1072952-30-7 | 2-Picoline-5-boronic acid hydrate

Packsize	Purity	Availability	Price	Discounted Price
1g	96%	in stock	$203.00	$142.00
5g	96%	in stock	$760.00	$532.00

Description

• Catalog Number: AE10463
• Chemical Name: 2-Picoline-5-boronic acid hydrate
• CAS Number: 1072952-30-7
• Molecular Formula: C6H10BNO3
• Molecular Weight: 154.9595
• MDL Number: MFCD06657901
• SMILES: Cc1ccc(cn1)B(O)O.O

Computed Properties

• Complexity: 110
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

(6-Methylpyridin-3-yl)boronic acid hydrate is a versatile chemical compound that finds widespread application in organic synthesis. It serves as a valuable building block in the synthesis of various pharmaceuticals, agrochemicals, and materials due to its unique reactivity and functional group compatibility. In chemical synthesis, this compound acts as a boronic acid derivative, which allows it to participate in Suzuki-Miyaura cross-coupling reactions. This reaction is highly popular in organic chemistry for forming carbon-carbon bonds. The (6-Methylpyridin-3-yl)boronic acid hydrate can undergo this coupling reaction with aryl halides or pseudohalides in the presence of a palladium catalyst and base, leading to the formation of biaryl compounds. Furthermore, the boronic acid functionality of this compound enables it to undergo various transformations, such as oxidation to the corresponding phenol, palladium-catalyzed borylation reactions, and nucleophilic additions. These diverse reactivities make (6-Methylpyridin-3-yl)boronic acid hydrate a valuable tool for chemists involved in drug discovery, materials science, and other areas of organic chemistry research.