1072811-67-6 | 4-Methoxycarbonylindole-2-boronic acid pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$82.00	$57.00
1g	98%	in stock	$219.00	$154.00
5g	98%	in stock	$902.00	$631.00
25g	95%	in stock	$3,744.00	$2,621.00

Description

• Catalog Number: AD64257
• Chemical Name: 4-Methoxycarbonylindole-2-boronic acid pinacol ester
• CAS Number: 1072811-67-6
• Molecular Formula: C16H20BNO4
• Molecular Weight: 301.1453
• MDL Number: MFCD11858381
• SMILES: COC(=O)c1cccc2c1cc([nH]2)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 437
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3

Upstream Synthesis Route

Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-4-carboxylate is a versatile compound widely used in chemical synthesis, particularly in the field of organic chemistry. This compound serves as an important building block for the development of various pharmaceuticals, agrochemicals, and materials due to its unique structural features and reactivity.One key application of Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-4-carboxylate is its role as a valuable substrate for Suzuki-Miyaura cross-coupling reactions. This powerful synthetic method allows for the formation of carbon-carbon bonds under mild conditions, enabling the efficient and selective synthesis of biaryl compounds. By utilizing Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-4-carboxylate in these reactions, chemists can access a diverse array of functionalized indole derivatives with high yields and excellent regioselectivity.Furthermore, this compound can be employed in the construction of complex molecular architectures through sequential transformations, enabling the rapid assembly of advanced intermediates for various natural product synthesis or medicinal chemistry endeavors. Its compatibility with a wide range of functional groups and its stability under a variety of reaction conditions make Methyl 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-4-carboxylate a valuable tool for synthetic chemists seeking to streamline their synthetic pathways and access novel chemical entities of interest.