107099-99-0 | 2,5-Dimethoxyphenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$10.00	$7.00
5g	97%	in stock	$17.00	$12.00
10g	97%	in stock	$24.00	$17.00
25g	97%	in stock	$50.00	$35.00

Description

• Catalog Number: AB60472
• Chemical Name: 2,5-Dimethoxyphenylboronic acid
• CAS Number: 107099-99-0
• Molecular Formula: C8H11BO4
• Molecular Weight: 181.9815
• MDL Number: MFCD01318181
• SMILES: COc1ccc(c(c1)B(O)O)OC

Computed Properties

• Complexity: 153
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3

Upstream Synthesis Route

(2,5-Dimethoxyphenyl)boronic acid is a versatile compound widely used in chemical synthesis due to its unique properties and reactivity. This boronic acid derivative serves as a key building block in the synthesis of various organic compounds, particularly in the field of medicinal chemistry and drug development.One of the primary applications of (2,5-Dimethoxyphenyl)boronic acid is in Suzuki-Miyaura cross-coupling reactions. This reaction, catalyzed by palladium, enables the formation of carbon-carbon bonds between an aryl or vinyl boronic acid and an aryl or vinyl halide or pseudohalide. By utilizing (2,5-Dimethoxyphenyl)boronic acid as a coupling partner, chemists can efficiently synthesize biaryl compounds, which are prevalent motifs in pharmaceuticals, agrochemicals, and materials science.Moreover, (2,5-Dimethoxyphenyl)boronic acid can be employed in the functionalization of aromatic substrates through C-H activation reactions. In this process, the boronic acid derivative acts as a directing group, facilitating the introduction of various functional groups selectively at specific positions on the aromatic ring. This strategy offers a powerful tool for the late-stage modification of complex molecules, enabling the rapid diversification of chemical structures for drug discovery and material design.Overall, the application of (2,5-Dimethoxyphenyl)boronic acid in chemical synthesis showcases its significance as a valuable reagent for constructing intricate organic molecules with precise control over regioselectivity and functionality. By leveraging the unique reactivity of this compound, chemists can access a diverse array of target molecules with potential applications in pharmaceuticals, materials science, and agrochemicals.