106018-85-3 | 2-(Trimethylsilyl)ethanesulfonyl chloride

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$219.00	$153.00
1g	95%	in stock	$527.00	$369.00

Description

• Catalog Number: AB43510
• Chemical Name: 2-(Trimethylsilyl)ethanesulfonyl chloride
• CAS Number: 106018-85-3
• Molecular Formula: C5H13ClO2SSi
• Molecular Weight: 200.759
• MDL Number: MFCD09265153
• SMILES: C[Si](CCS(=O)(=O)Cl)(C)C

Upstream Synthesis Route

2-(Trimethylsilyl)ethanesulfonyl chloride, commonly referred to as TESC, is a versatile reagent used in chemical synthesis for various transformations due to its unique properties. This compound is often employed in organic chemistry as a sulfonylating agent, enabling the introduction of sulfonyl groups into organic molecules.TESC is particularly useful in protecting hydroxyl (-OH) groups in alcohols, phenols, and carboxylic acids during multi-step synthesis. By selectively reacting with hydroxyl groups to form stable silyl ethers, TESC effectively shields these functional groups from undesired reactions and provides a means for their temporary removal at a later stage. This protection-deprotection strategy is crucial in complex organic synthesis where the manipulation of functional groups needs to be carefully controlled.Furthermore, TESC can also be utilized to introduce sulfonyl groups into various nucleophiles, such as amines and thiols, leading to the formation of sulfonyl derivatives with valuable applications in medicinal chemistry, material science, and natural product synthesis. Its ability to selectively functionalize nucleophiles makes TESC a valuable tool for the modification and diversification of organic molecules in a controlled manner.Overall, the application of 2-(Trimethylsilyl)ethanesulfonyl chloride in chemical synthesis offers chemists a powerful method for protecting functional groups, introducing sulfonyl moieties, and facilitating the construction of complex molecules with precision and efficiency.