10540-39-3 | 4'-Fluorobiphenyl-3-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$16.00	$11.00
1g	95%	in stock	$35.00	$24.00
5g	95%	in stock	$83.00	$58.00
25g	95%	in stock	$375.00	$262.00

Description

• Catalog Number: AD68436
• Chemical Name: 4'-Fluorobiphenyl-3-carboxylic acid
• CAS Number: 10540-39-3
• Molecular Formula: C13H9FO2
• Molecular Weight: 216.2078
• MDL Number: MFCD00452724
• SMILES: Fc1ccc(cc1)c1cccc(c1)C(=O)O

Computed Properties

• Complexity: 246
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 3.7

Upstream Synthesis Route

4'-Fluoro-[1,1'-biphenyl]-3-carboxylic acid is a valuable building block in chemical synthesis, particularly in the field of pharmaceuticals and materials science. This compound serves as a key intermediate in the synthesis of various organic molecules with important biological activities and properties.In chemical synthesis, 4'-Fluoro-[1,1'-biphenyl]-3-carboxylic acid is commonly used as a precursor for the construction of more complex structures. Its versatile reactivity allows for the introduction of fluorine atoms into the final target molecules, which can significantly impact their physicochemical properties and biological activities. This compound can be utilized in the development of new drugs, agrochemicals, and functional materials.Furthermore, the presence of the fluoro group in 4'-Fluoro-[1,1'-biphenyl]-3-carboxylic acid can also enable researchers to introduce chiral centers into the molecules, leading to the synthesis of enantiomerically pure compounds with enhanced biological efficacy and reduced off-target effects. Its unique structural features make it a valuable tool for the design and synthesis of novel chemical entities with targeted properties for various applications in the field of chemistry.

Literature

• Diflunisal analogues stabilize the native state of transthyretin. Potent inhibition of amyloidogenesis.

  Journal of medicinal chemistry 20040115