109299-78-7 | Pyrimidine-5-boronic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$13.00	$9.00
5g	98%	in stock	$24.00	$17.00
10g	98%	in stock	$44.00	$31.00
25g	98%	in stock	$93.00	$65.00

Description

• Catalog Number: AB45353
• Chemical Name: Pyrimidine-5-boronic acid
• CAS Number: 109299-78-7
• Molecular Formula: C4H5BN2O2
• Molecular Weight: 123.9057
• MDL Number: MFCD03002366
• SMILES: OB(c1cncnc1)O

Computed Properties

• Complexity: 84.6
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1

Upstream Synthesis Route

Pyrimidine-5-boronic acid is a versatile molecule that finds wide applications in chemical synthesis. As a boronic acid derivative, it serves as a valuable building block in the preparation of various organic compounds. One of its key applications is in the field of Suzuki-Miyaura cross-coupling reactions, where it can participate as a boron source to form C-C bonds. This enables the efficient construction of complex molecular structures, making it a crucial component in the synthesis of pharmaceuticals, agrochemicals, and materials science. Additionally, Pyrimidine-5-boronic acid can be employed in the functionalization of aromatic systems, offering a convenient route to introducing boron-containing functionalities into organic molecules. Its ability to undergo diverse chemical transformations highlights its importance as a key reagent in modern synthetic chemistry.

Literature

• 5-Pyrimidylboronic acid and 2-methoxy-5-pyrimidylboronic acid: new heteroarylpyrimidine derivatives via Suzuki cross-coupling reactions.

  Organic & biomolecular chemistry 20040321