1067239-08-0 | 1-Boc-3-hydroxypyrrolidine-3-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$85.00	$60.00
250mg	95%	in stock	$128.00	$90.00
500mg	95%	in stock	$192.00	$134.00
1g	95%	in stock	$325.00	$227.00
5g	95%	in stock	$944.00	$661.00

Description

• Catalog Number: AE28101
• Chemical Name: 1-Boc-3-hydroxypyrrolidine-3-carboxylic acid
• CAS Number: 1067239-08-0
• Molecular Formula: C10H17NO5
• Molecular Weight: 231.2457
• MDL Number: MFCD15071383
• SMILES: O=C(N1CCC(C1)(O)C(=O)O)OC(C)(C)C

Computed Properties

• Complexity: 309
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• Undefined Atom Stereocenter Count: 1

Upstream Synthesis Route

1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-3-carboxylic acid, often referred to as $name$, plays a crucial role in chemical synthesis as a versatile building block. This compound is commonly used as a key intermediate in the preparation of various pharmaceuticals and organic compounds due to its unique chemical properties.One of the primary applications of $name$ in chemical synthesis is as a protecting group in peptide synthesis. By selectively masking the reactive functional groups on amino acids, such as the amine group, $name$ enables precise control over the chemical reactions during peptide assembly. This protection strategy ensures the desired sequence of amino acids is achieved without unwanted side reactions.Additionally, $name$ serves as a valuable starting material for the synthesis of heterocyclic compounds. The presence of the hydroxyl and carboxylic acid functional groups on the pyrrolidine ring allows for further derivatization through a variety of chemical transformations. This versatility makes $name$ a highly useful tool in the construction of complex molecular structures.Furthermore, the tert-butoxycarbonyl (Boc) protecting group on $name$ can be selectively removed under mild conditions, making it a convenient choice for multi-step synthesis processes. This unique feature enhances the synthetic efficiency and overall yield of target molecules.In summary, 1-(tert-Butoxycarbonyl)-3-hydroxypyrrolidine-3-carboxylic acid, or $name$, is a valuable reagent in chemical synthesis, particularly in peptide chemistry and heterocyclic compound synthesis. Its role as a versatile building block underscores its importance in the development of novel pharmaceuticals and organic molecules.