1093-96-5 | N-[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]-N-methylglycine

Packsize	Purity	Availability	Price	Discounted Price
50mg	98%	2 weeks	$146.00	$103.00

Description

• Catalog Number: AB53719
• Chemical Name: N-[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]-N-methylglycine
• CAS Number: 1093-96-5
• Molecular Formula: C15H18N2O4S
• Molecular Weight: 322.3794
• MDL Number: MFCD00069542
• SMILES: OC(=O)CN(S(=O)(=O)c1cccc2c1cccc2N(C)C)C

Computed Properties

• Complexity: 500
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 2.2

Literature

• Effect of oxidative stress and endotoxin on human serum albumin in brain-dead organ donors.

  Translational research : the journal of laboratory and clinical medicine 20120601

• Pollutant-induced modulation in conformation and β-lactamase activity of human serum albumin.

  PloS one 20120101

• Effects of nonenzymatic glycation and fatty acids on functional properties of human albumin.

  Metabolism: clinical and experimental 20111201

• Binding of citrus flavanones and their glucuronides and chalcones to human serum albumin.

  Food & function 20111001

• Enantioselective binding of a lanthanide(III) complex to human serum albumin studied by 1H STD NMR techniques.

  Organic & biomolecular chemistry 20110721

• Structural basis of binding of fluorescent, site-specific dansylated amino acids to human serum albumin.

  Journal of structural biology 20110401

• A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.

  Bioorganic & medicinal chemistry 20101101

• Modeling kinetics of subcellular disposition of chemicals.

  Chemical reviews 20090513

• Olive phenols efficiently inhibit the oxidation of serum albumin-bound linoleic acid and butyrylcholine esterase.

  Biochimica et biophysica acta 20090401

• A fluorescence study of human serum albumin binding sites modification by hypochlorite.

  Journal of photochemistry and photobiology. B, Biology 20090209

• Improvement of impaired albumin binding capacity in acute-on-chronic liver failure by albumin dialysis.

  Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080901

• Structural and ligand-binding properties of serum albumin species interacting with a biomembrane interface.

  Journal of pharmaceutical sciences 20071101

• Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor.

  Bioorganic & medicinal chemistry letters 20070815

• Albumin-binding PARACEST agents.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070801

• Determination of drug-serum protein interactions via fluorescence polarization measurements.

  Analytical and bioanalytical chemistry 20070701

• Albumin-binding function is reduced in patients with decompensated cirrhosis and correlates inversely with severity of liver disease assessed by model for end-stage liver disease.

  European journal of gastroenterology & hepatology 20070301

• Synthesis and physicochemical characterization of two gadolinium(III) TTDA-like complexes and their interaction with human serum albumin.

  Inorganic chemistry 20060109

• Interaction of non-steroidal anti-inflammatory drugs, etoricoxib and parecoxib sodium, with human serum albumin studied by fluorescence spectroscopy.

  Drug metabolism and drug interactions 20060101

• High-throughput solution-based medicinal library screening against human serum albumin.

  Analytical chemistry 20050301

• Inhibitory effects of amino-acid fluids on drug binding to site II of human serum albumin in vitro.

  Biological & pharmaceutical bulletin 20050301

• The interaction of human serum albumin with a novel antidiabetic agent--SU-118.

  Journal of pharmaceutical sciences 20040401

• The effect of glycation on the structure, function and biological fate of human serum albumin as revealed by recombinant mutants.

  Biochimica et biophysica acta 20031013

• The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates.

  Journal of the American Chemical Society 20020327

• The Gd(3+) complex of a fatty acid analogue of DOTP binds to multiple albumin sites with variable water relaxivities.

  Inorganic chemistry 20011217

• In vitro and in vivo properties of recombinant human serum albumin from Pichia pastoris purified by a method of short processing time.

  Pharmaceutical research 20011201

• Flunitrazepam, a 7-nitro-1,4-benzodiazepine that is unable to bind to the indole-benzodiazepine site of human serum albumin.

  Biochimica et biophysica acta 20010407

• Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species.

  The Journal of pharmacy and pharmacology 20010401

• Interaction mechanism between indoxyl sulfate, a typical uremic toxin bound to site II, and ligands bound to site I of human serum albumin.

  Pharmaceutical research 20010401