1072945-04-0 | 4-Chloromethylphenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$37.00	$26.00
1g	97%	in stock	$108.00	$76.00
5g	98%	in stock	$449.00	$315.00

Description

• Catalog Number: AD45562
• Chemical Name: 4-Chloromethylphenylboronic acid, pinacol ester
• CAS Number: 1072945-04-0
• Molecular Formula: C13H18BClO2
• Molecular Weight: 252.5448
• MDL Number: MFCD11053893
• SMILES: ClCc1ccc(cc1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 257
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

The compound 2-(4-(Chloromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane plays a crucial role in chemical synthesis as a versatile building block for the preparation of various functionalized organic compounds. Its unique structure containing a boron atom allows it to participate in diverse chemical reactions, particularly in Suzuki-Miyaura cross-coupling reactions.This compound can be utilized as a boronic acid derivative in the synthesis of biaryl compounds through palladium-catalyzed coupling reactions with aryl halides or pseudohalides. The presence of the chloromethyl group enhances the reactivity of the boronic acid, enabling efficient and selective carbon-carbon bond formation.Additionally, 2-(4-(Chloromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is employed in the construction of complex molecular structures in pharmaceutical and agrochemical research, making it a valuable tool for medicinal chemistry and material science. Its application extends to the preparation of OLED materials, ligands for catalysis, and advanced materials with tailored properties.Overall, this compound serves as a key intermediate in the synthesis of diverse organic molecules, providing chemists with a versatile and reliable building block for the efficient construction of complex molecular architectures.