1070-19-5 | Carbonazidic acid,1,1-dimethylethyl ester

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Description

• Catalog Number: AD64678
• Chemical Name: Carbonazidic acid,1,1-dimethylethyl ester
• CAS Number: 1070-19-5
• Molecular Formula: C5H9N3O2
• Molecular Weight: 143.1439
• MDL Number: MFCD01742129
• SMILES: O=C(N=[N+]=[N-])OC(C)(C)C

Upstream Synthesis Route

1,1-Dimethylethyl carbonazidate, also known as tert-butyl carbonazidate, is a versatile compound widely used in chemical synthesis due to its unique reactivity and compatibility with various reaction conditions. This reagent serves as a valuable precursor for the introduction of azide functional groups into organic molecules. In organic synthesis, 1,1-Dimethylethyl carbonazidate is commonly employed in nucleophilic substitution reactions to introduce an azide group onto various substrates. This azide group can subsequently participate in azide-alkyne cycloaddition reactions, also known as "click chemistry," to form triazole linkages, a widely used strategy in medicinal chemistry, bioconjugation, and material science.Furthermore, 1,1-Dimethylethyl carbonazidate can also be utilized in transition metal-catalyzed coupling reactions, such as palladium-catalyzed cross-coupling reactions, to introduce azides onto aryl or alkyl halides. This allows for the synthesis of complex organic molecules with azide functionality in a precise and efficient manner. Overall, the application of 1,1-Dimethylethyl carbonazidate in chemical synthesis is instrumental in the construction of diverse chemical scaffolds, enabling the development of new materials, bioactive compounds, and pharmaceutical agents.