1073339-13-5 | 4-Chloro-2-fluoro-5-(methoxycarbonyl)phenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$29.00	$21.00
250mg	98%	in stock	$60.00	$42.00
5g	98%	in stock	$1,007.00	$705.00
10g	98%	in stock	$1,535.00	$1,074.00
25g	98%	in stock	$2,872.00	$2,010.00

Description

• Catalog Number: AE20244
• Chemical Name: 4-Chloro-2-fluoro-5-(methoxycarbonyl)phenylboronic acid, pinacol ester
• CAS Number: 1073339-13-5
• Molecular Formula: C14H17BClFO4
• Molecular Weight: 314.5448
• MDL Number: MFCD12026085
• SMILES: COC(=O)c1cc(B2OC(C(O2)(C)C)(C)C)c(cc1Cl)F

Computed Properties

• Complexity: 402
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3

Upstream Synthesis Route

Methyl 2-chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is a versatile compound widely used in chemical synthesis due to its unique reactivity and functional groups. This compound is commonly employed as a key building block in the synthesis of complex organic molecules, such as pharmaceutical intermediates and agrochemicals.One of the primary applications of Methyl 2-chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is in cross-coupling reactions, especially in palladium-catalyzed Suzuki-Miyaura couplings. By utilizing the boron moiety as a handle for selective cross-coupling reactions, this compound enables the introduction of diverse functional groups into the target molecules with high efficiency and selectivity. This feature makes it a valuable tool for synthetic chemists working on the design and synthesis of complex organic compounds.Furthermore, the presence of the ester functionality in Methyl 2-chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate allows for further derivatization through traditional organic transformations, expanding its utility in chemical synthesis. Overall, this compound plays a critical role in modern organic synthesis strategies, enabling the construction of intricate molecular architectures with strategic control over regioselectivity and functional group compatibility.