1052686-60-8 | 2-Methoxypyrimidin-5-ylboronic acid pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$23.00	$17.00
250mg	98%	in stock	$41.00	$29.00
1g	98%	in stock	$103.00	$73.00
5g	98%	in stock	$435.00	$305.00

Description

• Catalog Number: AE18526
• Chemical Name: 2-Methoxypyrimidin-5-ylboronic acid pinacol ester
• CAS Number: 1052686-60-8
• Molecular Formula: C11H17BN2O3
• Molecular Weight: 236.0753
• MDL Number: MFCD13182190
• SMILES: COc1ncc(cn1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 262
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2

Upstream Synthesis Route

2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine is a valuable reagent widely utilized in chemical synthesis for the functionalization of organic compounds. This compound serves as a key building block in various reactions due to its unique structural properties and versatile reactivity. In particular, it is commonly employed in Suzuki-Miyaura cross-coupling reactions, where it acts as a boron-containing coupling partner to form biaryl compounds. Additionally, 2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine is used in the synthesis of pharmaceuticals, agrochemicals, materials, and other fine chemicals. Its ability to facilitate the formation of carbon-carbon bonds through palladium-catalyzed cross-coupling reactions makes it an indispensable tool for organic chemists seeking to access diverse molecular structures with high precision and efficiency.