocol.

  The European journal of neuroscience 20061201

• Epilepsy, parkinsonism, and neuroleptic malignant syndrome in a child.

  Journal of child neurology 20061201

• Factors associated with the development of motor fluctuations and dyskinesias in Parkinson disease.

  Archives of neurology 20061201

• End-of-dose deterioration in non ergolinic dopamine agonist monotherapy of Parkinson's disease.

  Journal of neurology 20061201

• Restless leg syndrome: is it a real problem?

  Therapeutics and clinical risk management 20061201

• Restless legs is a medical disorder and can be treated.

  Neuropsychiatric disease and treatment 20061201

• Pramipexole: new use for an old drug - the potential use of pramipexole in the treatment of restless legs syndrome.

  Neuropsychiatric disease and treatment 20061201

• Ropinirole for the treatment of restless legs syndrome.

  Neuropsychiatric disease and treatment 20061201

• Rotigotine transdermal system: a short review.

  Neuropsychiatric disease and treatment 20061201

• The biopsychosocial effects of restless legs syndrome (RLS).

  Neuropsychiatric disease and treatment 20061201

• Effects of restless legs syndrome (RLS) on sleep.

  Neuropsychiatric disease and treatment 20061201

• Comparison of pramipexole and modafinil on arousal, autonomic, and endocrine functions in healthy volunteers.

  Journal of psychopharmacology (Oxford, England) 20061101

• Increase in body weight after pramipexole treatment in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20061101

• Telogen effluvium associated with the dopamine agonist pramipexole in a 55-year-old woman with Parkinson's disease.

  Journal of the American Academy of Dermatology 20061101

• A dopamine agonist, pramipexole, and cognitive functions in Parkinson's disease.

  Journal of the neurological sciences 20061025

• Effects of the dopamine agonist pramipexole on depression, anhedonia and motor functioning in Parkinson's disease.

  Journal of the neurological sciences 20061025

• Dopamine agonists and cardiac valvulopathy in Parkinson disease: a case-control study.

  Neurology 20061010

• The weight of evidence for ropinirole in restless legs syndrome.

  European journal of neurology 20061001

• Dopamine agonist therapy in low-response children following traumatic brain injury.

  Journal of child neurology 20061001

• Efficacy and safety of pramipexole in restless legs syndrome.

  Neurology 20060926

• Controlled withdrawal of pramipexole after 6 months of open-label treatment in patients with restless legs syndrome.

  Movement disorders : official journal of the Movement Disorder Society 20060901

• Comparison of pramipexole and amisulpride on alertness, autonomic and endocrine functions in healthy volunteers.

  Psychopharmacology 20060901

• New-onset narcolepsy with cataplexy in a geriatric patient.

  Sleep medicine 20060901

• [Pathological gambling associated with pramipexole use in Parkinson's disease].

  Revista de neurologia 20060901

• [Treatment of Parkinson disease: therapeutic reserve of the dopaminergic agonist].

  Neurologia (Barcelona, Spain) 20060901

• Surrogate outcomes in neurology, psychiatry, and psychopharmacology.

  Dialogues in clinical neuroscience 20060901

• Patterns of prefrontal dysfunction in alcoholics with and without Korsakoff's syndrome, patients with Parkinson's disease, and patients with rupture and repair of the anterior communicating artery.

  Neuropsychiatric disease and treatment 20060901

• Religiosity in patients with Parkinson's disease.

  Neuropsychiatric disease and treatment 20060901

• Valvular heart disease in Parkinson's disease vs. controls: An echocardiographic study.

  Movement disorders : official journal of the Movement Disorder Society 20060801

• Efficacy and safety of pramipexole in idiopathic restless legs syndrome: a polysomnographic dose-finding study--the PRELUDE study.

  Sleep medicine 20060801

• Use of pramipexole in REM sleep behavior disorder: results from a case series.

  Sleep medicine 20060801

• [Reversible pathological gambling under treatment with pramipexole].

  Der Nervenarzt 20060801

• [Dopamine agonists for treatment of restless leg syndrome].

  Medizinische Monatsschrift fur Pharmazeuten 20060801

• Ergoline and non-ergoline derivatives in the treatment of Parkinson's disease.

  Journal of neurology 20060801

• A review of the receptor-binding and pharmacokinetic properties of dopamine agonists.

  Clinical therapeutics 20060801

• [A case of Parkinson's disease with neuroleptic malignant syndrome induced by paroxetine].

  Rinsho shinkeigaku = Clinical neurology 20060801

• Association of dopamine agonist use with impulse control disorders in Parkinson disease.

  Archives of neurology 20060701

• Validated chiral liquid chromatographic method for the enantiomeric separation of Pramipexole dihydrochloride monohydrate.

  Journal of pharmaceutical and biomedical analysis 20060616

• [More on therapeutic options in fibromyalgia].

  Medicina clinica 20060610

• [Restless legs syndrome: when uncontrollable urge to move afflicts the patient...].

  MMW Fortschritte der Medizin 20060608

• Chronic cluster headache responsive to pramipexole.

  Cephalalgia : an international journal of headache 20060601

• [Pre-launching of drugs--the RLS example].

  Lakartidningen 20060601

• Future prospects in depression research.

  Dialogues in clinical neuroscience 20060601

• Treatments in depression.

  Dialogues in clinical neuroscience 20060601

• [Case of juvenile parkinsonism in pregnancy].

  Rinsho shinkeigaku = Clinical neurology 20060601

• Restless legs syndrome: diagnosis and review of management options.

  Neuropsychiatric disease and treatment 20060601

• Pramipexole versus sertraline in the treatment of depression in Parkinson's disease: a national multicenter parallel-group randomized study.

  Journal of neurology 20060501

• Practice Parameter: treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology.

  Neurology 20060411

• Compulsive eating and weight gain related to dopamine agonist use.

  Movement disorders : official journal of the Movement Disorder Society 20060401

• Hiccups associated with dopamine agonists in Parkinson disease.

  Neurology 20060314

• Patch clamp reveals powerful blockade of the mitochondrial permeability transition pore by the D2-receptor agonist pramipexole.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

• Pramipexole protects against MPTP toxicity in non-human primates.

  Journal of neurochemistry 20060301

• Pramipexole for the treatment of restless legs syndrome.

  Expert opinion on pharmacotherapy 20060301

• Restless legs syndrome: facts & treatments. This strange malady affects 12 million Americans, many of whom go misdiagnosed or undiagnosed.

  Health news (Waltham, Mass.) 20060301

• Pramipexole: augmentation in the treatment of depressive symptoms.

  CNS spectrums 20060301

• Pisa syndrome without neuroleptic exposure in a patient with Parkinson's disease: case report.

  Movement disorders : official journal of the Movement Disorder Society 20060201

• Gambling and Parkinson disease.

  Archives of neurology 20060201

• Targeted antioxidative and neuroprotective properties of the dopamine agonist pramipexole and its nondopaminergic enantiomer SND919CL2x [(+)2-amino-4,5,6,7-tetrahydro-6-Lpropylamino-benzathiazole dihydrochloride].

  The Journal of pharmacology and experimental therapeutics 20060101

• The neurophysiology of the alternating leg muscle activation (ALMA) during sleep: study of one patient before and after treatment with pramipexole.

  Sleep medicine 20060101

• Pramipexole protects against H2O2-induced PC12 cell death.

  Naunyn-Schmiedeberg's archives of pharmacology 20060101

• Motor deficits in Parkinsonian reaching: dopa-sensitivity influenced by real-world task constraint.

  Journal of motor behavior 20060101

• Pramipexole versus levodopa in patients with early Parkinson's disease: effect on generic and disease-specific quality of life.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20060101

• Pharmacokinetic optimisation in the treatment of Parkinson's disease : an update.

  Clinical pharmacokinetics 20060101

• Proposed dose equivalence for rapid switch between dopamine receptor agonists in Parkinson's disease: a review of the literature.

  Clinical therapeutics 20060101

• Management of restless legs syndrome in patients on dialysis.

  Drugs 20060101

• Review of evidence that posttransplantation psychiatric treatment commonly affects prolactin levels and thereby influences graft fate.

  General hospital psychiatry 20060101

• Reversal learning in Parkinson's disease depends on medication status and outcome valence.

  Neuropsychologia 20060101

• Biology and therapy of fibromyalgia. New therapies in fibromyalgia.

  Arthritis research & therapy 20060101

• [Dopamine receptors agonists (mirapex) in the treatment of Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

• Pharmacological management of Huntington's disease: an evidence-based review.

  Current pharmaceutical design 20060101

• Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons.

  BMC psychiatry 20060101

• Biology and therapy of fibromyalgia. Genetic aspects of fibromyalgia syndrome.

  Arthritis research & therapy 20060101

• Phenomenology and management of cognitive and behavioral disorders in Parkinson's disease. Rise and logic of dementia in Parkinson's disease.

  Annals of general psychiatry 20060101

• Mechanism of synergistic action following co-treatment with pramipexole and fluoxetine or sertraline in the forced swimming test in rats.

  Pharmacological reports : PR 20060101

• Using pramipexole in neuropsychiatry: a cautionary note.

  The Journal of neuropsychiatry and clinical neurosciences 20060101

• [7-year experience in usage of mirapex in patients with different forms of primary parkinsonism].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

• A comparative study on the cost of new antibiotics and drugs of other therapeutic categories.

  PloS one 20060101

• The acute effect of a low dosage of pramipexole on severe idiopathic restless legs syndrome: an open-label trial.

  Neuropsychobiology 20060101

• Optimization of chiral separation of pramipexole on various polisaccharide stationary phases.

  Acta poloniae pharmaceutica 20060101

• Changing dopamine agonist treatment in Parkinson's disease: experiences with switching to pramipexole.

  Journal of neural transmission. Supplementum 20060101

• Restless Legs Syndrome: The underrecognised condition.

  The Libyan journal of medicine 20060101

• Parkinson's drug may relieve fibromyalgia pain.

  Health news (Waltham, Mass.) 20051201

• Prefrontal GABA levels in cocaine-dependent subjects increase with pramipexole and venlafaxine treatment.

  Psychopharmacology 20051101

• Antiparkinson concentrations of pramipexole and PHNO occupy dopamine D2(high) and D3(high) receptors.

  Synapse (New York, N.Y.) 20051101

• Present and future drug treatment for Parkinson's disease.

  Journal of neurology, neurosurgery, and psychiatry 20051101

• Dopamine D3 receptor-preferring agonists induce neurotrophic effects on mesencephalic dopamine neurons.

  The European journal of neuroscience 20051101

• Treatment of fibromyalgia: a changing of the guard.

  Women's health (London, England) 20051101

• [The role of dopaminagonists in the treatment of Parkinson's disease].

  Praxis 20051019

• Pathological gambling in Parkinson's disease.

  The Lancet. Neurology 20051001

• Neuroprotective therapy in Parkinson's disease: current status and new directions from experimental and genetic clues.

  Journal of clinical neurology (Seoul, Korea) 20051001

• Pharmacophore-guided drug discovery investigations leading to bioactive 5-aminotetrahydropyrazolopyridines. Implications for the binding mode of heterocyclic dopamine D3 receptor agonists.

  Journal of medicinal chemistry 20050908

• Pathological gambling caused by drugs used to treat Parkinson disease.

  Archives of neurology 20050901

• Pathological hypersexuality predominantly linked to adjuvant dopamine agonist therapy in Parkinson's disease and multiple system atrophy.

  Parkinsonism & related disorders 20050901

• Pramipexole in the treatment of Parkinson's disease: new developments.

  Expert review of neurotherapeutics 20050901

• A randomized, double-blind, placebo-controlled trial of pramipexole, a dopamine agonist, in patients with fibromyalgia receiving concomitant medications.

  Arthritis and rheumatism 20050801

• Sudden uncontrollable somnolence and medication use in Parkinson disease.

  Archives of neurology 20050801

• Pleuropulmonary fibrosis after long-term treatment with the dopamine agonist pergolide for Parkinson Disease.

  Archives of neurology 20050801

• REM sleep behaviour disorder: clinical profiles and pathophysiology.

  International review of psychiatry (Abingdon, England) 20050801

• Pramipexole has ameliorating effects on levodopa-induced abnormal dopamine turnover in parkinsonian striatum and quenching effects on dopamine-semiquinone generated in vitro.

  Neurological research 20050701

• A pilot double-blind placebo-controlled trial of low-dose pramipexole in sleep-related eating disorder.

  European journal of neurology 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Long-term efficacy and safety of pramipexole in advanced Parkinson's disease: results from a European multicenter trial.

  Movement disorders : official journal of the Movement Disorder Society 20050501

• Actometry in measuring the symptom severity of restless legs syndrome.

  European journal of neurology 20050501

• Evidence-based medical review update: pharmacological and surgical treatments of Parkinson's disease: 2001 to 2004.

  Movement disorders : official journal of the Movement Disorder Society 20050501

• CoMFA and CoMSIA investigations revealing novel insights into the binding modes of dopamine D3 receptor agonists.

  Journal of medicinal chemistry 20050407

• Transport of the dopamine D2 agonist pramipexole by rat organic cation transporters OCT1 and OCT2 in kidney.

  Drug metabolism and disposition: the biological fate of chemicals 20050401

• D3 dopamine receptors do not regulate neurogenesis in the subventricular zone of adult mice.

  Neurobiology of disease 20050401

• Pramipexole, ropinirole, and mania in Parkinson's disease.

  The American journal of psychiatry 20050401

• Biological effects of pramipexole on dopaminergic neuron-associated genes: relevance to neuroprotection.

  Neuroscience letters 20050329

• 'Levodopa phobia': a new iatrogenic cause of disability in Parkinson disease.

  Neurology 20050308

• Efficacy screening trials of paroxetine, pentoxifylline, riluzole, pramipexole and venlafaxine in cocaine dependence.

  Addiction (Abingdon, England) 20050301

• Sleep attacks in patients receiving dopamine-receptor agonists.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050301

• Recovery from parkinson syndrome and prolonged visually evoked potentials in hepatic encephalopathy.

  Metabolic brain disease 20050301

• Mild cognitive impairment in Parkinson's disease: the challenge and the promise.

  Neuropsychiatric disease and treatment 20050301

• Molecular studies probe bipolar disorder.

  JAMA 20050202

• Pergolide effect on cognitive functions in early-mild Parkinson's disease.

  Journal of neural transmission (Vienna, Austria : 1996) 20050201

• Sleep episodes and daytime somnolence as result of individual susceptibility to different dopaminergic drugs in a PD patient: a polysomnographic study.

  Journal of the neurological sciences 20050115

• A randomly assigned double-blind cross-over study examining the relative anti-parkinsonian tremor effects of pramipexole and pergolide.

  European journal of neurology 20050101

• Cognitive performance in people with Parkinson's disease and mild or moderate depression: effects of dopamine agonists in an add-on to L-dopa therapy.

  European journal of neurology 20050101

• Diagnosis and management of patients with bipolar II disorder.

  The Journal of clinical psychiatry 20050101

• [Organ changes induced by ergot derivative dopamine agonist drugs: time to change treatment guidelines in Parkinson's disease?].

  Casopis lekaru ceskych 20050101

• Anhedonia, depression, and motor functioning in Parkinson's disease during treatment with pramipexole.

  The Journal of neuropsychiatry and clinical neurosciences 20050101

• [Syndrome of inappropriate ADH secretion (SIADH) induced by pramipexole in a patient with Parkinson's disease].

  Nihon Jinzo Gakkai shi 20050101

• Newer treatment studies for bipolar depression.

  Bipolar disorders 20050101

• Fluoxetine versus other types of pharmacotherapy for depression.

  The Cochrane database of systematic reviews 20050101

• Pramipexole and levodopa in early Parkinson's disease: dynamic changes in cost effectiveness.

  PharmacoEconomics 20050101

• Short review on dopamine agonists: insight into clinical and research studies relevant to Parkinson's disease.

  Pharmacological reports : PR 20050101

• Pramipexole in restless legs syndrome: an evidence-based review of its effectiveness on clinical outcomes.

  Core evidence 20050101

• Pramipexole protects against apoptotic cell death by non-dopaminergic mechanisms.

  Journal of neurochemistry 20041201

• [Pramipexole for intractable hiccups].

  Medicina clinica 20041113

• Switching from ergot to nonergot dopamine agonists in Parkinson's disease: a clinical series and five-drug dose conversion table.

  Movement disorders : official journal of the Movement Disorder Society 20041101

• Predictors of sudden onset of sleep in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20041101

• Involvement of dopamine D(2)/D(3) receptors and BDNF in the neuroprotective effects of S32504 and pramipexole against 1-methyl-4-phenylpyridinium in terminally differentiated SH-SY5Y cells.

  Experimental neurology 20041101

• Periodic leg movements in prepubertal children with sleep disturbance.

  Developmental medicine and child neurology 20041101

• [Diseases other than Parkinson's disease presenting with parkinsonism].

  Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20041101

• Effect of monoamine reuptake inhibitor NS 2330 in advanced Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20041001

• The activity of pramipexole in the mouse forced swim test is mediated by D2 rather than D3 receptors.

  Psychopharmacology 20040901

• SL25.1131 [3(S),3a(S)-3-methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a new, reversible, and mixed inhibitor of monoamine oxidase-A and monoamine oxidase-B: biochemical and behavioral profile.

  The Journal of pharmacology and experimental therapeutics 20040901

• Pramipexole-treated Parkinson's disease during pregnancy.

  Movement disorders : official journal of the Movement Disorder Society 20040901

• [Treatment for patients with early Parkinson's disease].

  Nihon rinsho. Japanese journal of clinical medicine 20040901

• Depression and Parkinson's disease.

  Journal of neurology 20040901

• Drug treatment of Parkinson's disease.

  Dialogues in clinical neuroscience 20040901

• Imaging dopamine neurotransmission in Parkinson's disease: biomarker versus surrogate end point.

  Dialogues in clinical neuroscience 20040901

• The effects of dopamine D3 agonists and antagonists in a nonhuman primate model of tardive dyskinesia.

  Pharmacology, biochemistry, and behavior 20040801

• Calming restless legs.

  Sleep 20040801

• Pramipexole for bipolar II depression: a placebo-controlled proof of concept study.

  Biological psychiatry 20040701

• Pramipexole vs levodopa as initial treatment for Parkinson disease: a 4-year randomized controlled trial.

  Archives of neurology 20040701

• [Pharmacological profiles and clinical effects of antiparkinsonian agent, pramipexole].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20040601

• Practice parameters for the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder.

  Sleep 20040501

• An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder.

  Sleep 20040501

• Pramipexole for the treatment of uremic restless legs in patients undergoing hemodialysis.

  Neurology 20040309

• Preliminary randomized, double-blind, placebo-controlled trial of pramipexole added to mood stabilizers for treatment-resistant bipolar depression.

  The American journal of psychiatry 20040301

• Conversion from dopamine agonists to pramipexole. An open-label trial in 227 patients with advanced Parkinson's disease.

  Journal of neurology 20040301

• Current perspectives in the management of treatment-resistant depression.

  Dialogues in clinical neuroscience 20040301

• Modulation of ATP levels alters the mode of hydrogen peroxide-induced cell death in primary cortical cultures: effects of putative neuroprotective agents.

  Brain research 20040130

• Slowing Parkinson's disease progression: recent dopamine agonist trials.

  Neurology 20040127

• Slowing Parkinson's disease progression: recent dopamine agonist trials.

  Neurology 20040127

• Augmentation and tolerance with long-term pramipexole treatment of restless legs syndrome (RLS).

  Sleep medicine 20040101

• Role of dopamine receptor agonists in the treatment of restless legs syndrome.

  CNS drugs 20040101

• Predictors of impaired daytime sleep and wakefulness in patients with Parkinson disease treated with older (ergot) vs newer (nonergot) dopamine agonists.

  Archives of neurology 20040101

• Quality of life in early Parkinson's disease: impact of dyskinesias and motor fluctuations.

  Movement disorders : official journal of the Movement Disorder Society 20040101

• [A comparative study of efficacy of dopamine receptors agonists and catechol-O-methyltransferase in the treatment of late stages of Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

• Terminally differentiated SH-SY5Y cells provide a model system for studying neuroprotective effects of dopamine agonists.

  Neurotoxicity research 20040101

• Low-dose pramipexole in the management of restless legs syndrome. An open label trial.

  Neuropsychobiology 20040101

• Restless legs symptoms in a patient with above knee amputations: a case of phantom restless legs.

  Clinical neuropharmacology 20040101

• Pramipexole v. levodopa as initial treatment for Parkinson's disease: a randomized clinical-economic trial.

  Medical decision making : an international journal of the Society for Medical Decision Making 20040101

• Low dose pramipexole is neuroprotective in the MPTP mouse model of Parkinson's disease, and downregulates the dopamine transporter via the D3 receptor.

  BMC biology 20040101

• Pramipexole in treatment-resistant depression: an extended follow-up.

  Depression and anxiety 20040101

• Vasculitis and nephritis caused by pramipexole, a second generation dopamine agonist.

  Clinical and experimental rheumatology 20040101

• Efficacy, safety, and tolerability of pramipexole in untreated and levodopa-treated patients with Parkinson's disease.

  Journal of the neurological sciences 20031215

• Pramipexole in Restless Legs syndrome. Evaluation by suggested immobilization test.

  Journal of neurology 20031201

• Fibromyalgia and pramipexole: promise and precaution.

  The Journal of rheumatology 20031201

• Comparing dopamine agonists in Parkinson's disease.

  Current opinion in neurology 20031201

• Diagnosis and treatment of sleep disorders: a brief review for clinicians.

  Dialogues in clinical neuroscience 20031201

• The effects of pramipexole in REM sleep behavior disorder.

  Neurology 20031125

• Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor.

  The Journal of biological chemistry 20031121

• Potent activation of dopamine D3/D2 heterodimers by the antiparkinsonian agents, S32504, pramipexole and ropinirole.

  Journal of neurochemistry 20031101

• Neuroprotective effects of the novel D3/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4-phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a comparison to ropinirole.

  Experimental neurology 20031101

• Randomized, double-blind, 3-month parallel study of the effects of pramipexole, pergolide, and placebo on Parkinsonian tremor.

  Movement disorders : official journal of the Movement Disorder Society 20031101

• Pramipexole in the management of restless legs syndrome: an extended study.

  Sleep 20031101

• 3,4-methylenedioxymethamphetamine (ecstasy) inhibits dyskinesia expression and normalizes motor activity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated primates.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20031008

• Current treatment options for restless legs syndrome.

  Expert opinion on pharmacotherapy 20031001

• Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum.

  Journal of neural transmission (Vienna, Austria : 1996) 20031001

• Randomized, double-blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20031001

• Sleep attacks in Parkinson's disease: a clinical and polysomnographic study.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20031001

• Oral anticoagulation for ECG tremor artefact simulating atrial fibrillation.

  Acta cardiologica 20031001

• Clinical strategies to prevent and delay motor complications.

  Neurology 20030923

• Treatment effects on nigrostriatal projection integrity in partial 6-OHDA lesions: comparison of L-DOPA and pramipexole.

  Experimental neurology 20030901

• The psychobiology of resilience and vulnerability to anxiety disorders: implications for prevention and treatment.

  Dialogues in clinical neuroscience 20030901

• Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms.

  European journal of pharmacology 20030815

• Pathological gambling associated with dopamine agonist therapy in Parkinson's disease.

  Neurology 20030812

• Pramipexole increases vesicular dopamine uptake: implications for treatment of Parkinson's neurodegeneration.

  European journal of pharmacology 20030808

• Current status of Parkinson's disease treatment in Korea.

  Parkinsonism & related disorders 20030801

• Neuroprotective mechanisms of antiparkinsonian dopamine D2-receptor subfamily agonists.

  Neurochemical research 20030701

• REAL and CALM: what have we learned?

  Movement disorders : official journal of the Movement Disorder Society 20030701

• Pramipexole and pergolide in the treatment of depression in Parkinson's disease: a national multicentre prospective randomized study.

  European journal of neurology 20030701

• Dual dopamine agonist treatment in Parkinson's disease.

  Journal of neurology 20030701

• Parkinson's disease: is the initial treatment established?

  Current neurology and neuroscience reports 20030701

• Assessment of sleepiness and unintended sleep in Parkinson's disease patients taking dopamine agonists.

  Sleep medicine 20030701

• The use of dopamine enhancing medications with children in low response states following brain injury.

  Brain injury 20030601

• The increased utilisation of dopamine agonists and the introduction of COMT inhibitors have not reduced levodopa consumption--a nation-wide perspective in Sweden.

  Parkinsonism & related disorders 20030601

• Sleep attacks, daytime sleepiness, and dopamine agonists in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20030601

• Dopamine agonist therapy for hyperprolactinemia.

  Clinical obstetrics and gynecology 20030601

• [Treatment of restless legs syndrome in uremic patients undergoing dialysis with pramipexole: preliminary results].

  Revista medica de Chile 20030601

• Reduction of oxidative stress in amyotrophic lateral sclerosis following pramipexole treatment.

  Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20030601

• Dihydroergocriptine in Parkinson's disease: clinical efficacy and comparison with other dopamine agonists.

  Acta neurologica Scandinavica 20030501

• The initial drug treatment of older patients with Parkinson's disease - consider an agonist, but don't demonise dopa.

  Age and ageing 20030501

• Efficacy, safety and cost of new drugs acting on the central nervous system.

  European journal of clinical pharmacology 20030501

• Pramipexole in comparison to l-dopa: a neuropsychological study.

  Journal of neural transmission (Vienna, Austria : 1996) 20030401

• [(123)I]beta-CIT SPECT is a useful method for monitoring dopaminergic degeneration in early stage Parkinson's disease.

  Journal of neurology, neurosurgery, and psychiatry 20030301

• Slowing Parkinson's disease progression: recent dopamine agonist trials.

  Neurology 20030211

• Double-blind, single-dose, cross-over study of the effects of pramipexole, pergolide, and placebo on rest tremor and UPDRS part III in Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20030201

• Piribedil-induced sleep attacks in Parkinson's disease.

  Fundamental & clinical pharmacology 20030201

• Sleep attacks--facts and fiction: a critical review.

  Advances in neurology 20030101

• Dopamine agonists induce episodes of irresistible daytime sleepiness.

  European neurology 20030101

• Sleepwalking and sleep terrors in prepubertal children: what triggers them?

  Pediatrics 20030101

• Loss of color vision during long-term treatment with pramipexole.

  Journal of neurology 20030101

• Multiple blood donations associated with iron deficiency in patients with restless legs syndrome.

  Mayo Clinic proceedings 20030101

• Comparison of the risk of adverse events with pramipexole and ropinirole in patients with Parkinson's disease: a meta-analysis.

  Drug safety 20030101

• Inhibitory effects of D2 agonists by striatal injection on excessive release of dopamine and hyperactivity induced by Bay K 8644 in rats.

  Neuroscience 20030101

• Advances in the pharmacological management of Parkinson disease.

  Journal of neural transmission. Supplementum 20030101

• Cabergoline, pramipexole and ropinirole used as monotherapy in early Parkinson's disease: an evidence-based comparison.

  Drugs & aging 20030101

• Pramipexole in routine clinical practice: a prospective observational trial in Parkinson's disease.

  CNS drugs 20030101

• Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics.

  Neurology 20021224

• Dopamine agonist monotherapy in Parkinson's disease.

  Lancet (London, England) 20021130

• Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes.

  The Journal of pharmacology and experimental therapeutics 20021101

• Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor.

  The Journal of pharmacology and experimental therapeutics 20021101

• Dopamine agonists and neuroprotection in Parkinson's disease.

  European journal of neurology 20021101

• Do dopamine agonists or levodopa modify Parkinson's disease progression?

  European journal of neurology 20021101

• Restless legs syndrome augmentation and pramipexole treatment.

  Sleep medicine 20021101

• Effect of daily dosing duration of direct and indirect dopamine receptor agonists: cocaine cross-tolerance following chronic regimens.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20021001

• Potential antidepressant properties of pramipexole detected in locomotor and operant behavioral investigations in mice.

  Psychopharmacology 20021001

• An evidence-based review of dopamine receptor agonists in the treatment of Parkinson's disease.

  Saudi medical journal 20021001

• Pramipexole in treatment-resistant depression: a 16-week naturalistic study.

  Bipolar disorders 20021001

• Neuroprotection in idiopathic Parkinson's disease.

  Journal of neurology 20021001

• Fused azaindole derivatives: molecular design, synthesis and in vitro pharmacology leading to the preferential dopamine D3 receptor agonist FAUC 725.

  Bioorganic & medicinal chemistry letters 20020902

• Combination of two different dopamine agonists in the management of Parkinson's disease.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20020901

• Two advances in the management of Parkinson disease.

  Cleveland Clinic journal of medicine 20020801

• [The usefulness of dopaminergic drugs in traumatic brain injury].

  Revista de neurologia 20020801

• Acute placebo-controlled sleep laboratory studies and clinical follow-up with pramipexole in restless legs syndrome.

  European archives of psychiatry and clinical neuroscience 20020801

• [Pramipexole in Parkinson disease. Results of a treatment observation].

  Der Nervenarzt 20020801

• Brain imaging to assess the effects of dopamine agonists on progression of Parkinson disease.

  JAMA 20020717

• The effects of speech therapy and pharmacological treatments on voice and speech in Parkinson s disease: a review of the literature.

  Current medicinal chemistry 20020701

• Sleep attacks in patients taking dopamine agonists: review.

  BMJ (Clinical research ed.) 20020622

• Pramipexole in patients with Parkinson's disease and marked drug resistant tremor: a randomised, double blind, placebo controlled multicentre study.

  Journal of neurology, neurosurgery, and psychiatry 20020601

• [Multiple latency test in a patient with episodes of sleep induced by pergolide].

  Revista de neurologia 20020601

• Gender and pramipexole effects on levodopa pharmacokinetics and pharmacodynamics.

  Neurology 20020514

• [Dopamine agonist is effective in Parkinson disease not only against tremor. Depression is also improved].

  MMW Fortschritte der Medizin 20020506

• A case of Parkinsonism due to lithium intoxication: treatment with Pramipexole.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20020501

• Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression.

  JAMA 20020403

• Alopecia induced by dopamine agonists.

  Neurology 20020312

• Influence of sildenafil on copulatory behaviour in sluggish or normal ejaculator male rats: a central dopamine mediated effect?

  Neuropharmacology 20020301

• Neuroprotection and dopamine agonists.

  Neurology 20020226

• Long-term studies of dopamine agonists.

  Neurology 20020226

• Restless legs syndrome: treatment with dopaminergic agents.

  Neurology 20020226

• Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma.

  Journal of neuroscience research 20020215

• Pramipexole for depression.

  The American journal of psychiatry 20020201

• A review of pramipexole and its clinical utility in Parkinson's disease.

  Expert opinion on pharmacotherapy 20020201

• [Rapid-eye-movement sleep disorders in Parkinson's disease].

  Revue neurologique 20020201

• Excessive daytime sleepiness and sudden-onset sleep in Parkinson disease: a survey by the Canadian Movement Disorders Group.

  JAMA 20020101

• Pergolide in the treatment of patients with early and advanced Parkinson's disease.

  Clinical neuropharmacology 20020101

• Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington's disease.

  Clinical neuropharmacology 20020101

• Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease.

  Clinical pharmacokinetics 20020101

• 'Sleep attacks' or 'unintended sleep episodes' occur with dopamine agonists: is this a class effect?

  Drug safety 20020101

• [Rhabdomyolysis as a complication of Parkinson's disease].

  Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20020101

• Choosing the right dopamine agonist for patients with Parkinson's disease.

  Current medical research and opinion 20020101

• Review: selegiline improves symptoms and levodopa is better than pramipexole for motor function in untreated Parkinson disease.

  ACP journal club 20020101

• DA agonists -- non-ergot derivatives: pramipexole: management of Parkinson's disease.

  Movement disorders : official journal of the Movement Disorder Society 20020101

• [Use of dopamine agonists in the treatment of Parkinson's disease].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

• Sleep disorders in Parkinson's disease: epidemiology and management.

  Drugs & aging 20020101

• Restless legs syndrome in the older adult: diagnosis and management.

  Drugs & aging 20020101

• Pramipexole in Parkinson's disease. A short-term study using the combined levodopa-dopamine agonist test.

  Functional neurology 20020101

• Daytime sleepiness and other sleep disorders in Parkinson's disease.

  Neurology 20011023

• Pramipexole: a nonergot dopamine agonist as drug therapy in Parkinson's disease.

  Expert review of neurotherapeutics 20010901

• Current advances in Parkinson's disease.

  Trends in neurosciences 20010701

• Modafinil and pramipexole-associated somnolence.

  Movement disorders : official journal of the Movement Disorder Society 20010701

• Adjunctive dopamine agonists in treatment-resistant bipolar II depression: an open case series.

  Pharmacopsychiatry 20010701

• Neuroprotective effects of pramipexole in young and aged MPTP-treated mice.

  Brain research 20010629

• Influence of L-dopa and pramipexole on striatal dopamine transporter in early PD.

  Neurology 20010612

• Newer dopamine agonists in the treatment of restless legs syndrome.

  The Annals of pharmacotherapy 20010501

• Release and aggregation of cytochrome c and alpha-synuclein are inhibited by the antiparkinsonian drugs, talipexole and pramipexole.

  European journal of pharmacology 20010406

• Antiparkinsonian drugs and 'sleep attacks'.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20010403

• Pramipexole augmentation in panic with agoraphobia.

  The American journal of psychiatry 20010301

• Antagonism of the discriminative stimulus effects of (+)-7-OH-DPAT by remoxipride but not PNU-99194A.

  Pharmacology, biochemistry, and behavior 20010301

• Current and emerging treatments in Parkinson's disease.

  Annals of the Academy of Medicine, Singapore 20010301

• Possible applications for dopaminergic agents following traumatic brain injury: part 2.

  The Journal of head trauma rehabilitation 20010201

• Efficacy and tolerability of dopamine agonists in a parkinsonian population.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20010201

• Switching from pergolide to pramipexole in patients with Parkinson's disease.

  Journal of neural transmission (Vienna, Austria : 1996) 20010101

• A study of excessive daytime sleepiness and its clinical significance in three groups of Parkinson's disease patients taking pramipexole, cabergoline and levodopa mono and combination therapy.

  Journal of neural transmission (Vienna, Austria : 1996) 20010101

• Dopamine agonists.

  Seminars in neurology 20010101

• Are dopamine receptor agonists neuroprotective in Parkinson's disease?

  Drugs & aging 20010101

• Sleep disorders in patients with Parkinson's disease: epidemiology and management.

  CNS drugs 20010101

• Economic and health-related quality of life considerations of new therapies in Parkinson's disease.

  PharmacoEconomics 20010101

• Increased risk of somnolence with the new dopamine agonists in patients with Parkinson's disease: a meta-analysis of randomised controlled trials.

  Drug safety 20010101

• Does combined treatment with novel antidepressants and a dopamine D3 receptor agonist reproduce cocaine discrimination in rats?

  Polish journal of pharmacology 20010101

• Locomotor hypoactivity and motor disturbances--behavioral effects induced by intracerebellar microinjections of dopaminergic DA-D2/D3 receptor agonists.

  Polish journal of pharmacology 20010101

• [Dopaminergic agonists in the treatment of Parkinson's disease].

  Revue medicale de Bruxelles 20001201

• ['Sleep attacks' in Parkinson patients. A side effect of nonergoline dopamine agonists or a class effect of dopamine agonists?].

  Der Nervenarzt 20000801

• Pramipexole-induced somnolence and episodes of daytime sleep.

  Movement disorders : official journal of the Movement Disorder Society 20000701

• Discriminative stimulus properties of the dopamine D3 receptor agonists, PD128,907 and 7-OH-DPAT: a comparative characterization with novel ligands at D3 versus D2 receptors.

  Neuropharmacology 20000214

• Role of dopamine D3 receptors in thermoregulation: a reappraisal.

  Neuroreport 20000117

• Clinical pharmacology of dopamine agonists.

  Pharmacotherapy 20000101

• Efficacy of pramipexole, a new dopamine receptor agonist, to relieve the parkinsonian-like muscle rigidity in rats.

  European journal of pharmacology 19991126

• Pramipexole treatment for cocaine cravings.

  The American journal of psychiatry 19991101

• Effects of pramipexole on contraversive rotation and functional motor impairments in 1-methyl-4-phenyl1,2,3, 6-tetrahydropyridine-induced chronic hemiparkinsonian monkeys.

  The Journal of pharmacology and experimental therapeutics 19981201

• Involvement of dopamine D2 receptors in the effect of cocaine on sexual behaviour and stretching-yawning of male rats.

  Neuropharmacology 19970601

• The behavioural effects of pramipexole, a novel dopamine receptor agonist.

  European journal of pharmacology 19970411

• Pramipexole binding and activation of cloned and expressed dopamine D2, D3 and D4 receptors.

  European journal of pharmacology 19950623

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