1072951-45-1 | 5-Fluoroquinoline-8-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$101.00	$71.00
250mg	95%	in stock	$138.00	$97.00
1g	95%	in stock	$235.00	$164.00
5g	95%	in stock	$895.00	$626.00

Description

• Catalog Number: AB55250
• Chemical Name: 5-Fluoroquinoline-8-boronic acid
• CAS Number: 1072951-45-1
• Molecular Formula: C9H7BFNO2
• Molecular Weight: 190.9668
• MDL Number: MFCD11504850
• SMILES: OB(c1ccc(c2c1nccc2)F)O

Computed Properties

• Complexity: 205
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

The (5-Fluoroquinolin-8-yl)boronic acid is a versatile and valuable building block in chemical synthesis. Its application in organic chemistry is predominantly seen in transition metal-catalyzed cross-coupling reactions, specifically in Suzuki-Miyaura coupling. This compound serves as a key component in the formation of carbon-carbon bonds, which is crucial for the construction of complex molecular structures. By utilizing (5-Fluoroquinolin-8-yl)boronic acid as a reagent, chemists are able to access a wide array of substituted quinoline derivatives, which are significant in pharmaceutical and agrochemical research. Furthermore, the boronic acid moiety in this compound enables selective functionalization, making it a valuable tool for the synthesis of diverse chemical entities with specific properties and applications.