1073353-44-2 | 3-Chloromethylphenylboronic acid pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$27.00	$19.00
1g	98%	in stock	$71.00	$50.00
5g	98%	in stock	$197.00	$138.00

Description

• Catalog Number: AD45389
• Chemical Name: 3-Chloromethylphenylboronic acid pinacol ester
• CAS Number: 1073353-44-2
• Molecular Formula: C13H18BClO2
• Molecular Weight: 252.5448
• MDL Number: MFCD11053847
• SMILES: ClCc1cccc(c1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 265
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 17
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2

Upstream Synthesis Route

2-(3-(Chloromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a versatile compound widely used in chemical synthesis as a key building block for the creation of various organic molecules. This boronic ester derivative is particularly valued for its ability to undergo efficient Suzuki-Miyaura cross-coupling reactions, a powerful tool in modern organic synthesis. By serving as a coupling partner in this reaction, it enables the formation of carbon-carbon bonds between aryl and alkyl groups, thereby facilitating the construction of complex molecular structures with high efficiency and precision. The presence of the chloromethyl and tetramethyl groups in the molecule enhances its stability and reactivity, making it a valuable reagent in the hands of synthetic chemists aiming to access diverse chemical space for the development of pharmaceuticals, agrochemicals, materials, and other fine chemicals.