1093100-40-3 | B-Raf inhibitor 1

Packsize	Purity	Availability	Price	Discounted Price
5mg		in stock	$224.00	$157.00
10mg		in stock	$316.00	$222.00
50mg		in stock	$816.00	$571.00
100mg		in stock	$1,185.00	$830.00

Description

• Catalog Number: AE11159
• Chemical Name: B-Raf inhibitor 1
• CAS Number: 1093100-40-3
• Molecular Formula: C26H19ClN8
• Molecular Weight: 478.9357
• MDL Number: MFCD22571725
• SMILES: Clc1ccc(cc1)Nc1nccc2c1ccc(c2Nc1ncccc1c1ncnc2c1[nH]cn2)C

Computed Properties

• Complexity: 690
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 35
• Hydrogen Bond Acceptor Count: 7
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: 5.6

Literature

• Conformation-specific effects of Raf kinase inhibitors.

  Journal of medicinal chemistry 20120913

• Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.

  Journal of medicinal chemistry 20091022