1092352-40-3 | 4-Bromo-3,5-difluoropyridine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$79.00	$55.00
1g	95%	in stock	$167.00	$117.00
5g	95%	in stock	$742.00	$519.00
25g	95%	in stock	$3,089.00	$2,162.00

Description

• Catalog Number: AD64495
• Chemical Name: 4-Bromo-3,5-difluoropyridine
• CAS Number: 1092352-40-3
• Molecular Formula: C5H2BrF2N
• Molecular Weight: 193.9769
• MDL Number: MFCD11505879
• SMILES: Fc1cncc(c1Br)F

Computed Properties

• Complexity: 91
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• XLogP3: 1.7

Upstream Synthesis Route

4-Bromo-3,5-difluoropyridine is a versatile building block in chemical synthesis due to its unique structural properties and reactivity. This compound is commonly used in the pharmaceutical industry, agrochemical industry, and material science for the synthesis of various organic compounds and heterocycles.In chemical synthesis, 4-Bromo-3,5-difluoropyridine can serve as a key intermediate in the preparation of pharmaceuticals such as anti-cancer agents, antiviral drugs, and antibiotics. Its fluorine atoms and bromine substituents make it a valuable precursor for introducing fluorine atoms in drug molecules, which can enhance their biological activity and metabolic stability. Additionally, the pyridine ring system in 4-Bromo-3,5-difluoropyridine can participate in various coupling reactions, such as nucleophilic aromatic substitution and transition metal-catalyzed cross-coupling reactions, to construct complex molecular structures efficiently.Furthermore, 4-Bromo-3,5-difluoropyridine can be utilized in the synthesis of agrochemicals by functionalizing the pyridine ring with different substituents to modulate the biological activity of the resulting compounds. Its halogen atoms can also act as directing groups in organometallic reactions, enabling selective functionalization at specific positions on the pyridine ring.In material science, 4-Bromo-3,5-difluoropyridine can be employed for the synthesis of organic semiconductors, catalysts, and functional materials through various chemical transformations and polymerization processes. Its unique fluorinated and brominated functionalities can impart desirable properties such as electron-donating or electron-withdrawing effects, thermal stability, and solubility in organic solvents, making it a valuable building block for designing advanced materials with tailored properties.Overall, the application of 4-Bromo-3,5-difluoropyridine in chemical synthesis offers a wide range of possibilities for creating novel organic molecules with diverse applications in the fields of pharmaceuticals, agrochemicals, and materials science.