1074-59-5 | 3-(Imidazol-4-yl)propionic acid

Packsize	Purity	Availability	Price	Discounted Price
10mg	95%	in stock	$14.00	$10.00
50mg	95%	in stock	$37.00	$26.00
100mg	95%	in stock	$42.00	$29.00
250mg	95%	in stock	$59.00	$41.00
1g	95%	in stock	$179.00	$125.00
5g	95%	in stock	$760.00	$532.00
10g	95%	in stock	$1,319.00	$923.00

Description

• Catalog Number: AD45149
• Chemical Name: 3-(Imidazol-4-yl)propionic acid
• CAS Number: 1074-59-5
• Molecular Formula: C6H8N2O2
• Molecular Weight: 140.1399
• MDL Number: MFCD00237415
• SMILES: OC(=O)CCc1c[nH]cn1
• NSC Number: 66737

Computed Properties

• Complexity: 127
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: -0.3

Upstream Synthesis Route

3-(1H-Imidazol-4-yl)propanoic acid is a versatile compound commonly used in chemical synthesis for various applications. One of the key uses of this compound is as a building block in the synthesis of pharmaceutical agents and bioactive molecules. Its imidazole moiety imparts unique properties to the compound, making it valuable in the development of drug candidates targeting biological receptors and enzymes.In organic synthesis, 3-(1H-Imidazol-4-yl)propanoic acid serves as a precursor for the preparation of imidazole derivatives, which are important in medicinal chemistry. By functionalizing the carboxylic acid group or modifying the imidazole ring, chemists can create a diverse array of compounds with potential pharmaceutical activity.Furthermore, this compound can be utilized as a ligand in coordination chemistry, forming complexes with transition metals for catalytic applications. Its ability to chelate metal ions enables 3-(1H-Imidazol-4-yl)propanoic acid to participate in various metal-mediated reactions, such as cross-coupling reactions and metal-catalyzed transformations.Overall, 3-(1H-Imidazol-4-yl)propanoic acid plays a crucial role in the design and synthesis of biologically active molecules and functional materials, highlighting its significance in chemical research and drug discovery.

Literature

• Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.

  European journal of medicinal chemistry 20110501

• Structure based design of novel inhibitors for histidinol dehydrogenase from Geotrichum candidum.

  Bioorganic & medicinal chemistry letters 20100701