106243-23-6 | 4-(1H-Imidazole-4(5)-yl) piperidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	96%	in stock	$113.00	$79.00
1g	96%	in stock	$322.00	$225.00
5g	96%	in stock	$1,224.00	$857.00

Description

• Catalog Number: AE08178
• Chemical Name: 4-(1H-Imidazole-4(5)-yl) piperidine
• CAS Number: 106243-23-6
• Molecular Formula: C8H13N3
• Molecular Weight: 151.2089
• MDL Number: MFCD02179572
• SMILES: N1CCC(CC1)c1nc[nH]c1

Computed Properties

• Complexity: 121
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.2

Upstream Synthesis Route

4-(1H-imidazol-4-yl)piperidine, also known as $name$, is a versatile compound widely utilized in chemical synthesis due to its unique structural properties and reactivity. This compound serves as a key building block in the creation of various pharmaceuticals, agrochemicals, and specialty chemicals. Its strategic placement of a piperidine ring and an imidazole moiety makes it a valuable intermediate in organic transformations.One of the primary applications of 4-(1H-imidazol-4-yl)piperidine is in the synthesis of bioactive compounds. By incorporating this molecule into target structures, chemists can modulate the biological activity and pharmacokinetic properties of the final product. Additionally, the imidazole ring in the molecule can participate in various types of chemical reactions, including nucleophilic substitutions, making it a versatile tool in complex molecule synthesis.Furthermore, 4-(1H-imidazol-4-yl)piperidine can be employed as a ligand in transition metal-catalyzed reactions, facilitating the formation of carbon-carbon and carbon-heteroatom bonds. Its ability to coordinate with metals enhances the selectivity and efficiency of these catalytic processes, enabling chemists to construct intricate molecular architectures with high precision.In summary, the strategic placement of an imidazole group on a piperidine scaffold makes 4-(1H-imidazol-4-yl)piperidine an indispensable component in the toolbox of synthetic chemists. Its versatility and reactivity open up a myriad of possibilities for the development of novel chemical entities with diverse applications in medicinal chemistry, materials science, and beyond.

Literature

• Synthesis and structure-activity relationships of conformationally constrained histamine H(3) receptor agonists.

  Journal of medicinal chemistry 20031204