1072946-33-8 | 5-Chloro-2-methyl-4-(trifluoromethyl)phenylboronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	96%	in stock	$558.00	$391.00
250mg	96%	in stock	$1,101.00	$771.00

Description

• Catalog Number: AB69120
• Chemical Name: 5-Chloro-2-methyl-4-(trifluoromethyl)phenylboronic acid
• CAS Number: 1072946-33-8
• Molecular Formula: C8H7BClF3O2
• Molecular Weight: 238.3992
• MDL Number: MFCD11053801
• SMILES: OB(c1cc(Cl)c(cc1C)C(F)(F)F)O

Computed Properties

• Complexity: 224
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 15
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

(5-Chloro-2-methyl-4-(trifluoromethyl)phenyl)boronic acid is a valuable chemical compound used in a variety of chemical synthesis applications. As a boronic acid derivative, it serves as a versatile building block in the formation of carbon-carbon and carbon-heteroatom bonds through various reactions such as Suzuki-Miyaura coupling, Chan-Lam coupling, and Stille coupling.This specific boronic acid compound is particularly useful in the pharmaceutical industry for the synthesis of biologically active molecules, as well as in agrochemical and materials science research. Its unique structural properties, including the presence of both electron-withdrawing and electron-donating substituents, make it a valuable intermediate in the preparation of complex organic molecules.In organic synthesis, (5-Chloro-2-methyl-4-(trifluoromethyl)phenyl)boronic acid is commonly utilized as a key reagent for introducing the phenyltrifluoromethyl group into organic molecules, a moiety known for its application in medicinal chemistry and materials science. This compound's ability to participate in cross-coupling reactions enables the efficient construction of diverse molecular architectures with high regio- and stereoselectivity.Overall, the incorporation of (5-Chloro-2-methyl-4-(trifluoromethyl)phenyl)boronic acid into chemical synthesis strategies offers synthetic chemists a powerful tool for the efficient and precise creation of structurally complex and functionally diverse organic compounds.