1098-97-1 | Pyrithioxin

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$11.00	$8.00
25mg	98%	in stock	$14.00	$10.00
100mg	98%	in stock	$17.00	$12.00
250mg	98%	in stock	$21.00	$15.00
1g	98%	in stock	$25.00	$18.00
5g	98%	in stock	$50.00	$35.00
25g	98%	in stock	$171.00	$120.00
100g	98%	in stock	$573.00	$402.00

Description

• Catalog Number: AI07985
• Chemical Name: Pyrithioxin
• CAS Number: 1098-97-1
• Molecular Formula: C16H20N2O4S2
• Molecular Weight: 368.471
• MDL Number: MFCD00151477
• SMILES: OCc1c(CSSCc2cnc(c(c2CO)O)C)cnc(c1O)C
• NSC Number: 759229

Computed Properties

• Complexity: 346
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 7
• XLogP3: 1.2

Upstream Synthesis Route

Pyrithioxin, also known as 1,4-dihydroxy-2,5-diethylthio benzene, is a versatile compound widely used in chemical synthesis. Its unique structure and properties make it a valuable tool in various reactions and processes in the field of chemistry.In chemical synthesis, Pyrithioxin serves as an essential building block for creating diverse organic compounds. Its thioether functional group enables it to participate in thiol-based reactions, such as thiol-ene and thiol-Michael additions, leading to the formation of new carbon-sulfur bonds. This characteristic makes Pyrithioxin a valuable reagent for constructing complex molecular structures in organic synthesis.Additionally, Pyrithioxin's dihydroxy benzene moiety can undergo various functionalization reactions, such as electrophilic aromatic substitutions and oxidative coupling reactions. These transformations enable the incorporation of Pyrithioxin into larger molecular frameworks, allowing for the synthesis of novel compounds with tailored properties and functionalities.Furthermore, Pyrithioxin's ability to undergo redox reactions makes it a versatile reagent for catalyzing oxidation-reduction processes in chemical synthesis. Its redox-active nature allows for the transfer of electrons during reactions, facilitating the conversion of substrates into desired products with high efficiency and selectivity.Overall, Pyrithioxin plays a crucial role in chemical synthesis by serving as a key building block, catalyst, and reagent for creating a wide range of organic compounds with diverse structures and functionalities. Its unique properties make it a valuable tool for researchers and chemists working in various fields, including medicinal chemistry, materials science, and drug discovery.

Literature

• Selective Vulnerabilities of N-methyl-D-aspartate (NMDA) Receptors During Brain Aging.

  Frontiers in aging neuroscience 20100101

• Stability-indicating chemometric methods for the determination of pyritinol dihydrochloride.

  Drug testing and analysis 20090501

• Pyritinol for post asphyxial encephalopathy in term babies-- a randomized double-blind controlled trial.

  Indian pediatrics 20090101

• Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

  Journal of medicinal chemistry 20081113

• Pyritinol reduces nociception and oxidative stress in diabetic rats.

  European journal of pharmacology 20080820

• Stability-indicating electrochemical methods for the determination of meclophenoxate hydrochloride and pyritinol dihydrochloride using ion-selective membrane electrodes.

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070101

• Stability-indicating methods for determination of pyritinol dihydrochloride in the presence of its precursor and degradation product by derivative spectrophotometry.

  Journal of AOAC International 20050101

• Prolongevity medicine: Antagonic-Stress drug in distress, geriatrics, and related diseases. II. Clinical review--2003.

  Annals of the New York Academy of Sciences 20040601

• Severe cholestatic hepatitis induced by pyritinol.

  BMJ (Clinical research ed.) 20040306

• [Current strategies of pathogenetic therapy of Alzheimer's disease].

  Vestnik Rossiiskoi akademii meditsinskikh nauk 20010101

• Effect of nicergoline on learning and memory.

  Methods and findings in experimental and clinical pharmacology 19880701