1072946-46-3 | 5-(Aminomethyl)-2-fluorophenylboronic acid, HCl

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$139.00	$97.00
1g	98%	in stock	$299.00	$209.00
5g	98%	in stock	$1,070.00	$749.00

Description

• Catalog Number: AD45548
• Chemical Name: 5-(Aminomethyl)-2-fluorophenylboronic acid, HCl
• CAS Number: 1072946-46-3
• Molecular Formula: C7H10BClFNO2
• Molecular Weight: 205.4222
• MDL Number: MFCD11053811
• SMILES: NCc1ccc(c(c1)B(O)O)F.Cl

Computed Properties

• Complexity: 147
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 2

Upstream Synthesis Route

The (5-(Aminomethyl)-2-fluorophenyl)boronic acid hydrochloride is a versatile compound widely used in chemical synthesis. As a boronic acid derivative, this compound plays a crucial role in the field of organic chemistry due to its unique reactivity and compatibility with various functional groups. In particular, it is commonly employed as a key building block in Suzuki-Miyaura cross-coupling reactions, which enables the formation of carbon-carbon bonds under mild and selective conditions. This compound's ability to undergo palladium-catalyzed coupling reactions makes it an essential tool for the construction of complex organic molecules, such as pharmaceuticals, agrochemicals, and materials. Additionally, the presence of the fluorine atom in the aromatic ring provides enhanced properties, such as increased stability and potential for further functionalization, making it a valuable asset in the toolkit of synthetic chemists.