109-64-8 | 1,3-Dibromopropane

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$18.00	$13.00
100g	98%	in stock	$45.00	$31.00
500g	98%	in stock	$139.00	$97.00

Description

• Catalog Number: AB43136
• Chemical Name: 1,3-Dibromopropane
• CAS Number: 109-64-8
• Molecular Formula: C3H6Br2
• Molecular Weight: 201.8877
• MDL Number: MFCD00000255
• SMILES: BrCCCBr
• NSC Number: 62663

Computed Properties

• Complexity: 12.4
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 5
• Rotatable Bond Count: 2
• XLogP3: 2.4

Upstream Synthesis Route

1,3-Dibromopropane, also known as Trimethylene dibromide, is a valuable compound in chemical synthesis due to its versatile reactivity and applications. As a halogenated organic molecule, 1,3-Dibromopropane is commonly used as a starting material in the synthesis of various organic compounds, particularly in the production of pharmaceuticals, agrochemicals, and fine chemicals.One of the key applications of 1,3-Dibromopropane in chemical synthesis is its role as a bifunctional alkylating agent. The presence of two bromine atoms on the propane chain allows for selective alkylation reactions with nucleophilic compounds. This property makes 1,3-Dibromopropane an essential building block in the synthesis of more complex organic molecules, such as amino acids, heterocycles, and advanced materials.Furthermore, 1,3-Dibromopropane can undergo substitution reactions, such as nucleophilic substitution and elimination reactions, leading to the formation of diverse chemical functionalities. Its reactivity and specificity in these reactions make it a valuable tool for chemists to introduce specific functional groups into their target molecules with precision and control.Overall, the application of 1,3-Dibromopropane in chemical synthesis offers chemists a powerful tool for creating new compounds, modifying existing molecules, and advancing research in various fields of organic chemistry. Its versatility and reactivity make it a valuable reagent for designing and synthesizing novel materials with potential applications in medicine, agriculture, and industry.

Literature

• Structure and activity of DmmA, a marine haloalkane dehalogenase.

  Protein science : a publication of the Protein Society 20120201

• Development of tyrosine-based radiotracer 99mTc-N4-Tyrosine for breast cancer imaging.

  Journal of biomedicine & biotechnology 20120101

• Synthesis and evaluation of a series of 2-substituted-5-thiopropylpiperazine (piperidine)-1,3,4-oxadiazoles derivatives as atypical antipsychotics.

  PloS one 20120101

• A sensitive method for rapid detection of alkyl halides and dehalogenase activity using a multistep enzyme assay.

  AMB Express 20120101

• Real-time probing of structural dynamics by interaction between chromophores.

  The journal of physical chemistry. A 20111110

• 1,10-Phenanthrolinium ionic liquid crystals.

  Langmuir : the ACS journal of surfaces and colloids 20110301

• Synthesis and evaluation of amino acid-based radiotracer 99mTc-N4-AMT for breast cancer imaging.

  Journal of biomedicine & biotechnology 20110101

• Synthesis and Biological Evaluation of New 3-Phenyl-1-[(4-arylpiperazin-1-yl)alkyl]-piperidine-2,6-diones.

  Scientia pharmaceutica 20110101

• 6,7-Dihydro-5H-1,4-diazepino[1,2,3,4-lmn][1,10]phenanthroline-4,8-diium tris-(thio-cyanato-κN)cuprate(I).

  Acta crystallographica. Section E, Structure reports online 20101001

• 4,4'-(Propane-1,3-diyldi-oxy)dibenz-aldehyde.

  Acta crystallographica. Section E, Structure reports online 20100701

• Synthesis of 1,3-azaphosphol-2-ones. Crystal and molecular structures of [SP-4-2]-dichlorobis(3-phenyl-1,3-dihydrobenzo[1,3]azaphosphol-2-one-P)palladium(II) and its chloro(methyl)platinum(II) analogue.

  Dalton transactions (Cambridge, England : 2003) 20100107

• Novel gemini cationic surfactants based on N, N-dimethyl fatty hydrazide and 1,3-dibromopropane: synthesis, evaluation of surface and antimicrobial properties.

  Journal of oleo science 20100101

• 2-(3-Bromo-prop-yl)isoindoline-1,3-dione.

  Acta crystallographica. Section E, Structure reports online 20091101

• Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate.

  Nature chemical biology 20091001

• Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.

  ChemMedChem 20090803

• Physicochemical and biological characterization of novel macrocycles derived from o-phthalaldehyde.

  European journal of medicinal chemistry 20090601

• 1-(3-Bromo-prop-yl)-4-(2-pyrid-yl)-1H-1,2,3-triazole.

  Acta crystallographica. Section E, Structure reports online 20090501

• Bis[2-(3-bromo-prop-oxy)-5-methyl-phen-yl]methane.

  Acta crystallographica. Section E, Structure reports online 20090401

• Search for inhibitors of bacterial and human protein kinases among derivatives of diazepines[1,4] annelated with maleimide and indole cycles.

  Journal of medicinal chemistry 20081225

• Wave packet simulation of nonadiabatic dynamics in highly excited 1,3-dibromopropane.

  The journal of physical chemistry. A 20081023

• 1,3-Bis[5-(2-pyrid-yl)-1H-tetra-zol-1-yl]propane.

  Acta crystallographica. Section E, Structure reports online 20080701

• 1,3-Bis[4-(4-pyrid-yl)pyrimidin-2-ylsulfan-yl]propane.

  Acta crystallographica. Section E, Structure reports online 20080501

• X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579.

  Biochimica et biophysica acta 20080201

• Hepatotoxic and immunotoxic effects produced by 1,3-dibromopropane and its conjugation with glutathione in female BALB/c mice.

  Journal of toxicology and environmental health. Part A 20070801

• Effect of alterations of key active site residues in O6-alkylguanine-DNA Alkyltransferase on its ability to modulate the genotoxicity of 1,2-dibromoethane.

  Chemical research in toxicology 20070101

• Photodissociation study of 1,3-dibromopropane at 234 nm via an ion velocity imaging technique.

  The journal of physical chemistry. A 20051215

• Regioselective N-functionalization of tetraazacycloalkanes.

  The Journal of organic chemistry 20050902

• Non-covalent interaction between procyanidins and apple cell wall material. Part III: Study on model polysaccharides.

  Biochimica et biophysica acta 20050830

• Vibrational spectrum, ab initio calculation, conformational equilibria and torsional modes of 1,3-dibromopropane.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050501

• Susceptibility of newborn rats to hepatotoxicity of 1,3-dibromopropane and 1,1,2,2-tetrabromoethane, compared with young rats.

  The Journal of toxicological sciences 20050201

• Heteronuclear selective refocusing 2D NMR experiments for the spectral analysis of enantiomers in chiral oriented solvents.

  Magnetic resonance in chemistry : MRC 20040701

• Steady-state and pre-steady-state kinetic analysis of halopropane conversion by a rhodococcus haloalkane dehalogenase.

  Biochemistry 20030708

• The synthesis of carboacycles derived from B,B'-bis(aryl) derivatives of icosahedral ortho-carborane.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030616

• Imidazopyridinium and pyridopyrimidium bromides: synthesis and hydrolysis.

  The Journal of organic chemistry 20020405

• Preparation of new nitrogen-bridged heterocycles. 51. Syntheses and structures of compounds having two indolizine nuclei in a molecule.

  Chemical & pharmaceutical bulletin 20011101