1096708-71-2 | 4-Pyrimidinecarboxamide, 6-amino-5-chloro-n-[(1r)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]-2-thiazolyl]ethyl]-

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$58.00	$41.00
5mg	98%	in stock	$222.00	$155.00
10mg	98%	in stock	$290.00	$203.00
50mg	98%	in stock	$1,315.00	$920.00

Description

• Catalog Number: AE11290
• Chemical Name: 4-Pyrimidinecarboxamide, 6-amino-5-chloro-n-[(1r)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]-2-thiazolyl]ethyl]-
• CAS Number: 1096708-71-2
• Molecular Formula: C17H12Cl2F3N7O2S
• Molecular Weight: 506.2891
• MDL Number: MFCD22571730
• SMILES: CC(c1ncc(s1)C(=O)Nc1ncc(c(c1)C(F)(F)F)Cl)NC(=O)c1ncnc(c1Cl)N

Computed Properties

• Complexity: 695
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 32
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 5
• XLogP3: 3

Upstream Synthesis Route

6-Amino-5-chloro-N-[(1R)-1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]-2-thiazolyl]ethyl]-4-pyrimidinecarboxamide is a versatile compound commonly used in chemical synthesis for the development of pharmaceuticals, agrochemicals, and other fine chemicals. This compound has shown great potential as a building block in the synthesis of various biologically active molecules due to its unique structure and functional groups. In chemical synthesis, it serves as a key intermediate for the formation of complex molecular structures through selective reactions and modifications. This compound's strategic placement of functional groups enables precise manipulation and transformation into diverse derivatives with enhanced properties and activities, making it a valuable tool for synthetic chemists in the production of novel compounds with potential applications in various industries.

Literature

• A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas.

  Neuro-oncology 20170601