109-83-1 | 2-(Methylamino)ethanol

Packsize	Purity	Availability	Price	Discounted Price
25g	99%	in stock	$8.00	$5.00
100g	99%	in stock	$9.00	$6.00
500g	99%	in stock	$22.00	$15.00

Description

• Catalog Number: AB43500
• Chemical Name: 2-(Methylamino)ethanol
• CAS Number: 109-83-1
• Molecular Formula: C3H9NO
• Molecular Weight: 75.1097
• MDL Number: MFCD00002839
• SMILES: CNCCO
• NSC Number: 62776

Computed Properties

• Complexity: 16.4
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 5
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 2
• XLogP3: -0.9

Upstream Synthesis Route

2-(Methylamino)ethanol, also known as N-methylethanolamine, is a versatile compound commonly used in chemical synthesis. This compound serves as an important building block in the production of various pharmaceuticals, agrochemicals, and specialty chemicals. 2-(Methylamino)ethanol is used as a key intermediate in the synthesis of pharmaceuticals such as antihistamines, analgesics, and anti-infective agents. In agrochemical applications, this compound is utilized in the creation of pesticides and herbicides. Additionally, 2-(Methylamino)ethanol plays a crucial role in the synthesis of surfactants, dyes, and other specialty chemicals. Its ability to undergo various reactions and form diverse chemical bonds makes it a valuable tool in organic synthesis processes.

Literature

• Iridium-catalyzed oxidative methyl esterification of primary alcohols and diols with methanol.

  The Journal of organic chemistry 20110415

• 3-D-QSAR and docking studies on the neuronal choline transporter.

  Bioorganic & medicinal chemistry letters 20100815

• Progesterone modulation of transmembrane helix-helix interactions between the alpha-subunit of Na/K-ATPase and phospholipid N-methyltransferase in the oocyte plasma membrane.

  BMC structural biology 20100101

• New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine.

  Journal of medicinal chemistry 20090312

• Recovery of choline oxidase activity by in vitro recombination of individual segments.

  Applied microbiology and biotechnology 20081101

• Photostable, amino reactive and water-soluble fluorescent labels based on sulfonated rhodamine with a rigidized xanthene fragment.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• 4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration.

  Bioorganic & medicinal chemistry letters 20070301

• Hybrid materials covalently incorporated with isophorone-based dyes through sol-gel process for nonlinear optical applications.

  The journal of physical chemistry. B 20061005

• Enzymatic chemoselective synthesis of secondary-amide surfactant from N-methylethanol amine.

  Journal of bioscience and bioengineering 20051201

• Transient silylation of the guanosine O6 and amino groups facilitates N-acylation.

  Organic letters 20040722

• N-methylethanolamine attenuates cardiac fibrosis and improves diastolic function: inhibition of phospholipase D as a possible mechanism.

  European heart journal 20040701

• Molecular modeling studies on the active binding site of the blood-brain barrier choline transporter.

  Bioorganic & medicinal chemistry letters 20040621

• Preliminary evaluation of anticonvulsant activity of some 4-(benzyloxy)-benzamides.

  Acta poloniae pharmaceutica 20030101

• Role for phospholipid interactions in the trafficking defect of Delta F508-CFTR.

  Biochemistry 20020917

• Novel reactions of phosphorus(III) azides and isocyanates: unusual modes of cycloaddition with dipolarophiles and an unexpected case of ring expansion.

  Chemical communications (Cambridge, England) 20020107

• Comparative inhalation teratogenicity of four glycol ether solvents and an amino derivative in rats.

  Environmental health perspectives 19840801