1083168-84-6 | 2-Methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine

Packsize	Purity	Availability	Price	Discounted Price
100mg	96%	in stock	$110.00	$77.00
250mg	96%	in stock	$161.00	$113.00
1g	96%	in stock	$398.00	$279.00

Description

• Catalog Number: AD66368
• Chemical Name: 2-Methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridine
• CAS Number: 1083168-84-6
• Molecular Formula: C13H20BNO3
• Molecular Weight: 249.1138
• MDL Number: MFCD12923399
• SMILES: COc1ncc(cc1B1OC(C(O1)(C)C)(C)C)C

Computed Properties

• Complexity: 293
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2

Upstream Synthesis Route

2-Methoxy-5-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, often referred to simply as $name$, serves as a versatile reagent in chemical synthesis due to its unique structural features. This compound finds significant utility in transition-metal-catalyzed cross-coupling reactions, particularly in palladium-catalyzed coupling reactions. When employed as a ligand in such reactions, $name$ facilitates the formation of carbon-carbon and carbon-heteroatom bonds with high efficiency and selectivity. In addition, its boron functionality enables selective transformations, leading to the synthesis of complex organic molecules and pharmaceutical intermediates with enhanced control over regioselectivity and stereoselectivity. Furthermore, the presence of the pyridine moiety enhances the reactivity and stability of the resulting metal complexes, making $name$ a valuable tool for the construction of challenging molecular architectures in modern organic synthesis strategies.