1072946-50-9 | 6-Chloro-2-methoxypyridine-3-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$19.00	$14.00
5g	96%	in stock	$76.00	$54.00
10g	96%	in stock	$141.00	$99.00
100g	96%	in stock	$1,317.00	$922.00

Description

• Catalog Number: AD79602
• Chemical Name: 6-Chloro-2-methoxypyridine-3-boronic acid
• CAS Number: 1072946-50-9
• Molecular Formula: C6H7BClNO3
• Molecular Weight: 187.3887
• MDL Number: MFCD11053817
• SMILES: COc1nc(Cl)ccc1B(O)O

Computed Properties

• Complexity: 149
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

The (6-Chloro-2-methoxypyridin-3-yl)boronic acid is a highly versatile compound widely utilized in chemical synthesis. As a boronic acid derivative, it serves as a valuable building block in the creation of various organic compounds. This specific compound offers a unique chloro and methoxy functional group combination on a pyridine ring, making it particularly suitable for diverse reactions in synthetic chemistry.In organic synthesis, (6-Chloro-2-methoxypyridin-3-yl)boronic acid is commonly used in Suzuki-Miyaura cross-coupling reactions. This reaction involves the coupling of an aryl or vinyl boronic acid derivative with an organic halide or pseudohalide, catalyzed by a palladium complex. The versatility of this coupling reaction allows for the formation of a wide range of biaryl compounds, which are essential building blocks in the pharmaceutical, agrochemical, and material science industries.Additionally, this compound can also participate in other important transformations such as metal-catalyzed C-H functionalization, C-N and C-O bond formation, and other cross-coupling reactions. Its unique structural features make it a valuable tool for creating complex molecular architectures with specific functional groups at precise positions.