109-70-6 | 1-Bromo-3-chloropropane

Packsize	Purity	Availability	Price	Discounted Price
25g	99%	in stock	$21.00	$15.00
100g	99%	in stock	$26.00	$18.00
250g	99%	in stock	$29.00	$21.00
500g	99%	in stock	$50.00	$35.00

Description

• Catalog Number: AB58059
• Chemical Name: 1-Bromo-3-chloropropane
• CAS Number: 109-70-6
• Molecular Formula: C3H6BrCl
• Molecular Weight: 157.4367
• MDL Number: MFCD00000998
• SMILES: ClCCCBr
• NSC Number: 9183

Computed Properties

• Complexity: 16.4
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 5
• Rotatable Bond Count: 2
• XLogP3: 1.9

Upstream Synthesis Route

1-Bromo-3-chloropropane is a valuable chemical compound frequently utilized in various chemical synthesis processes. Its versatile nature and unique properties make it an essential building block in the creation of numerous organic compounds. This compound is commonly employed as an alkylating agent in organic reactions, where it participates in substitution and elimination reactions to introduce the 1-bromo-3-chloropropane functional group into complex molecules.In chemical synthesis, 1-Bromo-3-chloropropane acts as a crucial intermediate for the production of different organic compounds, such as pharmaceuticals, agrochemicals, and specialty chemicals. Its ability to serve as a reactant in various chemical transformations, including nucleophilic substitution, makes it an indispensable tool for organic chemists seeking to modify molecular structures and create new compounds with specific properties. The unique combination of a bromine and chlorine atom in its structure enhances its reactivity and selectivity in a wide range of chemical reactions, allowing for precise control over the synthetic process.Furthermore, 1-Bromo-3-chloropropane's compatibility with multiple functional groups and its stability under various reaction conditions make it an excellent choice for organic synthesis strategies. Its reactivity towards nucleophiles and electrophiles enables chemists to access a diverse array of chemical products with tailored structures and functionalities. Whether employed in the development of novel pharmaceutical agents or the synthesis of advanced materials, 1-Bromo-3-chloropropane plays a crucial role in advancing the field of organic chemistry and driving innovation in chemical research.

Literature

• Two alanine aminotranferases link mitochondrial glycolate oxidation to the major photorespiratory pathway in Arabidopsis and rice.

  Journal of experimental botany 20120401

• Effects of female sex hormones on clusterin expression and paclitaxel resistance in endometrial cancer cell lines.

  International journal of medical sciences 20120101

• MG63 osteoblast-like cells exhibit different behavior when grown on electrospun collagen matrix versus electrospun gelatin matrix.

  PloS one 20120101

• Fenofibrate reduces mortality and precludes neurological deficits in survivors in murine model of Japanese encephalitis viral infection.

  PloS one 20120101

• Developmental exposure to bisphenol A modulates innate but not adaptive immune responses to influenza A virus infection.

  PloS one 20120101

• Coherent control of the ultrafast dissociative ionization dynamics of bromochloroalkanes.

  Physical chemistry chemical physics : PCCP 20110521

• Small interfering RNA mediated Poly (ADP-ribose) Polymerase-1 inhibition upregulates the heat shock response in a murine fibroblast cell line.

  Journal of inflammation (London, England) 20110101

• Activated protein synthesis and suppressed protein breakdown signaling in skeletal muscle of critically ill patients.

  PloS one 20110101

• 1,4-Bis(3-chloro-prop-oxy)benzene.

  Acta crystallographica. Section E, Structure reports online 20110101

• Age-related alterations in retinal neurovascular and inflammatory transcripts.

  Molecular vision 20110101

• The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans.

  PloS one 20110101

• IFN-α is constitutively expressed in the human thymus, but not in peripheral lymphoid organs.

  PloS one 20110101

• Deep sequencing the transcriptome reveals seasonal adaptive mechanisms in a hibernating mammal.

  PloS one 20110101

• Fatty acyl-CoA reductases of birds.

  BMC biochemistry 20110101

• Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stability.

  PloS one 20110101

• Conditional gene expression in Mycobacterium abscessus.

  PloS one 20110101

• [Synthesis and characterization of some new rutin and 7-aminocephalosporanic acid derivatives].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20110101

• Maternal and neonatal exposure to environmental tobacco smoke targets pro-inflammatory genes in neonatal arteries.

  Journal of cardiovascular translational research 20101201

• SREB, a GATA transcription factor that directs disparate fates in Blastomyces dermatitidis including morphogenesis and siderophore biosynthesis.

  PLoS pathogens 20100401

• Genetic adaptation of Streptococcus mutans during biofilm formation on different types of surfaces.

  BMC microbiology 20100101

• In vivo detection of extrapancreatic insulin gene expression in diabetic mice by bioluminescence imaging.

  PloS one 20100101

• Differential gene expression in human granulosa cells from recombinant FSH versus human menopausal gonadotropin ovarian stimulation protocols.

  Reproductive biology and endocrinology : RB&E 20100101

• Estrogen regulates estrogen receptors and antioxidant gene expression in mouse skeletal muscle.

  PloS one 20100101

• Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcripts.

  PloS one 20100101

• Sex-specific odorant receptors of the tobacco hornworm manduca sexta.

  Frontiers in cellular neuroscience 20100101

• Doxorubicin in vivo rapidly alters expression and translation of myocardial electron transport chain genes, leads to ATP loss and caspase 3 activation.

  PloS one 20100101

• Vascular cellular adhesion molecule-1 (VCAM-1) expression in mice retinal vessels is affected by both hyperglycemia and hyperlipidemia.

  PloS one 20100101

• Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.

  PloS one 20100101

• Redesigning dehalogenase access tunnels as a strategy for degrading an anthropogenic substrate.

  Nature chemical biology 20091001

• Complete chloroplast genome sequence of a major allogamous forage species, perennial ryegrass (Lolium perenne L.).

  DNA research : an international journal for rapid publication of reports on genes and genomes 20090601

• Ethanol impairs estrogen receptor signaling resulting in accelerated activation of senescence pathways, whereas estradiol attenuates the effects of ethanol in osteoblasts.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090201

• Methyl 4-(3-chloro-prop-oxy)-3-methoxy-benzoate.

  Acta crystallographica. Section E, Structure reports online 20090201

• Lef1 haploinsufficient mice display a low turnover and low bone mass phenotype in a gender- and age-specific manner.

  PloS one 20090101

• MicroRNA Expression Profiling by Bead Array Technology in Human Tumor Cell Lines Treated with Interferon-Alpha-2a.

  Biological procedures online 20090101

• Inheritance of acquired behaviour adaptations and brain gene expression in chickens.

  PloS one 20090101

• Progressive obesity leads to altered ovarian gene expression in the Lethal Yellow mouse: a microarray study.

  Journal of ovarian research 20090101

• Analysis of current and alternative phenol based RNA extraction methodologies for cyanobacteria.

  BMC molecular biology 20090101

• Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation.

  Arthritis research & therapy 20090101

• Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects.

  PloS one 20090101

• Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3.

  PloS one 20090101

• A reverse transcriptase-PCR assay for detecting filarial infective larvae in mosquitoes.

  PLoS neglected tropical diseases 20080601

• Substitutional disorder in the substituted nixantphos ligand C(39)H(32)Br(0.27)Cl(0.73)NOP(2).

  Acta crystallographica. Section E, Structure reports online 20080501

• Arsenic-induced changes in the gene expression of lung epithelial L2 cells: implications in carcinogenesis.

  BMC genomics 20080101

• Pioglitazone administration alters ovarian gene expression in aging obese lethal yellow mice.

  Reproductive biology and endocrinology : RB&E 20080101

• [Research concerning rutin semisynthetic derivatives. Synthesis, physico-chemical and microbiological characterisation of some new rutin-isoniazid derivatives].

  Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

• Cyclic changes in gene expression induced by Peg-interferon alfa-2b plus ribavirin in peripheral blood monocytes (PBMC) of hepatitis C patients during the first 10 weeks of treatment.

  Journal of translational medicine 20080101

• Genotoxicants target distinct molecular networks in neonatal neurons.

  Environmental health perspectives 20061101

• Synthesis and chemical characterization of 2-methoxy-N(10)-substituted acridones needed to reverse vinblastine resistance in multidrug resistant (MDR) cancer cells.

  Bioorganic & medicinal chemistry 20020701

• Digital analysis of cDNA abundance; expression profiling by means of restriction fragment fingerprinting.

  BMC genomics 20020101

• One-step synthesis and redox properties of dodecahydro-3a,9a-diazaperylene--the most easily oxidized p-phenylenediamine.

  Chemical communications (Cambridge, England) 20010921

• Synthesis of 1-(3-aminopropyl)-4-phenyl-1,2,4-triazolin-5-one and 1-(3-aminopropyl)-3,4-diphenyl-1,2,4-triazolin-5-one.

  Acta poloniae pharmaceutica 20010101