1072945-69-7 | 4-Chloropyridine-3-boronic acid , HCl

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$280.00	$196.00
5g	98%	in stock	$1,058.00	$741.00

Description

• Catalog Number: AD45559
• Chemical Name: 4-Chloropyridine-3-boronic acid , HCl
• CAS Number: 1072945-69-7
• Molecular Formula: C5H6BCl2NO2
• Molecular Weight: 193.8236
• MDL Number: MFCD09972093
• SMILES: OB(c1cnccc1Cl)O.Cl

Computed Properties

• Complexity: 114
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

The (4-Chloropyridin-3-yl)boronic acid hydrochloride is a versatile chemical reagent commonly used in chemical synthesis. Its primary application lies in the field of organic chemistry, specifically in the synthesis of various pharmaceuticals, agrochemicals, and fine chemicals.This particular compound serves as a valuable building block in the creation of complex organic molecules due to its unique properties and reactivity. Its boronic acid functionality allows for convenient and selective cross-coupling reactions with various electrophiles, such as aryl halides, to form carbon-carbon bonds. This reaction, known as the Suzuki-Miyaura cross-coupling, is a powerful tool in modern organic synthesis and is widely employed in the pharmaceutical industry for the preparation of drug candidates.The (4-Chloropyridin-3-yl)boronic acid hydrochloride's ability to participate in these cross-coupling reactions makes it an essential reagent for the construction of biaryl structures, which are prevalent motifs in many bioactive compounds. Additionally, its halogen substituent can serve as a latent handle for further functionalization, allowing for the introduction of various chemical groups to tailor the properties of the final product.Overall, the (4-Chloropyridin-3-yl)boronic acid hydrochloride plays a crucial role in the strategic design and synthesis of organic molecules with diverse applications in the fields of medicine, agriculture, and materials science. Its utility in chemical synthesis underscores its importance as a valuable tool for chemists striving to access novel and complex molecular structures.