10519-96-7 | Potassium trimethylsilanolate

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$6.00	$5.00
10g	97%	in stock	$11.00	$8.00
25g	97%	in stock	$20.00	$14.00
100g	97%	in stock	$52.00	$37.00
500g	97%	in stock	$260.00	$182.00

Description

• Catalog Number: AB47764
• Chemical Name: Potassium trimethylsilanolate
• CAS Number: 10519-96-7
• Molecular Formula: C3H9KOSi
• Molecular Weight: 128.2868
• MDL Number: MFCD00013421
• SMILES: [O-][Si](C)(C)C.[K+]

Computed Properties

• Complexity: 32.3
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 1

Upstream Synthesis Route

Potassium trimethylsilanolate is a highly versatile compound that finds extensive use in chemical synthesis processes. This compound serves as a strong base in various reactions, aiding in deprotonation and condensation reactions. By virtue of its unique reactivity, potassium trimethylsilanolate is a valuable tool in the synthesis of organic compounds, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Its ability to promote various transformations makes it a key reagent in modern synthetic chemistry, enabling chemists to access a wide range of complex molecular structures. Additionally, potassium trimethylsilanolate is known for its compatibility with a variety of functional groups, allowing for its efficient and selective reactivity in diverse chemical transformations. Its application in chemical synthesis contributes significantly to the development of new materials, pharmaceuticals, and agrochemicals, highlighting its importance in advancing innovative research and industrial processes.

Literature

• Palladium-catalyzed cross-coupling reactions of silanolates: a paradigm shift in silicon-based cross-coupling reactions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20060623

• Cross-coupling of alkynylsilanols with aryl halides promoted by potassium trimethylsilanolate.

  The Journal of organic chemistry 20031114