1074-86-8 | 4-Formylindole

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$8.00	$5.00
5g	98%	in stock	$18.00	$12.00
10g	98%	in stock	$32.00	$22.00
25g	98%	in stock	$78.00	$54.00

Description

• Catalog Number: AB50154
• Chemical Name: 4-Formylindole
• CAS Number: 1074-86-8
• Molecular Formula: C9H7NO
• Molecular Weight: 145.158
• MDL Number: MFCD01632221
• SMILES: O=Cc1cccc2c1cc[nH]2
• NSC Number: 337264

Computed Properties

• Complexity: 158
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.2

Upstream Synthesis Route

Indole-4-carboxaldehyde is a versatile compound widely used in chemical synthesis due to its unique properties and reactivity. This compound serves as a key building block for the synthesis of various indole derivatives, which are important structural motifs found in many biologically active molecules, pharmaceuticals, and natural products.In chemical synthesis, Indole-4-carboxaldehyde can undergo diverse transformations to introduce functional groups at different positions on the indole ring. Its aldehyde group can participate in various reactions such as nucleophilic addition, condensation, and reduction, allowing for the formation of a wide range of indole derivatives with tailored properties. Additionally, the presence of the carboxyl group provides an anchoring point for further derivatization, enabling the modification of indole-4-carboxaldehyde to suit specific synthetic needs.Furthermore, Indole-4-carboxaldehyde exhibits good stability under a variety of reaction conditions, making it a reliable precursor for the synthesis of complex molecules. Its compatibility with different reagents and reaction conditions makes it a valuable tool for organic chemists in the design and construction of novel compounds with potential applications in drug discovery, material science, and agrochemicals.

Literature

• One-pot synthesis of 2-substituted indoles from 2-aminobenzyl phosphonium salts. A formal total synthesis of arcyriacyanin A.

  Organic letters 20080717