1072945-67-5 | 3-(Cyclopropanesulfonamido)phenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$201.00	$141.00
5g	98%	in stock	$758.00	$531.00

Description

• Catalog Number: AD45560
• Chemical Name: 3-(Cyclopropanesulfonamido)phenylboronic acid
• CAS Number: 1072945-67-5
• Molecular Formula: C9H12BNO4S
• Molecular Weight: 241.0719
• MDL Number: MFCD10699613
• SMILES: OB(c1cccc(c1)NS(=O)(=O)C1CC1)O

Computed Properties

• Complexity: 336
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 4

Upstream Synthesis Route

The (3-(Cyclopropanesulfonamido)phenyl)boronic acid is a versatile compound widely used in chemical synthesis due to its unique reactivity and structural properties. This specific boronic acid derivative serves as a valuable building block in organic chemistry, particularly in the formation of carbon-carbon and carbon-heteroatom bonds.In organic synthesis, (3-(Cyclopropanesulfonamido)phenyl)boronic acid can participate in various reactions including Suzuki-Miyaura cross-coupling, Chan-Lam coupling, and Buchwald-Hartwig amination. These reactions enable the introduction of the phenylsulfonamide group onto diverse organic molecules, thereby expanding the chemical space for drug discovery and material science applications.Additionally, the cyclopropane moiety in the structure of this boronic acid derivative can serve as a masked reactive fragment, allowing for strategic transformations and subsequent functional group manipulations in complex molecule synthesis. Moreover, the boronic acid functionality provides a handle for selective derivatization through metal-catalyzed or metal-free coupling reactions, enabling the rapid generation of structurally diverse compounds with tailored properties.Overall, the (3-(Cyclopropanesulfonamido)phenyl)boronic acid offers a synthetic chemist a powerful tool for the construction of intricate molecular architectures with fine-tuned functionality, making it a valuable reagent in modern organic synthesis strategies.