1073353-89-5 | 2-Fluoro-4-nitrophenylboronic acid, pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$14.00	$10.00
250mg	97%	in stock	$22.00	$16.00
1g	97%	in stock	$59.00	$42.00
5g	97%	in stock	$212.00	$149.00

Description

• Catalog Number: AE10416
• Chemical Name: 2-Fluoro-4-nitrophenylboronic acid, pinacol ester
• CAS Number: 1073353-89-5
• Molecular Formula: C12H15BFNO4
• Molecular Weight: 267.0612
• MDL Number: MFCD09264075
• SMILES: Fc1cc(ccc1B1OC(C(O1)(C)C)(C)C)[N+](=O)[O-]

Computed Properties

• Complexity: 355
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1

Upstream Synthesis Route

The 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane plays a crucial role in chemical synthesis as a versatile building block. Its unique structure containing a boron atom bonded to a phenyl ring with fluorine and nitro functional groups offers opportunities for diverse chemical transformations. In organic synthesis, 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is commonly used as a boronic ester reagent for palladium-catalyzed cross-coupling reactions. It can participate in Suzuki-Miyaura and other related coupling reactions to form carbon-carbon bonds efficiently. This compound facilitates the construction of complex molecular structures in drug discovery, material science, and agrochemical research.Furthermore, 2-(2-Fluoro-4-nitrophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane serves as a valuable component in the synthesis of pharmaceutical intermediates, natural product derivatives, and functional materials. Its ability to undergo selective transformations under mild reaction conditions makes it an attractive choice for chemists designing innovative synthetic routes.Overall, this compound's significance lies in its role as a fundamental synthetic tool that enables the creation of novel molecules with tailored properties and functionalities for various applications in the field of organic chemistry.