10541-83-0 | 4-(Methylamino)benzoic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$8.00	$6.00
25g	98%	in stock	$12.00	$9.00

Description

• Catalog Number: AB44721
• Chemical Name: 4-(Methylamino)benzoic acid
• CAS Number: 10541-83-0
• Molecular Formula: C8H9NO2
• Molecular Weight: 151.1626
• MDL Number: MFCD00002535
• SMILES: CNc1ccc(cc1)C(=O)O
• NSC Number: 102506

Computed Properties

• Complexity: 139
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: 2.2

Upstream Synthesis Route

4-(Methylamino)benzoic acid is a versatile compound frequently employed in chemical synthesis due to its unique structural properties and functionality. As a key intermediate in organic chemistry, this compound serves as a crucial building block in the synthesis of numerous pharmaceuticals, agrochemicals, and advanced materials. Its methylamino group allows for selective reactions, enabling the precise manipulation of molecular structures during the synthesis process. Additionally, the benzoic acid moiety provides a platform for further derivatization, enhancing the compound's synthetic flexibility and utility in diverse applications. In chemical synthesis, 4-(Methylamino)benzoic acid plays a pivotal role in the development of innovative compounds with tailored properties, making it a valuable tool for researchers and scientists in the field of organic chemistry.

Literature

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  Acta crystallographica. Section E, Structure reports online 20120301

• Bis(μ-3-hy-droxy-benzoato)-κO,O:O;κO:O,O-bis-[(3-hy-droxy-benzoato-κO,O')(iso-nicotinamide-κN)cadmium] tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20120201

• pH-dependent spectral properties of para-aminobenzoic acid and its derivatives.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111215

• Insights into the homocoupling reaction of 4-methylamino benzoic acid mediated by Trametes versicolor laccase.

  Molecular bioSystems 20111101

• Targeting metabolomics analysis of the sunscreen agent 2-ethylhexyl 4-(N,N-dimethylamino)benzoate in human urine by automated on-line solid-phase extraction-liquid chromatography-tandem mass spectrometry with liquid chromatography-time-of-flight/mass spectrometry confirmation.

  Journal of chromatography. A 20110520

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  Acta crystallographica. Section E, Structure reports online 20101201

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  Acta crystallographica. Section E, Structure reports online 20101201

• Tetra-aqua-bis[4-(methyl-amino)benzoato-κO]nickel(II).

  Acta crystallographica. Section E, Structure reports online 20100501

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  Acta crystallographica. Section E, Structure reports online 20100401

• Diazeniumdiolate mediated nitrosative stress alters nitric oxide homeostasis through intracellular calcium and S-glutathionylation of nitric oxide synthetase.

  PloS one 20100101

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  Acta crystallographica. Section E, Structure reports online 20091101

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  Acta crystallographica. Section E, Structure reports online 20091001

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  Acta crystallographica. Section E, Structure reports online 20090501

• Bis[4-(methyl-amino)benzoato-κO]bis-(nicotinamide-κN)zinc(II).

  Acta crystallographica. Section E, Structure reports online 20090101

• Amino benzoic acid modified silica--an improved catalyst for the mono-substituted product in the benzylation of toluene with benzyl chloride.

  Journal of colloid and interface science 20070701

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• Prodrug forms of N-[(4-deoxy-4-amino-10-methyl)pteroyl]glutamate-gamma-[psiP(O)(OH)]-glutarate, a potent inhibitor of folylpoly-gamma-glutamate synthetase: synthesis and hydrolytic stability.

  Journal of medicinal chemistry 20060126

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