1072944-22-9 | 6-Bromo-2-methylpyridine-3-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$55.00	$38.00
1g	98%	in stock	$112.00	$78.00
5g	98%	in stock	$413.00	$289.00
10g	98%	in stock	$758.00	$531.00
25g	98%	in stock	$1,535.00	$1,074.00

Description

• Catalog Number: AB55275
• Chemical Name: 6-Bromo-2-methylpyridine-3-boronic acid
• CAS Number: 1072944-22-9
• Molecular Formula: C6H7BBrNO2
• Molecular Weight: 215.8403
• MDL Number: MFCD09037490
• SMILES: OB(c1ccc(nc1C)Br)O

Computed Properties

• Complexity: 136
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

In chemical synthesis, (6-Bromo-2-methylpyridin-3-yl)boronic acid serves as a versatile building block that is commonly utilized in the creation of various organic compounds. This compound, characterized by its boronic acid moiety attached to a pyridine ring substituted with bromine and a methyl group, offers a valuable platform for constructing more complex molecules through the formation of carbon-carbon and carbon-heteroatom bonds.One of the primary applications of (6-Bromo-2-methylpyridin-3-yl)boronic acid lies in transition-metal catalyzed cross-coupling reactions, particularly Suzuki-Miyaura coupling. This process involves the reaction of the boronic acid derivative with an organic halide or pseudohalide in the presence of a palladium catalyst, resulting in the formation of a new carbon-carbon bond. By facilitating these cross-coupling reactions, (6-Bromo-2-methylpyridin-3-yl)boronic acid enables the efficient synthesis of biaryl compounds, which are prevalent in pharmaceuticals, agrochemicals, and materials chemistry.Furthermore, the boronic acid functionality in this compound offers the potential for further derivatization, allowing for the introduction of diverse functional groups and modifications to tailor the properties of the final product. This versatility makes (6-Bromo-2-methylpyridin-3-yl)boronic acid a valuable tool in the hands of synthetic chemists seeking to access a wide range of structurally complex molecules for various applications in the fields of drug discovery, materials science, and chemical research.