10570-40-8 | 4-Methyl-4h-1,2,4-triazole

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$25.00	$17.00
250mg	97%	in stock	$35.00	$24.00
1g	97%	in stock	$38.00	$27.00
5g	97%	in stock	$131.00	$92.00
10g	97%	in stock	$262.00	$184.00
25g	97%	in stock	$654.00	$458.00

Description

• Catalog Number: AE22268
• Chemical Name: 4-Methyl-4h-1,2,4-triazole
• CAS Number: 10570-40-8
• Molecular Formula: C3H5N3
• Molecular Weight: 83.0919
• MDL Number: MFCD00490021
• SMILES: Cn1cnnc1

Computed Properties

• Complexity: 39.3
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• XLogP3: -0.6

Upstream Synthesis Route

4-Methyl-4H-1,2,4-triazole, also known as 4-Methyl-1H-1,2,4-triazole, is a versatile compound widely used in chemical synthesis. This heterocyclic compound is characterized by its unique structure containing a five-membered ring with three nitrogen atoms and one carbon atom. In chemical synthesis, 4-Methyl-4H-1,2,4-triazole is commonly employed as a building block or precursor in the preparation of various pharmaceuticals, agrochemicals, and coordination complexes. Its presence in the molecular structure of these compounds imparts desirable properties and functionalities, making it a valuable intermediate in organic chemistry.Due to its electron-rich nature and ability to participate in nucleophilic substitution reactions, 4-Methyl-4H-1,2,4-triazole serves as a key component in the synthesis of biologically active molecules like fungicides, herbicides, and antiviral agents. Additionally, its coordination capabilities make it a useful ligand in metal complex chemistry, enabling the formation of stable coordination complexes with transition metals.Overall, the application of 4-Methyl-4H-1,2,4-triazole in chemical synthesis highlights its significance as a versatile building block with diverse applications in the development of various functional compounds across different industries.

Literature

• Transformation products of 1,1-dimethylhydrazine and their distribution in soils of fall places of rocket carriers in Central Kazakhstan.

  The Science of the total environment 20120615

• Synthesis and antimycobacterial activity of 1,2,4-triazole 3-benzylsulfanyl derivatives.

  Farmaco (Societa chimica italiana : 1989) 20040401

• 4-methyl-1,2,4-triazol-3-yl heterocycle as an alternative to the 1-methylimidazol-5-yl moiety in the farnesyltransferase inhibitor ZARNESTRA.

  Bioorganic & medicinal chemistry letters 20031215