1073354-66-1 | 4-Formyl-2-methylphenylboronic acid pinacol ester

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$55.00	$38.00
1g	98%	in stock	$145.00	$102.00
5g	98%	in stock	$511.00	$358.00

Description

• Catalog Number: AB65318
• Chemical Name: 4-Formyl-2-methylphenylboronic acid pinacol ester
• CAS Number: 1073354-66-1
• Molecular Formula: C14H19BO3
• Molecular Weight: 246.1099
• MDL Number: MFCD08669583
• SMILES: O=Cc1ccc(c(c1)C)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 311
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2

Upstream Synthesis Route

3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde, a specialized compound in chemical synthesis, serves as a valuable building block in the creation of complex organic molecules. Its unique structure, featuring a boronic ester and aldehyde functional groups, enables it to participate in a variety of important reactions, particularly in the field of organic chemistry.One significant application of 3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde lies in the Suzuki-Miyaura cross-coupling reaction, a powerful tool for the formation of carbon-carbon bonds. In this process, the boronic ester moiety of the compound undergoes a palladium-catalyzed coupling with an aryl halide or pseudohalide, leading to the formation of a new carbon-carbon bond. This reaction is widely used in the synthesis of pharmaceuticals, agrochemicals, and materials science.Furthermore, the aldehyde group in 3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde can participate in various transformations, such as nucleophilic addition reactions, enabling the introduction of additional functional groups or further derivatization of the molecule. This versatility makes the compound a valuable intermediate in the synthesis of more complex organic compounds.Overall, the strategic placement of both boronic ester and aldehyde functional groups in 3-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde makes it a versatile and indispensable tool in chemical synthesis, facilitating the construction of diverse organic molecules with potential applications in various industries.