1069-66-5 | sodium 2-propylpentanoate

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$16.00	$11.00
25g	97%	in stock	$38.00	$26.00
100g	97%	in stock	$98.00	$69.00
500g	97%	in stock	$323.00	$226.00

Description

• Catalog Number: AB47013
• Chemical Name: sodium 2-propylpentanoate
• CAS Number: 1069-66-5
• Molecular Formula: C8H15NaO2
• Molecular Weight: 166.1933
• MDL Number: MFCD00078604
• SMILES: CCCC(C(=O)[O-])CCC.[Na+]

Computed Properties

• Complexity: 98.3
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5

Upstream Synthesis Route

Application in Chemical Synthesis: Sodium 2-Propylpentanoate is a vital compound used in chemical synthesis processes. Its unique chemical properties make it a versatile reagent suitable for a variety of synthetic applications. This compound serves as an important intermediate in the production of various pharmaceuticals, agrochemicals, and organic compounds.One significant application of Sodium 2-Propylpentanoate in chemical synthesis is its use as a precursor in the preparation of esters, which are commonly employed in the fragrance and flavor industry. By reacting with different alcohols, Sodium 2-Propylpentanoate can form esters with diverse aromatic profiles, making it a valuable building block for creating a wide range of scents and tastes.In addition, Sodium 2-Propylpentanoate plays a crucial role in the synthesis of emollients and surfactants used in personal care products. Its ability to undergo esterification reactions with various fatty alcohols enables the production of high-quality moisturizers, skin creams, and surfactants with excellent spreading and emulsifying properties.Furthermore, Sodium 2-Propylpentanoate is utilized in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and drug intermediates. Its reactivity and compatibility with a variety of functional groups make it a valuable component in the production of drugs targeting various diseases and medical conditions.Overall, Sodium 2-Propylpentanoate is a versatile compound with broad applications in chemical synthesis, ranging from fragrance production to pharmaceutical manufacturing. Its importance in creating diverse chemical compounds underscores its significance in the field of organic chemistry and industrial applications.

Literature

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• The antiepileptic drug valproic acid restores T cell homeostasis and ameliorates pathogenesis of experimental autoimmune encephalomyelitis.

  The Journal of biological chemistry 20120817

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  The pharmacogenomics journal 20120801

• Unilateral basal-ganglia involvement likely due to valproate-induced hyperammonemic encephalopathy.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120801

• Embryotoxicity assessment of developmental neurotoxicants using a neuronal endpoint in the embryonic stem cell test.

  Journal of applied toxicology : JAT 20120801

• A severe valproate overdose with complete recovery in a newborn.

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• Variability of carbamazepine and valproate concentrations in elderly nursing home residents.

  Epilepsy research 20120801

• Effects of divalproex on smoking cue reactivity and cessation outcomes among smokers achieving initial abstinence.

  Experimental and clinical psychopharmacology 20120801

• Valproic acid affected the survival and invasiveness of human glioma cells through diverse mechanisms.

  Journal of neuro-oncology 20120801

• Valproic acid treatment may be harmful in non-dominant forms of retinitis pigmentosa.

  The British journal of ophthalmology 20120801

• Refining clinical features and therapeutic options of new daily persistent headache: a retrospective study of 63 patients in India.

  The journal of headache and pain 20120801

• Pharmacologic resuscitation decreases circulating cytokine-induced neutrophil chemoattractant-1 levels and attenuates hemorrhage-induced acute lung injury.

  Surgery 20120801

• Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans.

  Therapeutic drug monitoring 20120801

• Reduction in valproic acid-induced neural tube defects by maternal immune stimulation: role of apoptosis.

  Birth defects research. Part B, Developmental and reproductive toxicology 20120801

• Valproic acid augmentation in clozapine-associated hand-washing compulsion.

  Psychiatry and clinical neurosciences 20120801

• Peripheral oedema in quetiapine therapy.

  The Australian and New Zealand journal of psychiatry 20120801

• HDAC1/DNMT3A-containing complex is associated with suppression of Oct4 in cervical cancer cells.

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• Twist contributes to hormone resistance in breast cancer by downregulating estrogen receptor-α.

  Oncogene 20120705

• DRESS syndrome with fatal results induced by sodium valproate in a patient with brucellosis and a positive cytoplasmic antineutrophilic cytoplasmic antibody test result.

  Rheumatology international 20120701

• Histone deacetylase inhibitor treatment attenuates MAP kinase pathway activation and pulmonary inflammation following hemorrhagic shock in a rodent model.

  The Journal of surgical research 20120701

• Effect of valproic acid through regulation of NMDA receptor-ERK signaling in sleep deprivation rats.

  Journal of molecular neuroscience : MN 20120701

• Impact of valproic acid on dendritic cells function.

  Immunobiology 20120701

• Chronic treatment with lithium or valproate modulates the expression of Homer1b/c and its related genes Shank and Inositol 1,4,5-trisphosphate receptor.

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• Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL.

  Leukemia 20120701

• Bone mineral density in adult patients treated with various antiepileptic drugs.

  Seizure 20120701

• Valproic acid cooperates with hydralazine to augment the susceptibility of human osteosarcoma cells to Fas- and NK cell-mediated cell death.

  International journal of oncology 20120701

• Plasma leptin, neuropeptide Y, ghrelin, and adiponectin levels and carotid artery intima media thickness in epileptic children treated with valproate.

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• Management of cluster headache.

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• Hallucinations after withdrawal of valproic acid.

  Pediatrics 20120701

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  Pediatric neurology 20120701

• Synergistic killing of glioblastoma stem-like cells by bortezomib and HDAC inhibitors.

  Anticancer research 20120701

• Effect of histone deacetylase inhibitors trichostatin A and valproic acid on etoposide-induced apoptosis in leukemia cells.

  Anticancer research 20120701

• Anti-invasive effects and proapoptotic activity induction by the rexinoid IIF and valproic acid in combination on colon cancer cell lines.

  Anticancer research 20120701

• Drugs to prevent migraines are underused.

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• Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically.

  Cancer letters 20120628

• Exploration of the valproic acid binding site on histone deacetylase 8 using docking and molecular dynamic simulations.

  Journal of molecular modeling 20120601

• Atonic variant of benign childhood epilepsy with centrotemporal spikes (atonic-BECTS): a distinct electro-clinical syndrome.

  Brain & development 20120601

• The antiepileptic effect of sodium valproate during different phases of the estrous cycle in PTZ-induced seizures in rats.

  Journal of physiology and biochemistry 20120601

• Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activity.

  Leukemia & lymphoma 20120601

• Spinal muscular atrophy type III: trying to understand subtle functional change over time--a case report.

  Journal of child neurology 20120601

• Effect of valproic acid on the outcome of glioblastoma multiforme.

  British journal of neurosurgery 20120601

• Early life stress exacerbates cognitive dysfunction induced by d-amphetamine: amelioration by valproic acid.

  Journal of neural transmission (Vienna, Austria : 1996) 20120601

• A systematic review of randomized controlled trials on the theraputic effect of intravenous sodium valproate in status epilepticus.

  The International journal of neuroscience 20120601

• Anti-NMDA receptor encephalitis with the initial presentation of psychotic mania.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20120601

• A new approach on valproic acid induced hepatotoxicity: involvement of lysosomal membrane leakiness and cellular proteolysis.

  Toxicology in vitro : an international journal published in association with BIBRA 20120601

• Combined diazepam and HDAC inhibitor treatment protects against seizures and neuronal damage caused by soman exposure.

  Neurotoxicology 20120601

• Valproic acid attenuates blood-spinal cord barrier disruption by inhibiting matrix metalloprotease-9 activity and improves functional recovery after spinal cord injury.

  Journal of neurochemistry 20120601

• Epigenetic therapy with hydralazine and magnesium valproate reverses imatinib resistance in patients with chronic myeloid leukemia.

  Clinical lymphoma, myeloma & leukemia 20120601

• A novel liquefied gas based oral controlled release drug delivery system for liquid drug formulations.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120601

• Determination of drug toxicity using 3D spheroids constructed from an immortal human hepatocyte cell line.

  Toxicological sciences : an official journal of the Society of Toxicology 20120601

• Treatment of nuclear-donor cells or cloned zygotes with chromatin-modifying agents increases histone acetylation but does not improve full-term development of cloned cattle.

  Cellular reprogramming 20120601

• Valproic acid, a histone deacetylase inhibitor, enhances radiosensitivity in esophageal squamous cell carcinoma.

  International journal of oncology 20120601

• Novel evidence of the involvement of calreticulin in major psychiatric disorders.

  Progress in neuro-psychopharmacology & biological psychiatry 20120601

• Comparing efficacy of ECT with and without concurrent sodium valproate therapy in manic patients.

  The journal of ECT 20120601

• Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides.

  Bioorganic & medicinal chemistry 20120601

• Nonconvulsive status epilepticus in pediatric populations: diagnosis and management.

  Minerva pediatrica 20120601

• Levetiracetam-associated loss of libido and anhedonia.

  Epilepsy & behavior : E&B 20120601

• Neutropenia associated with the comedication of quetiapine and valproate in 2 elderly patients.

  Journal of clinical psychopharmacology 20120601

• A case of quetiapine XR and divalproex-associated neutropenia followed by successful use of ziprasidone.

  Journal of clinical psychopharmacology 20120601

• Evaluation of the antiepileptic effect of curcumin and Nigella sativa oil in the pilocarpine model of epilepsy in comparison with valproate.

  Epilepsy & behavior : E&B 20120601

• Valproate-induced hyperammonemic encephalopathy: a brief review.

  Current medical research and opinion 20120601

• Gingival overgrowth in partially edentulous ridges in an elderly female patient with epilepsy: a case report.

  Gerodontology 20120601

• Subclinical hypothyroidism during valproic acid therapy in children and adolescents with epilepsy.

  Neuropediatrics 20120601

• Glutamatergic effects of divalproex in adolescents with mania: a proton magnetic resonance spectroscopy study.

  Journal of the American Academy of Child and Adolescent Psychiatry 20120601

• A functional magnetic resonance imaging study of risperidone and divalproex.

  Journal of the American Academy of Child and Adolescent Psychiatry 20120601

• Valproate-acid-induced cutaneous leukocytoclastic vasculitis.

  Psychiatria Danubina 20120601

• Development and validation of a bioanalytical LC-UV method with solid-phase extraction for determination of valproic acid in saliva.

  Acta pharmaceutica (Zagreb, Croatia) 20120601

• [Clinical and electroencephalographic characteristics of Jeavons syndrome].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20120601

• Lamotrigine related myocarditis: case report.

  Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir 20120601

• Valproic acid enhances anti-tumor effect of mesenchymal stem cell mediated HSV-TK gene therapy in intracranial glioma.

  Biochemical and biophysical research communications 20120511

• Abbott pays $1.6bn for promoting off label use of valproic acid.

  BMJ (Clinical research ed.) 20120511

• [Efficacy and safety of the combined therapy of valproic acid and lamotrigine for epileptics].

  Zhonghua yi xue za zhi 20120508

• Novel molecular targeted therapies for refractory thyroid cancer.

  Head & neck 20120501

• Valproate reduces the glucuronidation of asenapine without affecting asenapine plasma concentrations.

  Journal of clinical pharmacology 20120501

• Long-term effectiveness of ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.

  Brain & development 20120501

• Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects.

  British journal of clinical pharmacology 20120501

• Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia.

  Leukemia 20120501

• Evaluation of subclinical hypothyroidism in ambulatory children with controlled epilepsy on valproate monotherapy.

  Journal of child neurology 20120501

• Use of single- and multi-drug regimens in the management of classic (idiopathic) trigeminal neuralgia: an 11-year experience at a single Sri Lankan institution.

  Journal of investigative and clinical dentistry 20120501

• Inhibition of 3-methylcrotonyl-CoA carboxylase explains the increased excretion of 3-hydroxyisovaleric acid in valproate-treated patients.

  Journal of inherited metabolic disease 20120501

• A randomized controlled trial of risperidone, lithium, or divalproex sodium for initial treatment of bipolar I disorder, manic or mixed phase, in children and adolescents.

  Archives of general psychiatry 20120501

• Simultaneous folate intake may prevent adverse effect of valproic acid on neurulating nervous system.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20120501

• Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study.

  HIV medicine 20120501

• Effect of valproic acid treatment on penile structure in prepubertal rats.

  Epilepsy research 20120501

• Bacopa monniera (L.) Wettst ameliorates behavioral alterations and oxidative markers in sodium valproate induced autism in rats.

  Neurochemical research 20120501

• The DRD2/ANKK1 gene is associated with response to add-on dextromethorphan treatment in bipolar disorder.

  Journal of affective disorders 20120501

• Safety and efficacy of olanzapine monotherapy and olanzapine with a mood stabilizer in 18-week treatment of manic/mixed episodes for Japanese patients with bipolar I disorder.

  Current medical research and opinion 20120501

• The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid.

  Seizure 20120501

• Valproic acid regulates antioxidant enzymes and prevents ischemia/reperfusion injury in the rat retina.

  Current eye research 20120501

• [Delirium caused by nonconvulsive status epilepticus].

  Psychiatrische Praxis 20120501

• Anticonvulsant activity of bisabolene sesquiterpenoids of Curcuma longa in zebrafish and mouse seizure models.

  Epilepsy & behavior : E&B 20120501

• Ionizing irradiation protection and mitigation of murine cells by carbamazepine is p53 and autophagy independent.

  In vivo (Athens, Greece) 20120501

• [Inhibitory effect of sodium valproate on human lung carcinoma SPC-A1 cell proliferation and the mechanism].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120501

• Valproic acid inhibits proliferation of EB virus-infected natural killer cells.

  Hematology (Amsterdam, Netherlands) 20120501

• Valproic acid mediates the synaptic excitatory/inhibitory balance through astrocytes--a preliminary study.

  Progress in neuro-psychopharmacology & biological psychiatry 20120427

• [The clinical course of a three year-old girl after overdose of valproic acid].

  Ugeskrift for laeger 20120423

• Drug treatment for spinal muscular atrophy types II and III.

  The Cochrane database of systematic reviews 20120418

• Prenatal exposure to valproic acid enhances synaptic plasticity in the medial prefrontal cortex and fear memories.

  Brain research bulletin 20120410

• Pilomotor seizure: when paroxysmal gooseflesh heralds brain tumor.

  Neurology 20120410

• Histone deacetylase inhibition by sodium valproate regulates polarization of macrophage subsets.

  DNA and cell biology 20120401

• Investigating the role of zinc in a rat model of epilepsy.

  CNS neuroscience & therapeutics 20120401

• Cancer risk in people with epilepsy using valproate-sodium.

  Acta neurologica Scandinavica 20120401

• Valproic acid in dementia: does an optimal dose exist?

  Journal of pharmacy practice 20120401

• Valproic acid reversed pathologic endothelial cell gene expression profile associated with ischemia-reperfusion injury in a swine hemorrhagic shock model.

  Journal of vascular surgery 20120401

• [Acute Intermittent porphyria and valproic acid].

  Revista clinica espanola 20120401

• Management of acute seizure and status epilepticus in pediatric emergency.

  Indian journal of pediatrics 20120401

• Valproic acid overcomes hypoxia-induced resistance to apoptosis.

  Oncology reports 20120401

• Using an exon microarray to identify a global profile of gene expression and alternative splicing in K562 cells exposed to sodium valproate.

  Oncology reports 20120401

• Valproic acid improves the tolerance for the stress in learned helplessness rats.

  Neuroscience research 20120401

• Developmental exposure to valproate and ethanol alters locomotor activity and retino-tectal projection area in zebrafish embryos.

  Reproductive toxicology (Elmsford, N.Y.) 20120401

• Valproate-induced teratogenesis in Japanese rice fish (Oryzias latipes) embryogenesis.

  Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120401

• Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.

  Behavioural brain research 20120401

• Amyloid precursor protein is a biomarker for transformed human pluripotent stem cells.

  The American journal of pathology 20120401

• Valproic acid and progestin inhibit lesion growth and reduce hyperalgesia in experimentally induced endometriosis in rats.

  Reproductive sciences (Thousand Oaks, Calif.) 20120401

• Valproate and the risk for congenital malformations: Is formulation and dosage regime important?

  Seizure 20120401

• Valproic acid improves the in vitro development competence of bovine somatic cell nuclear transfer embryos.

  Cellular reprogramming 20120401

• Disease-stabilizing treatment with all-trans retinoic acid and valproic acid in acute myeloid leukemia: serum hsp70 and hsp90 levels and serum cytokine profiles are determined by the disease, patient age, and anti-leukemic treatment.

  American journal of hematology 20120401

• Acute overdose of enteric-coated valproic acid and olanzapine: unusual presentation and delayed toxicity.

  Clinical toxicology (Philadelphia, Pa.) 20120401

• Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes.

  Pharmacotherapy 20120401

• Sulpiride-associated torsade de pointes in a woman with bipolar disorder.

  Psychiatry and clinical neurosciences 20120401

• Mood stabilizers for the treatment of behavioral and psychological symptoms of dementia: an update review.

  The Kaohsiung journal of medical sciences 20120401

• Myoclonus precipitated by oral suspension of oxcarbazepine in idiopathic generalized epilepsy.

  International journal of clinical pharmacology and therapeutics 20120401

• Efficacy and safety of innovator versus generic drugs in patients with epilepsy: a systematic review.

  Pharmacotherapy 20120401

• Thyroid hormones may contribute to vascular risk factors and atherosclerosis.

  Epilepsia 20120401

• [Methodological approach to inter 'guideline' variability in the management of bipolar disorders].

  L'Encephale 20120401

• Valproic acid-induced DRESS syndrome with acute liver failure.

  The Netherlands journal of medicine 20120401

• Subclinical rhythmic electrographic discharges of adults in a patient with migraine.

  Clinical EEG and neuroscience 20120401

• Effects of valproic acid, a histone deacetylase inhibitor, on improvement of locomotor function in rat spinal cord injury based on epigenetic science.

  Iranian biomedical journal 20120401

• The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation.

  Blood 20120329

• Controlled release of a highly hydrophilic API from lipid microspheres obtained by prilling: analysis of drug and water diffusion processes with X-ray-based methods.

  Journal of controlled release : official journal of the Controlled Release Society 20120328

• Acetylation: a novel link between double-strand break repair and autophagy.

  Cancer research 20120315

• The ratio of S-adenosylmethione and S-adenosyl-homocysteine is increased in the brains of newborn rats in a model of valproic acid teratogenicity.

  Toxicology 20120311

• Neuroprotective effects of valproic acid following transient global ischemia in rats.

  Life sciences 20120310

• Fish and Chips: a microfluidic perfusion platform for monitoring zebrafish development.

  Lab on a chip 20120307

• We must warn women about the risks of untreated, or ineffectively treated, epilepsy.

  BMJ (Clinical research ed.) 20120306

• Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.

  Head & neck 20120301

• Valproic acid increases SMN2 expression and modulates SF2/ASF and hnRNPA1 expression in SMA fibroblast cell lines.

  Brain & development 20120301

• Worsening of negative myoclonus by lamotrigine in a case of idiopathic focal epilepsy of children with long-term follow-up.

  Brain & development 20120301

• Effects of the abrupt switch from solution to modified-release granule formulation of valproate.

  Acta neurologica Scandinavica 20120301

• Effect of sodium valproate administration on brain neprilysin expression and memory in rats.

  Journal of molecular neuroscience : MN 20120301

• A systems biology approach to identify molecular pathways altered by HDAC inhibition in osteosarcoma.

  Journal of cellular biochemistry 20120301

• Valproate and high dosage of zotepine induced acute delirium: a case report.

  British journal of clinical pharmacology 20120301

• Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds.

  Disease models & mechanisms 20120301

• PPARγ potentiates anticancer effects of gemcitabine on human pancreatic cancer cells.

  International journal of oncology 20120301

• Valproic acid sensitizes human glioma cells for temozolomide and γ-radiation.

  Journal of neuro-oncology 20120301

• Simultaneous determination of valproic acid and 2-propyl-4-pentenoic acid for the prediction of clinical adverse effects in Chinese patients with epilepsy.

  Seizure 20120301

• Effects of valproate on glutamate metabolism in rat brain slices: a (13)C NMR study.

  Epilepsy research 20120301

• Superoxide dismutase 2 Val16Ala polymorphism is a risk factor for the valproic acid-related elevation of serum aminotransferases.

  Epilepsy research 20120301

• Downregulation of MUC1 expression and its recognition by CD8⁺ T cells on the surface of malignant pleural mesothelioma cells treated with HDACi.

  European journal of immunology 20120301

• Antiepileptic drugs for bipolar disorder and the risk of suicidal behavior: a 30-year observational study.

  The American journal of psychiatry 20120301

• Apparent clearance of valproic acid in elderly epileptic patients: estimation of the confounding effect of albumin concentration.

  Upsala journal of medical sciences 20120301

• Anticonvulsant profile of caprylic acid, a main constituent of the medium-chain triglyceride (MCT) ketogenic diet, in mice.

  Neuropharmacology 20120301

• Combination of valproic acid and ATRA restores RARβ2 expression and induces differentiation in cervical cancer through the PI3K/Akt pathway.

  Current molecular medicine 20120301

• Fourier transform infrared microspectroscopy identifies protein propionylation in histone deacetylase inhibitor treated glioma cells.

  Journal of biophotonics 20120301

• Long term effects of tetramine poisoning: an observational study.

  Clinical toxicology (Philadelphia, Pa.) 20120301

• Design and synthesis of novel 7-aminoquinazoline derivatives: antitumor and anticonvulsant activities.

  Bioorganic & medicinal chemistry letters 20120301

• Histone deacetylase inhibitors induced differentiation and accelerated mineralization of pulp-derived cells.

  Journal of endodontics 20120301

• Peri-ictal prolonged atrial fibrillation after generalized seizures: description of a case and etiopathological considerations.

  Epilepsy & behavior : E&B 20120301

• Repetitive transcranial magnetic stimulation safely administered after seizure.

  The journal of ECT 20120301

• Electroconvulsive therapy-induced migraine successfully treated with valproic acid.

  The journal of ECT 20120301

• Sleep disturbances in juvenile myoclonic epilepsy: a sleep questionnaire-based study.

  Epilepsy & behavior : E&B 20120301

• [Effect of TSA and VPA treatment on long-tailed macaque (Macaca fascicularis)-pig interspecies somatic cell nuclear transfer].

  Yi chuan = Hereditas 20120301

• The effect of valproic acid and oxcarbazepine on the distribution of adhesion molecules in embryo implantation.

  Toxicology 20120226

• Valproic acid affects the engraftment of TPO-expanded cord blood cells in NOD/SCID mice.

  Experimental cell research 20120215

• The role of miRNAs in complex formation and control.

  Bioinformatics (Oxford, England) 20120215

• Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210

• Proteomic study identified HSP 70 kDa protein 1A as a possible therapeutic target, in combination with histone deacetylase inhibitors, for lymphoid neoplasms.

  Journal of proteomics 20120202

• Ziprasidone with adjunctive mood stabilizer in the maintenance treatment of bipolar I disorder: long-term changes in weight and metabolic profiles.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120201

• Effect of valproic acid on acute lung injury in a rodent model of intestinal ischemia reperfusion.

  Resuscitation 20120201

• The prescribing of antiepileptic drugs for pregnant Australian women.

  The Australian & New Zealand journal of obstetrics & gynaecology 20120201

• A comparative study of the effects of low-dose topiramate versus sodium valproate in migraine prophylaxis.

  The International journal of neuroscience 20120201

• VPA inhibits breast cancer cell migration by specifically targeting HDAC2 and down-regulating Survivin.

  Molecular and cellular biochemistry 20120201

• Antitumor activities of valproic acid on Epstein-Barr virus-associated T and natural killer lymphoma cells.

  Cancer science 20120201

• Predictors of relapse or recurrence in bipolar I disorder.

  Journal of affective disorders 20120201

• The effect of valproic acid in alleviating early death in burn shock.

  Burns : journal of the International Society for Burn Injuries 20120201

• Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn).

  Toxicological sciences : an official journal of the Society of Toxicology 20120201

• Synthesis and anticonvulsant evaluation of dimethylethanolamine analogues of valproic acid and its tetramethylcyclopropyl analogue.

  Epilepsy research 20120201

• Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.

  The Journal of pharmacology and experimental therapeutics 20120201

• Stepwise synchronization through the corpus callosum is one cause of myoclonic jerks.

  World neurosurgery 20120201

• Valproic acid improves locomotion in vivo after SCI and axonal growth of neurons in vitro.

  Experimental neurology 20120201

• Asenapine as adjunctive treatment for acute mania associated with bipolar disorder: results of a 12-week core study and 40-week extension.

  Journal of clinical psychopharmacology 20120201

• Focal nonconvulsive seizures during detoxification for benzodiazepine abuse.

  Epilepsy & behavior : E&B 20120201

• Valproic Acid-related anticonvulsant hypersensitivity syndrome and subsequent olanzapine-related neutropenia and thrombocytopenia: a case report.

  Journal of clinical psychopharmacology 20120201

• Quetiapine- and valproate-associated neutropenia and thrombocytopenia after lamotrigine-induced Steven-Johnson syndrome.

  Journal of clinical psychopharmacology 20120201

• Ammonemia in bipolar patients on maintenance treatment with valproic acid.

  Journal of clinical psychopharmacology 20120201

• A case of acute valproic acid poisoning treated successfully with L-carnitine.

  European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20120201

• Synthesis and anticonvulsant activity of 1-(8-(benzyloxy)quinolin-2-yl)-6-substituted-4,6-diazaspiro[2,4]heptane-5,7-diones.

  European journal of medicinal chemistry 20120201

• This is your brain. This is your brain on treatment. Any questions?

  Journal of the American Academy of Child and Adolescent Psychiatry 20120201

• Risperidone and divalproex differentially engage the fronto-striato-temporal circuitry in pediatric mania: a pharmacological functional magnetic resonance imaging study.

  Journal of the American Academy of Child and Adolescent Psychiatry 20120201

• Drug interaction between valproic acid and meropenem: a case report.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20120201

• Atypical presentation of tardive dyskinesia associated with risperidone long-acting injection as maintenance treatment in bipolar affective disorder: a case report.

  Current drug safety 20120201

• Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, and N-acetylcysteine in chicken embryo model.

  Toxicology 20120127

• Juvenile myoclonic epilepsy.

  BMJ (Clinical research ed.) 20120126

• Pharmacotherapy impacts functional connectivity among affective circuits during response inhibition in pediatric mania.

  Behavioural brain research 20120115

• Histone deacetylase inhibitors induce growth arrest and differentiation in uveal melanoma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20120115

• Stem cell gene SALL4 suppresses transcription through recruitment of DNA methyltransferases.

  The Journal of biological chemistry 20120113

• Sodium valproate inhibits MDA-MB-231 breast cancer cell migration by upregulating NM23H1 expression.

  Genetics and molecular research : GMR 20120113

• [Neurology].

  Revue medicale suisse 20120111

• The interactions of atorvastatin and fluvastatin with carbamazepine, phenytoin and valproate in the mouse maximal electroshock seizure model.

  European journal of pharmacology 20120105

• Comparative efficacy of combination drug therapy in refractory epilepsy.

  Neurology 20120103

• Paradoxical increase in seizure frequency with valproate in nonketotic hyperglycinemia.

  Brain & development 20120101

• [Analysis of the valproic acid-meropenem interaction in hospitalised patients].

  Neurologia (Barcelona, Spain) 20120101

• The antiepileptic drug valproic acid and other medium-chain fatty acids acutely reduce phosphoinositide levels independently of inositol in Dictyostelium.

  Disease models & mechanisms 20120101

• Pharmacological treatment of deep brain stimulation-induced hypomania leads to clinical remission while preserving motor benefits.

  Neurocase 20120101

• Lithium, but not valproic acid or carbamazepine, suppresses impulsive-like action in rats.

  Psychopharmacology 20120101

• Long-term antiepileptic treatment with histone deacetylase inhibitors may reduce the risk of prostate cancer.

  European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20120101

• Takotsubo syndrome (TKS): a possible mechanism of sudden unexplained death in epilepsy (SUDEP).

  Seizure 20120101

• Endoplasmic reticulum stress and glycogen synthase kinase-3β activation in apolipoprotein E-deficient mouse models of accelerated atherosclerosis.

  Arteriosclerosis, thrombosis, and vascular biology 20120101

• Induction of superficial cortical layer neurons from mouse embryonic stem cells by valproic acid.

  Neuroscience research 20120101

• Rapid improvement of a complex migrainous episode with sodium valproate in a patient with CADASIL.

  The journal of headache and pain 20120101

• Design, synthesis and anticonvulsant evaluation of novel N-(4-substituted phenyl)-2-[4-(substituted) benzylidene]-hydrazinecarbothio amides.

  European journal of medicinal chemistry 20120101

• Effects of long-term antiepileptic drug monotherapy on vascular risk factors and atherosclerosis.

  Epilepsia 20120101

• Low-dose topiramate plus sodium divalproate for positive responders intolerant to full-dose monotherapy.

  Headache 20120101

• The influence of oral VPA on the required dose of propofol for sedation during dental treatment in patients with mental retardation: a prospective observer-blinded cohort study.

  Epilepsia 20120101

• Direct thrombectomy using the Penumbra thromboaspiration catheter for the treatment of cerebral venous sinus thrombosis.

  World neurosurgery 20120101

• Synthesis and anticonvulsant evaluation of some new 2,3,8-trisubstituted-4(3H)-quinazoline derivatives.

  Bioorganic & medicinal chemistry letters 20120101

• Lamotrigine XR conversion to monotherapy: first study using a historical control group.

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20120101

• Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation.

  Experimental eye research 20120101

• A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.

  Epilepsia 20120101

• 9-fluorenylmethyl chloroformate as a fluorescence-labeling reagent for derivatization of carboxylic acid moiety of sodium valproate using liquid chromatography/tandem mass spectrometry for binding characterization: a human pharmacokinetic study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120101

• Levocarnitine for valproic-acid-induced hyperammonemic encephalopathy.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120101

• Risk of mortality among individual antipsychotics in patients with dementia.

  The American journal of psychiatry 20120101

• Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature.

  The neurologist 20120101

• Serum protein levels of brain-derived neurotrophic factor and tropomyosin-related kinase B in bipolar disorder: effects of mood stabilizers.

  Neuropsychobiology 20120101

• Additional effect size measures helpful in understanding lithium and valproate trial results.

  The American journal of psychiatry 20120101

• Differential lithium efficacy in reducing suicidal behaviors compared with suicidal thoughts.

  The American journal of psychiatry 20120101

• Influence of antipsychotic drugs on human endogenous retrovirus (HERV) transcription in brain cells.

  PloS one 20120101

• [Epileptic asystole - a case report].

  Kardiologia polska 20120101

• Interaction of hydroalcoholic extract of Acorus calamus Linn. with sodium valproate and carbamazepine.

  Indian journal of experimental biology 20120101

• Valproate-induced hyperammonemic encephalopathy: an update on risk factors, clinical correlates and management.

  General hospital psychiatry 20120101

• DNMT inhibitors and HDAC inhibitors regulate E-cadherin and Bcl-2 expression in endometrial carcinoma in vitro and in vivo.

  Chemotherapy 20120101

• Epilepsy (generalised).

  BMJ clinical evidence 20120101

• [Case of a 13-year-old boy with hyponatremia due to lamotrigine-induced syndrome of inappropriate secretion of antidiuretic hormone].

  No to hattatsu = Brain and development 20120101

• Role of histone acetylation in the stimulatory effect of valproic acid on vascular endothelial tissue-type plasminogen activator expression.

  PloS one 20120101

• Persistent febrile illness with multisystem organ failure associated with clozapine.

  Internal medicine journal 20120101

• [Mood stabilizers].

  Nihon rinsho. Japanese journal of clinical medicine 20120101

• Effect of prenatal valproic acid exposure on cortical morphology in female mice.

  Journal of pharmacological sciences 20120101

• Levocarnitine-induced hypophosphatemia in a hemodialysis patient with acute valproic acid toxicity.

  The Journal of neuropsychiatry and clinical neurosciences 20120101

• Valproate in acute mania: is our practice evidence based?

  International journal of health care quality assurance 20120101

• Genes are often sheltered from the global histone hyperacetylation induced by HDAC inhibitors.

  PloS one 20120101

• Megadose bromazepam and zolpidem dependence: two case reports of treatment with flumazenil and valproate.

  Substance abuse 20120101

• Economic evaluation of anti-epileptic drug therapies with specific focus on teratogenic outcomes.

  Journal of medical economics 20120101

• Valproic acid induces hair regeneration in murine model and activates alkaline phosphatase activity in human dermal papilla cells.

  PloS one 20120101

• Valproic acid inhibits angiogenesis in vitro and glioma angiogenesis in vivo in the brain.

  Neurologia medico-chirurgica 20120101

• Effects of valproic acid and levetiracetam on viability and cell cycle regulatory genes expression in the OVCAR-3 cell line.

  Pharmacological reports : PR 20120101

• Combination treatment with aripiprazole and valproic acid for acute mania: an 8-week, single-blind, randomized controlled trial.

  Clinical neuropharmacology 20120101

• Gestational valproate alters BOLD activation in response to complex social and primary sensory stimuli.

  PloS one 20120101

• Carbamazepine treatment of bipolar disorder: a retrospective evaluation of naturalistic long-term outcomes.

  BMC psychiatry 20120101

• Sensory and motor characterization in the postnatal valproate rat model of autism.

  Developmental neuroscience 20120101

• The effects of oxcarbazepine and valproate therapies on growth in children with epilepsy.

  Endocrine research 20120101

• Valproic acid decreases the reparation capacity of irradiated MOLT-4 cells.

  Molekuliarnaia biologiia 20120101

• Influence of calcium channel blockers on anticonvulsant and antinociceptive activities of valproic acid in pentylenetetrazole-kindled mice.

  Pharmacological reports : PR 20120101

• Epigenetic approaches and methods in developmental toxicology: role of HDAC inhibition in teratogenic events.

  Methods in molecular biology (Clifton, N.J.) 20120101

• Combination of valproate and paroxetine in mice exposed to picrotoxin.

  International journal of nanomedicine 20120101

• Correlation between plasma ammonia level and serum trough concentration of free valproic acid in patients with epilepsy.

  Biological & pharmaceutical bulletin 20120101

• Evaluation of ovarian toxicity of sodium valproate (VPA) using cultured rat ovarian follicles.

  The Journal of toxicological sciences 20120101

• Analyzing gene expression profile in K562 cells exposed to sodium valproate using microarray combined with the connectivity map database.

  Journal of biomedicine & biotechnology 20120101

• Valproic acid downregulates the expression of MGMT and sensitizes temozolomide-resistant glioma cells.

  Journal of biomedicine & biotechnology 20120101

• Histone deacetylases regulate gonadotropin-releasing hormone I gene expression via modulating Otx2-driven transcriptional activity.

  PloS one 20120101

• [Valproate (depakine chrono) in adult patients with partial epilepsy: results of a multicentral prospective non-comparative study].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• [Concentrations of urine 6-sulfatoxymelatonin during the treatment of patients with epilepsy: a pilot clinical trial].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• Comparison of the effects of valproic acid and levetiracetam on apoptosis in the human ovarian cancer cell line OVCAR-3.

  Pharmacological reports : PR 20120101

• Abnormal semen parameters in bipolar men treated with valproate.

  Turk psikiyatri dergisi = Turkish journal of psychiatry 20120101

• Progressive neuropsychiatric and brain abnormalities after smoke inhalation.

  BMJ case reports 20120101

• Effects of rat prenatal exposure to valproic acid on behaviour and neuro-anatomy.

  Developmental neuroscience 20120101

• Valproic acid decreases urothelial cancer cell proliferation and induces thrombospondin-1 expression.

  BMC urology 20120101

• Histone deacetylases are required for amphibian tail and limb regeneration but not development.

  Mechanisms of development 20120101

• [Unipolar mania: a distinct entity or characteristic of manic preponderance?].

  Turk psikiyatri dergisi = Turkish journal of psychiatry 20120101

• [Treatment of prolonged migraine attack (status migrenosus)].

  Duodecim; laaketieteellinen aikakauskirja 20120101

• [Efficacy of the specific prolonged form of valproic acid (in the form of granules) in children with different forms of epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• [Complex therapy of idiopathic forms of epilepsy with small doses of valproates and levetiracetam].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• [Idiopathic generalized epilepsy in young women: choise of treatment strategy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101

• Effects of fluoxetine on the anticonvulsant action of valproate and ethosuximide in mouse model of myoclonic convulsions.

  Annals of agricultural and environmental medicine : AAEM 20120101

• [Mood stabilizers in the treatment of bipolar disorder mixed states].

  Rivista di psichiatria 20120101

• Valproic acid downregulates RBP4 and elicits hypervitaminosis A-teratogenesis--a kinetic analysis on retinol/retinoic acid homeostatic system.

  PloS one 20120101

• Valproate alters dopamine signaling in association with induction of Par-4 protein expression.

  PloS one 20120101

• Mechanism of growth inhibition of prostate cancer xenografts by valproic acid.

  Journal of biomedicine & biotechnology 20120101

• Effects of valproic acid on proliferation, apoptosis, angiogenesis and metastasis of ovarian cancer in vitro and in vivo.

  Asian Pacific journal of cancer prevention : APJCP 20120101

• Effects of UGT1A6, UGT2B7, and CYP2C9 genotypes on plasma concentrations of valproic acid in Chinese children with epilepsy.

  Drug metabolism and pharmacokinetics 20120101

• The anti-epileptic drug valproic acid (VPA) inhibits steroidogenesis in bovine theca and granulosa cells in vitro.

  PloS one 20120101

• The effects of neuropsychiatric drugs on glycogen synthase kinase-3 signaling.

  Neuroscience 20111229

• Potential autophagy enhancers attenuate rotenone-induced toxicity in SH-SY5Y.

  Neuroscience 20111229

• Histone deacetylase inhibitor valproic acid suppresses the growth and increases the androgen responsiveness of prostate cancer cells.

  Cancer letters 20111208

• Safety of long-term treatment of HAM/TSP patients with valproic acid.

  Blood 20111208

• Oxcarbazepine for acute affective episodes in bipolar disorder.

  The Cochrane database of systematic reviews 20111207

• Drug treatment for spinal muscular atrophy types II and III.

  The Cochrane database of systematic reviews 20111207

• Simple and accurate quantitative analysis of ten antiepileptic drugs in human plasma by liquid chromatography/tandem mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20111205

• Alterations of the gene expression profile in renal cell carcinoma after treatment with the histone deacetylase-inhibitor valproic acid and interferon-alpha.

  World journal of urology 20111201

• A double-blind, placebo-controlled, randomized phase III trial of chemotherapy plus epigenetic therapy with hydralazine valproate for advanced cervical cancer. Preliminary results.

  Medical oncology (Northwood, London, England) 20111201

• Histone deacetylases and mood disorders: epigenetic programming in gene-environment interactions.

  CNS neuroscience & therapeutics 20111201

• Tolerance to the prophylactic effects of carbamazepine and related mood stabilizers in the treatment of bipolar disorders.

  CNS neuroscience & therapeutics 20111201

• The regulatory role of histone deacetylase inhibitors in Fgf4 expression is dependent on the differentiation state of pluripotent stem cells.

  Journal of cellular physiology 20111201

• Valproic acid modulates superoxide dismutase, uric acid-independent FRAP and zinc in blood of adult epileptic patients.

  Biological trace element research 20111201

• Neurocutaneous melanosis: follow-up and literature review.

  Journal of neuroradiology. Journal de neuroradiologie 20111201

• Histone deacetylase inhibitor augments anti-tumor effect of gemcitabine and pegylated interferon-α on pancreatic cancer cells.

  International journal of clinical oncology 20111201

• Valproate versus diazepam for generalized convulsive status epilepticus: a pilot study.

  European journal of neurology 20111201

• Effect of D-cycloserine and valproic acid on the extinction of reinstated fear-conditioned responses and habituation of fear conditioning in healthy humans: a randomized controlled trial.

  Psychopharmacology 20111201

• Severe rhabdomyolysis caused by valproic Acid in a neonate with seizures and chromosomal abnormalities.

  Klinische Padiatrie 20111201

• The influence of valproic acid and carbamazepine treatment on serum biotin and zinc levels and on biotinidase activity.

  Journal of child neurology 20111201

• Effects of WIN 55,212-2 mesylate (a synthetic cannabinoid) on the protective action of clonazepam, ethosuximide, phenobarbital and valproate against pentylenetetrazole-induced clonic seizures in mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20111201

• Valproic acid induced differentiation and potentiated efficacy of taxol and nanotaxol for controlling growth of human glioblastoma LN18 and T98G cells.

  Neurochemical research 20111201

• Upregulation of NKG2D ligands and enhanced natural killer cell cytotoxicity by hydralazine and valproate.

  International journal of oncology 20111201

• A nonlinear two compartmental fractional derivative model.

  European journal of drug metabolism and pharmacokinetics 20111201

• A 12-month randomized, open-label study of the metabolic effects of olanzapine and risperidone in psychotic patients: influence of valproic acid augmentation.

  The Journal of clinical psychiatry 20111201

• Sodium valproate blocks the transforming growth factor (TGF)-β1 autocrine loop and attenuates the TGF-β1-induced collagen synthesis in a human hepatic stellate cell line.

  International journal of molecular medicine 20111201

• Chronic valproate treatment blocks D2-like receptor-mediated brain signaling via arachidonic acid in rats.

  Neuropharmacology 20111201

• Valproic acid utilizes the isoleucine breakdown pathway for its complete β-oxidation.

  Biochemical pharmacology 20111201

• Valproic acid increases formation of reactive oxygen species and induces apoptosis in postimplantation embryos: a role for oxidative stress in valproic acid-induced neural tube defects.

  Molecular pharmacology 20111201

• Side effects of phenobarbital in epilepsy: a systematic review.

  Epileptic disorders : international epilepsy journal with videotape 20111201

• Valproic acid-induced parkinsonism in the elderly: a comprehensive review of the literature.

  The American journal of geriatric pharmacotherapy 20111201

• Investigation on sodium valproate induced germ cell damage, oxidative stress and genotoxicity in male Swiss mice.

  Reproductive toxicology (Elmsford, N.Y.) 20111201

• Potentiation of mitomycin C tumoricidal activity for transitional cell carcinoma by histone deacetylase inhibitors in vitro.

  The Journal of urology 20111201

• Investigation of the metabolism of rufinamide and its interaction with valproate.

  Drug metabolism letters 20111201

• Histone deacetylase inhibitor significantly improved the cloning efficiency of porcine somatic cell nuclear transfer embryos.

  Cellular reprogramming 20111201

• Beneficial effects of mood stabilizers lithium, valproate and lamotrigine in experimental stroke models.

  Acta pharmacologica Sinica 20111201

• Role of Hounsfield units to distinguish pseudo-subarachnoid hemorrhage.

  Clinical toxicology (Philadelphia, Pa.) 20111201

• Aripiprazole plus divalproex for recently manic or mixed patients with bipolar I disorder: a 6-month, randomized, placebo-controlled, double-blind maintenance trial.

  Human psychopharmacology 20111201

• Valproate effects on generalized spike-wave discharges and photoparoxysmal response.

  Epilepsia 20111201

• Co-morbid disruptive behavior disorder and aggression predict functional outcomes and differential response to risperidone versus divalproex in pharmacotherapy for pediatric bipolar disorder.

  Journal of child and adolescent psychopharmacology 20111201

• [Eosinophilic pleural effusion related to taking valproic acid].

  Revue de pneumologie clinique 20111201

• Protective effects of valproic acid against airway hyperresponsiveness and airway remodeling in a mouse model of allergic airways disease.

  Epigenetics 20111201

• [Lithium and anticonvulsants in bipolar depression].

  L'Encephale 20111201

• Valproic acid phase shifts the rhythmic expression of Period2::Luciferase.

  Journal of biological rhythms 20111201

• Analysis of acylcarnitine levels by tandem mass spectrometry in epileptic children receiving valproate and oxcarbazepine.

  Epileptic disorders : international epilepsy journal with videotape 20111201

• Amygdala functional connectivity predicts pharmacotherapy outcome in pediatric bipolar disorder.

  Brain connectivity 20111201

• Using interleaved transcranial magnetic stimulation/functional magnetic resonance imaging (fMRI) and dynamic causal modeling to understand the discrete circuit specific changes of medications: lamotrigine and valproic acid changes in motor or prefrontal effective connectivity.

  Psychiatry research 20111130

• The amphetamine-chlordiazepoxide mixture, a pharmacological screen for mood stabilizers, does not enhance amphetamine-induced disruption of prepulse inhibition.

  Behavioural brain research 20111120

• The anticonvulsant response to valproate in kindled rats is correlated with its effect on neuronal firing in the substantia nigra pars reticulata: a new mechanism of pharmacoresistance.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20111109

• Comparative efficacy and acceptability of mood stabilizer and second generation antipsychotic monotherapy for acute mania--a systematic review and meta-analysis.

  Journal of affective disorders 20111101

• Evaluation of valproate effects on acylcarnitine in epileptic children by LC-MS/MS.

  Brain & development 20111101

• Antidepressants elevate GDNF expression and release from C₆ glioma cells in a β-arrestin1-dependent, CREB interactive pathway.

  The international journal of neuropsychopharmacology 20111101

• Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy.

  Breast cancer research and treatment 20111101

• Purmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the Hedgehog pathway.

  Stem cells and development 20111101

• A 5-aza-2'-deoxycytidine/valproate combination induces cytotoxic T-cell response against mesothelioma.

  The European respiratory journal 20111101

• Valproic acid-induced DNA damage increases embryonic p27(KIP1) and caspase-3 expression: a mechanism for valproic-acid induced neural tube defects.

  Reproductive toxicology (Elmsford, N.Y.) 20111101

• Infiltration of sodium valproate with compartment syndrome and bullous reaction: case report and literature review.

  Burns : journal of the International Society for Burn Injuries 20111101

• The neuroprotective effect of curcumin and Nigella sativa oil against oxidative stress in the pilocarpine model of epilepsy: a comparison with valproate.

  Neurochemical research 20111101

• Antiepileptic drug use during pregnancy: perinatal outcomes.

  Seizure 20111101

• Overexpression of the small GTPase Arl4D suppresses adipogenesis.

  International journal of molecular medicine 20111101

• Inhibition mechanism of carbapenem antibiotics on acylpeptide hydrolase, a key enzyme in the interaction with valproic acid.

  Xenobiotica; the fate of foreign compounds in biological systems 20111101

• Combined treatment with the mood stabilizers lithium and valproate produces multiple beneficial effects in transgenic mouse models of Huntington's disease.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20111101

• Efficacy of novel histone deacetylase inhibitor, AR42, in a mouse model of, human T-lymphotropic virus type 1 adult T cell lymphoma.

  Leukemia research 20111101

• Histone deacetylase inhibitor enhances the anti-tumor effect of gemcitabine: a special reference to gene-expression microarray analysis.

  Oncology reports 20111101

• Treating mouse models of Huntington disease.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20111101

• A meta-analysis of polycystic ovary syndrome in women taking valproate for epilepsy.

  Epilepsy research 20111101

• HDAC inhibition delays cell cycle progression of human bladder cancer cells in vitro.

  Anti-cancer drugs 20111101

• The effects of chronic treatment with mood stabilizers on the rat hippocampal post-synaptic density proteome.

  Journal of neurochemistry 20111101

• Retinoic acid influences neuronal migration from the ganglionic eminence to the cerebral cortex.

  Journal of neurochemistry 20111101

• Valproic acid increases susceptibility to endotoxin shock through enhanced release of high-mobility group box 1.

  Shock (Augusta, Ga.) 20111101

• Design and synthesis of 2-(1, 3-dioxoisoindolin-2-yl)-N-(4-oxo-2-substitutedthiazolidin-3-yl) acetamide derivatives as potential anticonvulsant agents.

  European journal of medicinal chemistry 20111101

• Design and pharmacological activity of glycinamide and N-methoxy amide derivatives of analogs and constitutional isomers of valproic acid.

  Epilepsy & behavior : E&B 20111101

• Synthesis and anticonvulsant activity of some new thiazolo[3,2-a][1,3]diazepine, benzo[d]thiazolo[5,2-a][12,6]diazepine and benzo[d]oxazolo[5,2-a][12,6]diazepine analogues.

  European journal of medicinal chemistry 20111101

• [Slow the pace of renal failure in autosomal dominant polycystic kidney disease: hopes and disappointments].

  Presse medicale (Paris, France : 1983) 20111101

• Use of antiepileptic medications in pregnancy in relation to risks of birth defects.

  Annals of epidemiology 20111101

• Comparative efficacy and safety of intravenous valproate and phenytoin in children.

  Pediatric neurology 20111101

• [Concussive convulsions: seizure or no seizure?].

  Fortschritte der Neurologie-Psychiatrie 20111101

• Differential expression of neuronal dopamine and serotonin transporters DAT and SERT in megakaryocytes and platelets generated from human MEG-01 megakaryoblasts.

  Cell and tissue research 20111101

• Valproate and lamotrigine in children and adolescents with drop attacks: follow-up after the first year.

  Epilepsia 20111101

• Gingival enlargement.

  Journal of the American Dental Association (1939) 20111101

• Sodium valproate - a rare cause of eosinophilic pleural effusion.

  Internal medicine journal 20111101

• [Lamotrigine add-on therapy for childhood-onset refractory epilepsy: comparison of the efficacy between 3 months and 6 months after initiation].

  No to hattatsu = Brain and development 20111101

• cAMP-dependent phosphorylation of microtubule-associated protein-2 during treatment of sodium valproate and audiogenic kindling.

  Bulletin of experimental biology and medicine 20111101

• Protective effects of valproic acid on the nigrostriatal dopamine system in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.

  Neuroscience 20111027

• Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemia-reperfusion injury.

  Neuroscience letters 20111024

• Pluripotency-related, valproic acid (VPA)-induced genome-wide histone H3 lysine 9 (H3K9) acetylation patterns in embryonic stem cells.

  The Journal of biological chemistry 20111014

• Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain-attenuating properties.

  Journal of medicinal chemistry 20111013

• Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.

  Journal of medicinal chemistry 20111013

• Valproic acid and sodium valproate for neuropathic pain and fibromyalgia in adults.

  The Cochrane database of systematic reviews 20111005

• Large amino acid transporter 1 (LAT1) prodrugs of valproic acid: new prodrug design ideas for central nervous system delivery.

  Molecular pharmaceutics 20111003

• Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules.

  Molecular carcinogenesis 20111001

• Predictability of individualized dosage regimens of carbamazepine and valproate mono- and combination therapy.

  Journal of clinical pharmacy and therapeutics 20111001

• Valproate-induced worsening of seizures: clue to underlying diagnosis.

  Journal of child neurology 20111001

• The retardation of myometrial infiltration, reduction of uterine contractility, and alleviation of generalized hyperalgesia in mice with induced adenomyosis by levo-tetrahydropalmatine (l-THP) and andrographolide.

  Reproductive sciences (Thousand Oaks, Calif.) 20111001

• Treatment of spinal muscular atrophy cells with drugs that upregulate SMN expression reveals inter- and intra-patient variability.

  European journal of human genetics : EJHG 20111001

• [Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications].

  Der Nervenarzt 20111001

• Efficacy and safety of adjunctive oral ziprasidone for acute treatment of depression in patients with bipolar I disorder: a randomized, double-blind, placebo-controlled trial.

  The Journal of clinical psychiatry 20111001

• Novel characterization of drug-associated pancreatitis in children.

  Journal of pediatric gastroenterology and nutrition 20111001

• The effect of topiramate monotherapy on bone mineral density and markers of bone and mineral metabolism in premenopausal women with epilepsy.

  Epilepsia 20111001

• Potential role for valproate in the treatment of high--risk brain tumors of childhood-results from a retrospective observational cohort study.

  Pediatric hematology and oncology 20111001

• Levetiracetam compared to valproic acid: plasma concentration levels, adverse effects and interactions in aneurysmal subarachnoid hemorrhage.

  Clinical neurology and neurosurgery 20111001

• Symptomatic response to divalproex in subtypes of conduct disorder.

  Child psychiatry and human development 20111001

• Treatment of suicide attempters with bipolar disorder: a randomized clinical trial comparing lithium and valproate in the prevention of suicidal behavior.

  The American journal of psychiatry 20111001

• Combined inhibition of DNA methyltransferase and histone deacetylase restores caspase-8 expression and sensitizes SCLC cells to TRAIL.

  Carcinogenesis 20111001

• Valproic acid induces monoamine oxidase A via Akt/forkhead box O1 activation.

  Molecular pharmacology 20111001

• [Acute valproic acid intoxication: interest of a treatment by extracoporeal elimination combined with L-carnitine].

  Annales francaises d'anesthesie et de reanimation 20111001

• Effects of neonatal treatment with valproic acid on vasopressin immunoreactivity and olfactory behaviour in mice.

  Journal of neuroendocrinology 20111001

• Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy.

  Pharmacogenetics and genomics 20111001

• Perioperative exacerbation of valproic acid-associated hyperammonemia: a clinical and genetic analysis.

  Anesthesia and analgesia 20111001

• Mesenchymal stem cells primed with valproate and lithium robustly migrate to infarcted regions and facilitate recovery in a stroke model.

  Stroke 20111001

• Valproic acid attenuates proteinuria and kidney injury.

  Journal of the American Society of Nephrology : JASN 20111001

• A pilot study of the efficacy and safety of paroxetine augmented with risperidone, valproate, buspirone, trazodone, or thyroid hormone in adult Chinese patients with treatment-resistant major depression.

  Journal of clinical psychopharmacology 20111001

• Carnitine supplementation for valproate-related hyperammonemia to maintain therapeutic valproate level.

  Journal of clinical psychopharmacology 20111001

• An UPLC-MS/MS method for the determination of valproic acid in blood of a fatal intoxication case.

  Journal of forensic and legal medicine 20111001

• Valproic acid intoxication with suicide attempt in a pediatric patient.

  Pediatrics international : official journal of the Japan Pediatric Society 20111001

• Successful reintroduction of valproic acid after the occurrence of pancytopenia.

  The American journal of geriatric pharmacotherapy 20111001

• Observational BALANCE.

  The British journal of psychiatry : the journal of mental science 20111001

• Acoustic startle hypersensitivity in Mceph mice and its effect on hippocampal excitability.

  The European journal of neuroscience 20111001

• Hard outcomes: clinical trials to reduce suicide.

  The American journal of psychiatry 20111001

• Valproate-induced hyperammonemia and seizures: perioperative concerns.

  Paediatric anaesthesia 20111001

• [Drug-induced tremor].

  Fortschritte der Neurologie-Psychiatrie 20111001

• Effects of adjunct valproic acid on clinical symptoms and saccadic eye movements in schizophrenia.

  Human psychopharmacology 20111001

• Fasting insulin and HOMA-index changes in patients treated with valproic acid.

  Georgian medical news 20111001

• [Effects of sodium valproate on neutrophils' oxidative metabolism and oxidant status in children with idiopathic epilepsy].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20111001

• Role of ZBP-89 in human globin gene regulation and erythroid differentiation.

  Blood 20110929

• Chronic divalproex sodium use and brain atrophy in Alzheimer disease.

  Neurology 20110927

• Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma.

  Neurology 20110920

• Valproic acid as the AED of choice for patients with glioblastoma? The jury is out.

  Neurology 20110920

• Synaptic and intrinsic balancing during postnatal development in rat pups exposed to valproic acid in utero.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20110914

• Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury.

  Neuroscience letters 20110908

• Valproic acid synergistically enhances the cytotoxicity of gossypol in DU145 prostate cancer cells: an iTRTAQ-based quantitative proteomic analysis.

  Journal of proteomics 20110906

• Amelioration of behavioral aberrations and oxidative markers by green tea extract in valproate induced autism in animals.

  Brain research 20110902

• Regulation of kidney development by histone deacetylases.

  Pediatric nephrology (Berlin, Germany) 20110901

• The teratogenic potencies of valproic acid derivatives and their effects on biological end-points are related to changes in histone deacetylase and Erk1/2 activities.

  Basic & clinical pharmacology & toxicology 20110901

• Wfs1 mutation makes mice sensitive to insulin-like effect of acute valproic acid and resistant to streptozocin.

  Journal of physiology and biochemistry 20110901

• Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes.

  Blood 20110901

• Valproate-induced Fanconi syndrome in a 27-year-old woman.

  Journal of general internal medicine 20110901

• Lack of association of ABCB1 haplotypes on five loci with response to treatment in epilepsy.

  Seizure 20110901

• Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.

  Clinical endocrinology 20110901

• Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.

  Pharmacology, biochemistry, and behavior 20110901

• Evidence for association of hyperprolinemia with schizophrenia and a measure of clinical outcome.

  Schizophrenia research 20110901

• HDAC inhibitors potentiate the apoptotic effect of enzastaurin in lymphoma cells.

  Apoptosis : an international journal on programmed cell death 20110901

• Application of the histone deacetylase inhibitors for the treatment of endometriosis: histone modifications as pathogenesis and novel therapeutic target.

  Human reproduction (Oxford, England) 20110901

• VPA-induced recurrent pancreatitis in a cystic fibrosis carrier.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20110901

• [Paroxysmal tonic upward gaze deviation triggered by valproic acid within the context of focal epilepsy].

  Revista de neurologia 20110901

• No interaction between valproate and meropenem in a cirrhotic patient.

  The Annals of pharmacotherapy 20110901

• Thyroid hormone levels in children receiving carbamazepine or valproate.

  Pediatric neurology 20110901

• Rare magnetic resonance imaging findings in medium-chain acyl-coenzyme A dehydrogenase deficiency.

  Pediatric neurology 20110901

• Detrimental effects of divalproex on warfarin therapy following mechanical valve replacement.

  Journal of cardiac surgery 20110901

• A fatal case of simultaneous ingestion of mirtazapine, escitalopram, and valproic acid.

  Journal of analytical toxicology 20110901

• The consequences of valproate overdose.

  Clinical chemistry 20110901

• Commentary.

  Clinical chemistry 20110901

• Commentary.

  Clinical chemistry 20110901

• [The optimal combination of ECT with pharmacotherapy].

  Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20110901

• Generalised spike-and-slow-wave complexes without seizures in schizophrenia.

  The British journal of psychiatry : the journal of mental science 20110901

• Short report: A calcified Taenia solium granuloma associated with recurrent perilesional edema causing refractory seizures: histopathological features.

  The American journal of tropical medicine and hygiene 20110901

• [Effects of valproate sodium on pituitary gonadotropin in adolescent girls with epilepsy].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20110901

• A case of hyperammonaemic encephalopathy due to valproic acid.

  The Netherlands journal of medicine 20110901

• Acute chorea caused by valproate in an elderly.

  Acta neurologica Belgica 20110901

• HDAC inhibitors sodium butyrate and sodium valproate do not affect human ncor1 and ncor2 gene expression in HL-60 cells.

  Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20110901

• Animal model of autism induced by prenatal exposure to valproate: behavioral changes and liver parameters.

  Brain research 20110823

• Valproic acid inhibits neurosphere formation by adult subventricular cells by a lithium-sensitive mechanism.

  Neuroscience letters 20110818

• Influencing clinical practice regarding the use of antiepileptic medications during pregnancy: modeling the potential impact on the prevalences of spina bifida and cleft palate in the United States.

  American journal of medical genetics. Part C, Seminars in medical genetics 20110815

• [Effects of magnesium valproate on endocrine system and reproductive functions of female epileptics].

  Zhonghua yi xue za zhi 20110809

• Quantification of SMN protein in leucocytes from spinal muscular atrophy patients: effects of treatment with valproic acid.

  Journal of neurology, neurosurgery, and psychiatry 20110801

• Development of a transgenic zebrafish model expressing GFP in the notochord, somite and liver directed by the hfe2 gene promoter.

  Transgenic research 20110801

• New insights on the mechanisms of valproate-induced hyperammonemia: inhibition of hepatic N-acetylglutamate synthase activity by valproyl-CoA.

  Journal of hepatology 20110801

• Cerebellar atrophy in a child with valproate toxicity.

  Indian journal of pediatrics 20110801

• Synergistic effect of bortezomib and valproic acid treatment on the proliferation and apoptosis of acute myeloid leukemia and myelodysplastic syndrome cells.

  Annals of hematology 20110801

• Hematologic improvement and response in elderly AML/RAEB patients treated with valproic acid and low-dose Ara-C.

  Leukemia research 20110801

• Valproic acid and warfarin: an underrecognized drug interaction.

  Neurocritical care 20110801

• The mood stabilizer valproic acid induces proliferation and myelination of rat Schwann cells.

  Neuroscience research 20110801

• An inexpensive way to treat elderly patients with high-risk MDS or AML.

  Leukemia research 20110801

• [Virological aspects of HTLV-1 infection and new therapeutical concepts].

  Bulletin de la Societe de pathologie exotique (1990) 20110801

• Are post intracerebral hemorrhage seizures prevented by anti-epileptic treatment?

  Epilepsy research 20110801

• Hypermetabolism in the left thalamus and right inferior temporal area on positron emission tomography-statistical parametric mapping (PET-SPM) in a patient with Charles Bonnet syndrome resolving after treatment with valproic acid.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110801

• Hyperammonemic encephalopathy related to valproate, phenobarbital, and topiramate synergism.

  Epilepsy & behavior : E&B 20110801

• Valproate associated diffuse alveolar hemorrhage.

  European journal of neurology 20110801

• Pharmacologic treatments for pediatric bipolar disorder: a review and meta-analysis.

  Journal of the American Academy of Child and Adolescent Psychiatry 20110801

• Association of genetic variants in six candidate genes with valproic acid therapy optimization.

  Pharmacogenomics 20110801

• Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease.

  Archives of general psychiatry 20110801

• Image in toxicology: Pseudo-subarachnoid hemorrhage in a case of severe valproic acid poisoning.

  Clinical toxicology (Philadelphia, Pa.) 20110801

• Inhibitory effects of valproate on impairment of Y-maze alternation behavior induced by repeated electroconvulsive seizures and c-Fos protein levels in rat brains.

  Acta medica Okayama 20110801

• [The effects of administration of valproic acid on organ function and outcome in a canine lethal hemorrhagic shock model].

  Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20110801

• Authors’ response.

  The British journal of ophthalmology 20110801

• Valproic acid inhibits prostate cancer cell migration by up-regulating E-cadherin expression.

  Die Pharmazie 20110801

• [Pharmacogenetics focused on special phenotypes].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110801

• Epigenetic treatment of neurological disease.

  Epigenomics 20110801

• Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder: fMRI outcomes.

  Psychiatry research 20110730

• Serum asymmetric dimethylarginine (ADMA), homocysteine, vitamin B(12), folate levels, and lipid profiles in epileptic children treated with valproic acid.

  European journal of pediatrics 20110701

• Re: Modulation of human motor cortex excitability by valproate.

  Psychopharmacology 20110701

• The mental retardation associated protein, srGAP3 negatively regulates VPA-induced neuronal differentiation of Neuro2A cells.

  Cellular and molecular neurobiology 20110701

• Risk factors for late-onset seizures related to cerebral contusions in adults with a moderate traumatic brain injury.

  Clinical neurology and neurosurgery 20110701

• Valproate treatment after liver transplant in a patient with Lennox-Gastaut syndrome.

  Seizure 20110701

• Acetylome and phosphoproteome modifications in imatinib resistant chronic myeloid leukaemia cells treated with valproic acid.

  Leukemia research 20110701

• Neurodevelopment of children exposed in utero to lamotrigine, sodium valproate and carbamazepine.

  Archives of disease in childhood 20110701

• Role of isovaleryl-CoA dehydrogenase and short branched-chain acyl-CoA dehydrogenase in the metabolism of valproic acid: implications for the branched-chain amino acid oxidation pathway.

  Drug metabolism and disposition: the biological fate of chemicals 20110701

• Medically intractable temporal lobe epilepsy in patients with normal MRI: surgical outcome in twenty-one consecutive patients.

  Seizure 20110701

• Reversible dementia and gait disturbance after prolonged use of valproic acid.

  Seizure 20110701

• Hippocampal sclerosis and ipsilateral headache among mesial temporal lobe epilepsy patients.

  Seizure 20110701

• Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus.

  Seizure 20110701

• Second-line status epilepticus treatment: comparison of phenytoin, valproate, and levetiracetam.

  Epilepsia 20110701

• Valproate reduces spontaneous generalized spikes and waves but not photoparoxysmal reactions in patients with idiopathic generalized epilepsies.

  Epilepsia 20110701

• Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells.

  International journal of oncology 20110701

• Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes.

  Naunyn-Schmiedeberg's archives of pharmacology 20110701

• Synthesis and anticonvulsant activity of 7-phenyl-6,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-ones and their derivatives.

  European journal of medicinal chemistry 20110701

• Valproate v. lithium in the treatment of bipolar disorder in clinical practice: observational nationwide register-based cohort study.

  The British journal of psychiatry : the journal of mental science 20110701

• Epigenetic, polymorphic and mutational (Αα167Arg→Lys) contribution to a functionally abnormal fibrinogen.

  Journal of thrombosis and haemostasis : JTH 20110701

• No effect of co-administered antiepileptic drugs on in-vivo protein binding parameters of valproic acid in patients with epilepsy.

  The Journal of pharmacy and pharmacology 20110701

• Valproic acid alleviates generalized hyperalgesia in mice with induced adenomyosis.

  The journal of obstetrics and gynaecology research 20110701

• Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.

  The Lancet. Neurology 20110701

• Identifying an uptake mechanism for the antiepileptic and bipolar disorder treatment valproic acid using the simple biomedical model Dictyostelium.

  Journal of cell science 20110701

• LC-MS/MS method for simultaneous determination of valproic acid and major metabolites in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110701

• Lovastatin and valproic acid additively attenuate cell invasion in ACC-MESO-1 cells.

  Biochemical and biophysical research communications 20110701

• Clinical and pharmacy utilization outcomes with brand to generic antiepileptic switches in patients with epilepsy.

  Epilepsia 20110701

• Long-term control of epileptic drop attacks with the combination of valproate, lamotrigine, and a benzodiazepine: a 'proof of concept,' open label study.

  Epilepsia 20110701

• Valproate release from polycaprolactone implants prepared by 3D-bioplotting.

  Die Pharmazie 20110701

• Sodium valproate induces mitochondria-dependent apoptosis in human hepatoblastoma cells.

  Chinese medical journal 20110701

• [Inhibitory effect of valproic acid on xenografted Kasumi-1 tumor growth in nude mouse and its mechanism].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110701

• Malformation of the superior olivary complex in an animal model of autism.

  Brain research 20110629

• Inhibitors of histone deacetylases: correlation between isoform specificity and reactivation of HIV type 1 (HIV-1) from latently infected cells.

  The Journal of biological chemistry 20110624

• Valproic acid induces apoptosis in differentiating hippocampal neurons by the release of tumor necrosis factor-α from activated astrocytes.

  Neuroscience letters 20110622

• Valproic acid improves outcome after rodent spinal cord injury: potential roles of histone deacetylase inhibition.

  Brain research 20110617

• Intrinsic anticancer drug resistance of malignant melanoma cells is abrogated by IFN-β and valproic acid.

  Cancer research 20110615

• [Meropenem decreases valproate plasmatic concentrations].

  Medicina clinica 20110611

• Is anticonvulsant treatment of mania a class effect? Data from randomized clinical trials.

  CNS neuroscience & therapeutics 20110601

• Evaluation of the subjective and reinforcing effects of diphenhydramine, levetiracetam, and valproic acid.

  Journal of psychopharmacology (Oxford, England) 20110601

• [Valproate-induced hyperammonemic encephalopathy].

  La Revue de medecine interne 20110601

• Acute efficacy of divalproex sodium versus placebo in mood stabilizer-naive bipolar I or II depression: a double-blind, randomized, placebo-controlled trial.

  The Journal of clinical psychiatry 20110601

• Improvement in verbal memory after withdrawal of carbamazepine and valproate in patients with well-controlled epilepsy: a randomized, double-blind study.

  Acta neurologica Scandinavica 20110601

• Further characterization of the predictive validity of the Brattleboro rat model for antipsychotic efficacy.

  Journal of psychopharmacology (Oxford, England) 20110601

• A cyclic AMP analog, 8-Br-cAMP, enhances the induction of pluripotency in human fibroblast cells.

  Stem cell reviews 20110601

• A mesenchymal stromal cell line resistant to paclitaxel that spontaneously differentiates into osteoblast-like cells.

  Cell biology and toxicology 20110601

• Study of epileptiform activity in cerebral ganglion of mud crab Scylla serrata.

  Invertebrate neuroscience : IN 20110601

• Lack of association of ABCB1 and PXR polymorphisms with response to treatment in epilepsy.

  Seizure 20110601

• Neuroanatomical profile of antimaniac effects of histone deacetylases inhibitors.

  Molecular neurobiology 20110601

• Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells.

  Toxicological sciences : an official journal of the Society of Toxicology 20110601

• Effect of the enucleation procedure on the reprogramming potential and developmental capacity of mouse cloned embryos treated with valproic acid.

  Reproduction (Cambridge, England) 20110601

• Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells.

  Clinical & experimental metastasis 20110601

• Morphological abnormalities of embryonic cranial nerves after in utero exposure to valproic acid: implications for the pathogenesis of autism with multiple developmental anomalies.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20110601

• Valproate for the treatment of medication-induced impulse-control disorders in three patients with Parkinson's disease.

  Parkinsonism & related disorders 20110601

• Are antiepileptic drugs used in the treatment of migraine associated with an increased risk of suicidality?

  Current pain and headache reports 20110601

• Novel trans-platinum complexes of the histone deacetylase inhibitor valproic acid; synthesis, in vitro cytotoxicity and mutagenicity.

  Journal of inorganic biochemistry 20110601

• Intermittent drug dosing intervals guided by the operational multiple dosing half lives for predictable plasma accumulation and fluctuation.

  Journal of pharmacokinetics and pharmacodynamics 20110601

• The effects of valproic acid and levetiracetam on chicken embryos.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110601

• Effects of valproic acid on organic acid metabolism in children: a metabolic profiling study.

  Clinical pharmacology and therapeutics 20110601

• Reversible parkinsonism and cognitive decline due to a possible interaction of valproic acid and quetiapine.

  Journal of clinical pharmacy and therapeutics 20110601

• The relationship between UGT1A4 polymorphism and serum concentration of lamotrigine in patients with epilepsy.

  Epilepsy research 20110601

• Histone deacetylase inhibitor valproic acid sensitizes B16F10 melanoma cells to cucurbitacin B treatment.

  Acta biochimica et biophysica Sinica 20110601

• A pilot phase II study of valproic acid for treatment of low-grade neuroendocrine carcinoma.

  The oncologist 20110601

• New adipocytokines (vaspin, apelin, visfatin, adiponectin) levels in children treated with valproic acid.

  European cytokine network 20110601

• Transcriptional activation of human GM3 synthase (hST3Gal V) gene by valproic acid in ARPE-19 human retinal pigment epithelial cells.

  BMB reports 20110601

• Fractures and Fanconi syndrome due to prolonged sodium valproate use.

  Neuropediatrics 20110601

• Combined valproic acid and celecoxib treatment induced synergistic cytotoxicity and apoptosis in neuroblastoma cells.

  Anticancer research 20110601

• [Observation on therapeutic effect of acupoint catgut-embedding combined western medicine for epilepsy of generalized seizures type].

  Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20110601

• Neuroendocrine plasticity in GnRH release is disrupted by valproic acid treatment of cycling rats.

  Acta neurologica Belgica 20110601

• Dilemmas in diagnostics and therapy of rolandic epilepsy.

  Vojnosanitetski pregled 20110601

• Rare but real--the effects of sodium valproate in pregnancy.

  Irish medical journal 20110601

• Microinjection of valproic acid into the ventrolateral orbital cortex exerts an antidepressant-like effect in the rat forced swim test.

  Brain research bulletin 20110530

• Valproate reduces tau phosphorylation via cyclin-dependent kinase 5 and glycogen synthase kinase 3 signaling pathways.

  Brain research bulletin 20110530

• Final results from 18 years of the International Lamotrigine Pregnancy Registry.

  Neurology 20110524

• Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer.

  The Prostate 20110515

• Suppression of histone deacetylases worsens right ventricular dysfunction after pulmonary artery banding in rats.

  American journal of respiratory and critical care medicine 20110515

• Real-time, in vivo monitoring and pharmacokinetics of valproic acid via a novel biomarker in exhaled breath.

  Chemical communications (Cambridge, England) 20110507

• Weight gain following treatment with valproic acid: pathogenetic mechanisms and clinical implications.

  Obesity reviews : an official journal of the International Association for the Study of Obesity 20110501

• Potency ranking of valproic acid analogues as to inhibition of cardiac differentiation of embryonic stem cells in comparison to their in vivo embryotoxicity.

  Reproductive toxicology (Elmsford, N.Y.) 20110501

• Lack of scientific rationale for use of valproic acid for retinitis pigmentosa.

  The British journal of ophthalmology 20110501

• Modulation of human motor cortex excitability by valproate.

  Psychopharmacology 20110501

• Valproic acid-associated acute liver failure in children: case report and analysis of liver transplantation outcomes in the United States.

  The Journal of pediatrics 20110501

• A preliminary investigation on the possible association between diminished copper availability and non-alcoholic fatty liver disease in epileptic patients treated with valproic acid.

  Upsala journal of medical sciences 20110501

• Effect of valproate, lamotrigine and levetiracetam on excitability and firing properties of CA1 neurons in rat brain slices.

  Cellular and molecular neurobiology 20110501

• Progressive encephalopathy with cerebral oedema and infarctions associated with valproate and diazepam overdose.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20110501

• Encapsulation of valproate-loaded hydrogel nanoparticles in intact human erythrocytes: a novel nano-cell composite for drug delivery.

  Journal of pharmaceutical sciences 20110501

• Glutathione depletion by valproic acid in sandwich-cultured rat hepatocytes: Role of biotransformation and temporal relationship with onset of toxicity.

  Toxicology and applied pharmacology 20110501

• D-cycloserine facilitates procedural learning but not declarative learning in healthy humans: a randomized controlled trial of the effect of D-cycloserine and valproic acid on overnight properties in the performance of non-emotional memory tasks.

  Neurobiology of learning and memory 20110501

• The effect of valproate therapy on thrombin generation determined by calibrated automated thrombography.

  Klinische Padiatrie 20110501

• Have advances in extracorporeal removal techniques changed the indications for their use in poisonings?

  Advances in chronic kidney disease 20110501

• Periodic catatonia.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20110501

• Treatment of taunting behavior in vascular dementia with valproic acid.

  Journal of the American Geriatrics Society 20110501

• [Hypo- and hypernatremia].

  Deutsche medizinische Wochenschrift (1946) 20110501

• [Three cases of Fanconi syndrome associated with valproate sodium treatment].

  No to hattatsu = Brain and development 20110501

• Valproic Acid related metabolic syndrome in patients with epilepsy.

  Georgian medical news 20110501

• Alternative fluids for prehospital resuscitation: 'pharmacological' resuscitation fluids.

  The Journal of trauma 20110501

• A rare occurrence of isolated neutropenia with valproic acid: a case report.

  Journal of the Indian Medical Association 20110501

• Chromatin-modifying agents promote the ex vivo production of functional human erythroid progenitor cells.

  Blood 20110428

• Effect of the histone deacetylase inhibitors on behavioural sensitization to a single morphine exposure in mice.

  Neuroscience letters 20110425

• Intravenous sodium valproate aborts migraine headaches rapidly.

  Acta neurologica Scandinavica 20110401

• Hydralazine and magnesium valproate as epigenetic treatment for myelodysplastic syndrome. Preliminary results of a phase-II trial.

  Annals of hematology 20110401

• Oxcarbazepine does not suppress cortical spreading depression.

  Cephalalgia : an international journal of headache 20110401

• The G1 phase arrest and apoptosis by intrinsic pathway induced by valproic acid inhibit proliferation of BGC-823 gastric carcinoma cells.

  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110401

• Comparison of the retention rates between carbamazepine and valproate as an initial monotherapy in Chinese patients with partial seizures: A ten-year follow-up, observational study.

  Seizure 20110401

• Effects of chronic treatment with valproate and oxcarbazepine on testicular development in rats.

  Seizure 20110401

• Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors.

  Surgery 20110401

• The embryonic stem cell test as tool to assess structure-dependent teratogenicity: the case of valproic acid.

  Toxicological sciences : an official journal of the Society of Toxicology 20110401

• Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice.

  Pharmacology, biochemistry, and behavior 20110401

• Magnesium valproate in learning disabled children with interictal paroxysmal EEG patterns: Preliminary report.

  Neuroscience letters 20110401

• Low-dose valproic acid enhances radiosensitivity of prostate cancer through acetylated p53-dependent modulation of mitochondrial membrane potential and apoptosis.

  Molecular cancer research : MCR 20110401

• Comparison of potency between histone deacetylase inhibitors trichostatin A and valproic acid on enhancing in vitro development of porcine somatic cell nuclear transfer embryos.

  In vitro cellular & developmental biology. Animal 20110401

• Rapid development of severe hypertriglyceridemia and hypercholesterolemia during augmentation of quetiapine with valproic acid.

  Journal of clinical psychopharmacology 20110401

• Paliperidone-associated seizure after discontinuation of sodium valproate: a case report.

  Journal of clinical psychopharmacology 20110401

• Serum concentrations of rufinamide in children and adults with epilepsy: the influence of dose, age, and comedication.

  Therapeutic drug monitoring 20110401

• Increase in non-transferrin bound iron and the oxidative stress status in epilepsy patients treated using valproic acid monotherapy.

  International journal of clinical pharmacology and therapeutics 20110401

• Adherence to guidelines by French psychiatrists in their real world of clinical practice.

  The Journal of nervous and mental disease 20110401

• Topiramate vs divalproex sodium in the preventive treatment of migraine: a prospective 'real-world' study.

  Headache 20110401

• Basilar-type migraine with coma: case reports and literature review.

  Pain medicine (Malden, Mass.) 20110401

• Pediatric drug induced hypersensitivity syndrome: case report.

  Georgian medical news 20110401

• [Rational combinations of antiepileptic drugs for refractory epilepsy].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110401

• [Suppressive effect of valproic acid on fear conditioning induced by dopamine in the amygdala: Its verification using the microdialysis].

  Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20110401

• Valproate reduces CHOP levels and preserves oligodendrocytes and axons after spinal cord injury.

  Neuroscience 20110331

• [Chronic migraine: not well known but not rare!].

  MMW Fortschritte der Medizin 20110324

• Study of the structural and electronic properties of valproic acid and new derivatives used as anticonvulsant agents.

  The journal of physical chemistry. A 20110310

• [Valproate and pregnancy].

  Ugeskrift for laeger 20110307

• The critical period of valproate exposure to induce autistic symptoms in Sprague-Dawley rats.

  Toxicology letters 20110305

• Molecular biology: The expanding arena of DNA repair.

  Nature 20110303

• HDACs link the DNA damage response, processing of double-strand breaks and autophagy.

  Nature 20110303

• Pharmacokinetics and clinical application of intravenous valproate in Thai epileptic children.

  Brain & development 20110301

• [Psychotic disorder revealing epilepsy linked to a dysembryoma of the left hippocampus].

  Revue neurologique 20110301

• Short-term exposure of umbilical cord blood CD34+ cells to granulocyte-macrophage colony-stimulating factor early in culture improves ex vivo expansion of neutrophils.

  Cytotherapy 20110301

• Paliperidone extended-release as adjunctive therapy to lithium or valproate in the treatment of acute mania: a randomized, placebo-controlled study.

  Journal of affective disorders 20110301

• Drug-to-drug interaction between sodium valproate and trihexyphenidyl in a child with extrapyramidal cerebral palsy and epilepsy.

  European journal of clinical pharmacology 20110301

• Use of mood stabilizers for hospitalized psychotic and bipolar disorder patients.

  International clinical psychopharmacology 20110301

• Effects of epilepsy and antiepileptic drugs on nitric oxide, lipid peroxidation and xanthine oxidase system in children with idiopathic epilepsy.

  Seizure 20110301

• Valproate uncompetitively inhibits arachidonic acid acylation by rat acyl-CoA synthetase 4: relevance to valproate's efficacy against bipolar disorder.

  Biochimica et biophysica acta 20110301

• Early valproic acid exposure alters functional organization in the primary visual cortex.

  Experimental neurology 20110301

• Valproic acid suppresses interleukin-1ß-induced microsomal prostaglandin E2 synthase-1 expression in chondrocytes through upregulation of NAB1.

  The Journal of rheumatology 20110301

• Severe fetal valproate syndrome: combination of complex cardiac defect, multicystic dysplastic kidney, and trigonocephaly.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20110301

• High unbound fraction of valproic acid in a hypoalbuminemic critically ill patient on renal replacement therapy.

  The Annals of pharmacotherapy 20110301

• Enhancement of temozolomide-induced apoptosis by valproic acid in human glioma cell lines through redox regulation.

  Journal of molecular medicine (Berlin, Germany) 20110301

• [Expressive language disorder and focal paroxysmal activity].

  Revista de neurologia 20110301

• Association between ABCB1 polymorphism and response to sodium valproate treatment in Malaysian epilepsy patients.

  Epileptic disorders : international epilepsy journal with videotape 20110301

• A case of polyglandular autoimmune syndrome type I with unusual presentation.

  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20110301

• Efficacy of aripiprazole adjunctive to lithium or valproate in the long-term treatment of patients with bipolar I disorder with an inadequate response to lithium or valproate monotherapy: a multicenter, double-blind, randomized study.

  Bipolar disorders 20110301

• Bipolar disorder presenting as stalking--a case report.

  Psychiatria Danubina 20110301

• Symptoms of agitated depression and/or akathisia.

  Psychiatria Danubina 20110301

• [Prolonged convulsion after intoxication of alachlor herbicide (Lasso): a case report].

  Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20110301

• [The efficacy and safety of valproic acid in combination with low dose chemotherapy on intermediate and high-risk myelodysplastic syndrome].

  Zhonghua nei ke za zhi 20110301

• Hemostatic and pharmacologic resuscitation: results of a long-term survival study in a swine polytrauma model.

  The Journal of trauma 20110301

• A critical time window for the survival of neural progenitor cells by HDAC inhibitors in the hippocampus.

  Molecules and cells 20110227

• Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001.

  Life sciences 20110227

• Habenula volume in bipolar disorder and major depressive disorder: a high-resolution magnetic resonance imaging study.

  Biological psychiatry 20110215

• Valproic acid perturbs hematopoietic homeostasis by inhibition of erythroid differentiation and activation of the myelo-monocytic pathway.

  Biochemical pharmacology 20110215

• Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: a possible cause of valproic acid-induced osteomalacia?

  Toxicology letters 20110205

• Childhood absence epilepsy: Elctroclinical features and diagnostic criteria.

  Brain & development 20110201

• Downregulation of survivin and aurora A by histone deacetylase and RAS inhibitors: a new drug combination for cancer therapy.

  International journal of cancer 20110201

• Early symptom change and prediction of subsequent remission with olanzapine augmentation in divalproex-resistant bipolar mixed episodes.

  Journal of psychiatric research 20110201

• Clinical correlates of low serum carnitine levels in hospitalized psychiatric patients.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20110201

• Lithium and valproate modulate antioxidant enzymes and prevent ouabain-induced oxidative damage in an animal model of mania.

  Journal of psychiatric research 20110201

• [Seizure aggravation by valproate in primary generalized epilepsy].

  Der Nervenarzt 20110201

• Retrospective analysis of the effectiveness of first-line antiepileptic drugs for generalized onset and unclassified epileptic seizures in Chinese children.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110201

• Valproic acid alters mitochondrial cholesterol transport in Y1 adrenocortical cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20110201

• Migraine preventive drugs differentially affect cortical spreading depression in rat.

  Neurobiology of disease 20110201

• Rise in brain GABA to further stress the metabolic link between valproate and creatine.

  Molecular genetics and metabolism 20110201

• Synergistic induction of PI-PLCβ1 signaling by azacitidine and valproic acid in high-risk myelodysplastic syndromes.

  Leukemia 20110201

• Phase 1 study of valproic acid in pediatric patients with refractory solid or CNS tumors: a children's oncology group report.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20110201

• Transcriptional changes induced by epigenetic therapy with hydralazine and magnesium valproate in cervical carcinoma.

  Oncology reports 20110201

• Status epilepticus.

  Indian journal of pediatrics 20110201

• Design & synthesis of N'-[substituted] pyridine-4-carbohydrazides as potential anticonvulsant agents.

  European journal of medicinal chemistry 20110201

• Valproate decreases frequency facilitation at mossy fiber--CA3 synapses after status epilepticus.

  Epilepsy research 20110201

• Pharmacological treatment of behavioural and psychological symptoms of dementia in psychogeriatric inpatient units.

  Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20110201

• The impact of dosage of sustained-release formulation on valproate clearance and plasma concentration in psychiatric patients: analysis based on routine therapeutic drug monitoring data.

  Journal of clinical psychopharmacology 20110201

• Long term outcome in children affected by absence epilepsy with onset before the age of three years.

  Epilepsy & behavior : E&B 20110201

• Pharmacological induction of neuroglobin expression.

  Pharmacology 20110201

• Anticonvulsant activity of BmK AS, a sodium channel site 4-specific modulator.

  Epilepsy & behavior : E&B 20110201

• Potential interaction between valproic acid and doripenem.

  Current drug safety 20110201

• The effect of lamotrigine on valproic acid concentrations.

  Current drug safety 20110201

• Valproate attenuates the risk of myocardial infarction in patients with epilepsy: a nationwide cohort study.

  Pharmacoepidemiology and drug safety 20110201

• Nonalcoholic fatty liver disease in adolescents receiving valproic acid.

  Epilepsy & behavior : E&B 20110201

• Levels of miR-29b do not predict for response in patients with acute myelogenous leukemia treated with the combination of 5-azacytidine, valproic acid, and ATRA.

  American journal of hematology 20110201

• Valproate prescription prevalence among women of childbearing age.

  Psychiatric services (Washington, D.C.) 20110201

• Effect of histone deacetylase inhibitor in combination with 5-fluorouracil on pancreas cancer and cholangiocarcinoma cell lines.

  The journal of medical investigation : JMI 20110201

• Child development following in utero exposure: levetiracetam vs sodium valproate.

  Neurology 20110125

• [Treatment of bipolar disorder during pregnancy and in the postpartum period].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110121

• Oxidative stress in children affected by epileptic encephalopathies.

  Journal of the neurological sciences 20110115

• Imidazolylchromanone oxime ethers as potential anticonvulsant agents: Anticonvulsive evaluation in PTZ-kindling model of epilepsy and SAR study.

  Bioorganic & medicinal chemistry letters 20110115

• Thalamofrontal neurodevelopment in new-onset pediatric idiopathic generalized epilepsy.

  Neurology 20110104

• The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin.

  Cancer chemotherapy and pharmacology 20110101

• BsmI vitamin D receptor's polymorphism and bone mineral density in men and premenopausal women on long-term antiepileptic therapy.

  European journal of neurology 20110101

• Characterization, using comparative proteomics, of differentially expressed proteins in the hippocampus of the mesial temporal lobe of epileptic rats following treatment with valproate.

  Amino acids 20110101

• Valproate-doxorubicin: promising therapy for progressing mesothelioma. A phase II study.

  The European respiratory journal 20110101

• Therapeutic potential of valproic acid for retinitis pigmentosa.

  The British journal of ophthalmology 20110101

• Histone deacetylase regulates high mobility group A2-targeting microRNAs in human cord blood-derived multipotent stem cell aging.

  Cellular and molecular life sciences : CMLS 20110101

• Cluster headache associated with a sixth nerve palsy: a case report.

  Cephalalgia : an international journal of headache 20110101

• Valproic acid induces microglial dysfunction, not apoptosis, in human glial cultures.

  Neurobiology of disease 20110101

• Child Mania Rating Scale-Parent Version: a valid measure of symptom change due to pharmacotherapy.

  Journal of affective disorders 20110101

• Levo-tetrahydropalmatine retards the growth of ectopic endometrial implants and alleviates generalized hyperalgesia in experimentally induced endometriosis in rats.

  Reproductive sciences (Thousand Oaks, Calif.) 20110101

• Association of anxiolytic drugs diazepam and lorazepam, and the antiepileptic valproate, with heart defects--effects on cardiomyocytes in micromass (MM) and embryonic stem cell culture.

  Reproductive toxicology (Elmsford, N.Y.) 20110101

• Blood ammonia levels in epileptic children on 2 dose ranges of valproic acid monotherapy: a cross-sectional study.

  Journal of child neurology 20110101

• A 6-month prospective study on efficacy safety and QOL profiles of extended-release formulation of valproate in patients with epilepsy.

  Seizure 20110101

• Sodium valproate and highly active antiretroviral therapy in HIV positive patients who develop new onset seizures.

  Seizure 20110101

• The conclusions of Clemson et al concerning valproic acid are premature.

  The British journal of ophthalmology 20110101

• Protocols and applications of cellular metabolomics in safety studies using precision-cut tissue slices and carbon 13 NMR.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Valproic acid attenuates blood-brain barrier disruption in a rat model of transient focal cerebral ischemia: the roles of HDAC and MMP-9 inhibition.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110101

• Circulating levels of allopregnanolone, a neuroactive steroid, and leptin during treatment with valproic acid in children with epilepsy.

  Neuroendocrinology 20110101

• Does valproic acid induce neuroendocrine differentiation in prostate cancer?

  Journal of biomedicine & biotechnology 20110101

• Secretion of MIP-1β and MIP-1α by CD8(+) T-lymphocytes correlates with HIV-1 inhibition independent of coreceptor usage.

  Cellular immunology 20110101

• Epigenetic modulation of gene expression of human leukemia cell lines - induction of cell death and senescence.

  Neoplasma 20110101

• The Australian brain and cognition and antiepileptic drugs study: IQ in school-aged children exposed to sodium valproate and polytherapy.

  Journal of the International Neuropsychological Society : JINS 20110101

• Fluctuating and constant valproate administration gives equivalent seizure control in rats with genetic and acquired epilepsy.

  Seizure 20110101

• Antiplatelet activity of valproic acid contributes to decreased soluble CD40 ligand production in HIV type 1-infected individuals.

  Journal of immunology (Baltimore, Md. : 1950) 20110101

• Novel and emerging drugs for acute myeloid leukemia: pharmacology and therapeutic activity.

  Current medicinal chemistry 20110101

• Empirical approach for improved estimation of unbound serum concentrations of valproic acid in epileptic infants by considering their physical development.

  Biological & pharmaceutical bulletin 20110101

• 22q11.2 deletion presenting with severe hypocalcaemia, seizure and basal ganglia calcification in an adult man.

  Internal medicine journal 20110101

• Valproate-induced encephalopathy related to concurrent antimanic medications.

  The Journal of neuropsychiatry and clinical neurosciences 20110101

• Histone deacetylase inhibitors sodium butyrate and valproic acid delay spontaneous cell death in purified rat retinal ganglion cells.

  Molecular vision 20110101

• Carbamazepine and valproate as adjuncts in the treatment of alcohol withdrawal syndrome: a retrospective cohort study.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20110101

• The real mechanism of VPA-induced hyperammonemia remains unknown.

  General hospital psychiatry 20110101

• Psychogenic polydipsia in bipolar affective disorder--a case report.

  General hospital psychiatry 20110101

• [Aggravation of epilepsy by valproate sodium in a child with cryptogenic localization-related epilepsy].

  No to hattatsu = Brain and development 20110101

• Evaluation of muscle strength and motor abilities in children with type II and III spinal muscle atrophy treated with valproic acid.

  BMC neurology 20110101

• Magnesium sulfate and sodium valproate block methylphenidate-induced hyperlocomotion, an animal model of mania.

  Pharmacological reports : PR 20110101

• Effects of carbamazepine and metabolites on IL-2, IL-5, IL-6, IL-10 and IFN-γ secretion in epileptic patients: the influence of co-medication.

  Pharmacological reports : PR 20110101

• [Staring episodes in children with developmental disorders: epilepsy or behaviour?].

  Nederlands tijdschrift voor geneeskunde 20110101

• Folie à deux: double case-report of shared delusions with a fatal outcome.

  La Clinica terapeutica 20110101

• Drug-resistant epilepsia and fulminant valproate liver toxicity. Alpers-Huttenlocher syndrome in two children confirmed post mortem by identification of p.W748S mutation in POLG gene.

  Medical science monitor : international medical journal of experimental and clinical research 20110101

• Valproic acid exhibits biphasic effects on apoptotic cell death of activated lymphocytes through differential modulation of multiple signaling pathways.

  Journal of immunotoxicology 20110101

• [Relationship between plasma concentrations of valproic acid and hepatotoxicity in patients receiving high doses].

  Revue neurologique 20110101

• Brain delivery of valproic acid via intranasal administration of nanostructured lipid carriers: in vivo pharmacodynamic studies using rat electroshock model.

  International journal of nanomedicine 20110101

• Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer.

  Journal of hematology & oncology 20110101

• Estimation of resource utilisation difference between lithium and valproate treatment groups from the VALID study.

  Journal of medical economics 20110101

• Valproate inhibits GnRH-induced gonadotropin release from anterior pituitary cells of male rat in vitro.

  Neuro endocrinology letters 20110101

• Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons.

  PloS one 20110101

• Eicosapentaenoic acid ablates valproate-induced liver oxidative stress and cellular derangement without altering its clearance rate: dynamic synergy and therapeutic utility.

  Biochimica et biophysica acta 20110101

• Effective treatment with clozapine and valproate for refractory schizophrenia-like psychosis after cerebellar hemorrhage.

  Clinical neuropharmacology 20110101

• Decreased thyroid function in Korean women with bipolar disorder receiving valproic acid.

  General hospital psychiatry 20110101

• Serum insulin, cortisol, leptin, neuropeptide Y, galanin and ghrelin levels in epileptic children receiving valproate.

  Hormone research in paediatrics 20110101

• Apoptotic cell death in the fission yeast Schizosaccharomyces pombe induced by valproic acid and its extreme susceptibility to pH change.

  Bioscience, biotechnology, and biochemistry 20110101

• Absence seizure in the elderly.

  Annals of African medicine 20110101

• Valproic acid inhibits human hepatocellular cancer cells growth in vitro and in vivo.

  Journal of experimental therapeutics & oncology 20110101

• Haematological side effects of antiepileptic drug treatment in patients with epilepsy.

  Acta neurologica Scandinavica. Supplementum 20110101

• Valproic acid inhibits neural progenitor cell death by activation of NF-κB signaling pathway and up-regulation of Bcl-XL.

  Journal of biomedical science 20110101

• Therapeutic window of opportunity for the neuroprotective effect of valproate versus the competitive AMPA receptor antagonist NS1209 following status epilepticus in rats.

  Neuropharmacology 20110101

• Antiepileptic drugs with mood stabilizing properties and their relation with psychotropic drug use in institutionalized epilepsy patients with intellectual disability.

  Research in developmental disabilities 20110101

• SMA CARNIVAL TRIAL PART II: a prospective, single-armed trial of L-carnitine and valproic acid in ambulatory children with spinal muscular atrophy.

  PloS one 20110101

• Rearing conditions differentially affect the locomotor behavior of larval zebrafish, but not their response to valproate-induced developmental neurotoxicity.

  Neurotoxicology and teratology 20110101

• A pharmacogenomic method for individualized prediction of drug sensitivity.

  Molecular systems biology 20110101

• Histone deacetylase inhibition enhances self renewal and cardioprotection by human cord blood-derived CD34 cells.

  PloS one 20110101

• Latent HIV in primary T lymphocytes is unresponsive to histone deacetylase inhibitors.

  Virology journal 20110101

• Progress on the issue of excitotoxic injury modification vs. real neuroprotection; implications for post-traumatic epilepsy.

  Neuropharmacology 20110101

• Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis.

  BMC cancer 20110101

• Efficacy of paroxetine in primary palmoplantar hyperhidrosis occurring with juvenile myoclonic epilepsy.

  Dermatology (Basel, Switzerland) 20110101

• Cytogenetic effects of valproic acid and ziprasidone in human lymphocyte cultures.

  Neuropsychobiology 20110101

• [Epilepsy in elderly].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• Fasted state bioavailability of two delayed release formulations of divalproex sodium in healthy Iranian volunteers.

  Arzneimittel-Forschung 20110101

• Effects of the histone deacetylase inhibitor valproic acid on human pericytes in vitro.

  PloS one 20110101

• [Pancytopenia in the course of acute valproic acid poisoning--case report].

  Przeglad lekarski 20110101

• mGluR5-antagonist mediated reversal of elevated stereotyped, repetitive behaviors in the VPA model of autism.

  PloS one 20110101

• HDAC activity is required during Xenopus tail regeneration.

  PloS one 20110101

• Antiepleptic drug interactions: a clinical case demonstration.

  Casopis lekaru ceskych 20110101

• [Therapeutic evidence for manic episode].

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20110101

• The effects of antiepileptic drugs on the relationships between leptin levels and bone turnover in prepubertal children with epilepsy.

  Journal of pediatric endocrinology & metabolism : JPEM 20110101

• Prescribing trends in bipolar disorder: cohort study in the United Kingdom THIN primary care database 1995-2009.

  PloS one 20110101

• Anticancer agent ellipticine combined with histone deacetylase inhibitors, valproic acid and trichostatin A, is an effective DNA damage strategy in human neuroblastoma.

  Neuro endocrinology letters 20110101

• Effects of valproic acid (VPA) and levetiracetam (LEV) on proliferation, apoptosis and hormone secretion of the human choriocarcinoma BeWo cell line.

  Pharmacological reports : PR 20110101

• Chromatin remodeling, cell proliferation and cell death in valproic acid-treated HeLa cells.

  PloS one 20110101

• [Molecular genetic mechanisms of individual sensitivity to synthetic fatty acids in case of valproic acid].

  Gigiena i sanitariia 20110101

• Kynurenic acid: a new effector of valproate action?

  Pharmacological reports : PR 20110101

• [Genetic performance criteria for valproate in patients with epilepsy].

  Likars'ka sprava 20110101

• Valproic acid modulates brain plasticity through epigenetic chromatin remodeling in the blind rat: implications for human sight recovery.

  Proceedings of the Western Pharmacology Society 20110101

• [Transitory cognitive dysfunction in rolandic epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• [Idiopathic focal epilepsies of infancy and childhood].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• [Epilepsies with electric status epilepticus in sleep: peculiarities of clinical course and rational approaches to treatment].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• [Valproic acid pharmacogenetics in an individual approach to treatment of women of childbearing age with epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20110101

• Validating γ oscillations and delayed auditory responses as translational biomarkers of autism.

  Biological psychiatry 20101215

• Olanzapine in the long-term treatment of bipolar disorder: a systematic review and meta-analysis.

  Journal of psychopharmacology (Oxford, England) 20101201

• Histone deacetylase inhibitors suppress the expression of inflammatory and innate immune response genes in human microglia and astrocytes.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20101201

• Posttraumatic stress disorder in children and adolescents: a review of psychopharmacological treatment.

  Child psychiatry and human development 20101201

• Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer.

  Annals of surgical oncology 20101201

• The study of the lipophilicity of some aminoalkanol derivatives with anticonvulsant activity.

  Biomedical chromatography : BMC 20101201

• Inhibition of class IIb histone deacetylase significantly improves cloning efficiency in mice.

  Biology of reproduction 20101201

• Histone deacetylase 2 is required for chromatin condensation and subsequent enucleation of cultured mouse fetal erythroblasts.

  Haematologica 20101201

• Effects of three N-(carboxyanilinomethyl) derivatives of p-isopropoxyphenylsuccinimide on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model.

  European journal of pharmacology 20101201

• Effects of valproate on neurotransmission associated with ryanodine receptors.

  Neuroscience research 20101201

• Role of oxidative metabolism in the effect of valproic acid on markers of cell viability, necrosis, and oxidative stress in sandwich-cultured rat hepatocytes.

  Toxicological sciences : an official journal of the Society of Toxicology 20101201

• Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives.

  European journal of medicinal chemistry 20101201

• Transplacental genotoxicity of antiepileptic drugs: animal model and pilot study on mother/newborn cohort.

  Reproductive toxicology (Elmsford, N.Y.) 20101201

• Sodium valproate, a histone deacetylase inhibitor, augments the expression of cell-surface NKG2D ligands, MICA/B, without increasing their soluble forms to enhance susceptibility of human osteosarcoma cells to NK cell-mediated cytotoxicity.

  Oncology reports 20101201

• Evaluation of a screening method by liquid chromatography-tandem mass spectrometry for estimating effect of drugs on the activation and β-oxidation of fatty acids in mitochondria.

  The Journal of pharmacy and pharmacology 20101201

• Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.

  Epileptic disorders : international epilepsy journal with videotape 20101201

• Unilateral opercular lesion and eating-induced seizures.

  Epileptic disorders : international epilepsy journal with videotape 20101201

• [Effect of valproic acid on apoptosis of leukemia HL-60 cells and expression of h-tert gene].

  Zhongguo shi yan xue ye xue za zhi 20101201

• [Effect of sodium valproate on human myelodysplastic syndrome cell line SKM-1 and its mechanism].

  Zhongguo shi yan xue ye xue za zhi 20101201

• [Good effect of valproate against aggression in Huntington disease. Only two cases reported earlier].

  Lakartidningen 20101201

• Retrograde ejaculation and abnormal hormonal profile in a subject under treatment with valproate and phenytoin.

  Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica 20101201

• [Valproate-induced hyperammononemic encefalopathy].

  Recenti progressi in medicina 20101201

• Effects of breastfeeding in children of women taking antiepileptic drugs.

  Neurology 20101130

• Valproate attenuates the development of morphine antinociceptive tolerance.

  Neuroscience letters 20101119

• [Epileptic spasms without hypsarrhythmia. A new case report and review of the literature].

  Revista de neurologia 20101116

• Mechanisms of synergistic antileukemic interactions between valproic acid and cytarabine in pediatric acute myeloid leukemia.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20101115

• Histone modifications regulate the norepinephrine transporter gene.

  Cell cycle (Georgetown, Tex.) 20101115

• Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors.

  Blood 20101111

• Trial against epilepsy drug manufacturer collapses after legal aid is withdrawn.

  BMJ (Clinical research ed.) 20101110

• [Valproate-meropenem interaction as an example of information shortcomings in relevant drug interactions].

  Medicina clinica 20101106

• Growth hormone levels in children and adolescents with epilepsy.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20101101

• [Tuberous sclerosis and intracranial aneurysms: a rare association].

  Revue neurologique 20101101

• [Characteristics of the children with epilepsy followed in the Marrakech University Hospital].

  Revue neurologique 20101101

• Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity.

  Reproductive toxicology (Elmsford, N.Y.) 20101101

• The mood stabilizer valproic acid improves defective neurite formation caused by Charcot-Marie-Tooth disease-associated mutant Rab7 through the JNK signaling pathway.

  Journal of neuroscience research 20101101

• Epigenetic modifications in valproic acid-induced teratogenesis.

  Toxicology and applied pharmacology 20101101

• The effect of valproate and levetiracetam on steroidogenesis in forskolin-stimulated H295R cells.

  Epilepsia 20101101

• Presence of epileptiform discharges on initial EEGs are associated with failure of retention on first antiepileptic drug in newly diagnosed cryptogenic partial epilepsy: a 2-year observational study.

  Seizure 20101101

• Neuropsychological and behavioural aspects in children and adolescents with idiopathic epilepsy at diagnosis and after 12 months of treatment.

  Seizure 20101101

• Demethylation of specific Wnt/β-catenin pathway genes and its upregulation in rat brain induced by prenatal valproate exposure.

  Anatomical record (Hoboken, N.J. : 2007) 20101101

• Epigenetic alteration of the NF-κB-inducing kinase (NIK) gene is involved in enhanced NIK expression in basal-like breast cancer.

  Cancer science 20101101

• Compound muscle action potential and motor function in children with spinal muscular atrophy.

  Muscle & nerve 20101101

• Is lamotrigine a significant human teratogen? Observations from the Australian Pregnancy Register.

  Seizure 20101101

• Drug treatment failures and effectivity in children with newly diagnosed epilepsy.

  Seizure 20101101

• Correlation between EEG abnormalities and symptoms of autism spectrum disorder (ASD).

  Brain & development 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Profile of children with migraine.

  Indian journal of pediatrics 20101101

• Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.

  Seizure 20101101

• Rufinamide in children and adults with Lennox-Gastaut syndrome: first Italian multicenter experience.

  Seizure 20101101

• Tibial developmental field defect in valproic acid embryopathy: Report on three cases.

  American journal of medical genetics. Part A 20101101

• Factors influencing valproate pharmacokinetics in children and adults.

  International journal of clinical pharmacology and therapeutics 20101101

• Polymerase γ gene POLG determines the risk of sodium valproate-induced liver toxicity.

  Hepatology (Baltimore, Md.) 20101101

• [Evaluation of haemostasis in children treated with valproic acid].

  Hamostaseologie 20101101

• Penetrating cranionasal injury in a child caused by a bicycle spoke.

  Pediatric emergency care 20101101

• Commentary: the Bipolar Affective Disorder: Lithium/Anticonvulsant Evaluation (BALANCE) study.

  Bipolar disorders 20101101

• A much needed BALANCE.

  Bipolar disorders 20101101

• The antitumour effect of {gamma}{delta} T-cells is enhanced by valproic acid-induced up-regulation of NKG2D ligands.

  Anticancer research 20101101

• Dose-dependent pharmacokinetics of toxic metabolites is not related to increased toxicity following high-dose valproic acid in rats.

  Journal of applied toxicology : JAT 20101101

• Effect of omega-3 fatty acids on valproate plasma protein binding.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20101101

• Kleine-Levin syndrome: the first typical case in Thailand.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20101101

• High content analysis of histone acetylation in human cells and tissues.

  Journal of neuroscience methods 20101030

• Valproic acid use in pregnancy and congenital malformations.

  The New England journal of medicine 20101028

• Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid.

  Neuroscience 20101013

• Curcumin p38-dependently enhances the anticancer activity of valproic acid in human leukemia cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101009

• Adjunctive valproate in panic disorder patients with comorbid bipolar disorder or otherwise resistant to standard antidepressants: a 3-year 'open' follow-up study.

  European archives of psychiatry and clinical neuroscience 20101001

• Effects of mood stabilizers on mitochondrial respiratory chain activity in brain of rats treated with d-amphetamine.

  Journal of psychiatric research 20101001

• Antiepileptic drugs modify power of high EEG frequencies and their neural generators.

  European journal of neurology 20101001

• Effect of CPS14217C>A genotype on valproic-acid-induced hyperammonemia.

  Pediatrics international : official journal of the Japan Pediatric Society 20101001

• Long-term outcome of 32 children with encephalopathy with status epilepticus during sleep, or ESES syndrome.

  Epilepsia 20101001

• Incidence, severity, and etiology of drug-induced acute pancreatitis.

  Digestive diseases and sciences 20101001

• Effects of valproate and carbamazepine monotherapy on neuroactive steroids, their precursors and metabolites in adult men with epilepsy.

  The Journal of steroid biochemistry and molecular biology 20101001

• Characterization of inhibitory effect of carbapenem antibiotics on the deconjugation of valproic acid glucuronide.

  Drug metabolism and disposition: the biological fate of chemicals 20101001

• Histone deacetylase inhibitors synergistically potentiate death receptor 4-mediated apoptotic cell death of human T-cell acute lymphoblastic leukemia cells.

  Apoptosis : an international journal on programmed cell death 20101001

• Valproic acid as a therapy for adenomyosis: a comparative case series.

  Reproductive sciences (Thousand Oaks, Calif.) 20101001

• Influence of CYP2C9 polymorphism on metabolism of valproate and its hepatotoxin metabolite in Iranian patients.

  Toxicology mechanisms and methods 20101001

• The mood stabilizers valproic acid and lithium enhance mesenchymal stem cell migration via distinct mechanisms.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20101001

• A double-blind, placebo-controlled study with quetiapine as adjunct therapy with lithium or divalproex in bipolar I patients with coexisting alcohol dependence.

  Alcoholism, clinical and experimental research 20101001

• Early cognitive development in children born to women with epilepsy: a prospective report.

  Epilepsia 20101001

• Protection of dopaminergic cells from MPP+-mediated toxicity by histone deacetylase inhibition.

  Brain research 20101001

• Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study.

  The Journal of clinical psychiatry 20101001

• HDAC inhibitors augment cytotoxic activity of rituximab by upregulating CD20 expression on lymphoma cells.

  Leukemia 20101001

• Phase I pharmacokinetic and pharmacodynamic evaluation of combined valproic acid/doxorubicin treatment in dogs with spontaneous cancer.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20101001

• Effects of AEDs on biomarkers in people with epilepsy: CRP, HbA1c and eGFR.

  Epilepsy research 20101001

• Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20101001

• [Management of severe valproic acid poisoning: first optimize supportive treatments].

  Annales francaises d'anesthesie et de reanimation 20101001

• Valproic acid and ADHD symptoms in fragile X syndrome: more evidence is needed.

  American journal of medical genetics. Part A 20101001

• Comparative pharmacodynamic and pharmacokinetic analysis of two anticonvulsant halo derivatives of 2,2,3,3-tetramethylcyclopropanecarboxamide, an amide of a cyclic analog of valproic acid.

  Epilepsia 20101001

• Histone deacetylase inhibitors valproic acid and depsipeptide sensitize retinoblastoma cells to radiotherapy by increasing H2AX phosphorylation and p53 acetylation-phosphorylation.

  International journal of oncology 20101001

• C825T polymorphism of the GNB3 gene on valproate-related metabolic abnormalities in bipolar disorder patients.

  Journal of clinical psychopharmacology 20101001

• Age and comedications influence levetiracetam pharmacokinetics in children.

  Pediatric neurology 20101001

• Fatal hydrocodone overdose in a child: pharmacogenetics and drug interactions.

  Pediatrics 20101001

• Combination of the histone deacetylase inhibitor valproic acid with oral hydroxyurea or 6-mercaptopurin can be safe and effective in patients with advanced acute myeloid leukaemia--a report of five cases.

  Hematology (Amsterdam, Netherlands) 20101001

• Sodium valproate for prevention of early posttraumatic seizures.

  Chinese journal of traumatology = Zhonghua chuang shang za zhi 20101001

• Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines.

  European journal of cancer (Oxford, England : 1990) 20101001

• Effects of sodium valproate on behavioral disturbances in elderly outpatients with dementia.

  Geriatrics & gerontology international 20101001

• Adult nonhepatic hyperammonemia: a case report and differential diagnosis.

  The American journal of medicine 20101001

• Respiratory alkalosis and metabolic acidosis in a child treated with sulthiame.

  Pediatric emergency care 20101001

• Bipolar disorder and valproate-induced hyperammonemic encephalopathy in an adolescent with diabetes.

  Journal of child and adolescent psychopharmacology 20101001

• Valproic acid attenuates the multiple-organ dysfunction in a rat model of septic shock.

  Chinese medical journal 20101001

• Valproic acid and phenobarbital blood levels during the first month of treatment with the ketogenic diet.

  Acta neurologica Scandinavica 20101001

• Improvement of pentylenetetrazol-induced learning deficits by valproic acid in the adult zebrafish.

  European journal of pharmacology 20100925

• The role of p38 MAPK in valproic acid induced microglia apoptosis.

  Neuroscience letters 20100920

• Induction of a CD8+ T-cell response to the MAGE cancer testis antigen by combined treatment with azacitidine and sodium valproate in patients with acute myeloid leukemia and myelodysplasia.

  Blood 20100916

• Anticonvulsant potential of the peroxisome proliferator-activated receptor γ agonist pioglitazone in pentylenetetrazole-induced acute seizures and kindling in mice.

  Brain research 20100910

• [Non-convulsive status epilepticus in 12-year-old].

  Ugeskrift for laeger 20100906

• Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.

  Biochimie 20100901

• Role of parental risk factors in the aetiology of isolated non-syndromic metopic craniosynostosis.

  The British journal of oral & maxillofacial surgery 20100901

• Identification of valproic acid glucuronide hydrolase as a key enzyme for the interaction of valproic acid with carbapenem antibiotics.

  Drug metabolism and disposition: the biological fate of chemicals 20100901

• N'-[(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)methylene] 2/4-substituted hydrazides: synthesis and anticonvulsant activity.

  European journal of medicinal chemistry 20100901

• Design & synthesis of 2-(substituted aryloxy)-5-(substituted benzylidene)-3-phenyl-2,5-dihydro-1H-[1,2,4] triazin-6-one as potential anticonvulsant agents.

  European journal of medicinal chemistry 20100901

• Epigenetic modification of vomeronasal (V2r) precursor neurons by histone deacetylation.

  Neuroscience 20100901

• Pharmacologic resuscitation promotes survival and attenuates hemorrhage-induced activation of extracellular signal-regulated kinase 1/2.

  The Journal of surgical research 20100901

• Effect of valproic acid treatment on copper availability in adult epileptic patients.

  Clinical biochemistry 20100901

• Effect of antiepileptic drugs and reactive oxygen species on folate receptor 1 (FOLR1)-dependent 5-methyltetrahydrofolate transport.

  Molecular genetics and metabolism 20100901

• Isolation of a fission yeast mutant that is sensitive to valproic acid and defective in the gene encoding Ric1, a putative component of Ypt/Rab-specific GEF for Ryh1 GTPase.

  Molecular genetics and genomics : MGG 20100901

• Milder phenotype with SCN1A truncation mutation other than SMEI.

  Seizure 20100901

• Absence epilepsy and periventricular nodular heterotopia.

  Seizure 20100901

• Enhancement of radiation response in osteosarcoma and rhabdomyosarcoma cell lines by histone deacetylase inhibition.

  International journal of radiation oncology, biology, physics 20100901

• Quality of life and treatment satisfaction in Spanish epilepsy patients on monotherapy with lamotrigine or valproic acid.

  Seizure 20100901

• HDAC inhibition attenuates inflammatory, hypertrophic, and hypertensive responses in spontaneously hypertensive rats.

  Hypertension (Dallas, Tex. : 1979) 20100901

• [Childhood epilepsy with centrotemporal spikes in Marrakech].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20100901

• Benign infantile focal epilepsy with midline spikes and waves during sleep: a new epileptic syndrome or a variant of benign focal epilepsy?

  Epileptic disorders : international epilepsy journal with videotape 20100901

• Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder.

  Bipolar disorders 20100901

• Complexity of pharmacologic treatment required for sustained improvement in outpatients with bipolar disorder.

  The Journal of clinical psychiatry 20100901

• Angiotensin AT1 receptor antagonists enhance the anticonvulsant action of valproate in the mouse model of maximal electroshock.

  European journal of pharmacology 20100825

• Disturbance in long distance gamma coherence in bipolar disorder.

  Progress in neuro-psychopharmacology & biological psychiatry 20100816

• Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes.

  Epigenetics 20100816

• Valproic acid enhances microglial phagocytosis of amyloid-beta(1-42).

  Neuroscience 20100811

• Valproate and bone loss: iTRAQ proteomics show that valproate reduces collagens and osteonectin in SMA cells.

  Journal of proteome research 20100806

• Multiple organ dysfunction syndrome: infection or hypersensitivity reaction?

  European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20100801

• Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP.

  Epilepsia 20100801

• Divalproex sodium versus placebo in the treatment of acute bipolar depression: a systematic review and meta-analysis.

  Journal of affective disorders 20100801

• The role of valproate in metabolic disturbances in bipolar disorder patients.

  Journal of affective disorders 20100801

• Weight gain and insulin resistance in children treated with valproate: the influence of time.

  Journal of child neurology 20100801

• A potential activity of valproic acid in the stimulation of interleukin-3-mediated megakaryopoiesis and erythropoiesis.

  Experimental hematology 20100801

• CD45+/CD133+ positive cells expanded from umbilical cord blood expressing PDX-1 and markers of pluripotency.

  Cell biology international 20100801

• ECoG studies of valproate, carbamazepine and halothane in frontal-lobe epilepsy induced by head injury in the rat.

  Experimental neurology 20100801

• Modulation of synaptic transmission and analysis of neuroprotective effects of valproic Acid and derivates in rat embryonic motoneurons.

  Cellular and molecular neurobiology 20100801

• Use of valproate in women of childbearing potential: pre- and post-NICE bipolar guidelines.

  Archives of women's mental health 20100801

• Genetic and maternal effects on valproic acid teratogenesis in C57BL/6J and DBA/2J mice.

  Toxicological sciences : an official journal of the Society of Toxicology 20100801

• Sorafenib plus valproic acid for infant spinal glioblastoma.

  Journal of pediatric hematology/oncology 20100801

• Interactions of stiripentol with clobazam and valproate in the mouse maximal electroshock-induced seizure model.

  Epilepsy research 20100801

• Valproic acid inhibits proliferation of human coronary vascular cells (SI/MPL-ratio: 0.5): a novel candidate for systemic and local therapy of postinterventional restenosis.

  Coronary artery disease 20100801

• [Multiple cerebral cavernomatosis in a 1-year-old child].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20100801

• A randomized trial of propranolol versus sodium valproate for the prophylaxis of migraine in pediatric patients.

  Paediatric drugs 20100801

• Decrease in serum valproic acid levels during treatment with ertapenem.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100801

• A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression.

  Archives of general psychiatry 20100801

• Does folic acid use decrease the risk for spina bifida after in utero exposure to valproic acid?

  Pharmacoepidemiology and drug safety 20100801

• Comparison between the effects of valproic acid and trichostatin A on the in vitro development, blastocyst quality, and full-term development of mouse somatic cell nuclear transfer embryos.

  Cellular reprogramming 20100801

• Familial hyperinsulinism-hyperammonemia syndrome in a family with seizures: case report.

  Journal of pediatric endocrinology & metabolism : JPEM 20100801

• Effect of combined treatment of thioperamide with some antiepileptic drugs on methionine-sulfoximine induced convulsions in mice.

  Indian journal of experimental biology 20100801

• Valproate-induced reversible hemichorea.

  Movement disorders : official journal of the Movement Disorder Society 20100730

• Valproic acid enhances recombinant mRNA and protein levels in transiently transfected Chinese hamster ovary cells.

  Journal of biotechnology 20100720

• Novel semicarbazones based 2,5-disubstituted-1,3,4-oxadiazoles: one more step towards establishing four binding site pharmacophoric model hypothesis for anticonvulsant activity.

  Bioorganic & medicinal chemistry letters 20100715

• HDAC inhibitors conquer Polycomb proteins.

  Cell cycle (Georgetown, Tex.) 20100715

• Animal model of autism using GSTM1 knockout mice and early post-natal sodium valproate treatment.

  Behavioural brain research 20100711

• p21 Downregulation is an important component of PAX3/FKHR oncogenicity and its reactivation by HDAC inhibitors enhances combination treatment.

  Oncogene 20100708

• Valproate treatment of human cord blood CD4-positive effector T cells confers on them the molecular profile (microRNA signature and FOXP3 expression) of natural regulatory CD4-positive cells through inhibition of histone deacetylase.

  The Journal of biological chemistry 20100702

• Differential modulation of intracellular Ca2+ responses in B lymphoblasts by mood stabilizers.

  The international journal of neuropsychopharmacology 20100701

• Weight gain, obesity, and metabolic indices following a first manic episode: prospective 12-month data from the Systematic Treatment Optimization Program for Early Mania (STOP-EM).

  Journal of affective disorders 20100701

• Divalproex extended-release in acute bipolar II depression.

  Journal of affective disorders 20100701

• A combined pretreatment of 1,25-dihydroxyvitamin D3 and sodium valproate enhances the damaging effect of ionizing radiation on prostate cancer cells.

  The Journal of steroid biochemistry and molecular biology 20100701

• Lithium-induced gray matter volume increase as a neural correlate of treatment response in bipolar disorder: a longitudinal brain imaging study.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100701

• Valproic acid-associated vanishing bile duct syndrome.

  Journal of child neurology 20100701

• Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?

  Seizure 20100701

• Can we prevent fatal liver failure under valproate?

  Pharmacopsychiatry 20100701

• Valproic acid enhances Oct4 promoter activity in myogenic cells.

  Journal of cellular biochemistry 20100701

• Stability of sodium valproate tablets repackaged into dose administration aids.

  The Journal of pharmacy and pharmacology 20100701

• [Prophylactic efficacy of levetiracetam, valproate or phenobarbital on febrile convulsions in rats].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100701

• Pharmacokinetic drug-drug interactions between olanzapine and valproate need to be better studied.

  The Journal of clinical psychiatry 20100701

• [A case of Lissauer form of paretic neurosyphilis with drop attacks and dementia].

  Rinsho shinkeigaku = Clinical neurology 20100701

• Sydenham's chorea: a practical overview of the current literature.

  Pediatric neurology 20100701

• Quantitation of valproic acid in pharmaceutical preparations using dispersive liquid-liquid microextraction followed by gas chromatography-flame ionization detection without prior derivatization.

  Drug testing and analysis 20100701

• Modular glass chip system measuring the electric activity and adhesion of neuronal cells--application and drug testing with sodium valproic acid.

  Lab on a chip 20100621

• New aryldithiolethione derivatives as potent histone deacetylase inhibitors.

  Bioorganic & medicinal chemistry 20100615

• Valproic acid monotherapy in pregnancy and major congenital malformations.

  The New England journal of medicine 20100610

• Potent neuroprotective effects of novel structural derivatives of valproic acid: potential roles of HDAC inhibition and HSP70 induction.

  Neuroscience letters 20100607

• Magnesium supplementation enhances the anticonvulsant potential of valproate in pentylenetetrazol-treated rats.

  Brain research 20100602

• L-methionine decreases dendritic spine density in mouse frontal cortex.

  Neuroreport 20100602

• Clinical alertness to valproic acid-induced hyperammonemia--two case reports.

  Journal of psychopharmacology (Oxford, England) 20100601

• Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain.

  Journal of psychiatric research 20100601

• Divalproex sodium-ER in outpatients with disruptive behavior disorders: a three month open label study.

  Child psychiatry and human development 20100601

• Efficacy of sodium valproate and haloperidol in the management of acute mania: a randomized open-label comparative study.

  Journal of clinical pharmacology 20100601

• All is not lost: utilizing continuous remote ILR monitoring to diagnose syncope.

  Pacing and clinical electrophysiology : PACE 20100601

• Valproate-induced hyperammonemic encephalopathy, rapidly improved by i.v. carnitine and glucose/thiamine.

  Scandinavian journal of gastroenterology 20100601

• Adverse effects of valproate on bone: defining a model to investigate the pathophysiology.

  Epilepsia 20100601

• TrkB/BDNF-dependent striatal plasticity and behavior in a genetic model of epilepsy: modulation by valproic acid.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601

• Decrease of intracellular pH as possible mechanism of embryotoxicity of glycol ether alkoxyacetic acid metabolites.

  Toxicology and applied pharmacology 20100601

• Twelve-month prospective, multinational, observational study of factors associated with recovery from mania in bipolar disorder in patients treated with atypical antipsychotics.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20100601

• The differential diagnoses of parkinsonism: findings from a cohort of 1528 patients and a 10 years comparison in tertiary movement disorders clinics.

  Clinical neurology and neurosurgery 20100601

• Participation of lipid transport and fatty acid metabolism in valproate sodium-induced hepatotoxicity in HepG2 cells.

  Toxicology in vitro : an international journal published in association with BIBRA 20100601

• Levetiracetam in submaximal subcutaneous pentylentetrazol-induced seizures in rats.

  Seizure 20100601

• Assessment of safety, tolerability and effectiveness of adjunctive aripiprazole to lithium/valproate in bipolar mania: a 46-week, open-label extension following a 6-week double-blind study.

  Current medical research and opinion 20100601

• Preclinical evidence for a beneficial impact of valproate on the response of small cell lung cancer to first-line chemotherapy.

  European journal of cancer (Oxford, England : 1990) 20100601

• Sodium valproate in the treatment of Sydenham's chorea.

  Indian journal of pediatrics 20100601

• Pharmacological prophylaxis of chronic migraine: a review of double-blind placebo-controlled trials.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20100601

• Hematological effects of valproate in psychiatric patients: what are the risk factors?

  Journal of clinical psychopharmacology 20100601

• Valproate and risk of fracture in Rett syndrome.

  Archives of disease in childhood 20100601

• [Valproate for treatment of women with epilepsy: recommendations of the German Society for Epileptology].

  Der Nervenarzt 20100601

• Etiological heterogeneity and clinical characteristics of metopic synostosis: Evidence from a tertiary craniofacial unit.

  American journal of medical genetics. Part A 20100601

• Treatment with valproic acid ameliorates ADHD symptoms in fragile X syndrome boys.

  American journal of medical genetics. Part A 20100601

• An older drug for childhood absence epilepsy.

  The American journal of nursing 20100601

• Valproic acid administration for hepatic fibrosis: a balance between antifibrotic efficacy and hepatotoxicity.

  Hepatology (Baltimore, Md.) 20100601

• Toxic epidermal necrolysis with severe hyperbilirubinemia: complete re-epithelialization after bilirubin reduction therapies.

  The Journal of dermatology 20100601

• [Effect of UGTIA6 A541G genetic polymorphism on the metabolism of valproic acid in Han epileptic children from Henan].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100601

• [Effects of valproate acid on blood lipid, serum leptin and cerebral cortex in juvenile and adult rats].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100601

• [Changes of body mass index and plasma galanin in children with epilepsy following valproate sodium treatment].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100601

• Epigenetic treatments of adult rats promote recovery from visual acuity deficits induced by long-term monocular deprivation.

  The European journal of neuroscience 20100601

• [Inhibitory effect of VPA on multiple myeloma U266 cell proliferation and regulation of histone acetylation].

  Zhongguo shi yan xue ye xue za zhi 20100601

• [Sense and sensibility: bipolar affective disorder as a battlefield of cognitions and emotions--lamotrigine therapy as a peacekeeper].

  Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20100601

• Probable valproate sodium-associated hypotension.

  The American journal of geriatric pharmacotherapy 20100601

• Valnoctamide as a valproate substitute with low teratogenic potential in mania: a double-blind, controlled, add-on clinical trial.

  Bipolar disorders 20100601

• Medical comorbidity in bipolar disorder: relationship between illnesses of the endocrine/metabolic system and treatment outcome.

  Bipolar disorders 20100601

• Efficacy of olanzapine and sodium valproate given alone or as add-on therapy in acute mania. A comparative study.

  Methods and findings in experimental and clinical pharmacology 20100601

• Intravenous valproate for seizures in 137 Taiwanese children - valproate naive and non-naive.

  Acta neurologica Taiwanica 20100601

• [Effect of Chaihu Shugan Tang on excitability in different brain regions of pentylenetetrazole-kindled chronic epileptic rats].

  Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100601

• The role of intravenous valproate in convulsive status epilepticus in the future.

  Acta neurologica Taiwanica 20100601

• Neonatal episodic hypoglycemia: a finding of valproic acid withdrawal.

  Journal of clinical research in pediatric endocrinology 20100601

• Quetiapine as add-on treatment for bipolar I disorder with comorbid compulsive buying and physical exercise addiction.

  Progress in neuro-psychopharmacology & biological psychiatry 20100530

• Suberoylanilide hydroxamic acid induces viral lytic cycle in Epstein-Barr virus-positive epithelial malignancies and mediates enhanced cell death.

  International journal of cancer 20100515

• Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.

  Human molecular genetics 20100515

• Pharmacological response in juvenile bipolar disorder subtypes: A naturalistic retrospective examination.

  Psychiatry research 20100515

• Executive functioning in adult patients with Sydenham's chorea.

  Movement disorders : official journal of the Movement Disorder Society 20100515

• Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease.

  Neuroscience letters 20100514

• Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.

  Journal of medicinal chemistry 20100513

• Dithiolethione modified valproate and diclofenac increase E-cadherin expression and decrease proliferation of non-small cell lung cancer cells.

  Lung cancer (Amsterdam, Netherlands) 20100501

• The teratogenic risk of antiepileptic drug polytherapy.

  Epilepsia 20100501

• Adverse effects of carbamazepine, phenytoin, valproate and lamotrigine monotherapy in epileptic adult Chinese patients.

  Clinical neurology and neurosurgery 20100501

• The influence of cytochrome oxidase CYP2A6, CYP2B6, and CYP2C9 polymorphisms on the plasma concentrations of valproic acid in epileptic patients.

  Clinical neurology and neurosurgery 20100501

• Antiepileptogenic and anticonvulsive actions of levetiracetam in a pentylenetetrazole kindling model.

  Epilepsy research 20100501

• The effect of water on particle size, porosity and the rate of drug release from implanted titania reservoirs.

  Journal of biomedical materials research. Part B, Applied biomaterials 20100501

• Phase I trial of ATRA-IV and Depakote in patients with advanced solid tumor malignancies.

  Cancer biology & therapy 20100501

• Loss of response after switching from brand name to generic formulations: three cases and a discussion of key clinical considerations when switching.

  International clinical psychopharmacology 20100501

• The histone deacetylase inhibitor ITF2357 decreases surface CXCR4 and CCR5 expression on CD4(+) T-cells and monocytes and is superior to valproic acid for latent HIV-1 expression in vitro.

  Journal of acquired immune deficiency syndromes (1999) 20100501

• Randomized, double-blind, placebo-controlled study of divalproex extended release loading monotherapy in ambulatory bipolar spectrum disorder patients with moderate-to-severe hypomania or mild mania.

  The Journal of clinical psychiatry 20100501

• When the past challenges the present: are older antiepileptic drugs still the best choice in childhood absence epilepsy?

  The Lancet. Neurology 20100501

• [Valproic acid as a histone deacetylase inhibitor. New application for a well-known drug].

  Pharmazie in unserer Zeit 20100501

• Effects of valproate, carbamazepine, and levetiracetam on the antioxidant and oxidant systems in epileptic patients and their clinical importance.

  Clinical neuropharmacology 20100501

• Preventing relapse in bipolar disorder.

  The Harvard mental health letter 20100501

• An experimental study of the anticonvulsant effect of amlodipine in mice.

  Singapore medical journal 20100501

• Molecular adsorbent recycling system therapy in the treatment of acute valproic acid intoxication.

  The Israel Medical Association journal : IMAJ 20100501

• Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome.

  Oncotarget 20100501

• The BALANCE trial.

  Lancet (London, England) 20100417

• The BALANCE trial.

  Lancet (London, England) 20100417

• Valproate-induced hyperammonemia in mental retardation: a case report and review of the literature.

  Progress in neuro-psychopharmacology & biological psychiatry 20100416

• Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide.

  Oncogene 20100415

• MMP28 gene expression is regulated by Sp1 transcription factor acetylation.

  The Biochemical journal 20100414

• Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein.

  The Journal of biological chemistry 20100402

• Inhibition of growth in medullary thyroid cancer cells with histone deacetylase inhibitors and lithium chloride.

  The Journal of surgical research 20100401

• Inhibition of bladder tumour growth by histone deacetylase inhibitor.

  BJU international 20100401

• Valproate for the treatment of acute bipolar depression: systematic review and meta-analysis.

  Journal of affective disorders 20100401

• Histone deacetylase controls adult stem cell aging by balancing the expression of polycomb genes and jumonji domain containing 3.

  Cellular and molecular life sciences : CMLS 20100401

• Triazole incorporated thiazoles as a new class of anticonvulsants: design, synthesis and in vivo screening.

  European journal of medicinal chemistry 20100401

• The effect of epigenetic therapy on congenital neurogenic bladders--a pilot study.

  Urology 20100401

• POLG DNA testing as an emerging standard of care before instituting valproic acid therapy for pediatric seizure disorders.

  Seizure 20100401

• Treatment and long term outcome in West syndrome: the clinical reality. A multicentre follow up study.

  Seizure 20100401

• Quantitative analysis of motor performance in epilepsy patients treated with valproate.

  Seizure 20100401

• Long-term efficacy of valproate versus lamotrigine in treatment of idiopathic generalized epilepsies in children and adolescents.

  Seizure 20100401

• Interleaved transcranial magnetic stimulation and fMRI suggests that lamotrigine and valproic acid have different effects on corticolimbic activity.

  Psychopharmacology 20100401

• Sodium valproate, a histone deacetylase inhibitor, but not captopril, prevents right ventricular hypertrophy in rats.

  Circulation journal : official journal of the Japanese Circulation Society 20100401

• Radiopaque stomach contents in postmortem CT in suicidal oral medication intoxication: report of three cases.

  Journal of forensic and legal medicine 20100401

• Acute confusional migraine in an adolescent: response to intravenous valproate.

  Pediatrics 20100401

• Valproate semisodium ER for migraine and cluster headache prophylaxis.

  Expert opinion on drug metabolism & toxicology 20100401

• Fanconi syndrome caused by valproic acid.

  Pediatric neurology 20100401

• Bipolar affective disorder presenting as failure of parenting.

  The Australian and New Zealand journal of psychiatry 20100401

• Autophagy induced by valproic acid is associated with oxidative stress in glioma cell lines.

  Neuro-oncology 20100401

• Dialysis in the poisoned patient.

  Hemodialysis international. International Symposium on Home Hemodialysis 20100401

• A randomized, placebo-controlled, multicenter study of divalproex sodium extended-release in the acute treatment of mania.

  The Journal of clinical psychiatry 20100401

• A validated stability-indicating gas chromatography method for determination of divalproex sodium impurities in pharmaceutical preparation.

  Drug testing and analysis 20100401

• Polyspike and waves do not predict generalized tonic-clonic seizures in childhood absence epilepsy.

  Journal of child neurology 20100401

• [Toxic epidermal necrolysis associated to the use of valproic acid].

  Revista de neurologia 20100401

• Reversible rapidly progressive dementia with parkinsonism induced by valproate in a patient with systemic lupus erythematosus.

  Journal of the American Geriatrics Society 20100401

• Increase in valproic acid levels during riluzole treatment in an adolescent with autism.

  Journal of child and adolescent psychopharmacology 20100401

• Characterization of valproic acid-initiated homologous recombination.

  Birth defects research. Part B, Developmental and reproductive toxicology 20100401

• Modification in body weight associated with antiepileptic drugs.

  Arquivos de neuro-psiquiatria 20100401

• Psychiatric concerns in pediatric epilepsy.

  Child and adolescent psychiatric clinics of North America 20100401

• Probing past a seizure.

  Medicine and health, Rhode Island 20100401

• [Effects of sodium valproate on proliferation and apoptosis of Hep-2 cells and associated mechanism].

  Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20100401

• Strain-specific BDNF expression of rat primary astrocytes.

  Journal of neuroimmunology 20100330

• Intraneuronal beta-amyloid accumulation in the amygdala enhances fear and anxiety in Alzheimer's disease transgenic mice.

  Biological psychiatry 20100315

• Effect of long-term valproate monotherapy on bone mineral density in adults with epilepsy.

  Journal of the neurological sciences 20100315

• Hippocampal synaptic plasticity, memory, and epilepsy: effects of long-term valproic acid treatment.

  Biological psychiatry 20100315

• Valproic acid reduces spatial working memory and cell proliferation in the hippocampus.

  Neuroscience 20100310

• Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.

  The New England journal of medicine 20100304

• Ethosuximide in childhood absence epilepsy--older and better.

  The New England journal of medicine 20100304

• Levetiracetam inhibits interleukin-1 beta inflammatory responses in the hippocampus and piriform cortex of epileptic rats.

  Neuroscience letters 20100303

• Improved seizure control by alternating therapy of levetiracetam and valproate in epileptic rats.

  Epilepsia 20100301

• Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.

  Epilepsia 20100301

• Antiepileptic drugs abolish ictal but not interictal epileptiform discharges in vitro.

  Epilepsia 20100301

• Chronic antiepileptic monotherapy, bone metabolism, and body composition in non-institutionalized children.

  Developmental medicine and child neurology 20100301

• The response to sodium valproate of patients with sinus headaches with normal endoscopic and CT findings.

  European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20100301

• Identification of a novel potential biomarker in a model of hemorrhagic shock and valproic acid treatment.

  The Journal of surgical research 20100301

• Vigabatrin but not valproate prevents development of age-specific flexion seizures induced by N-methyl-D-aspartate (NMDA) in immature rats.

  Epilepsia 20100301

• Magnetoencephalographic findings in two cases of juvenile myoclonus epilepsy.

  Brain topography 20100301

• The usefulness of olfactory bulb kindling as a model for evaluation of antiepileptics.

  Epilepsia 20100301

• Inhibition of hepatic carnitine palmitoyl-transferase I (CPT IA) by valproyl-CoA as a possible mechanism of valproate-induced steatosis.

  Biochemical pharmacology 20100301

• Divalproex sodium vs placebo for the treatment of irritability in children and adolescents with autism spectrum disorders.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100301

• Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis.

  Cancer science 20100301

• Treatment strategies targeting excess hippocampal activity benefit aged rats with cognitive impairment.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100301

• Management of refractory status epilepticus at a tertiary care centre in a developing country.

  Seizure 20100301

• Valproate in children with newly diagnosed idiopathic generalized epilepsy.

  Acta neurologica Scandinavica 20100301

• Modulation of coxsackie and adenovirus receptor expression for gene transfer to normal and dystrophic skeletal muscle.

  The journal of gene medicine 20100301

• Efficacy of valproate versus lithium in mania or mixed mania: a randomized, open 12-week trial.

  International clinical psychopharmacology 20100301

• The World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Biological Treatment of Bipolar Disorders: Update 2010 on the treatment of acute bipolar depression.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20100301

• Differential radiosensitizing effect of valproic acid in differentiation versus self-renewal promoting culture conditions.

  International journal of radiation oncology, biology, physics 20100301

• Partial seizures with affective semiology versus pavor nocturnus.

  Epileptic disorders : international epilepsy journal with videotape 20100301

• Valproic acid in the complex therapy of malignant tumors.

  Current drug targets 20100301

• Galactorrhea - side effect of risperidone in combination with depakine chrono in a patient with bipolar disorder.

  Psychiatria Danubina 20100301

• Infection or idiosyncratic reaction to antiepileptic drugs?

  Psychiatria Danubina 20100301

• Hyperammoneic encephalopathy, valproic acid, and benzodiazepine withdrawal: a case series.

  The American journal of drug and alcohol abuse 20100301

• Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamides.

  Journal of medicinal chemistry 20100211

• Behavior and serotonergic disorders in rats exposed prenatally to valproate: a model for autism.

  Neuroscience letters 20100205

• Sodium valproate in combination with ganciclovir induces lysis of EBV-infected lymphoma cells without impairing EBV-specific T-cell immunity.

  International journal of laboratory hematology 20100201

• [Iatrogenic dementia and extrapyramidal syndrome: rare adverse effect of valproic acid-aspirin combination].

  Presse medicale (Paris, France : 1983) 20100201

• Maintenance treatment received by patients with bipolar I and II disorders--a naturalistic prospective study.

  Journal of affective disorders 20100201

• Clinical and neurocognitive predictors of functional outcome in bipolar euthymic patients: a long-term, follow-up study.

  Journal of affective disorders 20100201

• Valproic acid exerts differential effects on CXCR4 expression in leukemic cells.

  Leukemia research 20100201

• HDAC inhibitor valproic acid enhances tumor cell kill in adenovirus-HSVtk mediated suicide gene therapy in HNSCC xenograft mouse model.

  International journal of cancer 20100201

• Effects of combined valproic acid and the epidermal growth factor/vascular endothelial growth factor receptor tyrosine kinase inhibitor AEE788 on renal cell carcinoma cell lines in vitro.

  BJU international 20100201

• Theoretical characterization of SOME amides and esters DERIVATIVES of valproic acid.

  Journal of molecular modeling 20100201

• Valproic acid is neuroprotective in the rotenone rat model of Parkinson's disease: involvement of alpha-synuclein.

  Neurotoxicity research 20100201

• The metabolic syndrome in overweight epileptic patients treated with valproic acid.

  Epilepsia 20100201

• A 12-month longitudinal study of calcium metabolism and bone turnover during valproate monotherapy.

  European journal of neurology 20100201

• Ghrelin levels are reduced in prepubertal epileptic children under treatment with carbamazepine or valproic acid.

  Epilepsia 20100201

• GABA and valproate modulate trigeminovascular nociceptive transmission in the thalamus.

  Neurobiology of disease 20100201

• Does valproic acid warrant therapeutic drug monitoring in bipolar affective disorder?

  Therapeutic drug monitoring 20100201

• Effects of histone deacetylase inhibitors on rat mesangial cells.

  American journal of physiology. Renal physiology 20100201

• Valproate and amitriptyline exert common and divergent influences on global and gene promoter-specific chromatin modifications in rat primary astrocytes.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100201

• Effect of mood stabilizers on gene expression in lymphoblastoid cells.

  Journal of neural transmission (Vienna, Austria : 1996) 20100201

• Chronic administration of valproic acid inhibits activation of mouse hepatic stellate cells in vitro and in vivo.

  Hepatology (Baltimore, Md.) 20100201

• Changing patterns of antiepileptic drug use in pregnant Australian women.

  Acta neurologica Scandinavica 20100201

• Effects of levetiracetam and valproic acid monotherapy on sex-steroid hormones in prepubertal children--results from a pilot study.

  Epilepsy research 20100201

• Monotherapy of epilepsy in women: psychiatric and neuroendocrine aspects.

  Neuroscience and behavioral physiology 20100201

• Experience in the use of the anticonvulsant pregabalin as an add-on therapy in patients with partial epilepsy with polymorphic seizures.

  Neuroscience and behavioral physiology 20100201

• Growth-inhibiting effects of arsenic trioxide plus epigenetic therapeutic agents on leukemia cell lines.

  Leukemia & lymphoma 20100201

• Ziprasidone plus a mood stabilizer in subjects with bipolar I disorder: a 6-month, randomized, placebo-controlled, double-blind trial.

  The Journal of clinical psychiatry 20100201

• Valproic acid enhances in vitro development and Oct-3/4 expression of miniature pig somatic cell nuclear transfer embryos.

  Cellular reprogramming 20100201

• When is a 'generic' medication not really a generic?

  Journal of psychosocial nursing and mental health services 20100201

• Epigenetic modifiers as anticancer drugs: effectiveness of valproic acid in neural crest-derived tumor cells.

  Anticancer research 20100201

• Valproic acid-induced pancreatitis in an adult.

  Arquivos de neuro-psiquiatria 20100201

• Inhibitory effect of valproic acid on ovarian androgen biosynthesis in rat theca-interstitial cells.

  Endocrine 20100201

• Study of valproic acid-induced endogenous and exogenous metabolite alterations using LC-MS-based metabolomics.

  Bioanalysis 20100201

• Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial.

  Lancet (London, England) 20100130

• A new BALANCE in bipolar I disorder.

  Lancet (London, England) 20100130

• Valproic acid as a promising agent to combat Alzheimer's disease.

  Brain research bulletin 20100115

• Valproic acid restores ER alpha and antiestrogen sensitivity to ER alpha-negative breast cancer cells.

  Molecular and cellular endocrinology 20100115

• Serum biotinidase activity in children treated with valproic acid and carbamazepine.

  Journal of child neurology 20100101

• Production and optimization of valproic acid nanostructured lipid carriers by the Taguchi design.

  Pharmaceutical development and technology 20100101

• Paroxysmal tonic upgaze of childhood and childhood absence epilepsy.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20100101

• Valproic acid-mediated neuroprotection and regeneration in injured retinal ganglion cells.

  Investigative ophthalmology & visual science 20100101

• mRNA expression is a relevant tool to identify developmental neurotoxicants using an in vitro approach.

  Toxicological sciences : an official journal of the Society of Toxicology 20100101

• Ascorbic acid reverses valproic acid-induced inhibition of hoxa2 and maintains glutathione homeostasis in mouse embryos in culture.

  Cellular and molecular neurobiology 20100101

• Histologic and morphologic effects of valproic acid and oxcarbazepine on rat uterine and ovarian cells.

  Epilepsia 20100101

• Nonexploratory movement and behavioral alterations in a thalidomide or valproic acid-induced autism model rat.

  Neuroscience research 20100101

• VPA-related axial skeletal defects and apoptosis: a proposed event cascade.

  Reproductive toxicology (Elmsford, N.Y.) 20100101

• Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.

  Toxicological sciences : an official journal of the Society of Toxicology 20100101

• T2-weighted high-intensity signals in the basal ganglia as an interesting image finding in Unverricht-Lundborg disease.

  Epilepsy research 20100101

• Sodium valproate at the therapeutic concentration inhibits the induction but not the maintenance phase of long-term potentiation in rat hippocampal CA1 area.

  Biochemical and biophysical research communications 20100101

• HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA Double-Strand Break repair capacity.

  Oncology reports 20100101

• Syndrome of inappropriate antidiuretic hormone secretion (SIADH) or hyponatraemia associated with valproic Acid: four case reports from the Netherlands and a case/non-case analysis of vigibase.

  Drug safety 20100101

• Role of antiepileptic drugs as preventive agents for migraine.

  CNS drugs 20100101

• [Ataxia secondary to valproate. The importance of the choice of anti-epileptic treatment in the elderly].

  Revista espanola de geriatria y gerontologia 20100101

• A migraine variant with abdominal colic and Alice in Wonderland syndrome: a case report and review.

  BMC neurology 20100101

• [Neuropsychiatric symptoms caused by valproic acid].

  Revista de neurologia 20100101

• Effects of the antiepileptic drugs on peripheral nerve function.

  Acta neurologica Scandinavica 20100101

• [Lactic acidosis after voluntary intoxication with valproic acid].

  Annales francaises d'anesthesie et de reanimation 20100101

• MeCP2 deficiency downregulates specific nuclear proteins that could be partially recovered by valproic acid in vitro.

  Epigenetics 20100101

• Clinical outcomes and low-dose levocarnitine supplementation in psychiatric inpatients with documented hypocarnitinemia: a retrospective chart review.

  Journal of psychiatric practice 20100101

• Low-dose divalproex in agitated patients with Alzheimer's disease.

  Journal of psychiatric practice 20100101

• [Continuous venovenous haemodiafiltration as a solution for acute intoxication with sodium valproate].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101

• Ethical issues and donor numbers.

  Anaesthesia 20100101

• Psychopharmacological neuroprotection in neurodegenerative disease: assessing the preclinical data.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• [Effect of sodium valproate on aggressive behavior of male mice with various aggression experience].

  Eksperimental'naia i klinicheskaia farmakologiia 20100101

• Antiretroviral intensification and valproic acid lack sustained effect on residual HIV-1 viremia or resting CD4+ cell infection.

  PloS one 20100101

• [Valproate induced hypoactive delirium in a bipolar disorder patient with psychotic features].

  Turk psikiyatri dergisi = Turkish journal of psychiatry 20100101

• Sodium valproate-induced congenital cardiac abnormalities in mice are associated with the inhibition of histone deacetylase.

  Journal of biomedical science 20100101

• [Inappropriate antidiuretic hormone secretion induced by sodium valproate].

  Revue medicale de Liege 20100101

• Conditional downregulation of brain- derived neurotrophic factor and tyrosine kinase receptor B blocks epileptogenesis in the human temporal lobe epilepsy hippocampus.

  Neurology India 20100101

• [Treatment with intravenous valproic acid in a newly born].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101

• [Pharmacokinetics of biological tags in a case of acute valpromide self poisoning].

  Annales de biologie clinique 20100101

• Effect of p-isopropoxyphenylsuccinimide monohydrate on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model.

  Pharmacological reports : PR 20100101

• [Valproic acid induce the expression of MICA antigen in human lung cancer cells and promote the NK killing effects on the cells].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100101

• HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells.

  Molecular cancer 20100101

• Fetal valproate syndrome in a 2-month-old male infant.

  Annals of Saudi medicine 20100101

• Late-onset nocturnal intractable seizure during sleep: what is the origin?

  Medicina (Kaunas, Lithuania) 20100101

• Neuroleptic malignant syndrome following levomepromazine discontinuation.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• [Gollop-Wolfgang Complex in a baby born to an epileptic mother treated with valproic acid during pregnancy].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20100101

• Synthesis and anticonvulsant activity of 4-oxo and 4-thioxo-8-bromobenzopyran derivatives.

  Arzneimittel-Forschung 20100101

• Early predisposition to osteomalacia in Indian adults on phenytoin or valproate monotherapy and effective prophylaxis by simultaneous supplementation with calcium and 25-hydroxy vitamin D at recommended daily allowance dosage: a prospective study.

  Neurology India 20100101

• Somatosensory evoked potentials in epileptic children treated with carbamazepine or valproate in monotherapy - a preliminary study.

  Advances in medical sciences 20100101

• [Efficacy of carbamazepine, valproate and topiramate in the treatment of medial temporal epilepsy in children].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• Epigenetic alterations differ in phenotypically distinct human neuroblastoma cell lines.

  BMC cancer 20100101

• [Comparative efficacy of carbamazepine, valproic acid and topiramate in symptomatic and cryptogenic frontal lobe epilepsy in children].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• Clinical outcomes and immune benefits of anti-epileptic drug therapy in HIV/AIDS.

  BMC neurology 20100101

• Neutrophilic differentiation modulates the apoptotic response of HL-60 cells to sodium butyrate and sodium valproate.

  Neoplasma 20100101

• LICAVAL: combination therapy in acute and maintenance treatment of bipolar disorder.

  Trials 20100101

• Predictors of non-stabilization during the combination therapy of lithium and divalproex in rapid cycling bipolar disorder: a post-hoc analysis of two studies.

  Psychopharmacology bulletin 20100101

• L-carnitine for acute valproic acid overdose: a systematic review of published cases.

  The Annals of pharmacotherapy 20100101

• Misdiagnosis of tuberous sclerosis in a Nigerian girl: a case report and review of literature.

  Annals of African medicine 20100101

• Activities of respiratory chain complexes and citrate synthase influenced by pharmacologically different antidepressants and mood stabilizers.

  Neuro endocrinology letters 20100101

• [Goodpasture's syndrome with neurologic involvement and negative ANCA].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101

• Valproate administered after traumatic brain injury provides neuroprotection and improves cognitive function in rats.

  PloS one 20100101

• Cost effectiveness of adjunctive quetiapine fumarate extended-release tablets with mood stabilizers in the maintenance treatment of bipolar I disorder.

  PharmacoEconomics 20100101

• Pseudotumor cerebri in a patient being treated for bipolar disorder.

  General hospital psychiatry 20100101

• Unexpected interaction between quetiapine and valproate in patients with bipolar disorder.

  General hospital psychiatry 20100101

• The Pott's puffy tumor: an unusual complication of frontal sinusitis, methods for its detection.

  Pediatric dermatology 20100101

• Cell type-specific anti-cancer properties of valproic acid: independent effects on HDAC activity and Erk1/2 phosphorylation.

  BMC cancer 20100101

• Valproic acid transfer across human placental cotyledon during dual perfusion in vitro.

  Annals of agricultural and environmental medicine : AAEM 20100101

• [Mitochondrial recessive ataxia syndrome (MIRAS) and valproate toxicity].

  Duodecim; laaketieteellinen aikakauskirja 20100101

• [Therapeutic drug monitoring of valproate].

  Therapie 20100101

• Valproate induces DNA demethylation in nuclear extracts from adult mouse brain.

  Epigenetics 20100101

• Altering the trajectory of early postnatal cortical development can lead to structural and behavioural features of autism.

  BMC neuroscience 20100101

• A novel explanation for potential toxic effects of valproic acid on creatine: implications for autism.

  Molecular genetics and metabolism 20100101

• Molecular and therapeutic potential and toxicity of valproic acid.

  Journal of biomedicine & biotechnology 20100101

• SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy.

  PloS one 20100101

• Rheumatoid leptomeningitis: radiological alteration of cerebral hypoperfusion and subarachnoid lesions.

  Internal medicine (Tokyo, Japan) 20100101

• A case of schizophrenia with dysphagia successfully treated by a multidimensional approach.

  General hospital psychiatry 20100101

• Drug interaction between carbapenems and extended-release divalproex sodium in a patient with schizoaffective disorder.

  General hospital psychiatry 20100101

• Influence of GABA-acting drugs on morphine-induced hyperthermia in rats.

  Methods and findings in experimental and clinical pharmacology 20100101

• Effect of valproic acid and environmental enrichment on behavioral functions in rats.

  Arzneimittel-Forschung 20100101

• [Malignant migrating partial seizures of infancy: the experience of treatment of status epilepticus in infancy using intravenous valproate--convulex (a clinical case)].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• [Efficacy and safety of intravenous valproates].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• Epigenetic therapy and cisplatin chemoradiation in FIGO stage IIIB cervical cancer.

  European journal of gynaecological oncology 20100101

• [Hemostatic disorders caused by chronic use of valproic acid in neurosurgical patients. Thromboelastographic monitoring].

  Anesteziologiia i reanimatologiia 20100101

• Valproic acid and all trans retinoic acid differentially induce megakaryopoiesis and platelet-like particle formation from the megakaryoblastic cell line MEG-01.

  Platelets 20100101

• Lithium neurotoxicity at normal serum levels.

  The Journal of neuropsychiatry and clinical neurosciences 20100101

• Effects of valproic acid on the cell cycle and apoptosis through acetylation of histone and tubulin in a scirrhous gastric cancer cell line.

  Journal of experimental & clinical cancer research : CR 20100101

• Influence of ethacrynic acid on the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock seizure model.

  Pharmacological reports : PR 20100101

• The effect of a histone deacetylase inhibitor - valproic acid - on nucleoli in human leukaemic myeloblasts.

  Folia biologica 20100101

• The U.S. Food and Drug Adminstration (FDA) has assigned pregnancy category D to valproate.

  North Carolina medical journal 20100101

• Prevention of sodium valproate-induced hepatotoxicity by curcumin, rosiglitazone and N-acetylcysteine in rats.

  Arzneimittel-Forschung 20100101

• [Pharmacokinetic modelling of valproate in epileptic patients].

  Medicinski pregled 20100101

• Inhibition of monoamine oxidase activity by antidepressants and mood stabilizers.

  Neuro endocrinology letters 20100101

• Proliferation and cellular death of A375 cell line in the presence of HDACs inhibitors.

  Acta poloniae pharmaceutica 20100101

• Lamotrigine adjunctive therapy to lithium and divalproex in depressed patients with rapid cycling bipolar disorder and a recent substance use disorder: a 12-week, double-blind, placebo-controlled pilot study.

  Psychopharmacology bulletin 20100101

• [Comparative efficacy of carbamazepine, valproic acid and topiramate in symptomatic and cryptogenic occipital lobe epilepsy in children].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• [Modern conceptions on the status epilepticus and possibilities of treatment with injection form of valproate (convulex)].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101

• Effect of treatment and additional disease on pharmacokinetic of valproic acid in children with epilepsy.

  Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20100101

• Epilepsy (generalised).

  BMJ clinical evidence 20100101

• [Homeostasis of peripheral blood cells during infection by the bovine leukemia virus].

  Bulletin et memoires de l'Academie royale de medecine de Belgique 20100101

• What works for delirious catatonic mania?

  BMJ case reports 20100101

• Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos.

  Blood 20091224

• Modulation of visual cortex excitability in migraine with aura: effects of valproate therapy.

  Neuroscience letters 20091218

• Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20091215

• Valproate reversibly reduces neurite outgrowth by human SY5Y neuroblastoma cells.

  Brain research 20091211

• The influence of drug-drug interaction and patients' characteristics on valproic acid's clearance in adults with epilepsy using nonlinear mixed effects modeling.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091208

• [Antiepileptic drugs for the prevention of pediatric migraine].

  Revue neurologique 20091201

• Folic acid efficacy as an alternative drug added to sodium valproate in the treatment of acute phase of mania in bipolar disorder: a double-blind randomized controlled trial.

  Acta psychiatrica Scandinavica 20091201

• Severe valproic acid intoxication: case study on the unbound fraction and the applicability of extracorporeal elimination.

  European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20091201

• Valproate-associated coagulopathies in children during short-term treatment.

  Journal of child neurology 20091201

• Inhibition of histone deacetylase activity in reduced oxygen environment enhances the osteogenesis of mouse adipose-derived stromal cells.

  Tissue engineering. Part A 20091201

• Life-threatening sodium valproate overdose: a comparison of two approaches to treatment.

  Critical care medicine 20091201

• Idiopathic generalized tonic-clonic epilepsy and photosensitivity: a long-term follow-up study.

  Acta paediatrica (Oslo, Norway : 1992) 20091201

• Antileukemic activity of valproic acid in chronic lymphocytic leukemia B cells defined by microarray analysis.

  Leukemia 20091201

• Valproic acid blocks excitability in SMA type I mouse motor neurons.

  Neurobiology of disease 20091201

• Effects of CYP2C19 and CYP2C9 genotypes on pharmacokinetic variability of valproic acid in Chinese epileptic patients: nonlinear mixed-effect modeling.

  European journal of clinical pharmacology 20091201

• Peroxisome proliferator-activated receptor gamma agonists potentiate the cytotoxic effect of valproic acid in multiple myeloma cells.

  British journal of haematology 20091201

• Introduction of intravenous formulations of the antiepileptic drugs levetiracetam and valproate to the Australian market.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20091201

• Risk factors for valproic acid resistance in childhood absence epilepsy.

  Seizure 20091201

• Effect of valproate on olanzapine plasma concentrations in patients with bipolar or schizoaffective disorder.

  Therapeutic drug monitoring 20091201

• Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy.

  The American journal of psychiatry 20091201

• Once-daily dosing is appropriate for extended-release divalproex over a wide dose range, but not for enteric-coated, delayed-release divalproex: evidence via computer simulations and implications for epilepsy therapy.

  Epilepsy research 20091201

• A prospective study of cognitive fluency and originality in children exposed in utero to carbamazepine, lamotrigine, or valproate monotherapy.

  Epilepsy & behavior : E&B 20091201

• Rhabdomyolysis associated with mania in late life.

  International journal of geriatric psychiatry 20091201

• Inhibition of specific adenylyl cyclase isoforms by lithium and carbamazepine, but not valproate, may be related to their antidepressant effect.

  Bipolar disorders 20091201

• Metabolic alterations during valproic acid treatment: a prospective study.

  Pediatric neurology 20091201

• The effect of carbapenem antibiotics on plasma concentrations of valproic acid.

  The Annals of pharmacotherapy 20091201

• What is the relative value of the standard anticonvulsants: Phenytoin and fosphenytoin, phenobarbital, valproate, and levetiracetam?

  Epilepsia 20091201

• Augmentation of atypical antipsychotics with valproic acid. An open-label study for most difficult patients with schizophrenia.

  Human psychopharmacology 20091201

• Integrated treatment of aggression in the context of ADHD in children refractory to stimulant monotherapy: a window into the future of child psychopharmacology.

  The American journal of psychiatry 20091201

• Valproic acid: long-term effects on children exposed in utero.

  Prescrire international 20091201

• HDAC inhibitor, valproic acid, induces p53-dependent radiosensitization of colon cancer cells.

  Cancer biotherapy & radiopharmaceuticals 20091201

• Acyclic retinoid synergises with valproic acid to inhibit growth in human hepatocellular carcinoma cells.

  Cancer letters 20091128

• Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues.

  Journal of medicinal chemistry 20091126

• [Arm and blood glucose out of control].

  MMW Fortschritte der Medizin 20091126

• Pharmacokinetic interaction between sodium valproate and mycophenolate in renal allograft recipients.

  Transplantation 20091115

• Pedal edema associated with addition of low-dose quetiapine to valproate treatment in bipolar disorder.

  Progress in neuro-psychopharmacology & biological psychiatry 20091113

• Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors.

  Journal of medicinal chemistry 20091112

• Prenatal exposure to valproic acid leads to reduced expression of synaptic adhesion molecule neuroligin 3 in mice.

  Neuroscience 20091110

• Nitric oxide, lipid peroxidation, and antioxidant enzyme levels in epileptic children using valproic acid.

  Brain research 20091110

• Direct hepatic differentiation of mouse embryonic stem cells induced by valproic acid and cytokines.

  World journal of gastroenterology 20091107

• Contraindications to phenytoin in emergency department patients with seizures.

  The Journal of emergency medicine 20091101

• Evaluation of serum lipids and carotid artery intima media thickness in epileptic children treated with valproic acid.

  Brain & development 20091101

• Nonalcoholic fatty liver disease during valproate therapy.

  European journal of pediatrics 20091101

• Enhancement of cisplatin cytotoxicity by SAHA involves endoplasmic reticulum stress-mediated apoptosis in oral squamous cell carcinoma cells.

  Cancer chemotherapy and pharmacology 20091101

• Repeated responses of an elderly patient with high-risk myelodysplastic syndrome to sequential therapy with tipifarnib, 5-azacitidine, and decitabine.

  Annals of hematology 20091101

• Effects of sodium valproate on synaptic transmission and neuronal excitability in rat hippocampus.

  Clinical and experimental pharmacology & physiology 20091101

• Epilepsy in Angelman syndrome: a questionnaire-based assessment of the natural history and current treatment options.

  Epilepsia 20091101

• Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni.

  Molecular and biochemical parasitology 20091101

• Ring chromosome 20 syndrome: a link between epilepsy onset and neuropsychological impairment in three children.

  Epilepsia 20091101

• Diagnostic exercise: sudden death in a mouse with experimentally induced acute myeloid leukemia.

  Veterinary pathology 20091101

• Isobolographic characterization of the anticonvulsant interaction profiles of levetiracetam in combination with clonazepam, ethosuximide, phenobarbital and valproate in the mouse pentylenetetrazole-induced seizure model.

  Seizure 20091101

• Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)-urea.

  European journal of medicinal chemistry 20091101

• Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease.

  Pharmacology, biochemistry, and behavior 20091101

• Is asymmetric dimethylarginine responsible for the vascular events in patients under antiepileptic drug treatment?

  Epilepsy research 20091101

• Early effects of drugs responsible for DRESS on HHV-6 replication in vitro.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20091101

• Valproic acid induces functional heat-shock protein 70 via Class I histone deacetylase inhibition in cortical neurons: a potential role of Sp1 acetylation.

  Journal of neurochemistry 20091101

• Valproic acid plasma concentration decreases in a dose-independent manner following administration of meropenem: a retrospective study.

  Journal of clinical pharmacology 20091101

• Olanzapine-divalproex combination versus divalproex monotherapy in the treatment of bipolar mixed episodes: a double-blind, placebo-controlled study.

  The Journal of clinical psychiatry 20091101

• Epigenetic modulation of PTEN expression during antiandrogenic therapies in human prostate cancer.

  International journal of oncology 20091101

• Valproic acid-induced encephalopathy in very long course treated patients.

  Brain injury 20091101

• Valproic acid intoxication imitating brain death.

  The American journal of emergency medicine 20091101

• Effect of pharmacist participation in the health care team on therapeutic drug monitoring utilization for antiepileptic drugs.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20091101

• Minimally-responsive head injury survivors may have chronic catatonia reversed years after an accident.

  Singapore medical journal 20091101

• The role of divalproex plus olanzapine in outpatient mixed-episode bipolar I disorder.

  The Journal of clinical psychiatry 20091101

• Mixed episodes with psychotic features.

  CNS spectrums 20091101

• Anticonvulsant drugs for pediatric migraine prevention: an evidence-based review.

  European journal of pain (London, England) 20091001

• Long-term antiepileptic drug administration during early life inhibits hippocampal neurogenesis in the developing brain.

  Journal of neuroscience research 20091001

• HDAC2 mediates therapeutic resistance of pancreatic cancer cells via the BH3-only protein NOXA.

  Gut 20091001

• Synthesis, structural analysis and anticonvulsant activity of a ternary Cu(II) mononuclear complex containing 1,10-phenanthroline and the leading antiepileptic drug valproic acid.

  Biochimie 20091001

• Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis.

  Experimental and molecular pathology 20091001

• LBH589 induces up to 10-fold SMN protein levels by several independent mechanisms and is effective even in cells from SMA patients non-responsive to valproate.

  Human molecular genetics 20091001

• Isobolographic characterization of interactions of levetiracetam with the various antiepileptic drugs in the mouse 6 Hz psychomotor seizure model.

  Epilepsy research 20091001

• Lithium attenuates behavioral and biochemical effects of neuropeptide S in mice.

  Peptides 20091001

• Na VPA-induced acute ischemic stroke in an epileptic patient with methylenetetrahydrofolate reductase gene polymorphism.

  Epilepsy research 20091001

• Pharmacologic resuscitation: cell protective mechanisms of histone deacetylase inhibition in lethal hemorrhagic shock.

  The Journal of surgical research 20091001

• Formulations of valproate alter valproate metabolism: a single oral dose kinetic study.

  Therapeutic drug monitoring 20091001

• Overnight versus progressive conversion of multiple daily-dose divalproex to once-daily divalproex extended release: which strategy is better tolerated by adults with intellectual disabilities?

  Journal of clinical psychopharmacology 20091001

• Valproic acid toxicity associated with low dose of aspirin and low total valproic acid levels: a case report.

  Journal of clinical psychopharmacology 20091001

• Is the brain arachidonic acid cascade a common target of drugs used to manage bipolar disorder?

  Biochemical Society transactions 20091001

• PtdIns(3,4,5)P(3) and inositol depletion as a cellular target of mood stabilizers.

  Biochemical Society transactions 20091001

• Valproic acid- and lithium-sensitivity in prs mutants of Saccharomyces cerevisiae.

  Biochemical Society transactions 20091001

• Structure-function studies for the panacea, valproic acid.

  Biochemical Society transactions 20091001

• Investigation of the H(+)-myo-inositol transporter (HMIT) as a neuronal regulator of phosphoinositide signalling.

  Biochemical Society transactions 20091001

• Sodium valproate: an old drug with new roles.

  Trends in pharmacological sciences 20091001

• [Aetiology of epileptic seizures in a rehabilitation centre].

  Revista de neurologia 20091001

• Combination treatment with quetiapine in bipolar disorder patients.

  The American journal of psychiatry 20091001

• Unilateral lung agenesis: coincidence or association with maternal valproate therapy?

  Journal of paediatrics and child health 20091001

• Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.

  Birth defects research. Part B, Developmental and reproductive toxicology 20091001

• [Use of antiepileptic drugs for the preventive treatment of migraine].

  Brain and nerve = Shinkei kenkyu no shinpo 20091001

• Cerebrotendinous xanthomatosis: a treatable neurodegenerative disease.

  The Journal of the Association of Physicians of India 20091001

• Chitosan may decrease serum valproate and increase the risk of seizure reappearance.

  BMJ (Clinical research ed.) 20090924

• Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.

  Oncogene 20090903

• Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial.

  Journal of psychopharmacology (Oxford, England) 20090901

• The influence of valproic acid treatment on hair and serum zinc levels and serum biotinidase activity.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20090901

• High prevalence of metabolic disturbances in patients with bipolar disorder in Taiwan.

  Journal of affective disorders 20090901

• Analysis of neuroprotective effects of valproic acid on primary motor neurons in monoculture or co-cultures with astrocytes or Schwann cells.

  Cellular and molecular neurobiology 20090901

• Epigenetic influences on sensory regeneration: histone deacetylases regulate supporting cell proliferation in the avian utricle.

  Journal of the Association for Research in Otolaryngology : JARO 20090901

• Staff and patient views of the reasons for aggressive incidents: a prospective, incident-based study.

  The Psychiatric quarterly 20090901

• Efficacy of anti-epileptic drugs in patients with gliomas and seizures.

  Journal of neurology 20090901

• The risk of asymptomatic hyperammonemia in children with idiopathic epilepsy treated with valproate: relationship to blood carnitine status.

  Epilepsy research 20090901

• Valproic acid induces up- or down-regulation of gene expression responsible for the neuronal excitation and inhibition in rat cortical neurons through its epigenetic actions.

  Neuroscience research 20090901

• Pregnancy, delivery, and outcome for the child in maternal epilepsy.

  Epilepsia 20090901

• Epigenetic control of sexual differentiation of the bed nucleus of the stria terminalis.

  Endocrinology 20090901

• Fatal intoxication with naftidrofuryl.

  Legal medicine (Tokyo, Japan) 20090901

• Evidence supporting a role for endoplasmic reticulum stress in the development of atherosclerosis in a hyperglycaemic mouse model.

  Antioxidants & redox signaling 20090901

• Migrainous vertigo responsive to intravenous methylprednisolone: case reports.

  Headache 20090901

• Histone deacetylase-2 is a key regulator of diabetes- and transforming growth factor-beta1-induced renal injury.

  American journal of physiology. Renal physiology 20090901

• MLH1 protects from resistance acquisition by the histone deacetylase inhibitor trichostatin A in colon tumor cells.

  International journal of oncology 20090901

• Simultaneous treatment with camptothecin and valproic acid suppresses induction of Bcl-X(L) and promotes apoptosis of MCF-7 breast cancer cells.

  Apoptosis : an international journal on programmed cell death 20090901

• Reversible effects of antiepileptic drugs on thyroid hormones in men and women with epilepsy: a prospective randomized double-blind withdrawal study.

  Epilepsy & behavior : E&B 20090901

• An initial report of a new biological marker for bipolar disorder: P85 evoked brain potential.

  Bipolar disorders 20090901

• New evidence that an epigenetic mechanism mediates testosterone-dependent brain masculinization.

  Endocrinology 20090901

• The first line of therapy in a girl with juvenile myoclonic epilepsy: should it be valproate or a new agent?

  Epilepsia 20090901

• Use of a new antiepileptic drug or an old one as first drug for treatment of absence epilepsy.

  Epilepsia 20090901

• Rational polytherapy.

  Epilepsia 20090901

• Pregnancy treatment guidelines: throwing the baby out with the bath water.

  Epilepsia 20090901

• Angiotensin II induces cardiomyocyte hypertrophy probably through histone deacetylases.

  The Tohoku journal of experimental medicine 20090901

• Predictors and prognosis of status epilepticus treated with intravenous sodium valproate.

  Epileptic disorders : international epilepsy journal with videotape 20090901

• [Correlation between renal tubular dysfunction and serum carnitine deficiency in cases with valproate therapy].

  No to hattatsu = Brain and development 20090901

• Abnormal bleeding or bruising associated with antieplieptic treatment.

  Current drug safety 20090901

• A single-dose, three-period, six-sequence crossover study comparing the bioavailability of solution, suspension, and enteric-coated tablets of magnesium valproate in healthy Mexican volunteers under fasting conditions.

  Clinical therapeutics 20090901

• Differential effects of valproic acid on growth, proliferation and metastasis in HTB5 and HTB9 bladder cancer cell lines.

  Cancer letters 20090828

• Histone deacetylase inhibitors promote neurosteroid-mediated cell differentiation and enhance serotonin-stimulated brain-derived neurotrophic factor gene expression in rat C6 glioma cells.

  Journal of neuroscience research 20090815

• Preliminary evidence on the association between XBP1-116C/G polymorphism and response to prophylactic treatment with valproate in bipolar disorders.

  Psychiatry research 20090815

• Histone deacetylase inhibitors as anti-neoplastic agents.

  Cancer letters 20090808

• Cognitive function after fetal exposure to antiepileptic drugs.

  The New England journal of medicine 20090806

• The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo.

  Journal of cellular and molecular medicine 20090801

• Induction of hepatic differentiation of mouse bone marrow stromal stem cells by the histone deacetylase inhibitor VPA.

  Journal of cellular and molecular medicine 20090801

• Rowell's syndrome in the course of treatment with sodium valproate: a case report and review of the literature data.

  Clinical and experimental dermatology 20090801

• Valproic acid blocks adhesion of renal cell carcinoma cells to endothelium and extracellular matrix.

  Journal of cellular and molecular medicine 20090801

• Sodium butyrate upregulates expression of NKG2D ligand MICA/B in HeLa and HepG2 cell lines and increases their susceptibility to NK lysis.

  Cancer immunology, immunotherapy : CII 20090801

• Impact on survival of different treatments for myelodysplastic syndromes (MDS).

  Leukemia research 20090801

• Is survival enough for myelodysplastic syndromes?

  Leukemia research 20090801

• Mood stabilizers increase prepulse inhibition in DBA/2NCrl mice.

  Psychopharmacology 20090801

• Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study.

  Epilepsy research 20090801

• Efficacy and safety of levetiracetam in the treatment of Panayiotopoulos syndrome.

  Epilepsy research 20090801

• Effects of valproic acid on sleep in children with epilepsy.

  Epilepsia 20090801

• Effects of levetiracetam and valproate on reproductive endocrine function studied in human ovarian follicular cells.

  Epilepsia 20090801

• Valproate-related peripheral oedema: a manageable but probably neglected condition.

  The international journal of neuropsychopharmacology 20090801

• Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice.

  Current cancer drug targets 20090801

• Human decidual stromal cells protect lymphocytes from apoptosis.

  Placenta 20090801

• Poor applicability of estimation method for adults to calculate unbound serum concentrations of valproic acid in epileptic neonates and infants.

  Journal of clinical pharmacy and therapeutics 20090801

• Divalproex sodium in children with partial seizures: 12-month safety study.

  Pediatric neurology 20090801

• Valproic acid-induced myopathy in a patient with schizoaffective disorder.

  Journal of clinical psychopharmacology 20090801

• Deletion mutants of AP-1 adaptin subunits display distinct phenotypes in fission yeast.

  Genes to cells : devoted to molecular & cellular mechanisms 20090801

• Surviving blood loss without blood transfusion in a swine poly-trauma model.

  Surgery 20090801

• Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090801

• Extracorporeal elimination in acute valproic acid poisoning.

  Clinical toxicology (Philadelphia, Pa.) 20090801

• Epilepsy: Should valproate be avoided during childbearing years?

  Nature reviews. Neurology 20090801

• Rational treatment options with AEDs and ketogenic diet in Landau-Kleffner syndrome: still waiting after all these years.

  Epilepsia 20090801

• Unilateral eyelid angiofibroma with complete blepharoptosis as the presenting sign of tuberous sclerosis.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20090801

• Acute valproic acid overdose: enhance elimination with multiple-doses activated charcoal.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090801

• [Valproic acid versus lamotrigine as a monotherapy for absence epilepsy in children].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20090801

• Wicket spikes misinterpreted as focal abnormalities in idiopathic generalized epilepsy with prescription of carbamazepine leading to paradoxical aggravation.

  Neurophysiologie clinique = Clinical neurophysiology 20090801

• Randomized sequential trial of valproic acid in amyotrophic lateral sclerosis.

  Annals of neurology 20090801

• Divalproex is not effective for children with bipolar disorder.

  The Harvard mental health letter 20090801

• Genotype-phenotype studies in infantile spinal muscular atrophy (SMA) type I in Germany: implications for clinical trials and genetic counselling.

  Clinical genetics 20090801

• Comparison of treatment effect of sodium valproate, propranolol and tricyclic antidepressants in migraine.

  Pakistan journal of biological sciences : PJBS 20090801

• Valproic acid-inducible Arl4D and cytohesin-2/ARNO, acting through the downstream Arf6, regulate neurite outgrowth in N1E-115 cells.

  Experimental cell research 20090715

• Practice parameter update: management issues for women with epilepsy--focus on pregnancy (an evidence-based review): teratogenesis and perinatal outcomes: report of the Quality Standards Subcommittee and Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and American Epilepsy Society.

  Neurology 20090714

• Valproate preparations for agitation in dementia.

  The Cochrane database of systematic reviews 20090708

• Traditional Chinese medicine for epilepsy.

  The Cochrane database of systematic reviews 20090708

• Sodium valproate, a histone deacetylase inhibitor, decreases the secretion of soluble Fas by human osteosarcoma cells and increases their sensitivity to Fas-mediated cell death.

  Journal of cancer research and clinical oncology 20090701

• Medical and substance use comorbidity in bipolar disorder.

  Journal of affective disorders 20090701

• Common effects of lithium and valproate on mitochondrial functions: protection against methamphetamine-induced mitochondrial damage.

  The international journal of neuropsychopharmacology 20090701

• Anti-leukemic activity of valproic acid and imatinib mesylate on human Ph+ ALL and CML cells in vitro.

  European journal of haematology 20090701

• A riluzole- and valproate-sensitive persistent sodium current contributes to the resting membrane potential and increases the excitability of sympathetic neurones.

  Pflugers Archiv : European journal of physiology 20090701

• Hyperammonemia following intravenous valproate loading.

  Epilepsy research 20090701

• Retinal ganglion cell toxicity due to oxcarbazepine and valproic acid treatment in rat.

  Seizure 20090701

• Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity.

  Molecular and cellular neurosciences 20090701

• N-(anilinomethyl)-p-isopropoxyphenylsuccinimide potentiates the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock-induced seizure model.

  Neuroscience research 20090701

• [Mood stabilizer in the psychopharmacotherapy of borderline personality disorder].

  Fortschritte der Neurologie-Psychiatrie 20090701

• Valproic acid in pregnancy: how much are we endangering the embryo and fetus?

  Reproductive toxicology (Elmsford, N.Y.) 20090701

• Effectiveness of the first antiepileptic drug in the treatment of pediatric epilepsy.

  Pediatric neurology 20090701

• Stupor and fast activity on electroencephalography in a child treated with valproate.

  Pediatric neurology 20090701

• Migraine, valproic acid, and lipoprotein(a).

  Pediatric neurology 20090701

• Cognitive outcome after exposure to antiepileptic drugs in utero.

  The Lancet. Neurology 20090701

• [The role of the neuromodulators in the preventive treatment of migraine].

  Revista de neurologia 20090701

• A cocaine body packer case report: clinical and forensic aspects.

  Clinical toxicology (Philadelphia, Pa.) 20090701

• Translation of randomised controlled trial findings into clinical practice: comparison of olanzapine and valproate in the EMBLEM study.

  Pharmacopsychiatry 20090701

• Development of extended release divalproex sodium tablets containing hypdrophobic and hydrophilic matrix.

  Current drug delivery 20090701

• Headspace solid-phase microextraction-gas chromatography method for the determination of valproic acid in human serum, and formulations using hollow-fiber coated wire.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090701

• A case of fetal valproate syndrome with new features expanding the phenotype.

  Saudi medical journal 20090701

• Once daily monotherapy with prolonged-release valproate minitablets given in the evening--a chronopharmacological study.

  International journal of clinical pharmacology and therapeutics 20090701

• The relationship between glucuronide conjugate levels and hepatotoxicity after oral administration of valproic acid.

  Archives of pharmacal research 20090701

• Acute renal failure following detergent ingestion.

  Singapore medical journal 20090701

• Brain amyloidoma with cerebral hemorrhage.

  The Journal of the American Osteopathic Association 20090701

• Clinical roundtable monograph. Combination therapies for MDS.

  Clinical advances in hematology & oncology : H&O 20090701

• Topiramate in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register.

  Neurology 20090609

• Speech-activated myoclonus masquerading as stuttering.

  Neurology 20090602

• Effective prophylactic therapy for cyclic vomiting syndrome in children using valproate.

  Brain & development 20090601

• The effects of biotin supplementation on serum and liver tissue biotinidase enzyme activity and alopecia in rats which were administrated to valproic acid.

  Brain & development 20090601

• Renal medullary effects of transient prehypertensive treatment in young spontaneously hypertensive rats.

  Acta physiologica (Oxford, England) 20090601

• A subset of patients with high-risk acute myelogenous leukemia shows improved peripheral blood cell counts when treated with the combination of valproic acid, theophylline and all-trans retinoic acid.

  Leukemia research 20090601

• Seizure control and side-effect profile after switching adult epileptic patients from standard to extended-release divalproex sodium.

  Clinical neurology and neurosurgery 20090601

• Histone deacetylase inhibitors and candidate gene expression: An in vivo and in vitro approach to studying chromatin remodeling in a clinical population.

  Journal of psychiatric research 20090601

• Cluster attacks responsive to recreational cannabis and dronabinol.

  Headache 20090601

• Commentary to: 'Evaluation of serum lipids and carotid artery intima media thickness in epileptic children treated with valproic acid'.

  Brain & development 20090601

• The supra-additive hyperactivity caused by an amphetamine-chlordiazepoxide mixture exhibits an inverted-U dose response: negative implications for the use of a model in screening for mood stabilizers.

  Pharmacology, biochemistry, and behavior 20090601

• Changing trends in antiepileptic drug prescribing in girls of child-bearing potential.

  Archives of disease in childhood 20090601

• An increased risk of road traffic accidents after prescriptions of lithium or valproate?

  Pharmacoepidemiology and drug safety 20090601

• Cocaine-induced hyperactivity and sensitization are dependent on GSK3.

  Neuropharmacology 20090601

• Dose-dependent memory effects and cerebral volume changes after in utero exposure to valproate in the rat.

  Epilepsia 20090601

• Valproate treatment and cocaine cue reactivity in cocaine dependent individuals.

  Drug and alcohol dependence 20090601

• Common increase of GATA-3 level in PC-12 cells by three teratogens causing autism spectrum disorders.

  Neuroscience research 20090601

• Fungal pleural effusion secondary to a rare cause of pancreatic pseudocyst.

  Pediatric pulmonology 20090601

• A double-blind randomized trial of mood stabilizer augmentation using lamotrigine and valproate for patients with schizophrenia who are stabilized and partially responsive.

  Journal of clinical psychopharmacology 20090601

• Eosinophilic pleural effusion associated with the addition of sodium valproate.

  Journal of clinical psychopharmacology 20090601

• Histone deacetylase inhibitors induce a very broad, pleiotropic anticancer drug resistance phenotype in acute myeloid leukemia cells by modulation of multiple ABC transporter genes.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090601

• Observation of fetal brain in a rat valproate-induced autism model: a developmental neurotoxicity study.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090601

• [Hyperammonaemic encephalopathy due to valproic acid in the neonatal period].

  Revista de neurologia 20090601

• Cancer risk in long-term users of valproate: a population-based case-control study.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090601

• Which is the best anti-convulsant drug for the treatment of epilepsy in psoriatic or other Th1 mediated skin disease patients?

  Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20090601

• Posterior reversible encephalopathy syndrome posttransplantation: a case report of possible association with cerebrospinal fluid leak after epidural catheterization.

  Transplantation proceedings 20090601

• Can lithium or valproate untie tangles in Alzheimer's disease?

  The Journal of clinical psychiatry 20090601

• Adding lithium or anticonvulsants to antipsychotics for the treatment of schizophrenia: useful strategy or exercise in futility?

  The Journal of clinical psychiatry 20090601

• Acute pancreatitis associated to the use of valproic acid.

  Arquivos de neuro-psiquiatria 20090601

• Cost-effectiveness of quetiapine plus mood stabilizers compared with mood stabilizers alone in the maintenance therapy of bipolar I disorder: results of a Markov model analysis.

  Clinical therapeutics 20090601

• New antiepileptic drugs: molecular targets.

  Central nervous system agents in medicinal chemistry 20090601

• [Valproate-meropenem co-administration, an example of information shortcomings in relevant drug interactions].

  Medicina clinica 20090530

• A novel system allowing long-term simultaneous video-electroencephalography recording, drug infusion and blood sampling in rats.

  Journal of neuroscience methods 20090515

• Is valproate promising in cardiac fatal arrhythmias? Comparison of P- and Q-wave dispersion in bipolar affective patients on valproate or lithium-valproate maintenance therapy with healthy controls.

  Journal of psychopharmacology (Oxford, England) 20090501

• States of serum leptin and insulin in children with epilepsy: risk predictors of weight gain.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20090501

• Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090501

• Conversion from valproic acid onto topiramate in adolescents and adults with epilepsy.

  Acta neurologica Scandinavica 20090501

• Lithium increases synapse formation between hippocampal neurons by depleting phosphoinositides.

  Molecular pharmacology 20090501

• Infantile spasms and Down syndrome: a new animal model.

  Pediatric research 20090501

• A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents.

  Journal of the American Academy of Child and Adolescent Psychiatry 20090501

• Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon.

  Nature methods 20090501

• Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin.

  International journal of oncology 20090501

• Life-threatening organ failure after lamotrigine therapy.

  Pediatric neurology 20090501

• Valproate-induced reversible pseudoatrophy of the brain and hyperammonemic encephalopathy in a bipolar patient.

  The Australian and New Zealand journal of psychiatry 20090501

• Variation in glucuronidation of lamotrigine in human liver microsomes.

  Xenobiotica; the fate of foreign compounds in biological systems 20090501

• Evaluating the incidence of leukopenia and neutropenia with valproate, quetiapine, or the combination in children and adolescents.

  The Annals of pharmacotherapy 20090501

• Acquired von Willebrand syndrome as side effect of valproic acid therapy in children is rare.

  Hamostaseologie 20090501

• A review of valproate in psychiatric practice.

  Expert opinion on drug metabolism & toxicology 20090501

• Valproate activates the Notch3/c-FLIP signaling cascade: a strategy to attenuate white matter hyperintensities in bipolar disorder in late life?

  Bipolar disorders 20090501

• Management issues for women with epilepsy-Focus on pregnancy (an evidence-based review): II. Teratogenesis and perinatal outcomes: Report of the Quality Standards Subcommittee and Therapeutics and Technology Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

  Epilepsia 20090501

• [Recent advances in DNA demethylation in tumor therapy].

  Zhonghua bing li xue za zhi = Chinese journal of pathology 20090501

• [Inadequate vasopressin secretion and valproate].

  Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20090501

• [Limbic encephalitis associated to voltage dependent potassium channel antibodies: report of one case].

  Revista medica de Chile 20090501

• Alpha-fluoro-2,2,3,3-tetramethylcyclopropanecarboxamide, a novel potent anticonvulsant derivative of a cyclic analogue of valproic acid.

  Journal of medicinal chemistry 20090423

• Cognitive function at 3 years of age after fetal exposure to antiepileptic drugs.

  The New England journal of medicine 20090416

• Valproic acid enhances bosutinib cytotoxicity in colon cancer cells.

  International journal of cancer 20090415

• Valproate, in combination with pemetrexed and cisplatin, provides additional efficacy to the treatment of malignant mesothelioma.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090415

• Valproic acid delayed release (Stavzor).

  The Medical letter on drugs and therapeutics 20090406

• The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement.

  Molecular psychiatry 20090401

• A study on epileptic negative myoclonus in atypical benign partial epilepsy of childhood.

  Brain & development 20090401

• Development of hippocampal sclerosis after a complex febrile seizure.

  European journal of pediatrics 20090401

• Effects of valproate on the dopaminergic system in mice.

  Neurological research 20090401

• Divalproex ER combined with olanzapine or risperidone for treatment of acute exacerbations of schizophrenia.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20090401

• Acetazolamide reversibly inhibits water conduction by aquaporin-4.

  Journal of structural biology 20090401

• Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate.

  Leukemia 20090401

• Bone metabolism alteration on antiepileptic drug therapy.

  Indian journal of pediatrics 20090401

• Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, diminishes lymphoproliferation in the Fas -deficient MRL/lpr(-/-) murine model of autoimmune lymphoproliferative syndrome (ALPS).

  Experimental hematology 20090401

• [Drugs for status epilepticus treatment].

  Revue neurologique 20090401

• Lamotrigine and valproic acid have different effects on motorcortical neuronal excitability.

  Journal of neural transmission (Vienna, Austria : 1996) 20090401

• Intravenous sodium valproate in mainland China for the treatment of diazepam refractory convulsive status epilepticus.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20090401

• Na+,K+-ATPase activity in an animal model of mania.

  Journal of neural transmission (Vienna, Austria : 1996) 20090401

• Effects of epilepsy and valproic acid on oxidant status in children with idiopathic epilepsy.

  Epilepsy research 20090401

• Genetic basis for idiosyncratic reactions to antiepileptic drugs.

  Current opinion in neurology 20090401

• Alternative treatments in pediatric bipolar disorder.

  Child and adolescent psychiatric clinics of North America 20090401

• Maintenance treatment for patients with bipolar I disorder: results from a north american study of quetiapine in combination with lithium or divalproex (trial 127).

  The American journal of psychiatry 20090401

• Long-term dietary administration of valproic acid does not affect, while retinoic acid decreases, the lifespan of G93A mice, a model for amyotrophic lateral sclerosis.

  Muscle & nerve 20090401

• Potentiation of a topoisomerase I inhibitor, karenitecin, by the histone deacetylase inhibitor valproic acid in melanoma: translational and phase I/II clinical trial.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090401

• Clinical and biological effects of valproic acid as a histone deacetylase inhibitor on tumor and surrogate tissues: phase I/II trial of valproic acid and epirubicin/FEC.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090401

• Comparative efficacy and safety of oxcarbazepine versus divalproex sodium in the treatment of acute mania: a pilot study.

  European psychiatry : the journal of the Association of European Psychiatrists 20090401

• An experimental design for finding of minimum dosage of carbamazepine and valproate in preventing of seizure attacks.

  Pakistan journal of pharmaceutical sciences 20090401

• Correspondence on 'Lipid profile, apolipoproteins A and B in children with epilepsy''.

  Journal of child neurology 20090401

• Valproic acid enhances protein L-isoaspartyl methyltransferase expression by stimulating extracellular signal-regulated kinase signaling pathway.

  Neuropharmacology 20090401

• Valproic acid causes dose- and time-dependent changes in nuclear structure in prostate cancer cells in vitro and in vivo.

  Molecular cancer therapeutics 20090401

• [Reversed effect of valproic acid on transcription inhibition of AML1-ETO fusion protein of kasumi-1 leukemic cell line].

  Zhongguo shi yan xue ye xue za zhi 20090401

• Effects of a dopamine receptor agonist and atropine sulfate on absorption of valproic acid in rats.

  Biomedical research (Tokyo, Japan) 20090401

• Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: a prospective randomized study.

  Epilepsy & behavior : E&B 20090401

• Youngest patient with Sydenham's chorea: a case report.

  Journal of the Indian Medical Association 20090401

• Aripiprazole-induced sialorrhea.

  Progress in neuro-psychopharmacology & biological psychiatry 20090317

• Valproate and lamotrigine level variation with menstrual cycle phase and oral contraceptive use.

  Neurology 20090310

• Association of MDR1 C3435T polymorphism with bipolar disorder in patients treated with valproic acid.

  Molecular biology reports 20090301

• Comparison of add-on valproate and primidone in carbamazepine-unresponsive patients with partial epilepsy.

  Seizure 20090301

• Synergistic induction of NY-ESO-1 antigen expression by a novel histone deacetylase inhibitor, valproic acid, with 5-aza-2'-deoxycytidine in glioma cells.

  Journal of neuro-oncology 20090301

• Lamotrigine-valproic acid combination therapy for medically refractory epilepsy.

  Epilepsia 20090301

• An adult onset patient with Kleine-Levin syndrome responding to valproate.

  Sleep medicine 20090301

• Epstein-Barr virus episome stability is coupled to a delay in replication timing.

  Journal of virology 20090301

• Schistosoma mansoni: developmental arrest of miracidia treated with histone deacetylase inhibitors.

  Experimental parasitology 20090301

• Effects of mood stabilizers on brain reward processes in rats: studies using the intracranial self-stimulation paradigm.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090301

• Expression of mitochondrial complex I subunit gene NDUFV2 in the lymphoblastoid cells derived from patients with bipolar disorder and schizophrenia.

  Neuroscience research 20090301

• Valproic acid-induced deregulation in vitro of genes associated in vivo with neural tube defects.

  Toxicological sciences : an official journal of the Society of Toxicology 20090301

• Valproic acid activates the PI3K/Akt/mTOR pathway in muscle and ameliorates pathology in a mouse model of Duchenne muscular dystrophy.

  The American journal of pathology 20090301

• Valproate-induced metabolic changes in patients with epilepsy: assessment with H-MRS.

  Epilepsia 20090301

• Management of diabetic neuropathy by sodium valproate and glyceryl trinitrate spray: a prospective double-blind randomized placebo-controlled study.

  Diabetes research and clinical practice 20090301

• Weight gain in children treated with valproate.

  Journal of child neurology 20090301

• [Empirical evidence for the use of anticonvulsants in personality disorders].

  Fortschritte der Neurologie-Psychiatrie 20090301

• Drug treatment of epilepsy in the century of the ILAE: the second 50 years, 1959-2009.

  Epilepsia 20090301

• [Effect of valproic acid on the expression of P27(Kip1) and P170 and drug resistance of HL-60/HT cells].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090301

• Confusion, a rather serious adverse drug reaction with valproic acid: a review of the French Pharmacovigilance database.

  Pharmacopsychiatry 20090301

• Charles Bonnet syndrome disappearing with carbamazepine and valproic acid but not with levetiracetam.

  Acta neurologica Belgica 20090301

• [Reversible dementia-like condition and parkinsonism in an elderly woman. Idiosyncratic adverse effects connected to 11 years of antiepileptic medication].

  Lakartidningen 20090301

• Evaluation of the effects of propylisopropylacetic acid (PIA) on neuronal growth cone morphology.

  Neuropharmacology 20090301

• Bone morphogenetic protein 4 stimulates neuronal differentiation of neuronal stem cells through the ERK pathway.

  Experimental & molecular medicine 20090227

• The neuroprotective action of the mood stabilizing drugs lithium chloride and sodium valproate is mediated through the up-regulation of the homeodomain protein Six1.

  Toxicology and applied pharmacology 20090215

• Refractory restless legs syndrome likely caused by olanzapine.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20090215

• Influence of polymeric subcoats on the drug release properties of tablets powder-coated with pre-plasticized Eudragit L 100-55.

  International journal of pharmaceutics 20090209

• Identification of novel targets for PGC-1alpha and histone deacetylase inhibitors in neuroblastoma cells.

  Biochemical and biophysical research communications 20090206

• Valproic acid as a therapeutic agent for head and neck squamous cell carcinomas.

  Cancer chemotherapy and pharmacology 20090201

• Evidence for involvement of ERK, PI3K, and RSK in induction of Bcl-2 by valproate.

  Journal of molecular neuroscience : MN 20090201

• Effect of antiepileptic drug polytherapy on urinary pH in children and young adults.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20090201

• Isobolographic characterization of interactions of retigabine with carbamazepine, lamotrigine, and valproate in the mouse maximal electroshock-induced seizure model.

  Naunyn-Schmiedeberg's archives of pharmacology 20090201

• Histone acetylation resulting in resistance to methotrexate in choroid plexus cells.

  Journal of neuro-oncology 20090201

• GSK3beta modulates PACAP-induced neuritogenesis in PC12 cells by acting downstream of Rap1 in a caveolae-dependent manner.

  Cellular signalling 20090201

• Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation.

  Neuropharmacology 20090201

• Combination therapy with histone deacetylase inhibitors and lithium chloride: a novel treatment for carcinoid tumors.

  Annals of surgical oncology 20090201

• Elevated FOSB-expression; a potential marker of valproate sensitivity in AML.

  British journal of haematology 20090201

• Valproic acid enhances the engraftability of human umbilical cord blood hematopoietic stem cells expanded under serum-free conditions.

  European journal of haematology 20090201

• Moclobemide monotherapy vs. combined therapy with valproic acid or carbamazepine in depressive patients: a pharmacokinetic interaction study.

  British journal of clinical pharmacology 20090201

• Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling.

  Trends in pharmacological sciences 20090201

• Rapid detection of drugs in biofluids using atmospheric pressure chemi/chemical ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20090201

• First-drug treatment failures in children newly diagnosed with epilepsy.

  Pediatric neurology 20090201

• Thrombophilic risk factors in epileptic children treated with valproic Acid.

  Pediatric neurology 20090201

• The effect of constipation on valproic acid dosage in a 17-year-old.

  Pediatric neurology 20090201

• Effects of the histone deacetylase inhibitor valproic acid on the sensitivity of anaplastic thyroid cancer cell lines to imatinib.

  Oncology reports 20090201

• Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice.

  Cancer research 20090201

• Notch1 mediates growth suppression of papillary and follicular thyroid cancer cells by histone deacetylase inhibitors.

  Molecular cancer therapeutics 20090201

• A case of fetal valproate syndrome with new features expanding the phenotype.

  Saudi medical journal 20090201

• [Meropenem and valproic acid. An interaction to remember].

  Anales de pediatria (Barcelona, Spain : 2003) 20090201

• Diagnosis and management of the primary headache disorders in the emergency department setting.

  Emergency medicine clinics of North America 20090201

• Effect of divalproex on brain morphometry, chemistry, and function in youth at high-risk for bipolar disorder: a pilot study.

  Journal of child and adolescent psychopharmacology 20090201

• Long-term safety of divalproex sodium extended-release in children and adolescents with bipolar I disorder.

  Journal of child and adolescent psychopharmacology 20090201

• Carnitine in the treatment of valproic acid-induced toxicity.

  Clinical toxicology (Philadelphia, Pa.) 20090201

• Effect of concomitant administration of meropenem and valproic acid in an elderly Chinese patient.

  The American journal of geriatric pharmacotherapy 20090201

• Schizencephaly associated with bipolar II disorder.

  Singapore medical journal 20090201

• [Cognitive impairment and parkinsonism due to use of sodium valproate].

  Tijdschrift voor gerontologie en geriatrie 20090201

• Unrecognized valproic acid intoxication.

  The American journal of emergency medicine 20090201

• Chronic dietary administration of valproic acid protects neurons of the rat nucleus basalis magnocellularis from ibotenic acid neurotoxicity.

  Neurotoxicity research 20090201

• Valproic acid induces transcriptional activation of human GD3 synthase (hST8Sia I) in SK-N-BE(2)-C human neuroblastoma cells.

  Molecules and cells 20090131

• Interstimulus interval (ISI) discrimination of the conditioned eyeblink response in a rodent model of autism.

  Behavioural brain research 20090123

• Transcriptional regulation of cholesterol 24-hydroxylase by histone deacetylase inhibitors.

  Biochemical and biophysical research communications 20090123

• Olanzapine in long-term treatment for bipolar disorder.

  The Cochrane database of systematic reviews 20090121

• [Valproate treatment during pregnancy: description of four cases with foetal valproate syndrome].

  Ugeskrift for laeger 20090119

• A phase I-II study of the histone deacetylase inhibitor valproic acid plus chemoimmunotherapy in patients with advanced melanoma.

  British journal of cancer 20090113

• Valproic acid regulates catecholaminergic pathways by concentration-dependent threshold effects on TH mRNA synthesis and degradation.

  Brain research 20090109

• Ethylbutyrate, a valproate-like compound, exhibits inositol-depleting effects--a potential mood-stabilizing drug.

  Life sciences 20090102

• The mood stabilizers lithium and valproate selectively activate the promoter IV of brain-derived neurotrophic factor in neurons.

  Molecular psychiatry 20090101

• A case of catatonia resembling frontotemporal dementia and resolved with electroconvulsive therapy.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

• Synthesis and potential anticonvulsant activity of new N-3-substituted 5,5-cyclopropanespirohydantoins.

  European journal of medicinal chemistry 20090101

• Complete protection of sodium valproate from humidity by using a hydrotalcite composite.

  Journal of pharmaceutical sciences 20090101

• Hippocampal remodelling after MDMA neurotoxicity: a single case study.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

• Unilateral rubral tremor following treatment with risperidone.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

• Revised Korean medication algorithm for bipolar disorder.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

• Familial hemiplegic migraine with prolonged aura and multimodality imaging: a case report.

  Headache 20090101

• New thinking in the development of novel derivatization reagents for liquid chromatography-mass spectrometric detection.

  Biomedical chromatography : BMC 20090101

• Enhanced clearance of highly protein-bound drugs by albumin-supplemented dialysate during modeled continuous hemodialysis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090101

• Epigenetic reprogramming of breast cancer cells by valproic acid occurs regardless of estrogen receptor status.

  The international journal of biochemistry & cell biology 20090101

• Effect of aging on glucuronidation of valproic acid in human liver microsomes and the role of UDP-glucuronosyltransferase UGT1A4, UGT1A8, and UGT1A10.

  Drug metabolism and disposition: the biological fate of chemicals 20090101

• Valproic acid increases CXCR4 expression in hematopoietic stem/progenitor cells by chromatin remodeling.

  Stem cells and development 20090101

• Thyroid function in children with epilepsy treated with sodium valproate monotherapy: a prospective study.

  Clinical neuropharmacology 20090101

• Yeast bioassay for identification of inositol depleting compounds.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

• Thyroid hormones in children with epilepsy during long-term administration of carbamazepine and valproate.

  European journal of endocrinology 20090101

• Multiple linear sclerodermas with a diffuse Parry-Romberg syndrome.

  Joint, bone, spine : revue du rhumatisme 20090101

• Patterns of antiepileptic drug overdose differ between men and women: admissions to the Edinburgh Poisons Unit, 2000-2007.

  QJM : monthly journal of the Association of Physicians 20090101

• Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells.

  British journal of haematology 20090101

• Early effects of sodium valproate monotherapy on serum paraoxonase/arylesterase activities.

  Scandinavian journal of clinical and laboratory investigation 20090101

• Safety and tolerability of divalproex sodium extended-release in the prophylaxis of migraine headaches: results of an open-label extension trial in adolescents.

  Headache 20090101

• Divalproex sodium extended-release for the prophylaxis of migraine headache in adolescents: results of a stand-alone, long-term open-label safety study.

  Headache 20090101

• Fibular aplasia in a child exposed to sodium valproate in pregnancy.

  Clinical dysmorphology 20090101

• Functional outcomes in first-episode patients with bipolar disorder: a prospective study from the Systematic Treatment Optimization Program for Early Mania project.

  Comprehensive psychiatry 20090101

• Body mass index and serum lipid changes during treatment with valproic acid in children with epilepsy.

  The Annals of pharmacotherapy 20090101

• Comparison of insulin resistance, metabolic syndrome and adiponectin in overweight bipolar patients taking sodium valproate and controls.

  The Australian and New Zealand journal of psychiatry 20090101

• Successful treatment of anaplastic thyroid carcinoma with a combination of oral valproic acid, chemotherapy, radiation and surgery.

  Endocrine journal 20090101

• Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma.

  International journal of hematology 20090101

• Valproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase kinase-3 in lesion development and hepatic steatosis.

  The American journal of pathology 20090101

• Extreme elevation of creatinine phosphokinase levels in neuroleptic malignant syndrome associated with atypical antipsychotics.

  The American journal of psychiatry 20090101

• Valproate, a mood stabilizer, induces WFS1 expression and modulates its interaction with ER stress protein GRP94.

  PloS one 20090101

• A case with Stevens Johnson syndrome triggered by combination of clobazam, lamotrigine, and valproic acid treatment.

  International journal of dermatology 20090101

• [The contribution of magnetic resonance imaging to the diagnosis of type I glutaric aciduria].

  Revista de neurologia 20090101

• Improvement of obsessive-compulsive disorder with divalproex and lamotrigine in two patients with bipolar II disorder.

  Pharmacopsychiatry 20090101

• Serum and muscle carnitine levels in epileptic children receiving sodium valproate.

  Journal of child neurology 20090101

• [Case of juvenile myoclonic epilepsy misdiagnosed as simple partial seizure for more than 60 years].

  Brain and nerve = Shinkei kenkyu no shinpo 20090101

• Valproate-induced insulin resistance and obesity in children.

  Hormone research 20090101

• A 6-month, double-blind, maintenance trial of lithium monotherapy versus the combination of lithium and divalproex for rapid-cycling bipolar disorder and Co-occurring substance abuse or dependence.

  The Journal of clinical psychiatry 20090101

• 'Nother one for Narcan.

  JEMS : a journal of emergency medical services 20090101

• Long-term effects of valproic acid on reproductive endocrine functions in Turkish women with epilepsy.

  Gynecologic and obstetric investigation 20090101

• Effects of divalproex sodium on hemoglobin level.

  Blood cells, molecules & diseases 20090101

• [Valproic acid induced intracellular GSH-redox imbalance and apoptosis of leukemic cells resistant to dexamethasone and doxorubicin].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20090101

• [When a seizure occurs...].

  Revue medicale de Liege 20090101

• A possible utilization of the mice forced swim test for modeling manic-like increase in vigor and goal-directed behavior.

  Journal of pharmacological and toxicological methods 20090101

• Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves.

  Advances in medical sciences 20090101

• Reproductive and metabolic abnormalities associated with bipolar disorder and its treatment.

  Harvard review of psychiatry 20090101

• A preliminary controlled trial of divalproex in posttraumatic stress disorder.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20090101

• Unusual cutaneous reaction with sodium valproate.

  Neurology India 20090101

• Phase II open label study of valproic acid in spinal muscular atrophy.

  PloS one 20090101

• Assessment of embryotoxicity using mouse embryo culture.

  Methods in molecular biology (Clifton, N.J.) 20090101

• [Fetal malformations in women with epilepsy].

  Akusherstvo i ginekologiia 20090101

• Divalproex sodium-induced eosinophilic pleural effusion.

  American journal of therapeutics 20090101

• Differences in immunolocalization of Kim-1, RPA-1, and RPA-2 in kidneys of gentamicin-, cisplatin-, and valproic acid-treated rats: potential role of iNOS and nitrotyrosine.

  Toxicologic pathology 20090101

• Transcription-independent heritability of induced histone modifications in the mouse preimplantation embryo.

  PloS one 20090101

• Differential effects of antiepileptic drugs on steroidogenesis in a human in vitro cell model.

  Acta neurologica Scandinavica. Supplementum 20090101

• Metabolomics study with gas chromatography-mass spectrometry for predicting valproic acid-induced hepatotoxicity and discovery of novel biomarkers in rat urine.

  International journal of toxicology 20090101

• Managing agitation associated with traumatic brain injury: behavioral versus pharmacologic interventions?

  PM & R : the journal of injury, function, and rehabilitation 20090101

• Anticonvulsants in the treatment of major depressive disorder: an overview.

  Harvard review of psychiatry 20090101

• Lamotrigine and valproate pharmacokinetics interactions in epileptic patients.

  European journal of drug metabolism and pharmacokinetics 20090101

• Myelination in bipolar patients and the effects of mood stabilizers on brain anatomy.

  Current pharmaceutical design 20090101

• Quantifying in vivo phosphoinositide turnover in chemotactically competent Dictyostelium cells.

  Methods in molecular biology (Clifton, N.J.) 20090101

• Cost-effectiveness of quetiapine with lithium or divalproex for maintenance treatment of bipolar I disorder.

  Journal of medical economics 20090101

• Valproate-induced delirium in a demented patient.

  Archives of gerontology and geriatrics 20090101

• [Juvenile myoclonic epilepsy with recurrent myoclonic status: efficacy of valproate].

  Therapie 20090101

• Sodium valproate and the fetus: a case study and review of the literature.

  Neonatal network : NN 20090101

• [Parkinsonism due to the medication].

  Nederlands tijdschrift voor geneeskunde 20090101

• Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level.

  BMC neuroscience 20090101

• Valproate-induced hyperammonemic encephalopathy and normal liver functions: possible synergism with topiramate.

  Clinical neuropharmacology 20090101

• Frequency of and rationales for the combined use of electroconvulsive therapy and antiepileptic drugs in Austria and the literature.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

• Face-related ictal hallucinations and illusions and reflex-type phenomena.

  The Journal of neuropsychiatry and clinical neurosciences 20090101

• Analytical interference of carbamazepine on the Abbott TDx and Abbott Axsym tricyclic antidepressant assays.

  Pathology 20090101

• [Effects of valproate on male reproductive functions].

  Turk psikiyatri dergisi = Turkish journal of psychiatry 20090101

• Biochemical, molecular and epigenetic mechanisms of valproic acid neuroprotection.

  Current molecular pharmacology 20090101

• [Open randomized comparative twelve-week study of lithium and valproate in manic episode].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101

• [Homocysteine and asymmetric dimethylarginine (ADMA) in epilepsy].

  Przeglad lekarski 20090101

• [The original nootropic and neuroprotective drug noopept potentiates the anticonvulsant activity of valproate in mice].

  Eksperimental'naia i klinicheskaia farmakologiia 20090101

• Aplasia cutis congenita: three cases with three different underlying etiologies.

  The Turkish journal of pediatrics 20090101

• Fetal sodium valproate exposure causes Baller-Gerold syndrome phenotype: both phenotypes in the same family.

  The Turkish journal of pediatrics 20090101

• Onychomadesis: a rare side-effect of valproic acid medication?

  Pediatric dermatology 20090101

• How the NOTCH pathway contributes to the ability of osteosarcoma cells to metastasize.

  Cancer treatment and research 20090101

• Valproate and neuroprotective effects for bipolar disorder.

  International review of psychiatry (Abingdon, England) 20090101

• Lithium and valproate and their possible effects on themyo-inositol second messenger system in healthy volunteers and bipolar patients.

  International review of psychiatry (Abingdon, England) 20090101

• Valproic acid-carbapenem interaction: report of six cases and a review of the literature.

  Drug metabolism and drug interactions 20090101

• [Pathogenetic basis of pharmaceutical hepatitis induced by depakine in children].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101

• Catatonia and CPK elevation in neurosyphilis: role of plural pharmacodynamic mechanisms.

  Psychopharmacology bulletin 20090101

• [Acute childhood pancreatitis caused by valproate].

  Lijecnicki vjesnik 20090101

• Pisa syndrome and parkinsonism secondary to valproic acid in Huntington's disease.

  Movement disorders : official journal of the Movement Disorder Society 20081215

• Additive effects of histone deacetylase inhibitors and amphetamine on histone H4 acetylation, cAMP responsive element binding protein phosphorylation and DeltaFosB expression in the striatum and locomotor sensitization in mice.

  Neuroscience 20081202

• New histone deacetylase inhibitors as potential therapeutic tools for advanced prostate carcinoma.

  Journal of cellular and molecular medicine 20081201

• Adiponectin receptor R1 is upregulated by valproic acid but not by topiramate in human hepatoma cell line, HepG2.

  Seizure 20081201

• Valproate teratogenicity and epilepsy syndrome.

  Epilepsia 20081201

• Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons.

  The international journal of neuropsychopharmacology 20081201

• Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma.

  Journal of neuro-oncology 20081201

• Valproic acid attenuates inflammation in experimental autoimmune neuritis.

  Cellular and molecular life sciences : CMLS 20081201

• A review of the preclinical and clinical evidence for protein kinase C as a target for drug development for bipolar disorder.

  Current psychiatry reports 20081201

• Epileptic disorders in pregnancy: an overview.

  Current opinion in obstetrics & gynecology 20081201

• Comparison between lithium and valproate in the treatment of acute mania.

  Journal of clinical psychopharmacology 20081201

• Methylphenidate in attention deficit hyperactivity disorder and bipolar disorder.

  Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20081201

• Histone deacetylase inhibitors upregulate Notch-1 and inhibit growth in pheochromocytoma cells.

  Surgery 20081201

• Adjunctive medication effects may increase risk for neutropenia.

  The American journal of psychiatry 20081201

• Septo-optic dysplasia and psychiatric disorders: a case report.

  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20081201

• Life-threatening valproate overdose successfully treated with haemodialysis.

  Arhiv za higijenu rada i toksikologiju 20081201

• Population pharmacokinetics of valproate in Mexican children with epilepsy.

  Biopharmaceutics & drug disposition 20081201

• Stuttering as a side-effect of divalproex sodium.

  Psychiatry and clinical neurosciences 20081201

• Comparison of the effectiveness of topiramate and sodium valproate in pediatric migraine.

  Journal of child neurology 20081201

• The role of the newer antiepileptic drugs in the treatment of generalized convulsive status epilepticus.

  Epilepsia 20081201

• The incidence and characteristics of clozapine- induced fever in a local psychiatric unit in Hong Kong.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20081201

• Influence of NMDA and non-NMDA antagonists on acute and inflammatory pain in the trigeminal territory: a placebo control study.

  Arquivos de neuro-psiquiatria 20081201

• [Synergistic effects of VPA and As2O3 on Molt-4 cells in vitro and its possible mechanisms].

  Zhongguo shi yan xue ye xue za zhi 20081201

• Non-life-threatening leukopenia in a renal transplant recipient with acute overdose of mycophenolate mofetil.

  Transplantation proceedings 20081201

• A pilot pharmacotherapy trial for depressed youths at high genetic risk for bipolarity.

  Journal of child and adolescent psychopharmacology 20081201

• [Catatonic syndrome associated with mixed bipolar disorder: a case report and therapeutic considerations].

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20081201

• [Gilles de la Tourette syndrome in a child with bipolar disorder].

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20081201

• Persistence with migraine prophylactic treatment and acute migraine medication utilization in the managed care setting.

  Clinical therapeutics 20081201

• [Inhibitory effect of valproic acid on cell cycle of Kasumi-1 cell line and its mechanism].

  Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20081201

• Valproic acid related idiosyncratic drug induced hepatotoxicity in a glioblastoma patient treated with temozolomide.

  Acta neurologica Belgica 20081201

• Decreased valproate level caused by VPA-glucuronidase inhibition by carbapenem antibiotics.

  Drug metabolism letters 20081201

• Treatment-emergent mania/hypomania during antidepressant monotherapy in patients with rapid cycling bipolar disorder.

  Bipolar disorders 20081201

• A two-site ELISA can quantify upregulation of SMN protein by drugs for spinal muscular atrophy.

  Neurology 20081125

• Linking SMN to SMA: an assay for the rescuer.

  Neurology 20081125

• A mutation in the calreticulin gene promoter in a family case of schizoaffective disorder leads to its aberrant transcriptional activation.

  Brain research 20081106

• Proteomic analysis of peripheral leukocytes in Alzheimer's disease patients treated with divalproex sodium.

  Neurobiology of aging 20081101

• Changes in outpatient lithium treatment in the Netherlands during 1996-2005.

  Journal of affective disorders 20081101

• Agmatine enhances the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock seizure model.

  Journal of neural transmission (Vienna, Austria : 1996) 20081101

• Chronic administration of valproic acid reduces brain NMDA signaling via arachidonic acid in unanesthetized rats.

  Neurochemical research 20081101

• Treatment emergent mania responding to valproate in a Chinese female adolescent population with eating disorders: a case series.

  European eating disorders review : the journal of the Eating Disorders Association 20081101

• Photocarcinogenesis of topical tazarotene and isotretinoin alone and in combination with valproic acid in hairless mice.

  Experimental dermatology 20081101

• Investigation of the drug-drug interaction between alpha-lipoic acid and valproate via mitochondrial beta-oxidation.

  Pharmaceutical research 20081101

• Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.

  Epilepsy research 20081101

• Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice.

  Journal of molecular medicine (Berlin, Germany) 20081101

• Dose-finding study with nicotine as a proconvulsant agent in PTZ-induced seizure model in mice.

  Journal of biomedical science 20081101

• Treatment of status epilepticus and acute repetitive seizures with i.v. valproic acid vs phenytoin.

  Acta neurologica Scandinavica 20081101

• Use of hemodialysis and hemoperfusion in poisoned patients.

  Kidney international 20081101

• Demethylating agents in myeloid malignancies.

  Current opinion in oncology 20081101

• Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.

  Nature biotechnology 20081101

• Quantitative assessment of postoperative blood collection in brain tumor surgery under valproate medication.

  Zentralblatt fur Neurochirurgie 20081101

• Mood stabilizer loading versus titration in acute mania: audit of clinical practice.

  The Australian and New Zealand journal of psychiatry 20081101

• Effect of a manually generated laboratory comment on requesting and performance of valproate assays.

  Journal of clinical pathology 20081101

• Television-provoked epilepsy in children: a follow-up survey from Isfahan, Iran.

  Archives of Iranian medicine 20081101

• Prescription patterns of psychotropic medications in elderly compared with younger participants who achieved a 'recovered' status in the systematic treatment enhancement program for bipolar disorder.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20081101

• A multiple-loop, double-cube microarray design applied to prostate cancer cell lines with variable sensitivity to histone deacetylase inhibitors.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081101

• Effects of mood stabilizers on DNA damage in an animal model of mania.

  Journal of psychiatry & neuroscience : JPN 20081101

• Lipid profile, apolipoproteins A and B in children with epilepsy.

  Journal of child neurology 20081101

• Altered morphology of motor cortex neurons in the VPA rat model of autism.

  Developmental psychobiology 20081101

• In vivo anti-myeloma activity and modulation of gene expression profile induced by valproic acid, a histone deacetylase inhibitor.

  British journal of haematology 20081101

• Involvement of PML nuclear bodies in CBP degradation through the ubiquitin-proteasome pathway.

  Epigenetics 20081101

• Olanzapine versus divalproex versus placebo in the treatment of mild to moderate mania: a randomized, 12-week, double-blind study.

  The Journal of clinical psychiatry 20081101

• Valproate induced non hepatic hyperammonaemic encephalopathy (VNHE)--a study from tertiary care referral university hospital, north India.

  JPMA. The Journal of the Pakistan Medical Association 20081101

• A comparison of cognitive functioning in medicated and unmedicated subjects with bipolar depression.

  Bipolar disorders 20081101

• The role of epilepsy in early language development in a child with a congenital lesion in the right hemisphere.

  Developmental medicine and child neurology 20081101

• [Valproic acid induced-idiosyncratic hepatotoxicity].

  Anales de pediatria (Barcelona, Spain : 2003) 20081101

• Valproic acid and all-trans retinoic acid: meta-analysis of a palliative treatment regimen in AML and MDS patients.

  Onkologie 20081101

• Pharmacokinetic modeling of carbamazepine based on clinical data from Serbian epileptic patients.

  Methods and findings in experimental and clinical pharmacology 20081101

• Detection of human survival motor neuron (SMN) protein in mice containing the SMN2 transgene: applicability to preclinical therapy development for spinal muscular atrophy.

  Journal of neuroscience methods 20081030

• Valproic acid induces polarization, neuronal-like differentiation of a subpopulation of C6 glioma cells and selectively regulates transgene expression.

  Neuroscience 20081028

• Event related oscillations in euthymic patients with bipolar disorder.

  Neuroscience letters 20081017

• Brain oscillatory responses in patients with bipolar disorder manic episode before and after valproate treatment.

  Brain research 20081015

• DNA topoisomerase I inhibitors ameliorate seizure-like behaviors and paralysis in a Drosophila model of epilepsy.

  Neuroscience 20081015

• Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes.

  FEBS letters 20081015

• Paliperidone as a mood stabilizer: a pre-frontal cortex synaptoneurosomal proteomics comparison with lithium and valproic acid after chronic treatment reveals similarities in protein expression.

  Brain research 20081003

• Efficacy of adjunctive aripiprazole to either valproate or lithium in bipolar mania patients partially nonresponsive to valproate/lithium monotherapy: a placebo-controlled study.

  The American journal of psychiatry 20081001

• Increase in antiepileptic efficacy during prolonged treatment with valproic acid: role of inhibition of histone deacetylases?

  Epilepsy research 20081001

• Time to rehospitalization in patients with bipolar I disorder on lithium or valproate with adjunctive antipsychotics.

  Psychopharmacology 20081001

• [Dementia syndrome in an elderly subject related to valproic acid use: a case report].

  La Revue de medecine interne 20081001

• Transport of valproate at intestinal epithelial (Caco-2) and brain endothelial (RBE4) cells: mechanism and substrate specificity.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20081001

• Up-regulation of protein L-isoaspartyl methyltransferase expression by lithium is mediated by glycogen synthase kinase-3 inactivation and beta-catenin stabilization.

  Neuropharmacology 20081001

• Lamotrigine might potentiate valproic acid-induced hyperammonemic encephalopathy.

  Progress in neuro-psychopharmacology & biological psychiatry 20081001

• Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency.

  Journal of cellular biochemistry 20081001

• Antiepileptic drug utilization in children from 1997-2005--a study from the Netherlands.

  European journal of clinical pharmacology 20081001

• Delayed-onset neutropenia with divalproex sodium.

  The Annals of pharmacotherapy 20081001

• Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives.

  Bioorganic & medicinal chemistry 20081001

• The association between carbamazepine and valproate and adverse cutaneous drug reactions in patients with bipolar disorder: a nested matched case-control study.

  Journal of clinical psychopharmacology 20081001

• Efficacy of quetiapine monotherapy in rapid-cycling bipolar disorder in comparison with sodium valproate.

  Journal of clinical psychopharmacology 20081001

• Phase I study of epigenetic modulation with 5-azacytidine and valproic acid in patients with advanced cancers.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20081001

• Bipolar drug development: are we getting closer to the real world?

  The American journal of psychiatry 20081001

• Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy.

  Journal of clinical pharmacy and therapeutics 20081001

• [Reversible Parkinsonism and cognitive impairment following treatment with valproate].

  Revista de neurologia 20081001

• [Posterior reversible leukoencephalopathy in a patient with postpartum eclampsia].

  Medicina intensiva 20081001

• Trichotillomania: a case of response to valproic acid.

  Journal of child and adolescent psychopharmacology 20081001

• Effect of phenytoin and valproic acid therapy on serum lipid levels and liver function tests.

  Indian pediatrics 20081001

• Hemicrania continua evolving from cluster headache responsive to valproic acid.

  Headache 20081001

• Polycystic ovary syndrome in women using valproate: a review.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20081001

• [Hyperammoniemia and central pontine myelinolysis in a patient with Sjögren syndrome and chronic valproate use].

  Recenti progressi in medicina 20081001

• [Molecular genetic basis of proximal spinal muscular atrophy and experience in its pharmaceutical treatment].

  Genetika 20081001

• Valproate-induced hyperammonemic encephalopathy.

  Pediatrics and neonatology 20081001

• Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation.

  Proceedings of the National Academy of Sciences of the United States of America 20080909

• CNS depressant and anticonvulsant activities of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.

  European journal of medicinal chemistry 20080901

• Going up in smoke: tobacco smoking is associated with worse treatment outcomes in mania.

  Journal of affective disorders 20080901

• Regulation of ER alpha signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90.

  Neurochemical research 20080901

• Quetiapine and classical mood stabilizers in the long-term treatment of Bipolar Disorder: a 4-year follow-up naturalistic study.

  Journal of affective disorders 20080901

• Simultaneous toxicities in a child on multiple anticonvulsants.

  Journal of child neurology 20080901

• Gene expression analysis in absence epilepsy using a monozygotic twin design.

  Epilepsia 20080901

• Valproic acid: a viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures.

  Biotechnology and bioengineering 20080901

• Valproic acid inhibits the growth of cervical cancer both in vitro and in vivo.

  Journal of biochemistry 20080901

• DNA hypermethylation and epigenetic silencing of the tumor suppressor gene, SLC5A8, in acute myeloid leukemia with the MLL partial tandem duplication.

  Blood 20080901

• Solid-state forms of sodium valproate, active component of the anticonvulsant drug epilim.

  ChemMedChem 20080901

• Specificity of the Toxoplasma gondii-altered behaviour to definitive versus non-definitive host predation risk.

  Parasitology 20080901

• Histone deacetylase inhibitors augment antitumor efficacy of herpes-based oncolytic viruses.

  Molecular therapy : the journal of the American Society of Gene Therapy 20080901

• Tetramethylcyclopropyl analogue of the leading antiepileptic drug, valproic acid: evaluation of the teratogenic effects of its amide derivatives in NMRI mice.

  Birth defects research. Part A, Clinical and molecular teratology 20080901

• Enantioselective formation of ibuprofen-S-acyl-glutathione in vitro in incubations of ibuprofen with rat hepatocytes.

  Chemical research in toxicology 20080901

• Valproate and babies.

  The Australian and New Zealand journal of psychiatry 20080901

• Modulation of adhesion and growth of colon and pancreatic cancer cells by the histone deacetylase inhibitor valproic acid.

  International journal of molecular medicine 20080901

• A 12-week, open, randomized trial comparing sodium valproate to lithium in patients with bipolar I disorder suffering from a manic episode.

  International clinical psychopharmacology 20080901

• Clonally expanded mitochondrial DNA mutations in epileptic individuals with mutated DNA polymerase gamma.

  Journal of neuropathology and experimental neurology 20080901

• Valproic acid-mediated transcriptional regulation of human GM3 synthase (hST3Gal V) in SK-N-BE(2)-C human neuroblastoma cells.

  Acta pharmacologica Sinica 20080901

• Lack of valproic acid-associated weight gain in prepubertal children.

  Pediatric neurology 20080901

• Postradiation sensitization of the histone deacetylase inhibitor valproic acid.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20080901

• Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock.

  The Journal of trauma 20080901

• [The effect of prophylactic therapy with valproate sodium and phenobarbital in two patients with cyclic vomiting syndrome].

  No to hattatsu = Brain and development 20080901

• Association of lamotrigine and valproate in refractory epilepsies of children and adolescents.

  Arquivos de neuro-psiquiatria 20080901

• Does ghrelin really increase in epileptic children treated with valproate?

  Journal of child neurology 20080901

• [Anticonvulsant mood stabilizers in the treatment of behavioral and psychological symptoms of dementia (BPSD)].

  L'Encephale 20080901

• Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency.

  Nature neuroscience 20080901

• Combined lithium and valproate treatment delays disease onset, reduces neurological deficits and prolongs survival in an amyotrophic lateral sclerosis mouse model.

  Neuroscience 20080826

• Mixed models for ordinal data: a pharmacokinetic study on the effectiveness of drug for the reduction of epileptic seizures.

  Statistics in medicine 20080815

• Current status of epigenetic treatment in myelodysplastic syndromes.

  Annals of hematology 20080801

• Histone deacetylase inhibitors and a functional potent inhibitory effect on human uterine contractility.

  American journal of obstetrics and gynecology 20080801

• CSF monoamine metabolites and neuropeptides in depressed patients before and after electroconvulsive therapy.

  European psychiatry : the journal of the Association of European Psychiatrists 20080801

• Effect of valproic acid treatment on body composition, leptin and the soluble leptin receptor in epileptic children.

  Epilepsy research 20080801

• Oxcarbazepine and valproic acid-induced lupus in a 7-year-old boy.

  Acta paediatrica (Oslo, Norway : 1992) 20080801

• Inverse correlation of valproic acid serum concentrations and quality of life in adolescents with epilepsy.

  Epilepsy research 20080801

• Estimating the effects of co-medications on plasma olanzapine concentrations by using a mixed model.

  Progress in neuro-psychopharmacology & biological psychiatry 20080801

• Efficacy and safety of quetiapine in combination with lithium or divalproex for maintenance of patients with bipolar I disorder (international trial 126).

  Journal of affective disorders 20080801

• Valproic acid poisoning: an evidence-based consensus guideline for out-of-hospital management.

  Clinical toxicology (Philadelphia, Pa.) 20080801

• Valproate: do formulations matter?

  Journal of clinical pharmacy and therapeutics 20080801

• Modest reactivation of the mutant FMR1 gene by valproic acid is accompanied by histone modifications but not DNA demethylation.

  Pharmacogenetics and genomics 20080801

• Toxic interaction between valproate and oxcarbazepine: a case detected by the free valproate level.

  Journal of clinical psychopharmacology 20080801

• Anticonvulsant activity of some xanthone derivatives.

  Bioorganic & medicinal chemistry 20080801

• Cell protective mechanism of valproic acid in lethal hemorrhagic shock.

  Surgery 20080801

• Sustained-release valproate in partial epilepsy: comparison between VIPe and Gulf VIPe study findings.

  European journal of neurology 20080801

• Perspectives on interactions between antiepileptic drugs (AEDs) and antimicrobial agents.

  Epilepsia 20080801

• Hyperandrogenism, ovulatory dysfunction, and polycystic ovary syndrome with valproate versus lamotrigine.

  Annals of neurology 20080801

• Early intervention in bipolar disorder, part II: therapeutics.

  Early intervention in psychiatry 20080801

• Differentiating human NT2/D1 neurospheres as a versatile in vitro 3D model system for developmental neurotoxicity testing.

  Toxicology 20080730

• Clinically relevant concentrations of valproic acid modulate melatonin MT(1) receptor, HDAC and MeCP2 mRNA expression in C6 glioma cells.

  European journal of pharmacology 20080728

• Valproate for schizophrenia.

  The Cochrane database of systematic reviews 20080716

• A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts.

  Cell cycle (Georgetown, Tex.) 20080715

• Age-related differences in susceptibility to toxic effects of valproic acid in rats.

  Journal of applied toxicology : JAT 20080701

• The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models.

  Epilepsia 20080701

• Effects of chronic treatment with valproate and oxcarbazepine on ovarian folliculogenesis in rats.

  Epilepsia 20080701

• Valproate affects reproductive endocrine function, testis diameter and some semen variables in non-epileptic adolescent goat bucks.

  Theriogenology 20080701

• Gender-specific behavioral and immunological alterations in an animal model of autism induced by prenatal exposure to valproic acid.

  Psychoneuroendocrinology 20080701

• Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.

  Epilepsia 20080701

• Fish liver oil and propolis as protective natural products against the effect of the anti-epileptic drug valproate on immunological markers of bone formation in rats.

  Epilepsy research 20080701

• Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin.

  Experimental cell research 20080701

• Valproate-induced parkinsonism, glial cells and Alexander's disease.

  Progress in neuro-psychopharmacology & biological psychiatry 20080701

• Risks versus benefits of valproic acid?

  Fertility and sterility 20080701

• Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.

  Nature biotechnology 20080701

• Valproic acid induces Notch1 signaling in small cell lung cancer cells.

  The Journal of surgical research 20080701

• Status epilepticus in central nervous system infections: an experience from a developing country.

  The American journal of medicine 20080701

• [Eclampsia at a teaching hospital in Ivory Coast: management, outcome and prognostic factors].

  Canadian journal of anaesthesia = Journal canadien d'anesthesie 20080701

• Perinatal depression: treatment options and dilemmas.

  Journal of psychiatry & neuroscience : JPN 20080701

• Bioequivalence studies of a new valproic acid delayed-release capsule and divalproex sodium delayed-release tablet.

  Current medical research and opinion 20080701

• High incidence of vaproate-induced coagulation disorders in children receiving valproic acid: a prospective study.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20080701

• Outcome in West syndrome.

  Indian pediatrics 20080701

• Synthesis and anticonvulsant evaluation of 6-amino-1,4-oxazepane-3,5-dione derivatives.

  Archives of pharmacal research 20080701

• Divalproex extended-release in adolescent migraine prophylaxis: results of a randomized, double-blind, placebo-controlled study.

  Headache 20080701

• Teratogenicity of antiepileptic medications.

  Seminars in neurology 20080701

• Prolonged valproic acid treatment does not reduce the size of latent HIV reservoir.

  AIDS (London, England) 20080619

• Valproic acid without intensified antiviral therapy has limited impact on persistent HIV infection of resting CD4+ T cells.

  AIDS (London, England) 20080619

• Psychiatric use and utility of divalproex sodium in Connecticut prisons.

  International journal of offender therapy and comparative criminology 20080601

• Approaches to mitochondrially mediated cancer therapy.

  Seminars in cancer biology 20080601

• Effect of melatonin and melatonylvalpromide on beta-amyloid and neurofilaments in N2a cells.

  Neurochemical research 20080601

• Valproic acid extends Caenorhabditis elegans lifespan.

  Aging cell 20080601

• Neuroactive steroids, mood stabilizers, and neuroplasticity: alterations following lithium and changes in Bcl-2 knockout mice.

  The international journal of neuropsychopharmacology 20080601

• Valproate-dependent transcriptional regulation of GLAST/EAAT1 expression: involvement of Ying-Yang 1.

  Neurochemistry international 20080601

• Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?

  Molecular psychiatry 20080601

• Levetiracetam as monotherapy or add-on to valproate in the treatment of acute mania-a randomized open-label study.

  Psychopharmacology 20080601

• Attention changes in epilepsy patients following 3-month topiramate or valproate treatment revealed by event-related potential.

  International journal of psychophysiology : official journal of the International Organization of Psychophysiology 20080601

• An in vivo [18F]MK-9470 microPET study of type 1 cannabinoid receptor binding in Wistar rats after chronic administration of valproate and levetiracetam.

  Neuropharmacology 20080601

• Valproic acid resensitizes cisplatin-resistant ovarian cancer cells.

  Cancer science 20080601

• Opsoclonus-myoclonus-ataxia syndrome with autoantibodies to glutamic acid decarboxylase.

  Clinical neurology and neurosurgery 20080601

• Neuronal peroxisome proliferator-activated receptor gamma signaling: regulation by mood-stabilizer valproate.

  Journal of molecular neuroscience : MN 20080601

• An adult case of cyclic vomiting syndrome successfully responding to valproic acid.

  Journal of neurology 20080601

• Synthesis and anticonvulsant activity of aromatic tetramethylcyclopropanecarboxamide derivatives.

  Bioorganic & medicinal chemistry 20080601

• A case of hyperammonemic encephalopathy after 11 years of valproate therapy.

  Journal of clinical psychopharmacology 20080601

• Valproic acid activity in androgen-sensitive and -insensitive human prostate cancer cells.

  International journal of oncology 20080601

• Valproic acid activates Notch1 signaling and induces apoptosis in medullary thyroid cancer cells.

  Annals of surgery 20080601

• Factor VII deficiency associated with valproate treatment.

  Pediatrics international : official journal of the Japan Pediatric Society 20080601

• Targeting cancer and neuropathy with histone deacetylase inhibitors: two birds with one stone?

  Current cancer drug targets 20080601

• [Sodium valproate synergizes adriamycin to inhibit proliferation and induce apoptosis in myelodysplastic syndrome cell line].

  Zhongguo shi yan xue ye xue za zhi 20080601

• [Influence of age, body weight and dose on sodium valproate plasma concentrations in children with epilepsy].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080601

• Atypical depression as a premonitory symptom of migraine managed by an oral contraceptive.

  Psychiatry and clinical neurosciences 20080601

• Anticonvulsants to treat idiopathic restless legs syndrome: systematic review.

  Arquivos de neuro-psiquiatria 20080601

• Oral divalproex sodium loading for adolescent outpatients with acute mania/hypomania: a report of 2 cases.

  The Journal of clinical psychiatry 20080601

• Health-related quality of life in Thai bipolar disorder.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20080601

• Adjunctive lamotrigine for partial seizures in patients aged 1 to 24 months.

  Neurology 20080527

• Valproic acid for the treatment of myeloid malignancies.

  Cancer 20080515

• Hepatic encephalopathy precipitated by sodium valproate therapy.

  The Medical journal of Australia 20080505

• [Lithium intoxications at normal serum levels].

  Psychiatrische Praxis 20080501

• Histone deacetylase inhibitors induce TAP, LMP, Tapasin genes and MHC class I antigen presentation by melanoma cells.

  Cancer immunology, immunotherapy : CII 20080501

• Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARalpha.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080501

• Encephalopathy induced by levetiracetam added to valproate.

  Acta neurologica Scandinavica 20080501

• Valproic acid as epigenetic cancer drug: preclinical, clinical and transcriptional effects on solid tumors.

  Cancer treatment reviews 20080501

• The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans.

  Molecular biology of the cell 20080501

• Neuroendocrine transdifferentiation induced by VPA is mediated by PPARgamma activation and confers resistance to antiblastic therapy in prostate carcinoma.

  The Prostate 20080501

• Pediatric bipolar disorder: evidence-based psychopharmacological treatments.

  Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc 20080501

• Acute effects of N-(2-propylpentanoyl)urea on hippocampal amino acid neurotransmitters in pilocarpine-induced seizure in rats.

  Epilepsy research 20080501

• [Hyperammonaemic encephalopathy due to valproic acid].

  Revista de neurologia 20080501

• Reversible neutrophil abnormalities related to supratherapeutic valproic acid levels.

  Mayo Clinic proceedings 20080501

• [Novel therapeutic strategy for neurogenesis in the neurodegenerative disorders].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080501

• Enhanced rat sciatic nerve regeneration through silicon tubes implanted with valproic acid.

  Journal of reconstructive microsurgery 20080501

• Indications.

  Journal of psychiatric practice 20080501

• Comparative clinical responses to risperidone and divalproex in patients with pediatric bipolar disorder.

  Journal of psychiatric practice 20080501

• Epigenetic disregulation induces cell growth retardation in primary cultured glial cells.

  Journal of bioscience and bioengineering 20080501

• Antiepileptic drugs and thyroid function.

  Journal of pediatric endocrinology & metabolism : JPEM 20080501

• Bone health in young women with epilepsy after one year of antiepileptic drug monotherapy.

  Neurology 20080429

• VPA-induced apoptosis and behavioral deficits in neonatal mice.

  Brain research 20080408

• Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.

  Neuroscience letters 20080404

• Histone deacetylase inhibitors trichostatin A and valproic acid induce cell cycle arrest and p21 expression in immortalized human endometrial stromal cells.

  European journal of obstetrics, gynecology, and reproductive biology 20080401

• Effects of lithium and valproate on serum and hippocampal neurotrophin-3 levels in an animal model of mania.

  Journal of psychiatric research 20080401

• Plasma and cerebrospinal fluid pharmacokinetics of valproic acid after oral administration in non-human primates.

  Cancer chemotherapy and pharmacology 20080401

• Hyperconnectivity of local neocortical microcircuitry induced by prenatal exposure to valproic acid.

  Cerebral cortex (New York, N.Y. : 1991) 20080401

• Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects.

  Clinical pharmacology and therapeutics 20080401

• Valproate decreases EEG synchronization in a use-dependent manner in idiopathic generalized epilepsy.

  Seizure 20080401

• Divalproex, lithium and suicide among Medicaid patients with bipolar disorder.

  Journal of affective disorders 20080401

• Relationship of open acute mania treatment to blinded maintenance outcome in bipolar I disorder.

  Journal of affective disorders 20080401

• The Bipolar Comprehensive Outcomes Study (BCOS): baseline findings of an Australian cohort study.

  Journal of affective disorders 20080401

• Epilepsy in Angelman syndrome.

  Seizure 20080401

• Seizure-freedom with combination therapy in localization-related epilepsy.

  Seizure 20080401

• A simple and rapid determination of valproic acid in human plasma using a non-porous silica column and liquid chromatography with tandem mass spectrometric detection.

  Biomedical chromatography : BMC 20080401

• Anticonvulsants for the treatment of behavioral and psychological symptoms of dementia: a literature review.

  International psychogeriatrics 20080401

• Effects of divalproex on disruptive behavior of jail inmates.

  Progress in neuro-psychopharmacology & biological psychiatry 20080401

• Absence status epilepsy: delineation of a distinct idiopathic generalized epilepsy syndrome.

  Epilepsia 20080401

• The measurement of ammonia blood levels in patients taking valproic acid: looking for problems where they do not exist?

  Epilepsy & behavior : E&B 20080401

• Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.

  Progress in neuro-psychopharmacology & biological psychiatry 20080401

• Cinnarizine in refractory migraine prophylaxis: efficacy and tolerability. A comparison with sodium valproate.

  The journal of headache and pain 20080401

• Posterior reversible encephalopathy syndrome (PRES).

  International journal of obstetric anesthesia 20080401

• Clinical picture of EPM1-Unverricht-Lundborg disease.

  Epilepsia 20080401

• Treatment of newly diagnosed epilepsies: the shortcomings of SANAD.

  Developmental medicine and child neurology 20080401

• Valproate-induced pure red cell aplasia and megakaryocyte dysplasia.

  British journal of haematology 20080401

• Histone deacetylase inhibitors protect against and mitigate the lethality of total-body irradiation in mice.

  Radiation research 20080401

• ACOG Practice Bulletin: Clinical management guidelines for obstetrician-gynecologists number 92, April 2008 (replaces practice bulletin number 87, November 2007). Use of psychiatric medications during pregnancy and lactation.

  Obstetrics and gynecology 20080401

• Pharmacological treatment of pathologic aggression in children.

  International review of psychiatry (Abingdon, England) 20080401

• Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.

  Journal of inherited metabolic disease 20080401

• Sustained low-efficiency dialysis with filtration (SLEDD-f) in the management of acute sodium valproate intoxication.

  Hemodialysis international. International Symposium on Home Hemodialysis 20080401

• Prevention of hypoxia-induced neuronal apoptosis through histone deacetylase inhibition.

  The Journal of trauma 20080401

• Acute treatment of patients with bipolar mixed episodes.

  The Journal of clinical psychiatry 20080401

• A confusing case of confusion. Acute porphyrias.

  The Journal of the Oklahoma State Medical Association 20080401

• Evaluation of the mood-stabilizing agent valproic acid as a preventative for toxoplasmosis in mice and activity against tissue cysts in mice.

  The Journal of parasitology 20080401

• Loss of astrocytic domain organization in the epileptic brain.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080326

• New sulfurated derivatives of valproic acid with enhanced histone deacetylase inhibitory activity.

  Bioorganic & medicinal chemistry letters 20080315

• Synergistic neuroprotective effects of lithium and valproic acid or other histone deacetylase inhibitors in neurons: roles of glycogen synthase kinase-3 inhibition.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080305

• Nitromethane encephalopathy MRI.

  Neurology 20080304

• Translocation-positive acute myeloid leukemia associated with valproic acid therapy.

  Pediatric blood & cancer 20080301

• Abnormal fear conditioning and amygdala processing in an animal model of autism.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080301

• Phenytoin but not valproate directly affected in vitro trophoblast differentiation.

  European journal of obstetrics, gynecology, and reproductive biology 20080301

• Prenatal diagnosis of cerebral lesions in Tuberous sclerosis complex (TSC). Case report and review of the literature.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20080301

• Acute hemorrhagic pancreatitis due to the use of valproic acid in a child.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20080301

• Valproate (depakine-chrono) in the acute treatment of outpatients with generalized anxiety disorder without psychiatric comorbidity: randomized, double-blind placebo-controlled study.

  European psychiatry : the journal of the Association of European Psychiatrists 20080301

• Valproate-induced thrombocytopenia: a prospective monotherapy study.

  Epilepsia 20080301

• Glutathione-S-transferase (GST) M1 null genotype and combined GSTM1 and GSTT1 null genotypes are risk factors for increased serum gamma-glutamyltransferase in valproic acid-treated patients.

  Clinica chimica acta; international journal of clinical chemistry 20080301

• Intravenous valproate aborts glyceryl trinitrate-induced migraine attacks: a clinical and quantitative EEG study.

  Cephalalgia : an international journal of headache 20080301

• Trigonocephaly and valproate: a case report and review of literature.

  Prenatal diagnosis 20080301

• Histone deacetylase inhibitor treatment downregulates VLA-4 adhesion in hematopoietic stem cells and acute myeloid leukemia blast cells.

  Haematologica 20080301

• Use of intravenous valproic acid for acute migraine.

  The Annals of pharmacotherapy 20080301

• Antiepileptic drugs as human teratogens.

  Expert opinion on drug safety 20080301

• Increased left prefrontal activation during staring/mutism episodes in a patient with resistant catatonic schizophrenia: a near infrared spectroscopy study.

  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20080301

• Surviving blood loss without fluid resuscitation.

  The Journal of trauma 20080301

• [Valproate sodium is effective as prophylactic therapy for cyclic vomiting syndrome in a case].

  No to hattatsu = Brain and development 20080301

• Postictal transient hyperammonemia.

  The American journal of emergency medicine 20080301

• A case of hemoperfusion and L-carnitine management in valproic acid overdose.

  The American journal of emergency medicine 20080301

• Deconstructing a medication regimen.

  Journal of psychiatric practice 20080301

• [Secondary delirium due to the use of lamotrigine with abrupt increase valproic acid's dose].

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20080301

• Hallucinations during lamotrigine treatment.

  The Nurse practitioner 20080301

• [Visual auras in idiopathic generalized epilepsy].

  Revue neurologique 20080301

• Our work is still cut out for us..

  Epileptic disorders : international epilepsy journal with videotape 20080301

• [Mood stabilizers--past, present and future].

  Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20080301

• Lamotrigine and the risk of fulminant hepatic failure.

  Lancet (London, England) 20080223

• The oral absorption of phospholipid prodrugs: in vivo and in vitro mechanistic investigation of trafficking of a lecithin-valproic acid conjugate following oral administration.

  Journal of controlled release : official journal of the Controlled Release Society 20080218

• A successful outcome with valproic acid in a case of mania secondary to stroke of the right frontal lobe.

  Progress in neuro-psychopharmacology & biological psychiatry 20080215

• Comments on 'Addition of lamotrigine to valproic acid: a successful outcome in a case of rapid-cycling bipolar affective disorder'.

  Progress in neuro-psychopharmacology & biological psychiatry 20080215

• Effect of valproic acid on radiation-induced DNA damage in euchromatic and heterochromatic compartments.

  Cell cycle (Georgetown, Tex.) 20080215

• Chronic microinjection of valproic acid into the nucleus accumbens attenuates amphetamine-induced locomotor activity.

  Neuroscience letters 20080213

• Brain creatine kinase activity in an animal model of mania.

  Life sciences 20080213

• Valproic acid is a selective antiproliferative agent in estrogen-sensitive breast cancer cells.

  Cancer letters 20080208

• Swim stress exaggerates the hyperactive mesocortical dopamine system in a rodent model of autism.

  Brain research 20080208

• Chronic valproate normalizes behavior in mice overexpressing calcineurin.

  European journal of pharmacology 20080202

• [Metabolic encephalopathy can be a potentially life-threatening complication from valproic acid].

  Nederlands tijdschrift voor geneeskunde 20080202

• Mitochondrial DNA-dependent effects of valproate on mitochondrial calcium levels in transmitochondrial cybrids.

  The international journal of neuropsychopharmacology 20080201

• Adjunct extended-release valproate semisodium in late life schizophrenia.

  International journal of geriatric psychiatry 20080201

• Selective induction of apoptosis in leukemic B-lymphoid cells by a CD19-specific TRAIL fusion protein.

  Cancer immunology, immunotherapy : CII 20080201

• Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver.

  Toxicology and applied pharmacology 20080201

• Toxicity of valproic acid in mice with decreased plasma and tissue carnitine stores.

  The Journal of pharmacology and experimental therapeutics 20080201

• NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities.

  Blood 20080201

• Valproic acid interferes with antiviral treatment in human cytomegalovirus-infected endothelial cells.

  Cardiovascular research 20080201

• Botulinum toxin type A and divalproex sodium for prophylactic treatment of episodic or chronic migraine.

  Headache 20080201

• Inhibition of tumor-stromal interaction through HGF/Met signaling by valproic acid.

  Biochemical and biophysical research communications 20080201

• Inhibitors of histone deacetylase (HDAC) restore the p53 pathway in neuroblastoma cells.

  British journal of pharmacology 20080201

• Adiponectin and visfatin concentrations in children treated with valproic acid.

  Epilepsia 20080201

• Increased oxidative stress in epileptic children treated with valproic acid.

  Epilepsy research 20080201

• Valproate-induced change in hair color.

  Journal of the American Academy of Dermatology 20080201

• Oral valproic acid for epilepsy--long-term experience in therapy and side effects.

  Expert opinion on pharmacotherapy 20080201

• Divalproex in the treatment of posttraumatic stress disorder: a randomized, double-blind, placebo-controlled trial in a veteran population.

  Journal of clinical psychopharmacology 20080201

• Reversible valproate hepatotoxicity due to mutations in mitochondrial DNA polymerase gamma (POLG1).

  Archives of disease in childhood 20080201

• Characterization of non-linear relationship between total and unbound serum concentrations of valproic acid in epileptic children.

  Journal of clinical pharmacy and therapeutics 20080201

• More lessons for the treatment of chronic daily headache.

  The journal of headache and pain 20080201

• The effect of sodium valproate on chronic daily headache and its subgroups.

  The journal of headache and pain 20080201

• Potential relationships between transaminase abnormality and valproic acid clearance or serum carnitine concentrations in Japanese epileptic patients.

  The Journal of pharmacy and pharmacology 20080201

• Role of psychiatric medications as adjunct therapy in the treatment of HIV associated neurocognitive disorders.

  International review of psychiatry (Abingdon, England) 20080201

• Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera.

  Cancer science 20080201

• Augmentation of polysialic acid by valproic acid in early postnatal mouse hippocampus and primary cultured hippocampal neurons.

  Journal of bioscience and bioengineering 20080201

• Re: New lessons: classic treatments in convulsive status epilepticus.

  Irish medical journal 20080201

• Histone deacetylase inhibitors and hydroxyurea modulate the cell cycle and cooperatively induce apoptosis.

  Oncogene 20080131

• Possible new clinical sign of hyperammonemia.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20080129

• The role of hippocampal GluR1 and GluR2 receptors in manic-like behavior.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20080102

• A pilot study on the off-label use of valproic acid to treat adenomyosis.

  Fertility and sterility 20080101

• Synthesis and CNS depressant activity of some novel 3-[5-substituted 1,3,4-thiadiazole-2-yl]-2-styryl quinazoline-4(3H)-ones.

  European journal of medicinal chemistry 20080101

• Weight change in the acute treatment of bipolar I disorder: a naturalistic observational study of psychiatric inpatients.

  Journal of affective disorders 20080101

• Central nervous system involvement as a major manifestation of rheumatoid arthritis.

  Rheumatology international 20080101

• Acute hepatic injury in four children with Dravet syndrome: valproic acid, topiramate or acetaminophen?

  Seizure 20080101

• Hyponatremia associated with sodium valproate in a 22-year-old male.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080101

• [Malignant neuroleptic syndrome associated with amisulpride].

  Der Nervenarzt 20080101

• Pemoline (2-amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy.

  The Journal of pharmacology and experimental therapeutics 20080101

• Which patients become seizure free with antiepileptic drugs? An observational study in 821 patients with epilepsy.

  Acta neurologica Scandinavica 20080101

• Valproic acid sensitizes chronic lymphocytic leukemia cells to apoptosis and restores the balance between pro- and antiapoptotic proteins.

  Molecular medicine (Cambridge, Mass.) 20080101

• Can prolonged administration of valproic acid put patients with epilepsy at higher risk for development of Alzheimer's disease?

  Epilepsy & behavior : E&B 20080101

• An observational study of first-line valproate monotherapy in focal epilepsy.

  European journal of neurology 20080101

• The effect of anticonvulsant drugs on the fibrinolytic activity of tissue plasminogen activator.

  Cerebrovascular diseases (Basel, Switzerland) 20080101

• Childhood absence epilepsy with clinically apparent genetic and acquired burdens: a diagnostic consideration.

  Journal of child neurology 20080101

• Massive valproic acid overdose, a misleading case.

  The American journal of emergency medicine 20080101

• 'Armoured brain'. A case report of a calcified chronic subdural haematoma.

  Pediatric neurosurgery 20080101

• Ca2+/calmodulin-dependent protein kinase II--a target for sodium valproate?

  Neuroscience and behavioral physiology 20080101

• The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear.

  Learning & memory (Cold Spring Harbor, N.Y.) 20080101

• The treatment of the first seizure: the benefits.

  Epilepsia 20080101

• Severe acute hyperammonemia after brief exposure to valproate.

  Psychosomatics 20080101

• Valproic acid and CEBPalpha-mediated regulation of adipokine gene expression in hypothalamic neurons and 3T3-L1 adipocytes.

  Neuroendocrinology 20080101

• Conduct disorder in referred children and adolescents: clinical and therapeutic issues.

  Comprehensive psychiatry 20080101

• [Meropenem and valproic acid: a dangerous combination].

  Revista de neurologia 20080101

• [Coincidence of Graves' disease and Angelman syndrome in a 13 month old boy].

  Klinische Padiatrie 20080101

• [Management of comorbid bipolar disorder and alcohol dependence].

  Presse medicale (Paris, France : 1983) 20080101

• Valproate-induced subclinical hypothyroidism.

  The Journal of neuropsychiatry and clinical neurosciences 20080101

• Aripiprazole therapy in 20 older adults with bipolar disorder: a 12-week, open-label trial.

  The Journal of clinical psychiatry 20080101

• Pregnancy outcome after in utero exposure to valproate : evidence of dose relationship in teratogenic effect.

  CNS drugs 20080101

• Switching from other agents to extended-release carbamazepine in acute mania.

  Psychopharmacology bulletin 20080101

• Pharmacotherapy of mood disorders.

  Annual review of clinical psychology 20080101

• Growth inhibition and proapoptotic activity induction by IIF and valproic acid on RA-resistant leukemia cells.

  Anticancer research 20080101

• Valproate protective effects on cisplatin-induced peripheral neuropathy: an in vitro and in vivo study.

  Anticancer research 20080101

• Growing evidence to support early intervention in early onset bipolar disorder?

  The Australian and New Zealand journal of psychiatry 20080101

• Use of dronabinol for cannabis dependence: two case reports and review.

  The American journal on addictions 20080101

• Risperidone and valproate for mania following stroke.

  The Journal of neuropsychiatry and clinical neurosciences 20080101

• Hydroxamic acid and fluorinated derivatives of valproic acid: anticonvulsant activity, neurotoxicity and teratogenicity.

  Neurotoxicology and teratology 20080101

• Risk of hypospadias in newborn infants exposed to valproic acid during the first trimester of pregnancy: a case-control study in Spain.

  Drug safety 20080101

• Valproate treatment of acute alcohol hallucinosis: a double-blind, placebo-controlled study.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20080101

• Valproic acid sensitizes K562 erythroleukemia cells to TRAIL/Apo2L-induced apoptosis.

  Anticancer research 20080101

• Acute stroke-elicited epilepsia partialis continua responsive to intravenous sodium valproate.

  Neurologia i neurochirurgia polska 20080101

• Hemodiafiltration and high-flux hemodialysis significantly reduce serum valproate levels inducing epileptic seizures: case report.

  Blood purification 20080101

• Relationship between insight and neurocognition in patients with bipolar I disorder in remission.

  Comprehensive psychiatry 20080101

• Menstrual cycle dysfunction associated with neurologic and psychiatric disorders: their treatment in adolescents.

  Annals of the New York Academy of Sciences 20080101

• Prevention of bipolar disorder in at-risk children: theoretical assumptions and empirical foundations.

  Development and psychopathology 20080101

• Treatment of juvenile myoclonic epilepsy.

  CNS neuroscience & therapeutics 20080101

• Evaluation of the factors affecting the quality of life and total costs in epilepsy patients on monotherapy with carbamazepine and valproate.

  Folia medica 20080101

• Pharmacological treatment of alcohol hallucinosis.

  Alcohol and alcoholism (Oxford, Oxfordshire) 20080101

• Influence of valproic acid on outcome of high-grade gliomas in children.

  Anticancer research 20080101

• Role of Na+/L-carnitine transporter (OCTN2) in renal handling of pivaloylcarnitine and valproylcarnitine formed during pivalic acid-containing prodrugs and valproic acid treatment.

  Drug metabolism and pharmacokinetics 20080101

• Delayed thrombocytopenia after valproic acid overdose.

  General hospital psychiatry 20080101

• Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.

  Molecular cancer 20080101

• Valproate-induced hyperammonemic encephalopathy treated by hemodialysis.

  Renal failure 20080101

• [Impact of valproates on haemostasis and blood cell count in children].

  Srpski arhiv za celokupno lekarstvo 20080101

• Valproate-induced hyperammonemic encephalopathy without cognitive sequelae: a case report in the psychiatric setting.

  The Journal of neuropsychiatry and clinical neurosciences 20080101

• Reliability and validity of the Korean version of UKU-SERS-Pat in patients with bipolar disorder.

  Nordic journal of psychiatry 20080101

• [Diagnosis and treatment of epilepsy in the field of psychiatry].

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20080101

• Medication overuse headache: awareness, detection and treatment.

  CNS drugs 20080101

• Antileukemic activity of the combination of ionizing radiation with valproic acid in promyelocytic leukemia cells HL-60.

  Neoplasma 20080101

• 31P magnetic resonance spectroscopy of endothelial cells grown in three-dimensional matrigel construct as an enabling platform technology: I. The effect of glial cells and valproic acid on phosphometabolite levels.

  Endothelium : journal of endothelial cell research 20080101

• Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway.

  BMC cell biology 20080101

• Therapeutic drug monitoring of antiepileptic drugs.

  JNMA; journal of the Nepal Medical Association 20080101

• [Effect of GABA-positive drugs on the background and superior sagittalis sinus-electrostimulated activity of neurons in the nucleus trigeminalis caudalis of rats].

  Eksperimental'naia i klinicheskaia farmakologiia 20080101

• [Use of anticonvulsant pregabalin as an add-on therapy in patients with partial epilepsy with polymorphic seizures].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101

• Berardinelli-Seip syndrome in a 6-year-old boy.

  Indian journal of dermatology, venereology and leprology 20080101

• [Influence of the antagonist of adenosine A1 receptors, 8-cyclopentyl-1 ,3-dipropylxanthine, upon the anticonvulsant activity of antiepileptic drugs in mice].

  Przeglad lekarski 20080101

• [Endocrine effects of antiepileptic drugs].

  Przeglad lekarski 20080101

• [Do results of the recent clinical trials change the place of valproate in treatment of epilepsy?].

  Przeglad lekarski 20080101

• Antiapoptotic action of lithium and valproate.

  Pharmacological reports : PR 20080101

• Monotherapy versus combined treatment with second-generation antipsychotics in bipolar disorder.

  The Journal of clinical psychiatry 20080101

• Clinical decision making in the treatment of mania.

  The Journal of clinical psychiatry 20080101

• [Valproate-induced hyperammonemic encephalopathy. Review of cases in the psychiatric setting].

  Vertex (Buenos Aires, Argentina) 20080101

• Absence seizures in children.

  BMJ clinical evidence 20080101

• [Epigenetic regulation of expression of retinoic acid receptor beta gene in leukemia cell].

  Zhonghua yi xue za zhi 20071225

• Lamotrigine and the risk of fulminant hepatic failure.

  Lancet (London, England) 20071222

• Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.

  Journal of medicinal chemistry 20071213

• Imbalance between pro-inflammatory and anti-inflammatory cytokines in bipolar disorder.

  Journal of affective disorders 20071201

• Prophylactic treatment response in bipolar disorder: results of a naturalistic observation study.

  Journal of affective disorders 20071201

• The cognitive effects of oxcarbazepine versus carbamazepine or valproate in newly diagnosed children with partial seizures.

  Seizure 20071201

• Acute and chronic treatment with mianserin differentially affects the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.

  Psychopharmacology 20071201

• Valproic acid alters GnRH-GABA interactions in cycling female rats.

  Cellular and molecular neurobiology 20071201

• Myelodysplastic syndrome associated with chronic valproic acid therapy: a case report and review of the literature.

  Hematology (Amsterdam, Netherlands) 20071201

• Prescribing patterns of antiepileptic drugs in Italy: a nationwide population-based study in the years 2000-2005.

  European journal of neurology 20071201

• Functional characteristics and gene expression profiles of primary acute myeloid leukaemia cells identify patient subgroups that differ in susceptibility to histone deacetylase inhibitors.

  International journal of oncology 20071201

• The Australian Register of Antiepileptic Drugs in Pregnancy: the first 1002 pregnancies.

  The Australian & New Zealand journal of obstetrics & gynaecology 20071201

• Trichotillomania in acute Sydenham's chorea.

  The Australian and New Zealand journal of psychiatry 20071201

• Secondary bipolar disorder and Diogenes syndrome in frontotemporal dementia: behavioral improvement with quetiapine and sodium valproate.

  Journal of clinical psychopharmacology 20071201

• Divalproex sodium vs. valproic acid: drug utilization patterns, persistence rates and predictors of hospitalization among VA patients diagnosed with bipolar disorder.

  Journal of clinical pharmacy and therapeutics 20071201

• Clinical trials in spinal muscular atrophy.

  Current opinion in pediatrics 20071201

• Interaction between valproic acid and acyclovir after intravenous and oral administration in a rabbit model.

  Basic & clinical pharmacology & toxicology 20071201

• Aseptic meningitis associated with lamotrigine: report of two cases.

  European journal of neurology 20071201

• Valproic acid treatment in six patients with spinal muscular atrophy.

  European journal of neurology 20071201

• [A valproate-induced encephalopathy without hyperammonemia].

  Annales francaises d'anesthesie et de reanimation 20071201

• Identification of small molecules from human embryonic stem cells using metabolomics.

  Stem cells and development 20071201

• Thyroid function and volume in epileptic children using carbamazepine, oxcarbazepine and valproate.

  Pediatrics international : official journal of the Japan Pediatric Society 20071201

• Hyperammonemia and valproic acid-induced encephalopathy.

  The American journal of psychiatry 20071201

• Histone deacetylase inhibitor valproic acid inhibits proliferation and induces apoptosis in KM3 cells via downregulating VEGF receptor.

  Neuro endocrinology letters 20071201

• [Effects of sodium valproate on proliferation and apoptosis of human myelodysplastic syndromes cell line MUTZ-1].

  Ai zheng = Aizheng = Chinese journal of cancer 20071201

• Partial agenesis of the corpus callosum in a patient with juvenile myoclonic epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20071201

• Valproate and acetyl-L-carnitine prevent methamphetamine-induced behavioral sensitization in mice.

  Annals of the New York Academy of Sciences 20071201

• [Effects of mood stabilizer on the circadian system: possible implication for abnormalities in mood disorders].

  Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20071201

• Divalproex in the treatment of acute bipolar depression: a preliminary double-blind, randomized, placebo-controlled pilot study.

  The Journal of clinical psychiatry 20071201

• The role of ghrelin in weight gain and growth in epileptic children using valproate.

  Journal of child neurology 20071201

• Homocysteine levels in epileptic children receiving antiepileptic drugs.

  Journal of child neurology 20071201

• Pharmacokinetic modeling of valproate from clinical data in Serbian epileptic patients.

  Methods and findings in experimental and clinical pharmacology 20071201

• Family conflict moderates response to pharmacological intervention in pediatric bipolar disorder.

  Journal of child and adolescent psychopharmacology 20071201

• Juvenile myoclonic epilepsy.

  Arquivos de neuro-psiquiatria 20071201

• [Study of oro-dental injuries during seizures in Senegalese children with epilepsy].

  Odonto-stomatologie tropicale = Tropical dental journal 20071201

• Two cases of valproic acid poisoning treated with L-carnitine.

  Human & experimental toxicology 20071201

• Serum sodium valproate testing: is it appropriate?

  The Medical journal of Australia 20071119

• Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients.

  Blood 20071115

• Cholecalciferol enhances the anticonvulsant effect of conventional antiepileptic drugs in the mouse model of maximal electroshock.

  European journal of pharmacology 20071114

• Cingulate gyrus volumetry in drug free bipolar patients and patients treated with valproate or valproate and quetiapine.

  Journal of psychiatric research 20071101

• Inhibition of histone deacetylase enhances the anti-proliferative action of antiestrogens on breast cancer cells and blocks tamoxifen-induced proliferation of uterine cells.

  Breast cancer research and treatment 20071101

• Valproic acid induces p21 and topoisomerase-II (alpha/beta) expression and synergistically enhances etoposide cytotoxicity in human glioblastoma cell lines.

  Journal of neuro-oncology 20071101

• Bipolar pharmacotherapy and suicidal behavior Part 3: impact of antipsychotics.

  Journal of affective disorders 20071101

• Bipolar pharmacotherapy and suicidal behavior. Part I: Lithium, divalproex and carbamazepine.

  Journal of affective disorders 20071101

• Lack of pharmacokinetic interaction of levetiracetam on carbamazepine, valproic acid, topiramate, and lamotrigine in children with epilepsy.

  Epilepsia 20071101

• Searching for a needle in a haystack: use of ICD-9-CM codes in drug-induced liver injury.

  The American journal of gastroenterology 20071101

• The measurement of ammonia blood levels in patients taking valproic acid: looking for problems where they do not exist?

  Epilepsy & behavior : E&B 20071101

• Informing patients of the teratogenic potential of mood stabilizing drugs: a case note review of the practice of psychiatrists.

  Journal of psychopharmacology (Oxford, England) 20071101

• Valproate-induced developmental neurotoxicity is affected by maternal conditions including shipping stress and environmental change during early pregnancy.

  Toxicology letters 20071101

• Valproate-induced hyperammonaemic encephalopathy: review of 14 cases in the psychiatric setting.

  International clinical psychopharmacology 20071101

• Risperidone alone versus risperidone plus valproate in the treatment of patients with schizophrenia and hostility.

  International clinical psychopharmacology 20071101

• Interaction of Delta sleep-inducing peptide and valproate on metaphit audiogenic seizure model in rats.

  Cellular and molecular neurobiology 20071101

• Antipsychotic medication dispensing and risk of death in veterans and war widows 65 years and older.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20071101

• Lamotrigine serum concentrations under valproate comedication: 'contraindication' or 'safe combination'? A case report.

  Pharmacopsychiatry 20071101

• [Analysis of hypofibrinogenemias found on routine coagulation screening tests and identification of heterozygous dysfibrinogenemia or fibrinogen deficiency].

  Rinsho byori. The Japanese journal of clinical pathology 20071101

• [Valproate-associated hyperammonemic encephalopathy. Report of one case].

  Revista medica de Chile 20071101

• [Epigenetic model in the pharmacologic modulation of vulnerability to schizophrenia].

  L'Encephale 20071101

• Fructose-1,6-bisphosphate has anticonvulsant activity in models of acute seizures in adult rats.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20071031

• [Drug-induced pancreatitis].

  Nihon rinsho. Japanese journal of clinical medicine 20071028

• Valproic acid sodium inhibits the morphine-induced conditioned place preference in the central nervous system of rats.

  Neuroscience letters 20071022

• Lamotrigine extended-release as adjunctive therapy for partial seizures.

  Neurology 20071016

• Valproic acid and other histone deacetylase inhibitors induce microglial apoptosis and attenuate lipopolysaccharide-induced dopaminergic neurotoxicity.

  Neuroscience 20071012

• Unlike lithium, anticonvulsants and antidepressants do not alter rat brain myo-inositol.

  Neuroreport 20071008

• Downregulation of c-Myc is critical for valproic acid-induced growth arrest and myeloid differentiation of acute myeloid leukemia.

  Leukemia research 20071001

• Reversible effects of antiepileptic drugs on reproductive endocrine function in men and women with epilepsy--a prospective randomized double-blind withdrawal study.

  Epilepsia 20071001

• Motor correlates of models of secondary bilateral synchrony and multiple epileptic foci.

  Seizure 20071001

• Divalproex sodium for the treatment of PTSD and conduct disordered youth: a pilot randomized controlled clinical trial.

  Child psychiatry and human development 20071001

• Neocortical gray matter volume in first-episode schizophrenia and first-episode affective psychosis: a cross-sectional and longitudinal MRI study.

  Biological psychiatry 20071001

• Up-regulation of cPLA(2) gene expression in astrocytes by all three conventional anti-bipolar drugs is drug-specific and enzyme-specific.

  Psychopharmacology 20071001

• Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome.

  Blood 20071001

• Glycopyrrolate for clozapine-induced sialorrhea.

  Progress in neuro-psychopharmacology & biological psychiatry 20071001

• Addition of lamotrigine to valproic acid: a successful outcome in a case of rapid-cycling bipolar affective disorder.

  Progress in neuro-psychopharmacology & biological psychiatry 20071001

• Levetiracetam, phenytoin, and valproate act differently on rat bone mass, structure, and metabolism.

  Epilepsia 20071001

• Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death.

  Journal of neurochemistry 20071001

• Cytoskeleton of hippocampal neurons as a target for valproic acid in an experimental model of depression.

  Progress in neuro-psychopharmacology & biological psychiatry 20071001

• Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response.

  Experimental hematology 20071001

• Anticonvulsant, but not antiepileptic, action of valproate on audiogenic seizures in metaphit-treated rats.

  Clinical and experimental pharmacology & physiology 20071001

• Conversion to lamotrigine monotherapy from valproate monotherapy in older adolescent patients with epilepsy.

  Current medical research and opinion 20071001

• Open-label steady-state pharmacokinetic drug interaction study on co-administered quetiapine fumarate and divalproex sodium in patients with schizophrenia, schizoaffective disorder, or bipolar disorder.

  Human psychopharmacology 20071001

• Resolution of haloperidol-induced hyperprolactinemia with aripiprazole.

  Journal of clinical psychopharmacology 20071001

• Intravenous valproate treatment of uncontrollable aggression: a case report.

  Journal of clinical psychopharmacology 20071001

• Subcutaneous histamine versus sodium valproate in migraine prophylaxis: a randomized, controlled, double-blind study.

  European journal of neurology 20071001

• Population pharmacokinetics of valproate in Chinese children with epilepsy.

  Acta pharmacologica Sinica 20071001

• Increased plasma leptin levels and valproate use in patients with Rett syndrome.

  The Journal of pediatrics 20071001

• Population pharmacokinetics of valproic acid concentrations in elderly nursing home residents.

  Therapeutic drug monitoring 20071001

• A randomised controlled trial examining the longer-term outcomes of standard versus new antiepileptic drugs. The SANAD trial.

  Health technology assessment (Winchester, England) 20071001

• A systematic review and economic model of the clinical effectiveness and cost-effectiveness of interventions for preventing relapse in people with bipolar disorder.

  Health technology assessment (Winchester, England) 20071001

• The relevance of estrogen receptor-beta expression to the antiproliferative effects observed with histone deacetylase inhibitors and phytoestrogens in prostate cancer treatment.

  Molecular cancer therapeutics 20071001

• Intravenous sodium valproate versus diazepam infusion for the control of refractory status epilepticus in children: a randomized controlled trial.

  Journal of child neurology 20071001

• Novel endocrine disrupter effects of classic and atypical antipsychotic agents and divalproex: induction of adrenal hyperandrogenism, reversible with metformin or rosiglitazone.

  Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20071001

• A pharmacokinetic and clinical evaluation of switching patients with bipolar I disorder from delayed-release to extended-release divalproex.

  The Journal of clinical psychiatry 20071001

• Sodium valproate does not augment Prpsc in murine neuroblastoma cells.

  Neurotoxicity research 20071001

• Age and gender effects on olanzapine and risperidone plasma concentrations in children and adolescents.

  Journal of child and adolescent psychopharmacology 20071001

• Imipramine, methylphenidate and valproic acid-related EPS in a child: a case report.

  The international journal of neuropsychopharmacology 20071001

• An evaluation of a novel chick cardiomyocyte micromass culture assay with two teratogens/embryotoxins associated with heart defects.

  Alternatives to laboratory animals : ATLA 20071001

• Treatment of infantile spasms with sodium valproate followed by benzodiazepines.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20071001

• [Determination of valproic acid by on-line coupled capillary isotachophoresis with capillary zone electrophoresis with conductometric detection].

  Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20071001

• [Seven cases of decreased serum valproic acid concentration during concomitant use of carbapenem antibiotics].

  The Korean journal of laboratory medicine 20071001

• Congenital gingival hyperplasia in a neonate with foetal valproate syndrome.

  Neuropediatrics 20071001

• Reduction of dominant or submissive behaviors as models for antimanic or antidepressant drug testing: technical considerations.

  Journal of neuroscience methods 20070930

• Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915

• A case of valproate-induced hyperammonemic encephalopathy: look beyond the liver.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070911

• Therapeutic drug and cardiovascular disease risk monitoring in patients with bipolar disorder.

  Journal of affective disorders 20070901

• A peculiar form of epilepsy induced by crying in infancy.

  Brain & development 20070901

• Proteomic analysis of MOLT-4 cells treated by valproic acid.

  Molecular and cellular biochemistry 20070901

• Lithium and valproate protect hippocampal slices against ATP-induced cell death.

  Neurochemical research 20070901

• Reversible hepatotoxicity, pancreatitis, coagulation disorder and simultaneous bone marrow suppression with valproate in a 2-year-old girl.

  Seizure 20070901

• Prenatal exposure to valproic acid disturbs the enkephalinergic system functioning, basal hedonic tone, and emotional responses in an animal model of autism.

  Psychopharmacology 20070901

• Randomized study of intravenous valproate and phenytoin in status epilepticus.

  Seizure 20070901

• Influence of chronic hepatic failure on disposition kinetics of valproate excretion through a phase II reaction in rats treated with carbon tetrachloride.

  Biopharmaceutics & drug disposition 20070901

• Valproic acid for the treatment of myeloid malignancies.

  Cancer 20070901

• The histone deacetylase inhibitors suberoylanilide hydroxamic (Vorinostat) and valproic acid induce irreversible and MDR1-independent resistance in human colon cancer cells.

  International journal of oncology 20070901

• Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901

• Risk of death associated with antipsychotic drug dispensing in residential aged care facilities.

  The Australian and New Zealand journal of psychiatry 20070901

• Early intervention for the ocular and neurodevelopmental sequelae of Fetal Valproate Syndrome.

  Journal of paediatrics and child health 20070901

• [Meningovascular neurosyphilis].

  Revista clinica espanola 20070901

• [Behçet's disease in treatment with cyclosporine and seizures: diagnostic dilemma].

  Revista clinica espanola 20070901

• Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation.

  Biochimica et biophysica acta 20070901

• Chronic valproic acid intoxication: reversal by naloxone.

  Emergency medicine journal : EMJ 20070901

• Chronic administration of valproic acid inhibits PC3 cell growth by suppressing tumor angiogenesis in vivo.

  International journal of urology : official journal of the Japanese Urological Association 20070901

• A phase II study of epigenetic therapy with hydralazine and magnesium valproate to overcome chemotherapy resistance in refractory solid tumors.

  Annals of oncology : official journal of the European Society for Medical Oncology 20070901

• A case of Pallister-Killian syndrome associated with West syndrome.

  Pediatric neurology 20070901

• Short-term efficacy and safety of valproate sustained-release formulation in newly diagnosed partial epilepsy VIPe-study. A multicenter observational open-label study.

  Saudi medical journal 20070901

• Agomelatine adjunctive therapy for acute bipolar depression: preliminary open data.

  Bipolar disorders 20070901

• [Effect of valproate acid sodium on apoptosis of human gastric cancer cells and its mechanism study].

  Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20070901

• Irinotecan chemotherapy during valproic acid treatment: pharmacokinetic interaction and hepatotoxicity.

  Cancer biology & therapy 20070901

• Augmentation of clozapine with valproic Acid for clozapine-induced obsessive-compulsive symptoms.

  Pharmacopsychiatry 20070901

• [Evaluation of bone mineral density using digital image processing in children receiving anticonvulsants].

  No to hattatsu = Brain and development 20070901

• Paroxysmal tonic upgaze of childhood with co-existent absence epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20070901

• Juvenile myoclonic epilepsy starting in the eighth decade.

  Epileptic disorders : international epilepsy journal with videotape 20070901

• Menopause manifesting as bipolar symptoms.

  Journal of psychiatric practice 20070901

• Valproic acid enhances tubulin acetylation and apoptotic activity of paclitaxel on anaplastic thyroid cancer cell lines.

  Endocrine-related cancer 20070901

• Treatment of infantile spasms with sodium valproate followed by benzodiazepines.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070901

• Report on an open-label prospective study of divalproex sodium for the behavioral and psychological symptoms of dementia as monotherapy and in combination with second-generation antipsychotic medication.

  The American journal of geriatric pharmacotherapy 20070901

• Effect of Ginkgo biloba extract on oxidative metabolism of valproic acid in hepatic microsomes from donors with the CYP2C9*1/*1 genotype.

  Canadian journal of physiology and pharmacology 20070901

• Case files of the Children's Hospital of Michigan Regional Poison Control Center: the use of carnitine for the management of acute valproic acid toxicity.

  Journal of medical toxicology : official journal of the American College of Medical Toxicology 20070901

• Defective cholesterol traffic and neuronal differentiation in neural stem cells of Niemann-Pick type C disease improved by valproic acid, a histone deacetylase inhibitor.

  Biochemical and biophysical research communications 20070831

• Valproate induces apoptosis by inducing accumulation of neutral lipids which was prevented by disruption of the SIR2 gene in Saccharomyces cerevisiae.

  FEBS letters 20070821

• Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibition.

  Bioorganic & medicinal chemistry letters 20070815

• [Studies on the target cells and molecules with sodium valproate induced differential of human glioma cells].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20070815

• Elevated NMDA receptor levels and enhanced postsynaptic long-term potentiation induced by prenatal exposure to valproic acid.

  Proceedings of the National Academy of Sciences of the United States of America 20070814

• Crystal structure and anticonvulsant activity of (+/-)-1,2:4,5-di-O-isopropylidene-3,6-di-O-(2-propylpentanoyl)-myo-inositol.

  Carbohydrate research 20070813

• [Neuromuscular disorders caused by adverse effects of antiepileptics].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070810

• [Effect of UGT1A6 genetic polymorphisms on the metabolism of sodium valproate].

  Zhonghua yi xue za zhi 20070807

• Inhibition of histone deacetylase on ventricular remodeling in infarcted rats.

  American journal of physiology. Heart and circulatory physiology 20070801

• Kinetics of valproic acid glucuronidation: evidence for in vivo autoactivation.

  Drug metabolism and disposition: the biological fate of chemicals 20070801

• The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees?

  Cellular and molecular life sciences : CMLS 20070801

• Beneficial effects of antiepileptic medication on absence seizures and cognitive functioning in children.

  Epilepsy & behavior : E&B 20070801

• Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock.

  Epilepsy & behavior : E&B 20070801

• Cervical dystonia due to interaction of valproic acid and quetiapine.

  Journal of clinical psychopharmacology 20070801

• Treatment adherence in individuals with rapid cycling bipolar disorder: results from a clinical-trial setting.

  Journal of clinical psychopharmacology 20070801

• Valproate protein binding following rapid intravenous administration of high doses of valproic acid in patients with epilepsy.

  Journal of clinical pharmacy and therapeutics 20070801

• Cost analysis of divalproex sodium extended-release compared to valproic acid in the treatment of bipolar disorder.

  Current medical research and opinion 20070801

• Risk factors for development of subclinical hypothyroidism during valproic acid therapy.

  The Journal of pediatrics 20070801

• Valproic acid combined with 13-cis retinoic acid and 1,25-dihydroxyvitamin D3 in the treatment of patients with myelodysplastic syndromes.

  Haematologica 20070801

• Acute seizures in a patient receiving divalproex sodium after starting ertapenem therapy.

  Pharmacotherapy 20070801

• Furosemide potentiates the anticonvulsant action of valproate in the mouse maximal electroshock seizure model.

  Epilepsy research 20070801

• Non-convulsive status epilepticus secondary to valproic acid-induced hyperammonemic encephalopathy.

  Acta neurologica Scandinavica 20070801

• Visual field defect during therapy with valproic-acid.

  European journal of neurology 20070801

• Facial emotion processing in acutely ill and euthymic patients with pediatric bipolar disorder.

  Journal of the American Academy of Child and Adolescent Psychiatry 20070801

• Effect of open-label lamotrigine as monotherapy and adjunctive therapy on the self-assessed cognitive function scores of patients with bipolar I disorder.

  Journal of clinical psychopharmacology 20070801

• Chronic treatment of rats with sodium valproate downregulates frontal cortex NF-kappaB DNA binding activity and COX-2 mRNA.

  Bipolar disorders 20070801

• GABAergic drugs for the treatment of migraine.

  CNS & neurological disorders drug targets 20070801

• Pharmacotherapeutic strategies for pediatric bipolar disorder.

  Expert opinion on pharmacotherapy 20070801

• [Apoptosis of human myelodysplastic syndrome cell Line MUTZ-1 induced by sodium valproate].

  Zhongguo shi yan xue ye xue za zhi 20070801

• Multiple system atrophy due to prolonged valproic acid treatment.

  International psychogeriatrics 20070801

• Valproic acid activates notch-1 signaling and regulates the neuroendocrine phenotype in carcinoid cancer cells.

  The oncologist 20070801

• Old versus new antiepileptic drugs: the SANAD study.

  Lancet (London, England) 20070728

• Old versus new antiepileptic drugs: the SANAD study.

  Lancet (London, England) 20070728

• Histone deacetylase inhibitors modulates the induction and expression of amphetamine-induced behavioral sensitization partially through an associated learning of the environment in mice.

  Behavioural brain research 20070719

• Valproic acid (VPA) in patients with refractory advanced cancer: a dose escalating phase I clinical trial.

  British journal of cancer 20070716

• Thalidomide inhibits pentylenetetrazole-induced seizures.

  Journal of the neurological sciences 20070715

• Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.

  European journal of pharmacology 20070712

• Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis.

  European journal of pharmacology 20070712

• Health-related quality of life and its predictive role for analgesic effect in patients with painful polyneuropathy.

  European journal of pain (London, England) 20070701

• An interaction study between the new antiepileptic and CNS drug carisbamate (RWJ-333369) and lamotrigine and valproic acid.

  Epilepsia 20070701

• Idiosyncratic adverse reactions to antiepileptic drugs.

  Epilepsia 20070701

• Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.

  Drug metabolism and disposition: the biological fate of chemicals 20070701

• Sodium valproate, hyperandrogenism and altered ovarian function in Indian women with epilepsy: a prospective study.

  Epilepsia 20070701

• Membrane expression of DR4, DR5 and caspase-8 levels, but not Mcl-1, determine sensitivity of human myeloma cells to Apo2L/TRAIL.

  Experimental cell research 20070701

• Multiple Molecular pathways explain the anti-proliferative effect of valproic acid on prostate cancer cells in vitro and in vivo.

  The Prostate 20070701

• Lamotrigine in children and adolescents: the impact of age on its serum concentrations and on the extent of drug interactions.

  European journal of clinical pharmacology 20070701

• Lamotrigine is neuroprotective in the energy deficiency model of MPTP intoxicated mice.

  Pediatric research 20070701

• A double blind, randomized, placebo-controlled trial of quetiapine as an add-on therapy to lithium or divalproex for the treatment of bipolar mania.

  International clinical psychopharmacology 20070701

• The measurement and magnitude of awareness difficulties after traumatic brain injury: a longitudinal study.

  Journal of the International Neuropsychological Society : JINS 20070701

• Sodium valproate versus lamotrigine: a randomised comparison of efficacy, tolerability and effects on circulating androgenic hormones in newly diagnosed epilepsy.

  Epilepsy research 20070701

• Metabolic and hormonal disturbances in women with epilepsy on antiepileptic drug monotherapy.

  Epilepsia 20070701

• Adherence to pharmacological treatment for juvenile bipolar disorder.

  Journal of the American Academy of Child and Adolescent Psychiatry 20070701

• Hyperammonemia due to valproic acid in the psychiatric setting.

  The American journal of psychiatry 20070701

• Histone deacetylase inhibitors affect dendritic cell differentiation and immunogenicity.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20070701

• Interaction between valproate and meropenem: a retrospective study.

  The Annals of pharmacotherapy 20070701

• Levetiracetam attenuates spontaneous spike-and-wave discharges in DBA/2J mice.

  Epilepsy research 20070701

• Valproate selectively reduces EEG activity in anterior parts of the cortex in patients with idiopathic generalized epilepsy. A low resolution electromagnetic tomography (LORETA) study.

  Epilepsy research 20070701

• Diagnosis of nonketotic hyperglycinemia in patients treated with valproic acid.

  Pediatric neurology 20070701

• Valproic acid-induced pancreatitis.

  Journal of gastroenterology 20070701

• Dosing of divalproex extended release.

  The Journal of clinical psychiatry 20070701

• Diagnosis of Parkinsonism in older patients receiving sodium valproate.

  Movement disorders : official journal of the Movement Disorder Society 20070615

• An ImmunoChip prototype for simultaneous detection of antiepileptic drugs using an enhanced one-step homogeneous immunoassay.

  Analytical biochemistry 20070615

• Anti-glutamatergic effect of riluzole: comparison with valproic acid.

  Neuroscience 20070615

• Coexistence of epileptic nocturnal wanderings and an arachnoid cyst.

  Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20070615

• Valproic acid inhibits adhesion of vincristine- and cisplatin-resistant neuroblastoma tumour cells to endothelium.

  British journal of cancer 20070604

• Modification of spatial recognition memory and object discrimination after chronic administration of haloperidol, amitriptyline, sodium valproate or olanzapine in normal and anhedonic rats.

  The international journal of neuropsychopharmacology 20070601

• Superior oblique myokymia: efficacy of medical treatment.

  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20070601

• Valproic acid induces neuroendocrine differentiation and UGT2B7 up-regulation in human prostate carcinoma cell line.

  Drug metabolism and disposition: the biological fate of chemicals 20070601

• Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action.

  The Journal of pharmacology and experimental therapeutics 20070601

• Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.

  The Journal of pharmacology and experimental therapeutics 20070601

• Antiepileptic drugs prevent changes induced by pilocarpine model of epilepsy in brain ecto-nucleotidases.

  Neurochemical research 20070601

• Different clinical manifestations of hyperammonemic encephalopathy.

  Epilepsy & behavior : E&B 20070601

• Attenuation of phospholipid signaling provides a novel mechanism for the action of valproic acid.

  Eukaryotic cell 20070601

• Juvenile myoclonic epilepsy: a benign disorder? Personality traits and psychiatric symptoms.

  Epilepsy & behavior : E&B 20070601

• Different serum concentrations of steady-state valproic acid in two sustained-release formulations.

  Psychiatry and clinical neurosciences 20070601

• Sexual disinhibition in schizophrenia possibly induced by risperidone and quetiapine.

  Psychiatry and clinical neurosciences 20070601

• Topiramate or valproate in patients with juvenile myoclonic epilepsy: a randomized open-label comparison.

  Epilepsy & behavior : E&B 20070601

• Leptin and insulin homeostasis in epilepsy: relation to weight adverse conditions.

  Epilepsy research 20070601

• Inhibitory effect of valproic acid on cytochrome P450 2C9 activity in epilepsy patients.

  Basic & clinical pharmacology & toxicology 20070601

• Update of the medical treatment of West syndrome.

  Minerva pediatrica 20070601

• Video-EEG in syncopal attack due to ocular compression in an adolescent mistreated for epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20070601

• Impaired verbal memory and otherwise spared cognition in remitted bipolar patients on monotherapy with lithium or valproate.

  Bipolar disorders 20070601

• Antiepileptic drugs and the significance of event-related potentials.

  Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 20070601

• An open-label trial of divalproex extended-release in the treatment of borderline personality disorder.

  CNS spectrums 20070601

• New statistical method for analyzing time to first seizure: example using data comparing carbamazepine and valproate monotherapy.

  Epilepsia 20070601

• Valproate in the treatment of PTSD: systematic review and meta analysis.

  Current medical research and opinion 20070601

• The effect of adjunctive mood stabilizers on antipsychotic utilization pattern and health resource utilization for Medicaid enrollees with schizophrenia.

  Current medical research and opinion 20070601

• Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver.

  Surgery 20070601

• Valproic acid monotherapy leads to CR in a patient with refractory diffuse large B cell lymphoma.

  Leukemia & lymphoma 20070601

• Effects of sodium valproate and carbamazepine on food competition aggression in pigeons.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070601

• [Effects of topiramate and valproate acid on serum insulin and leptin levels in young and adult rats].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20070601

• Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro.

  The Journal of parasitology 20070601

• Psychopharmacology news. New side effects of agents.

  Journal of child and adolescent psychopharmacology 20070601

• Molecular targets and early response biomarkers for the prediction of developmental toxicity in vitro.

  Alternatives to laboratory animals : ATLA 20070601

• [Assessment of depakine treatment of patients with endogen psychosis (clinical trial)].

  Georgian medical news 20070601

• [Cessation of epileptic seizures series using peroral valproate in an adult patient with partial epilepsy].

  Vojnosanitetski pregled 20070601

• Collapsing focal segmental glomerulosclerosis as a possible complication of valproic acid.

  South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20070601

• Hyperactivity and inattention--a successful response to table coffee.

  Nigerian journal of clinical practice 20070601

• Epigenetic modulation of seizure-induced neurogenesis and cognitive decline.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070530

• Sodium valproate exerts neuroprotective effects in vivo through CREB-binding protein-dependent mechanisms but does not improve survival in an amyotrophic lateral sclerosis mouse model.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20070523

• [Bipolar disorders: the disease of extreme emotions].

  MMW Fortschritte der Medizin 20070521

• Addition of histone deacetylase inhibitors in combination therapy.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070520

• Phase I trial of histone deacetylase inhibition by valproic acid followed by the topoisomerase II inhibitor epirubicin in advanced solid tumors: a clinical and translational study.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070520

• Gadd45a, the gene induced by the mood stabilizer valproic acid, regulates neurite outgrowth through JNK and the substrate paxillin in N1E-115 neuroblastoma cells.

  Experimental cell research 20070515

• Quetiapine for acute mania in bipolar disorder.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070515

• Estimation of the embryotoxic effect of CBZ using an ES cell differentiation system.

  Biochemical and biophysical research communications 20070511

• Effects of lithium and valproate on hippocampus citrate synthase activity in an animal model of mania.

  Progress in neuro-psychopharmacology & biological psychiatry 20070509

• Quantification of valproic acid and its metabolite 2-propyl-4-pentenoic acid in human plasma using HPLC-MS/MS.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

• Determination of valproic acid in human serum and pharmaceutical preparations by headspace liquid-phase microextraction gas chromatography-flame ionization detection without prior derivatization.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

• Modulation of angiogenesis by dithiolethione-modified NSAIDs and valproic acid.

  British journal of pharmacology 20070501

• Is valproate encephalopathy under-recognised in older people? A case series.

  Age and ageing 20070501

• Valproic acid-mediated neuroprotection in intracerebral hemorrhage via histone deacetylase inhibition and transcriptional activation.

  Neurobiology of disease 20070501

• Anticonvulsant efficacy of valproate-like carboxylic acids: a potential target for anti-bipolar therapy.

  Bipolar disorders 20070501

• Specificity of mood stabilizer action on neuronal growth cones.

  Bipolar disorders 20070501

• Effects of mood stabilizers on the inhibition of adenylate cyclase via dopamine D(2)-like receptors.

  Bipolar disorders 20070501

• Nonconvulsive status epilepticus in a neurological intensive care unit: profile in a developing country.

  Epilepsia 20070501

• The effect of sodium valproate on proton MRS visible neurochemical concentrations.

  Epilepsy research 20070501

• Response and remission in adolescent mania: signal detection analyses of the young mania rating scale.

  Journal of the American Academy of Child and Adolescent Psychiatry 20070501

• Comparison of two anticonvulsants in a randomized, single-blind treatment of hypomanic symptoms in patients with bipolar disorder.

  The Australian and New Zealand journal of psychiatry 20070501

• Double-blind, placebo-controlled trial of divalproex monotherapy in the treatment of symptomatic youth at high risk for developing bipolar disorder.

  The Journal of clinical psychiatry 20070501

• Valproic acid-induced eosinophilic pleural effusion: a case report and review of the literature.

  The American journal of the medical sciences 20070501

• Antiepileptic drugs in the prophylaxis of migraine, chronic headache forms and cluster headache: a review of their efficacy and tolerability.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20070501

• [A severe disabled case of incomplete Fanconi syndrome after discontinuation of carnitine supplementation during valproate sodium therapy].

  No to hattatsu = Brain and development 20070501

• [Clinical observation of valproate sodium-induced nocturnal enuresis].

  No to hattatsu = Brain and development 20070501

• Hemifacial seizures and cerebellar tumor: a rare co-existence.

  Indian pediatrics 20070501

• Effects of comedication on the serum levels of aripiprazole: evidence from a routine therapeutic drug monitoring service.

  Pharmacopsychiatry 20070501

• A closer look: the benefits and effectiveness of cognitive behavioral therapy on a female-specific unit for treatment of bipolar disorder.

  Issues in mental health nursing 20070501

• Fatal valproate overdose in a newborn baby.

  Human & experimental toxicology 20070501

• Current treatment of West syndrome in Japan.

  Journal of child neurology 20070501

• [[Severe phenytoin intoxication in patients with hypoalbuminaemia].

  Nederlands tijdschrift voor geneeskunde 20070428

• [Comorbidities in migraine patients].

  MMW Fortschritte der Medizin 20070419

• Inhibitors of histone deacetylases as potential therapeutic tools for high-risk embryonal tumors of the nervous system of childhood.

  International journal of cancer 20070415

• Boric acid inhibits embryonic histone deacetylases: a suggested mechanism to explain boric acid-related teratogenicity.

  Toxicology and applied pharmacology 20070415

• Sodium valproate at therapeutic concentrations changes Ca2+ response accompanied with its weak inhibition of protein kinase C in human astrocytoma cells.

  Progress in neuro-psychopharmacology & biological psychiatry 20070413

• Effects of acute and chronic valproate treatments on p-CREB levels in the rat amygdala and nucleus accumbens.

  Brain research 20070413

• Fatal reactivation of hepatitis B with temozolomide.

  The New England journal of medicine 20070412

• [Nocturnal epilepsy associated with sleep apnea syndrome].

  Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20070410

• Histone deacetylase inhibitors suppress natural killer cell cytolytic activity.

  FEBS letters 20070403

• Effect of valproic acid on withdrawal therapy in patients with overuse of chronic daily headache medications.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20070401

• The efficacy of sodium valproate and a MRA finding in confusional migraine.

  Brain & development 20070401

• Idiopathic hypereosinophilic syndrome complicated by central sinovenous thrombosis.

  Brain & development 20070401

• Valproate or olanzapine add-on to lithium: an 8-week, randomized, open-label study in Italian patients with a manic relapse.

  Journal of affective disorders 20070401

• Treatment of interictal epileptiform discharges in cerebral palsy patients without clinical epilepsy: hope for a better outcome in prognosis.

  Clinical neurology and neurosurgery 20070401

• Valproate, weight gain and carbohydrate craving: a gender study.

  Seizure 20070401

• Effects of valproic acid on hearing in epileptic patients.

  International journal of pediatric otorhinolaryngology 20070401

• Prospective assessment of levetiracetam pharmacokinetics during dose escalation in 4- to 12-year-old children with partial-onset seizures on concomitant carbamazepine or valproate.

  Epilepsy research 20070401

• Valproic acid affects membrane trafficking and cell-wall integrity in fission yeast.

  Genetics 20070401

• Gene expression profiles of murine fatty liver induced by the administration of valproic acid.

  Toxicology and applied pharmacology 20070401

• Studies on the extra-mitochondrial CoA -ester formation of valproic and Delta4 -valproic acids.

  Biochimica et biophysica acta 20070401

• Antiepileptic drugs in migraine: from clinical aspects to cellular mechanisms.

  Trends in pharmacological sciences 20070401

• Teratogenesis of sodium valproate.

  Current opinion in neurology 20070401

• Apium graveolens modulates sodium valproate-induced reproductive toxicity in rats.

  Journal of experimental zoology. Part A, Ecological genetics and physiology 20070401

• Clinical utility of a continuous intravenous infusion of valproic acid in pediatric patients.

  Pharmacotherapy 20070401

• Adverse events caused by drug interactions involving glucuronoconjugates of zidovudine, valproic acid and lamotrigine, and analysis of how such potential events are discussed in package inserts of Japan, UK and USA.

  Journal of clinical pharmacy and therapeutics 20070401

• Reversible cognitive and neurological symptoms during valproic acid therapy.

  Journal of the American Geriatrics Society 20070401

• Motor cortex excitability after vagus nerve stimulation in major depression.

  Journal of clinical psychopharmacology 20070401

• Cognitive side effects of valproic acid-induced hyperammonemia in children with epilepsy.

  Journal of clinical psychopharmacology 20070401

• [Clinical standing of valproate treatment of bipolar disorders].

  Fortschritte der Neurologie-Psychiatrie 20070401

• Fetal exposure to GABA-acting antiepileptic drugs generates hippocampal and cortical dysplasias.

  Epilepsia 20070401

• Valproate robustly increases Sp transcription factor-mediated expression of the dopamine transporter gene within dopamine cells.

  The European journal of neuroscience 20070401

• Effect of histone deacetylase inhibitor valproic acid on progenitor cells of acute myeloid leukemia.

  Haematologica 20070401

• Carnitine as an antidote for acute valproate toxicity in children.

  Current opinion in pediatrics 20070401

• Antiepileptic drugs and mood stability.

  Clinical EEG and neuroscience 20070401

• Histone modifications around individual BDNF gene promoters in prefrontal cortex are associated with extinction of conditioned fear.

  Learning & memory (Cold Spring Harbor, N.Y.) 20070401

• Human melatonin MT1 receptor induction by valproic acid and its effects in combination with melatonin on MCF-7 breast cancer cell proliferation.

  European journal of pharmacology 20070329

• The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial.

  Lancet (London, England) 20070324

• Regional cerebral glucose metabolic abnormalities in bipolar II depression.

  Biological psychiatry 20070315

• New device to control combined lingual and palatal myoclonus.

  Movement disorders : official journal of the Movement Disorder Society 20070315

• No cure yet for HIV-1, but therapeutic research presses on.

  The Journal of infectious diseases 20070315

• Stability of the latent reservoir for HIV-1 in patients receiving valproic acid.

  The Journal of infectious diseases 20070315

• Atypical antipsychotics related metabolic syndrome in bipolar patients.

  Journal of affective disorders 20070301

• Valproate induces widespread epigenetic reprogramming which involves demethylation of specific genes.

  Carcinogenesis 20070301

• Direct determination of valproic acid in biological fluids by capillary electrophoresis with contactless conductivity detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301

• Multiple effects of pentyl-4-yn-VPA enantiomers: from toxicity to short-term memory enhancement.

  Neuropharmacology 20070301

• The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior.

  Molecular pharmacology 20070301

• Adult-onset autosomal dominant myoclonic epilepsy: report of a family with an overlooked epileptic syndrome.

  Seizure 20070301

• Distinct absorption characteristics of oral formulations of valproic acid/divalproex available in the United States.

  Epilepsy research 20070301

• Observations on juvenile myoclonic epilepsy amongst ethnic Bengalees in West Bengal--an Eastern Indian State.

  Seizure 20070301

• A 6-month longitudinal study of bone mineral density with antiepileptic drug monotherapy.

  Epilepsy & behavior : E&B 20070301

• Valproic acid aggravates epilepsy due to MELAS in a patient with an A3243G mutation of mitochondrial DNA.

  Metabolic brain disease 20070301

• Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.

  Experimental brain research 20070301

• Regulation of the HIF-1alpha stability by histone deacetylases.

  Oncology reports 20070301

• Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines.

  International journal of oncology 20070301

• Down-regulation of ERK but not MEK phosphorylation in cultured endothelial cells by repeated changes in cyclic stretch.

  Cardiovascular research 20070301

• Case report: valproic Acid and risperidone treatment leading to development of hyperammonemia and mania.

  Journal of the American Academy of Child and Adolescent Psychiatry 20070301

• Drug-induced Brugada syndrome with ST-T wave alternans and long QT.

  Internal medicine journal 20070301

• Safety of rapid intravenous loading of valproate.

  Epilepsia 20070301

• Endocrine effects of valproate in adolescent girls with epilepsy.

  Epilepsia 20070301

• Psychic disturbances associated with sodium valproate plus levetiracetam.

  The Annals of pharmacotherapy 20070301

• Investigation of low levels of plasma valproic acid concentration following simultaneous administration of sodium valproate and rizatriptan benzoate.

  The Journal of pharmacy and pharmacology 20070301

• Images in hematology. Beyond the wide blue sea.

  Blood 20070301

• Polypharmacy and suicide attempts in bipolar disorder.

  Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20070301

• Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20070301

• Sodium valproate vs phenytoin in status epilepticus: a pilot study.

  Neurology 20070227

• Role of glutathione in neuroprotective effects of mood stabilizing drugs lithium and valproate.

  Neuroscience 20070223

• Sporadic case of spinocerebellar ataxia type 17: treatment observations for managing urinary and psychotic symptoms.

  Movement disorders : official journal of the Movement Disorder Society 20070215

• Thrombospondin-1 peptide ABT-510 combined with valproic acid is an effective antiangiogenesis strategy in neuroblastoma.

  Cancer research 20070215

• Sodium-myo-inositol co-transporter (SMIT-1) mRNA is increased in neutrophils of patients with bipolar 1 disorder and down-regulated under treatment with mood stabilizers.

  The international journal of neuropsychopharmacology 20070201

• Divalproex utility in bipolar disorder with co-occurring cocaine dependence: a pilot study.

  Addictive behaviors 20070201

• Movement disorders in patients taking anticonvulsants.

  Journal of neurology, neurosurgery, and psychiatry 20070201

• Reproductive endocrine function in women with epilepsy: the role of epilepsy type and medication.

  Epilepsy & behavior : E&B 20070201

• The histone deacetylase inhibitor valproic acid potently augments gemtuzumab ozogamicin-induced apoptosis in acute myeloid leukemic cells.

  Leukemia 20070201

• Abnormality of circadian rhythm accompanied by an increase in frontal cortex serotonin in animal model of autism.

  Neuroscience research 20070201

• Acute and chronic effects of carbamazepine, phenytoin, valproate and vinpocetine on BAEP parameters and threshold in the guinea pig.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20070201

• In vivo apoptosis of CD8(+) lymphocytes in acute myeloid leukemia patients: involvement of soluble HLA-I and Fas ligand.

  Leukemia 20070201

• Valproic acid induces apoptosis, p16INK4A upregulation and sensitization to chemotherapy in human melanoma cells.

  Cancer biology & therapy 20070201

• Oral contraceptive administration prevents relapse of periodic psychosis with hyperprolactinemia.

  Psychiatry and clinical neurosciences 20070201

• Lamotrigine added to valproate successfully treated a case of ultra-rapid cycling bipolar disorder.

  Psychiatry and clinical neurosciences 20070201

• Valproic acid and bleeding: caution required.

  The Annals of thoracic surgery 20070201

• Cognitive functioning and instrumental activities of daily living in late-life bipolar disorder.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20070201

• Safety of rapid intravenous valproate infusion in pediatric patients.

  Pediatric neurology 20070201

• Myoclonic-astatic epilepsy in a child with Sturge-Weber syndrome.

  Pediatric neurology 20070201

• Myoclonic seizures in a patient with Charcot-Marie-tooth disease.

  Pediatric neurology 20070201

• Juvenile absence epilepsy exacerbated by valproic acid.

  Pediatric neurology 20070201

• Safety and efficacy of intravenous sodium valproate in the treatment of acute migraine.

  Neuro endocrinology letters 20070201

• Valproic acid-induced hair-texture changes in a white woman.

  Epilepsia 20070201

• Population estimation of the effects of cytochrome P450 2C9 and 2C19 polymorphisms on phenobarbital clearance in Japanese.

  Therapeutic drug monitoring 20070201

• [An experimental study on hepatotoxicity of topiramate in young rats].

  Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20070201

• Differentiating bipolar disorder from depression in primary care.

  Cleveland Clinic journal of medicine 20070201

• Health-related quality of life in adolescents with bipolar I disorder.

  Journal of child and adolescent psychopharmacology 20070201

• [Experimental study on the possibility of brain damage induced by chronic treatment with phenobarbital, clonazepam, valproic acid and topiramate in immature rats].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20070201

• Multi-drug overdose risperidone, ziprasidone, valproate, trihexyphenidyl, and clonazepam.

  The Journal of the Association of Physicians of India 20070201

• Severe bleeding complications during antiepileptic treatment with valproic acid in children.

  Neuropediatrics 20070201

• Neurostabilizers for migraine prevention. From dosage administration to patient expectations.

  Advance for nurse practitioners 20070201

• Leukopenia and neutropenia induced by quetiapine.

  Progress in neuro-psychopharmacology & biological psychiatry 20070130

• Therapeutic monitoring of antiepileptic drugs for epilepsy.

  The Cochrane database of systematic reviews 20070124

• [The role of the antiepileptic drugs at the development of the sexual dysfunctions in male epileptic patients].

  Ideggyogyaszati szemle 20070120

• Chronic treatment with mood stabilizers increases membrane GRK3 in rat frontal cortex.

  Biological psychiatry 20070115

• Sub-second adsorptive fast Fourier transform coulometric technique as a novel method for the determination of nanomolar concentrations of sodium valproate in its pharmaceutical preparation in flowing solution systems.

  Biosensors & bioelectronics 20070115

• Discrimination learning and reversal of the conditioned eyeblink reflex in a rodent model of autism.

  Behavioural brain research 20070110

• Pertussis vaccine and infantile spasms.

  Vaccine 20070105

• A novel embryotoxic estimation method of VPA using ES cells differentiation system.

  Biochemical and biophysical research communications 20070105

• Anticonvulsant activity, neural tube defect induction, mutagenicity and pharmacokinetics of a new potent antiepileptic drug, N-methoxy-2,2,3,3-tetramethylcyclopropane carboxamide.

  Epilepsy research 20070101

• Valproic acid is not a substrate for P-glycoprotein or multidrug resistance proteins 1 and 2 in a number of in vitro and in vivo transport assays.

  The Journal of pharmacology and experimental therapeutics 20070101

• A postulated role of garlic organosulfur compounds in prevention of valproic acid hepatotoxicity.

  Medical hypotheses 20070101

• Ginkgo biloba extract: as a novel agent in prevention of valproic acid hepatotoxicity.

  Medical hypotheses 20070101

• Hippocampal 1H MRS in patients with bipolar disorder taking valproate versus valproate plus quetiapine.

  Psychological medicine 20070101

• Valproate-induced Parkinsonism in epilepsy patients.

  Movement disorders : official journal of the Movement Disorder Society 20070101

• Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect.

  Birth defects research. Part A, Clinical and molecular teratology 20070101

• A placebo-controlled trial of valproate for agitation and aggression in Alzheimer's disease.

  Dementia and geriatric cognitive disorders 20070101

• Medroxyprogesterone - valproic acid - aspirin. MVA regime to reduce transfusion associated mortality in late-term hemoglobinopathies. Hypothesis and rationale.

  Medical hypotheses 20070101

• The effects of carbamazepine, valproic acid and phenobarbital on the oxidative and antioxidative balance in epileptic children.

  European neurology 20070101

• Spectrum of effectiveness of valproate in neuropsychiatry.

  Expert review of neurotherapeutics 20070101

• Meropenem -valproic acid interaction in patients with cefepime-associated status epilepticus.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070101

• Valproic Acid: second generation.

  Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101

• [Valproate sodium and zonisamide associated interstitial pneumonitis in an infant].

  No to hattatsu = Brain and development 20070101

• Effects of valproate on acylcarnitines in children with epilepsy using ESI-MS/MS.

  Epilepsia 20070101

• Photosensitive benign myoclonic epilepsy in infancy.

  Epilepsia 20070101

• Valproate-associated coagulopathies are frequent and variable in children.

  Epilepsia 20070101

• Effects of valproate on serotonin-induced intracellular calcium mobilization in human platelets.

  Journal of psychiatry & neuroscience : JPN 20070101

• Treatment of compulsive sexual behaviour with clomipramine and valproic acid.

  Clinical drug investigation 20070101

• Characteristics of psychotic patients with foreign accent syndrome.

  The Journal of neuropsychiatry and clinical neurosciences 20070101

• [An association between the FABP2 gene polymorphism and efficacy of valproates].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

• Valproic acid-induced pancreatitis: 16 new cases and a review of the literature.

  Journal of gastroenterology 20070101

• The effects of DNA methylation and histone deacetylase inhibitors on human papillomavirus early gene expression in cervical cancer, an in vitro and clinical study.

  Virology journal 20070101

• Valproic acid improves psychotic agitation without influencing plasma risperidone levels in schizophrenic patients.

  Pharmacopsychiatry 20070101

• Antiepileptic drugs for the treatment of chronic and episodic cluster headache: a review.

  Headache 20070101

• Effect of time, injury, age and ethanol on interpatient variability in valproic acid pharmacokinetics after traumatic brain injury.

  Clinical pharmacokinetics 20070101

• Treatment of agitation and aggression in bipolar mania: efficacy of quetiapine.

  Journal of affective disorders 20070101

• A survey of antiepileptic prescribing to women of childbearing potential in psychiatry.

  Archives of women's mental health 20070101

• Quetiapine in the treatment of acute mania: target dose for efficacious treatment.

  Journal of affective disorders 20070101

• Rates of remission/euthymia with quetiapine in combination with lithium/divalproex for the treatment of acute mania.

  Journal of affective disorders 20070101

• Safety and tolerability of quetiapine in the treatment of acute mania in bipolar disorder.

  Journal of affective disorders 20070101

• Quetiapine in the treatment of acute bipolar mania: efficacy across a broad range of symptoms.

  Journal of affective disorders 20070101

• Valproate is an effective, well-tolerated drug for treatment of status epilepticus/serial attacks in adults.

  Acta neurologica Scandinavica. Supplementum 20070101

• Stevens-Johnson syndrome due to concomitant use of lamotrigine and valproic acid.

  American journal of clinical dermatology 20070101

• Huntington's disease and HDACi: would sulpiride and valproate be of therapeutic value?

  Medical hypotheses 20070101

• Is there a role for valproic acid in the treatment of catatonia?

  The Journal of neuropsychiatry and clinical neurosciences 20070101

• Patau syndrome.

  The Journal of neuropsychiatry and clinical neurosciences 20070101

• Pharmacokinetics of antiepileptic drugs in elderly nursing home residents.

  International review of neurobiology 20070101

• Valproic acid, a molecular lead to multiple regulatory pathways.

  Folia biologica 20070101

• The role of mood stabilisers in the treatment of the depressive facet of bipolar disorders.

  Neuroscience and biobehavioral reviews 20070101

• Clinical case of the late diagnosis of type-II schizencephaly.

  Rural and remote health 20070101

• HDAC inhibitors induce apoptosis in glucocorticoid-resistant acute lymphatic leukemia cells despite a switch from the extrinsic to the intrinsic death pathway.

  The international journal of biochemistry & cell biology 20070101

• GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder.

  Neuroscience and biobehavioral reviews 20070101

• Guidelines for the management of severe traumatic brain injury. XIII. Antiseizure prophylaxis.

  Journal of neurotrauma 20070101

• Temporal lobe epilepsy is a disease of faulty neuronal resonators rather than oscillators, and all seizures are provoked, usually by stress.

  Medical hypotheses 20070101

• Polypharmacy and EPS in a child; a case report.

  Psychopharmacology bulletin 20070101

• Neurointensive care management of raised intracranial pressure caused by severe valproic acid intoxication.

  Neurocritical care 20070101

• A cost-effectiveness decision model for antiepileptic drug treatment in newly diagnosed epilepsy patients.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20070101

• The influence of valproic acid on salivary pH in children with cerebral palsy.

  Special care in dentistry : official publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry 20070101

• Transient decrease in serum albumin concentrations in epileptic children treated with sodium valproate monotherapy.

  Clinical neuropharmacology 20070101

• O6-methylguanine-DNA methyltransferase is downregulated in transformed astrocyte cells: implications for anti-glioma therapies.

  Molecular cancer 20070101

• Effect of histone deacetylase inhibitors on the cell nucleus and nucleolus of leukemic myeloblasts in vitro - a cytochemical study.

  Acta histochemica 20070101

• [Isolated severe neurologic disorders in post-partum: posterior reversible encephalopathy syndrome].

  Annales francaises d'anesthesie et de reanimation 20070101

• [New antiepileptics in development].

  Pharmazie in unserer Zeit 20070101

• [Anticonvulsants in the treatment of bipolar disorder].

  Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20070101

• Sodium valproate stimulates potassium and chloride urinary excretion in rats: gender differences.

  BMC pharmacology 20070101

• Adjunctive treatment of acute mania: a clinical overview.

  Acta psychiatrica Scandinavica. Supplementum 20070101

• A 6-month randomized open-label comparison of continuation of oral atypical antipsychotic therapy or switch to long acting injectable risperidone in patients with bipolar disorder.

  Acta psychiatrica Scandinavica. Supplementum 20070101

• Extended-release formulations for the treatment of epilepsy.

  CNS drugs 20070101

• Clinical trials of amyloid-based therapies for Alzheimer's disease.

  CNS spectrums 20070101

• [Hemoperfusion in the treatment of acute valproic acid intoxication].

  Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20070101

• Effects of valproate on vestibular symptoms and electronystagmographic findings in migraine patients.

  Clinical neuropharmacology 20070101

• Valproate-associated hyperammonemic encephalopathy.

  Journal of the American Board of Family Medicine : JABFM 20070101

• The effect of divalproex sodium on HIV replication in vivo.

  The Journal of neuropsychiatry and clinical neurosciences 20070101

• Effect of valproate derivatives on human brain myo-inositol-1-phosphate (MIP) synthase activity and amphetamine-induced rearing.

  Pharmacological reports : PR 20070101

• Modulation of HLA-G expression.

  Neoplasma 20070101

• Influence of the MTHFR genotype on the rate of malformations following exposure to antiepileptic drugs in utero.

  European journal of medical genetics 20070101

• Ubiquitin-dependent distribution of the transcriptional coactivator p300 in cytoplasmic inclusion bodies.

  Epigenetics 20070101

• Screening for the effects of antiepileptic drugs on short term plasticity using a time efficient bioassay.

  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20070101

• Valproate use in children and adolescents with bipolar disorder.

  CNS drugs 20070101

• A recurrent drug rash with eosinophilia and systemic symptoms.

  Pediatric dermatology 20070101

• Severe phenytoin toxicity in a CYP2C9*3*3 homozygous mutant from India.

  Neurology India 20070101

• Valproate and neuroendocrine changes in relation to women treated for epilepsy and bipolar disorder: a review.

  Current medicinal chemistry 20070101

• Valproic acid as anti-cancer drug.

  Current pharmaceutical design 20070101

• Interaction between valproic acid and carbapenem antibiotics.

  Drug metabolism reviews 20070101

• Quetiapine-induced leucopenia and thrombocytopenia.

  Psychosomatics 20070101

• Valproic acid increases the in vitro effects of nitrosureas on human glioma cell lines.

  Oncology research 20070101

• Clinical pharmacology of parenteral use of antiepileptic drugs.

  Epilepsia 20070101

• The use of valproate and new antiepileptic drugs in status epilepticus.

  Epilepsia 20070101

• [Depakine in the therapy of epilepsy in children and adolescents].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20070101

• [Caffeine and antiepileptic drugs: experimental and clinical data].

  Przeglad lekarski 20070101

• Evaluation of bone mineral density in children receiving carbamazepine or valproate monotherapy.

  Acta paediatrica Taiwanica = Taiwan er ke yi xue hui za zhi 20070101

• Glycine affects valproate hepatotoxicity.

  Research communications in molecular pathology and pharmacology 20070101

• Pentylenetetrazol-induced kindling seizure attenuated by Ginkgo biloba extract (EGb 761) in mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20061230

• Effects of mood stabilizers on the disruption of prepulse inhibition induced by apomorphine or dizocilpine in mice.

  European journal of pharmacology 20061228

• Longitudinal follow-up of reproductive and metabolic features of valproate-associated polycystic ovarian syndrome features: A preliminary report.

  Biological psychiatry 20061215

• Contribution of CYP2C9, CYP2A6, and CYP2B6 to valproic acid metabolism in hepatic microsomes from individuals with the CYP2C9*1/*1 genotype.

  Toxicological sciences : an official journal of the Society of Toxicology 20061201

• Valproate protects dopaminergic neurons in midbrain neuron/glia cultures by stimulating the release of neurotrophic factors from astrocytes.

  Molecular psychiatry 20061201

• Valproic acid, a histone deacetylase inhibitor, is an antagonist for oncolytic adenoviral gene therapy.

  Molecular therapy : the journal of the American Society of Gene Therapy 20061201

• Valproic acid and chromatin remodeling in schizophrenia and bipolar disorder: preliminary results from a clinical population.

  Schizophrenia research 20061201

• Capillary microscopy and hemorheology in children during antiepileptic monotherapy with carbamazepine and valproate.

  Seizure 20061201

• The effects of valproate exposure in utero on behavior and the need for educational support in school-aged children.

  Epilepsy & behavior : E&B 20061201

• Oral rapid loading of valproic acid--an alternative to the usual saturation scheme?

  Seizure 20061201

• Valproic acid-induced fetal malformations are reduced by maternal immune stimulation with granulocyte-macrophage colony-stimulating factor or interferon-gamma.

  The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 20061201

• Acute treatment of mania: an update on new medications.

  Current psychiatry reports 20061201

• Alpers syndrome: progressive neuronal degeneration of children with liver disease.

  Developmental medicine and child neurology 20061201

• Appropriateness of plasma level determinations for lithium and valproate in routine care of psychiatric inpatients with affective disorders.

  Journal of clinical psychopharmacology 20061201

• [Diagnosis and treatment in a case of respiratory myoclonus].

  Revista de neurologia 20061201

• Lamotrigine combined with divalproex or lithium for bipolar disorder: a case series.

  CNS spectrums 20061201

• Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: update 2007.

  Bipolar disorders 20061201

• Valproate hepatotoxicity in a 5-year-old boy with cerebral palsy due to neonatal asphyxia.

  Pediatrics international : official journal of the Japan Pediatric Society 20061201

• Valproate and delta-sleep peptide display high efficacy against metaphit-induced audiogenic seizure in rats.

  Acta physiologica Hungarica 20061201

• Loss of autonomy related to valproic acid intake.

  Journal of the American Geriatrics Society 20061201

• Evaluation of renal tubular function in children taking anti-epileptic treatment.

  Nephrology (Carlton, Vic.) 20061201

• The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s).

  Journal of child and adolescent psychopharmacology 20061201

• The challenges of psychopharmacological management of children with severe developmental disabilities.

  Journal of child and adolescent psychopharmacology 20061201

• Valproic acid-induced hepatopathy: nine new fatalities in Germany from 1994 to 2003.

  Epilepsia 20061201

• Influence of major antiepileptic drugs on attention, reaction time, and speed of information processing: results from a randomized, double-blind, placebo-controlled withdrawal study of seizure-free epilepsy patients receiving monotherapy.

  Epilepsia 20061201

• Lack of efficacy and potential aggravation of myoclonus with lamotrigine in Unverricht-Lundborg disease.

  Epilepsia 20061201

• The frequency of reversible parkinsonism and cognitive decline associated with valproate treatment: a study of 364 patients with different types of epilepsy.

  Epilepsia 20061201

• New Alzheimer's clinical trials to be undertaken by NIA nationwide consortium.

  American journal of Alzheimer's disease and other dementias 20061201

• Effect of valproic acid, a histone deacetylase inhibitor, on cell death and molecular changes caused by low-dose irradiation.

  Annals of the New York Academy of Sciences 20061201

• Efficacy of carbamazepine and valproate as monotherapy for early epilepsy and single seizures.

  Neurology 20061128

• Phase 1/2 study of the combination of 5-aza-2'-deoxycytidine with valproic acid in patients with leukemia.

  Blood 20061115

• Brain pseudoatrophy and mental regression on valproate and a mitochondrial DNA mutation.

  Neurology 20061114

• Valproic acid inhibits invasiveness in bladder cancer but not in prostate cancer cells.

  The Journal of pharmacology and experimental therapeutics 20061101

• Valproate and copper accelerate TRH-like peptide synthesis in male rat pancreas and reproductive tissues.

  Peptides 20061101

• Establishing a standardized therapeutic testing protocol for spinal muscular atrophy.

  Neurobiology of disease 20061101

• Hepatotoxicity and valproate therapy.

  Internal medicine journal 20061101

• Valproate-induced chorea and encephalopathy in atypical nonketotic hyperglycinemia.

  Pediatric neurology 20061101

• An interaction between aspirin and valproate: the relevance of plasma protein displacement drug-drug interactions.

  The American journal of psychiatry 20061101

• Valproic acid induces apoptosis in prostate carcinoma cell lines by activation of multiple death pathways.

  Anti-cancer drugs 20061101

• [Reintroduction of treatment with lamotrigine in combination with valproate after an initial allergic skin reaction].

  Revue neurologique 20061101

• [Exacerbation of tonicoclonic seizures in a juvenile myoclonic epileptic taking lamotrigine].

  Revue neurologique 20061101

• Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells.

  The Journal of endocrinology 20061101

• Oxidative stress in children receiving valproic acid.

  The Journal of pediatrics 20061101

• Characterization of the anticonvulsant, behavioral and pharmacokinetic interaction profiles of stiripentol in combination with clonazepam, ethosuximide, phenobarbital, and valproate using isobolographic analysis.

  Epilepsia 20061101

• The evaluation of thyroid functions, thyroid antibodies, and thyroid volumes in children with epilepsy during short-term administration of oxcarbazepine and valproate.

  Epilepsia 20061101

• How to replace lamotrigine with valproate.

  Epilepsia 20061101

• Anticonvulsant hypersensitivity syndrome: cross-reactivity with tricyclic antidepressant agents.

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101

• Casting a broad network: fishing for mechanisms of retinoid teratogenicity.

  Toxicological sciences : an official journal of the Society of Toxicology 20061101

• [Determination of serum valproic acid drugs by capillary electrophoresis].

  Klinicheskaia laboratornaia diagnostika 20061101

• Adjunctive topiramate therapy in patients receiving a mood stabilizer for bipolar I disorder: a randomized, placebo-controlled trial.

  The Journal of clinical psychiatry 20061101

• Effect of chronic consumption of sodium valproate and melatonin on seizure activity in Krushinskii-Molodkina rats.

  Bulletin of experimental biology and medicine 20061101

• [A severe case of interstitial nephritis caused by sodium valproate].

  Ugeskrift for laeger 20061023

• Epigenetic cancer therapy makes headway.

  Journal of the National Cancer Institute 20061018

• Arachidonyl-2'-chloroethylamide, a highly selective cannabinoid CB1 receptor agonist, enhances the anticonvulsant action of valproate in the mouse maximal electroshock-induced seizure model.

  European journal of pharmacology 20061010

• Valproate effects on kinetics of lamotrigine in pregnancy and treatment with oral contraceptives.

  Neurology 20061010

• Serum total amylase, pancreatic amylase and lipase activities in epileptic children treated with sodium valproate monotherapy.

  Brain & development 20061001

• Carbamazepine and valproate for the treatment of bipolar disorder: a review of the literature.

  Journal of affective disorders 20061001

• Protein C, protein S and other pro- and anticoagulant activities among epileptic children using sodium valproate.

  Brain & development 20061001

• Early effect of sodium valproate and carbamazepine monotherapy on homocysteine metabolism in children with epilepsy.

  Epilepsy research 20061001

• The antiepileptic and anticancer agent, valproic acid, induces P-glycoprotein in human tumour cell lines and in rat liver.

  British journal of pharmacology 20061001

• Conventional and sustained-release valproate in children with newly diagnosed epilepsy: a randomized and crossover study comparing clinical effects, patient preference and pharmacokinetics.

  European journal of clinical pharmacology 20061001

• Parietal lobe source localization and sensitivity to hyperventilation in a patient with subclinical rhythmic electrographic discharges of adults (SREDA).

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20061001

• Efficacy of topiramate, valproate, and their combination on aggression/agitation behavior in patients with psychosis.

  Journal of clinical psychopharmacology 20061001

• Functional and morphological recovery of dystrophic muscles in mice treated with deacetylase inhibitors.

  Nature medicine 20061001

• Noninvasive capnometry for continuous monitoring of mental status: a tale of 2 patients.

  The American journal of emergency medicine 20061001

• Acute encephalopathy after intravenous administration of valproate in non-convulsive status epilepticus.

  European journal of neurology 20061001

• Combined treatment of pediatric high-grade glioma with the oncolytic viral strain MTH-68/H and oral valproic acid.

  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20061001

• Clinical inquiries. What are effective treatments for oppositional defiant behaviors in adolescents?

  The Journal of family practice 20061001

• The spectrum of valproic acid-associated pancreatitis.

  Pediatrics 20061001

• The effects of chronic valproate and diazepam in a mouse model of posttraumatic stress disorder.

  Pharmacology, biochemistry, and behavior 20061001

• Measuring unbound versus total valproate concentrations for therapeutic drug monitoring.

  Therapeutic drug monitoring 20061001

• Placebo-level incidence of extrapyramidal symptoms (EPS) with quetiapine in controlled studies of patients with bipolar mania.

  Bipolar disorders 20061001

• Carnitine does not improve weight loss outcomes in valproate-treated bipolar patients consuming an energy-restricted, low-fat diet.

  Bipolar disorders 20061001

• Autonomic headache with autonomic seizures: a case report.

  The journal of headache and pain 20061001

• Valproic acid does not affect markers of human immunodeficiency virus disease progression.

  Journal of neurovirology 20061001

• Fetal valproate syndrome.

  Indian journal of pediatrics 20061001

• A randomized, placebo-controlled, multicenter study of divalproex sodium extended release in the treatment of acute mania.

  The Journal of clinical psychiatry 20061001

• Pharmacological prevention of migraine: to be considered case by case.

  Prescrire international 20061001

• [The inhibition of CYP2C9 isoenzyme in Cunninghamella blakesleeana AS 3. 910].

  Yao xue xue bao = Acta pharmaceutica Sinica 20061001

• [Ca2+/calmodulin-dependent protein kinase II--a target for sodium valproate?].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20061001

• Histone proteins determined in a human colon cancer by high-performance liquid chromatography and mass spectrometry.

  Journal of chromatography. A 20060929

• Valproate prevents MK801-induced changes in brain-derived neurotrophic factor mRNA in the rat brain.

  European journal of pharmacology 20060918

• Adenomatous polyposis coli determines sensitivity to histone deacetylase inhibitor-induced apoptosis in colon cancer cells.

  Cancer research 20060915

• Novel valproic acid derivatives with potent differentiation-inducing activity in myeloid leukemia cells.

  Leukemia research 20060901

• Serum and liver tissue biotinidase enzyme activity in rats which were administrated to valproic acid.

  Brain & development 20060901

• Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos.

  European journal of nutrition 20060901

• A case of pancytopenia.

  Journal of psychopharmacology (Oxford, England) 20060901

• Antiepileptic drug use and birth rate in patients with epilepsy--a population-based cohort study in Finland.

  Human reproduction (Oxford, England) 20060901

• The neuroprotective agent, valproic acid, regulates the mitogen-activated protein kinase pathway through modulation of protein kinase A signalling in Dictyostelium discoideum.

  European journal of cell biology 20060901

• Valproic acid induced encephalopathy--19 new cases in Germany from 1994 to 2003--a side effect associated to VPA-therapy not only in young children.

  Seizure 20060901

• Treatment with valproate after status epilepticus: effect on neuronal damage, epileptogenesis, and behavioral alterations in rats.

  Neuropharmacology 20060901

• Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes.

  Epilepsy research 20060901

• Total phenytoin concentrations do not accurately predict free phenytoin concentrations in critically ill children.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060901

• Preclinical evaluation of 2,2,3,3-tetramethylcyclopropanecarbonyl-urea, a novel, second generation to valproic acid, antiepileptic drug.

  Neuropharmacology 20060901

• Polydipsia with normal natremia induced by Valproic Acid.

  The Australian and New Zealand journal of psychiatry 20060901

• Mood stabilizer prescribing in a Christchurch adolescent sample: does it comply with guidelines?

  Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20060901

• A case of schizophrenia with complete agenesis of the corpus callosum.

  Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists 20060901

• Adverse effects of antiepileptic drugs on bone mineral density.

  Pediatric neurology 20060901

• Nonconvulsive status epilepticus and neurodevelopmental delay.

  Pediatric neurology 20060901

• Valproic acid enhances the efficacy of chemotherapy in EBV-positive tumors by increasing lytic viral gene expression.

  Cancer research 20060901

• Sequential valproic acid/all-trans retinoic acid treatment reprograms differentiation in refractory and high-risk acute myeloid leukemia.

  Cancer research 20060901

• Effects of lithium and valproate on amphetamine-induced oxidative stress generation in an animal model of mania.

  Journal of psychiatry & neuroscience : JPN 20060901

• An automatic procedure for evaluation of single cell motility.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060901

• Characterization of insulin secretion in Valproate-treated patients with epilepsy.

  Epilepsia 20060901

• Increased apparent oral clearance of valproic acid during intake of combined contraceptive steroids in women with epilepsy.

  Epilepsia 20060901

• Comparison of reproductive effects of levetiracetam and valproate studied in prepubertal porcine ovarian follicular cells.

  Epilepsia 20060901

• Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells.

  Molecular cancer therapeutics 20060901

• Maintenance treatment of bipolar disorder: Applying research to clinical practice.

  Journal of psychiatric practice 20060901

• Epilepsy and polycystic ovary syndrome: where is the link?

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20060901

• Valproate induced isolated neutropenia.

  Indian journal of pediatrics 20060901

• Serum lipid profile in children receiving anti-epileptic drug monotherapy: is it atherogenic?

  Journal of pediatric endocrinology & metabolism : JPEM 20060901

• Sustained attention deficits in manic and euthymic patients with bipolar disorder.

  Progress in neuro-psychopharmacology & biological psychiatry 20060830

• Effects of oxcarbazepine on cognitive function in children and adolescents with partial seizures.

  Neurology 20060822

• Antileukemia activity of the combination of an anthracycline with a histone deacetylase inhibitor.

  Blood 20060815

• Valproate may improve strength and function in patients with type III/IV spinal muscle atrophy.

  Neurology 20060808

• In utero antiepileptic drug exposure: fetal death and malformations.

  Neurology 20060808

• Effects of chronic administration of olanzapine, amitriptyline, haloperidol or sodium valproate in naive and anhedonic rats.

  The international journal of neuropsychopharmacology 20060801

• Toward refinement of the colony-forming unit-granulocyte/macrophage clonogenic assay: inclusion of a metabolic system.

  Toxicology in vitro : an international journal published in association with BIBRA 20060801

• Favorable response of ADHD with giant SEP to extended-release valproate.

  Brain & development 20060801

• A new neurobehavioral model of autism in mice: pre- and postnatal exposure to sodium valproate.

  Journal of autism and developmental disorders 20060801

• [Neuropsychological outcome following intrauterine exposure to valproate].

  Der Nervenarzt 20060801

• The influence of old age and enzyme inducing comedication on the pharmacokinetics of valproic acid at steady-state: A case-matched evaluation based on therapeutic drug monitoring data.

  Epilepsy research 20060801

• Add-on lamotrigine treatment and plasma glutamate levels in epilepsy: relation to treatment response.

  Epilepsy research 20060801

• Quantitative EEG effects of carbamazepine, oxcarbazepine, valproate, lamotrigine, and possible clinical relevance of the findings.

  Epilepsy research 20060801

• Early and persistent increase in serum lipoprotein (a) concentrations in epileptic children treated with carbamazepine and sodium valproate monotherapy.

  Epilepsy research 20060801

• Altered expression of beta1 integrins in renal carcinoma cell lines exposed to the differentiation inducer valproic acid.

  International journal of molecular medicine 20060801

• Involvement of recognition and interaction of carnitine transporter in the decrease of L-carnitine concentration induced by pivalic acid and valproic acid.

  Pharmaceutical research 20060801

• A multiphasic absorption model best characterizes gastrointestinal absorption of divalproex sodium extended-release tablets.

  Journal of clinical pharmacology 20060801

• Valproate lowers plasma concentration of olanzapine.

  Journal of clinical psychopharmacology 20060801

• Divalproex versus placebo for the prevention of irritability associated with fluoxetine treatment in autism spectrum disorder.

  Journal of clinical psychopharmacology 20060801

• No change to HIV-1 latency with valproate therapy.

  AIDS (London, England) 20060801

• Oxidative stress in experimental liver microvesicular steatosis: role of mitochondria and peroxisomes.

  Journal of gastroenterology and hepatology 20060801

• Reduced valproate plasma levels possible after introduction of efavirenz in a bipolar patient.

  Bipolar disorders 20060801

• Effect of delayed and/or missed enteric-coated divalproex doses on valproic acid concentrations: simulation and dose replacement recommendations for the clinician.

  Journal of clinical pharmacy and therapeutics 20060801

• Epileptic seizures caused by low valproic acid levels from an interaction with meropenem.

  Journal of clinical pharmacy and therapeutics 20060801

• Valproic Acid prolongs survival time of severe combined immunodeficient mice bearing intracerebellar orthotopic medulloblastoma xenografts.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20060801

• Hippocampal involvement in valproate-induced acute hyperammonemic encephalopathy.

  Archives of neurology 20060801

• Interactions of serum albumin, valproic acid and carbamazepine with the pharmacokinetics of phenytoin in cancer patients.

  Basic & clinical pharmacology & toxicology 20060801

• Reduced suicidal ideation in bipolar I disorder mixed-episode patients in a placebo-controlled trial of olanzapine combined with lithium or divalproex.

  The Journal of clinical psychiatry 20060801

• Synergistic effects of valproic acid and mitomycin C in adenocarcinoma cell lines and fresh tumor cells of patients with colon cancer.

  Journal of chemotherapy (Florence, Italy) 20060801

• Sodium valproate vs phenytoin in status epilepticus: a pilot study.

  Neurology 20060725

• Valproic acid induces caspase 3-mediated apoptosis in microglial cells.

  Neuroscience 20060721

• Haloperidol alone or in combination for acute mania.

  The Cochrane database of systematic reviews 20060719

• Chronic administration of valproic acid inhibits prostate cancer cell growth in vitro and in vivo.

  Cancer research 20060715

• Excitability of the human epileptic cortex after chronic valproate: a reappraisal.

  Brain research 20060712

• Effects of divalproex and atypical antipsychotic drugs on dopamine and acetylcholine efflux in rat hippocampus and prefrontal cortex.

  Brain research 20060712

• Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060712

• Plasma free carnitine in epilepsy children, adolescents and young adults treated with old and new antiepileptic drugs with or without ketogenic diet.

  Brain & development 20060701

• Effect of intracerebroventricular continuous infusion of valproic acid versus single i.p. and i.c.v. injections in the amygdala kindling epilepsy model.

  Epilepsy research 20060701

• Effects of acetylation, polymerase phosphorylation, and DNA unwinding in glucocorticoid receptor transactivation.

  The Journal of steroid biochemistry and molecular biology 20060701

• Valproate blocks high-dose methamphetamine-induced behavioral cross-sensitization to locomotion-inducing effect of dizocilpine (MK-801), but not methamphetamine.

  Psychopharmacology 20060701

• Valproate-induced hyperammonemic encephalopathy.

  Acta neurologica Scandinavica 20060701

• Acute hemolysis with acute renal failure in a patient with valproic acid poisoning treated with charcoal hemoperfusion.

  Hemodialysis international. International Symposium on Home Hemodialysis 20060701

• Valproic acid-induced gene expression through production of reactive oxygen species.

  Cancer research 20060701

• Endocrine and metabolic adverse effects of psychotropic medications in children and adolescents.

  Journal of the American Academy of Child and Adolescent Psychiatry 20060701

• Color vision and macular recovery time in epileptic adolescents treated with valproate and carbamazepine.

  European journal of neurology 20060701

• Disposition of valproic acid in self-poisoned adults.

  Basic & clinical pharmacology & toxicology 20060701

• A comparison of divalproex and oxcarbazepine in aggressive youth with bipolar disorder.

  Journal of psychiatric practice 20060701

• Valproate-associated coagulopathies are frequent and variable in children.

  Epilepsia 20060701

• Risk of aplastic anemia in patients using antiepileptic drugs.

  Epilepsia 20060701

• Chronic valproic acid treatment triggers increased neuropeptide y expression and signaling in rat nucleus reticularis thalami.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060621

• Cellular plasticity cascades: genes-to-behavior pathways in animal models of bipolar disorder.

  Biological psychiatry 20060615

• Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania.

  Life sciences 20060613

• Cytoprotection by lithium and valproate varies between cell types and cellular stresses.

  European journal of pharmacology 20060606

• Behavioral effects of short-term administration of lithium and valproic acid in rats.

  Brain research 20060606

• Altered gene expression in mice treated with the mood stabilizer sodium valproate.

  The international journal of neuropsychopharmacology 20060601

• Adjunctive topiramate in ultradian cycling bipolar disorder: case report with 3-year follow-up.

  European psychiatry : the journal of the Association of European Psychiatrists 20060601

• Valproate is associated with new-onset oligoamenorrhea with hyperandrogenism in women with bipolar disorder.

  Biological psychiatry 20060601

• Cellular plasticity cascades: targets for the development of novel therapeutics for bipolar disorder.

  Biological psychiatry 20060601

• In vitro characterization of lamotrigine N2-glucuronidation and the lamotrigine-valproic acid interaction.

  Drug metabolism and disposition: the biological fate of chemicals 20060601

• In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate.

  Annals of neurology 20060601

• Homeostatic effects of plasma valproate levels on corticospinal excitability changes induced by 1Hz rTMS in patients with juvenile myoclonic epilepsy.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20060601

• Modulation of pentylenetetrazole-induced seizures and oxidative stress parameters by sodium valproate in the absence and presence of N-acetylcysteine.

  Fundamental & clinical pharmacology 20060601

• Lipids, lipoproteins, apolipoproteins, selected trace elements and minerals in the serum of children on valproic acid monotherapy.

  Basic & clinical pharmacology & toxicology 20060601

• Much improved outcome with gabapentin-divalproex combination in adults with bipolar disorders and developmental disabilities.

  Journal of clinical psychopharmacology 20060601

• Valproic acid prevents brain injury in a canine model of hypothermic circulatory arrest: a promising new approach to neuroprotection during cardiac surgery.

  The Annals of thoracic surgery 20060601

• New antiepileptic drugs that are second generation to existing antiepileptic drugs.

  Expert opinion on investigational drugs 20060601

• Molecular approaches to developmental malformations using analogous forms of valproic acid.

  Congenital anomalies 20060601

• Synergistic induction of folate receptor beta by all-trans retinoic acid and histone deacetylase inhibitors in acute myelogenous leukemia cells: mechanism and utility in enhancing selective growth inhibition by antifolates.

  Cancer research 20060601

• Teratology study of derivatives of tetramethylcyclopropyl amide analogues of valproic acid in mice.

  Birth defects research. Part B, Developmental and reproductive toxicology 20060601

• Divalproex sodium reduces overall aggression in youth at high risk for bipolar disorder.

  Journal of child and adolescent psychopharmacology 20060601

• Preliminary study of relationships among measures of depressive symptoms in adolescents with bipolar disorder.

  Journal of child and adolescent psychopharmacology 20060601

• Does it really matter when a blood sample for valproic acid concentration is taken following once-daily administration of divalproex-ER?

  Therapeutic drug monitoring 20060601

• Diamond-Blackfan anemia in remission for 2 years on valproic acid.

  Haematologica 20060601

• Occipital intermittent rhythmic delta activity in absence epilepsy.

  Arquivos de neuro-psiquiatria 20060601

• The effect of valproate on silent period and corticomotor excitability.

  Epileptic disorders : international epilepsy journal with videotape 20060601

• Comparison of valporic acid efficacy in familial versus sporadic cases of juvenile myoclonic epilepsy.

  Neurology India 20060601

• Hypomania as an aura in migraine.

  Neurology India 20060601

• Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation.

  Neoplasia (New York, N.Y.) 20060601

• Lithium increases nerve growth factor levels in the rat hippocampus in an animal model of mania.

  Behavioural pharmacology 20060601

• Potentiation of the anticancer effect of valproic acid, an antiepileptic agent with histone deacetylase inhibitory activity, by the kinase inhibitor Staurosporine or its clinically relevant analogue UCN-01.

  British journal of cancer 20060522

• [Epilepsy and male sexual dysfunction: etiology, diagnosis and therapy].

  Ideggyogyaszati szemle 20060520

• Predicted plasma valproic acid concentrations in patients missing and replacing a full daily dose of extended-release divalproex sodium.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060515

• HDAC inhibition is associated to valproic acid induction of early megakaryocytic markers.

  Experimental cell research 20060515

• Picrotoxin blocks the anxiolytic- and panicolytic-like effects of sodium valproate in the rat elevated T-maze.

  European journal of pharmacology 20060510

• Prenatal exposure to antiepileptic drugs.

  Lancet (London, England) 20060506

• Role of site-specific binding to plasma albumin in drug availability to brain.

  The Journal of pharmacology and experimental therapeutics 20060501

• [Transient central diabetes insipidus during a valproic acid poisoning].

  Annales francaises d'anesthesie et de reanimation 20060501

• Neuropsychiatric profiles of patients with juvenile myoclonic epilepsy treated with valproate or topiramate.

  Epilepsy & behavior : E&B 20060501

• Absence of convulsive liability of doripenem, a new carbapenem antibiotic, in comparison with beta-lactam antibiotics.

  Toxicology 20060501

• Multiple mechanisms underlying the neuroprotective effects of antiepileptic drugs against in vitro ischemia.

  Stroke 20060501

• Fatal cerebral edema from late-onset ornithine transcarbamylase deficiency in a juvenile male patient receiving valproic acid.

  Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 20060501

• Effects of drugs acting on the GABA-benzodiazepine receptor complex on flurothyl-induced seizures in Mongolian gerbils.

  European journal of pharmacology 20060501

• Insulin-related metabolic changes during treatment with valproate in patients with epilepsy.

  Epilepsy & behavior : E&B 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Safety and tolerability of mood-stabilising anticonvulsants in the elderly.

  Expert opinion on drug safety 20060501

• Novel valproic acid derivatives with hemoglobin F inducing activity.

  American journal of hematology 20060501

• Facilitation action of N-acetylcysteine on the anticonvulsant effect of sodium valproate in mice.

  Basic & clinical pharmacology & toxicology 20060501

• Less is more: inpatient management of a child with complex pharmacotherapy.

  Journal of the American Academy of Child and Adolescent Psychiatry 20060501

• Anticonvulsant treatment for psychiatric and seizure indications among youths.

  Psychiatric services (Washington, D.C.) 20060501

• Conversion from delayed-release sodium valproate to extended-release sodium valproate: initial results and long-term follow-up.

  Epilepsy & behavior : E&B 20060501

• Anticonvulsants in bipolar disorder.

  The Australian and New Zealand journal of psychiatry 20060501

• The rational use of medications in acute psychotic presentations -- the case for less is more.

  Journal of psychiatry & neuroscience : JPN 20060501

• [Polycystic ovary syndrome and hepatocellular adenoma related to long-term use of sodium valproate in a young woman].

  No to hattatsu = Brain and development 20060501

• Transient occipitotemporal subcortical diffusion-weighted magnetic resonance imaging abnormalities associated with status epilepticus. Case report.

  Neurologia medico-chirurgica 20060501

• Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour.

  Proceedings. Biological sciences 20060422

• Antimyoclonic effect of levetiracetam in MERRF syndrome.

  Journal of the neurological sciences 20060415

• Histone hyperacetylation is associated with amelioration of experimental colitis in mice.

  Journal of immunology (Baltimore, Md. : 1950) 20060415

• Major malformations with valproic acid.

  Canadian family physician Medecin de famille canadien 20060410

• Simultaneous determination of mycophenolic acid and valproic acid based on derivatization by high-performance liquid chromatography with fluorescence detection.

  Biomedical chromatography : BMC 20060401

• Divalproex sodium vs. placebo in the treatment of repetitive behaviours in autism spectrum disorder.

  The international journal of neuropsychopharmacology 20060401

• Valproic acid increases conservative homologous recombination frequency and reactive oxygen species formation: a potential mechanism for valproic acid-induced neural tube defects.

  Molecular pharmacology 20060401

• S-2-pentyl-4-pentynoic hydroxamic acid and its metabolite s-2-pentyl-4-pentynoic acid in the NMRI-exencephaly-mouse model: pharmacokinetic profiles, teratogenic effects, and histone deacetylase inhibition abilities of further valproic acid hydroxamates and amides.

  Drug metabolism and disposition: the biological fate of chemicals 20060401

• Acute myelogenous leukemia in a patient with Li-Fraumeni syndrome treated with valproic acid, theophyllamine and all-trans retinoic acid: a case report.

  Leukemia 20060401

• Azolylchromans as a novel scaffold for anticonvulsant activity.

  Bioorganic & medicinal chemistry letters 20060401

• Screening for bipolar disorder in women with polycystic ovary syndrome: a pilot study.

  Journal of affective disorders 20060401

• Sodium- and magnesium-valproate in vivo modulate glutamatergic and GABAergic synapses in the medial prefrontal cortex.

  Psychopharmacology 20060401

• Inositol augmentation of lithium or valproate for bipolar depression.

  Bipolar disorders 20060401

• Comparative absorption profiles of divalproex sodium delayed-release versus extended-release tablets -- clinical implications.

  The Annals of pharmacotherapy 20060401

• Absence epilepsy associated with moyamoya disease. Case report.

  Journal of neurosurgery 20060401

• [Effect of N-acetyl-cysteine and depakine pretreatment on ferrous chloride-induced membrane potential and peroxidate changes in rat cortex neurons].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060401

• Cognitive functioning in bipolar patients receiving lamotrigine: preliminary results.

  Journal of clinical psychopharmacology 20060401

• Comparison of the effect of topiramate and sodium valporate in migraine prevention: a randomized blinded crossover study.

  Headache 20060401

• Retinal nerve fiber layer and macular thickness in adolescents with epilepsy treated with valproate and carbamazepine.

  Epilepsia 20060401

• Valproic acid prevents hemorrhage-associated lethality and affects the acetylation pattern of cardiac histones.

  Shock (Augusta, Ga.) 20060401

• Effect of carbamezapine and valproic acid on bone mineral density, IGF-I and IGFBP-3.

  Journal of pediatric endocrinology & metabolism : JPEM 20060401

• Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report.

  Neurology 20060328

• Chronic valproate fails to prevent imipramine-induced behavioural sensitization to the dopamine D2-like receptor agonist quinpirole.

  European journal of pharmacology 20060327

• Folic acid and pantothenic acid protection against valproic acid-induced neural tube defects in CD-1 mice.

  Toxicology and applied pharmacology 20060301

• Valproic acid induces extracellular signal-regulated kinase 1/2 activation and inhibits apoptosis in endothelial cells.

  Cell death and differentiation 20060301

• Dysmorphic features: an important clue to the diagnosis and severity of fetal anticonvulsant syndromes.

  Archives of disease in childhood. Fetal and neonatal edition 20060301

• FLT3-ITD-, but not BCR/ABL-transformed cells require concurrent Akt/mTor blockage to undergo apoptosis after histone deacetylase inhibitor treatment.

  Blood 20060301

• Plasma clozapine levels and clinical response in treatment-refractory Chinese schizophrenic patients.

  Progress in neuro-psychopharmacology & biological psychiatry 20060301

• Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6.

  Seizure 20060301

• Influence of age, gender, body weight and valproate comedication on quetiapine plasma concentrations.

  International clinical psychopharmacology 20060301

• Inhibition of retinoic acid receptor signaling by Ski in acute myeloid leukemia.

  Leukemia 20060301

• Valproate enhances imatinib-induced growth arrest and apoptosis in chronic myeloid leukemia cells.

  Cancer 20060301

• Every-12-hour administration of extended-release divalproex in patients with epilepsy: impact on plasma valproic acid concentrations.

  Epilepsy & behavior : E&B 20060301

• Anticonvulsants in the treatment of bipolar mania.

  Expert opinion on pharmacotherapy 20060301

• Detecting vigabatrin toxicity by imaging of the retinal nerve fiber layer.

  Investigative ophthalmology & visual science 20060301

• Valproic acid management of acute alcohol withdrawal.

  The Annals of pharmacotherapy 20060301

• [Pharmacotherapy of manic-depressive mixed States].

  Psychiatrische Praxis 20060301

• Myo-inositol enhances teratogenicity of valproic acid in the mouse.

  Birth defects research. Part A, Clinical and molecular teratology 20060301

• Ultrastructural investigation of the protective role of folic acid and vitamin E against toxic effects of valproic acid on maternal liver tissue during period of gestation.

  Saudi medical journal 20060301

• A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania.

  Journal of the American Academy of Child and Adolescent Psychiatry 20060301

• The effects of valproic acid, vitamin E and folic acid on ribs of rat fetuses in the prenatal period.

  Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20060301

• Relapse prevention in bipolar disorder: a critical review of current guidelines.

  Journal of psychopharmacology (Oxford, England) 20060301

• EEG and seizure exacerbation induced by carbamazepine in Panayiotopoulos syndrome.

  Epileptic disorders : international epilepsy journal with videotape 20060301

• [Embryopathy due to valproic acid with severe malformations in the central nervous system].

  Revista de neurologia 20060301

• HDAC inhibitor treatment of hepatoma cells induces both TRAIL-independent apoptosis and restoration of sensitivity to TRAIL.

  Hepatology (Baltimore, Md.) 20060301

• Recent advances on neural tube defects with special reference to Valproic Acid.

  Endocrine, metabolic & immune disorders drug targets 20060301

• Valproic acid promotes neurite outgrowth in PC12 cells independent from regulation of the survival of motoneuron protein.

  Chemical biology & drug design 20060301

• Effect of valproic acid and antiapoptotic cytokines on differentiation and apoptosis induction of human leukemia cells.

  General physiology and biophysics 20060301

• Effects of anticonvulsant therapy on vitamin D status in children: prospective monitoring study.

  Journal of child neurology 20060301

• 2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice.

  European journal of pharmacology 20060215

• 1-Methyl-1,2,3,4-tetrahydroisoquinoline enhances the anticonvulsant action of carbamazepine and valproate in the mouse maximal electroshock seizure model.

  Neuropharmacology 20060201

• Suppression of adiponectin gene expression by histone deacetylase inhibitor valproic acid.

  Endocrinology 20060201

• Construction and evaluation of PVC and sol-gel sensor membranes based on Mn(III)TPP-Cl. Application to valproate determination in pharmaceutical preparations.

  Analytical and bioanalytical chemistry 20060201

• Possible precipitation of myoclonic seizures with oxcarbazepine.

  Epilepsy & behavior : E&B 20060201

• Frequency of epileptiform EEG abnormalities in a sequential screening of autistic patients with no known clinical epilepsy from 1996 to 2005.

  Epilepsy & behavior : E&B 20060201

• A double-blind, placebo-controlled trial of adjunctive donepezil in treatment-resistant mania.

  Bipolar disorders 20060201

• Pharmacokinetic profile of an oral loading dose of divalproex sodium during acute alcohol withdrawal.

  Journal of clinical psychopharmacology 20060201

• Post-anoxic myoclonus: a case presentation and review of management in the rehabilitation setting.

  Brain injury 20060201

• Combination lithium and divalproex sodium in pediatric bipolar symptom re-stabilization.

  Journal of the American Academy of Child and Adolescent Psychiatry 20060201

• What is bipolar disorder?

  The American journal of psychiatry 20060201

• Risk and resilience markers in bipolar disorder: brain responses to emotional challenge in bipolar patients and their healthy siblings.

  The American journal of psychiatry 20060201

• Linear relationship of valproate serum concentration to response and optimal serum levels for acute mania.

  The American journal of psychiatry 20060201

• Neurocognitive function in unmedicated manic and medicated euthymic pediatric bipolar patients.

  The American journal of psychiatry 20060201

• Pisa syndrome in a patient in a wheelchair taking valproic acid.

  The American journal of psychiatry 20060201

• The effects of the histone deacetylase inhibitor valproic acid on cell cycle, growth suppression and apoptosis in multiple myeloma.

  Haematologica 20060201

• [A retrospective study comparing two formulations of valproic acid].

  Revista de neurologia 20060201

• Treatment considerations for patients experiencing rapid-cycling bipolar disorder.

  Perspectives in psychiatric care 20060201

• Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives.

  Chemical research in toxicology 20060201

• Influence of lamotrigine and topiramate on MDR1 expression in difficult-to-treat temporal lobe epilepsy.

  Epilepsia 20060201

• Benign myoclonic epilepsy in infants: electroclinical features and long-term follow-up of 34 patients.

  Epilepsia 20060201

• Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.

  Epilepsia 20060201

• Epilepsy with myoclonic absences.

  Indian journal of pediatrics 20060201

• Development of sustained-release tablets containing sodium valproate: in vitro and in vivo correlation.

  Drug development and industrial pharmacy 20060201

• CACNA1A mutation in a EA-2 patient responsive to acetazolamide and valproic acid.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20060201

• [Inhibition of proliferation and induction of apoptosis and differentiation of leukemic cell line HL-60 by sodium valproate].

  Zhongguo shi yan xue ye xue za zhi 20060201

• [Migraine therapy].

  Der Internist 20060201

• A case of fetal anticonvulsant syndrome with severe bilateral upper limb defect.

  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20060201

• Development and validation of a sensitive assay of valproic acid in human plasma by high-performance liquid chromatography without prior derivatization.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118

• Valproic acid monotherapy induces DNA oxidative damage.

  Toxicology 20060116

• Fetal exposure to sodium valproate associated with Baller-Gerold syndrome: case report and review of the literature.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20060101

• Environmental enrichment reverses behavioral alterations in rats prenatally exposed to valproic acid: issues for a therapeutic approach in autism.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060101

• Toxic epidermal necrolysis with combination lamotrigine and valproate in bipolar disorder.

  Progress in neuro-psychopharmacology & biological psychiatry 20060101

• The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia.

  Cancer 20060101

• Histone deacetylase inhibition by valproic acid down-regulates c-FLIP/CASH and sensitizes hepatoma cells towards CD95- and TRAIL receptor-mediated apoptosis and chemotherapy.

  Oncology reports 20060101

• Acquired factor V inhibitor associated with valproic acid use in a cirrhotic patient.

  Gut 20060101

• Valproic acid selectively inhibits conversion of arachidonic acid to arachidonoyl-CoA by brain microsomal long-chain fatty acyl-CoA synthetases: relevance to bipolar disorder.

  Psychopharmacology 20060101

• Possible interaction between lopinavir/ritonavir and valproic Acid exacerbates bipolar disorder.

  The Annals of pharmacotherapy 20060101

• Bioequivalence in development of antiepileptic drugs.

  Epilepsy research 20060101

• Adjunctive lamotrigine as a possible mania inducer in bipolar patients.

  The American journal of psychiatry 20060101

• Adjunct divalproex or lithium to clozapine in treatment-resistant schizophrenia.

  The Psychiatric quarterly 20060101

• Epigastric pain.

  The Journal of emergency medicine 20060101

• Parkinsonism and/or cognitive impairment with valproic acid therapy: a report of ten cases.

  Pharmacopsychiatry 20060101

• Valproic acid in epilepsy : pregnancy-related issues.

  Drug safety 20060101

• Dose-dependent improvement of myoclonic hyperkinesia due to Valproic acid in eight Huntington's Disease patients: a case series.

  BMC neurology 20060101

• Use of intravenous valproate in a patient with neuroleptic malignant syndrome.

  The Journal of neuropsychiatry and clinical neurosciences 20060101

• [Pancreatitis coincident with valproate and olanzapine use].

  Neurologia (Barcelona, Spain) 20060101

• The common inositol-reversible effect of mood stabilizers on neurons does not involve GSK3 inhibition, myo-inositol-1-phosphate synthase or the sodium-dependent myo-inositol transporters.

  Molecular and cellular neurosciences 20060101

• [Pharmacokinetic interaction between valproic acid and meropenem].

  Anales de pediatria (Barcelona, Spain : 2003) 20060101

• Development of water-phase derivatization followed by solid-phase microextraction and gas chromatography/mass spectrometry for fast determination of valproic acid in human plasma.

  Rapid communications in mass spectrometry : RCM 20060101

• Evolution of serum lipids and lipoprotein (a) levels in epileptic children treated with carbamazepine, valproic acid, and phenobarbital.

  Journal of child neurology 20060101

• Effect of antiepileptic drugs on plasma lipids, lipoprotein (a), and liver enzymes.

  Journal of child neurology 20060101

• An integrated study of acute effects of valproic acid in the liver using metabonomics, proteomics, and transcriptomics platforms.

  Omics : a journal of integrative biology 20060101

• Valproate as a mainstay of therapy for pediatric epilepsy.

  Paediatric drugs 20060101

• Treatment with valproic acid, all-trans retinoic acid (ATRA) and theophyllamine for 9 days caused a persistent increase in peripheral blood platelet counts for a patient with acute myelogenous leukemia.

  Acta oncologica (Stockholm, Sweden) 20060101

• Delta-sleep-inducing peptide potentiates anticonvulsive activity of valproate against metaphit-provoked audiogenic seizure in rats.

  Pharmacology 20060101

• Valproic acid and risk of acute pancreatitis: a population-based case-control study.

  American journal of therapeutics 20060101

• Prolonged use of phenytoin, carbamazepine or valproate monotherapy on plasma levels of folate and B(12): a comparison between epileptic patients with or without cardiovascular disorders.

  Neuro endocrinology letters 20060101

• Drug rash with eosinophilia and systemic symptoms induced by valproate and carbamazepine: formation of circulating auto-antibody against 190-kDa antigen.

  Acta dermato-venereologica 20060101

• Pharmacological intervention for cognitive deficits and aggression in frontal lobe injury.

  NeuroRehabilitation 20060101

• Polycystic ovary syndrome: the influence of environmental and genetic factors.

  Hormones (Athens, Greece) 20060101

• A retrospective analysis of changing from alternative agents to carbamazepine extended-release capsules in bipolar disorder.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20060101

• [Investigation of efficacy of convulex-retard in epilepsy treatment].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

• Pharmacokinetic parameters of total and unbound valproic acid and their relationships to seizure control in epileptic children.

  American journal of therapeutics 20060101

• Role of valproate across the ages. Treatment of epilepsy in children.

  Acta neurologica Scandinavica. Supplementum 20060101

• Role of valproate across the ages. Treatment of epilepsy in adults.

  Acta neurologica Scandinavica. Supplementum 20060101

• Role of valproate across the ages. Treatment of epilepsy in the elderly.

  Acta neurologica Scandinavica. Supplementum 20060101

• [Monitoring serum valproic acid concentration in hypoalbuminemic patients].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101

• Autistic epileptiform regression.

  Functional neurology 20060101

• Abdominal migraine and treatment with intravenous valproic Acid.

  Psychosomatics 20060101

• Modulation of serum concentrations of melatonin by carbamazepine and valproate.

  Indian journal of physiology and pharmacology 20060101

• [Necessity of novel single-antipsychotic-agent therapies for acute phase of schizophrenia].

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20060101

• Valproate, thalidomide and ethyl alcohol alter the migration of HTR-8/SVneo cells.

  Reproductive biology and endocrinology : RB&E 20060101

• Neuroleptic malignant syndrome and serotonin syndrome in the critical care setting: case analysis.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20060101

• Efficacy profiles of psychopharmacology: divalproex sodium in conduct disorder.

  Child psychiatry and human development 20060101

• Fractures in children with cerebral palsy.

  Journal of pediatric orthopedics 20060101

• [Asymptomatic carnitine depletion on ketogenic diet in patients with pharmacoresistant epilepsies].

  Klinische Padiatrie 20060101

• Reversible cerebral atrophy: a case report and literature review.

  General hospital psychiatry 20060101

• The role of continuous renal replacement therapy in the treatment of poisoning.

  Seminars in dialysis 20060101

• Induction of the homeotic gene Hoxa1 through valproic acid's teratogenic mechanism of action.

  Neurotoxicology and teratology 20060101

• Treatment of rapid-cycling bipolar disorder.

  The Journal of clinical psychiatry 20060101

• Effect of sodium valproate monotherapy on serum uric acid concentrations in ambulatory epileptic children: a prospective long-term study.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20060101

• Juvenile myoclonic epilepsy: epidemiology, pathophysiology, and management.

  Paediatric drugs 20060101

• The management of refractory status epilepticus: an update.

  Epilepsia 20060101

• Effects of sodium valproate on renal functions in rats.

  Renal failure 20060101

• [Sodium valproate as a cause of acute pancreatitis: a case report].

  Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru 20060101

• Bipolar depression: diagnostic and treatment considerations.

  Development and psychopathology 20060101

• Induction of a mixed depressive episode during rTMS treatment in a patient with refractory major depression.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20060101

• Acute exposure to caffeine decreases the anticonvulsant action of ethosuximide, but not that of clonazepam, phenobarbital and valproate against pentetrazole-induced seizures in mice.

  Pharmacological reports : PR 20060101

• Therapeutic monitoring of valproate in psychiatry: how far have we progressed?

  Clinical neuropharmacology 20060101

• Treatment of polydrug-using opiate dependents during withdrawal: towards a standardisation of treatment.

  BMC psychiatry 20060101

• Divalproex sodium for the treatment of behavioural problems associated with dementia in the elderly.

  Drugs & aging 20060101

• Oxidative stress as a mechanism of valproic acid-associated hepatotoxicity.

  Drug metabolism reviews 20060101

• Valproic acid is associated with cognitive decline in HIV-infected individuals: a clinical observational study.

  BMC neurology 20060101

• Valproic acid and butyrate induce apoptosis in human cancer cells through inhibition of gene expression of Akt/protein kinase B.

  Molecular cancer 20060101

• Efficacy and tolerability of divalproex extended release in psychiatric patients.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20060101

• Empirical evidence for the use of lithium and anticonvulsants in children with psychiatric disorders.

  Harvard review of psychiatry 20060101

• Pharmacokinetic interaction between valproic acid and ertapenem.

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101

• [Pharmacokinetic interaction between valproic acid and imipenem].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101

• Epigenetic targets in GABAergic neurons to treat schizophrenia.

  Advances in pharmacology (San Diego, Calif.) 20060101

• A proof-of-principle study of epigenetic therapy added to neoadjuvant doxorubicin cyclophosphamide for locally advanced breast cancer.

  PloS one 20060101

• [Anticonvulsants treatment of psychiatric disorder in elderly patients].

  Przeglad lekarski 20060101

• [Lance-Adams syndrome in patient with anoxic encephalopathy in the course of bronchial asthma].

  Wiadomosci lekarskie (Warsaw, Poland : 1960) 20060101

• Treatment of status epilepticus in adults: guidelines of the Italian League against Epilepsy.

  Epilepsia 20060101

• [The use of sulbuthiamine (enerion) in the combined therapy of patients with symptomatic focal epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20060101

• Functional half-life is a meaningful descriptor of steady-state pharmacokinetics of an extended-release formulation of a rapidly cleared drug : as shown by once-daily divalproex-ER.

  Clinical drug investigation 20060101

• Manic switch and serotonin syndrome with venlafaxine-lithium-valproate association.

  Therapie 20060101

• [Hyponatremia induced by sodium valproate. A case report].

  Therapie 20060101

• [Long latency auditory evoked potentials in schoolchildren and adolescents with epilepsy].

  Przeglad lekarski 20060101

• Interfering with the dynamics of estrogen receptor-regulated transcription.

  Ernst Schering Foundation symposium proceedings 20060101

• The epigenetic modifier, valproic acid, enhances radiation sensitivity.

  Epigenetics 20060101

• Genetic perturbation of glycolysis results in inhibition of de novo inositol biosynthesis.

  The Journal of biological chemistry 20051223

• Valproic acid-mediated Hsp70 induction and anti-apoptotic neuroprotection in SH-SY5Y cells.

  FEBS letters 20051219

• Valproate is an anti-androgen and anti-progestin.

  Steroids 20051215

• Clinical trial of valproic acid and all-trans retinoic acid in patients with poor-risk acute myeloid leukemia.

  Cancer 20051215

• Leptin, ghrelin, and adiponectin in epileptic patients treated with valproic acid.

  Neurology 20051213

• Case records of the Massachusetts General Hospital. Case 37-2005. A 35-year-old man with cardiac arrest while sleeping.

  The New England journal of medicine 20051208

• Short chain fatty acids regulate tyrosine hydroxylase gene expression through a cAMP-dependent signaling pathway.

  Brain research. Molecular brain research 20051207

• Valproate attenuates dextroamphetamine-induced subjective changes more than lithium.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20051201

• Lithium- and valproate-induced alterations in circadian locomotor behavior in Drosophila.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051201

• Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells.

  Biological psychiatry 20051201

• Efficacy of antiepileptic tetramethylcyclopropyl analogues of valproic acid amides in a rat model of neuropathic pain.

  Neuropharmacology 20051201

• An investigation of the efficacy of mood stabilizers in rodent models of prepulse inhibition.

  The Journal of pharmacology and experimental therapeutics 20051201

• Hepatocellular carcinoma and nonalcoholic steatohepatitis developing during long-term administration of valproic acid.

  Virchows Archiv : an international journal of pathology 20051201

• Pharmacodynamic and/or pharmacokinetic characteristics of interactions between loreclezole and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice: an isobolographic analysis.

  Epilepsy & behavior : E&B 20051201

• Longitudinal evaluation of reproductive function in women treated for bipolar disorder.

  Journal of affective disorders 20051201

• The use of Monte Carlo simulations to study the effect of poor compliance on the steady state concentrations of valproic acid following administration of enteric-coated and extended release divalproex sodium formulations.

  Biopharmaceutics & drug disposition 20051201

• Rapid versus non-rapid cycling as a predictor of response to olanzapine and divalproex sodium for bipolar mania and maintenance of remission: post hoc analyses of 47-week data.

  Journal of affective disorders 20051201

• Use of phenytoin and other anticonvulsant prophylaxis in patients with aneurysmal subarachnoid hemorrhage.

  Stroke 20051201

• Results of a phase 2 study of valproic acid alone or in combination with all-trans retinoic acid in 75 patients with myelodysplastic syndrome and relapsed or refractory acute myeloid leukemia.

  Annals of hematology 20051201

• Clinical experience with decitabine in North American patients with myelodysplastic syndrome.

  Annals of hematology 20051201

• The LAM-SAFE Study: lamotrigine versus carbamazepine or valproic acid in newly diagnosed focal and generalised epilepsies in adolescents and adults.

  Seizure 20051201

• Acute hyperammonemic coma with chronic valproic acid therapy.

  The Annals of pharmacotherapy 20051201

• Histone deacetylase inhibitors promote osteoblast maturation.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051201

• Interstitial pneumonitis during lamotrigine therapy.

  British journal of clinical pharmacology 20051201

• Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells.

  Journal of neurochemistry 20051201

• Cost-effectiveness of clinical interventions for reducing the global burden of bipolar disorder.

  The British journal of psychiatry : the journal of mental science 20051201

• Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20051201

• Ictal video-polysomnography and EEG spectral analysis in a child with severe Panayiotopoulos syndrome.

  Epileptic disorders : international epilepsy journal with videotape 20051201

• Suicidal ideation and pharmacotherapy among STEP-BD patients.

  Psychiatric services (Washington, D.C.) 20051201

• [Treatment with valproate and hepatic steatosis].

  Revista de neurologia 20051201

• Exencephaly induction by valproic acid in the genetic polydactyly/arhinencephaly mouse, Pdn/Pdn.

  Congenital anomalies 20051201

• Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells.

  Surgery 20051201

• Valproic acid induces growth arrest, apoptosis, and senescence in medulloblastomas by increasing histone hyperacetylation and regulating expression of p21Cip1, CDK4, and CMYC.

  Molecular cancer therapeutics 20051201

• In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates.

  Molecular cancer therapeutics 20051201

• A randomized, double-blind, placebo-controlled pilot trial of safety and tolerability of two doses of divalproex sodium in outpatients with probable Alzheimer's disease.

  Current Alzheimer research 20051201

• Macrocytosis associated with divalproex treatment.

  Journal of child and adolescent psychopharmacology 20051201

• ACTH responses to somatostatin, valproic acid and dexamethasone in Nelson's syndrome.

  Neuro endocrinology letters 20051201

• Management of epilepsy in adults. Diagnosis guidelines.

  Postgraduate medicine 20051201

• New research finds possible treatment for latent HIV. Valproic acid used to deplete HIV.

  AIDS alert 20051201

• Baseline predictors of response to divalproex in conduct disorder.

  The Journal of clinical psychiatry 20051201

• Omega-3 fatty acids are more beneficial in the depressive phase than in the manic phase in patients with bipolar I disorder.

  The Journal of clinical psychiatry 20051201

• Clonidine-induced gynecomastia and hyperprolactinemia in a 6-year-old child.

  The Journal of clinical psychiatry 20051201

• Severe impulsiveness as the primary manifestation of multiple sclerosis in a young female.

  Psychiatry and clinical neurosciences 20051201

• [Antineoplastic effect of valproic acid and trichostatin on HL-60 and K562 cells].

  Zhongguo shi yan xue ye xue za zhi 20051201

• [Experimental study on the mechanism of the apoptosis of leukemic cells induced by valproic acid].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20051201

• Managing adverse reactions to psychotropic medications.

  Pediatric annals 20051201

• Immunogold study of effects of prenatal exposure to lipopolysaccharide and/or valproic acid on the rat blood-brain barrier vessels.

  Journal of neurocytology 20051201

• Increase in Ara-C cytotoxicity in the presence of valproate, a histone deacetylase inhibitor, is associated with the concurrent expression of cyclin D1 and p27(Kip 1) in acute myeloblastic leukemia cells.

  Leukemia research 20051101

• Influence of sodium valproate on sodium and chloride urinary excretion in rats, gender differences.

  Pharmacology 20051101

• Treatment with valproic acid for myelofibrosis with myeloid metaplasia.

  Annals of hematology 20051101

• Sodium valproate inhibits glucose transport and exacerbates Glut1-deficiency in vitro.

  Journal of cellular biochemistry 20051101

• Valproic acid reduces enhanced vesicular glutamate transporter immunoreactivities in the dentate gyrus of the seizure prone gerbil.

  Neuropharmacology 20051101

• Impulsive aggression with irritability and responsive to divalproex: a pediatric bipolar spectrum disorder phenotype?

  Journal of affective disorders 20051101

• Effect of valproate on plasma levels of interleukin-6 in healthy male humans.

  International clinical psychopharmacology 20051101

• Prolonged postictal stupor: nonconvulsive status epilepticus, medication effect, or postictal state?

  Epilepsy & behavior : E&B 20051101

• Levetiracetam for mood stabilization and maintenance of seizure control following multiple treatment failures.

  The Annals of pharmacotherapy 20051101

• Valproic acid-induced skeletal malformations: associated gene expression cascades.

  Pharmacogenetics and genomics 20051101

• In Saccharomyces cerevisiae, impaired PRPP synthesis is accompanied by valproate and Li+ sensitivity.

  Biochemical Society transactions 20051101

• Efficiency of the Genius batch hemodialysis system with low serum solute concentrations: the case of lithium intoxication therapy.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20051101

• A 20-month, double-blind, maintenance trial of lithium versus divalproex in rapid-cycling bipolar disorder.

  The American journal of psychiatry 20051101

• Conclusions inconsistent with results with amphetamines and divalproex.

  The American journal of psychiatry 20051101

• [Valproate sustained release in the treatment of epilepsy].

  Fortschritte der Neurologie-Psychiatrie 20051101

• Divalproex sodium in nursing home residents with possible or probable Alzheimer Disease complicated by agitation: a randomized, controlled trial.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20051101

• Clozapine-induced pericarditis, pericardial tamponade, polyserositis, and rash.

  The Journal of clinical psychiatry 20051101

• Chrono impact versus enteric coated valproate in Thai epileptic patients.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20051101

• Targeting epigenetic changes in acute myeloid leukemia.

  Clinical advances in hematology & oncology : H&O 20051101

• Drug-induced weight gain.

  Timely topics in medicine. Cardiovascular diseases 20051028

• Apoptosis-associated tyrosine kinase (AATYK) has differential Ca2+-dependent phosphorylation states in response to survival and apoptotic conditions in cerebellar granule cells.

  The Journal of biological chemistry 20051021

• Catalytic mechanism of limonene epoxide hydrolase, a theoretical study.

  Journal of the American Chemical Society 20051019

• Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.

  The Cochrane database of systematic reviews 20051019

• Worsening of psychotic symptoms in schizophrenia with addition of lamotrigine: a case report.

  Schizophrenia research 20051015

• Induction of osteogenic differentiation of human mesenchymal stem cells by histone deacetylase inhibitors.

  Journal of cellular biochemistry 20051015

• Severe hypothermia in association with sodium valproate overdose.

  The New Zealand medical journal 20051007

• [Valproate-caused encephalopathy].

  Ugeskrift for laeger 20051003

• Relationship of mania symptomatology to maintenance treatment response with divalproex, lithium, or placebo.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20051001

• Chronic valproate does not alter the kinetics of docosahexaenoic acid within brain phospholipids of the unanesthetized rat.

  Psychopharmacology 20051001

• [Migraine therapy].

  Der Internist 20051001

• Patient characteristics and treatment implications of marijuana abuse among bipolar alcoholics: results from a double blind, placebo-controlled study.

  Addictive behaviors 20051001

• [Acceptability and tolerance of sodium valproate, a new sustained-action granule formulation, in monotherapy for epileptic children from 3 years old].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20051001

• Histone deacetylases in acute myeloid leukaemia show a distinctive pattern of expression that changes selectively in response to deacetylase inhibitors.

  Leukemia 20051001

• The efficacy of divalproex sodium in the treatment of agitation associated with major depression.

  Journal of clinical psychopharmacology 20051001

• Prophylactic effect of valproate in the treatment for siblings with catatonia: a case report.

  Journal of clinical psychopharmacology 20051001

• Valproate: a simple chemical with so much to offer.

  Journal of clinical pharmacy and therapeutics 20051001

• Inhibition of histone deacetylase activity on specific embryonic tissues as a new mechanism for teratogenicity.

  Birth defects research. Part B, Developmental and reproductive toxicology 20051001

• [Effect of carbamazepine and valproate on bone metabolism in children with epilepsy].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20051001

• The use of lamotrigine and other antiepileptic drugs in paediatric patients at a Malaysian hospital.

  Pharmacy world & science : PWS 20051001

• Valproate-induced insulin resistance in prepubertal girls with epilepsy.

  Journal of pediatric endocrinology & metabolism : JPEM 20051001

• Serum insulin, leptin, and neuropeptide y levels in epileptic children treated with valproate.

  Journal of child neurology 20051001

• Fatal seizures due to potential herb-drug interactions with Ginkgo biloba.

  Journal of analytical toxicology 20051001

• [Successful treatment with cyclosporine of sodium valproate-induced pure red cell aplasia].

  [Rinsho ketsueki] The Japanese journal of clinical hematology 20051001

• Lamotrigine associated with exacerbation or de novo myoclonus in idiopathic generalized epilepsies.

  Neurology 20050913

• Influence of ethanol on the threshold for electroshock-induced seizures and electrically-evoked hippocampal afterdischarges.

  Journal of neural transmission (Vienna, Austria : 1996) 20050901

• Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylenetetrazol-induced kindling in mice.

  Neuropharmacology 20050901

• Visual function in epilepsy patients treated with initial valproate monotherapy.

  Seizure 20050901

• Efficacy of antiepileptic isomers of valproic acid and valpromide in a rat model of neuropathic pain.

  British journal of pharmacology 20050901

• Prolonged molecular remission in PML-RARalpha-positive acute promyelocytic leukemia treated with minimal chemotherapy followed by maintenance including the histone deacetylase inhibitor sodium valproate.

  Leukemia 20050901

• Once-a-day extended-release dosage form of divalproex sodium III: development and validation of a Level A in vitro-in vivo correlation (IVIVC).

  Journal of pharmaceutical sciences 20050901

• Maternal valproate dosage and foetal malformations.

  Acta neurologica Scandinavica 20050901

• Effect of divalproex on metabolic parameters is dose related in migraine prophylaxis.

  Headache 20050901

• Nonconvulsive status epilepticus: clinical features and diagnostic challenges.

  The Psychiatric clinics of North America 20050901

• Increased replication of human cytomegalovirus in retinal pigment epithelial cells by valproic acid depends on histone deacetylase inhibition.

  Investigative ophthalmology & visual science 20050901

• Cingulate cortex anatomical abnormalities in children and adolescents with bipolar disorder.

  The American journal of psychiatry 20050901

• Drowsiness and disorientation in a woman with depression.

  Journal of the American Geriatrics Society 20050901

• [The risk of defects in the neural tube caused by valproic acid and carbamazepine].

  Revista de neurologia 20050901

• Interactive case conference. First episode: depression and panic disorder.

  CNS spectrums 20050901

• Preclinical profiling and safety studies of ABT-769: a compound with potential for broad-spectrum antiepileptic activity.

  Epilepsia 20050901

• Pregabalin drug interaction studies: lack of effect on the pharmacokinetics of carbamazepine, phenytoin, lamotrigine, and valproate in patients with partial epilepsy.

  Epilepsia 20050901

• Safety and tolerability of the ketogenic diet in pediatric epilepsy: effects of valproate combination therapy.

  Epilepsia 20050901

• What do insulin, estrogen, valproic acid, and TDZD-8 have in common?

  Critical care medicine 20050901

• Pharmacokinetic interaction between valproic acid and meropenem.

  Intensive care medicine 20050901

• Valproate-induced encephalopathy.

  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20050901

• Valproate and HDAC inhibition: a new epigenetic strategy to mitigate phenotypic severity in ALS?

  Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20050901

• Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up.

  The journal of headache and pain 20050901

• Targeting HIV reservoirs with valproic acid.

  The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20050901

• Fit for a fracture.

  The Medical journal of Australia 20050815

• Depletion of latent HIV-1 infection in vivo: a proof-of-concept study.

  Lancet (London, England) 20050813

• HIV/AIDS. Report of novel treatment aimed at latent HIV raises the 'c word'.

  Science (New York, N.Y.) 20050812

• Pooling samples within microarray studies: a comparative analysis of rat liver transcription response to prototypical toxicants.

  Physiological genomics 20050811

• Efficacy of rapid IV administration of valproic acid for status epilepticus.

  Neurology 20050809

• Histone deacetylase activity and COPD.

  The New England journal of medicine 20050804

• Valproic acid potentiates both typical and atypical antipsychotic-induced prefrontal cortical dopamine release.

  Brain research 20050802

• Valproic acid II: effects on oxidative stress, mitochondrial membrane potential, and cytotoxicity in glutathione-depleted rat hepatocytes.

  Toxicological sciences : an official journal of the Society of Toxicology 20050801

• Valproic acid I: time course of lipid peroxidation biomarkers, liver toxicity, and valproic acid metabolite levels in rats.

  Toxicological sciences : an official journal of the Society of Toxicology 20050801

• Increased erythrocyte distribution of valproic acid in pharmacokinetic interaction with carbapenem antibiotics in rat and human.

  Journal of pharmaceutical sciences 20050801

• Acute valproate poisoning: pharmacokinetics, alteration in fatty acid metabolism, and changes during therapy.

  Journal of clinical psychopharmacology 20050801

• Hemispheric integrative therapy in Landau-Kleffner syndrome: applications for rehabilitation sciences.

  The International journal of neuroscience 20050801

• Analysis of pregabalin at therapeutic concentrations in human plasma/serum by reversed-phase HPLC.

  Therapeutic drug monitoring 20050801

• Outcome measurement, outcome management and monitoring.

  The Australian and New Zealand journal of psychiatry 20050801

• Extended-release divalproex sodium for patients with side effects from delayed-release divalproex sodium.

  The American journal of psychiatry 20050801

• Valproic acid: a potential role in treating latent HIV infection.

  Lancet (London, England) 20050801

• Differential effects of chronic lithium and valproate on brain activation in healthy volunteers.

  Human psychopharmacology 20050801

• Migraine--diagnosis and treatment.

  Australian family physician 20050801

• Weight change in monozygotic twins treated with valproate.

  Obesity research 20050801

• Valproate-induced bleeding: report of two cases and review of literature.

  Indian pediatrics 20050801

• Phenytoin stimulates chondrogenic differentiation in mouse clonal chondrogenic EC cells, ATDC5.

  The Journal of toxicological sciences 20050801

• The antiapoptotic actions of mood stabilizers: molecular mechanisms and therapeutic potentials.

  Annals of the New York Academy of Sciences 20050801

• A double-blind, placebo-controlled study of valproate for aggression in youth with pervasive developmental disorders.

  Journal of child and adolescent psychopharmacology 20050801

• Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A.

  Oncogene 20050721

• Natural killer cell-mediated lysis of hepatoma cells via specific induction of NKG2D ligands by the histone deacetylase inhibitor sodium valproate.

  Cancer research 20050715

• Aminoglutethimide but not spironolactone enhances the anticonvulsant effect of some antiepileptics against amygdala-kindled seizures in rats.

  Journal of neural transmission (Vienna, Austria : 1996) 20050701

• Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies.

  Medicinal research reviews 20050701

• Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050701

• Modulation of peroxisome proliferator-activated receptor delta activity affects neural cell adhesion molecule and polysialyltransferase ST8SiaIV induction by teratogenic valproic acid analogs in F9 cell differentiation.

  Molecular pharmacology 20050701

• Effect of sodium valproate on nocturnal melatonin sensitivity to light in healthy volunteers.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050701

• Increase in platelet count in older, poor-risk patients with acute myeloid leukemia or myelodysplastic syndrome treated with valproic acid and all-trans retinoic acid.

  Cancer 20050701

• Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701

• The histone deacetylase inhibitor valproic acid alters sensitivity towards all trans retinoic acid in acute myeloblastic leukemia cells.

  Leukemia 20050701

• Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid.

  Leukemia research 20050701

• Neuroleptic malignant syndrome due to three atypical antipsychotics in a child.

  Journal of psychopharmacology (Oxford, England) 20050701

• Lamotrigine add-on to valproate therapy for paediatric bipolar affective disorder.

  The Australian and New Zealand journal of psychiatry 20050701

• Valproic acid and all-trans retinoic acid for the treatment of elderly patients with acute myeloid leukemia.

  Haematologica 20050701

• A comparative study of the effect of carbamazepine and valproic acid on the pharmacokinetics and metabolic profile of topiramate at steady state in patients with epilepsy.

  Epilepsia 20050701

• Children exposed to valproate in utero--population based evaluation of risks and confounding factors for long-term neurocognitive development.

  Epilepsy research 20050701

• Lithium and valproic acid treatments reduce PKC activation and receptor-G protein coupling in platelets of bipolar manic patients.

  Journal of psychiatric research 20050701

• Bipolar depression.

  CNS spectrums 20050701

• Protective effects of valproic acid against hypoxic-ischemic brain injury in neonatal rats.

  Journal of child neurology 20050701

• [A new target of cancer therapy: advances in the study of histone deacetylase].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050701

• [Are mood stabilizers beneficial in the treatment of schizophrenia?].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050630

• Antiepileptic drug use of women with epilepsy and congenital malformations in offspring.

  Neurology 20050614

• Different effects of valproate on methamphetamine- and cocaine-induced behavioral sensitization in mice.

  Behavioural brain research 20050603

• Secondary renal Fanconi syndrome caused by valproate therapy.

  Pediatric nephrology (Berlin, Germany) 20050601

• p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells.

  Oncology reports 20050601

• Valproic acid glucuronidation is associated with increases in 15-F2t-isoprostane in rats.

  Free radical biology & medicine 20050601

• Reproductive function and risk for PCOS in women treated for bipolar disorder.

  Bipolar disorders 20050601

• GSK-3 activity in neocortical cells is inhibited by lithium but not carbamazepine or valproic acid.

  Bipolar disorders 20050601

• Divalproex sodium for pediatric mixed mania: a 6-month prospective trial.

  Bipolar disorders 20050601

• A psychotic episode associated with the Atkins diet in a patient with bipolar disorder.

  Bipolar disorders 20050601

• Valproic acid binding to human serum and human placenta in vitro.

  Therapeutic drug monitoring 20050601

• How can the mood stabilizer VPA limit both mania and depression?

  Molecular and cellular neurosciences 20050601

• High vulnerability to acute dystonic reactions: a case of antipsychotic exposure and uncontrolled seizure activity.

  Progress in neuro-psychopharmacology & biological psychiatry 20050601

• Motor impairment on awakening in a patient with an EEG pattern of 'unilateral, continuous spikes and waves during slow sleep'.

  Epileptic disorders : international epilepsy journal with videotape 20050601

• Treatment of valproate-induced hyperammonemia.

  Journal of the American Geriatrics Society 20050601

• Effectiveness and medical costs of divalproex versus lithium in the treatment of bipolar disorder: results of a naturalistic clinical trial.

  Journal of affective disorders 20050601

• Potential risks associated with high-dose valproate in pregnancy in psychiatric patients.

  The Australian and New Zealand journal of psychiatry 20050601

• Successful initiation of combined therapy with valproate sodium injection and divalproex sodium extended-release tablets in the epilepsy monitoring unit.

  Epilepsia 20050601

• Serum valproate levels with oral contraceptive use.

  Epilepsia 20050601

• Bending the rule of monotherapy for migraine prevention?

  Headache 20050601

• Reduced anticonvulsant efficacy of valproic acid in dopamine beta-hydroxylase knockout mice.

  Epilepsy research 20050601

• A case of delirium and subsequent pancytopenia associated with the oral loading of valproic acid.

  The Journal of clinical psychiatry 20050601

• Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers.

  Clinical pharmacology and therapeutics 20050601

• Lethal obesity associated with sodium valproate in a brain-injured patient.

  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20050601

• Valproate-induced hyperammonemic encephalopathy with normal liver function.

  Neurology India 20050601

• Split-hand/split-foot malformation associated with maternal valproate consumption.

  Neurology India 20050601

• Anticonvulsant drug therapies.

  Journal of psychosocial nursing and mental health services 20050601

• Effectiveness of lamotrigine in clinical practice: results of a retrospective population-based study.

  Epilepsy research 20050601

• Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report.

  International psychogeriatrics 20050601

• [Hyperammonemia secondary to the use of valproic acid: case report].

  Arquivos de neuro-psiquiatria 20050601

• Absence seizures in children.

  Clinical evidence 20050601

• Bipolar disorder.

  Clinical evidence 20050601

• Investigating heterogeneity in an individual patient data meta-analysis of time to event outcomes.

  Statistics in medicine 20050515

• The targeting of primary effusion lymphoma cells for apoptosis by inducing lytic replication of human herpesvirus 8 while blocking virus production.

  Blood 20050515

• Histone deacetylases inhibition and tumor cells cytotoxicity by CNS-active VPA constitutional isomers and derivatives.

  Biochemical pharmacology 20050515

• Carbamazepine is an inhibitor of histone deacetylases.

  Life sciences 20050513

• Class II (IIa)-selective histone deacetylase inhibitors. 1. Synthesis and biological evaluation of novel (aryloxopropenyl)pyrrolyl hydroxyamides.

  Journal of medicinal chemistry 20050505

• The anti-apoptotic, glucocorticoid receptor cochaperone protein BAG-1 is a long-term target for the actions of mood stabilizers.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050504

• Hyperprolinemia is a risk factor for schizoaffective disorder.

  Molecular psychiatry 20050501

• Characteristics of glutamine metabolism in human precision-cut kidney slices: a 13C-NMR study.

  The Biochemical journal 20050501

• Effects of valproic acid derivatives on inositol trisphosphate depletion, teratogenicity, glycogen synthase kinase-3beta inhibition, and viral replication: a screening approach for new bipolar disorder drugs derived from the valproic acid core structure.

  Molecular pharmacology 20050501

• Beneficial interaction between vigabatrin and valproate against seizures induced by pentylenetetrazole in mice.

  Pharmacological research 20050501

• The role of histone acetylation in SMN gene expression.

  Human molecular genetics 20050501

• Pharmacological outcomes in newly diagnosed epilepsy.

  Epilepsy & behavior : E&B 20050501

• Pharmacokinetic interaction on valproic acid and recurrence of epileptic seizures during chemotherapy in an epileptic patient.

  British journal of clinical pharmacology 20050501

• Double-blind 18-month trial of lithium versus divalproex maintenance treatment in pediatric bipolar disorder.

  Journal of the American Academy of Child and Adolescent Psychiatry 20050501

• Inhibition of persistent sodium current fraction and voltage-gated L-type calcium current by propofol in cortical neurons: implications for its antiepileptic activity.

  Epilepsia 20050501

• NICE recommendations for valproate treatment are unhelpful.

  The British journal of psychiatry : the journal of mental science 20050501

• Anticonvulsant hypersensitivity syndrome from addition of lamotrigine to divalproex.

  The American journal of psychiatry 20050501

• Valproic acid alters chromatin structure by regulation of chromatin modulation proteins.

  Cancer research 20050501

• Management of epilepsy in women.

  Postgraduate medical journal 20050501

• Anticonvulsant medications for migraine prevention.

  American family physician 20050501

• L-carnitine was safely administered in the setting of valproate toxicity.

  The American journal of emergency medicine 20050501

• Endocrine and metabolic changes in epileptic patients receiving valproic acid.

  Journal of pediatric endocrinology & metabolism : JPEM 20050501

• Blood homocysteine, folate and vitamin B-12 concentrations in patients with epilepsy receiving lamotrigine or sodium valproate for initial monotherapy.

  Epilepsy research 20050501

• [Successful balloon-occluded retrograde transvenous obliteration (B-RTO) in a case of symptomatic epilepsy with hepatic encephalopathy due to non-cirrhotic porto-systemic shunt].

  Rinsho shinkeigaku = Clinical neurology 20050501

• Seizure worsening caused by decreased serum valproate during meropenem therapy.

  Journal of child neurology 20050501

• Carnitine levels in valproic acid-treated psychiatric patients: a cross-sectional study.

  The Journal of clinical psychiatry 20050501

• [Mexidol in treatment of children with generalized epilepsy and febrile seizures].

  Georgian medical news 20050501

• Microarray analysis of rat brain gene expression after chronic administration of sodium valproate.

  Brain research bulletin 20050430

• Valproic acid, but not lamotrigine, suppresses seizure-induced c-fos and c-Jun mRNA expression.

  Brain research. Molecular brain research 20050427

• Images in clinical medicine. Stevens-Johnson syndrome.

  The New England journal of medicine 20050421

• Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.

  Neurology 20050412

• Enhancement of in vitro and in vivo tumor cell radiosensitivity by valproic acid.

  International journal of cancer 20050410

• Valproic acid modulates NCAM polysialylation and polysialyltransferase mRNA expression in human tumor cells.

  International immunopharmacology 20050401

• Baller-Gerold syndrome after fetal exposure to sodium valproate.

  American journal of medical genetics. Part A 20050401

• Valproic acid enhances gene expression from viral gene transfer vectors.

  Journal of virological methods 20050401

• Divalproex in the treatment of bipolar depression: a placebo-controlled study.

  Journal of affective disorders 20050401

• Acute leukemia associated with valproic acid treatment: a novel mechanism for leukemogenesis?

  American journal of hematology 20050401

• Intravenous valproate as an innovative therapy in seizure emergency situations including status epilepticus--experience in 102 adult patients.

  Seizure 20050401

• Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice.

  Birth defects research. Part A, Clinical and molecular teratology 20050401

• Neurotoxicity associated with free valproic acid.

  The American journal of psychiatry 20050401

• Treatment of mania in children and adolescents.

  Current psychiatry reports 20050401

• Valproic acid stimulates proliferation and self-renewal of hematopoietic stem cells.

  Cancer research 20050401

• A transmission electron microscopic study of microglia/macrophages in the hippocampal cortex and neocortex following chronic exposure to valproate.

  International journal of experimental pathology 20050401

• Incidence of delirium in older adults newly prescribed lithium or valproate: a population-based cohort study.

  The Journal of clinical psychiatry 20050401

• Valproate-induced proximal renal tubular dysfunction: clinically relevant in the severely disabled epileptic population.

  Epilepsia 20050401

• Valproic acid-associated sialadenosis of the parotid and submandibular glands: diagnostic and therapeutic aspects.

  Acta oto-laryngologica 20050401

• Reduction of affective lability and alcohol use following traumatic brain injury: a clinical pilot study of anti-convulsant medications.

  Brain injury 20050401

• A theoretical method for normalizing total serum valproic acid concentration in hypoalbuminemic patients.

  Journal of pharmacological sciences 20050401

• New thyroxine treatment in older adults beginning lithium therapy: implications for clinical practice.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20050401

• Drug treatments for bipolar disorder: 1--Acute manic or depressive episodes.

  Drug and therapeutics bulletin 20050401

• Stiripentol: new preparation. Severe myoclonic epilepsy of infancy: promising.

  Prescrire international 20050401

• Novel anticonvulsants in the treatment of alcoholism.

  Expert opinion on investigational drugs 20050401

• Service utilization and costs of olanzapine versus divalproex treatment for acute mania: results from a randomized, 47-week clinical trial.

  Current medical research and opinion 20050401

• An experimental evaluation of anticonvulsant activity of Vitex-negundo.

  Indian journal of physiology and pharmacology 20050401

• Valproate pretreatment protects dopaminergic neurons from LPS-induced neurotoxicity in rat primary midbrain cultures: role of microglia.

  Brain research. Molecular brain research 20050324

• What can we say to women of reproductive age with epilepsy?

  Neurology 20050322

• Neuropsychological effects of exposure to anticonvulsant medication in utero.

  Neurology 20050322

• Increased rate of major malformations in offspring exposed to valproate during pregnancy.

  Neurology 20050322

• [Diminished antiepileptic drug serum levels during acyclovir treatment].

  Medicina clinica 20050312

• [Histone deacetylase inhibitors as a new generation of anti-cancer agents].

  Postepy higieny i medycyny doswiadczalnej (Online) 20050311

• Evaluation of the effects of lamotrigine, valproate and carbamazepine in a rodent model of mania.

  Behavioural brain research 20050307

• Valproic acid induces apoptosis and cell cycle arrest in poorly differentiated thyroid cancer cells.

  The Journal of clinical endocrinology and metabolism 20050301

• Valproate-induced parkinsonism: use of a newer pharmacovigilance tool to investigate the reporting of an unanticipated adverse event with an 'old' drug.

  Movement disorders : official journal of the Movement Disorder Society 20050301

• Lithium and valproate attenuate dextroamphetamine-induced changes in brain activation.

  Human psychopharmacology 20050301

• Valproate embryopathy: clinical and cognitive profile in 5 siblings.

  American journal of medical genetics. Part A 20050301

• Tiagabine as add-on therapy may be more effective with valproic acid--open label, multicentre study of patients with focal epilepsy.

  European journal of neurology 20050301

• A systematic review of treatment of typical absence seizures in children and adolescents with ethosuximide, sodium valproate or lamotrigine.

  Seizure 20050301

• Clozapine-induced stuttering, facial tics and myoclonic seizures: a case report.

  The Australian and New Zealand journal of psychiatry 20050301

• Co-existence of lycanthropy and Cotard's syndrome in a single case.

  Acta psychiatrica Scandinavica 20050301

• Acute seizures due to a probable interaction between valproic acid and meropenem.

  The Annals of pharmacotherapy 20050301

• Cognitive deterioration and electrical status epilepticus during slow sleep.

  Epilepsy & behavior : E&B 20050301

• Autoimmune haemolytic anaemia and renal Fanconi syndrome caused by valproate therapy.

  European journal of pediatrics 20050301

• Fatal cerebral edema after moderate valproic acid overdose.

  Annals of emergency medicine 20050301

• A placebo-controlled screening trial of olanzapine, valproate, and coenzyme Q10/L-carnitine for the treatment of cocaine dependence.

  Addiction (Abingdon, England) 20050301

• Extended-release divalproex in child and adolescent outpatients with epilepsy.

  Epilepsia 20050301

• Effects of anticonvulsants on human p450c17 (17alpha-hydroxylase/17,20 lyase) and 3beta-hydroxysteroid dehydrogenase type 2.

  Epilepsia 20050301

• Lamotrigine-induced rash--worth a rechallenge.

  Acta neurologica Scandinavica 20050301

• Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice.

  Biological psychiatry 20050301

• Impact of trait impulsivity and state aggression on divalproex versus placebo response in borderline personality disorder.

  The American journal of psychiatry 20050301

• Risperidone-associated transient diabetic ketoacidosis and diabetes mellitus type 1 in a patient treated with valproate and lithium.

  Pharmacopsychiatry 20050301

• Stevens-Johnson syndrome associated with single high dose of lamotrigine in a patient taking valproate.

  Dermatology online journal 20050301

• Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death.

  Neuropharmacology 20050301

• Valproic acid, in combination with all-trans retinoic acid and 5-aza-2'-deoxycytidine, restores expression of silenced RARbeta2 in breast cancer cells.

  Molecular cancer therapeutics 20050301

• Teratogenicity of sodium valproate.

  Expert opinion on drug safety 20050301

• Update on the treatment of bipolar disorder in children and adolescents.

  European psychiatry : the journal of the Association of European Psychiatrists 20050301

• New data on the use of lithium, divalproate, and lamotrigine in rapid cycling bipolar disorder.

  European psychiatry : the journal of the Association of European Psychiatrists 20050301

• Sodium valproate -- induced skeletal myopathy.

  Indian journal of pediatrics 20050301

• Improvement in tardive dyskinesia with aripiprazole use.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20050301

• [Evaluation of therapeutic project on acute tetramethylene disulphotetramine poisoning and effect on intelligence in children].

  Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20050301

• Divalproex sodium in the treatment of pediatric psychiatric disorders.

  Expert review of neurotherapeutics 20050301

• Effects of the histone deacetylase inhibitor valproic acid on Notch signalling in human neuroblastoma cells.

  British journal of cancer 20050227

• Histone deacetylase inhibitor valproic acid enhances the cytokine-induced expansion of human hematopoietic stem cells.

  Cancer research 20050215

• Valproate-induced alterations in human theca cell gene expression: clues to the association between valproate use and metabolic side effects.

  Physiological genomics 20050210

• Molecular studies probe bipolar disorder.

  JAMA 20050202

• Assessment of patient preference and side effects in patients switched from divalproex sodium delayed release to divalproex sodium extended release.

  Journal of clinical psychopharmacology 20050201

• A dosing algorithm for converting from valproate monotherapy to lamotrigine monotherapy in patients with epilepsy.

  Epilepsy & behavior : E&B 20050201

• Bipolar disorder and myo-inositol: a review of the magnetic resonance spectroscopy findings.

  Bipolar disorders 20050201

• Apoptosis on hepatoma cells but not on primary hepatocytes by histone deacetylase inhibitors valproate and ITF2357.

  Journal of hepatology 20050201

• Bone mass and turnover in women with epilepsy on antiepileptic drug monotherapy.

  Annals of neurology 20050201

• Lower effectiveness of divalproex versus valproic acid in a prospective, quasi-experimental clinical trial involving 9,260 psychiatric admissions.

  The American journal of psychiatry 20050201

• Computerized tremor analysis of valproate-induced tremor: a comparative study of controlled-release versus conventional valproate.

  Epilepsia 20050201

• Antiepileptic drugs alter reproductive endocrine hormones in men with epilepsy.

  European journal of neurology 20050201

• Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine.

  Biological psychiatry 20050201

• Mood stabilizer augmentation in apparently 'unipolar' MDD: predictors of response in the naturalistic French national EPIDEP study.

  Journal of affective disorders 20050201

• [Sjögren's syndrome with autonomic failure and epilepsy].

  La Revue de medecine interne 20050201

• Complex cardiac defect with hypoplastic right ventricle in a fetus with valproate exposure.

  Prenatal diagnosis 20050201

• Analysis of antiepileptic drugs in biological fluids by means of electrokinetic chromatography.

  Electrophoresis 20050201

• A comparison of anticonvulsants in the treatment of impulsive aggression.

  Experimental and clinical psychopharmacology 20050201

• Latest therapies for bipolar disorder. Looking beyond lithium.

  Postgraduate medicine 20050201

• Add-on melatonin improves sleep behavior in children with epilepsy: randomized, double-blind, placebo-controlled trial.

  Journal of child neurology 20050201

• Valproate-induced eosinophilia in children with epilepsy: role of interleukin-5.

  Journal of child neurology 20050201

• Topiramate-valproate-induced hyperammonemic encephalopathy syndrome: case report.

  Journal of child neurology 20050201

• Valproate-induced hyperammonemic encephalopathy.

  The Journal of the Association of Physicians of India 20050201

• Valproic acid induces apoptosis dependent of Yca1p at concentrations that mildly affect the proliferation of yeast.

  FEBS letters 20050131

• Efficacy of rapid IV administration of valproic acid for status epilepticus.

  Neurology 20050125

• Relations between substrate affinities and charge equilibration rates in the rat GABA cotransporter GAT1.

  The Journal of physiology 20050115

• Efficacy and tolerability of the new antiepileptic drugs I: treatment of new onset epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

  Neurology 20050111

• Behavioral alterations in rats prenatally exposed to valproic acid: animal model of autism.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050101

• Benign myoclonic epilepsy in infancy.

  Advances in neurology 20050101

• Lithium and bipolar mood disorder: the inositol-depletion hypothesis revisited.

  Molecular psychiatry 20050101

• Cancer risk in people with epilepsy: the role of antiepileptic drugs.

  Brain : a journal of neurology 20050101

• Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3.

  Journal of cell science 20050101

• Pharmacokinetics of aripiprazole and concomitant lithium and valproate.

  Journal of clinical pharmacology 20050101

• Valproic acid-associated hyperammonemic encephalopathy: a case report from the psychiatric setting.

  International clinical psychopharmacology 20050101

• The epsilon theory: a novel synthesis of the underlying molecular and electrophysiological mechanisms of primary generalized epilepsy and the possible mechanism of action of valproate.

  Medical hypotheses 20050101

• Topiramate and divalproex in combination with risperidone for acute mania: a randomized open-label study.

  Progress in neuro-psychopharmacology & biological psychiatry 20050101

• Nicotine augmentation for refractory obsessive-compulsive disorder. A case report.

  Progress in neuro-psychopharmacology & biological psychiatry 20050101

• Acute psychosis with a mediastinal carcinoma metastasis.

  Medical science monitor : international medical journal of experimental and clinical research 20050101

• Randomized, placebo-controlled trial of mixed amphetamine salts for symptoms of comorbid ADHD in pediatric bipolar disorder after mood stabilization with divalproex sodium.

  The American journal of psychiatry 20050101

• Fatal hepatic failure and valproate.

  The American journal of psychiatry 20050101

• Divalproex sodium in the management of post-herpetic neuralgia: a randomized double-blind placebo-controlled study.

  QJM : monthly journal of the Association of Physicians 20050101

• Efficacy of valproate maintenance in patients with bipolar disorder and alcoholism: a double-blind placebo-controlled study.

  Archives of general psychiatry 20050101

• Comparison of clinical, magnetic resonance and evoked potentials data in a case of valproic-acid-related hyperammonemic coma.

  European radiology 20050101

• Effects of combined lamotrigine and valproate on basal and stimulated extracellular amino acids and monoamines in the hippocampus of freely moving rats.

  Naunyn-Schmiedeberg's archives of pharmacology 20050101

• Histone deacetylase inhibitors profoundly decrease proliferation of human lymphoid cancer cell lines.

  Experimental hematology 20050101

• Comparison of intravenous valproate with intravenous lysine-acetylsalicylic acid in acute migraine attacks.

  Headache 20050101

• Extracorporeal management of valproic acid toxicity: a case report and review of the literature.

  Seminars in dialysis 20050101

• Bipolar disorder pills in perspective: questions from peer review.

  Journal of managed care pharmacy : JMCP 20050101

• Protracted lithium treatment protects against the ER stress elicited by thapsigargin in rat PC12 cells: roles of intracellular calcium, GRP78 and Bcl-2.

  The pharmacogenomics journal 20050101

• A case of clozapine-induced tonic-clonic seizures managed with valproate: implications for clinical care.

  Journal of psychopharmacology (Oxford, England) 20050101

• Approach to the assessment of platelet function: comparison between optical-based platelet-rich plasma and impedance-based whole blood platelet aggregation methods.

  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20050101

• [A case of valproate-associated hyperammonemia with chronic hepatitis C].

  Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20050101

• Auditory and visual P300 evoked potentials do not predict response to valproate treatment of aggression in patients with borderline and antisocial personality disorders.

  Clinical EEG and neuroscience 20050101

• Cortical hyperexcitability in migraine patients before and after sodium valproate treatment.

  Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society 20050101

• Recognizing and managing bipolar disorder in children.

  The Journal of clinical psychiatry 20050101

• Six-year-old Thomas diagnosed with pediatric onset bipolar disorder: a case study.

  Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc 20050101

• The overt aggression scale for rating aggression in outpatient youth with autistic disorder: preliminary findings.

  The Journal of neuropsychiatry and clinical neurosciences 20050101

• The teratology of autism.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050101

• Maternal administration of thalidomide or valproic acid causes abnormal serotonergic neurons in the offspring: implication for pathogenesis of autism.

  International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20050101

• Analytical performance evaluation of a new turbidimetric immunoassay for valproic acid on the ADVIA 1650 analyzer: effect of gross hemolysis and high bilirubin.

  Journal of clinical laboratory analysis 20050101

• Atypical antipsychotic augmentation of mood stabilizer therapy in bipolar disorder.

  The Journal of clinical psychiatry 20050101

• Women are not the same as men: specific clinical issues for female patients with bipolar disorder.

  Bipolar disorders 20050101

• Bioequivalence of a new sustained-release formulation of sodium valproate, valproate modified-release granules, compared with existing sustained-release formulations after once- or twice-daily administration.

  Pharmacotherapy 20050101

• Severe valproic acid intoxication is associated with atrial tachycardia: secondary detoxication by hemoperfusion.

  Klinische Padiatrie 20050101

• Is leukopenia associated with divalproex and/or quetiapine?

  Psychosomatics 20050101

• Psychotropic drug interactions with valproate.

  Clinical neuropharmacology 20050101

• The potential utility of sodium valproate as a novel addition to anti-multiple myeloma armamentarium.

  Medical hypotheses 20050101

• Is operative blood loss associated with valproic acid? Analysis of bilateral femoral osteotomy in children with total involvement cerebral palsy.

  Journal of pediatric orthopedics 20050101

• Valproate in bipolar disorder: 2000 onwards.

  Acta psychiatrica Scandinavica. Supplementum 20050101

• Lamotrigine and antiepileptic drugs as mood stabilizers in bipolar disorder.

  Acta psychiatrica Scandinavica. Supplementum 20050101

• Pancreatitis, complicated by a pancreatic pseudocyst associated with the use of valproic acid.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20050101

• Telogen effluvium caused by magnesium valproate and lamotrigine.

  Acta dermato-venereologica 20050101

• Lack of pharmacokinetic interactions between steady-state zonisamide and valproic acid in patients with epilepsy.

  Clinical pharmacokinetics 20050101

• [The use of valproates-generics in the treatment of epileptic patients].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101

• Rapid oral loading of extended release divalproex in patients with acute mania.

  General hospital psychiatry 20050101

• Isobolographic analysis of interactions among losigamone analog AO-620 and two conventional antiepileptic drugs.

  Pharmacological reports : PR 20050101

• [Valproate-dependent changes in the spectrum of free amino acids in rats: l-carnitine effects].

  Eksperimental'naia i klinicheskaia farmakologiia 20050101

• Adjunctive valproic acid for delirium and/or agitation on a consultation-liaison service: a report of six cases.

  The Journal of neuropsychiatry and clinical neurosciences 20050101

• Auditory and visual P300 evoked potentials do not predict response to valproate versus lithium in patients with mania.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20050101

• Canadian Network for Mood and Anxiety Treatments (CANMAT) guidelines for the management of patients with bipolar disorder: consensus and controversies.

  Bipolar disorders 20050101

• Liquid chromatography/electrospray ionization mass spectrometry method for the quantification of valproic acid in human plasma.

  Rapid communications in mass spectrometry : RCM 20050101

• Antiepileptic drugs in mood-disordered patients.

  Epilepsia 20050101

• [A case of Parkinsonian syndrome, cognitive impairment and hyperammonemia induced by divalproate sodium prescribed for bipolar disorder].

  L'Encephale 20050101

• Cardiac syncope from occult transposition masquerading as convulsive epilepsy.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20050101

• Clinical and surface EMG characteristics of valproate induced tremors.

  Electromyography and clinical neurophysiology 20050101

• Efficacy and tolerability of intravenous valproic acid in acute adolescent migraine.

  Headache 20050101

• Histone acetylation and histone deacetylase activity of magnesium valproate in tumor and peripheral blood of patients with cervical cancer. A phase I study.

  Molecular cancer 20050101

• Effect of divalproex sodium on behavioural and cognitive problems in elderly dementia.

  Drugs & aging 20050101

• [Monitoring free valproic acid concentrations in a post-surgical patient with sepsis].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20050101

• [Efficacy of keppra in combined therapy in pharmacoresistant adult epilepsy patients].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101

• Pharmacokinetic interactions of carbamazepine with some antiepileptic drugs during epilepsy treatment in children and adolescents.

  Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101

• Sodium Valproate versus Propranolol in paediatric migraine prophylaxis.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20050101

• Comorbid anxiety disorders and divalproex sodium use among partial hospital patients with psychotic disorders.

  Comprehensive psychiatry 20050101

• Valproic acid and HIV-1 latency: beyond the sound bite.

  Retrovirology 20050101

• Low bone density with the use of valproate.

  General hospital psychiatry 20050101

• Intravenous valproate use in bipolar II disorder after gastric bypass surgery.

  The Journal of neuropsychiatry and clinical neurosciences 20050101

• A case report of maintenance valproic acid treatment failing to protect against alcohol withdrawal.

  The American journal on addictions 20050101

• Management options for bipolar disorder in children and adolescents.

  Paediatric drugs 20050101

• A positron emission tomography study of the effects of treatment with valproate on brain 5-HT2A receptors in acute mania.

  Bipolar disorders 20050101

• Ultrastructural study of cerebellar dentate nucleus astrocytes in chronic experimental model with valproate.

  Folia neuropathologica 20050101

• Epilepsy and medication effects on the pattern visual evoked potential.

  Documenta ophthalmologica. Advances in ophthalmology 20050101

• Improvement of oligoasthenozoospermia in epileptic patients on switching anti-epilepsy medication from sodium valproate to phenytoin.

  Scandinavian journal of urology and nephrology 20050101

• Science review: carnitine in the treatment of valproic acid-induced toxicity - what is the evidence?

  Critical care (London, England) 20050101

• [Anticonvulsive pharmacotherapy may aggravate epilepsy course].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101

• Eosinophilic pleural effusion secondary to treatment with valproic acid.

  Actas espanolas de psiquiatria 20050101

• High sensitivity determination of valproic acid in mouse plasma using semi-automated sample preparation and liquid chromatography with tandem mass spectrometric detection.

  Rapid communications in mass spectrometry : RCM 20050101

• Management guidelines for children with idiopathic generalized epilepsy.

  Epilepsia 20050101

• Practical management issues for idiopathic generalized epilepsies.

  Epilepsia 20050101

• Reliability and validity of the pathological gambling adaptation of the Yale-Brown Obsessive-Compulsive Scale (PG-YBOCS).

  Journal of gambling studies 20050101

• [The efficacy of topiramate (topamax) in the treatment of resistant epilepsy in children].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101

• Efficacy of topiramate and valproate in chronic migraine.

  Clinical neuropharmacology 20050101

• Distribution of spatial complexity of EEG in idiopathic generalized epilepsy and its change after chronic valproate therapy.

  Brain topography 20050101

• Progress in pharmaceutical development presentation with improved pharmacokinetics: a new formulation for valproate.

  Acta neurologica Scandinavica. Supplementum 20050101

• [Use of diacarb in the treatment of children with epilepsy and febrile seizures].

  Likars'ka sprava 20050101

• Mode of action: inhibition of histone deacetylase, altering WNT-dependent gene expression, and regulation of beta-catenin--developmental effects of valproic acid.

  Critical reviews in toxicology 20050101

• [Ergenyl chronospheres in bipolar disorders].

  Krankenpflege Journal 20050101

• [Ergenyl chronospheres in juvenile and senile epilepsies].

  Krankenpflege Journal 20050101

• [Valpromide poisoning associated with circulatory collapse].

  Therapie 20050101

• Anti-HIV agents. Can valproic acid help flush HIV from hiding?

  TreatmentUpdate 20050101

• Anti-HIV agents. Valproic acid and HIV eradication--many questions remain.

  TreatmentUpdate 20050101

• Anti-HIV agents. Canadian trial of valproic acid.

  TreatmentUpdate 20050101

• Treatment of refractory seizures due to a benign mass present in the corpus callosum with an ion magnetic inductor: case report.

  Brain tumor pathology 20050101

• Acetazolamide-enhanced neuroSPECT scan reveals functional impairment after minimal traumatic brain injury not otherwise discernible.

  Psychiatry research 20041230

• Human ovarian carcinoma cells: histone deacetylase inhibitors exhibit antiproliferative activity and potently induce apoptosis.

  Cancer 20041215

• Valproic acid inhibits leptin secretion and reduces leptin messenger ribonucleic acid levels in adipocytes.

  Endocrinology 20041201

• Mechanism of the drug interaction between valproic acid and carbapenem antibiotics in monkeys and rats.

  Drug metabolism and disposition: the biological fate of chemicals 20041201

• Ethosuximide and valproate display high efficacy against lindane-induced seizures in mice.

  Toxicology letters 20041201

• Quetiapine versus placebo in combination with lithium or divalproex for the treatment of bipolar mania.

  Journal of clinical psychopharmacology 20041201

• Predictors of response to treatment of acute bipolar manic episodes with divalproex sodium or placebo in 2 randomized, controlled, parallel-group trials.

  Journal of clinical psychopharmacology 20041201

• Separate and concomitant use of lamotrigine, lithium, and divalproex in bipolar disorders.

  Current psychiatry reports 20041201

• Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo.

  International journal of oncology 20041201

• Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.

  Journal of neural transmission (Vienna, Austria : 1996) 20041201

• Population pharmacokinetic model of valproate and prediction of valproate serum concentrations in children with epilepsy.

  Acta pharmacologica Sinica 20041201

• Prescription error resulting in valproic acid intoxication.

  Journal of the American Geriatrics Society 20041201

• Efficacy of olanzapine combined with valproate or lithium in the treatment of dysphoric mania.

  The British journal of psychiatry : the journal of mental science 20041201

• Valproate decreases inositol biosynthesis.

  Biological psychiatry 20041201

• Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor.

  Biological & pharmaceutical bulletin 20041201

• Benefit of valproic acid in suppressing disease progression of ALS model mice.

  The European journal of neuroscience 20041201

• Valproic acid doses, concentrations, and clearances in elderly nursing home residents.

  Epilepsy research 20041201

• Leukopenia in clozapine treated patients may be induced by other drugs: a case series.

  European psychiatry : the journal of the Association of European Psychiatrists 20041201

• Seizure prophylaxis in patients with brain tumors: a meta-analysis.

  Mayo Clinic proceedings 20041201

• Efficacy and tolerability of zonisamide in juvenile myoclonic epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20041201

• Video-EEG study in an adult and a child with eyelid myoclonia with absences.

  Epileptic disorders : international epilepsy journal with videotape 20041201

• Chess-playing epilepsy: a case report with video-EEG and back averaging.

  Epileptic disorders : international epilepsy journal with videotape 20041201

• Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison.

  Birth defects research. Part C, Embryo today : reviews 20041201

• Clinical advances in the preventive treatment of migraine.

  Acta neurologica Taiwanica 20041201

• Gingival enlargement in children treated with antiepileptics.

  Journal of child neurology 20041201

• Valproic acid induces differentiation of a supratentorial primitive neuroectodermal tumor.

  Pediatric hematology and oncology 20041201

• Effect of sodium valproate on neuromagnetic responses to chromatic flicker: implication for photosensitivity.

  Neurology & clinical neurophysiology : NCN 20041130

• Examining the correlations between GSK-3 inhibitory properties and anti-convulsant efficacy of valproate and valproate-related compounds.

  Bioorganic & medicinal chemistry letters 20041115

• Diamond-Blackfan anemia responding to valproic acid.

  Blood 20041115

• [Childhood and juvenile absence epilepsy. Treatment and prognosis].

  Ugeskrift for laeger 20041108

• [Benign partial epilepsy with centrotemporal spikes in children (Roland's epilepsy). Treatment and prognosis].

  Ugeskrift for laeger 20041108

• Candidate genes, pathways and mechanisms for bipolar (manic-depressive) and related disorders: an expanded convergent functional genomics approach.

  Molecular psychiatry 20041101

• Comparison of the bioavailability of 250 and 500 mg divalproex sodium extended-release tablets in healthy volunteers.

  Biopharmaceutics & drug disposition 20041101

• Bioavailability of divalproex extended-release formulation relative to the divalproex delayed-release formulation.

  Biopharmaceutics & drug disposition 20041101

• Valproyl-dephosphoCoA: a novel metabolite of valproate formed in vitro in rat liver mitochondria.

  Drug metabolism and disposition: the biological fate of chemicals 20041101

• Longer term outcome of children born to mothers with epilepsy.

  Journal of neurology, neurosurgery, and psychiatry 20041101

• The longer term outcome of children born to mothers with epilepsy.

  Journal of neurology, neurosurgery, and psychiatry 20041101

• Antidepressant-associated mania with escitalopram.

  European psychiatry : the journal of the Association of European Psychiatrists 20041101

• Fracture risk associated with use of antiepileptic drugs.

  Epilepsia 20041101

• Topiramate pharmacokinetics in children with epilepsy aged from 6 months to 4 years.

  Epilepsia 20041101

• Australian pregnancy registry of women taking antiepileptic drugs.

  Epilepsia 20041101

• A mood stabilizer with risperidone or haloperidol for mania.

  The American journal of psychiatry 20041101

• A mood stabilizer with risperidone or haloperidol for mania.

  The American journal of psychiatry 20041101

• Critical relationship between sodium valproate dose and human teratogenicity: results of the Australian register of anti-epileptic drugs in pregnancy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20041101

• A randomized, double-blind, placebo controlled trial of melatonin add-on therapy in epileptic children on valproate monotherapy: effect on glutathione peroxidase and glutathione reductase enzymes.

  British journal of clinical pharmacology 20041101

• Polycomb homologs are involved in teratogenicity of valproic acid in mice.

  Birth defects research. Part A, Clinical and molecular teratology 20041101

• Subregional changes in discharge rate, pattern, and drug sensitivity of putative GABAergic nigral neurons in the kindling model of epilepsy.

  The European journal of neuroscience 20041101

• Valproate is neuroprotective against malonate toxicity in rat striatum: an association with augmentation of high-affinity glutamate uptake.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20041101

• Pharmacokinetics and safety of extended-release divalproex sodium tablets: morning versus evening administration.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20041101

• Predicted serum valproic acid concentrations in patients missing and replacing a dose of extended-release divalproex sodium.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20041101

• Pure red cell aplasia after 13 years of sodium valproate, and bone marrow suppression after 17 years of carbamazepine.

  PLoS medicine 20041101

• Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review.

  Annals of the New York Academy of Sciences 20041101

• Valproic acid inhibits corticotropin-releasing factor synthesis and release from the rat hypothalamus in vitro: evidence for the involvement of GABAergic neurotransmission.

  Journal of psychiatry & neuroscience : JPN 20041101

• Protein kinase C overactivity impairs prefrontal cortical regulation of working memory.

  Science (New York, N.Y.) 20041029

• Rapid infusion with valproate sodium is well tolerated in patients with epilepsy.

  Neurology 20041026

• Simple and sensitive fluorimetric liquid chromatography method for the determination of valproic acid in plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041015

• Prevention of postpartum episodes in women with bipolar disorder.

  Biological psychiatry 20041015

• Cytokine production in bipolar affective disorder patients under lithium treatment.

  Journal of affective disorders 20041015

• Valproic acid-induced hyperammonemia and thrombocytopenia in an elderly woman.

  The Annals of pharmacotherapy 20041001

• Valproic acid-induced hyperammonemia: a case report.

  Journal of clinical psychopharmacology 20041001

• Pharmacologic management of behavioral instability in medically ill pediatric patients.

  Current opinion in pediatrics 20041001

• The mood stabilizer valproic acid stimulates GABA neurogenesis from rat forebrain stem cells.

  Journal of neurochemistry 20041001

• Cognitive profile of topiramate as compared with lamotrigine in epilepsy patients on antiepileptic drug polytherapy: relationships to blood serum levels and comedication.

  Epilepsy & behavior : E&B 20041001

• Clinical comparison of extended-release divalproex versus delayed-release divalproex: pooled data analyses from nine trials.

  Epilepsy & behavior : E&B 20041001

• A prospective 4-5 year follow-up of juvenile onset bipolar disorder.

  Bipolar disorders 20041001

• Lamotrigine therapy in treatment-resistant menstrually-related rapid cycling bipolar disorder: a case report.

  Bipolar disorders 20041001

• Mixed connective tissue disease associated with antineutrophil cytoplasmic antibodies against proteinase-3 and systemic atherosclerosis: a case report.

  Clinical rheumatology 20041001

• Navigating toward fetal and maternal health: the challenge of treating epilepsy in pregnancy.

  Epilepsia 20041001

• Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice.

  Epilepsia 20041001

• Effect of carbamazepine and valproate on bone mineral density.

  Pediatric neurology 20041001

• The outcome of initiation of antiepileptic drug monotherapy in primary care: a UK database survey.

  The British journal of general practice : the journal of the Royal College of General Practitioners 20041001

• [Deep lactic acidosis after valproate self-poisoning].

  Annales francaises d'anesthesie et de reanimation 20041001

• Valproic acid induces expression of neutrophil chemoattractants of the CXC chemokine family in endothelial cells.

  International journal of clinical pharmacology and therapeutics 20041001

• Valproate and gum hypertrophy.

  Indian pediatrics 20041001

• Anticonvulsant drugs in primary headaches prophylaxis.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20041001

• [Valproate-induced hyperammonemic encephalopathy in a patient with Sjögren's syndrome].

  Rinsho shinkeigaku = Clinical neurology 20041001

• Open-label prospective trial of risperidone in combination with lithium or divalproex sodium in pediatric mania.

  Journal of affective disorders 20041001

• The diagnosis of preschool bipolar disorder presenting with mania: open pharmacological treatment.

  Journal of affective disorders 20041001

• Effects of valproic acid on cardiac metabolism.

  Canadian journal of physiology and pharmacology 20041001

• Enhanced extracorporeal elimination of valproic acid in overdose.

  The Netherlands journal of medicine 20041001

• Valproic acid intoxication: sense and non-sense of haemodialysis.

  The Netherlands journal of medicine 20041001

• [Determination of sodium valproate in serum by gas chromatography].

  Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20041001

• Comparison of microarray-based mRNA profiling technologies for identification of psychiatric disease and drug signatures.

  Journal of neuroscience methods 20040930

• Correlating lamotrigine serum concentrations with tolerability in patients with epilepsy.

  Neurology 20040928

• [Migraine and psychiatric disorders].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040923

• Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid.

  Blood 20040901

• Valproate as an adjunct to antipsychotics for schizophrenia: a systematic review of randomized trials.

  Schizophrenia research 20040901

• Color vision in epileptic adolescents treated with valproate and carbamazepine.

  Seizure 20040901

• Efficacy of levetiracetam in pharmacoresistant continuous spikes and waves during slow sleep.

  Acta neurologica Scandinavica 20040901

• Sydenham's chorea-clinical characteristics of nine patients.

  International journal of cardiology 20040901

• Effect of valproic acid on serotonin-2A receptor signaling in C6 glioma cells.

  Journal of neurochemistry 20040901

• Modulation of pro- and anti-apoptotic factors in human melanoma cells exposed to histone deacetylase inhibitors.

  Apoptosis : an international journal on programmed cell death 20040901

• Experimental studies on cervical and lumbar ribs in mouse embryos.

  Congenital anomalies 20040901

• Lamotrigine versus valproic acid as first-line monotherapy in newly diagnosed typical absence seizures: an open-label, randomized, parallel-group study.

  Epilepsia 20040901

• Physical growth and endocrinal disorders during pubertal maturation in girls with epilepsy.

  Epilepsia 20040901

• Lithium and valproic acid treatment effects on brain chemistry in bipolar disorder.

  Biological psychiatry 20040901

• Quality of life assessment in patients with bipolar disorder treated with olanzapine added to lithium or valproic acid.

  Journal of affective disorders 20040901

• Neuroacanthocytosis.

  The American journal of psychiatry 20040901

• Effects of piracetam alone and in combination with antiepileptic drugs in rodent seizure models.

  Journal of neural transmission (Vienna, Austria : 1996) 20040901

• Antihostility effects of adjunctive divalproex.

  Psychiatric services (Washington, D.C.) 20040901

• Meropenem decreases serum level of valproic acid.

  Pediatric neurology 20040901

• Rethinking the treatment paradigm for bipolar depression: the importance of long-term management.

  CNS spectrums 20040901

• Encephalopathy and myoclonus triggered by valproic acid.

  Progress in neuro-psychopharmacology & biological psychiatry 20040901

• Pharmacovigilance in the 21st century: new systematic tools for an old problem.

  Pharmacotherapy 20040901

• Extended-release divalproex sodium for mood stabilization.

  Pharmacotherapy 20040901

• [Long-term follow-up of a case of eyelid myoclonia with absences].

  No to hattatsu = Brain and development 20040901

• [Serial MEG change in a boy with Landau-Kleffner syndrome].

  No to hattatsu = Brain and development 20040901

• Bipolar depression: an overview.

  IDrugs : the investigational drugs journal 20040901

• Intravenous valproate in post-anoxic myoclonic status epilepticus: a report of ten patients.

  Neurology India 20040901

• Non-equivalence of bioavailability between generic and branded form of sodium valproate.

  Neurology India 20040901

• Assessment of the epilepsy treatment gap in two cities of south-east of Brazil.

  Arquivos de neuro-psiquiatria 20040901

• [Study on the mechanism to maintain calcium mobilization in platelets of patients with bipolar affective disorders--the relationship with the protein kinase C system].

  [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20040901

• Two cases of valproate-induced hyperammonemic encephalopathy without hepatic failure.

  The Journal of the Association of Physicians of India 20040901

• [Psychotropics and weight gain].

  Praxis 20040825

• Tetramethylcyclopropyl analogue of a leading antiepileptic drug, valproic acid. Synthesis and evaluation of anticonvulsant activity of its amide derivatives.

  Journal of medicinal chemistry 20040812

• [Anticonvulsant hypersensitivity syndrome].

  Orvosi hetilap 20040808

• Abolition of valproate-derived choleresis in the Mrp2 transporter-deficient rat.

  The Journal of pharmacology and experimental therapeutics 20040801

• Etiological heterogeneity of familial periventricular heterotopia and hydrocephalus.

  Brain & development 20040801

• Valproic acid treatment of glioblastoma multiforme in a child.

  Pediatric blood & cancer 20040801

• Increased human cytomegalovirus replication in fibroblasts after treatment with therapeutical plasma concentrations of valproic acid.

  Biochemical pharmacology 20040801

• Lamotrigine for patients with juvenile myoclonic epilepsy following prior treatment with valproate: results of an open-label study.

  Epilepsy & behavior : E&B 20040801

• Efficacy and tolerability of conversion to monotherapy with lamotrigine compared with valproate and carbamazepine in patients with epilepsy.

  Epilepsy & behavior : E&B 20040801

• Bone mineral metabolism changes in epileptic children receiving valproic acid.

  Journal of paediatrics and child health 20040801

• Valproate-induced hyperammonemic encephalopathy.

  Journal of the American Academy of Child and Adolescent Psychiatry 20040801

• Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs.

  Clinical biochemistry 20040801

• Chart review of the impact of attention-deficit/hyperactivity disorder comorbidity on response to lithium or divalproex sodium in adolescent mania.

  The Journal of clinical psychiatry 20040801

• Psychotic symptoms associated with topiramate: cognitive side effects or worsening of psychosis?

  The Journal of clinical psychiatry 20040801

• Successful treatment of sexual dysfunction with dronabinol: a case report.

  The Journal of clinical psychiatry 20040801

• Valproic acid teratogenicity: a toxicogenomics approach.

  Environmental health perspectives 20040801

• Intravenous valproate in acute adolescent mania: a preliminary report.

  European child & adolescent psychiatry 20040801

• Bipolar disorder.

  The New England journal of medicine 20040729

• Lamotrigine-induced seizure aggravation and negative myoclonus in idiopathic rolandic epilepsy.

  Neurology 20040727

• Modulation of synaptic plasticity by antimanic agents: the role of AMPA glutamate receptor subunit 1 synaptic expression.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040721

• Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040721

• Characterization of the anticonvulsant profile of valpromide derivatives.

  Bioorganic & medicinal chemistry 20040715

• Mood stabilizers inhibit glucocorticoid receptor function in LMCAT cells.

  European journal of pharmacology 20040714

• Valproate prevents the induction, but not the expression of morphine sensitization in mice.

  Behavioural brain research 20040709

• Invasion of v-Fos(FBR)-transformed cells is dependent upon histone deacetylase activity and suppression of histone deacetylase regulated genes.

  Oncogene 20040708

• The effect of valproate on bone mineral density in adult epileptic patients.

  Pharmacological research 20040701

• Valproic acid inhibits proliferation and induces apoptosis in acute myeloid leukemia cells expressing P-gp and MRP1.

  Leukemia 20040701

• EEG in childhood absence epilepsy.

  Seizure 20040701

• Neuroblastoma, maternal valproic acid use, in-vitro fertilization and family history of mosaic chromosome 22: coincidence or causal relationship?

  Clinical dysmorphology 20040701

• The prophylactic effect of valproate on glyceryltrinitrate induced migraine.

  Cephalalgia : an international journal of headache 20040701

• Absolute bioavailability and absorption characteristics of divalproex sodium extended-release tablets in healthy volunteers.

  Journal of clinical pharmacology 20040701

• Pramipexole for bipolar II depression: a placebo-controlled proof of concept study.

  Biological psychiatry 20040701

• The activity of antiepileptic drugs as histone deacetylase inhibitors.

  Epilepsia 20040701

• Serum androgen levels and testicular structure during pubertal maturation in male subjects with epilepsy.

  Epilepsia 20040701

• Health-related quality of life of people with epilepsy compared with a general reference population: a Tunisian study.

  Epilepsia 20040701

• Fanconi syndrome caused by antiepileptic therapy with valproic Acid.

  Epilepsia 20040701

• Spasmodic dysphonia induced by valproic acid.

  Epilepsia 20040701

• Casebook: epileptic seizures and turns.

  The Practitioner 20040701

• Self induced photosensitive epilepsy.

  Indian journal of pediatrics 20040701

• Valproic acid-induced pancreatitis in childhood epilepsy: case series and review.

  Journal of child neurology 20040701

• Lithium, a common drug for bipolar disorder treatment, regulates amyloid-beta precursor protein processing.

  Biochemistry 20040608

• [Pharmacokinetic interaction between valproic acid and meropenem].

  Medicina clinica 20040605

• Metabolic viability and pharmaco-toxicological reactivity of cryopreserved human precision-cut renal cortical slices.

  Toxicology in vitro : an international journal published in association with BIBRA 20040601

• Quetiapine with lithium or divalproex for the treatment of bipolar mania: a randomized, double-blind, placebo-controlled study.

  Bipolar disorders 20040601

• Cognitive impairment in euthymic bipolar patients: implications for clinical and functional outcome.

  Bipolar disorders 20040601

• A study of the safety, efficacy, and tolerability of switching from the standard delayed release preparation of divalproex sodium to the extended release formulation in patients with schizophrenia.

  Journal of clinical psychopharmacology 20040601

• QTc prolongation in multiple drug overdose.

  Journal of clinical psychopharmacology 20040601

• Osteopenia associated with divalproex sodium.

  Journal of clinical psychopharmacology 20040601

• Drugs pharmacokinetics in ICU patients: consequences of hypoalbuminemia upon drugs monitoring and dosing scheme.

  Intensive care medicine 20040601

• Therapeutic doses of topiramate are not toxic to the developing rat brain.

  Experimental neurology 20040601

• Add-on melatonin improves quality of life in epileptic children on valproate monotherapy: a randomized, double-blind, placebo-controlled trial.

  Epilepsy & behavior : E&B 20040601

• Case of bipolar disorder successfully stabilized with clonazepam, valproate and lithium after numerous relapses for 47 years.

  Psychiatry and clinical neurosciences 20040601

• Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.

  Journal of clinical pharmacy and therapeutics 20040601

• Valproic acid induces manifestations of simultaneous dopamine enhancement and reduction in schizophrenia.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040601

• Delirium from valproic acid with lamotrigine.

  The American journal of psychiatry 20040601

• Valproic acid reduces brain damage induced by transient focal cerebral ischemia in rats: potential roles of histone deacetylase inhibition and heat shock protein induction.

  Journal of neurochemistry 20040601

• Key developments in psychiatry.

  The Practitioner 20040601

• An overview of primary care assessment and management of bipolar disorder.

  The Journal of the American Osteopathic Association 20040601

• Effect of sodium valproate on esophageal motility in healthy subjects and patients with gastroesophageal reflux.

  Scandinavian journal of gastroenterology 20040601

• Olanzapine for injection: new formulation. No advantage in agitated patients.

  Prescrire international 20040601

• Results of a naturalistic study of treatment options: switching atypical antipsychotic drugs or augmenting with valproate.

  Clinical therapeutics 20040601

• Anticonvulsants as mood stabilizers and adjuncts to antipsychotics: valproate, lamotrigine, carbamazepine, and oxcarbazepine and actions at voltage-gated sodium channels.

  The Journal of clinical psychiatry 20040601

• Psychosis in mania: specificity of its role in severity and treatment response.

  The Journal of clinical psychiatry 20040601

• Absence seizures in children.

  Clinical evidence 20040601

• Practice parameter: medical treatment of infantile spasms: report of the American Academy of Neurology and the Child Neurology Society.

  Neurology 20040525

• Human 1-D-myo-inositol-3-phosphate synthase is functional in yeast.

  The Journal of biological chemistry 20040521

• Coaxing HIV-1 from resting CD4 T cells: histone deacetylase inhibition allows latent viral expression.

  AIDS (London, England) 20040521

• Detection of Purkinje cell loss following drug exposures to developing rat pups using reverse transcriptase-polymerase chain reaction (RT-PCR) analysis for calbindin-D28k mRNA expression.

  Toxicology letters 20040502

• In vivo 1H magnetic resonance spectroscopy of rat brain after valproate administration.

  Neuroradiology 20040501

• Valproate reduced synaptic activity increase induced by 4-aminopyridine at the hippocampal CA3-CA1 synapse.

  Epilepsia 20040501

• Levetiracetam in focal epilepsy and hepatic porphyria: a case report.

  Epilepsia 20040501

• Design, synthesis and anticonvulsive activity of analogs of gamma-vinyl GABA.

  Farmaco (Societa chimica italiana : 1989) 20040501

• Valproate therapy and nonalcoholic fatty liver disease.

  Annals of neurology 20040501

• Photosensitivity and epilepsy: a follow-up study.

  Developmental medicine and child neurology 20040501

• Induction of HDAC2 expression upon loss of APC in colorectal tumorigenesis.

  Cancer cell 20040501

• A rapid and systematic review and economic evaluation of the clinical and cost-effectiveness of newer drugs for treatment of mania associated with bipolar affective disorder.

  Health technology assessment (Winchester, England) 20040501

• The binding of acetaminophen, lidocaine, and valproic acid to human milk.

  American journal of clinical pathology 20040501

• Risperidone in combination with mood stabilizers: a 10-week continuation phase study in bipolar I disorder.

  The Journal of clinical psychiatry 20040501

• Dosing differences between valproic acid concentrate and divalproex sodium: a case report.

  The Journal of clinical psychiatry 20040501

• Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid.

  Journal of neurology 20040501

• Divalproex-ER pharmacokinetics in older children and adolescents.

  Pediatric neurology 20040501

• Mapping a chromosomal locus for valproic acid-induced exencephaly in mice.

  Mammalian genome : official journal of the International Mammalian Genome Society 20040501

• [Insulin resistance in epileptic patients during treatment of valproic acid].

  Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20040501

• Divalproex sodium in the treatment of adults with bipolar disorder.

  Expert review of neurotherapeutics 20040501

• Inhibition of histone deacetylase activity by valproic acid blocks adipogenesis.

  The Journal of biological chemistry 20040430

• Reversible parkinsonism with normal beta-CIT-SPECT in patients exposed to sodium valproate.

  Neurology 20040427

• Modulation of angiogenesis-related protein synthesis by valproic acid.

  Biochemical and biophysical research communications 20040409

• Pentyl-4-yn-valproic acid reverses age-associated memory impairment in the Wistar rat.

  Neurobiology of aging 20040401

• Hyperammonemic encephalopathy induced by a combination of valproate and pivmecillinam.

  Acta neurologica Scandinavica 20040401

• The effect of long-term antiepileptic treatment on serum cholesterol (TC, HDL, LDL) and triglyceride levels in adult epileptic patients on monotherapy.

  Medical science monitor : international medical journal of experimental and clinical research 20040401

• Management of bipolar disorder during pregnancy and the postpartum period.

  The American journal of psychiatry 20040401

• Relapse prevention in bipolar I disorder: 18-month comparison of olanzapine plus mood stabiliser v. mood stabiliser alone.

  The British journal of psychiatry : the journal of mental science 20040401

• Sodium valproate in aggressive behaviour in dementia: a twelve-week open label follow-up study.

  International journal of geriatric psychiatry 20040401

• Nonparametric population modeling of valproate pharmacokinetics in epileptic patients using routine serum monitoring data: implications for dosage.

  Journal of clinical pharmacy and therapeutics 20040401

• Drug induced encephalopathy in six epileptic patients: topiramate? valproate? or both?

  Human psychopharmacology 20040401

• [Changes in Ca2+ concentration mediated by N-methyl-D-aspartate receptor in PO/AH neurons of anoxic SD rats].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20040401

• [Haemodialysis, L-carnitine therapy and valproic acid overdose].

  Annales francaises d'anesthesie et de reanimation 20040401

• The effectiveness of divalproate in all forms of mania and the broader bipolar spectrum: many questions, few answers.

  Journal of affective disorders 20040401

• Mood stabilizers: protecting the mood...protecting the brain.

  Journal of affective disorders 20040401

• Olanzapine: new indication. New indication in acute mania: just another neuroleptic.

  Prescrire international 20040401

• Factors associated with poor control in partial complex epilepsy.

  Journal of child neurology 20040401

• Valproate modulates TRH receptor, TRH and TRH-like peptide levels in rat brain.

  Peptides 20040401

• Divalproex versus valproate in patients with bipolar disorder.

  Journal of clinical psychopharmacology 20040401

• Effect of valproic acid on fetal and maternal organs in the mouse: a morphological study.

  Morphologie : bulletin de l'Association des anatomistes 20040401

• Dynamic release of amino acid transmitters induced by valproate in PTZ-kindled epileptic rat hippocampus.

  Neurochemistry international 20040301

• Valproic acid blood genomic expression patterns in children with epilepsy - a pilot study.

  Acta neurologica Scandinavica 20040301

• Reflex writing seizures in two siblings with juvenile myoclonic epilepsy.

  Acta neurologica Scandinavica 20040301

• Unbalanced statistical analysis of combined divalproex and antipsychotic therapy for schizophrenia.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040301

• Valproate reduced excitatory postsynaptic currents in hippocampal CA1 pyramidal neurons.

  Neuropharmacology 20040301

• Valproic acid inhibits angiogenesis in vitro and in vivo.

  Molecular pharmacology 20040301

• Severe anemia secondary to a probable drug interaction between zidovudine and valproic acid.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040301

• Valproic Acid and hypersensitivity syndrome.

  The American journal of psychiatry 20040301

• Adjunctive divalproex and hostility among patients with schizophrenia receiving olanzapine or risperidone.

  Psychiatric services (Washington, D.C.) 20040301

• Thyroid function in girls with epilepsy with carbamazepine, oxcarbazepine, or valproate monotherapy and after withdrawal of medication.

  Epilepsia 20040301

• Interaction between anticonvulsants and human placental carnitine transporter.

  Epilepsia 20040301

• Cost of epilepsy in patients attending a secondary-level hospital in India.

  Epilepsia 20040301

• DNA methylation as an epigenetic regulator of neural 5-lipoxygenase expression: evidence in human NT2 and NT2-N cells.

  Journal of neurochemistry 20040301

• Glutathione S-transferase is a novel target for mood stabilizing drugs in primary cultured neurons.

  Journal of neurochemistry 20040301

• Unusual causes of hyperammonemia in the ED.

  The American journal of emergency medicine 20040301

• Cell-type specific regulation of calreticulin and Bcl-2 expression by mood stabilizer drugs.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20040301

• Antitumor histone deacetylase inhibitors suppress cutaneous radiation syndrome: Implications for increasing therapeutic gain in cancer radiotherapy.

  Molecular cancer therapeutics 20040301

• [Clinical guidelines for treatment of epilepsy in children].

  No to hattatsu = Brain and development 20040301

• Risperidone plus lithium versus risperidone plus valproate in acute and continuation treatment of mania.

  International clinical psychopharmacology 20040301

• Anticonvulsants as anxiolytics, part 1: tiagabine and other anticonvulsants with actions on GABA.

  The Journal of clinical psychiatry 20040301

• Obesity and plasma concentrations of alpha-tocopherol and beta-carotene in epileptic girls treated with valproate.

  Neuroendocrinology 20040301

• Primary generalized epilepsy during infancy and early childhood.

  Journal of child neurology 20040301

• Delayed toxicity following acute ingestion of valpromide.

  Human & experimental toxicology 20040301

• Acute pancreatitis and diabetic ketoacidosis in non-diabetic person while on treatment with sodium valproate, chlorpromazine and haloperidol.

  The Journal of the Association of Physicians of India 20040301

• 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamides as a new class of synthetic histone deacetylase inhibitors. 2. Effect of pyrrole-C2 and/or -C4 substitutions on biological activity.

  Journal of medicinal chemistry 20040226

• Pharmacotherapy and risk of suicidal behaviors among patients with bipolar disorder.

  JAMA 20040225

• Pharmacotherapy and risk of suicidal behaviors among patients with bipolar disorder.

  JAMA 20040225

• Long-term reproductive endocrine health in young women with epilepsy during puberty.

  Neurology 20040210

• Valproate potentiates androgen biosynthesis in human ovarian theca cells.

  Endocrinology 20040201

• Cytotoxicity evaluation after coexposure to perchloroethylene and selected peroxidant drugs in rat hepatocytes.

  Toxicology in vitro : an international journal published in association with BIBRA 20040201

• Valproic-acid-induced thrombocytopenia and hepatotoxicity: discontinuation of treatment?

  Pharmacology 20040201

• Valproate monotherapy in the treatment of civilian patients with non-combat-related posttraumatic stress disorder: an open-label study.

  Journal of clinical psychopharmacology 20040201

• Elevated thyrotropin in bipolar youths prescribed both lithium and divalproex sodium.

  Journal of the American Academy of Child and Adolescent Psychiatry 20040201

• Factor XIII deficiency associated with valproate treatment.

  Epilepsia 20040201

• Update on pharmacotherapy of borderline personality disorder.

  Current psychiatry reports 20040201

• Valproic acid induces the expression of the Na+/I- symporter and iodine uptake in poorly differentiated thyroid cancer cells.

  The Journal of clinical endocrinology and metabolism 20040201

• Histone deacetylase is a target of valproic acid-mediated cellular differentiation.

  Cancer research 20040201

• Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20040201

• [Expansile cyst, twin formation and possible parasagittal cerebral injury].

  Revista de neurologia 20040201

• A critical review of atypical antipsychotic utilization: comparing monotherapy with polypharmacy and augmentation.

  Current medicinal chemistry 20040201

• Lithium the lifesaver.

  The Harvard mental health letter 20040201

• Chemically induced supernumerary lumbar ribs in CD-1 mice: size distribution and dose response.

  Birth defects research. Part B, Developmental and reproductive toxicology 20040201

• Amidic modification of valproic acid reduces skeletal teratogenicity in mice.

  Birth defects research. Part B, Developmental and reproductive toxicology 20040201

• Special considerations in treating bipolar disorder in women.

  Bipolar disorders 20040201

• Rett syndrome: a case presenting with atypical seizures. Neurophysiological and clinical aspects.

  Neurophysiologie clinique = Clinical neurophysiology 20040201

• Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study.

  Acta paediatrica (Oslo, Norway : 1992) 20040201

• Topiramate, carbamazepine, and valproate monotherapy: double-blind comparison in children with newly diagnosed epilepsy.

  Journal of child neurology 20040201

• [Effect of anti-epileptic drugs on human placenta and the fetus].

  Ginekologia polska 20040201

• Pharmacological treatment of alcohol abuse/dependence with psychiatric comorbidity.

  Alcoholism, clinical and experimental research 20040201

• Effect of combination of dizocilpine with general antiepileptic drugs on amygdala kindling models in rats.

  Yao xue xue bao = Acta pharmaceutica Sinica 20040201

• Epilepsy versus antiepileptic drugs and gonadal function in men.

  Neurology 20040127

• Epilepsy syndrome, focus location, and treatment choice affect testicular function in men with epilepsy.

  Neurology 20040127

• Effect of epilepsy and antiepileptic drugs on male reproductive health.

  Neurology 20040127

• Valproic acid has no effect on pain in polyneuropathy: a randomized, controlled trial.

  Neurology 20040127

• Levetiracetam improves paroxysmal symptoms in a patient with stiff-person syndrome.

  Neurology 20040127

• Zn2+-chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors.

  Journal of medicinal chemistry 20040115

• Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7.

  Molecular and cellular endocrinology 20040115

• Neurobehavioral teratogenicity in antiepileptic drugs: the new Pandora's box.

  Neurology 20040113

• Normal intelligence in children with prenatal exposure to carbamazepine.

  Neurology 20040113

• In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101

• Convergent effects of lithium and valproate on the expression of proteins associated with large dense core vesicles in NGF-differentiated PC12 cells.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101

• Marijuana withdrawal in humans: effects of oral THC or divalproex.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040101

• Expressional changes after histone deacetylase inhibition by valproic acid in LNCaP human prostate cancer cells.

  International journal of oncology 20040101

• Pharmacokinetic modelling of valproic acid from routine clinical data in Egyptian epileptic patients.

  European journal of clinical pharmacology 20040101

• Effects of lithium and valproate on agonist-induced platelet intracellular calcium mobilization: relevance to myosin light chain kinase.

  Progress in neuro-psychopharmacology & biological psychiatry 20040101

• Differential enantioselective effects of pentyl-4-yn-valproate on spatial learning in the rat, and neurite outgrowth and cyclin D3 expression in vitro.

  Journal of neurochemistry 20040101

• Sodium valproate for painful diabetic neuropathy: a randomized double-blind placebo-controlled study.

  QJM : monthly journal of the Association of Physicians 20040101

• The relationship between treatment with valproate, lamotrigine, and topiramate and the prognosis of the idiopathic generalised epilepsies.

  Journal of neurology, neurosurgery, and psychiatry 20040101

• Valproic acid is known to cause hypospadias in man but does not reduce anogenital distance or causes hypospadias in rats.

  Basic & clinical pharmacology & toxicology 20040101

• Serum nitrite and nitrate levels in epileptic children using valproic acid or carbamazepine.

  Brain & development 20040101

• Hypouricemia in severely disabled children II: influence of elemental enteral nutrition on the serum uric acid levels.

  Brain & development 20040101

• Single-dose intravenous valproate in acute mania.

  The Journal of clinical psychiatry 20040101

• [Childhood-onset epileptic blindness--clinical correlates and outcomes].

  Harefuah 20040101

• [Lipid peroxidation in adult epileptic patients treated with valproic acid].

  Revista de neurologia 20040101

• Modafinil treatment of excessive sedation associated with divalproex sodium.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20040101

• Pharmacotherapy for marijuana dependence: a double-blind, placebo-controlled pilot study of divalproex sodium.

  The American journal on addictions 20040101

• Valproate for schizophrenia.

  The Cochrane database of systematic reviews 20040101

• Possible role of divalproex sodium in sedation induced by antipsychotic medications.

  The Journal of clinical psychiatry 20040101

• Valproate for hostility in schizophrenia patients.

  The Journal of clinical psychiatry 20040101

• Treatment of primary headache disorders with intravenous valproate: initial outpatient experience.

  Headache 20040101

• Valproic acid-hydrophilic cyclodextrin complexes and valproic acid-solid dispersions: evaluation of their potential pharmaceutical use.

  Drug development and industrial pharmacy 20040101

• Valproate activates phosphodiesterase-mediated cAMP degradation: relevance to C6 glioma G1 phase progression.

  Neurotoxicology and teratology 20040101

• [Cross-hypersensitivity syndrome between antiepileptic drugs: report of a case].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20040101

• [A case of polymyalgia rheumatica with improved steroid-responsibility after discontinuing carbamazepine].

  No to shinkei = Brain and nerve 20040101

• Effects of valproic acid on longitudinal bone growth.

  Journal of child neurology 20040101

• Speech and language deterioration in benign rolandic epilepsy.

  Journal of child neurology 20040101

• Hypersensitivity to topiramate sprinkle capsules does not preclude the use of topiramate tablets.

  Paediatric drugs 20040101

• The diagnosis of Asperger's syndrome in an adult presenting with an index episode of mania by Ng et al.

  General hospital psychiatry 20040101

• Early cyclosporine treatment of incipient toxic epidermal necrolysis induced by concomitant use of lamotrigine and sodium valproate.

  Acta dermato-venereologica 20040101

• Allopurinol does not affect the anticonvulsant activity of carbamazepine and valproate in maximal electroshock-induced convulsions in mice.

  Polish journal of pharmacology 20040101

• Lithium and valproate protect against dextro-amphetamine induced brain choline concentration changes in bipolar disorder patients.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20040101

• Metabolism of a new antiepileptic drug, N-methyl-tetramethylcyclopropanecarboxamide, and anticonvulsant activity of its metabolites.

  Epilepsy research 20040101

• Valproic acid uptake by bovine brain microvessel endothelial cells: role of active efflux transport.

  Epilepsy research 20040101

• Assessment of seizure aggravation.

  CNS drugs 20040101

• Valproic acid for agitation in dementia.

  The Cochrane database of systematic reviews 20040101

• Valproic acid: an old drug newly discovered as inhibitor of histone deacetylases.

  Annals of hematology 20040101

• Extracorporeal management of valproic acid overdose: a large regional experience.

  Journal of nephrology 20040101

• [Drug-induced parkinson syndromes].

  Therapie 20040101

• Neuropsychiatric illness in a patient with cobalamin G disease, an inherited disorder of vitamin B12 metabolism.

  Harvard review of psychiatry 20040101

• New generation of valproic acid.

  Polish journal of pharmacology 20040101

• Strategies for preventing the recurrence of bipolar disorder.

  The Journal of clinical psychiatry 20040101

• Antiepileptic drugs in migraine prophylaxis: state of the art.

  La Clinica terapeutica 20040101

• Effects of the combination of valproate and ethosuximide on spike wave discharges in WAG/Rij rats.

  Epilepsy research 20040101

• The difficulties of diagnosing VPA-induced pancreatitis in children with severe motor and intellectual disabilities.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20040101

• Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons.

  The pharmacogenomics journal 20040101

• Risperidone does not affect steady-state pharmacokinetics of divalproex sodium in patients with bipolar disorder.

  Clinical pharmacokinetics 20040101

• Efficacy of sodium valproate in the treatment of photosensitive epilepsy (PSE) and the probable reasons for the persistence of occipital spikes.

  TheScientificWorldJournal 20040101

• Divalproex for the treatment of aggression associated with adolescent mania.

  Journal of child and adolescent psychopharmacology 20040101

• Successful use of hemodialysis in acute valproic acid intoxication.

  Journal of toxicology. Clinical toxicology 20040101

• [Biochemical basis of valproic acid toxicity: role of oxidative stress and effects of L-carnitine].

  Biomeditsinskaia khimiia 20040101

• The antidepressant effects of risperidone and olanzapine in bipolar disorder.

  The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20040101

• Valproate-induced hyperammonemic encephalopathy: imaging findings on diffusion-weighted MRI.

  European neurology 20040101

• [Valpromide, Valproic acid and removal of small intestine in the treatment of a chronic depression: a case report].

  L'Encephale 20040101

• Hippocampal volume measurement in older adults with bipolar disorder.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20040101

• [Treatment standard for bipolar disorders].

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20040101

• [Therapy of epilepsy: current strategy and tactics].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

• [Efficacy and safety of antiepileptic therapy in children (a comparative analysis of valproates and barbiturates)].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

• Employing pharmacologic treatment of bipolar disorder to greatest effect.

  The Journal of clinical psychiatry 20040101

• Recurrent mania associated with repeated brain injury.

  General hospital psychiatry 20040101

• [Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

• Brain neurosteroids in gender-related aggression induced by social isolation.

  Critical reviews in neurobiology 20040101

• Initiation of treatment and selection of antiepileptic drugs in childhood epilepsy.

  Epilepsia 20040101

• Effect of long-term therapy with sodium valproate on nail and serum trace element status in epileptic children.

  Biological trace element research 20040101

• Is a hypothermic effect of LY300164, valproate and phenobarbital evident in mice?

  Roczniki Akademii Medycznej w Bialymstoku (1995) 20040101

• [Mood disorders and XBP1].

  Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20040101

• [Bifocal atypical rolandic epilepsy with speech dyspraxia].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20040101

• [An acute pancreatitis in a child caused by Na-valproate].

  Acta chirurgica Iugoslavica 20040101

• Posterior reversible encephalopathy syndrome (PRES) in critically ill obstetric patients.

  Intensive care medicine 20031201

• Valproate modifies spontaneous excitation and inhibition at cortical synapses in vitro.

  Neuropharmacology 20031201

• Oxcarbazepine vs. valproate in the treatment of mood and schizoaffective disorders.

  The international journal of neuropsychopharmacology 20031201

• Sodium valproate in painful diabetic polyneuropathy.

  Acta neurologica Scandinavica 20031201

• Intravenous valproate associated with circulatory collapse.

  The Annals of pharmacotherapy 20031201

• Serum insulin and leptin levels and valproate-associated obesity.

  Epilepsia 20031201

• A re-evaluation of the role of antidepressants in the treatment of bipolar depression: data from the Stanley Foundation Bipolar Network.

  Bipolar disorders 20031201

• Mood-stabilizers: the archeology of the concept.

  Bipolar disorders 20031201

• 'Mood-stabilizers: the archeology of the concept'--by M Harris, S Chandran, N Chakraborty and D Healy: a commentary.

  Bipolar disorders 20031201

• Permeation across hydrated DPPC lipid bilayers: simulation of the titrable amphiphilic drug valproic acid.

  Biophysical journal 20031201

• Pharmacoepidemiologic investigation of a clonazepam-valproic acid interaction by mixed effect modeling using routine clinical pharmacokinetic data in Japanese patients.

  Journal of clinical pharmacy and therapeutics 20031201

• Exacerbation of mania secondary to right temporal lobe astrocytoma in a bipolar patient previously stabilized on valproate.

  Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology 20031201

• [Effects of chronic valproic acid sodium treatment and withdrawal on glutamate and glutamine release of C6 glioma cells].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20031201

• Lamotrigine monotherapy compared with carbamazepine, phenytoin, or valproate monotherapy in patients with epilepsy.

  Epilepsy & behavior : E&B 20031201

• Compliance and satisfaction with switching from an immediate-release to sustained-release formulation of valproate in people with epilepsy.

  Epilepsy & behavior : E&B 20031201

• Valproate-induced neural tube defects in folate-binding protein-2 (Folbp2) knockout mice.

  Birth defects research. Part A, Clinical and molecular teratology 20031201

• Combined therapy for migraine prevention? Clinical experience with a beta-blocker plus sodium valproate in 52 resistant migraine patients.

  Cephalalgia : an international journal of headache 20031201

• Evaluation of VPA dose and concentration effects on lamotrigine pharmacokinetics: implications for conversion to lamotrigine monotherapy.

  Epilepsy research 20031201

• Effect of valproate on hemostatic function in patients with traumatic brain injury.

  Epilepsy research 20031201

• Teratogenicity of valproate conjugates with anticonvulsant activity in mice.

  Epilepsy research 20031201

• Absence seizures in children.

  Clinical evidence 20031201

• Bipolar disorder.

  Clinical evidence 20031201

• Appropriateness of serum level determinations of antiepileptic drugs.

  Swiss medical weekly 20031122

• The influence of developmental periods of sodium valproate exposure on synaptic plasticity in the CA1 region of rat hippocampus.

  Neuroscience letters 20031120

• Sodium valproate induces apoptosis in the rat hepatoma cell line, FaO.

  Toxicology 20031105

• Effects of sodium valproate on synaptic plasticity in the CA1 region of rat hippocampus.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031101

• Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031101

• Valproate and GABAergic system effects.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20031101

• Pancreatitis in children.

  Journal of pediatric gastroenterology and nutrition 20031101

• Are drugs a risk factor of post-ERCP pancreatitis?

  Gastrointestinal endoscopy 20031101

• Valproic acid increases SMN levels in spinal muscular atrophy patient cells.

  Annals of neurology 20031101

• Once-a-day controlled-release dosage form of divalproex sodium II: development of a predictive in vitro drug release method.

  Journal of pharmaceutical sciences 20031101

• [A case of infantile epileptic apnea with congenital brain anomaly].

  No to hattatsu = Brain and development 20031101

• [Polycystic ovary syndrome and valproic acid].

  Revista de neurologia 20031101

• Valproate suppresses status epilepticus induced by 4-aminopyridine in CA1 hippocampus region.

  Epilepsia 20031101

• Hypoalbuminemia with valproic acid administration.

  Pediatric neurology 20031101

• Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system.

  Annals of the New York Academy of Sciences 20031101

• Structurally dissimilar antimanic agents modulate synaptic plasticity by regulating AMPA glutamate receptor subunit GluR1 synaptic expression.

  Annals of the New York Academy of Sciences 20031101

• Lithium regulates total and synaptic expression of the AMPA glutamate receptor GluR2 in vitro and in vivo.

  Annals of the New York Academy of Sciences 20031101

• Valproic acid-induced hearing loss and tinnitus.

  Internal medicine (Tokyo, Japan) 20031101

• Electrical amygdala kindling.

  Current protocols in pharmacology 20031101

• Nonconvulsive status epilepticus.

  Neurology 20031028

• Proton MRS reveals frontal lobe metabolite abnormalities in idiopathic generalized epilepsy.

  Neurology 20031014

• [Fetal valproate syndrome].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20031009

• Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20031008

• Properties of enteric coated sodium valproate pellets.

  International journal of pharmaceutics 20031002

• Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy.

  Human molecular genetics 20031001

• Mood stabilizers in hospitalized children with bipolar disorder: a retrospective review.

  Psychiatry and clinical neurosciences 20031001

• Effect of non-selective gamma-aminobutyric acid receptor stimulation on motor function of the lower oesophageal sphincter and gastro-oesophageal reflux in healthy human subjects.

  Alimentary pharmacology & therapeutics 20031001

• Somnambulism due to probable interaction of valproic acid and zolpidem.

  The Annals of pharmacotherapy 20031001

• Thrombocytopenia during valproic acid treatment in young patients with new-onset bipolar disorder.

  Journal of clinical psychopharmacology 20031001

• Dose-related pharmacokinetics and pharmacodynamics of valproate in the elderly.

  Journal of clinical psychopharmacology 20031001

• Landau-Kleffner syndrome responsive to levetiracetam.

  Epilepsy & behavior : E&B 20031001

• Clinical inquiries. What medication best prevents migraine in children?

  The Journal of family practice 20031001

• Yellow nail pigmentation following Depakote therapy.

  Journal of drugs in dermatology : JDD 20031001

• Retrospective study of hepatic enzyme elevations in children treated with olanzapine, divalproex, and their combination.

  Journal of the American Academy of Child and Adolescent Psychiatry 20031001

• [Ring chromosome 20, hypersensitivity to valproate and hyperammonemic encephalopathy].

  Revista de neurologia 20031001

• Adjunctive topiramate in bipolar II disorder.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20031001

• Design, synthesis and anticonvulsive activities of potential prodrugs linked by two-carbon chain.

  Archives of pharmacal research 20031001

• Partial seizure: an unusual cause of recurrent vomiting.

  International journal of clinical practice 20031001

• Divalproex sodium for the treatment of conduct disorder: a randomized controlled clinical trial.

  The Journal of clinical psychiatry 20031001

• Divalproex versus olanzapine in mania.

  The Journal of clinical psychiatry 20031001

• Worsening of psychosis after replacement of adjunctive valproate with topiramate in a schizophrenia patient.

  The Journal of clinical psychiatry 20031001

• Suicide risk in bipolar disorder during treatment with lithium and divalproex.

  JAMA 20030917

• Stuttering relieved by divalproex sodium.

  Neurology 20030909

• Regulation of phosphatidylglycerophosphate synthase by inositol in Saccharomyces cerevisiae is not at the level of PGS1 mRNA abundance.

  The Journal of biological chemistry 20030905

• Benign childhood epilepsy with centrotemporal spikes: a study of 50 Chinese children.

  Brain & development 20030901

• Absence seizures in patients with localization-related epilepsy.

  Brain & development 20030901

• A study of anticonvulsant medication on ovarian function in a group of women with epilepsy who have only ever taken one anticonvulsant compared with a group of women without epilepsy.

  Seizure 20030901

• Alterations in semen parameters in men with epilepsy treated with valproate or carbamazepine monotherapy.

  European journal of neurology 20030901

• Divalproex sodium extended-release for the prophylaxis of migraine headache.

  Expert opinion on pharmacotherapy 20030901

• The Australian registry of anti-epileptic drugs in pregnancy: experience after 30 months.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20030901

• Valproate disrupts regulation of inositol responsive genes and alters regulation of phospholipid biosynthesis.

  Molecular microbiology 20030901

• [Changes in GAT-3 and GABA-T mRNA expression of C6 glioma cells in response to a 2-week treatment with sodium valproate and withdrawal].

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030901

• [Multicenter study of occipital lobe epilepsy in childhood: clinical characteristics].

  No to hattatsu = Brain and development 20030901

• Management issues for women with epilepsy: neural tube defects and folic acid supplementation.

  Neurology 20030901

• Transdermal reverse iontophoresis of valproate: a noninvasive method for therapeutic drug monitoring.

  Pharmaceutical research 20030901

• Localized morphea: a rare adverse effect of valproic acid.

  Pediatric neurology 20030901

• Intravenous sodium valproate in status epilepticus.

  Neurology India 20030901

• Possible involvement of the ERK signaling cascade in bipolar disorder: behavioral leads from the study of mutant mice.

  Drug news & perspectives 20030901

• Adding topiramate to valproate therapy may cause reversible hepatic failure.

  Epileptic disorders : international epilepsy journal with videotape 20030901

• [Fetal valproate syndrome].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20030828

• EDTA-dependent pseudothrombocytopenia induced by valproic acid.

  Neurology 20030826

• Older patients are eligible for trial of lithium and valproate.

  BMJ (Clinical research ed.) 20030816

• The role of the extracellular signal-regulated kinase signaling pathway in mood modulation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20030813

• Is the interaction between felbamate and valproate against seizures induced by 4-aminopyridine and pentylenetetrazole in mice beneficial?

  Pharmacological research 20030801

• Two case studies of hypothermia induced by an increased dosage of zotepine in a combination therapy.

  Psychiatry and clinical neurosciences 20030801

• Valproate induces reversible factor XIII deficiency with risk of perioperative bleeding.

  Acta neurologica Scandinavica 20030801

• Direct observation of 3-keto-valproate in urine by 2D-NMR spectroscopy.

  Clinica chimica acta; international journal of clinical chemistry 20030801

• Combination lithium and divalproex sodium in pediatric bipolarity.

  Journal of the American Academy of Child and Adolescent Psychiatry 20030801

• Valproate inhibits the conversion of testosterone to estradiol and acts as an apoptotic agent in growing porcine ovarian follicular cells.

  Epilepsia 20030801

• Effects of chronic lithium and sodium valproate on concentrations of brain amino acids.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20030801

• Fatal sodium valproate-induced hypersensitivity syndrome with lichenoid dermatitis and fulminant hepatitis.

  Journal of the American Academy of Dermatology 20030801

• Antipsychotic-induced weight gain: bipolar disorder and leptin.

  Journal of clinical psychopharmacology 20030801

• Adjunctive quetiapine in bipolar patients partially responsive to lithium or valproate.

  Progress in neuro-psychopharmacology & biological psychiatry 20030801

• Divalproex monotherapy in the treatment of bipolar offspring with mood and behavioral disorders and at least mild affective symptoms.

  The Journal of clinical psychiatry 20030801

• Patent ductus arteriosus in fetal valproate syndrome.

  Indian journal of pediatrics 20030801

• Valproic acid-induced eosinophilic pleural effusion.

  Southern medical journal 20030801

• [Influence of valproic acid (depakine I.V.) on human placenta metabolism--experimental model].

  Ginekologia polska 20030801

• Valproate induces replication-independent active DNA demethylation.

  The Journal of biological chemistry 20030725

• Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus.

  Neuroscience letters 20030717

• Search for a common mechanism of mood stabilizers.

  Biochemical pharmacology 20030715

• Effect of valproic acid on the urinary metabolic profile of a patient with succinic semialdehyde dehydrogenase deficiency.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030715

• Maintenance efficacy of divalproex in the prevention of bipolar depression.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030701

• Valproic acid inhibits substance P-induced activation of protein kinase C epsilon and expression of the substance P receptor.

  Journal of neurochemistry 20030701

• Valproic acid increases the stimulatory effect of estrogens on proliferation of human endometrial adenocarcinoma cells.

  Endocrinology 20030701

• Risperidone in acute and continuation treatment of mania.

  International clinical psychopharmacology 20030701

• Lamotrigine in adolescent mood disorders.

  Journal of the American Academy of Child and Adolescent Psychiatry 20030701

• Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: a 47-week study.

  The American journal of psychiatry 20030701

• Pilot comparison of extended-release and standard preparations of divalproex sodium in patients with bipolar and schizoaffective disorders.

  The American journal of psychiatry 20030701

• The histone deacetylase inhibitor valproic acid selectively induces proteasomal degradation of HDAC2.

  The EMBO journal 20030701

• Septo-optic dysplasia plus.

  The Lancet. Neurology 20030701

• Successful pregnancy in a patient with hyperoxaluria and combined liver and renal transplant.

  Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20030701

• The safety and early efficacy of oral-loaded divalproex versus standard-titration divalproex, lithium, olanzapine, and placebo in the treatment of acute mania associated with bipolar disorder.

  The Journal of clinical psychiatry 20030701

• Diabetic ketoacidosis in a patient treated with olanzapine, valproic acid, and venlafaxine.

  Southern medical journal 20030701

• Neurotoxicity following addition of intravenous valproate to lamotrigine therapy.

  Neurology 20030624

• Effects of valproic acid on an animal model of tardive dyskinesia.

  Behavioural brain research 20030616

• Valproic acid enhances axonal regeneration and recovery of motor function after sciatic nerve axotomy in adult rats.

  Brain research 20030613

• Divalproex in the treatment of impulsive aggression: efficacy in cluster B personality disorders.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030601

• Valproyl-CoA and esterified valproic acid are not found in brains of rats treated with valproic acid, but the brain concentrations of CoA and acetyl-CoA are altered.

  Neurochemical research 20030601

• The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats.

  Free radical biology & medicine 20030601

• Once-a-day controlled-release dosage form of divalproex sodium I: formulation design and in vitro/in vivo investigations.

  Journal of pharmaceutical sciences 20030601

• Intravenous sodium valproate versus prochlorperazine for the emergency department treatment of acute migraine headaches: a prospective, randomized, double-blind trial.

  Annals of emergency medicine 20030601

• Unbound valproate fraction in plasma and subcutaneous microdialysate in steady state and after a single dose in humans.

  Therapeutic drug monitoring 20030601

• A study of EEG and epilepsy profile in Wolf-Hirschhorn syndrome and considerations regarding its correlation with other chromosomal disorders.

  Brain & development 20030601

• Valproic acid-induced neutropenia.

  The Annals of pharmacotherapy 20030601

• Nonketotic hyperosmolar syndrome from olanzapine, lithium, and valproic acid cotreatment.

  The Annals of pharmacotherapy 20030601

• Valproate.

  Bipolar disorders 20030601

• Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder.

  Bipolar disorders 20030601

• Electroencephalogram changes and its improvement with sodium valproate in a patient with electrocution-induced chronic mania.

  Bipolar disorders 20030601

• Valproic acid fails to induce polycystic ovary syndrome in female rats.

  Progress in neuro-psychopharmacology & biological psychiatry 20030601

• Combination pharmacotherapy in children and adolescents with bipolar disorder.

  Biological psychiatry 20030601

• Endocrine and metabolic responses to long-term monotherapy with the antiepileptic drug valproate in the normally cycling rhesus monkey.

  The Journal of clinical endocrinology and metabolism 20030601

• Gabapentin in geriatric mania.

  Journal of geriatric psychiatry and neurology 20030601

• Anticonvulsant activity, teratogenicity and pharmacokinetics of novel valproyltaurinamide derivatives in mice.

  British journal of pharmacology 20030601

• 'Outer-directed irritability': a distinct mood syndrome in explosive youth with a disruptive behavior disorder?

  The Journal of clinical psychiatry 20030601

• HPLC determination of valproic acid in human serum.

  Die Pharmazie 20030601

• Determination of valproic acid (2-propylpentanoic acid) in human plasma by capillary electrophoresis with indirect UV detection.

  Electrophoresis 20030601

• Levetiracetam in the treatment of rapid cycling bipolar disorder.

  Journal of psychopharmacology (Oxford, England) 20030601

• Out-of-hospital management of benzodiazepine-resistant status epilepticus in a child with Wolf-Hirschhorn syndrome.

  Epileptic disorders : international epilepsy journal with videotape 20030601

• Acute psychosis associated with levetiracetam.

  Epileptic disorders : international epilepsy journal with videotape 20030601

• Reflex myoclonic epilepsy in infancy: a benign age-dependent idiopathic startle epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20030601

• Lack of effect of mood stabilizers or neuroleptics on GSK-3 protein levels and GSK-3 activity.

  The international journal of neuropsychopharmacology 20030601

• Suspected lamotrigine-induced toxic epidermal necrolysis.

  Acta neurologica Belgica 20030601

• An unusual case of benign reflex myoclonic epilepsy of infancy.

  Neuropediatrics 20030601

• Ultrastructure of astrocytes in the cortex of the hippocampal gyrus and in the neocortex of the temporal lobe in experimental valproate encephalopathy and after valproate withdrawal.

  International journal of experimental pathology 20030601

• Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention?

  Molecular interventions 20030601

• [Treatment of acute bipolar disorder. Intriguing balancing act between mania and depression].

  MMW Fortschritte der Medizin 20030526

• [Persisting deficits after severe depression].

  MMW Fortschritte der Medizin 20030526

• [Fast control of manic or mixed episodes. Atypical neuroleptics for bipolar patients].

  MMW Fortschritte der Medizin 20030526

• [Long-term therapy with intuition].

  MMW Fortschritte der Medizin 20030526

• The anticonvulsant valproate increases the turnover rate of gamma-aminobutyric acid transporters.

  The Journal of biological chemistry 20030516

• Sp family of transcription factors is involved in valproic acid-induced expression of Galphai2.

  The Journal of biological chemistry 20030516

• Differential cognitive and behavioral effects of topiramate and valproate.

  Neurology 20030513

• Valproic acid, a mood stabilizer and anticonvulsant, protects rat cerebral cortical neurons from spontaneous cell death: a role of histone deacetylase inhibition.

  FEBS letters 20030508

• Gas chromatographic determination of novel valproyl taurinamide derivatives in mouse and dog plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505

• Changing prescription patterns for lithium and valproic acid in old age: shifting practice without evidence.

  BMJ (Clinical research ed.) 20030503

• The effects of chronic treatment with the mood stabilizers valproic acid and lithium on corticotropin-releasing factor neuronal systems.

  The Journal of pharmacology and experimental therapeutics 20030501

• Volume-selective 1H MR spectroscopy for in vivo detection of valproate in patients with epilepsy.

  Neuroradiology 20030501

• Valproic acid down-regulates the conversion of arachidonic acid to eicosanoids via cyclooxygenase-1 and -2 in rat brain.

  Journal of neurochemistry 20030501

• Valproic acid for the treatment of social anxiety disorder.

  International clinical psychopharmacology 20030501

• [Effects of valproate on sexual development].

  Anales de pediatria (Barcelona, Spain : 2003) 20030501

• Chronic lithium and sodium valproate both decrease the concentration of myoinositol and increase the concentration of inositol monophosphates in rat brain.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20030501

• Valporic acid and prion proteins.

  Annals of neurology 20030501

• The effect of valproic acid on drug and steroid glucuronidation by expressed human UDP-glucuronosyltransferases.

  Biochemical pharmacology 20030501

• Effects of valproic acid, carbamazepine, and phenobarbitone on the fatty acid composition of erythrocyte membranes in children.

  Epilepsia 20030501

• Safety and efficacy of intravenous valproate in pediatric status epilepticus and acute repetitive seizures.

  Epilepsia 20030501

• The management of idiopathic olfactory hallucinations: a study of two patients.

  The Laryngoscope 20030501

• Congenital nasolacrimal duct obstruction requiring external dacryocystorhinostomies in a child with foetal valproate syndrome.

  Eye (London, England) 20030501

• Experimental anxiety and antiepileptics: the effects of valproate and vigabatrin in the mirrored chamber test.

  Methods and findings in experimental and clinical pharmacology 20030501

• Higher androgens and weight gain with valproate compared with lamotrigine for epilepsy.

  Epilepsy research 20030501

• Lamotrigine and valproate: efficacy of co-administration in a pediatric population.

  Pediatric neurology 20030501

• Reversible altered consciousness with brain atrophy caused by valproic acid.

  Pediatric neurology 20030501

• Identification and quantitation of xenobiotics by 1H NMR spectroscopy in poisoning cases.

  Forensic science international 20030423

• Safety and efficacy of switching psychiatric patients from a delayed-release to an extended-release formulation of divalproex sodium.

  Journal of clinical psychopharmacology 20030401

• Antidepressant properties of anticonvulsant drugs for bipolar disorder.

  Journal of clinical psychopharmacology 20030401

• New CNS-active drugs which are second-generation valproic acid: can they lead to the development of a magic bullet?

  Current opinion in neurology 20030401

• Immunoglobulins in children with epilepsy: the Dutch Study of Epilepsy in Childhood.

  Clinical and experimental immunology 20030401

• Therapeutic monitoring of digoxin and antiepileptic drugs in Egypt and Saudi Arabia.

  Therapeutic drug monitoring 20030401

• Lithium, but not valproate, induces the serine/threonine phosphatase activity of protein phosphatase 2A in the rat brain, without affecting its expression.

  Journal of neural transmission (Vienna, Austria : 1996) 20030401

• Enhancing treatment of bipolar disorder using the patient's belief system.

  The Annals of pharmacotherapy 20030401

• [Remission of polycystic ovary syndrome associated with valproic acid in an epileptic female].

  Revista de neurologia 20030401

• Acute akinetic crisis with marked cognitive impairment due to Valproate treatment.

  International journal of geriatric psychiatry 20030401

• Valproate overdose: a comparative cohort study of self poisonings.

  British journal of clinical pharmacology 20030401

• Antiepileptic drug hypersensitivity syndrome in a patient treated with valproate.

  British journal of clinical pharmacology 20030401

• New management strategies in the treatment of status epilepticus.

  Mayo Clinic proceedings 20030401

• Hypouricemia in severely disabled children: influence of valproic acid and bed-ridden state.

  Brain & development 20030401

• A case of nonconvulsive status epilepticus associated with focal cortical dysplasia.

  Brain & development 20030401

• The new patient with a first seizure.

  Australian family physician 20030401

• Topiramate protects against glutamate- and kainate-induced neurotoxicity in primary neuronal-astroglial cultures.

  Epilepsy research 20030401

• Do epileptic children treated with valproate have a risk of excessive weight gain?

  Journal of child neurology 20030401

• EEG does not predict response to valproate treatment of aggression in patients with borderline and antisocial personality disorders.

  Clinical EEG (electroencephalography) 20030401

• Rapid infusion of sodium valproate in acutely ill children.

  Pediatric neurology 20030401

• Low dose of sodium divalproate for the treatment of migraine.

  MedGenMed : Medscape general medicine 20030312

• Electrophysiological, neurochemical and regional effects of levetiracetam in the rat pilocarpine model of temporal lobe epilepsy.

  Seizure 20030301

• Effects of valproate and carbamazepine on serum levels of homocysteine, vitamin B12, and folic acid.

  Brain & development 20030301

• Chronic treatment with lithium, but not sodium valproate, increases cortical N-acetyl-aspartate concentrations in euthymic bipolar patients.

  International clinical psychopharmacology 20030301

• Migraine preventive medication reduces resource utilization.

  Headache 20030301

• Topiramate, carbamazepine and valproate monotherapy: double-blind comparison in newly diagnosed epilepsy.

  Acta neurologica Scandinavica 20030301

• Effects of age and polytherapy, risk factors of valproic acid (VPA) hepatotoxicity, on the excretion of thiol conjugates of (E)-2,4-diene VPA in people with epilepsy taking VPA.

  Epilepsia 20030301

• [Reflex myoclonic epilepsy in infancy: a new reflex epilepsy syndrome or a variant of benign myoclonic epilepsy in infancy].

  Revista de neurologia 20030301

• [The value of topiramate used with conventional schemes as an adjunctive therapy in the treatment of Lennox-Gastaut syndrome].

  Revista de neurologia 20030301

• Sodium valproate and measles virus replication.

  European journal of pediatrics 20030301

• Evaluation of therapeutic drug monitoring of antiepileptic drugs.

  International journal of clinical pharmacology and therapeutics 20030301

• Effects of dextroamphetamine, lithium chloride, sodium valproate and carbamazepine on intraplatelet Ca2+ levels.

  Journal of psychiatry & neuroscience : JPN 20030301

• Treating acute mania.

  The Journal of family practice 20030301

• Treating bipolar depression.

  The Journal of family practice 20030301

• Long-term therapy of bipolar illness.

  The Journal of family practice 20030301

• Optimal dosing of medications (in bipolar disorder).

  The Journal of family practice 20030301

• Effects of valproate, phenytoin, and zonisamide on clonic and tonic seizures induced by acute and repeated exposure of mice to flurothyl.

  Physiology & behavior 20030301

• Amelioration of sodium valproate-induced neural tube defects in mouse fetuses by maternal folic acid supplementation during gestation.

  Congenital anomalies 20030301

• Uptake of GABA and activity of GABA-transaminase in platelets from epileptic patients.

  Epilepsy research 20030301

• Divalproex sodium versus olanzapine in the treatment of acute mania in bipolar disorder: health-related quality of life and medical cost outcomes.

  The Journal of clinical psychiatry 20030301

• Anticonvulsant valproic acid inhibits cardiomyocyte differentiation of embryonic stem cells by increasing intracellular levels of reactive oxygen species.

  Birth defects research. Part A, Clinical and molecular teratology 20030301

• Fasting serum insulin and lipid levels in men with epilepsy.

  Neurology 20030225

• Major malformations in offspring of women with epilepsy.

  Neurology 20030225

• Valproate attenuates hyperactive and perseverative behaviors in mutant mice with a dysregulated dopamine system.

  Biological psychiatry 20030215

• [A child with peculiar movements: Sydenham chorea].

  Nederlands tijdschrift voor geneeskunde 20030208

• The role of anticonvulsants in preventive migraine therapy.

  Current pain and headache reports 20030201

• Valproate-associated reproductive and metabolic abnormalities: are epileptic women at greater risk than bipolar women?

  Progress in neuro-psychopharmacology & biological psychiatry 20030201

• Levetiracetam, a new antiepileptic agent: lack of in vitro and in vivo pharmacokinetic interaction with valproic acid.

  Epilepsia 20030201

• Valproate-induced hyperammonemic encephalopathy.

  Epilepsia 20030201

• Mood stabilisers plus risperidone or placebo in the treatment of acute mania. International, double-blind, randomised controlled trial.

  The British journal of psychiatry : the journal of mental science 20030201

• Valproate unbound fraction and distribution volume following rapid infusions in patients with epilepsy.

  Epilepsy research 20030201

• Oral/intravenous maintenance dosing of valproate following intravenous loading: a simulation.

  Epilepsy research 20030201

• Characterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.

  British journal of pharmacology 20030201

• Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity.

  Epilepsy & behavior : E&B 20030201

• Comparison of lamotrigine and valproate with respect to quality of life.

  Epilepsy & behavior : E&B 20030201

• Re: 'Cades disease' and beyond.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20030201

• Valproate, bipolar disorder and polycystic ovarian syndrome.

  Bipolar disorders 20030201

• [GEFS + syndrome: phenotypic variations from the newborn to the adult in a large French pedigree].

  Revue neurologique 20030201

• Pancreatic pseudocyst caused by valproic acid: case report and review of the literature.

  European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20030201

• Lamotrigine versus valproate monotherapy-associated weight change in adolescents with epilepsy: results from a post hoc analysis of a randomized, double-blind clinical trial.

  Journal of child neurology 20030201

• Valproic acid-associated weight gain in older children and teens with epilepsy.

  Pediatric neurology 20030201

• Acute pancreatitis in children from Valproic acid: case series and review.

  Pediatric neurology 20030201

• Synthesis of [(18)O(2)]valproic acid and its use as an internal standard for the quantitative measurement by gas chromatography-electron ionization mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030125

• Valproic acid overdose: a case report and review of therapy.

  MedGenMed : Medscape general medicine 20030114

• Valproic acid and lamotrigine treatment during pregnancy. The risk of chromosomal abnormality.

  Mutation research 20030110

• Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.

  Neuroscience letters 20030102

• Amino acid conjugates: metabolites of 2-propylpentanoic acid (valproic acid) in epileptic patients.

  Drug metabolism and disposition: the biological fate of chemicals 20030101

• Effect of divalproex combined with olanzapine or risperidone in patients with an acute exacerbation of schizophrenia.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101

• Valproic acid and risperidone: a drug interaction?

  Journal of the American Academy of Child and Adolescent Psychiatry 20030101

• Valproic Acid and risperidone.

  Journal of the American Academy of Child and Adolescent Psychiatry 20030101

• The safety of valproic acid use for patients with hepatitis C infection.

  The American journal of psychiatry 20030101

• Lupus-like syndrome and vasculitis induced by valpromide.

  The Journal of rheumatology 20030101

• Lithium and valproate decrease the membrane phosphatidylinositol/phosphatidylcholine ratio.

  Molecular microbiology 20030101

• Visual hallucinations associated with zonisamide.

  Pharmacotherapy 20030101

• Drug treatment of epilepsy in elderly people: focus on valproic Acid.

  Drugs & aging 20030101

• Valproate for acute mood episodes in bipolar disorder.

  The Cochrane database of systematic reviews 20030101

• Safety and tolerance of rapidly infused Depacon. A randomized trial in subjects with epilepsy.

  Epilepsy research 20030101

• Valproate inhibits oxidative damage to lipid and protein in primary cultured rat cerebrocortical cells.

  Neuroscience 20030101

• Hemodialysis versus continuous veno-venous hemodiafiltration in the management of severe valproate overdose.

  Clinical nephrology 20030101

• [The Charles Bonnet syndrome: a case report and a brief review].

  Actas espanolas de psiquiatria 20030101

• [Favorable course of Lance-Adams postanoxic action myoclonus].

  Revue neurologique 20030101

• Suggestions for improving intimacy in couples in which one partner has attention-deficit/ hyperactivity disorder.

  Journal of sex & marital therapy 20030101

• New approaches in managing bipolar depression.

  The Journal of clinical psychiatry 20030101

• [Case no 3. MELAS syndrome].

  Journal de radiologie 20030101

• Attenuation of N-methyl-D-aspartate-mediated cytoplasmic vacuolization in primary rat hippocampal neurons by mood stabilizers.

  Neuroscience 20030101

• Carnitine level in Chinese epileptic patients taking sodium valproate.

  Pediatric neurology 20030101

• Favorable outcome of epileptic blindness in children.

  Journal of child neurology 20030101

• Treatment of agitation in bipolar disorder across the life cycle.

  The Journal of clinical psychiatry 20030101

• The modulation of irinotecan-induced diarrhoea and pharmacokinetics by three different classes of pharmacologic agents.

  Oncology reports 20030101

• Increase of fetal hemoglobin synthesis indicating differentiation induction in children receiving valproic acid.

  Pediatric hematology and oncology 20030101

• Acute antimanic efficacy and safety of intravenous valproate loading therapy: an open-label study.

  Neuropsychobiology 20030101

• The use of mood stabilizers as plasticity enhancers in the treatment of neuropsychiatric disorders.

  The Journal of clinical psychiatry 20030101

• Drug interactions of lithium and other antimanic/mood-stabilizing medications.

  The Journal of clinical psychiatry 20030101

• Successful antimanic treatment and mood stabilization with lamotrigine, clozapine, and valproate in a bipolar patient after lithium-induced cerebellar deterioration. A case report.

  Pharmacopsychiatry 20030101

• Acute management of seizures in the syndromes of idiopathic generalized epilepsies.

  Epilepsia 20030101

• Chronic management of seizures in the syndromes of idiopathic generalized epilepsy.

  Epilepsia 20030101

• An assessment of the in vitro antimicrobial effects of two antiepileptic drugs--sodium valproate and phenytoin.

  Antonie van Leeuwenhoek 20030101

• Anticonvulsant hypersensitivity syndrome: report of 2 cases from Kuwait.

  Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20030101

• Polycystic ovary syndrome and epilepsy: a review of the evidence.

  Drugs 20030101

• [Yawning and temporal lobe epilepsy].

  Medicina 20030101

• Treating selective serotonin reuptake inhibitor-induced behavioral activation with valproate.

  Journal of child and adolescent psychopharmacology 20030101

• Antiepileptic drug-induced pharmacodynamic aggravation of seizures: does valproate have a lower potential?

  CNS drugs 20030101

• [Influence of ivadal and depakene chrono on sleep structure in patients with epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101

• [Clinical efficacy and tolerability of topamax in combined therapy of epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101

• Great progress in diagnosis and treatment of dementia.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20030101

• Valproate therapy for agitation in dementia: open-label extension of a double-blind trial.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20030101

• [Hyperammonemic encephalopathy associated with valproate acid].

  Neurologia (Barcelona, Spain) 20030101

• Valproate: past, present, and future.

  CNS drug reviews 20030101

• The vegetarian who ate a sausage with curry sauce.

  The Lancet. Neurology 20030101

• Enhancement of circulatory antioxidants by alpha-ketoglutarate during sodium valproate treatment in Wistar rats.

  Polish journal of pharmacology 20030101

• Dementia management: regulations, rules, and research.

  Journal of the American Medical Directors Association 20030101

• A putative relationship between valproic acid and polycystic ovarian syndrome: implications for treatment of women with seizure and bipolar disorders.

  Harvard review of psychiatry 20030101

• [Manic phase (manic episode)].

  Ryoikibetsu shokogun shirizu 20030101

• [Mechanism and clinical effects of drugs for mood disorder].

  Ryoikibetsu shokogun shirizu 20030101

• [Pharmacokinetics and drug interaction of antidepressants and anti-manic drugs].

  Ryoikibetsu shokogun shirizu 20030101

• [Antidepressant induced rapid cycling].

  Ryoikibetsu shokogun shirizu 20030101

• Carnitine transport: pathophysiology and metabolism of known molecular defects.

  Journal of inherited metabolic disease 20030101

• Laughing headache: a novel type of triggered headache with response to divalproex sodium.

  Headache 20030101

• Ammonia induced encephalopathy from valproic acid in a bipolar patient: case report.

  International journal of psychiatry in medicine 20030101

• Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents.

  The Cochrane database of systematic reviews 20030101

• 'My Father Did This to Me!' the psychodynamic treatment of an angry, sad, and violent young man.

  Harvard review of psychiatry 20030101

• Valproic acid modulates islet cell insulin secretion: a possible mechanism of weight gain in epilepsy patients.

  Epilepsy research 20030101

• Pleural fluid eosinophilia with combined pharmacotherapy.

  Psychosomatics 20030101

• [Pharmacokinetic interaction between valproic acid and carbapenem-like antibiotics: a discussion of three cases].

  Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20030101

• Influence of vigabatrin, a novel antiepileptic drug, on the anticonvulsant activity of conventional antiepileptics in pentetrazole-induced seizures in mice.

  Polish journal of pharmacology 20030101

• Epilepsy: from consensus to daily practice.

  Acta neurologica Scandinavica. Supplementum 20030101

• Prevention of epilepsy after head trauma: do we need new drugs or a new approach?

  Epilepsia 20030101

• Drug-induced pseudotumor cerebri.

  Clinical neuropharmacology 20030101

• Some antiepileptic compounds impair learning by rats in a Morris water maze.

  Integrative physiological and behavioral science : the official journal of the Pavlovian Society 20030101

• Evidence-based mental health use of anticonvulsants during pregnancy.

  Psychopharmacology bulletin 20030101

• [Electroclinical characteristics of Landau-Kleffner syndrome].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101

• [The use of depakene and depakene-chrono in idiopathic generalized epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101

• Multiple congenital malformations including generalized hypertrichosis with gum hypertrophy in a child exposed to valproic acid in utero.

  Genetic counseling (Geneva, Switzerland) 20030101

• Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes.

  The pharmacogenomics journal 20030101

• The history of valproate in clinical neuroscience.

  Psychopharmacology bulletin 20030101

• Pharmacology of valproate.

  Psychopharmacology bulletin 20030101

• Pharmacokinetics, drug interactions, and tolerability of valproate.

  Psychopharmacology bulletin 20030101

• [Organic manic disorder].

  Ryoikibetsu shokogun shirizu 20030101

• [Organic bipolar disorder].

  Ryoikibetsu shokogun shirizu 20030101

• [Organic solvent-related mental disorders].

  Ryoikibetsu shokogun shirizu 20030101

• [Anticonvulsants in preventive therapy of migraine].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101

• [Experimental validation of regeneration therapy in hepatitis caused by toxic medication].

  Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20030101

• Efficiency of high-flux hemodialysis in the treatment of valproic acid intoxication.

  Journal of toxicology. Clinical toxicology 20030101

• Carnitine.

  Journal of toxicology. Clinical toxicology 20030101

• Role of carnitine in valproic acid toxicity.

  Journal of toxicology. Clinical toxicology 20030101

• Effect of valproic acid on levels of GABA and glutamic acid in pentylenetetrazole-damaged rat brain.

  Proceedings of the Western Pharmacology Society 20030101

• Effect of some convulsants on the protective activity of loreclezole and its combinations with valproate or clonazepam in amygdala-kindled rats.

  Polish journal of pharmacology 20030101

• Influence of SIB 1893, a selective mGluR5 receptor antagonist, on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy.

  Polish journal of pharmacology 20030101

• Nicotine diminishes anticonvulsant activity of antiepileptic drugs in mice.

  Polish journal of pharmacology 20030101

• Detection and quantitation of xenobiotics in biological fluids by 1H NMR spectroscopy.

  Journal of toxicology. Clinical toxicology 20030101

• Axial skeletal and Hox expression domain alterations induced by retinoic acid, valproic acid, and bromoxynil during murine development.

  Journal of biochemical and molecular toxicology 20030101

• Endoscopic ultrasound localization of a solitary insulinoma of pancreatic tail misdiagnosed as epilepsy: case report.

  Abdominal imaging 20030101

• [Efficacy of depakine chrono and lithium combination in the treatment of manic states].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101

• Treatment of agitation using Depakote: a patient with dementia.

  Psychiatry 20030101

• Clinical case presentation: therapeutic challenges in adolescent-onset bipolar disorder.

  Journal of child and adolescent psychopharmacology 20030101

• Long-term outcome with divalproex in children and adolescents with bipolar disorder.

  Journal of child and adolescent psychopharmacology 20030101

• Divalproex and epilepsy.

  Psychopharmacology bulletin 20030101

• The efficacy of divalproex for partial epilepsies.

  Psychopharmacology bulletin 20030101

• Divalproex in the treatment of bipolar disorder.

  Psychopharmacology bulletin 20030101

• Schizophrenia and valproate.

  Psychopharmacology bulletin 20030101

• The use of divalproex in the treatment of addictive disorders.

  Psychopharmacology bulletin 20030101

• Divalproex in the treatment of migraine.

  Psychopharmacology bulletin 20030101

• Valproate use in neuropsychiatric disorders in the elderly.

  Psychopharmacology bulletin 20030101

• [Modulating effect of anticonvulsive agents on Ca2+ dependent membrane fusion in cell-free model of neurosecretion].

  Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101

• [The effect of antiepileptic drug therapy on antioxidant enzyme activity and serum lipid peroxidation in young patients with epilepsy].

  Neurologia i neurochirurgia polska 20030101

• Pharmaceutical drug overdose case reports. From the World Literature.

  Toxicological reviews 20030101

• Anticonvulsant valproate reduces seizure-susceptibility in mutant Drosophila.

  Brain research 20021220

• Cortical functional abnormality assessed by auditory-evoked magnetic fields and therapeutic approach in patients with chronic dizziness.

  Brain research 20021213

• Mood stabilizers in Alzheimer's disease: symptomatic and neuroprotective rationales.

  Advanced drug delivery reviews 20021207

• Predictors of ovulatory failure in women with epilepsy.

  Annals of neurology 20021201

• Valproate-induced hyperammonaemia.

  Journal of clinical psychopharmacology 20021201

• Surveillance for fatal suspected adverse drug reactions in the UK.

  Archives of disease in childhood 20021201

• Thoughts on Aldenkamp et al.'s article.

  Epilepsia 20021201

• Delayed absorption of valproic acid, resulting in coma.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20021201

• Outcome of pregnancy in women attending an outpatient epilepsy clinic: adverse features associated with higher doses of sodium valproate.

  Seizure 20021201

• Population pharmacokinetics of intravenous valproic acid in Korean patients.

  Journal of clinical pharmacy and therapeutics 20021201

• Regulation of Akt and glycogen synthase kinase-3 beta phosphorylation by sodium valproate and lithium.

  Neuropharmacology 20021201

• A comparison of the efficacy, safety, and tolerability of divalproex sodium and olanzapine in the treatment of bipolar disorder.

  The Journal of clinical psychiatry 20021201

• Neuroprotective properties of valproate: potential benefit for AD and tauopathies.

  Journal of molecular neuroscience : MN 20021201

• Role of carnitine and fatty acid oxidation and its defects in infantile epilepsy.

  Journal of child neurology 20021201

• Long-term neuropsychological follow-up and nosological considerations in five patients with continuous spikes and waves during slow sleep.

  Epileptic disorders : international epilepsy journal with videotape 20021201

• Valproate-induced hyperammonemic encephalopathy.

  Metabolic brain disease 20021201

• Absence seizures in children.

  Clinical evidence 20021201

• Aggregate data meta-analysis with time-to-event outcomes.

  Statistics in medicine 20021130

• Valproate prevents the induction and the expression of MK-801 sensitization.

  Brain research 20021108

• Sodium valproate in the management of painful neuropathy in type 2 diabetes - a randomized placebo controlled study.

  Acta neurologica Scandinavica 20021101

• Self-reported adherence to treatment with mood stabilizers, plasma levels, and psychiatric hospitalization.

  The American journal of psychiatry 20021101

• Acute pancreatitis coincident with valproate use: a critical review.

  Epilepsia 20021101

• Effects of short-term administration of valproate on serotonin-1A and dopamine receptor function in healthy human subjects.

  Journal of psychiatry & neuroscience : JPN 20021101

• [Long-term efficacy and tolerance of stiripentaol in severe myoclonic epilepsy of infancy (Dravet's syndrome)].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20021101

• Successful treatment of Ohtahara syndrome with chloral hydrate.

  Pediatric neurology 20021101

• Initial triple therapy of acute mania, adding lithium and valproate to neuroleptics.

  Pharmacopsychiatry 20021101

• Antiepileptic drugs in schizophrenia: a review.

  European psychiatry : the journal of the Association of European Psychiatrists 20021101

• No effect of long-term valproate therapy on thyroid and parathyroid functions in children.

  The International journal of neuroscience 20021101

• Inhibition of tubulin assembly and covalent binding to microtubular protein by valproic acid glucuronide in vitro.

  Life sciences 20021018

• Synergistic interaction between valproate and lamotrigine against seizures induced by 4-aminopyridine and pentylenetetrazole in mice.

  European journal of pharmacology 20021018

• Teratogen-induced limb defects.

  American journal of medical genetics 20021015

• Reverse phase HPLC for polar lipids. Simple and selective HPLC procedures for analysis of phospholipid-based derivatives of valproic acid and various non-steroidal anti-inflammatory drugs.

  Journal of pharmaceutical and biomedical analysis 20021015

• Drug treatment of conduct disorder in young people.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20021001

• Conventional anticonvulsant drugs in the guinea pig kindling model of partial seizures: effects of acute phenobarbital, valproate, and ethosuximide.

  Experimental brain research 20021001

• Clinical expression and EEG features of patients with juvenile myoclonic epilepsy (JME) from North India.

  Seizure 20021001

• Letter to the editor. Discordant twins for neural tube defect on treatment with sodium valproate.

  Seizure 20021001

• Sudden unexplained death in epilepsy (SUDEP) following previous seizure-related pulmonary oedema: case report and review of possible preventative treatment.

  Seizure 20021001

• Divalproex sodium therapy in elderly with dementia-related agitation.

  The Annals of pharmacotherapy 20021001

• Valproic acid treatment results in increased accumulation of prion proteins.

  Annals of neurology 20021001

• Treatment of bipolar I rapid cycling patients during dysphoric mania with olanzapine.

  Journal of clinical psychopharmacology 20021001

• Combination of olanzapine and divalproex for agitation in individuals with profound mental retardation.

  Journal of clinical psychopharmacology 20021001

• Sexual side effects associated with valproate.

  Journal of clinical psychopharmacology 20021001

• Does lamotrigine influence valproate concentrations?

  Therapeutic drug monitoring 20021001

• An in ovo chicken model to study the systemic and localized teratogenic effects of valproic acid.

  Teratology 20021001

• Increased monoamine concentration in the brain and blood of fetal thalidomide- and valproic acid-exposed rat: putative animal models for autism.

  Pediatric research 20021001

• Antiproliferative action of valproate is associated with aberrant expression and nuclear translocation of cyclin D3 during the C6 glioma G1 phase.

  Journal of neurochemistry 20021001

• PET study of the effects of valproate on dopamine D(2) receptors in neuroleptic- and mood-stabilizer-naive patients with nonpsychotic mania.

  The American journal of psychiatry 20021001

• Anticonvulsant actions of gap junctional blockers in an in vitro seizure model.

  Journal of neurophysiology 20021001

• A double-blind, randomized, placebo-controlled study of quetiapine as adjunctive treatment for adolescent mania.

  Journal of the American Academy of Child and Adolescent Psychiatry 20021001

• An open-label trial of divalproex in children and adolescents with bipolar disorder.

  Journal of the American Academy of Child and Adolescent Psychiatry 20021001

• Thrombocytopenia and megakaryocyte dysplasia: an adverse effect of valproic acid treatment.

  Journal of pediatric hematology/oncology 20021001

• Increase in postprandial serum insulin levels in epileptic patients with valproic acid therapy.

  Metabolism: clinical and experimental 20021001

• The Wnt signaling pathway in bipolar disorder.

  The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20021001

• Non convulsive status epilepticus after replacement of valproate with lamotrigine.

  Journal of neurology 20021001

• Valproic acid increases biliary copper excretion in the rat.

  Epilepsy research 20021001

• [A study of some indirect biochemical markers in the evaluation of enzymatic induction caused by antiepileptic drugs].

  Revista de neurologia 20021001

• Chronic treatment with both lithium and sodium valproate may normalize phosphoinositol cycle activity in bipolar patients.

  Human psychopharmacology 20021001

• Lamotrigine use in geriatric patients with bipolar depression.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20021001

• Recent developments in treatment of status epilepticus: a review.

  Epileptic disorders : international epilepsy journal with videotape 20021001

• Valproic acid is a structural analog of GABA that enters various metabolic pathways and has many clinical effects.

  The Journal of emergency medicine 20021001

• Renal injury from valproic acid: case report and literature review.

  Pediatric neurology 20021001

• Lithium and valproic acid: parallels and contrasts in diverse signaling contexts.

  Pharmacology & therapeutics 20021001

• Changes in body weight and body mass index among psychiatric patients receiving lithium, valproate, or topiramate: an open-label, nonrandomized chart review.

  Clinical therapeutics 20021001

• A pilot study of loading versus titration of valproate in the treatment of acute mania.

  Bipolar disorders 20021001

• Landau-Kleffner syndrome beginning with stuttering: case report.

  Journal of child neurology 20021001

• Does long-term use of valproate cause weight gain in prepubertal epileptic children?

  The International journal of neuroscience 20021001

• Statistical issues in the assessment of the evidence for an interaction between factors in epilepsy trials.

  Statistics in medicine 20020930

• Studies on functional sites of organic cation/carnitine transporter OCTN2 (SLC22A5) using a Ser467Cys mutant protein.

  The Journal of pharmacology and experimental therapeutics 20020901

• Mild generalized epilepsy and developmental disorder associated with large inv dup(15).

  Epilepsia 20020901

• Valproate-induced encephalopathy: assessment with MR imaging and 1H MR spectroscopy.

  Epilepsia 20020901

• Anti-tumor mechanisms of valproate: a novel role for an old drug.

  Medicinal research reviews 20020901

• Evaluation of highly bound drugs: interspecies, intersubject, and related comparisons.

  Journal of clinical pharmacology 20020901

• Treatment of bipolar disorder in older adults.

  International journal of geriatric psychiatry 20020901

• Induction of fetal hemoglobin synthesis by valproate: modulation of MAP kinase pathways.

  American journal of hematology 20020901

• Nuchal edema as the first sign of fetal valproate syndrome.

  Prenatal diagnosis 20020901

• Design of controlled release system with multi-layers of powder.

  Chemical & pharmaceutical bulletin 20020901

• Charcoal enhancement of treatment for tricyclic-induced mania.

  Pharmacopsychiatry 20020901

• Low glial numbers in the amygdala in major depressive disorder.

  Biological psychiatry 20020901

• Combination of carbamazepine and valproate in different dose proportions in maximal electroshock seizure model in mice.

  Epilepsy research 20020901

• [Landau-Kleffner and autistic regression: the importance of differential diagnosis].

  Arquivos de neuro-psiquiatria 20020901

• Sibutramine-induced mania episode in a bipolar patient.

  The international journal of neuropsychopharmacology 20020901

• Valproate and neuroprotection.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20020901

• Near reflex accommodation spasm: unusual presentation of generalized photosensitive epilepsy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20020901

• [Stiff-person syndrome].

  Nihon rinsho. Japanese journal of clinical medicine 20020901

• Differential gene expression in rats following subacute exposure to the anticonvulsant sodium valproate.

  Toxicology and applied pharmacology 20020901

• Sodium valproate prophylaxis in childhood migraine.

  Headache 20020901

• Serum lipids, vitamin B12 and folic acid levels in children receiving long-term valproate therapy.

  Acta neurologica Belgica 20020901

• Valproate embryopathy in three sets of siblings: further proof of hereditary susceptibility.

  Neurology 20020827

• New trial should clarify lithium use in bipolar disorder.

  BMJ (Clinical research ed.) 20020824

• Medical genetics: 1. Clinical teratology in the age of genomics.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020806

• Interaction of the neurosteroid alphaxalone with conventional antiepileptic drugs in different types of experimental seizures.

  European journal of pharmacology 20020802

• Valproate acidifies hippocampal CA3-neurons--a novel mode of action.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020801

• The use of divalproex in alcohol relapse prevention: a pilot study.

  Drug and alcohol dependence 20020801

• Pharmacokinetic and pharmacodynamic effects of clonazepam in children with epilepsy treated with valproate: a preliminary study.

  Therapeutic drug monitoring 20020801

• Valproate-associated dysmyelopoiesis in elderly patients.

  American journal of clinical pathology 20020801

• Early onset and rapidly progressive subacute sclerosing panencephalitis after congenital measles infection.

  European journal of pediatrics 20020801

• Valproate and valproate-analogues: potent tools to fight against cancer.

  Current medicinal chemistry 20020801

• Levetiracetam in autistic children: an open-label study.

  Journal of developmental and behavioral pediatrics : JDBP 20020801

• The effect on vision of associated treatments in patients taking vigabatrin: carbamazepine versus valproate.

  Epilepsia 20020801

• Divalproex extended-release versus the original divalproex tablet: results of a randomized, crossover study of well-controlled epileptic patients with primary generalized seizures.

  Epilepsy research 20020801

• Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.

  Epilepsy research 20020801

• [Reflex epilepsy from hot water: a new case and review of the literature].

  Revista de neurologia 20020801

• Pro- and anticoagulatory factors under sodium valproate-therapy in children.

  Neuropediatrics 20020801

• Effect of seizures and antiepileptic drugs on prolactin secretions.

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20020801

• The current state of treatment of status epilepticus.

  Current neurology and neuroscience reports 20020701

• Concordance as well as discordance for congenital malformations in valproate-exposed half-siblings with parental consanguinity may indicate a specific gene-teratogen interaction.

  Clinical dysmorphology 20020701

• Fulminant progression of hyperammonaemic encephalopathy after treatment with valproate in a patient with ureterosigmoidostomy.

  Journal of neurology, neurosurgery, and psychiatry 20020701

• Do lithium and anticonvulsants target the brain arachidonic acid cascade in bipolar disorder?

  Archives of general psychiatry 20020701

• Combination of a mood stabilizer with risperidone or haloperidol for treatment of acute mania: a double-blind, placebo-controlled comparison of efficacy and safety.

  The American journal of psychiatry 20020701

• Deepening coma in an epileptic patient: the missing link to the urea cycle. Hyperammonaemic metabolic encephalopathy.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020701

• Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer.

  American journal of clinical pathology 20020701

• Polycystic ovaries, obesity and insulin resistance in women with epilepsy. A comparative study of carbamazepine and valproic acid in 105 women.

  Journal of neurology 20020701

• Lithium and valproate treatment of pathological gambling: a randomized single-blind study.

  The Journal of clinical psychiatry 20020701

• Abnormal alterations in the metabolic patterns of patients on valproate therapy.

  The Journal of pharmacy and pharmacology 20020701

• Fatal pancreatitis associated with valproic acid: review of the literature.

  Medicine 20020701

• Combined clozapine and valproic acid treatment-induced agranulocytosis.

  European psychiatry : the journal of the Association of European Psychiatrists 20020701

• World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of bipolar disorders. Part I: Treatment of bipolar depression.

  The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20020701

• A randomized trial of divalproex sodium extended-release tablets in migraine prophylaxis.

  Neurology 20020611

• A crossover, add-on trial of talampanel in patients with refractory partial seizures.

  Neurology 20020611

• [Television, children and epilepsy].

  Nederlands tijdschrift voor geneeskunde 20020608

• Neurogenic differentiation of murine and human adipose-derived stromal cells.

  Biochemical and biophysical research communications 20020607

• DNA hypomethylating agents 5-aza-2'-deoxycytidine and valproate increase neuronal 5-lipoxygenase mRNA.

  European journal of pharmacology 20020607

• [Status epilepticus and its treatment].

  Orvosi hetilap 20020602

• Bone mineral status in ambulatory pediatric patients on long-term anti-epileptic drug therapy.

  Pediatrics international : official journal of the Japan Pediatric Society 20020601

• Remission of West syndrome associated with valproate hepatotoxicity.

  Brain & development 20020601

• Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.

  Therapeutic drug monitoring 20020601

• Evaluation of fluorescence polarization assays for measuring valproic acid, phenytoin, carbamazepine and phenobarbital in serum.

  Therapeutic drug monitoring 20020601

• Delayed valproic acid toxicity: a retrospective case series.

  Annals of emergency medicine 20020601

• Olanzapine versus divalproex in the treatment of acute mania.

  The American journal of psychiatry 20020601

• Quetiapine for olanzapine-induced galactorrhea.

  The American journal of psychiatry 20020601

• Valproic acid and risperidone.

  Journal of the American Academy of Child and Adolescent Psychiatry 20020601

• Management of rheumatic chorea: an observational study.

  Arquivos de neuro-psiquiatria 20020601

• Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons.

  Molecular and cellular neurosciences 20020601

• Sodium valproate in the treatment of aggressive behavior in patients with dementia--a randomized placebo controlled clinical trial.

  International journal of geriatric psychiatry 20020601

• Comparison of the efficacy of carbamazepine, haloperidol and valproic acid in the treatment of children with Sydenham's chorea: clinical follow-up of 18 patients.

  Arquivos de neuro-psiquiatria 20020601

• [Is treatment with a daily dose of Depakine Crono safe?].

  Revista de neurologia 20020601

• DP-VPA D-Pharm.

  Current opinion in investigational drugs (London, England : 2000) 20020601

• Intravenous valproate sodium in the treatment of daily headache.

  Headache 20020601

• Different dependence of lithium and valproate on PI3K/PKB pathway.

  Bipolar disorders 20020601

• Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage.

  Bipolar disorders 20020601

• Extinction of operant behavior as the test for cognitive disorders induced with kainic acid.

  Bulletin of experimental biology and medicine 20020601

• A common mechanism of action for three mood-stabilizing drugs.

  Nature 20020516

• Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice.

  European journal of pharmacology 20020510

• Valproic acid induces apoptosis in human leukemia cells by stimulating both caspase-dependent and -independent apoptotic signaling pathways.

  Leukemia research 20020501

• Ophthalmic findings in fetal anticonvulsant syndrome(s).

  Ophthalmology 20020501

• PET study of [(18)F]6-fluoro-L-dopa uptake in neuroleptic- and mood-stabilizer-naive first-episode nonpsychotic mania: effects of treatment with divalproex sodium.

  The American journal of psychiatry 20020501

• Protein binding of valproic acid in Japanese pediatric and adult patients with epilepsy.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20020501

• Concentration-dependent disposition of glucuronide metabolite of valproate.

  The Journal of pharmacy and pharmacology 20020501

• Protocols for identifying drug-nutrient interactions in patients: the role of the dietitian.

  Journal of the American Dietetic Association 20020501

• Nonadherence with mood stabilizers: prevalence and predictors.

  The Journal of clinical psychiatry 20020501

• A retrospective comparison of weight, lipid, and glucose changes between risperidone- and olanzapine-treated inpatients: metabolic outcomes after 1 year.

  The Journal of clinical psychiatry 20020501

• Divalproex sodium treatment of women with borderline personality disorder and bipolar II disorder: a double-blind placebo-controlled pilot study.

  The Journal of clinical psychiatry 20020501

• Do structural properties explain the anticonvulsant activity of valproate metabolites? A QSAR analysis.

  Epilepsia 20020501

• Carbamazepine versus valproate monotherapy for epilepsy: a meta-analysis.

  Epilepsia 20020501

• Serum insulin and leptin levels in valproate-associated obesity.

  Epilepsia 20020501

• Extracorporeal removal of toxic valproic acid levels in children.

  Pediatric nephrology (Berlin, Germany) 20020501

• Valproic acid therapy inducing absence status evolving into generalized seizures.

  Pediatric neurology 20020501

• Visual functions in epilepsy patients on valproate monotherapy.

  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20020501

• Hereditary haemochromatosis in two cousins with cluster headache.

  Cephalalgia : an international journal of headache 20020501

• Synaptic, intracellular, and neuroprotective mechanisms of anticonvulsants: are they relevant for the treatment and course of bipolar disorders?

  Journal of affective disorders 20020501

• Restless legs syndrome probably induced by risperidone treatment.

  Pharmacopsychiatry 20020501

• Valproate encephalopathy and hyperammonaemia.

  Postgraduate medical journal 20020501

• Lithium in bipolar mood disorder.

  BMJ (Clinical research ed.) 20020427

• A role for protein kinase C and its substrates in the action of valproic acid in the brain: implications for neural plasticity.

  Brain research 20020426

• Hyperperfusion with vasogenic leakage by fMRI in migraine with prolonged aura.

  Neurology 20020423

• Differential effects of histone deacetylase inhibitors on interleukin-18 gene expression in myeloid cells.

  Biochemical and biophysical research communications 20020412

• Pattern of response to divalproex, lithium, or placebo in four naturalistic subtypes of mania.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020401

• Influence on ictal seizure semiology of rapid withdrawal of carbamazepine and valproate in monotherapy.

  Epilepsia 20020401

• Topiramate enhances the risk of valproate-associated side effects in three children.

  Epilepsia 20020401

• Molsidomine enhances the protective activity of valproate against pentylenetetrazole-induced seizures in mice.

  Journal of neural transmission (Vienna, Austria : 1996) 20020401

• Low dose sodium valproate in the treatment of juvenile myoclonic epilepsy.

  Journal of neurology 20020401

• Pancreatitis complicating treatment with intravenous valproic acid.

  Journal of neurology 20020401

• Cerebellar ataxia with intravenous valproate and haloperidol.

  The Australian and New Zealand journal of psychiatry 20020401

• [Visual field defect in a patient given sodium valporate then carbamazepine: possible effect of aminotransferase inhibition].

  Revue neurologique 20020401

• Problems recruiting cancer patients to a comparative clinical trial of drug treatments for neuropathic pain in palliative care.

  Journal of pain and symptom management 20020401

• Menstrual abnormalities and polycystic ovary syndrome in women taking valproate for bipolar mood disorder.

  The Journal of clinical psychiatry 20020401

• Extended-release divalproex sodium improves the quality of life of adolescent migraineurs.

  Headache 20020401

• [Mitochondrial diseases due to drug toxicity].

  Nihon rinsho. Japanese journal of clinical medicine 20020401

• [Secondary carnitine deficiency].

  Nihon rinsho. Japanese journal of clinical medicine 20020401

• Phenobarbital-induced atypical absence seizure in benign childhood epilepsy with centrotemporal spikes.

  Seizure 20020401

• Reversible valproate-induced choreiform movements.

  Seizure 20020401

• A negative trial of sodium valproate in cluster headache: methodological issues.

  Cephalalgia : an international journal of headache 20020401

• Regulation of ER stress proteins by valproate: therapeutic implications.

  Bipolar disorders 20020401

• Insulin resistance in epileptic girls who gain weight after therapy with valproic acid.

  Journal of child neurology 20020401

• Epilepsy and pregnancy.

  Seizure 20020401

• Complete beta-oxidation of valproate: cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolase.

  The Biochemical journal 20020315

• Psychopathology, GABA, and the Rubinstein-Taybi syndrome: a review and case study.

  American journal of medical genetics 20020308

• Stress invalidates reported effects of sodium valproate on brain CRF systems.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020301

• In vivo evidence for brain-to-blood efflux transport of valproic acid across the blood-brain barrier.

  Microvascular research 20020301

• Sydenham's chorea: clinical findings and comparison of the efficacies of sodium valproate and carbamazepine regimens.

  Brain & development 20020301

• The effects of antiepileptic drugs on spatial learning and hippocampal protein kinase C gamma in immature rats.

  Brain & development 20020301

• Tubulo-interstitial nephritis caused by sodium valproate.

  Brain & development 20020301

• [Study of nine severely disabled children with hypouricemia].

  No to hattatsu = Brain and development 20020301

• Myoclonic status epilepticus: video presentation.

  Movement disorders : official journal of the Movement Disorder Society 20020301

• Unmasking of absence seizures by carbamazepine.

  Clinical pediatrics 20020301

• Coma probably induced by lorazepam-valproate interaction.

  Seizure 20020301

• Comparison of the bioavailability of unequal doses of divalproex sodium extended-release formulation relative to the delayed-release formulation in healthy volunteers.

  Epilepsy research 20020301

• Preliminary evaluation of oral anticonvulsant treatment in the quinpirole model of bipolar disorder.

  Journal of neural transmission (Vienna, Austria : 1996) 20020301

• Preliminary observations on valproate and cystic ovaries: letter to editor.

  Neurology India 20020301

• Effect of Withania somnifera glycowithanolides on a rat model of tardive dyskinesia.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020301

• Valproate-associated stomatitis.

  Journal of child neurology 20020301

• Altered pharmacokinetics and metabolism of valproate after replacement of conventional valproate with the slow-release formulation in epileptic patients.

  Pharmacology & toxicology 20020301

• Use of an immobilised human serum albumin HPLC column as a probe of drug-protein interactions: the reversible binding of valproate.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020225

• Carbapenem antibiotics inhibit valproic acid transport in Caco-2 cell monolayers.

  International journal of pharmaceutics 20020221

• [Hyperammonaemic coma after valproate therapy as adult onset of ornithine transcarbamylase deficiency].

  Medicina clinica 20020216

• Effect of L-carnitine treatment for valproate-induced hepatotoxicity.

  Neurology 20020212

• Valproate therapy for chronic, combat-induced posttraumatic stress disorder.

  Journal of clinical psychopharmacology 20020201

• New antiepileptic drugs currently in clinical trials: is there a strategy in their development?

  Therapeutic drug monitoring 20020201

• Severe acute valproic acid intoxication successfully treated with hemodiafiltration without hemoperfusion.

  Annals of emergency medicine 20020201

• Tricarboxylic acid cycle of glia in the in vivo human brain.

  NMR in biomedicine 20020201

• Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: involvement of NMDA receptor inhibition possibly by decreasing NR2B tyrosine phosphorylation.

  Journal of neurochemistry 20020201

• [Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)].

  Schmerz (Berlin, Germany) 20020201

• Divalproex sodium in the treatment of migraine and cluster headaches.

  The Journal of the American Osteopathic Association 20020201

• Smoldering myeloma associated with zonisamide treatment.

  Internal medicine (Tokyo, Japan) 20020201

• Intravenous valproate treatment: some observations.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20020201

• Stabilization of mood from below versus above baseline in bipolar disorder: a new nomenclature.

  The Journal of clinical psychiatry 20020201

• Proton gradient-dependent transport of valproic acid in human placental brush-border membrane vesicles.

  Pharmaceutical research 20020201

• Serum and CSF glutamine levels in valproate-related hyperammonemic encephalopathy.

  Epilepsia 20020201

• Chronic tension-type headache: advice for the viselike-headache patient.

  Cleveland Clinic journal of medicine 20020201

• Bipolar disorder.

  Lancet (London, England) 20020119

• Induction of differentiation and suppression of malignant phenotype of human neuroblastoma BE(2)-C cells by valproic acid: enhancement by combination with interferon-alpha.

  International journal of oncology 20020101

• Pharmacologic treatment of hospitalized patients with schizoaffective disorder.

  Psychiatric services (Washington, D.C.) 20020101

• Efficacy of olanzapine in combination with valproate or lithium in the treatment of mania in patients partially nonresponsive to valproate or lithium monotherapy.

  Archives of general psychiatry 20020101

• Re: Sodium valproate in cancer-related neuropathic pain.

  Journal of pain and symptom management 20020101

• Visual cortex excitability in migraine before and after valproate prophylaxis: a pilot study using TMS.

  European journal of neurology 20020101

• Molecular basis of environmentally induced birth defects.

  Annual review of pharmacology and toxicology 20020101

• Isolation and structure determination of obyanamide, a novel cytotoxic cyclic depsipeptide from the marine cyanobacterium Lyngbya confervoides.

  Journal of natural products 20020101

• Use of naloxone in valproic acid overdose: case report and review.

  The Journal of emergency medicine 20020101

• Propranolol and metoprolol enhance the anticonvulsant action of valproate and diazepam against maximal electroshock.

  Pharmacology, biochemistry, and behavior 20020101

• Typical and atypical rolandic epilepsy in childhood: a follow-up study.

  Pediatric neurology 20020101

• Serum copper, zinc, selenium, glutathione peroxidase and superoxide dismutase levels in epileptic children before and after 1 year of sodium valproate and carbamazepine therapy.

  Epilepsy research 20020101

• Hyperandrogenism, postprandial hyperinsulinism and the risk of PCOS in a cross sectional study of women with epilepsy treated with valproate.

  Epilepsy research 20020101

• Divalproex as a calmative adjunct for aggressive schizophrenic patients.

  The Journal of the Kentucky Medical Association 20020101

• Valproate-induced parkinsonism in a demented elderly patient.

  The Journal of clinical psychiatry 20020101

• Hemodialysis in the treatment of valproic acid overdose.

  The Journal of clinical psychiatry 20020101

• Epi-inositol regulates expression of the yeast INO1 gene encoding inositol-1-P synthase.

  Molecular psychiatry 20020101

• [Pharmacokinetic aspects of carbamazepine and valproic acid using in reproductive-age women with epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

• [Migraine: a disease, not a symptom].

  La Revue du praticien 20020101

• [Treatment of febrile convulsions].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20020101

• Randomized double-blind parallel-group study comparing cognitive effects of a low-dose lamotrigine with valproate and placebo in healthy volunteers.

  Epilepsia 20020101

• Valproate for catatonia: need for caution in patients on SSRIs and antipsychotics.

  The Journal of neuropsychiatry and clinical neurosciences 20020101

• Changes in brain complexity during valproate treatment in patients with partial epilepsy.

  Neuropsychobiology 20020101

• Predictors of treatment response in bipolar disorders: evidence from clinical and brain imaging studies.

  The Journal of clinical psychiatry 20020101

• Coagulation abnormalities and acquired von Willebrand's disease type 1 in children receiving valproic acid.

  Journal of child neurology 20020101

• Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention.

  Journal of addictive diseases 20020101

• [Treatment of epileptic seizures resistant to phenobarbital in children during the first year of life].

  Likars'ka sprava 20020101

• [Clinical importance of EEG changes during the treatment of epilepsy with valproate (depakene chrono)].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

• Divalproex in the management of neuropsychiatric complications of remote acquired brain injury.

  The Journal of neuropsychiatry and clinical neurosciences 20020101

• [Evaluation of antiepileptic therapy during pregnancy].

  Ginekologia polska 20020101

• [Valproate in the treatment of bipolar disorder].

  Psychiatria polska 20020101

• Children versus adults: pharmacokinetic and adverse-effect differences.

  Epilepsia 20020101

• Valproate-induced hyperammonemia as a cause of altered mental status.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20020101

• Valproate irreversibly alters steroid secretion patterns from porcine follicular cells in vitro.

  Reproductive toxicology (Elmsford, N.Y.) 20020101

• Synergistic effect of valproate coadministration and hypoalbuminemia on the serum-free phenytoin concentration in patients with severe motor and intellectual disabilities.

  Clinical neuropharmacology 20020101

• In vitro removal of therapeutic drugs with a novel adsorbent system.

  Blood purification 20020101

• [Severe oedema after valproate and valpromide].

  Therapie 20020101

• Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.

  Molecular psychiatry 20020101

• [Post-radiotherapy eruption in a patient treated with valproic acid. Rowell's syndrome?].

  Annales de dermatologie et de venereologie 20020101

• Ultrastructure of synaptic junctions in the cerebellar cortex in experimental valproate encephalopathy and after terminating chronic application of the antiepileptic.

  Folia neuropathologica 20020101

• Studies on the pharmacokinetics of total and free valproate in mono- and bitherapy with carbamazepine in epileptic children and adolescents.

  Folia neuropathologica 20020101

• [A case of familial paroxysmal kinesic choreoathetosis].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

• Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy.

  CNS drugs 20020101

• Pharmacological and therapeutic properties of valproate: a summary after 35 years of clinical experience.

  CNS drugs 20020101

• Fanconi syndrome caused by sodium valproate: report of three severely disabled children.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20020101

• Therapy of Sneddon syndrome.

  European neurology 20020101

• [Convulex and its place in epilepsy treatment with original valproates].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

• [Use of convulex in patients with epilepsy with and without affective disorders].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20020101

• Carbamazepine and valproate in the maintenance treatment of bipolar disorder.

  The Journal of clinical psychiatry 20020101

• Pathological case of the month: sudden death in a child as a result of pancreatitis during valproic acid therapy.

  Pediatric pathology & molecular medicine 20020101

• Effects of chronic valproate treatment on reproductive endocrine hormones in female and male Wistar rats.

  Reproductive toxicology (Elmsford, N.Y.) 20020101

• Comparative study of sodium valproate-induced skeletal malformations using single or double staining methods.

  Reproductive toxicology (Elmsford, N.Y.) 20020101

• Neural crest cell motility in valproic acid.

  Reproductive toxicology (Elmsford, N.Y.) 20020101

• Therapeutic drug monitoring of lamotrigine in patients suffering from resistant partial seizures.

  European neurology 20020101

• [Reversible parkinsonism induced by prolonged treatment with valproate].

  Therapie 20020101

• Can diabetes mellitus be induced by medication?

  Journal of child and adolescent psychopharmacology 20020101

• Cost-effectiveness of antiepileptic drugs in migraine prophylaxis.

  Headache 20020101

• [Drug-induced acute pancreatitis: a personal contribution].

  Chirurgia italiana 20020101

• Valproic acid toxicity: overview and management.

  Journal of toxicology. Clinical toxicology 20020101

• Myo-inositol-1-phosphate (MIP) synthase: a possible new target for antibipolar drugs.

  Bipolar disorders 20020101

• Can we conduct some large simple trials in bipolar disorder?

  Bipolar disorders 20020101

• Expression of G-proteins and regulators of G-protein signalling in neutrophils of patients with bipolar disorder: effects of mood stabilizers.

  Bipolar disorders 20020101

• [Bening epilepsy of childhood with centrotemporal spikes].

  Ryoikibetsu shokogun shirizu 20020101

• [Benign myoclonic epilepsy in infancy].

  Ryoikibetsu shokogun shirizu 20020101

• [Childhood absence epilepsy(pyknolepsy)].

  Ryoikibetsu shokogun shirizu 20020101

• [Juvenile absence epilepsy(JAE)].

  Ryoikibetsu shokogun shirizu 20020101

• [Juvenile myoclonic epilepsy].

  Ryoikibetsu shokogun shirizu 20020101

• [Epilepsy with GTCs on awakening].

  Ryoikibetsu shokogun shirizu 20020101

• [Other generalized epilepsies not defined above].

  Ryoikibetsu shokogun shirizu 20020101

• [West syndrome(infantile spasms)].

  Ryoikibetsu shokogun shirizu 20020101

• [Epilepsy with myoclonic absences].

  Ryoikibetsu shokogun shirizu 20020101

• [Unverricht-Lundborg disease].

  Ryoikibetsu shokogun shirizu 20020101

• [Epilepsy with continuous spikes and waves during slow sleep].

  Ryoikibetsu shokogun shirizu 20020101

• [Photosensitivity syndrome].

  Ryoikibetsu shokogun shirizu 20020101

• [Benign adult familial myoclonic epilepsy(BAFME)].

  Ryoikibetsu shokogun shirizu 20020101

• [Eyelid myoclonia with absences (EMA)].

  Ryoikibetsu shokogun shirizu 20020101

• [Neutropenia in a patient treated with clozapine in combination with other psychotropic drugs].

  L'Encephale 20020101

• Initial lithium and valproate combination therapy in acute mania.

  Neuropsychobiology 20020101

• Valproic acid in migraine prophylaxis of young patients. Three new reports.

  Acta bio-medica : Atenei Parmensis 20020101

• [Anticonvulsants (carbamazepine, valproate, lamotrigine) in bipolar affective disorder].

  Psychiatria polska 20020101

• Sodium valproate facilitates the propagation of granulocytic ehrlichiae (Anaplasma phagocytophilum) in HL-60 cells.

  Experimental & applied acarology 20020101

• Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells.

  The EMBO journal 20011217

• Analysis of the musculoskeletal system in children and adolescents receiving anticonvulsant monotherapy with valproic acid or carbamazepine.

  Pediatrics 20011201

• The acute effect of valproate on cerebral energy metabolism in mice.

  Epilepsy research 20011201

• Pancreatitis associated with valproic acid: a review of the literature.

  Pharmacotherapy 20011201

• Acute valproate-associated microvesicular steatosis: could the [13C]methionine breath test be useful to assess liver mitochondrial function?

  Digestive diseases and sciences 20011201

• 'Foetal valproate syndrome and autism: additional evidence of an association'.

  Developmental medicine and child neurology 20011201

• [Remission of epilepsy after onset of antiepileptic treatment: a prospective study in childhood].

  Revista de neurologia 20011201

• Morphological changes in the testis after long-term valproate treatment in male Wistar rats.

  Seizure 20011201

• Video game epilepsy.

  Neurology India 20011201

• Population pharmacokinetics of lamotrigine.

  Therapeutic drug monitoring 20011201

• Methsuximide reduces valproic acid serum levels.

  Therapeutic drug monitoring 20011201

• [Metopic craniosynostosis, probable effect of intrauterine exposure to maternal valproate treatment].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20011201

• Reversible aphasic disorder induced by lamotrigine in atypical benign childhood epilepsy.

  Epileptic disorders : international epilepsy journal with videotape 20011201

• Ultrastructure of Purkinje cell perikarya and their dendritic processes in the rat cerebellar cortex in experimental encephalopathy induced by chronic application of valproate.

  International journal of experimental pathology 20011201

• Serum lipid changes during anticonvulsive treatment serum lipids in epileptic children.

  Acta neurologica Belgica 20011201

• Valproate in very young children: an open case series with a brief follow-up.

  Journal of affective disorders 20011201

• Divalproex therapy in medication-naive and mood-stabilizer-naive bipolar II depression.

  Journal of affective disorders 20011201

• Current research on rapid cycling bipolar disorder and its treatment.

  Journal of affective disorders 20011201

• Clinical correlates of therapeutic response in bipolar disorder.

  Journal of affective disorders 20011201

• [Teratogenic action of antiepileptic drug: 2-propylpentanoic acid-effects on rat and hamster embryos cultured in vitro].

  Ginekologia polska 20011201

• [Monitoring of renal function in epileptic children and teenagers treated with valproic acid or carbamazepine in concomitant therapy with tiagabine].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20011201

• [Treatment of newly diagnosed epileptic crises. A French experience].

  Revue neurologique 20011201

• [Clinical features and treatment of refractory epilepsy in children].

  Rinsho shinkeigaku = Clinical neurology 20011201

• Neuropsychological assessment in children with absence epilepsy.

  Neurology 20011127

• Inhibition of proliferation of HT-29 colon adenocarcinoma cells by carboxylate NSAIDs and their acyl glucuronides.

  Life sciences 20011121

• Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.

  Chemical communications (Cambridge, England) 20011121

• Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives.

  European journal of pharmacology 20011109

• Valproic acid triggers acute rhabdomyolysis in a patient with carnitine palmitoyltransferase type II deficiency.

  Neuromuscular disorders : NMD 20011101

• Treatment of febrile seizures: the influence of treatment efficacy and side-effect profile on value to parents.

  Pediatrics 20011101

• National survey on West syndrome in Korea.

  Brain & development 20011101

• Craniosynostosis and fetal exposure to sodium valproate.

  Journal of neurosurgery 20011101

• Prevalence and risk of thrombocytopenia with valproic acid: experience at a psychiatric teaching hospital.

  Pharmacotherapy 20011101

• Retrospective evaluation of the effect of valproate therapy on transaminase elevations in patients with hepatitis C.

  Pharmacotherapy 20011101

• Intravenous valproate in status epilepticus.

  The Annals of pharmacotherapy 20011101

• [Seizure and developmental prognosis of West syndrome--combination therapy with high-dose vitamin B6, valproate and low-dose ACTH].

  No to hattatsu = Brain and development 20011101

• In vitro evaluation of valproic acid as an inhibitor of human cytochrome P450 isoforms: preferential inhibition of cytochrome P450 2C9 (CYP2C9).

  British journal of clinical pharmacology 20011101

• Characterization of plasma acylcarnitines in patients under valproate monotherapy using ESI-MS/MS.

  Clinical biochemistry 20011101

• Monotherapy versus polytherapy for epilepsy: a multicenter double-blind randomized study.

  Epilepsia 20011101

• [Agranulocytosis and simultaneous cholestatic jaundice induced by sodium valproate in an elderly woman].

  Presse medicale (Paris, France : 1983) 20011006

• Cerebral vein thrombosis and prothrombin gene (G20210A) mutation.

  Clinical neurology and neurosurgery 20011001

• Hyperammonemia and coma without hepatic dysfunction induced by valproate therapy.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20011001

• [Lafora's disease: one of the causes for drug-resistant epilepsy in adolescence].

  Minerva pediatrica 20011001

• Pediatric migraine prophylaxis with divalproex.

  Journal of child neurology 20011001

• Uremic sera contain inhibitors that block digitoxin-valproic acid interaction.

  The American journal of the medical sciences 20011001

• Cervical flexion myelopathy after valproic acid overdose.

  Spine 20011001

• Synthesis of valproic acid amides of a melatonin derivative, a piracetam and amantadine for biological tests.

  Neurochemical research 20011001

• Reduced corneal sensation and severe dry eyes in a child with fetal valproate syndrome.

  Eye (London, England) 20011001

• Corticosteroid-induced acute mania during a cluster headache episode.

  Cephalalgia : an international journal of headache 20011001

• Effectiveness of first antiepileptic drug.

  Epilepsia 20011001

• Comparison of the anticonvulsant efficacies and neurotoxic effects of valproic acid, phenytoin, and the ketogenic diet.

  Epilepsia 20011001

• Low serum biotinidase activity in children with valproic acid monotherapy.

  Epilepsia 20011001

• Fatal cardiac malformation in fetal valproate syndrome.

  Indian journal of pediatrics 20011001

• Aspirin modulates the anticonvulsant effect of diazepam and sodium valproate in pentylenetetrazole and maximal electroshock induced seizures in mice.

  Indian journal of physiology and pharmacology 20011001

• Interaction of flunarizine with sodium valproate or ethosuximide in gamahydroxybutyrate induced absence seizures in rats.

  Indian journal of experimental biology 20011001

• The evolving role of topiramate among other mood stabilizers in the management of bipolar disorder.

  Bipolar disorders 20011001

• Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen.

  The Journal of biological chemistry 20010928

• Differential effect of valproate and its Delta2- and Delta4-unsaturated metabolites, on the beta-oxidation rate of long-chain and medium-chain fatty acids.

  Chemico-biological interactions 20010928

• Effect of alpha-fluorination of valproic acid on valproyl-S-acyl-CoA formation in vivo in rats.

  Drug metabolism and disposition: the biological fate of chemicals 20010901

• Effect of alkylpyrazine derivatives on the duration of pentobarbital-induced sleep, picrotoxicin-induced convulsion and gamma-aminobutyric acid (GABA) levels in the mouse brain.

  Biological & pharmaceutical bulletin 20010901

• Pharmacokinetics of valproic acid in patients with bipolar disorder.

  Journal of psychopharmacology (Oxford, England) 20010901

• Altered ovarian function and cardiovascular risk factors in valproate-treated women.

  The American journal of medicine 20010901

• Valproic acid is effective in migraine prophylaxis at low serum levels: a prospective open-label study.

  Headache 20010901

• Long-term valproate and lamotrigine treatment may be a marker for reduced growth and bone mass in children with epilepsy.

  Epilepsia 20010901

• Divalproex sodium in alcohol withdrawal: a randomized double-blind placebo-controlled clinical trial.

  Alcoholism, clinical and experimental research 20010901

• Utility of a new assay for carbohydrate-deficient transferrin (Biorad %CDT TIA) to monitor abstinence during a treatment outcome study.

  Alcoholism, clinical and experimental research 20010901

• [Fatal necro-hemorrhagic pancreatitis related to sodium valproate: case report].

  Arquivos de neuro-psiquiatria 20010901

• Quetiapine alone and added to a mood stabilizer for serious mood disorders.

  The Journal of clinical psychiatry 20010901

• Effect of meropenem on disposition kinetics of valproate and its metabolites in rabbits.

  Pharmaceutical research 20010901

• Evolution of juvenile myoclonic epilepsy treated from the outset with sodium valproate.

  Seizure 20010901

• Nonstationary disposition of valproic acid during prolonged intravenous infusion: contributions of unbound clearance and protein binding.

  Biopharmaceutics & drug disposition 20010901

• Effect of anticonvulsant drugs on interleukins-1, -2 and -6 and monocyte chemoattractant protein-1.

  Clinical and experimental medicine 20010901

• The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth.

  The Journal of biological chemistry 20010824

• [Cerebral vasculitis as the initial manifestation of systemic lupus erythematosus].

  Deutsche medizinische Wochenschrift (1946) 20010824

• Early hormonal changes during valproate or carbamazepine treatment: a 3-month study.

  Neurology 20010814

• Decreased bone mass and increased bone turnover with valproate therapy in adults with epilepsy.

  Neurology 20010814

• Weight change associated with valproate and lamotrigine monotherapy in patients with epilepsy.

  Neurology 20010814

• Epilepsy.

  The New England journal of medicine 20010809

• Severe, isolated thrombocytopenia under polytherapy with carbamazepine and valproate.

  Psychiatry and clinical neurosciences 20010801

• Selection bias in Teratology Information Service pregnancy outcome studies.

  Teratology 20010801

• Septo-optic dysplasia as a manifestation of valproic acid embryopathy.

  Teratology 20010801

• Stereoselective pharmacokinetic analysis and antiepileptic activity of N-2-hydroxypropyl valpromide, a central nervous system--active chiral valproylamide.

  Therapeutic drug monitoring 20010801

• Effect of divalproex-lamotrigine combination therapy in frontal lobe seizures.

  Archives of neurology 20010801

• Valproic acid and risperidone.

  Journal of the American Academy of Child and Adolescent Psychiatry 20010801

• Alternative medicine. Achieving balance between herbal remedies and medical therapy.

  Geriatrics 20010801

• Valproate induces in vitro accumulation of long-chain fatty acylcarnitines.

  Molecular genetics and metabolism 20010801

• Changes in the antioxidant system in epileptic children receiving antiepileptic drugs: two-year prospective studies.

  Journal of child neurology 20010801

• Long-term naturalistic treatment of depressive symptoms in bipolar illness with divalproex vs. lithium in the setting of minimal antidepressant use.

  Journal of affective disorders 20010801

• Pentyl-4-yn-valproic acid enhances both spatial and avoidance learning, and attenuates age-related NCAM-mediated neuroplastic decline within the rat medial temporal lobe.

  Journal of neurochemistry 20010801

• Effectiveness of haemofiltration in valproic acid intoxication.

  Acta paediatrica (Oslo, Norway : 1992) 20010801

• Increased risk of neutropaenia and agranulocytosis with sodium valproate used adjunctively with clozapine.

  The Australian and New Zealand journal of psychiatry 20010801

• Hormone profiles in young adults with epilepsy treated with sodium valproate or lamotrigine monotherapy.

  Epilepsia 20010801

• Stupor from lamotrigine toxicity.

  Epilepsia 20010801

• Are serum anticonvulsant levels in people with epilepsy appropriately monitored?

  Journal of evaluation in clinical practice 20010801

• [Rolandic discharges in childhood epilepsy: magnetoencephalographic diagnosis].

  Revista de neurologia 20010801

• Determination of valproic acid in serum by liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010801

• Disodium valproate: new preparation. An alternative for acute mania after lithium failure or intolerance.

  Prescrire international 20010801

• Valproate-induced encephalopathy.

  Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20010801

• Multiple mitochondrial DNA deletions and lactic acidosis in an HIV-infected patient under antiretroviral therapy.

  AIDS (London, England) 20010727

• Valproic acid toxicity mimicking multiple system atrophy.

  Neurology 20010710

• Valproic acid overdose and haemodialysis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010701

• Gender- or age-related binding characteristics of valproic acid to serum proteins in adult patients with epilepsy.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20010701

• Juvenile myoclonic epilepsy--an experience from north western India.

  Acta neurologica Scandinavica 20010701

• Polycystic ovarian syndrome--relationship to epilepsy and antiepileptic drug therapy.

  The Journal of clinical endocrinology and metabolism 20010701

• Characterization of reproductive endocrine disorders in women with epilepsy.

  The Journal of clinical endocrinology and metabolism 20010701

• Retrospective analysis of serum valproate levels and need for an antidepressant drug.

  Pharmacotherapy 20010701

• Microlissencephaly with cardiac, spinal and urogenital defects.

  Clinical dysmorphology 20010701

• Valproic acid, trichostatin and their combination with hemin preferentially enhance gamma-globin gene expression in human erythroid liquid cultures.

  Haematologica 20010701

• Treatment of epilepsy in 3 specialized populations.

  The American journal of managed care 20010701

• [Hypernatremia as a rare complication in change from lithium to valproate].

  Der Nervenarzt 20010701

• Thyroid hormones in epileptic children receiving carbamazepine and valproic acid.

  Pediatric neurology 20010701

• Olanzapine therapy in treatment-resistant psychotic mood disorders: a long-term follow-up study.

  The Journal of clinical psychiatry 20010701

• An open trial of divalproex sodium in autism spectrum disorders.

  The Journal of clinical psychiatry 20010701

• Thyroid function in men taking carbamazepine, oxcarbazepine, or valproate for epilepsy.

  Epilepsia 20010701

• Absence seizures aggravated by valproic acid.

  Epilepsia 20010701

• [Prophylactic long-term therapy of affective disorders with lithium, valproic acid and carbamazepine--effectiveness and cost-effectiveness].

  Psychiatrische Praxis 20010701

• [Piracetam in the treatment of a patient with idiopathic cortical myoclonus].

  Revista de neurologia 20010701

• Effects of sodium valproate on corticotropin-releasing factor systems in rat brain.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010601

• Molecular cloning of a novel isoform of diphosphoinositol polyphosphate phosphohydrolase: a potential target of lithium therapy.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010601

• Continuum solvent model studies of the interactions of an anticonvulsant drug with a lipid bilayer.

  Biophysical journal 20010601

• An unusual presentation of opioid-like syndrome in pediatric valproic acid poisoning.

  Veterinary and human toxicology 20010601

• Double-blind, placebo-controlled comparison of imipramine and paroxetine in the treatment of bipolar depression.

  The American journal of psychiatry 20010601

• Up-regulation of hippocampal glutamate transport during chronic treatment with sodium valproate.

  Journal of neurochemistry 20010601

• Status epilepticus.

  Pediatric clinics of North America 20010601

• Sodium valproate-induced cutaneous pseudolymphoma followed by recurrence with carbamazepine.

  The British journal of dermatology 20010601

• Repeated neural tube defects and valproate monotherapy suggest a pharmacogenetic abnormality.

  Epilepsia 20010601

• Prognostic significance of failure of the initial antiepileptic drug in children with absence epilepsy.

  Epilepsia 20010601

• Effect of lithium and sodium valproate ions on resting membrane potentials in neurons: an hypothesis.

  Journal of affective disorders 20010601

• Inhibition by carbapenem antibiotic imipenem of intestinal absorption of valproic acid in rats.

  The Journal of pharmacy and pharmacology 20010601

• Mood stabilizers in Asperger's syndrome.

  The Australian and New Zealand journal of psychiatry 20010601

• We need better preventative medications.

  Headache 20010601

• Landau Kleffner syndrome.

  Indian journal of pediatrics 20010601

• [Metopic suture craniosynostosis: sodium valproate teratogenic effect. Case report].

  Arquivos de neuro-psiquiatria 20010601

• Comparative effects of valproic acid sodium for Chiari-like malformation at 9 and 10 days of gestation in the rat.

  Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20010601

• Does EEG predict response to valproate versus lithium in patients with mania?

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20010601

• Methylphenidate sensitization is modulated by valproate.

  Life sciences 20010525

• Effect of L-carnitine treatment for valproate-induced hepatotoxicity.

  Neurology 20010522

• Hyperactivity and alopecia associated with ingestion of valproic acid in a cat.

  Journal of the American Veterinary Medical Association 20010515

• Lithium and valproate decrease inositol mass and increase expression of the yeast INO1 and INO2 genes for inositol biosynthesis.

  The Journal of biological chemistry 20010504

• Dose-dependent pharmacokinetics and metabolism of valproic acid in newborn lambs and adult sheep.

  Drug metabolism and disposition: the biological fate of chemicals 20010501

• Induction of differentiation in F9 cells and activation of peroxisome proliferator-activated receptor delta by valproic acid and its teratogenic derivatives.

  Molecular pharmacology 20010501

• Divalproex sodium in sex offenders with bipolar disorders and comorbid paraphilias: an open retrospective study.

  Journal of affective disorders 20010501

• Heparin-induced release of protein-bound solutes during hemodialysis is an in vitro artifact.

  Clinical chemistry 20010501

• Chronic valproate treatment decreases the in vivo turnover of arachidonic acid in brain phospholipids: a possible common effect of mood stabilizers.

  Journal of neurochemistry 20010501

• Probenecid-associated alterations in valproic acid pharmacokinetics in rats: can in vivo disposition of valproate glucuronide be predicted from in vitro formation data?

  Drug metabolism and disposition: the biological fate of chemicals 20010501

• Antiepileptic drug therapy and its management in sudden unexpected death in epilepsy: a case-control study.

  Epilepsia 20010501

• Dubious about Depakote.

  Headache 20010501

• The effect of divalproex sodium on viral load: a retrospective review of HIV-positive patients with manic syndromes.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20010501

• The use of intravenous valproate in psychiatry.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20010501

• Latent coeliac disease in a child with epilepsy, cerebral calcifications, drug-induced systemic lupus erythematosus and intestinal folic acid malabsorption associated with impairment of folic acid transport across the blood-brain barrier.

  European journal of pediatrics 20010501

• Effect of Antiepileptic drugs on plasma lipoprotein (a) and other lipid levels in childhood.

  Journal of child neurology 20010501

• CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity.

  Clinical biochemistry 20010501

• Simultaneous side effects of both clozapine and valproate.

  Intensive care medicine 20010501

• Overexpression of components of the Frizzled-Dishevelled cascade results in apoptotic cell death, mediated by beta-catenin.

  Experimental cell research 20010415

• Uptake mechanism of valproic acid in human placental choriocarcinoma cell line (BeWo).

  European journal of pharmacology 20010413

• The teratogenicity of anticonvulsant drugs.

  The New England journal of medicine 20010412

• Comparison the cognitive effect of anti-epileptic drugs in seizure-free children with epilepsy before and after drug withdrawal.

  Epilepsy research 20010401

• Probenecid-associated alterations in valproate glucuronide hepatobiliary disposition: mechanistic assessment using mathematical modeling.

  The Journal of pharmacology and experimental therapeutics 20010401

• Epilepsy therapy: issues for women and men.

  Current opinion in neurology 20010401

• Treatment of borderline personality disorder with mood instability with divalproex sodium: series of ten cases.

  Journal of clinical psychopharmacology 20010401

• New-onset absence status epilepsy presenting as altered mental status in a pediatric patient.

  Annals of emergency medicine 20010401

• Novel treatments for bipolar disorder.

  Expert opinion on investigational drugs 20010401

• Cluster headache: review of the literature.

  The British journal of oral & maxillofacial surgery 20010401

• Special issues in the treatment of paediatric bipolar disorder.

  Expert opinion on pharmacotherapy 20010401

• [Hyperammonia, hypoglycemia and thrombocytopenia in a newborn after materanl treatment with valproate].

  Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20010401

• Case reports.

  Seizure 20010401

• Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.

  Epilepsia 20010401

• Assessment of tear concentrations on therapeutic drug monitoring. II. Pharmacokinetic analysis of valproic acid in guinea pig serum, cerebrospinal fluid, and tears.

  Pharmaceutical research 20010401

• Synthesis and intramitochondrial levels of valproyl-coenzyme A metabolites.

  Analytical biochemistry 20010301

• A phase II study to establish the efficacy and toxicity of sodium valproate in patients with cancer-related neuropathic pain.

  Journal of pain and symptom management 20010301

• Mood-stabilisers reduce the risk of developing antidepressant-induced maniform states in acute treatment of bipolar I depressed patients.

  Journal of affective disorders 20010301

• Fetal valproate syndrome and autism: additional evidence of an association.

  Developmental medicine and child neurology 20010301

• Divalproex in the long-term treatment of chronic daily headache.

  Headache 20010301

• Effects of antimanic mood-stabilizing drugs on fetuses, neonates, and nursing infants.

  Southern medical journal 20010301

• A preliminary double-blind, placebo-controlled trial of divalproex sodium in borderline personality disorder.

  The Journal of clinical psychiatry 20010301

• Renal tubular dysfunction in epileptic children on valproic acid therapy.

  Pediatric nephrology (Berlin, Germany) 20010301

• Valproic acid sodium-induced spina bifida occulta in the rat.

  Neurosurgical review 20010301

• Mood stabilizers regulate cytoprotective and mRNA-binding proteins in the brain: long-term effects on cell survival and transcript stability.

  The international journal of neuropsychopharmacology 20010301

• Identification of mood stabilizer-regulated genes by differential-display PCR.

  The international journal of neuropsychopharmacology 20010301

• Nonconvulsive status epilepticus causing acute confusion.

  Age and ageing 20010301

• [Encephalopathy induced by ingestion of ammonium during valproate therapy].

  Gastroenterologie clinique et biologique 20010301

• Valproic acid and thrombocytopenia: cross-sectional study.

  Hong Kong medical journal = Xianggang yi xue za zhi 20010301

• On the association between valproate and polycystic ovary syndrome.

  Epilepsia 20010301

• On the association between valproate and polycystic ovary syndrome: a response and an alternative view.

  Epilepsia 20010301

• Valproate and the polycystic ovarian syndrome: final thoughts.

  Epilepsia 20010301

• Anticonvulsant activity of N-palmitoylethanolamide, a putative endocannabinoid, in mice.

  Epilepsia 20010301

• Enhanced anticonvulsant activity of neuroactive steroids in a rat model of catamenial epilepsy.

  Epilepsia 20010301

• Absence epilepsy with fast rhythmic discharges during sleep: an intermediary form of generalized epilepsy?

  Epilepsia 20010301

• [Febrile convulsions, Treatment and prognosis].

  Ugeskrift for laeger 20010219

• Independent short-term variability of spike-like (600 Hz) and postsynaptic (N20) cerebral SEP components.

  Neuroreport 20010212

• The impact of pharmacogenetics for migraine.

  European journal of pharmacology 20010209

• Different control of GH secretion by gamma-amino- and gamma-hydroxy-butyric acid in 4-year abstinent alcoholics.

  Drug and alcohol dependence 20010201

• Divalproex sodium augmentation of haloperidol in hospitalized patients with schizophrenia: clinical and economic implications.

  Journal of clinical psychopharmacology 20010201

• Melt pelletization of a hygroscopic drug in a high shear mixer. Part 3. Effects of binder variation.

  Chemical & pharmaceutical bulletin 20010201

• Treatment of impulsivity and aggression in a patient with vascular dementia.

  Geriatrics 20010201

• Glutamate receptor antagonists differentially affect the protective activity of conventional antiepileptics against amygdala-kindled seizures in rats.

  European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010201

• A case of chronic pancreatic insufficiency due to valproic acid in a child.

  Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20010201

• Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring.

  Epilepsia 20010201

• Distribution of valproate to subdural cerebrospinal fluid, subcutaneous extracellular fluid, and plasma in humans: a microdialysis study.

  Epilepsia 20010201

• Valproate and the risk of hyperandrogenism.

  Bipolar disorders 20010201

• Valproate, but not lamotrigine, induces ovarian morphological changes in Wistar rats.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20010201

• [Sodium valproate-induced kinky hair].

  Annales de dermatologie et de venereologie 20010201

• Nitroso-urea-cisplatin-based chemotherapy associated with valproate: increase of haematologic toxicity.

  Annals of oncology : official journal of the European Society for Medical Oncology 20010201

• [Use of lamotrigine in the treatment of absence epilepsy crises].

  Revista de neurologia 20010201

• [Antiepileptic drugs and neuropathic pain].

  Revista de neurologia 20010201

• Weight change associated with valproate and lamotrigine monotherapy in patients with epilepsy.

  Neurology 20010123

• [Febrile pleuropericarditis during valproic acid treatment].

  Presse medicale (Paris, France : 1983) 20010120

• Valproic acid embryopathy: report of two siblings with further expansion of the phenotypic abnormalities and a review of the literature.

  American journal of medical genetics 20010115

• Reproductive effects of valproate, carbamazepine, and oxcarbazepine in men with epilepsy.

  Neurology 20010109

• Hypothermia and thermoregulatory derangements induced by valproic acid.

  Neurology 20010109

• Occurrence of thrombocytopenia in psychiatric patients taking valproate.

  The American journal of psychiatry 20010101

• Does genomic imprinting contribute to valproic acid teratogenicity?

  Reproductive toxicology (Elmsford, N.Y.) 20010101

• Clozapine therapy for a patient with a history of Hodgkin's disease.

  Psychiatric services (Washington, D.C.) 20010101

• Placebo-controlled study of divalproex sodium for agitation in dementia.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20010101

• Mood stabilizers and ion regulation.

  Harvard review of psychiatry 20010101

• Contribution of sodium valproate to the syndrome of inappropriate secretion of antidiuretic hormone.

  International clinical psychopharmacology 20010101

• Benzodiazepines and anticonvulsants for social phobia (social anxiety disorder).

  The Journal of clinical psychiatry 20010101

• Evaluating the tolerability of the newer mood stabilizers.

  The Journal of nervous and mental disease 20010101

• Action of valproic acid on Xenopus laevis development: teratogenic effects on eyes.

  Teratogenesis, carcinogenesis, and mutagenesis 20010101

• Pharmacologic treatment of patients hospitalized with the diagnosis of schizoaffective disorder.

  The Journal of clinical psychiatry 20010101

• A 25-year-old woman with bipolar disorder.

  JAMA 20010101

• Valproic acid has temporal variability in urinary clearance of metabolites.

  Chronobiology international 20010101

• New developments in the pharmacotherapy of alcohol dependence.

  The American journal on addictions 20010101

• Anxiolytic effects of valproate and diazepam in mice are differentially sensitive to picrotoxin antagonism.

  Pharmacology, biochemistry, and behavior 20010101

• Carnitine protects mitochondria and removes toxic acyls from xenobiotics.

  Drugs under experimental and clinical research 20010101

• Different effects of valproic acid on proliferation and migration of malignant glioma cells in vitro.

  Anticancer research 20010101

• Valproate-related edema.

  Clinical neuropharmacology 20010101

• Epileptic nystagmus: electroclinical study of a case.

  Epileptic disorders : international epilepsy journal with videotape 20010101

• Tolerability of oral loading of divalproex sodium in child psychiatry inpatients.

  Journal of child and adolescent psychopharmacology 20010101

• The concentration of three anti-seizure medications in hair: the effects of hair color, controlling for dose and age.

  BMC clinical pharmacology 20010101

• [Studies of damaged processes in the nervous system and possibilities of neuroprotection].

  Przeglad lekarski 20010101

• Prediction of embryotoxic effects of valproic acid-derivatives with molecular in vitro methods.

  ALTEX 20010101

• [Effectiveness and safety of topiramate in treatment-resistant bipolar disorder].

  Actas espanolas de psiquiatria 20010101

• Intravenous valproic acid in the treatment of severe catatonia.

  The Journal of neuropsychiatry and clinical neurosciences 20010101

• [Fetal valproate syndrome].

  Ryoikibetsu shokogun shirizu 20010101

• Cognitive side effects of anticonvulsants.

  The Journal of clinical psychiatry 20010101

• Introduction: the role of anticonvulsants as mood stabilizers.

  The Journal of clinical psychiatry 20010101

• Bipolar rapid cycling: focus on depression as its hallmark.

  The Journal of clinical psychiatry 20010101

• Uses of intravenous valproate in geriatric psychiatry.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20010101

• [Partial benign crises in adolescence].

  Neurologia (Barcelona, Spain) 20010101

• [Prediction of treatment response in acute mania: controlled clinical trials with divalproex].

  L'Encephale 20010101

• [The influence of mood-normalizing agents on cognitive functions].

  Psychiatria polska 20010101

• Inhibition by anticonvulsants of prostate-specific antigen and interleukin-6 secretion by human prostate cancer cells.

  Anticancer research 20010101

• [Depakene (sodium valproate) in the treatment of epilepsy in children and adolescents: efficiency and safety].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20010101

• The management of refractory idiopathic epilepsies.

  Epilepsia 20010101

• Polycystic ovarian syndrome in women with epilepsy: a review.

  Epilepsia 20010101

• The effect of drugs and toxins on the process of apoptosis.

  Drug metabolism and drug interactions 20010101

• The effects of lithium, valproic acid, and carbamazepine during pregnancy and lactation.

  Journal of toxicology. Clinical toxicology 20010101

• A unique valproic acid ingestion.

  Journal of toxicology. Clinical toxicology 20010101

• Antiepileptic drugs for the acute and maintenance treatment of bipolar disorder.

  Harvard review of psychiatry 20010101

• Establishing individual metabolite patterns for patients on valproate therapy.

  European journal of drug metabolism and pharmacokinetics 20010101

• Prevention and management of febrile seizures.

  Paediatric drugs 20010101

• [Secondary carnitine deficiency].

  Ryoikibetsu shokogun shirizu 20010101

• [Brief history of the development of valproate in bipolar disorders].

  L'Encephale 20010101

• Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder.

  The Cochrane database of systematic reviews 20010101

• Phenytoin versus valproate monotherapy for partial onset seizures and generalized onset tonic-clonic seizures.

  The Cochrane database of systematic reviews 20010101

• [Analogs of generic preparations for the treatment of epilepsy: is their use safe?].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20010101

• Divalproex loading in the treatment of cocaine dependence.

  Journal of psychoactive drugs 20010101

• Developments in mood stabilisers.

  British medical bulletin 20010101

• Agitation as a paradoxical effect of divalproex sodium: a case report.

  The Journal of neuropsychiatry and clinical neurosciences 20010101

• [The pharmacological and hormonal effects of carbamazepine and valproic acid in the treatment of reproductive age women with epilepsy].

  Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20010101

• Pancreatitis induced by valproic acid: report of a case.

  Surgery today 20010101

• Evaluation of interaction between valproate and baclofen in the formalin test in mice.

  Polish journal of pharmacology 20010101

• Previous prolonged clonic seizures diminish antiepileptic activity of valproate against pentetrazol-evoked convulsions.

  Polish journal of pharmacology 20010101

• Comparison of intravenous valproate versus intramuscular dihydroergotamine and metoclopramide for acute treatment of migraine headache.

  Headache 20010101

• Antiepileptic drugs in migraine prevention.

  Headache 20010101

• [Update on the pharmacological treatment of bipolar disorder].

  Vertex (Buenos Aires, Argentina) 20010101

• Morphometric analysis of the cerebellar cortex capillaries in the course of experimental valproate encephalopathy and after chronic exposure to sodium valproate using transmission electron microscopy.

  Folia neuropathologica 20010101

• Nociceptive changes in rats after prenatal exposure to valproic acid.

  Polish journal of pharmacology 20010101

• Effect of sodium valproate on somatosensory evoked potentials in juvenile myoclonic epilepsy.

  Upsala journal of medical sciences 20010101

• Postimplantation whole embryo culture assay for hamsters: an alternative to rat and mouse.

  TheScientificWorldJournal 20010101

• Valproate and other anticonvulsants for psychiatric disorders.

  The Medical letter on drugs and therapeutics 20001211

• Nonspecific stimulation of the maternal immune system. I. Effects On teratogen-induced fetal malformations.

  Teratology 20001201

• [Lyell syndrome associated with lamotrigine].

  Revista de neurologia 20001201

• Renal tubular function in patients receiving anticonvulsant therapy: a long-term study.

  Epilepsia 20001101

• Valpromide increases amplitude of heart rate circadian rhythm in remitted bipolar and unipolar disorders. A placebo-controlled study.

  European psychiatry : the journal of the Association of European Psychiatrists 20001101

• A case of pharmacokinetic interference in comedication of clozapine and valproic acid.

  Pharmacopsychiatry 20001101

• In vivo study of the effect of valpromide and valnoctamide in the pilocarpine rat model of focal epilepsy.

  Pharmaceutical research 20001101

• Vitamin E decreases valproic acid induced neural tube defects in mice.

  Neuroscience letters 20001013

• The safety of rapid valproic acid infusion.

  Epilepsia 20001001

• Valproate-induced tinnitus misinterpreted as psychotic symptoms.

  Southern medical journal 20001001

• Effects of combined administration of zonisamide and valproic acid or phenytoin to nitric oxide production, monoamines and zonisamide concentrations in the brain of seizure-susceptible EL mice.

  Brain research bulletin 20000915

• Influence of chronic barbiturate administration on sleep apnea after hypersomnia presentation: case study.

  Journal of psychiatry & neuroscience : JPN 20000901

• A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder.

  The Journal of clinical psychiatry 20000901

• Gabapentin in bipolar disorder: a placebo-controlled trial of adjunctive therapy. Gabapentin Bipolar Disorder Study Group.

  Bipolar disorders 20000901

• Fatal deterioration of neurological disease after orthotopic liver transplantation for valproic acid-induced liver damage.

  Pediatric transplantation 20000801

• Valproic acid-induced hyperammonemic encephalopathy with triphasic waves.

  Epilepsia 20000701

• Phenytoin poisoning after using Chinese proprietary medicines.

  Human & experimental toxicology 20000701

• Incidence of intravenous site reactions in neurotrauma patients receiving valproate or phenytoin.

  The Annals of pharmacotherapy 20000601

• [Valproic acid in prophylaxis of bipolar disorder. A case of valproate-induced encephalopathy].

  Der Nervenarzt 20000501

• Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice.

  Teratology 20000401

• Improved sexual function in three men taking lamotrigine for epilepsy.

  Southern medical journal 20000301

• Visual and auditory hallucinations with the association of bupropion and valproate.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 20000301

• Sodium valproate inhibits production of TNF-alpha and IL-6 and activation of NF-kappaB.

  Brain research 20000227

• A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy.

  Epilepsia 20000201

• Orthotopic liver transplantation with poor neurologic outcome in valproate-associated liver failure: a need for critical risk-benefit appraisal in the use of valproate.

  Transplantation proceedings 20000201

• Effects of anticonvulsants on local anaesthetic-induced neurotoxicity in rats.

  Pharmacology & toxicology 20000201

• Inappropriate liver transplantation in a child with Alpers-Huttenlocher syndrome misdiagnosed as valproate-induced acute liver failure.

  Pediatric transplantation 20000201

• Valproate-induced hyperammonemic encephalopathy in the presence of topiramate.

  Neurology 20000111

• Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected].

  Reproductive toxicology (Elmsford, N.Y.) 20000101

• Prenatal exposure of rats to valproic acid reproduces the cerebellar anomalies associated with autism.

  Neurotoxicology and teratology 20000101

• Pathomorphological changes in mouse liver and kidney during prolonged valproate administration.

  International journal of tissue reactions 20000101

• [Dementia and extrapyramidal problems caused by long-term valproic acid].

  Therapie 20000101

• Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity.

  The Journal of pharmacology and experimental therapeutics 19991201

• Intravenous valproate associated with significant hypotension in the treatment of status epilepticus.

  Journal of child neurology 19991201

• Lamotrigine as prophylaxis against steroid-induced mania.

  The Journal of clinical psychiatry 19991001

• [A case report of valproate encephalopathy].

  Rinsho shinkeigaku = Clinical neurology 19991001

• Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS) Group.

  Epilepsia 19990801

• Distinct features of seizures induced by cocaine and amphetamine analogs.

  European journal of pharmacology 19990721

• Fatal liver failure associated with valproate therapy in a patient with Friedreich's disease: review of valproate hepatotoxicity in adults.

  Epilepsia 19990701

• Cognitive dysfunction induced by phenytoin and valproate in rats: effect of nitric oxide.

  Indian journal of physiology and pharmacology 19990701

• The use of primidone in the treatment of refractory bipolar disorder.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 19990601

• Failure of periconceptual folic acid to prevent a neural tube defect in the offspring of a mother taking sodium valproate.

  Seizure 19990601

• Extrapyramidal symptoms associated with the adjunct of nortriptyline to a venlafaxine-valproic acid combination.

  International clinical psychopharmacology 19990501

• Clumsiness, confusion, coma, and valproate.

  Lancet (London, England) 19990424

• N-acetyl-beta-glucosaminidase and beta-galactosidase activity in children receiving antiepileptic drugs.

  Pediatric neurology 19990101

• [Encephalopathies caused by valproate].

  Fortschritte der Neurologie-Psychiatrie 19990101

• Assessment of colour vision in epileptic patients exposed to single-drug therapy.

  European neurology 19990101

• Contributions of dam and conceptus to differences in sensitivity to valproic acid among C57 black and SWV mice.

  Reproductive toxicology (Elmsford, N.Y.) 19990101

• Reversible parkinsonism induced by prolonged treatment with valproate.

  Journal of neurology 19981201

• Paradoxical response to valproic acid in a patient with a hypothalamic hamartoma.

  The Annals of pharmacotherapy 19981101

• Plasma glutathione peroxidase and its relationship to renal proximal tubule function.

  Molecular genetics and metabolism 19981101

• Responding for rewarding brain stimulation: cocaine and isradipine plus naltrexone.

  Pharmacology, biochemistry, and behavior 19981001

• Delirium and persistent dyskinesia induced by a lithium-neuroleptic interaction.

  Pharmacopsychiatry 19980901

• Pathological laughter following intravenous sodium valproate.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19980801

• Catatonia-like events after valproic acid with risperidone and sertraline.

  Neuropsychiatry, neuropsychology, and behavioral neurology 19980701

• Combined treatment of schizophrenic psychoses with haloperidol and valproate.

  Pharmacopsychiatry 19980701

• Valproate-induced epileptic tonic status.

  Seizure 19980601

• Hyperammonaemic encephalopathy after initiation of valproate therapy in unrecognised ornithine transcarbamylase deficiency.

  Journal of neurology, neurosurgery, and psychiatry 19980501

• Antiepileptic drugs and atypical evolution of idiopathic partial epilepsy.

  Pediatric neurology 19980501

• Cognitive effects of anticonvulsant monotherapy in elderly patients: a placebo-controlled study.

  Seizure 19980401

• Altered zinc metabolism contributes to the developmental toxicity of 2-ethylhexanoic acid, 2-ethylhexanol and valproic acid.

  Toxicology 19980220

• [Valproate induced parkinsonism].

  No to shinkei = Brain and nerve 19980101

• Reversible pseudoatrophy of the brain and mental deterioration associated with valproate treatment.

  Epilepsia 19980101

• [Morphological changes induced by valproate and its administration concomitant with folinic acid or S-adenosylmethionine in pregnant rats].

  Nutricion hospitalaria 19980101

• Antiepileptics and blood dyscrasias: a cohort study.

  Pharmacotherapy 19980101

• Reversible cortical atrophy and cognitive decline induced by valproic acid.

  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 19980101

• Multiorgan dysfunction and disseminated intravascular coagulation in children receiving lamotrigine and valproic acid.

  Neurology 19971101

• Cloning and characterization of chicken Paraxis: a regulator of paraxial mesoderm development and somite formation.

  Developmental biology 19970901

• Valproate-associated carnitine deficiency and malignant cerebral edema in the absence of hepatic failure.

  International journal of clinical pharmacology and therapeutics 19970901

• A male with fetal valproate syndrome and autism.

  Developmental medicine and child neurology 19970901

• Antinociceptive activity of sodium valproate in mice after chronic treatment.

  General pharmacology 19970901

• Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) triggered by valproate therapy.

  European journal of pediatrics 19970701

• Risperidone in the elderly: a pharmacoepidemiologic study.

  The Journal of clinical psychiatry 19970701

• Negative myoclonic status due to antiepileptic drug tapering: report of three cases.

  Epilepsia 19970701

• Strain-dependent alterations in the expression of folate pathway genes following teratogenic exposure to valproic acid in a mouse model.

  American journal of medical genetics 19970613

• Color vision tests for early detection of antiepileptic drug toxicity.

  Neurology 19970501

• Valproate-induced liver failure in one of two siblings with Alpers disease.

  Pediatric neurology 19970501

• Preclinical characterization of MDL 27,192 as a potential broad spectrum anticonvulsant agent with neuroprotective properties.

  Epilepsy research 19970401

• Postimplantation mouse embryos cultured in vitro. Assessment with whole-mount immunostaining and in situ hybridization.

  The International journal of developmental biology 19970401

• Hepatic encephalopathy associated with combined clozapine and divalproex sodium treatment.

  Journal of clinical psychopharmacology 19970401

• Dose-related thrombocytopenia and macrocytic anemia associated with valproate use in bipolar disorder.

  The Journal of clinical psychiatry 19970301

• [Reversible dementia due to valproic acid therapy].

  Nederlands tijdschrift voor geneeskunde 19970222

• Valproic-acid-associated pancreatitis and hepatic toxicity in children with endstage renal disease.

  Pediatric radiology 19970201

• Status epilepticus associated with the combination of valproic acid and clomipramine.

  Therapeutic drug monitoring 19970201

• Medium chain acyl-CoA dehydrogenase deficiency and fatal valproate toxicity.

  Pediatric neurology 19970201

• Extrapyramidal syndrome due to valproate administration as an adjunct to lithium in an elderly manic patient.

  International journal of geriatric psychiatry 19970201

• Biochemical basis of sodium valproate hepatotoxicity and renal tubular disorder: time dependence of peroxidative injury.

  Pharmacological research 19970201

• Linking etiologies in humans and animal models: studies of autism.

  Reproductive toxicology (Elmsford, N.Y.) 19970101

• Interaction of valproic acid with nonsteroidal antiinflammatory drugs mefenamic acid and fenoprofen in normal and uremic sera: lack of interaction in uremic sera due to the presence of endogenous factors.

  Therapeutic drug monitoring 19961201

• Valproic acid-induced changes in gene expression during neurulation in a mouse model.

  Teratology 19961201

• [Acute hepatic failure associated with valproic acid in children. Report of 3 cases].

  Arquivos de neuro-psiquiatria 19961201

• Clinical case report: multiple idiosyncratic adverse effects of antiepileptic drugs in trisomy 9p.

  The International journal of neuroscience 19961101

• Reversible parkinsonism and cognitive impairment with chronic valproate use.

  Neurology 19960901

• In vitro synergistic activity of ketoconazole with valproic acid against Candida species.

  Arzneimittel-Forschung 19960901

• Lithium-associated cognitive and functional deficits reduced by a switch to divalproex sodium: a case series.

  The Journal of clinical psychiatry 19960801

• Valproic acid-induced somite teratogenesis in the chick embryo: relationship with Pax-1 gene expression.

  Teratology 19960801

• Effect of L-carnitine supplementation on acute valproate intoxication.

  Epilepsia 19960701

• Antiepileptic drug treatment in pregnancy: drug side effects in the neonate and neurological outcome.

  Acta paediatrica (Oslo, Norway : 1992) 19960601

• Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.

  Methods and findings in experimental and clinical pharmacology 19960601

• Pharmacokinetic interactions and side effects resulting from concomitant administration of lithium and divalproex sodium.

  The Journal of clinical psychiatry 19960501

• A randomized comparison of divalproex oral loading versus haloperidol in the initial treatment of acute psychotic mania.

  The Journal of clinical psychiatry 19960401

• Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.

  Journal of pharmacological and toxicological methods 19960201

• Methionine reduces the valproic acid-induced spina bifida rate in mice without altering valproic acid kinetics.

  The Journal of nutrition 19960101

• Immunologically mediated chronic tubulo-interstitial nephritis caused by valproate therapy.

  Nephron 19960101

• Amphetamine and vigabatrin down regulate aromatic L-amino acid decarboxylase mRNA levels.

  Brain research. Molecular brain research 19960101

• Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect.

  Chemical research in toxicology 19960101

• Neuropsychiatric side effects related to treatment with felbamate.

  The Journal of neuropsychiatry and clinical neurosciences 19960101

• Sodium valproate augments spontaneous neural tube defects and axial skeletal malformations in TO mouse fetuses [corrected].

  Reproductive toxicology (Elmsford, N.Y.) 19960101

• Morphological features of encephalopathy after chronic administration of the antiepileptic drug valproate to rats. A transmission electron microscopic study of capillaries in the cerebellar cortex.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 19960101

• [Example of teratogen detection using a birth defects registry: depakine and spina bifida].

  Revue d'epidemiologie et de sante publique 19960101

• [Hemorrhagic shock and fulminant hepatic failure associated with valproate].

  Anales de medicina interna (Madrid, Spain : 1984) 19951201

• Attenuation by valproate of c-fos immunoreactivity in trigeminal nucleus caudalis induced by intracisternal capsaicin.

  British journal of pharmacology 19951201

• Oculogyric crisis induced by carbamazepine.

  Epilepsia 19951101

• Reversible dementia and apparent brain atrophy during valproate therapy.

  Annals of neurology 19951001

• Comparison of anticonvulsant efficacy of valproate during prolonged treatment with one and three daily doses or continuous ('controlled release') administration in a model of generalized seizures in rats.

  Epilepsia 19950901

• Pantothenic acid decreases valproic acid-induced neural tube defects in mice (I).

  Teratology 19950901

• Valproic acid-associated encephalopathy with coma.

  The American journal of psychiatry 19950801

• Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs.

  Epilepsia 19950801

• A clinically significant interaction between clozapine and valproate.

  Journal of clinical psychopharmacology 19950401

• Anticonvulsants suppress c-Fos protein expression in spinal cord neurons following noxious thermal stimulation.

  Experimental neurology 19950401

• Blood dyscrasias with carbamazepine and valproate: a pharmacoepidemiological study of 2,228 patients at risk.

  The American journal of psychiatry 19950301

• Negative myoclonus during valproate-related stupor. Neurophysiological evidence of a cortical non-epileptic origin.

  Electroencephalography and clinical neurophysiology 19950201

• Fluorinated analogues as mechanistic probes in valproic acid hepatotoxicity: hepatic microvesicular steatosis and glutathione status.

  Chemical research in toxicology 19950101

• [Fatal hepatic necrosis during treatment with sodium valproate].

  Cahiers d'anesthesiologie 19950101

• Anticonvulsants as a cause of Fanconi syndrome.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19950101

• Ethanol potentiates valproic acid-induced neural tube defects (NTDs) in mice due to toxicokinetic interactions.

  Reproductive toxicology (Elmsford, N.Y.) 19950101

• Valproic acid-induced rapid changes of met-enkephalin levels in rat brain. Probable association with abstinence behavior and anticonvulsant activity.

  Neuropeptides 19940901

• [Valproate related syndrome of inappropriate secretion of antidiuretic hormone (SIADH)--a case report].

  Rinsho shinkeigaku = Clinical neurology 19940901

• Valproate encephalopathy and hypocarnitinaemia in diabetic patients.

  Journal of neurology 19940801

• Bone marrow suppression induced by high dose valproic acid.

  Archives of disease in childhood 19940801

• Manic depressive disorder and lithium over the decades: the very educational case of Mrs. L.

  The Journal of clinical psychiatry 19940801

• Choreiform movements associated with the use of valproate.

  Archives of neurology 19940701

• A differential response to treatment with divalproex sodium in patients with intractable headache.

  Cephalalgia : an international journal of headache 19940601

• Concurrent use of clozapine and valproate in affective and psychotic disorders.

  The Journal of clinical psychiatry 19940601

• Haematological disturbances during long-term valproate therapy.

  European journal of pediatrics 19940501

• Acetazolamide appears effective in the management of valproate-induced tremor.

  Movement disorders : official journal of the Movement Disorder Society 19940501

• Fetal valproate syndrome: clinical and neuro-developmental features in two sibling pairs.

  Developmental medicine and child neurology 19940401

• Synthesis and evaluation of amino analogues of valproic acid.

  Pharmaceutical research 19940401

• Divalproex sodium in the treatment of aggressive behavior.

  Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 19940301

• Fatal fulminant hepatic failure due to sodium valproate in an adolescent.

  Indian pediatrics 19940201

• Pharmacodynamic interactions between phenytoin and valproate: individual and combined antiepileptic and neurotoxic actions in mice.

  Clinical neuropharmacology 19940201

• Medications for aggressiveness.

  Journal of the American Academy of Child and Adolescent Psychiatry 19940201

• Valproate-induced hepatic failure in a case of cytochrome c oxidase deficiency.

  European journal of pediatrics 19940201

• Exencephaly and axial skeletal malformations induced by maternal administration of sodium valproate in the MF1 mouse.

  Journal of craniofacial genetics and developmental biology 19940101

• Severe hepatotoxicity during valproate therapy: an update and report of eight new fatalities.

  Epilepsia 19940101

• Evaluation of the rat embryo culture system as a predictive test for human teratogens.

  Canadian journal of physiology and pharmacology 19940101

• Maternal carbamazepine and infant spina bifida.

  Reproductive toxicology (Elmsford, N.Y.) 19940101

• Effects of valproate and citrulline on ammonium-induced encephalopathy.

  Epilepsia 19940101

• Reversible valproate-induced extrapyramidal disorders.

  Epilepsia 19940101

• Anticonvulsant and neurotoxic activities of twelve analogues of valproic acid.

  Journal of pharmaceutical sciences 19931201

• Parkinsonian syndrome in childhood after sodium valproate administration.

  Clinical neuropharmacology 19931001

• Temporary abolition of seizure activity by flumazenil in a case of valproate-induced non-convulsive status epilepticus.

  Seizure 19930901

• Malformations, withdrawal manifestations, and hypoglycaemia after exposure to valproate in utero.

  Archives of disease in childhood 19930901

• Myoclonus and seizures in a patient with parkinsonism: induction by levodopa and its confirmation on SEPs.

  The Japanese journal of psychiatry and neurology 19930901

• Reversible Fanconi syndrome associated with valproate therapy.

  The Journal of pediatrics 19930801

• Sodium valproate-induced cardiovascular abnormalities in the Jcl:ICR mouse fetus: peak sensitivity of gestational day and dose-dependent effect.

  Teratology 19930801

• Valproic acid-induced truncal weakness and respiratory failure.

  The American journal of psychiatry 19930801

• Disabling tremor after lamotrigine with sodium valproate.

  Lancet (London, England) 19930717

• [Severe bone malformations in fetal valproic acid disease].

  Anales espanoles de pediatria 19930701

• Magnesium valproate attenuates hyperactivity induced by dexamphetamine-chlordiazepoxide mixture in rodents.

  European journal of pharmacology 19930624

• Unusual electronmicroscopic changes in valproate-associated liver failure.

  Lancet (London, England) 19930619

• Central analgesic effect of valproate in patients with epilepsy.

  Seizure 19930601

• Valproate-induced coma: case report and literature review.

  The Annals of pharmacotherapy 19930501

• Effects of the competitive NMDA receptor antagonist, CGP 37849, on anticonvulsant activity and adverse effects of valproate in amygdala-kindled rats.

  European journal of pharmacology 19930406

• Benzodiazepine amplification of valproate teratogenic effects in children of mothers with absence epilepsy.

  Neuropediatrics 19930401

• Psychiatric aspects of epilepsy in childhood treated with carbamazepine, phenytoin or sodium valproate: a random trial.

  Developmental medicine and child neurology 19930201

• Impairment of consciousness induced by valproate treatment following neurosurgical operation.

  Acta neurochirurgica 19930101

• Reduced bioavailability of moisture-exposed carbamazepine resulting in status epilepticus.

  Epilepsia 19930101

• Sodium valproate in the treatment of behavioral disturbance in dementia.

  Journal of geriatric psychiatry and neurology 19930101

• Trimethoprim potentiates valproic acid-induced neural tube defects (NTDs) in mice.

  Reproductive toxicology (Elmsford, N.Y.) 19930101

• Apparent valproic acid neurotoxicity in a hypoalbuminemic patient.

  The Annals of pharmacotherapy 19930101

• [Acute reversible liver necrosis after valproate therapy (immunologic hypersensitivity)].

  Padiatrie und Padologie 19930101

• Detection by HPLC-ICP of metallothionein in serum of an epileptic child with valproate-associated hepatotoxicity.

  Journal of trace elements and electrolytes in health and disease 19921201

• [Irreversible valproate-associated liver failure].

  Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde 19921201

• Prenatal diagnosis of spina bifida aperta after first-trimester valproate exposure.

  Prenatal diagnosis 19921101

• Methionine decreases the embryotoxicity of sodium valproate in the rat: in vivo and in vitro observations.

  Teratology 19921101

• Psychological effects of sodium valproate and carbamazepine in epilepsy.

  Archives of disease in childhood 19921101

• Carbamyl phosphate synthetase-1 deficiency discovered after valproic acid-induced coma.

  Acta neurologica Scandinavica 19920901

• Spina bifida aperta induced by valproic acid and by all-trans-retinoic acid in the mouse: distinct differences in morphology and periods of sensitivity.

  Teratology 19920801

• Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.

  Brain research. Developmental brain research 19920619

• [Disseminated intravascular coagulation in an epileptic infant under the treatment with sodium valproate].

  No to hattatsu = Brain and development 19920501

• Cocaine-induced respiratory depression and seizures are synergistic mechanisms of cocaine-induced death in rats.

  Annals of emergency medicine 19920501

• Spectrum of neural-tube defects in 34 infants prenatally exposed to antiepileptic drugs.

  Neurology 19920401

• The risk of spina bifida aperta after first-trimester exposure to valproate in a prenatal cohort.

  Neurology 19920401

• Alteration of embryonic folate metabolism by valproic acid during organogenesis: implications for mechanism of teratogenesis.

  Neurology 19920401

• Neuropsychiatric manifestations of defect in mitochondrial beta oxidation response to riboflavin.

  Journal of neurology, neurosurgery, and psychiatry 19920301

• Valproic acid-induced spina bifida: a mouse model.

  Teratology 19920201

• Methotrexate increases valproic acid-induced developmental toxicity, in particular neural tube defects in mice.

  Teratogenesis, carcinogenesis, and mutagenesis 19920101

• Suppression of experimental barbiturate and phenytoin withdrawal syndrome using valproate sodium.

  Folia medica 19920101

• Cognitive effects of antiepileptic drug discontinuation.

  Epilepsia 19920101

• Antiepileptic drugs delay the onset of seizures induced by aminophylline in conscious rats.

  Indian journal of physiology and pharmacology 19920101

• Treatment of valproic acid-associated hepatic failure with orthotopic liver transplantation.

  The Annals of pharmacotherapy 19920101

• Calcium valproate-induced uterine adenocarcinomas in Wistar rats.

  Toxicology 19920101

• Acute intermittent porphyria and epilepsy: safety of clonazepam.

  Epilepsia 19920101

• Valproate metabolites in serum and urine during antiepileptic therapy in children with infantile spasms: abnormal metabolite pattern associated with reversible hepatotoxicity.

  Epilepsia 19920101

• [Suspected convulsive side-effect of mefloquine (Lariam)].

  Der Nervenarzt 19911201

• Lack of attenuation of valproic acid-induced effects by folinic acid in rat embryos in vitro.

  Teratology 19910601

• On the development of alternative antiepileptic drugs. Lack of enantioselectivity of the anticonvulsant activity, in contrast to teratogenicity, of 2-n-propyl-4-pentenoic acid and 2-n-propyl-4-pentynoic acid, analogues of the anticonvulsant drug valproic acid.

  Die Naturwissenschaften 19910601

• Incidental microvesicular steatosis due to valproic acid anticonvulsant therapy.

  The American journal of gastroenterology 19910401

• State of stupor from valproic acid during chronic treatment: case report.

  Italian journal of neurological sciences 19910401

• [Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].

  Rinsho shinkeigaku = Clinical neurology 19910301

• Cutaneous vasculitis induced by sodium valproate.

  Lancet (London, England) 19910223

• [Acute fatal liver insufficiency due to valproic acid therapy].

  Schweizerische medizinische Wochenschrift 19910216

• Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.

  European journal of pharmacology 19910110

• Diurnal variation of folate concentrations in mouse embryo and plasma: the protective effect of folinic acid on valproic-acid-induced teratogenicity is time dependent.

  Reproductive toxicology (Elmsford, N.Y.) 19910101

• Treatment of panic disorder and benzodiazepine withdrawal with valproate.

  The Journal of neuropsychiatry and clinical neurosciences 19910101

• Sensorineural hearing loss: a reversible effect of valproic acid.

  Neurology 19901201

• Cognitive function in adult epileptic patients established on anticonvulsant monotherapy.

  Epilepsy research 19901201

• [Valproic acid and stupor].

  Nederlands tijdschrift voor geneeskunde 19901027

• Valproate-induced coma with ketosis and carnitine insufficiency.

  Archives of neurology 19901001

• Teratogenic effects of sodium valproate in the Jcl: ICR mouse fetus.

  Acta paediatrica Japonica : Overseas edition 19901001

• Valproic acid-associated encephalopathy.

  The Western journal of medicine 19900801

• Cognitive effects of long-term treatment with phenobarbital and valproic acid in school children.

  Acta neurologica Scandinavica 19900601

• Valproic acid and panic disorder.

  Canadian journal of psychiatry. Revue canadienne de psychiatrie 19900401

• Fatal hepatocerebral syndrome in siblings discordant for exposure to valproate.

  Epilepsia 19900101

• Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acid.

  Toxicology letters 19891001

• [Transient Parkinson syndrome and tremor caused by the use of sodium valproate].

  Nederlands tijdschrift voor geneeskunde 19890617

• Valproic acid, unlike other anticonvulsants, has no effect on methadone metabolism: two cases.

  The Journal of clinical psychiatry 19890601

• Valproic acid induction of coma in rats: synergism with NH4+ and pentobarbital.

  Metabolic brain disease 19890601

• Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons.

  Annals of neurology 19890601

• Valproate and spina bifida.

  BMJ (Clinical research ed.) 19890513

• Fetal valproate phenotype is recognisable by mid pregnancy.

  Journal of medical genetics 19890501

• Valproate and spina bifida.

  Lancet (London, England) 19890318

• Valproic acid prenatal exposure. Association with lipomyelomeningocele.

  Clinical pediatrics 19890201

• Effects of sodium valproate on development and social behaviour in the Mongolian gerbil.

  Neurotoxicology and teratology 19890101

• Comparison of the anticonvulsant activities of ethosuximide, valproate, and a new anticonvulsant, thiobutyrolactone.

  Epilepsia 19890101

• [Cerebral edema with hyperammonemia in valpromide poisoning. Manifestation in an adult, of a partial deficit in type I carbamylphosphate synthetase].

  Presse medicale (Paris, France : 1983) 19881105

• Lithium-induced downbeat nystagmus.

  Archives of neurology 19880901

• Kawasaki-like syndrome caused by carbamazepine.

  The Pediatric infectious disease journal 19880701

• Strain differences in the teratogenicity induced by sodium valproate in cultured mouse embryos.

  Teratology 19880701

• Valproic acid loading during intensive monitoring.

  Archives of neurology 19880601

• Glutathione status and the incidence of neural tube defects elicited by direct acting teratogens in vitro.

  Teratology 19880601

• [Reye-like syndrome following valproate therapy in an adult].

  Psychiatrie, Neurologie, und medizinische Psychologie 19880601

• [Acute hepatic steatosis. Description of a clinical case of sodium valproate-induced acute hepatic steatosis].

  La Clinica terapeutica 19880331

• Sodium-valproate-induced interstitial nephritis.

  Nephron 19880101

• [Experimental study of the antiepileptic activity of fenibut and its combinations with sodium valproate and aminooxyacetic acid].

  Farmakologiia i toksikologiia 19880101

• Amniotic fluid cholinesterase of valproate-induced exencephaly in the mouse: an animal model for prenatal diagnosis of neural tube defects.

  Archives of toxicology 19880101

• Clinical side effects of phenobarbital, primidone, phenytoin, carbamazepine, and valproate during monotherapy in children.

  Epilepsia 19880101

• Inhibition of aminophylline-induced convulsions in mice by antiepileptic drugs and other agents.

  European journal of pharmacology 19871215

• Bidirectional effects of beta-carbolines in reflex epilepsy.

  Brain research bulletin 19870901

• [Prenatal diagnosis of 4 cases of spina bifida in mothers treated with valproate].

  Journal de genetique humaine 19870801

• Clinical valproate toxicity induced by acetylsalicylic acid.

  Neurology 19870801

• Pseudoatrophy of the brain with valproic acid monotherapy.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19870801

• Valproic acid-induced neural tube defects: reduction by folinic acid in the mouse.

  Life sciences 19870706

• Camptocormia, a new side effect of sodium valproate.

  Epilepsy research 19870701

• [Fatal hepatic failure in a normally developed 5-year-old boy caused by VPA monotherapy].

  Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde 19870601

• [Unapparent course of pancreatitis with pseudocyst development and cholestatic jaundice in anticonvulsive therapy with valproate].

  Klinische Wochenschrift 19870504

• Diagnosis of argininosuccinic aciduria after valproic acid-induced hyperammonemia.

  Neurology 19870501

• A suspected case of late-onset sodium-valproate-induced hepatic failure.

  Neuropediatrics 19870501

• [Thrombopenia and erythroblastopenia in a 1-month-old infant treated with valproate].

  Annales de pediatrie 19870201

• Long-term treatment with sodium valproate: monitoring of venous ammonia concentrations and adverse effects.

  Therapeutic drug monitoring 19870101

• [Stuporous state in an epileptic treated with sodium valproate. Diagnostic problems].

  Acta neurologica Belgica 19870101

• Use of ethosuximide and valproate in the treatment of epilepsy.

  Neurologic clinics 19860801

• In-utero exposure to valproate and neural tube defects.

  Lancet (London, England) 19860614

• Valproic acid teratogenicity in mice after various administration and phenobarbital-pretreatment regimens: the parent drug and not one of the metabolites assayed is implicated as teratogen.

  Fundamental and applied toxicology : official journal of the Society of Toxicology 19860501

• Pharmacologic evaluation of various metabolites and analogs of valproic acid: teratogenic potencies in mice.

  Fundamental and applied toxicology : official journal of the Society of Toxicology 19860501

• Prenatal detection of a neural tube defect after fetal exposure to valproic acid.

  Obstetrics and gynecology 19860301

• Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats.

  Epilepsia 19860101

• Reversible valproic acid-induced dementia: a case report.

  Epilepsia 19860101

• GABAergic, dopaminergic and cholinergic interactions in perphenazine-induced catatonia in rats.

  Archives internationales de pharmacodynamie et de therapie 19851201

• Effects of inhibitors of GABA-transaminase on hole-board exploration and on temperature. Relation with effects on quasi-morphine abstinence behaviour induced by sodium dipropylacetate.

  Biochemical pharmacology 19851101

• Sodium valproate and brainstem energetics.

  Neurochemical research 19851001

• Teratogenic valproic acid concentrations: infusion by implanted minipumps vs conventional injection regimen in the mouse.

  Toxicology and applied pharmacology 19850915

• [State of confusion induced by valproic acid and reversed after administration of clonazepam].

  Revue d'electroencephalographie et de neurophysiologie clinique 19850901

• [Acute liver necrosis caused by valproate].

  Deutsche medizinische Wochenschrift (1946) 19850614

• Nocturnal enuresis associated with sodium valproate.

  Lancet (London, England) 19850427

• Valproic acid therapy and neural tube defects.

  Canadian Medical Association journal 19850415

• Valproic acid associated abnormalities of carnitine metabolism.

  Lancet (London, England) 19850406

• Sodium valproate 'encephalopathy': report of three cases with generalised epilepsy.

  Italian journal of neurological sciences 19850301

• Maternal epilepsy and birth defects: a case-control study in the Italian Multicentric Registry of Birth Defects (IPIMC).

  European journal of epidemiology 19850301

• [Encephalopathy with asterixis induced by sodium valproate. Role of hyperammonemia without hepatic insufficiency].

  Presse medicale (Paris, France : 1983) 19850216

• Etifoxine: evaluation of its anticonvulsant profile in mice in comparison with sodium valproate, phenytoin and clobazam.

  Arzneimittel-Forschung 19850101

• Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.

  Arzneimittel-Forschung 19850101

• The specific protective effect of diazepam and valproate against isoniazid-induced seizures is not correlated with increased GABA levels.

  Journal of neural transmission 19850101

• Rearrangement of valproate glucuronide in a patient with drug-associated hepatobiliary and renal dysfunction.

  Epilepsia 19850101

• Valproate and spina bifida.

  Lancet (London, England) 19841215

• Glycine potentiates the action of some anticonvulsant drugs in some seizure models.

  Neurochemical research 19841201

• Genetic influences on the central nervous system depressant and membrane-disordering actions of ethanol and sodium valproate.

  Molecular pharmacology 19841101

• Acute changes of blood ammonia may predict short-term adverse effects of valproic acid.

  Neurology 19841101

• The fetal valproate syndrome.

  American journal of medical genetics 19841101

• Pancreatitis associated with valproic acid therapy.

  American journal of diseases of children (1960) 19841001

• Spina bifida and in-utero exposure to valproate.

  Lancet (London, England) 19840818

• Comparative evaluation of anticonvulsant and toxic potencies of valproic acid and 2-en-valproic acid in different animal models of epilepsy.

  European journal of pharmacology 19840323

• Electroencephalographic alterations during intoxication with sodium valproate: a case report.

  Epilepsia 19840201

• Hyperammonemia and valproate-induced alterations of the state of consciousness. A report of 8 cases.

  European neurology 19840101

• Treatment of valproate tremors.

  Neurology 19831001

• Treatment of epileptic patients with valproic acid does not modify plasma and urine short-chain-fatty acids.

  Acta neurologica Scandinavica 19831001

• Safe readministration of valproate after an episode of hepatotoxicity.

  Annals of neurology 19830601

• Febrile seizures in epileptic chicks: the effects of phenobarbital, phenytoin and valproate.

  The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 19830501

• Valproic acid embryopathy?

  Neurology 19830201

• [Is valproic acid teratogenic?].

  Revue neurologique 19830101

• Reye-like syndrome associated with valproic acid.

  Brain & development 19830101

• [Role of hyperammonemia in stuporous states induced by sodium valproate].

  Revue neurologique 19830101

• [Alterations of the state of consciousness induced by valproic acid: 6 case reports].

  Rivista di patologia nervosa e mentale 19830101

• Sodium valproate: monotherapy and polytherapy.

  Epilepsia 19821201

• Valproic acid and spina bifida.

  Lancet (London, England) 19821113

• Decreased serum carnitine in valproate induced Reye syndrome.

  European journal of pediatrics 19821101

• Maternal valproic acid and congenital neural tube defects.

  Lancet (London, England) 19821023

• Stuporous states or coma induced by the rapid administration of high doses of sodium valproate.

  Italian journal of neurological sciences 19821001

• Dipropylacetate-induced quasi-morphine abstinence behaviour in the rat: participation of the locus coeruleus system.

  Brain research 19820916

• Comparative anticonvulsant activity and neurotoxicity of clobazam, diazepam, phenobarbital, and valproate in mice and rats.

  Epilepsia 19820801

• Stuporous episodes during treatment with sodium valproate: report of seven cases.

  Epilepsia 19820601

• Valproate tremors.

  Neurology 19820401

• Side effects of sodium valproate in monotherapy controlled by plasma levels: a study in 88 pediatric patients.

  Epilepsia 19820401

• Sodium valproate-induced hyperammonemia without clinical hepatic dysfunction.

  Neurology 19820201

• Febrile convulsions: intellectual progress in relation to anticonvulsant therapy and to recurrence of fits.

  Archives of disease in childhood 19820201

• Pure red cell aplasia associated with sodium valproate therapy.

  JAMA 19820101

• Sodium valproate versus phenobarbital in the prophylactic treatment of febrile convulsions in childhood.

  European journal of pediatrics 19811001

• Delirium induced by the competitive interaction between phenytoin and dipropylacetate.

  Journal of clinical psychopharmacology 19810501

• Valproic acid: a possible cause of proximal tubular renal syndrome.

  The Journal of pediatrics 19810301

• Asterixis associated with sodium valproate.

  Neurology 19810201

• [Stuporous states during treatment with sodium valproate. Pathogenetic hypotheses].

  Revue neurologique 19810101

• [Stupor due to sodium valproate. Immediate arousal after intravenous diazepam (author's transl)].

  Revue neurologique 19810101

• Fatal hepatic failure and sodium valproate.

  Lancet (London, England) 19801213

• Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin.

  Science (New York, N.Y.) 19801128

• Acute liver disease associated with sodium valproate.

  Lancet (London, England) 19801122

• Individualized patient assessment in the treatment of epilepsy with sodium valproate.

  Epilepsia 19800801

• Secondary hyperammonaemia: a possible mechanism for valproate encephalopathy.

  Lancet (London, England) 19800614

• Fatal Reye-like syndrome associated with valproic acid.

  Annals of neurology 19800401

• Sodium valproate and acute hepatic failure.

  Developmental medicine and child neurology 19800401

• Dipropylacetate and aminoaciduria.

  Journal of the neurological sciences 19800201

• Stupor following administration of valproic acid to patients receiving other antiepileptic drugs.

  Epilepsia 19791201

• Extrapyramidal syndrome with sodium valproate.

  British medical journal 19791027

• Valporic acid and coma.

  Neurology 19791001

• Tremor due to sodium valproate.

  Neurology 19790801

• Side effects of sodium valproate during long-term treatment in epilepsy.

  Acta neurologica Scandinavica 19790801

• Some aspects of the clinical use of clonazepam in refractory epilepsy.

  Clinical and experimental neurology 19790101

• Sodium valproate (Epilim) in epilepsy: a trial.

  The New Zealand medical journal 19781227

• Sodium valproate in the treatment of levodopa-induced dyskinesia.

  Journal of neurology, neurosurgery, and psychiatry 19780801

• [Disorders of hemostasis caused by dipropylacetate].

  MMW, Munchener medizinische Wochenschrift 19770121

• Di-n-propylacetic acid--profile of anticonvulsant activity in mice.

  Arzneimittel-Forschung 19760201