1082949-68-5 | Ly2584702 tosylate

Packsize	Purity	Availability	Price	Discounted Price
1mg	98+%	in stock	$9.00	$6.00
5mg	98+%	in stock	$11.00	$8.00
10mg	98+%	in stock	$17.00	$12.00
50mg	98+%	in stock	$56.00	$39.00
100mg	98+%	in stock	$94.00	$66.00

Description

• Catalog Number: AE11440
• Chemical Name: Ly2584702 tosylate
• CAS Number: 1082949-68-5
• Molecular Formula: C28H27F4N7O3S
• Molecular Weight: 617.6177
• MDL Number: MFCD29054739
• SMILES: Cn1cc(nc1C1CCN(CC1)c1ncnc2c1cn[nH]2)c1ccc(c(c1)C(F)(F)F)F.Cc1ccc(cc1)S(=O)(=O)O

Computed Properties

• Complexity: 851
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 43
• Hydrogen Bond Acceptor Count: 12
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4

Upstream Synthesis Route

LY2584702 Tosylate is a valuable compound utilized in chemical synthesis for its unique properties and applications. As a potent kinase inhibitor, it plays a crucial role in inhibiting the activity of various kinases within biological systems. This interference with kinase activity is particularly beneficial in studies focusing on signal transduction pathways and cellular processes. In chemical synthesis, LY2584702 Tosylate serves as a versatile building block for creating intricate molecular structures and designing novel bioactive compounds. Its compatibility with a wide range of reaction conditions and its ability to modulate kinase functions make it an indispensable tool for researchers and chemists alike. By incorporating LY2584702 Tosylate into synthesis pathways, scientists can explore new ways to manipulate cellular signaling cascades and develop innovative therapeutic agents with potential applications in drug discovery and biotechnology.

Literature

• A phase I trial of LY2584702 tosylate, a p70 S6 kinase inhibitor, in patients with advanced solid tumours.

  European journal of cancer (Oxford, England : 1990) 20140301

• A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours.

  European journal of cancer (Oxford, England : 1990) 20140301