109-99-9 | Tetrahydrofuran

Packsize	Purity	Availability	Price	Discounted Price
10ml	99%	in stock	$12.00	$8.00
25ml	99%	in stock	$15.00	$10.00
100ml	99%	in stock	$19.00	$13.00
250ml	99%	in stock	$23.00	$16.00
500ml	99%	in stock	$29.00	$20.00

Description

• Catalog Number: AB47119
• Chemical Name: Tetrahydrofuran
• CAS Number: 109-99-9
• Molecular Formula: C4H8O
• Molecular Weight: 72.10572
• MDL Number: MFCD00005356
• SMILES: C1CCCO1

Upstream Synthesis Route

Tetrahydrofuran (THF) is a versatile solvent commonly used in chemical synthesis due to its unique properties. As a cyclic ether, THF has a relatively low boiling point and good solubility for a wide range of compounds, making it an excellent choice for various reactions and processes in the laboratory and industry.In organic synthesis, THF serves as a polar aprotic solvent that can dissolve both polar and nonpolar compounds, facilitating reactions between different types of molecules. It is particularly useful in Grignard reactions, where it stabilizes the highly reactive magnesium alkoxide intermediates. THF also plays a crucial role in metal-catalyzed reactions and organometallic chemistry, enabling the formation of complex metal-carbon bonds.Additionally, THF is commonly employed in polymer chemistry for the synthesis of polytetramethylene ether glycol (PTMEG) and for the preparation of polyurethane foams. Its ability to solvate a wide range of polymers and its compatibility with various catalyst systems make it an essential solvent in polymerization processes.Moreover, THF is utilized in the pharmaceutical industry for the manufacturing of active pharmaceutical ingredients (APIs) and in drug formulation. Its solvating properties and low toxicity make it a preferred choice for drug synthesis and formulation processes.Overall, Tetrahydrofuran plays a crucial role in chemical synthesis as a versatile solvent that enables diverse reactions in organic, polymer, and pharmaceutical chemistry. Its unique properties make it an indispensable solvent in various chemical processes and industries.