1089283-49-7 | GSK1904529A

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$42.00	$29.00
5mg	95%	in stock	$150.00	$105.00
10mg	95%	in stock	$249.00	$174.00
25mg	95%	in stock	$462.00	$323.00

Description

• Catalog Number: AE11232
• Chemical Name: GSK1904529A
• CAS Number: 1089283-49-7
• Molecular Formula: C44H47F2N9O5S
• Molecular Weight: 851.9631
• MDL Number: MFCD17010271
• SMILES: COc1cc(N2CCC(CC2)N2CCN(CC2)S(=O)(=O)C)c(cc1Nc1nccc(n1)c1c(nc2n1cccc2)c1ccc(c(c1)C(=O)Nc1c(F)cccc1F)OC)CC

Computed Properties

• Complexity: 1530
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 61
• Hydrogen Bond Acceptor Count: 14
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 12
• XLogP3: 6.8

Upstream Synthesis Route

GSK1904529A is a versatile chemical compound that finds wide application in the field of chemical synthesis. Through its unique properties and reactivity, this compound serves as a valuable building block in the creation of various organic molecules. Its ability to undergo specific reactions under controlled conditions makes it a key component in the preparation of complex molecular structures. Chemists utilize GSK1904529A in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals, where precise control over molecular configuration is critical. This compound offers a strategic advantage in designing and developing new compounds with enhanced properties, thus driving innovation in the synthesis of diverse chemical products.

Literature

• Identification of potent Yes1 kinase inhibitors using a library screening approach.

  Bioorganic & medicinal chemistry letters 20130801

• Antitumor activity of GSK1904529A, a small-molecule inhibitor of the insulin-like growth factor-I receptor tyrosine kinase.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20090501

• Discovery and optimization of imidazo[1,2-a]pyridine inhibitors of insulin-like growth factor-1 receptor (IGF-1R).

  Bioorganic & medicinal chemistry letters 20090201