1095382-05-0 | CCT137690

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$48.00	$33.00
5mg	98%	in stock	$102.00	$71.00
10mg	98%	in stock	$130.00	$91.00
50mg	98%	in stock	$408.00	$285.00
100mg	98%	in stock	$633.00	$443.00

Description

• Catalog Number: AE11171
• Chemical Name: CCT137690
• CAS Number: 1095382-05-0
• Molecular Formula: C26H31BrN8O
• Molecular Weight: 551.4813
• MDL Number: MFCD18206879
• SMILES: CN1CCN(CC1)c1ccc(cc1)c1nc2c([nH]1)c(N1CCN(CC1)Cc1noc(c1)C)c(cn2)Br

Upstream Synthesis Route

CCT137690 is a potent and selective inhibitor of Aurora kinases, a family of serine/threonine kinases that play crucial roles in the regulation of cell division. In chemical synthesis, CCT137690 is commonly used to target and inhibit Aurora kinases, thereby preventing the phosphorylation of substrates involved in mitosis. By interfering with the activity of Aurora kinases, CCT137690 effectively disrupts cell cycle progression and promotes cell death, making it a valuable tool in investigating the mechanisms of cell division and potential therapeutic interventions targeting cancer cells. Furthermore, CCT137690's specificity towards Aurora kinases makes it a valuable reagent for studying the functions and pathways associated with these key regulators of mitosis.