1095-85-8 | 2-(Tritylthio)ethanamine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$11.00	$8.00
1g	95%	in stock	$39.00	$27.00
5g	95%	in stock	$53.00	$38.00
10g	95%	in stock	$100.00	$70.00

Description

• Catalog Number: AI07880
• Chemical Name: 2-(Tritylthio)ethanamine
• CAS Number: 1095-85-8
• Molecular Formula: C21H21NS
• Molecular Weight: 319.46314
• MDL Number: MFCD00822629
• SMILES: NCCSC(c1ccccc1)(c1ccccc1)c1ccccc1
• NSC Number: 96704

Computed Properties

• Complexity: 279
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 6
• XLogP3: 4.6

Upstream Synthesis Route

2-(Tritylthio)ethanamine is a versatile compound that finds its application in various chemical synthesis processes. With its unique structure and reactivity, this compound serves as a valuable building block in organic chemistry. It is commonly used as a nucleophile in SN2 reactions, where it can participate in the formation of new carbon-carbon or carbon-heteroatom bonds. Additionally, 2-(Tritylthio)ethanamine can act as a protecting group for sensitive functional groups in organic synthesis, allowing selective manipulation of specific parts of a molecule. Its compatibility with a wide range of reaction conditions makes it a valuable tool for chemists working in the field of organic synthesis.

Literature

• Doing the methylene shuffle--further insights into the inhibition of mitotic kinesin Eg5 with S-trityl L-cysteine.

  European journal of medicinal chemistry 20120801

• Triphenylbutanamines: kinesin spindle protein inhibitors with in vivo antitumor activity.

  Journal of medicinal chemistry 20120223

• FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors.

  Anemia 20120101

• Synthesis and characterization of tritylthioethanamine derivatives with potent KSP inhibitory activity.

  Bioorganic & medicinal chemistry 20110915

• Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5.

  Journal of medicinal chemistry 20110324

• Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.

  Journal of medicinal chemistry 20080313