105202-02-6 | 2-iodo-5-(trifluoromethyl)aniline

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$22.00	$16.00
1g	95%	in stock	$32.00	$22.00
5g	95%	in stock	$146.00	$103.00
10g	95%	in stock	$181.00	$127.00
100g	98%	in stock	$1,536.00	$1,075.00

Description

• Catalog Number: AE08355
• Chemical Name: 2-iodo-5-(trifluoromethyl)aniline
• CAS Number: 105202-02-6
• Molecular Formula: C7H5F3IN
• Molecular Weight: 287.0210
• MDL Number: MFCD04972658
• SMILES: Ic1ccc(cc1N)C(F)(F)F

Computed Properties

• Complexity: 159
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.8

Upstream Synthesis Route

The chemical compound Benzenamine, 2-iodo-5-(trifluoromethyl)-, is a versatile reagent commonly used in chemical synthesis processes. This compound serves as a valuable building block in the creation of various pharmaceuticals, agrochemicals, and fine chemicals. Its unique structure allows for the introduction of both iodine and trifluoromethyl functional groups, which are beneficial in enhancing the properties and activities of the final products.In organic synthesis, Benzenamine, 2-iodo-5-(trifluoromethyl)- can be utilized as a key intermediate for the construction of complex molecules through cross-coupling reactions, such as Suzuki-Miyaura, Heck, and Sonogashira couplings. These reactions enable the incorporation of the trifluoromethyl group into organic skeletons, which often leads to improved biological activities or enhanced chemical properties.Furthermore, the presence of the iodine atom in this compound can facilitate various transformation processes, including nucleophilic substitution reactions and metal-catalyzed transformations. This enables chemists to access a wide array of functionalized aromatic compounds and heterocycles, which are essential in the development of novel materials and bioactive molecules.Overall, the application of Benzenamine, 2-iodo-5-(trifluoromethyl)- in chemical synthesis showcases its significance as a valuable tool for the construction of diverse and complex chemical structures with potential applications across pharmaceutical, agrochemical, and material science industries.