1083326-46-8 | 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$40.00	$28.00
1g	97%	in stock	$86.00	$61.00
5g	97%	in stock	$303.00	$213.00

Description

• Catalog Number: AD77825
• Chemical Name: 2-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)acetamide
• CAS Number: 1083326-46-8
• Molecular Formula: C11H18BN3O3
• Molecular Weight: 251.0899
• MDL Number: MFCD16660236
• SMILES: NC(=O)Cn1ncc(c1)B1OC(C(O1)(C)C)(C)C

Computed Properties

• Complexity: 332
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3

Upstream Synthesis Route

The compound 1H-Pyrazole-1-acetamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- is a valuable reagent in chemical synthesis due to its versatile applications. It serves as a crucial building block in the synthesis of various organic compounds, particularly in the formation of complex heterocyclic structures.One key application of this compound is in cross-coupling reactions, specifically in Suzuki-Miyaura couplings. By utilizing the boron-containing moiety, it can participate in palladium-catalyzed coupling reactions with suitable aryl or vinyl halides. This enables the formation of new carbon-carbon bonds, facilitating the synthesis of diverse chemical compounds with enhanced functionalities.Furthermore, the presence of the pyrazole ring in the molecule enhances its reactivity and compatibility in various synthetic transformations. This allows for the efficient construction of biologically active molecules, pharmaceutical intermediates, and functional materials through controlled and selective modification of the pyrazole scaffold.Overall, the strategic incorporation of 1H-Pyrazole-1-acetamide, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- in chemical synthesis enables chemists to access a wide range of structurally diverse compounds with tailored properties, making it an indispensable tool in modern organic synthesis.