110-85-0 | Piperazine

Packsize	Purity	Availability	Price	Discounted Price
5g	99%	in stock	$13.00	$9.00
25g	99%	in stock	$19.00	$13.00
100g	99%	in stock	$22.00	$15.00
250g	99%	in stock	$32.00	$22.00
500g	99%	in stock	$58.00	$40.00

Description

• Catalog Number: AB78378
• Chemical Name: Piperazine
• CAS Number: 110-85-0
• Molecular Formula: C4H10N2
• Molecular Weight: 86.1356
• MDL Number: MFCD00005953
• SMILES: N1CCNCC1

Computed Properties

• Complexity: 26.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: -1.5

Upstream Synthesis Route

Piperazine, a versatile chemical compound, plays a crucial role in various chemical synthesis processes. It is widely used as a building block in the creation of pharmaceuticals, agrochemicals, and specialty chemicals due to its unique chemical properties. In chemical synthesis, piperazine serves as a key intermediate in the production of diverse compounds, offering opportunities for the modification of molecular structures and the development of new materials.Piperazine's ability to act as a bridging molecule enables it to facilitate the formation of complex organic molecules with specific functions. Its presence in the synthesis of pharmaceuticals is particularly notable, as it often serves as a core component in the production of drugs targeting various medical conditions. Additionally, piperazine's role in agrochemical synthesis contributes to the creation of pesticides and herbicides that are essential for crop protection and enhanced agricultural productivity.Furthermore, piperazine's reactivity and compatibility with a wide range of functional groups make it a valuable tool in the field of organic chemistry. Its incorporation into chemical reactions allows for the efficient construction of diverse molecular frameworks with tailored properties. By harnessing the versatility of piperazine in chemical synthesis, researchers and industrial chemists can explore innovative pathways for producing advanced materials and compounds with applications across multiple industries.

Literature

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  Dalton transactions (Cambridge, England : 2003) 20120221

• Ring-opening reactions of 1,4-diazabicyclo[2.2.2]octane (DABCO) derived quaternary ammonium salts with phenols and related nucleophiles.

  Organic & biomolecular chemistry 20120214

• Randomized trial using gonadotropin-releasing hormone agonist triptorelin for the preservation of ovarian function during (neo)adjuvant chemotherapy for breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210

• Synthesis and structure-activity relationship study of antimicrotubule agents phenylahistin derivatives with a didehydropiperazine-2,5-dione structure.

  Journal of medicinal chemistry 20120209

• Reverse engineering finger extensor apparatus morphology from measured coupled interphalangeal joint angle trajectories - a generic 2D kinematic model.

  Journal of biomechanics 20120202

• Evaluation of in vitro percutaneous absorption of olanzapine and fluoxetine HCl: enhancement properties of olanzapine.

  Drug development and industrial pharmacy 20120201

• Anatomy and function of lumbrical muscles.

  Hand clinics 20120201

• Spectroscopic evidence for an oxazolone structure in anionic b-type peptide fragments.

  Journal of the American Society for Mass Spectrometry 20120201

• Triggering with GnRH agonist in oocyte-donation cycles: oestradiol monitoring is not necessary during ovarian stimulation.

  Reproductive biomedicine online 20120201

• Native FKBP12 engineering by ligand-directed tosyl chemistry: labeling properties and application to photo-cross-linking of protein complexes in vitro and in living cells.

  Journal of the American Chemical Society 20120201

• μ-1,4-Bis(pyridin-4-ylmeth-yl)piperazine-κN:N'-bis-[aqua-bis-(3-bromo-5-carb-oxy-benzoato-κO)copper(II)].

  Acta crystallographica. Section E, Structure reports online 20120201

• 2-Amino-pyridinium bis-(pyridine-2,6-dicarboxyl-ato)ferrate(III).

  Acta crystallographica. Section E, Structure reports online 20120201

• Poly[piperazine-1,4-diium [μ(4)-chlorido-μ(3)-chlorido-tri-μ(2)-chlorido-chloridodicadmate(II)] monohydrate].

  Acta crystallographica. Section E, Structure reports online 20120201

• (E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(3,4-dieth-oxy-phen-yl)prop-2-en-1-one ethanol disolvate.

  Acta crystallographica. Section E, Structure reports online 20120201

• 3-(Adamantan-1-yl)-1-[(4-benzyl-piperazin-1-yl)meth-yl]-4-phenyl-1H-1,2,4-triazole-5(4H)-thione.

  Acta crystallographica. Section E, Structure reports online 20120201

• 3-(Adamantan-1-yl)-4-phenyl-1-[(4-phenyl-piperazin-1-yl)meth-yl]-1H-1,2,4-triazole-5(4H)-thione.

  Acta crystallographica. Section E, Structure reports online 20120201

• Ethyl 4-{[3-(adamantan-1-yl)-4-phenyl-5-sulfanyl-idene-4,5-dihydro-1H-1,2,4-triazol-1-yl]meth-yl}piperazine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20120201

• DOGS: reaction-driven de novo design of bioactive compounds.

  PLoS computational biology 20120201

• Oligomerization of glycine and alanine catalyzed by iron oxides: implications for prebiotic chemistry.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20120201

• Gastroprotective activity and mechanism of novel dichlorido-zinc(II)-4-(2-(5-methoxybenzylideneamino)ethyl)piperazin-1-iumphenolate complex on ethanol-induced gastric ulceration.

  Chemico-biological interactions 20120125

• Solid-phase synthesis of NMe-IB-01212, a highly N-methylated cyclic peptide.

  Organic letters 20120120

• Degradation of polyamide nanofiltration and reverse osmosis membranes by hypochlorite.

  Environmental science & technology 20120117

• Heteroaromatic-aminomethyl quinolones: potent and selective iNOS inhibitors.

  Bioorganic & medicinal chemistry letters 20120115

• Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A₁ adenosine receptor.

  Bioorganic & medicinal chemistry 20120115

• Multiparameter exploration of piperazine derivatives as δ-opioid receptor agonists for CNS indications.

  Bioorganic & medicinal chemistry letters 20120115

• The discovery of potent antagonists of NPBWR1 (GPR7).

  Bioorganic & medicinal chemistry letters 20120115

• Synthesis of new praziquantel analogues: potential candidates for the treatment of schistosomiasis.

  Bioorganic & medicinal chemistry letters 20120115

• Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.

  Journal of medicinal chemistry 20120112

• Differential protection of neuromuscular sensory and motor axons and their endings in Wld(S) mutant mice.

  Neuroscience 20120103

• Reduced pelvic pain in women with endometriosis: efficacy of long-term dienogest treatment.

  Archives of gynecology and obstetrics 20120101

• Searching for novel anti-myotonic agents: pharmacophore requirement for use-dependent block of skeletal muscle sodium channels by N-benzylated cyclic derivatives of tocainide.

  Neuromuscular disorders : NMD 20120101

• Mass-spectrometric studies of new 6-nitroquipazines-serotonin transporter inhibitors.

  Analytical and bioanalytical chemistry 20120101

• Prevalence of efflux-mediated ciprofloxacin and levofloxacin resistance in recent clinical isolates of Pseudomonas aeruginosa and its reversal by the efflux pump inhibitors 1-(1-naphthylmethyl)-piperazine and phenylalanine-arginine-β-naphthylamide.

  International journal of antimicrobial agents 20120101

• Urinary metabolite markers of precocious puberty.

  Molecular & cellular proteomics : MCP 20120101

• Sunlight-induced degradation of soil-adsorbed veterinary antimicrobials Marbofloxacin and Enrofloxacin.

  Chemosphere 20120101

• Cyclosulfamide-based derivatives as inhibitors of noroviruses.

  European journal of medicinal chemistry 20120101

• Nitrogen dioxide oxidizes mitochondrial cytochrome c.

  Free radical biology & medicine 20120101

• Inhibition of noroviruses by piperazine derivatives.

  Bioorganic & medicinal chemistry letters 20120101

• New N-methylpiperazinyl derivatives of bicyclic antiprotozoal compounds.

  European journal of medicinal chemistry 20120101

• The comparative effectiveness of combined lumbrical muscle splints and stretches on symptoms and function in carpal tunnel syndrome.

  Archives of physical medicine and rehabilitation 20120101

• Crystallization and preliminary X-ray crystallographic studies of the outer membrane cytochrome OmcA from Shewanella oneidensis MR-1.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20120101

• Multiple approaches for individualized fertility protective therapy in cancer patients.

  Obstetrics and gynecology international 20120101

• cis-Bis(4-methyl-piperazine-1-carbo-dithio-ato-κS,S')bis-(pyridine-κN)cadmium.

  Acta crystallographica. Section E, Structure reports online 20120101

• (E)-1-{4-[Bis(4-bromo-phen-yl)meth-yl]piperazin-1-yl}-3-(4-eth-oxy-3-meth-oxy-phen-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20120101

• N-{2-[4-(2-Hy-droxy-eth-yl)piperazin-1-yl]eth-yl}phthalimide.

  Acta crystallographica. Section E, Structure reports online 20120101

• 2-Chloro-1-[4-(2,4-difluoro-benz-yl)piperazin-1-yl]ethanone.

  Acta crystallographica. Section E, Structure reports online 20120101

• 2-(5-Fluoro-2,3-dioxoindolin-1-yl)ethyl 4-methyl-piperazine-1-carbodithio-ate.

  Acta crystallographica. Section E, Structure reports online 20120101

• Transcriptional analysis of Shewanella oneidensis MR-1 with an electrode compared to Fe(III)citrate or oxygen as terminal electron acceptor.

  PloS one 20120101

• Plasmid-Mediated Quinolone Resistance; Interactions between Human, Animal, and Environmental Ecologies.

  Frontiers in microbiology 20120101

• Identification and Characterization of MtoA: A Decaheme c-Type Cytochrome of the Neutrophilic Fe(II)-Oxidizing Bacterium Sideroxydans lithotrophicus ES-1.

  Frontiers in microbiology 20120101

• Major clinical research advances in gynecologic cancer in 2011.

  Journal of gynecologic oncology 20120101

• Therapeutic application of natural inhibitors against snake venom phospholipase A(2).

  Bioinformation 20120101

• Molecular Underpinnings of Fe(III) Oxide Reduction by Shewanella Oneidensis MR-1.

  Frontiers in microbiology 20120101

• Reconstruction of Extracellular Respiratory Pathways for Iron(III) Reduction in Shewanella Oneidensis Strain MR-1.

  Frontiers in microbiology 20120101

• Acute oral toxicity evaluations of some zinc(II) complexes derived from 1-(2-salicylaldiminoethyl)piperazine Schiff bases in rats.

  International journal of molecular sciences 20120101

• Management of extensor tendon injuries.

  The open orthopaedics journal 20120101

• Redefining hormone sensitive disease in advanced prostate cancer.

  Advances in urology 20120101

• Comparison of cytokine profiles in bronchoalveolar lavage fluid of mice exposed to respiratory and contact sensitizers.

  The Journal of toxicological sciences 20120101

• Losing the battle but winning the war: game theoretic analysis of the competition between motoneurons innervating a skeletal muscle.

  Frontiers in computational neuroscience 20120101

• Structural insights from binding poses of CCR2 and CCR5 with clinically important antagonists: a combined in silico study.

  PloS one 20120101

• Molecular dynamics simulation study and hybrid pharmacophore model development in human LTA4H inhibitor design.

  PloS one 20120101

• Gender dimorphism in aspartame-induced impairment of spatial cognition and insulin sensitivity.

  PloS one 20120101

• Innovative oral treatments of uterine leiomyoma.

  Obstetrics and gynecology international 20120101

• Fertility-sparing surgery in early epithelial ovarian cancer: a viable option?

  Obstetrics and gynecology international 20120101

• Barbed screw through the hand.

  Eplasty 20120101

• A 43-year-old woman on triptorelin presenting with pseudotumor cerebri: a case report.

  Journal of medical case reports 20120101

• Antimycobacterial Activities of Novel 5-(1H-1,2,3-Triazolyl)Methyl Oxazolidinones.

  Tuberculosis research and treatment 20120101

• Microwave assisted synthesis and determination of in-vitro antimicrobial efficacy of well characterized s-triazinyl piperazines and piperidines.

  Acta poloniae pharmaceutica 20120101

• The pyrolytic profile of lyophilized and deep-frozen compact part of the human bone.

  TheScientificWorldJournal 20120101

• Reproductive late effects in female survivors of childhood cancer.

  Obstetrics and gynecology international 20120101

• Behavioral aggressiveness in boys with sexual precocity.

  Indian journal of endocrinology and metabolism 20120101

• Evaluation of GnRH analogue testing in diagnosis and management of children with pubertal disorders.

  Indian journal of endocrinology and metabolism 20120101

• Solid phase synthesis of a functionalized bis-peptide using 'safety catch' methodology.

  Journal of visualized experiments : JoVE 20120101

• Central precocious puberty: treatment with triptorelin 11.25 mg.

  TheScientificWorldJournal 20120101

• Cardiometabolic complications after androgen deprivation therapy in a man with prostate cancer: effects of 3 years intermittent testosterone supplementation.

  Frontiers in endocrinology 20120101

• Low-dose chemotherapy with insulin (insulin potentiation therapy) in combination with hormone therapy for treatment of castration-resistant prostate cancer.

  ISRN urology 20120101

• Performance of repetitive tasks induces decreased grip strength and increased fibrogenic proteins in skeletal muscle: role of force and inflammation.

  PloS one 20120101

• Synthesis, 5-hydroxytryptamine1A receptor affinity and docking studies of 3-[3-(4-aryl-1-piperazinyl)-propyl]-1H-indole derivatives.

  Chemical & pharmaceutical bulletin 20120101

• The anticholinesterase phenserine and its enantiomer posiphen as 5'untranslated-region-directed translation blockers of the Parkinson's alpha synuclein expression.

  Parkinson's disease 20120101

• On the Role of Cannabinoid CB1- and μ-Opioid Receptors in Motor Impulsivity.

  Frontiers in pharmacology 20120101

• Antimicrobial and biofilm inhibiting diketopiperazines.

  Current medicinal chemistry 20120101

• Oxytocin and vasopressin secretion from the rat hypothalamo-neurohypophysial system is stimulated by triptorelin.

  Endokrynologia Polska 20120101

• Paradoxical extension phenomenon of the little finger due to repetitive trauma to the palm.

  Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand 20120101

• Trimetazidine protects against smoking-induced left ventricular remodeling via attenuating oxidative stress, apoptosis, and inflammation.

  PloS one 20120101

• Clinical outcome of one-third-dose depot triptorelin is the same as half-dose depot triptorelin in the long protocol of controlled ovarian stimulation.

  Journal of human reproductive sciences 20120101

• Novel piperazinyl derivatives with anti-hyperalgesic, anti-allodynic and anti-inflammatory activities useful for the treatment of Neuropathic Pain.

  Anti-inflammatory & anti-allergy agents in medicinal chemistry 20120101

• The effects of cetrorelix and triptorelin on the viability and steroidogenesis of cultured human granulosa luteinized cells.

  In vivo (Athens, Greece) 20120101

• Changes in apparent molar water volume and DKP solubility yield insights on the Hofmeister effect.

  The journal of physical chemistry. B 20111215

• Identification of novel sildenafil-analogues in an adulterated herbal food supplement.

  Journal of pharmaceutical and biomedical analysis 20111205

• Biosynthesis and identification of an N-oxide/N-glucuronide metabolite and first synthesis of an N-O-glucuronide metabolite of Lu AA21004.

  Drug metabolism and disposition: the biological fate of chemicals 20111201

• The lumbrical muscle: a novel in situ system to evaluate adult skeletal muscle proteolysis and anticatabolic drugs for therapeutic purposes.

  Journal of applied physiology (Bethesda, Md. : 1985) 20111201

• Degradation of the antibiotics norfloxacin and ciprofloxacin by a white-rot fungus and identification of degradation products.

  Bioresource technology 20111201

• Pharmacophore-based discovery of FXR agonists. Part I: Model development and experimental validation.

  Bioorganic & medicinal chemistry 20111201

• Design, synthesis, and biological evaluation of a novel series of bisintercalating DNA-binding piperazine-linked bisanthrapyrazole compounds as anticancer agents.

  Bioorganic & medicinal chemistry 20111201

• Synthesis of macrolones with central piperazine ring in the linker and its influence on antibacterial activity.

  Bioorganic & medicinal chemistry 20111201

• [A bilateral and symmetric anatomic variation of a lombrical muscle causing a trigger finger].

  Chirurgie de la main 20111201

• Bis(piperazine-1,4-diium) hexa-chlorido-bismuthate(III) chloride monohydrate.

  Acta crystallographica. Section E, Structure reports online 20111201

• (E)-1-(4-Benzhydrylpiperazin-1-yl)-3-(2-eth-oxy-phen-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20111201

• Piperazine-1,4-diium diacetate.

  Acta crystallographica. Section E, Structure reports online 20111201

• 1-(2-Aza-niumyleth-yl)piperazine-1,4-diium trinitrate.

  Acta crystallographica. Section E, Structure reports online 20111201

• (E)-1-{4-[Bis(4-fluoro-phen-yl)meth-yl]piperazin-1-yl}-3-(4-eth-oxy-phen-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20111201

• (E)-1-{4-[Bis(4-bromo-phen-yl)meth-yl]piperazin-1-yl}-3-(4-bromo-phen-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20111201

• [3-Bromo-meth-yl-1-(4-methyl-phenyl-sulfon-yl)azetidin-3-yl]methanol.

  Acta crystallographica. Section E, Structure reports online 20111201

• Bis[(2R,6S)-4-(5-amino-3-carb-oxy-1-cyclo-propyl-6,8-difluoro-4-oxo-1,4-dihydro-quinolin-7-yl)-2,6-dimethyl-piperazin-1-ium] sulfate penta-hydrate.

  Acta crystallographica. Section E, Structure reports online 20111201

• (2R)-4-[(9H-Fluoren-9-ylmeth-oxy)carbon-yl]-2-methyl-piperazin-1-ium chloride.

  Acta crystallographica. Section E, Structure reports online 20111201

• 3-[4-(10H-Indolo[3,2-b]quinolin-11-yl)piperazin-1-yl]propan-1-ol.

  Acta crystallographica. Section E, Structure reports online 20111201

• The 5-HT(1A) agonism potential of substituted piperazine-ethyl-amide derivatives is conserved in the hexyl homologues: molecular modeling and pharmacological evaluation.

  Journal of chemical information and modeling 20111128

• Formulation and evaluation of an in situ gel forming system for controlled delivery of triptorelin acetate.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

• Anterior interosseous nerve syndrome: retrospective analysis of 14 patients.

  Archives of orthopaedic and trauma surgery 20111101

• Identification of a new sildenafil analogue in a health supplement.

  Journal of pharmaceutical and biomedical analysis 20111101

• First case of transformation for breast fibroadenoma to high-grade malignant cystosarcoma in an in vitro fertilization patient.

  Fertility and sterility 20111101

• Preservation of ovarian function and minimizing premature ovarian failure during chemotherapy using gonadotropin-releasing hormone analogs.

  Women's health (London, England) 20111101

• Powder X-ray study of racemic (2RS,3RS)-5-amino-3-[4-(3-methoxyphenyl)piperazin-1-yl]-1,2,3,4-tetrahydronaphthalen-2-ol.

  Acta crystallographica. Section C, Crystal structure communications 20111101

• (μ-Piperazine-1,4-dicarbodithio-ato-κS,S:S,S)bis-[bis-(triphenyl-phos-phane-κP)gold(I)] chloro-form disolvate.

  Acta crystallographica. Section E, Structure reports online 20111101

• N-[(R)-(6-Bromo-2-meth-oxy-quinolin-3-yl)(phen-yl)meth-yl]-N-[(S)-1-(4-meth-oxy-phen-yl)eth-yl]-2-(piperazin-1-yl)acetamide.

  Acta crystallographica. Section E, Structure reports online 20111101

• 10α-Hy-droxy-4,9-dimethyl-13-[(4-phenyl-piperazin-1-yl)meth-yl]-3,8,15-trioxatetra-cyclo-[10.3.0.0.0]tetra-decan-14-one.

  Acta crystallographica. Section E, Structure reports online 20111101

• 2-{[2-(Piperazin-4-ium-1-yl)ethyl-iminio]meth-yl}phenolate 0.06-chloride 0.94-perchlorate.

  Acta crystallographica. Section E, Structure reports online 20111101

• (E)-1-(4-Benzhydrylpiperazin-1-yl)-3-(3,4-dieth-oxy-phen-yl)prop-2-en-1-one ethanol monosolvate.

  Acta crystallographica. Section E, Structure reports online 20111101

• Opipramol dihydro-chloride.

  Acta crystallographica. Section E, Structure reports online 20111101

• 1,4-Bis(4-tert-but-ylbenz-yl)piperazine.

  Acta crystallographica. Section E, Structure reports online 20111101

• 4-(o-Tol-yl)piperazin-1-ium chloride.

  Acta crystallographica. Section E, Structure reports online 20111101

• 4-(4-Methyl-piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro-meth-yl)quinoline.

  Acta crystallographica. Section E, Structure reports online 20111101

• Glionitrin B, a cancer invasion inhibitory diketopiperazine produced by microbial coculture.

  Journal of natural products 20111028

• Α-pyrones and diketopiperazine derivatives from the marine-derived actinomycete Nocardiopsis dassonvillei HR10-5.

  Journal of natural products 20111028

• Combined 3D-QSAR, molecular docking, and molecular dynamics study on piperazinyl-glutamate-pyridines/pyrimidines as potent P2Y12 antagonists for inhibition of platelet aggregation.

  Journal of chemical information and modeling 20111024

• OFF-ON-OFF fluorescence switch with T-latch function.

  Organic letters 20111021

• Preparation, spectral and biological investigation of formaldehyde-based ligand containing piperazine moiety and its various polymer metal complexes.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015

• Expedient entry to the piperazinohydroisoquinoline ring system using a sequential Ugi/Pictet-Spengler/reductive methylation reaction protocol.

  Chemical communications (Cambridge, England) 20111014

• Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas.

  Journal of medicinal chemistry 20111013

• Pore with gate: enhancement of the isosteric heat of adsorption of dihydrogen via postsynthetic cation exchange in metal-organic frameworks.

  Inorganic chemistry 20111003

• NSC126188, a piperazine alkyl derivative, induces apoptosis via upregulation of RhoB in HeLa cells.

  Investigational new drugs 20111001

• The origin of the premotor potential recorded from the second lumbrical muscle in normal man.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20111001

• Reactivity of alanylalanine diastereoisomers in neutral and acid aqueous solutions: a versatile stereoselectivity.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20111001

• GnRH agonist ovulation trigger and hCG-based, progesterone-free luteal support: a proof of concept study.

  Human reproduction (Oxford, England) 20111001

• Effects of linker elongation in a series of N-(2-benzofuranylmethyl)-N'-(methoxyphenylalkyl)piperazine σ₁ receptor ligands.

  Bioorganic & medicinal chemistry letters 20111001

• Discovery of inhibitors of plasminogen activator inhibitor-1: structure-activity study of 5-nitro-2-phenoxybenzoic acid derivatives.

  Bioorganic & medicinal chemistry letters 20111001

• Powder X-ray study of racemic (2RS,3RS)-5-amino-3-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol.

  Acta crystallographica. Section C, Crystal structure communications 20111001

• Gonadotropin-releasing hormone stimulation test for precocious puberty.

  The Korean journal of laboratory medicine 20111001

• Ovarian hyper-response to administration of an GnRH-agonist without gonadotropins.

  Journal of Korean medical science 20111001

• Tris(2,2'-bi-1H-imidazole-κN,N)cobalt(II) hydrogen phosphate.

  Acta crystallographica. Section E, Structure reports online 20111001

• N-(4-Chloro-phen-yl)-4-ethyl-piperazine-1-carboxamide.

  Acta crystallographica. Section E, Structure reports online 20111001

• 1-Diphenyl-methyl-4-[3-(4-fluoro-benzo-yl)prop-yl]piperazine-1,4-diium dichloride monohydrate.

  Acta crystallographica. Section E, Structure reports online 20111001

• 4-[Bis(4-fluorophenyl)methyl]piperazin-1-ium picrate.

  Acta crystallographica. Section E, Structure reports online 20111001

• (E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(4-methyl-phen-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20111001

• 4-[Bis(4-fluorophenyl)methyl]piperazin-1-ium 2-(2-phenylethyl)benzoate.

  Acta crystallographica. Section E, Structure reports online 20111001

• Piperazine-1,4-diium naphthalene-1,5-disulfonate.

  Acta crystallographica. Section E, Structure reports online 20111001

• [Clinical values of single or repeated triptorelin stimulating test in the differential diagnosis between idiopathic hypogonadotropic hypogonadism and constitutional delayed puberty].

  Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20111001

• Design, synthesis, anticonvulsant screening and 5HT_1A/2A receptor affinity of N(3)-substituted 2,4-imidazolidinediones and oxazolidinediones.

  Drug discoveries & therapeutics 20111001

• Solution-based structural analysis of the decaheme cytochrome, MtrA, by small-angle X-ray scattering and analytical ultracentrifugation.

  The journal of physical chemistry. B 20110929

• A 3D chiral porous In(III) coordination polymer with PtS topological net.

  Dalton transactions (Cambridge, England : 2003) 20110928

• Concise total synthesis and stereochemical revision of (+)-naseseazines A and B: regioselective arylative dimerization of diketopiperazine alkaloids.

  Journal of the American Chemical Society 20110928

• Reproductive endocrinology: triptorelin ovarian suppression during breast cancer chemotherapy.

  Nature reviews. Endocrinology 20110920

• Gas-phase nucleophilic aromatic substitution between piperazine and halobenzyl cations: reactivity of the methylene arenium form of benzyl cations.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20110919

• Fragment library screening reveals remarkable similarities between the G protein-coupled receptor histamine H₄ and the ion channel serotonin 5-HT₃A.

  Bioorganic & medicinal chemistry letters 20110915

• Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates.

  Bioorganic & medicinal chemistry letters 20110915

• Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection.

  Nature 20110915

• Expeditious one-pot synthesis of C3-piperazinyl-substituted quinolines: key precursors to potent c-Met inhibitors.

  Organic & biomolecular chemistry 20110907

• A near-infrared fluorescence turn-on sensor for sulfide anions.

  Organic letters 20110902

• Subjective effects in humans following administration of party pill drugs BZP and TFMPP alone and in combination.

  Drug testing and analysis 20110901

• Evaluation of two doses of recombinant human luteinizing hormone supplementation in down-regulated women of advanced reproductive age undergoing follicular stimulation for IVF: a randomized clinical study.

  European journal of obstetrics, gynecology, and reproductive biology 20110901

• Photodegradation of fleroxacin injection: different products with different concentration levels.

  AAPS PharmSciTech 20110901

• Synthesis and anticonvulsant properties of new acetamide derivatives of phthalimide, and its saturated cyclohexane and norbornene analogs.

  European journal of medicinal chemistry 20110901

• N-centered odd-electron ions formation from collision-induced dissociation of electrospray ionization generated even-electron ions: single electron transfer via ion/neutral complex in the fragmentation of protonated N,N'-dibenzylpiperazines and protonated N-benzylpiperazines.

  Journal of the American Society for Mass Spectrometry 20110901

• Contemporary issues in precocious puberty.

  Indian journal of endocrinology and metabolism 20110901

• Ethyl 4-(phenyl-sulfon-yl)piperazine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20110901

• N-(4-Chloro-phen-yl)-4-methyl-piperazine-1-carboxamide.

  Acta crystallographica. Section E, Structure reports online 20110901

• 4-(2-Azaniumyl-eth-yl)piperazin-1-ium bis(perchlorate).

  Acta crystallographica. Section E, Structure reports online 20110901

• Opipramolium fumarate.

  Acta crystallographica. Section E, Structure reports online 20110901

• Structure-activity relationship studies on isoindoline inhibitors of dipeptidyl peptidases 8 and 9 (DPP8, DPP9): is DPP8-selectivity an attainable goal?

  Journal of medicinal chemistry 20110825

• Diels-Alder cycloaddition of chiral nonracemic 2,5-diketopiperazine dienes.

  Organic letters 20110819

• A dedicated glutathione S-transferase mediates carbon-sulfur bond formation in gliotoxin biosynthesis.

  Journal of the American Chemical Society 20110817

• N-substituted homopiperazine barbiturates as gelatinase inhibitors.

  Bioorganic & medicinal chemistry 20110815

• Intestinal nematode infections in Romania: an epidemiological study and brief review of literature.

  Vector borne and zoonotic diseases (Larchmont, N.Y.) 20110801

• Anthelmintic activities of chloroform and methanol extracts of Buchholzia coriacea Engler seed.

  Parasitology research 20110801

• Fertility preservation in women--a practical guide to preservation techniques and therapeutic strategies in breast cancer, Hodgkin's lymphoma and borderline ovarian tumours by the fertility preservation network FertiPROTEKT.

  Archives of gynecology and obstetrics 20110801

• Puberty suppression in a gender-dysphoric adolescent: a 22-year follow-up.

  Archives of sexual behavior 20110801

• Tandem mass spectrometry measurement of the collision products of carbamate anions derived from CO2 capture sorbents: paving the way for accurate quantitation.

  Journal of the American Society for Mass Spectrometry 20110801

• Hexachloridobis-{μ-2-(piperazin-1-yl)-N-[1-(2-pyrid-yl)ethyl-idene]ethanamine}-trizinc dihydrate.

  Acta crystallographica. Section E, Structure reports online 20110801

• 3,8-Dimethyl-quinazoline-2,4(1H,3H)-dione.

  Acta crystallographica. Section E, Structure reports online 20110801

• 1-(2-Hy-droxy-eth-yl)-4-[3-(2-trifluoro-methyl-9H-thioxanthen-9-yl-idene)prop-yl]piperazine-1,4-diium dichloride: the dihydro-chloride salt of flupentixol.

  Acta crystallographica. Section E, Structure reports online 20110801

• 2-[4-(4-Methylphenylsulfonyl)piperazin-1-yl]-1-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)ethanone.

  Acta crystallographica. Section E, Structure reports online 20110801

• Molecular dynamics simulation studies of absorption in piperazine activated MDEA solution.

  Physical chemistry chemical physics : PCCP 20110728

• Benzyl derivatives with in vitro binding affinity for human opioid and cannabinoid receptors from the fungus Eurotium repens.

  Journal of natural products 20110722

• Effect of the gonadotropin-releasing hormone analogue triptorelin on the occurrence of chemotherapy-induced early menopause in premenopausal women with breast cancer: a randomized trial.

  JAMA 20110720

• Progress in structure based drug design for G protein-coupled receptors.

  Journal of medicinal chemistry 20110714

• Biosynthetic chlorination of the piperazate residue in kutzneride biosynthesis by KthP.

  Biochemistry 20110712

• Design, synthesis and biological activity evaluation of arylpiperazine derivatives for the treatment of neuropathic pain.

  Molecules (Basel, Switzerland) 20110707

• A comparison of the effect of short-term aromatase inhibitor (letrozole) and GnRH agonist (triptorelin) versus case control on pregnancy rate and symptom and sign recurrence after laparoscopic treatment of endometriosis.

  Archives of gynecology and obstetrics 20110701

• Identification of biotransformation products of macrolide and fluoroquinolone antimicrobials in membrane bioreactor treatment by ultrahigh-performance liquid chromatography/quadrupole time-of-flight mass spectrometry.

  Analytical and bioanalytical chemistry 20110701

• Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors.

  Nature chemical biology 20110701

• Discovery and optimization of potent and selective benzonaphthyridinone analogs as small molecule mTOR inhibitors with improved mouse microsome stability.

  Bioorganic & medicinal chemistry letters 20110701

• Functional pectoralis minor muscle flap transplantation for reconstruction of thumb opposition: an anatomic study and clinical applications.

  Microsurgery 20110701

• Dichlorido(4-meth-oxy-2-{[2-(piperazin-4-ium-1-yl)eth-yl]imino-meth-yl}phenol-ate)cadmium.

  Acta crystallographica. Section E, Structure reports online 20110701

• Bis(1-methyl-piperazine-1,4-diium) tetra-bromidocuprate(II).

  Acta crystallographica. Section E, Structure reports online 20110701

• Bis(1-methyl-piperazine-1,4-diium) tetra-chloridocuprate(II).

  Acta crystallographica. Section E, Structure reports online 20110701

• Piperazine-1,4-diium bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O)cobaltate(II) tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20110701

• 1,4-Dihydro-quinoxaline-2,3-dione-5-nitro-isophthalic acid-water (1/1/1).

  Acta crystallographica. Section E, Structure reports online 20110701

• Opipramol.

  Acta crystallographica. Section E, Structure reports online 20110701

• 4-{[5-(4-Chloro-phen-yl)-1-(4-fluoro-phen-yl)-1H-pyrazol-3-yl]carbon-yl}-N-ethyl-piperazine-1-carboxamide.

  Acta crystallographica. Section E, Structure reports online 20110701

• 1,1'-(Piperazine-1,4-di-yl)dipropan-2-ol.

  Acta crystallographica. Section E, Structure reports online 20110701

• Diagnostic NH and OH vibrations for oxazolone and diketopiperazine structures: b2 from protonated triglycine.

  Journal of the American Society for Mass Spectrometry 20110701

• Linking of sensor molecules with amino groups to amino-functionalized AFM tips.

  Bioconjugate chemistry 20110615

• Discriminating octahedral transition metal ions: highly selective tripodal tris-(2,2'-bipyridine) functionalized piperazine cyclophane receptor for Cu2+ ions.

  Dalton transactions (Cambridge, England : 2003) 20110607

• A vanadium (VO2+) metal-organic framework: selective vapor adsorption, magnetic properties, and use as a precursor for a polyoxovanadate.

  Inorganic chemistry 20110606

• Singular value decomposition analysis of the torsional angles of dopamine reuptake inhibitor GBR 12909 analogs: effect of force field and charges.

  Journal of molecular modeling 20110601

• Preclinical profile of a novel metabotropic glutamate receptor 5 positive allosteric modulator.

  European journal of pharmacology 20110601

• Aryl piperazine and pyrrolidine as antimalarial agents. Synthesis and investigation of structure-activity relationships.

  Experimental parasitology 20110601

• Itaconic acid derivatives and diketopiperazine from the marine-derived fungus Aspergillus aculeatus CRI322-03.

  Phytochemistry 20110601

• Understanding the binding mode and function of BMS-488043 against HIV-1 viral entry.

  Proteins 20110601

• LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.

  Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601

• Modelling of serotonin reuptake inhibitory and histamine H₃antagonistic activity of piperazine and diazepane amides: QSAR rationales for co-optimization of the activity profiles.

  SAR and QSAR in environmental research 20110601

• Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors.

  Current medicinal chemistry 20110601

• Potential drug development candidates for human soil-transmitted helminthiases.

  PLoS neglected tropical diseases 20110601

• Nocardioazines: a novel bridged diketopiperazine scaffold from a marine-derived bacterium inhibits P-glycoprotein.

  Organic letters 20110520

• Light-responsive threadlike micelles as drag reducing fluids with enhanced heat-transfer capabilities.

  Langmuir : the ACS journal of surfaces and colloids 20110517

• SAR studies on a series of N-benzyl-4-heteroaryl-1-(phenylsulfonyl)piperazine-2-carboxamides: potent inhibitors of the polymerase enzyme (NS5B) of the hepatitis C virus.

  Bioorganic & medicinal chemistry letters 20110515

• Synthesis of homoveratric acid-imprinted polymers and their evaluation as selective separation materials.

  Molecules (Basel, Switzerland) 20110505

• New potent biphalin analogues containing p-fluoro-L-phenylalanine at the 4,4' positions and non-hydrazine linkers.

  Amino acids 20110501

• Traceless synthesis of diketopiperazine fused tetrahydro-β-carbolines on soluble polymer support.

  Molecular diversity 20110501

• Spectral-luminescent properties and molecular orbital treatment of some mono- and difluoroquinolones.

  Journal of fluorescence 20110501

• The pattern of arrangement of the lumbrical muscles in an African population.

  Clinical anatomy (New York, N.Y.) 20110501

• Discovery of PF-00217830: aryl piperazine napthyridinones as D2 partial agonists for schizophrenia and bipolar disorder.

  Bioorganic & medicinal chemistry letters 20110501

• Synthesis and structure-activity relationship of tricyclic carboxylic acids as novel anti-histamines.

  Bioorganic & medicinal chemistry 20110501

• Synthesis and biological evaluation of novel 4-benzylpiperazine ligands for sigma-1 receptor imaging.

  Bioorganic & medicinal chemistry 20110501

• Synthesis and structure-activity relationships of a novel class of dithiocarbamic acid esters as anticancer agent.

  Archiv der Pharmazie 20110501

• Impact of methylation of acyl glucuronide metabolites on incurred sample reanalysis evaluation: ramiprilat case study.

  Bioanalysis 20110501

• [Surgical treatment of stiff metacarpophalangeal joint after hand injury].

  Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20110501

• A comparison of the accuracy of ulnar versus median nerve stimulation for neuromuscular monitoring.

  Korean journal of anesthesiology 20110501

• Piperazine-1,4-diium pyridine-2,3-dicarboxyl-ate methanol monosolvate.

  Acta crystallographica. Section E, Structure reports online 20110501

• In vitro electrophysiological investigations of the acute effects of linezolid and novel oxazolidinones on central nervous system neurons.

  Neuroscience 20110428

• Oxidation of antibiotics during water treatment with potassium permanganate: reaction pathways and deactivation.

  Environmental science & technology 20110415

• Alkyl piperidine and piperazine hydroxamic acids as HDAC inhibitors.

  Bioorganic & medicinal chemistry letters 20110415

• Synthesis, crystal structures and magnetic properties of dinuclear copper(II) compounds with NNO tridentate Schiff base ligands and bridging aliphatic diamine and aromatic diimine linkers.

  Dalton transactions (Cambridge, England : 2003) 20110407

• Plasmid-mediated quinolone resistance: an update.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110401

• Chemical absorption of carbon dioxide with asymmetrically heated polytetrafluoroethylene membranes.

  Journal of environmental management 20110401

• Pharmacokinetics and metabolism of BIBF 1120 after oral dosing to healthy male volunteers.

  Xenobiotica; the fate of foreign compounds in biological systems 20110401

• Extracellular polymeric substances from Shewanella sp. HRCR-1 biofilms: characterization by infrared spectroscopy and proteomics.

  Environmental microbiology 20110401

• Purification and structure elucidation of three naturally bioactive molecules from the new terrestrial Streptomyces sp. TN17 strain.

  Natural product research 20110401

• Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus.

  European journal of medicinal chemistry 20110401

• Statistically disordered short hydrogen bonds in (pipzH2)(cdoH)2 and a comparison with (pipzH2)(cdo)·H2O (pipz is piperazine and cdoH2 is chelidonic acid).

  Acta crystallographica. Section C, Crystal structure communications 20110401

• Selective release of the digital extensor hood to reduce intrinsic tightness in tetraplegia.

  Journal of plastic surgery and hand surgery 20110401

• [Comparison of human chorionic gonadotropin (Pregnyl 10 000 IU i.m.) versus GnRH agonist (triptorelin 0,2 mg s.c.) for final oocytes maturation in the same egg donors--clinical and embryological characteristics].

  Ceska gynekologie 20110401

• Tris(piperazine-1,4-diium) bis-[hexa-chloridoindate(III)] tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20110401

• 1-(2,5-Dimethyl-phen-yl)piperazine-1,4-diium tetra-chloridozincate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110401

• Structure and magnetism of new hybrid cobalt hydroxide materials built from decorated brucite layers.

  Dalton transactions (Cambridge, England : 2003) 20110328

• Zwitterionic CRTh2 antagonists.

  Journal of medicinal chemistry 20110324

• Piperazines for peptide carboxyl group derivatization: effect of derivatization reagents and properties of peptides on signal enhancement in matrix-assisted laser desorption/ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20110315

• Modeling CO2 mass transfer in amine mixtures: PZ-AMP and PZ-MDEA.

  Environmental science & technology 20110315

• Multiresidue determination of ultratrace levels of fluoroquinolone antimicrobials in drinking and aquaculture water samples by automated online molecularly imprinted solid phase extraction and liquid chromatography.

  Analytical chemistry 20110315

• [Clinical values of triptorelin stimulating test in assessing hypothalamus-pituitary-gonad axis function in male patients with hypothalamus-pituitary-gonad axis disorders].

  Zhonghua yi xue za zhi 20110315

• Crystallographic characterisation of Ti(IV) piperazine complexes and their exploitation for the ring opening polymerisation of rac-lactide.

  Dalton transactions (Cambridge, England : 2003) 20110307

• Birth after TESE-ICSI in a man with hypogonadotropic hypogonadism and congenital adrenal hypoplasia linked to a DAX-1 (NR0B1) mutation.

  Human reproduction (Oxford, England) 20110301

• II. SAR studies of pyridyl-piperazinyl-piperidine derivatives as CXCR3 chemokine antagonists.

  Bioorganic & medicinal chemistry letters 20110301

• Discovery of novel (4-piperidinyl)-piperazines as potent and orally active acetyl-CoA carboxylase 1/2 non-selective inhibitors: F-Boc and triF-Boc groups are acid-stable bioisosteres for the Boc group.

  Bioorganic & medicinal chemistry 20110301

• A case of primary aldosteronism in pregnancy: do LH and GNRH receptors have a potential role in regulating aldosterone secretion?

  European journal of endocrinology 20110301

• 5-Nitroimidazole-based 1,3,4-thiadiazoles: heterocyclic analogs of metronidazole as anti-Helicobacter pylori agents.

  Archiv der Pharmazie 20110301

• Identification of Ascaridia numidae in guinea fowl (Numida meleagris) and association with elevated mortality.

  Avian diseases 20110301

• Poly[[piperazine-1,4-dium [diaqua-tetra-kis-(μ-sulfanediyldiacetato)-dicerate(III)]] trihydrate].

  Acta crystallographica. Section E, Structure reports online 20110301

• Piperazinediium tetra-chloridocadmate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110301

• Ethyl 4-[2-(3,5-dimethyl-4-oxo-2,6-diphenyl-piperidin-1-yl)-2-oxoeth-yl]piperazine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20110301

• 2-{2-[4-(4-Fluoro-phen-yl)piperazin-1-yl]-2-oxoeth-yl}-6-(morpholin-4-yl)-4-phenyl-pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20110301

• (E)-1-{4-[Bis(4-meth-oxy-phen-yl)meth-yl]piperazin-1-yl}-3-(4-fluoro-phen-yl)prop-2-en-1-one.

  Acta crystallographica. Section E, Structure reports online 20110301

• 2-Chloro-1-[4-(2-fluoro-benz-yl)piperazin-1-yl]ethanone.

  Acta crystallographica. Section E, Structure reports online 20110301

• History, epidemiology and control of filariasis.

  Tropical medicine and health 20110301

• 9-Piperazine substituted perylene-3,4-dicarboximide as a fluorescent probe in ratiometric analysis.

  Chemical communications (Cambridge, England) 20110227

• Synthesis of new visnagen and khellin furochromone pyrimidine derivatives and their anti-inflammatory and analgesic activity.

  Molecules (Basel, Switzerland) 20110225

• Separation and structural elucidation of a novel analogue of vardenafil included as an adulterant in a dietary supplement by liquid chromatography-electrospray ionization mass spectrometry, infrared spectroscopy and nuclear magnetic resonance spectroscopy.

  Journal of pharmaceutical and biomedical analysis 20110220

• Synthesis-guided structure revision of the sarcodonin, sarcoviolin, and hydnellin natural product family.

  The Journal of organic chemistry 20110218

• Copolymers sensitive to temperature and pH in water and in water+oil mixtures: A DSC, ITC and volumetric study.

  Journal of colloid and interface science 20110215

• Tissue distribution and characterization of drug-related material in rats and dogs after repeated oral administration of casopitant.

  Drug metabolism and disposition: the biological fate of chemicals 20110201

• The anti-ischemic and anti-anginal properties of statins.

  Current atherosclerosis reports 20110201

• Molecular modeling study and synthesis of quinazolinone-arylpiperazine derivatives as α1-adrenoreceptor antagonists.

  European journal of medicinal chemistry 20110201

• The effects of the 4-(4-Methylpiperazine)phenyl group on nucleosides and oligonucleotides: cellular delivery, detection, and stability.

  Chemistry, an Asian journal 20110201

• Studies of tricyclic piperazine/piperidine furnished molecules as novel integrin αvβ3/αIIbβ3 dual antagonists using 3D-QSAR and molecular docking.

  Journal of molecular graphics & modelling 20110201

• Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds.

  Nuclear medicine and biology 20110201

• A low-tech analytical method for diethylcarbamazine citrate in medicated salt.

  PLoS neglected tropical diseases 20110201

• Protection of flunarizine on cerebral mitochondria injury induced by cortical spreading depression under hypoxic conditions.

  The journal of headache and pain 20110201

• 1-Methyl-piperazine-1,4-diium dipicrate.

  Acta crystallographica. Section E, Structure reports online 20110201

• Enrofloxacinium picrate.

  Acta crystallographica. Section E, Structure reports online 20110201

• Lomefloxacinium picrate.

  Acta crystallographica. Section E, Structure reports online 20110201

• Cinnarizinium dipicrate.

  Acta crystallographica. Section E, Structure reports online 20110201

• Fragmentation patterns of novel dithiocarbamate derivatives with pharmaceutical activity under electrospray ionization tandem mass spectrometry conditions.

  Rapid communications in mass spectrometry : RCM 20110130

• DHF-18, a new synthetic flavonoid, induced a mitochondrial-mediated apoptosis of hepatocarcinoma cells in vivo and in vitro.

  European journal of pharmacology 20110125

• Rapid room temperature synthesis of electrocatalytically active Au nanostructures.

  Journal of colloid and interface science 20110115

• Synchronization of ovulation and fertility in weaned sows treated with intravaginal triptorelin is influenced by timing of administration and follicle size.

  Theriogenology 20110115

• NMR spectroscopy and surface tension measurements applied to the study of self-association of casopitant mesylate, a novel NK1 antagonist.

  Journal of pharmaceutical and biomedical analysis 20110105

• Regioselective ring-opening of amino acid-derived chiral aziridines: an easy access to cis-2,5-disubstituted chiral piperazines.

  Chemistry, an Asian journal 20110103

• Conformational analysis of piperazine and piperidine analogs of GBR 12909: stochastic approach to evaluating the effects of force fields and solvent.

  Journal of molecular modeling 20110101

• Allopregnanolone levels decrease after gonadotropin-releasing hormone analog stimulation test in girls with central precocious puberty.

  Journal of endocrinological investigation 20110101

• Interaction of novel hybrid compounds with the D3 dopamine receptor: Site-directed mutagenesis and homology modeling studies.

  Biochemical pharmacology 20110101

• 2-Arylbenzoxazoles as CETP inhibitors: raising HDL-C in cynoCETP transgenic mice.

  Bioorganic & medicinal chemistry letters 20110101

• Design, synthesis and antimycobacterial activities of 1-methyl-2-alkenyl-4(1H)-quinolones.

  Bioorganic & medicinal chemistry 20110101

• Apoptosis-inducing effect of diketopiperazine disulfides produced by Aspergillus sp. KMD 901 isolated from marine sediment on HCT116 colon cancer cell lines.

  Journal of applied microbiology 20110101

• Changes in the mucosal barrier during acute and chronic Trichuris muris infection.

  Parasite immunology 20110101

• The distributional nexus of choroid plexus to cerebrospinal fluid, ependyma and brain: toxicologic/pathologic phenomena, periventricular destabilization, and lesion spread.

  Toxicologic pathology 20110101

• Cost-effectiveness analysis of LHRH agonists in the treatment of metastatic prostate cancer in Italy.

  Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101

• New diketopiperazine derivatives isolated from sea urchin-derived bacillus sp.

  Chemical & pharmaceutical bulletin 20110101

• A case of chlorpheniramine maleate-induced hypersensitivity with aspirin intolerance.

  Allergy, asthma & immunology research 20110101

• An 82-year-old Caucasian man with a ductal prostate adenocarcinoma with unusual cystoscopic appearance: a case report.

  Journal of medical case reports 20110101

• β-Elemene piperazine derivatives induce apoptosis in human leukemia cells through downregulation of c-FLIP and generation of ROS.

  PloS one 20110101

• Towards electrosynthesis in shewanella: energetics of reversing the mtr pathway for reductive metabolism.

  PloS one 20110101

• AGEs secreted by bacteria are involved in the inflammatory response.

  PloS one 20110101

• Alpha-COPI coatomer protein is required for rough endoplasmic reticulum whorl formation in mosquito midgut epithelial cells.

  PloS one 20110101

• Multi-finger coordination in healthy subjects and stroke patients: a mathematical modelling approach.

  Journal of neuroengineering and rehabilitation 20110101

• 2-Meth-oxy-4-[(4-methyl-piperazin-1-yl)imino-meth-yl]phenol.

  Acta crystallographica. Section E, Structure reports online 20110101

• N-(4-{4-[2-(Trifluoro-meth-oxy)phen-yl]piperazin-1-yl}but-yl)thio-phene-2-carboxamide dihydrate.

  Acta crystallographica. Section E, Structure reports online 20110101

• 2-[4-(2-Meth-oxy-phen-yl)piperazin-1-yl]-N-(pyridin-2-yl)acetamide.

  Acta crystallographica. Section E, Structure reports online 20110101

• Piperazine-1,4-diium bis-(hydrogen 2-propyl-1H-imidazole-4,5-dicarbox-ylate) monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110101

• 2-Amino-4-methyl-pyridinium 6-carb-oxy-pyridine-2-carboxyl-ate methanol monosolvate.

  Acta crystallographica. Section E, Structure reports online 20110101

• A novel structural framework for α(1A/D)-adrenoceptor selective antagonists identified using subtype selective pharmacophores.

  PloS one 20110101

• Polyamide-scorpion cyclam lexitropsins selectively bind AT-rich DNA independently of the nature of the coordinated metal.

  PloS one 20110101

• Membrane sealant Poloxamer P188 protects against isoproterenol induced cardiomyopathy in dystrophin deficient mice.

  BMC cardiovascular disorders 20110101

• Muc5b is the major polymeric mucin in mucus from thoroughbred horses with and without airway mucus accumulation.

  PloS one 20110101

• Gonadotropin-dependent precocious puberty: neoplastic causes and endocrine considerations.

  International journal of pediatric endocrinology 20110101

• Fixed dystonia in complex regional pain syndrome: a descriptive and computational modeling approach.

  BMC neurology 20110101

• Clinical utility of tibial motor and sensory nerve conduction studies with motor recording from the flexor hallucis brevis: a methodological and reliability study.

  Journal of foot and ankle research 20110101

• Encephalopathy as a presenting feature of ascariasis in a child.

  Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 20110101

• Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review.

  Journal of pharmacy & bioallied sciences 20110101

• Quinolone resistance: much more than predicted.

  Frontiers in microbiology 20110101

• Letrozole and norethisterone acetate versus letrozole and triptorelin in the treatment of endometriosis related pain symptoms: a randomized controlled trial.

  Reproductive biology and endocrinology : RB&E 20110101

• Use of aromatase inhibitors to treat endometriosis-related pain symptoms: a systematic review.

  Reproductive biology and endocrinology : RB&E 20110101

• Sustained release of VEGF from PLGA nanoparticles embedded thermo-sensitive hydrogel in full-thickness porcine bladder acellular matrix.

  Nanoscale research letters 20110101

• Effect of potassium channel openers on intraocular pressure in rabbits.

  Indian journal of pharmacology 20110101

• Effect of piperine in the regulation of obesity-induced dyslipidemia in high-fat diet rats.

  Indian journal of pharmacology 20110101

• An unusual bifid origin of 1st lumbrical muscle of hand: anatomical and clinical perspectives.

  La Clinica terapeutica 20110101

• Phylogenetic identification of fungi isolated from the marine sponge Tethya aurantium and identification of their secondary metabolites.

  Marine drugs 20110101

• Development of a rapid LC-MS/MS method for direct urinalysis of designer drugs.

  Drug testing and analysis 20110101

• Current awareness of piperazines: pharmacology and toxicology.

  Drug testing and analysis 20110101

• HelmCoP: an online resource for helminth functional genomics and drug and vaccine targets prioritization.

  PloS one 20110101

• Synthesis and Biological Evaluation of New 3-Phenyl-1-[(4-arylpiperazin-1-yl)alkyl]-piperidine-2,6-diones.

  Scientia pharmaceutica 20110101

• Rectal endometriosis causing colonic obstruction and concurrent endometriosis of the appendix: a case report.

  Journal of medical case reports 20110101

• A preliminary study of the microbial resources and their biological activities of the East china sea.

  Evidence-based complementary and alternative medicine : eCAM 20110101

• Sipuleucel-T for therapy of asymptomatic or minimally symptomatic, castrate-refractory prostate cancer: an update and perspective among other treatments.

  OncoTargets and therapy 20110101

• Differences in treatment patterns among patients with castration-resistant prostate cancer treated by oncologists versus urologists in a US managed care population.

  Cancer management and research 20110101

• Dienogest in long-term treatment of endometriosis.

  International journal of women's health 20110101

• A randomized clinical trial to compare levonorgestrel-releasing intrauterine system (Mirena) vs trans-cervical endometrial resection for treatment of menorrhagia.

  International journal of women's health 20110101

• Six-month gonadotropin releasing hormone (GnRH) agonist depots provide efficacy, safety, convenience, and comfort.

  Cancer management and research 20110101

• The muscle satellite cell at 50: the formative years.

  Skeletal muscle 20110101

• The cadaver of a Caucasian man with a supernumerary fourth dorsal interosseous muscle in the right hand: a case report.

  Journal of medical case reports 20110101

• Efficacy of Leuprolide Acetate 1-Month Depot for Central Precocious Puberty (CPP): Growth Outcomes During a Prospective, Longitudinal Study.

  International journal of pediatric endocrinology 20110101

• Neuromuscular electrical stimulation and biofeedback therapy may improve endometrial growth for patients with thin endometrium during frozen-thawed embryo transfer: a preliminary report.

  Reproductive biology and endocrinology : RB&E 20110101

• Nanocarriers for nitric oxide delivery.

  Journal of drug delivery 20110101

• Neglected disease - african sleeping sickness: recent synthetic and modeling advances.

  Scientia pharmaceutica 20110101

• A Rapid, Stability Indicating RP-UPLC Method for Simultaneous Determination of Ambroxol Hydrochloride, Cetirizine Hydrochloride and Antimicrobial Preservatives in Liquid Pharmaceutical Formulation.

  Scientia pharmaceutica 20110101

• Current and emerging treatments for uterine myoma - an update.

  International journal of women's health 20110101

• Studies on the anthelmintic property of aminobenzylated mannich bases.

  Journal of young pharmacists : JYP 20110101

• Cross sensitivity between ciprofloxacin and levofloxacin for an immediate hypersensitivity reaction.

  Journal of pharmacology & pharmacotherapeutics 20110101

• Interactions between worms and malaria: good worms or bad worms?

  Malaria journal 20110101

• Engineered multifunctional nanotools for biological applications.

  Methods in molecular biology (Clifton, N.J.) 20110101

• Investigation of the structure requirement for 5-HT₆ binding affinity of arylsulfonyl derivatives: a computational study.

  International journal of molecular sciences 20110101

• Hydroxyzine-induced acute generalized exanthematous pustulosis: an uncommon side effect of a common drug.

  Indian journal of dermatology 20110101

• Treating nausea and vomiting in palliative care: a review.

  Clinical interventions in aging 20110101

• Antifungal activity of microbial secondary metabolites.

  PloS one 20110101

• Transgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx mice.

  Skeletal muscle 20110101

• Degloving injuries of the hand.

  Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India 20110101

• Compressive neuropathy in the upper limb.

  Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India 20110101

• A reaction-diffusion model to capture disparity selectivity in primary visual cortex.

  PloS one 20110101

• Sugar substitutes: Health controversy over perceived benefits.

  Journal of pharmacology & pharmacotherapeutics 20110101

• Gonadotropin releasing hormone agonists: Expanding vistas.

  Indian journal of endocrinology and metabolism 20110101

• Direct evidence for the co-expression of URP and GnRH in a sub-population of rat hypothalamic neurones: anatomical and functional correlation.

  PloS one 20110101

• GnRH receptor activation competes at a low level with growth signaling in stably transfected human breast cell lines.

  BMC cancer 20110101

• Cytotoxic and anthelmintic potential of crude saponins isolated from Achillea Wilhelmsii C. Koch and Teucrium Stocksianum boiss.

  BMC complementary and alternative medicine 20110101

• New algorithm for OHSS prevention.

  Reproductive biology and endocrinology : RB&E 20110101

• Eudragit nanoparticles containing genistein: formulation, development, and bioavailability assessment.

  International journal of nanomedicine 20110101

• Chitosan derivatives with antimicrobial, antitumour and antioxidant activities--a review.

  Current pharmaceutical design 20110101

• The Response of Shewanella oneidensis MR-1 to Cr(III) Toxicity Differs from that to Cr(VI).

  Frontiers in microbiology 20110101

• A comparative study of the anthelmintic potential of cleome viscosa L. And cleome burmanni w. And a.

  Indian journal of pharmaceutical sciences 20110101

• Determination of anthelmintic activity of the leaf and bark extract of tamarindus indica linn.

  Indian journal of pharmaceutical sciences 20110101

• Anthelmintic effect of Euphorbia prostrata Ait. extracts.

  Indian journal of pharmacology 20110101

• Identification of major degradation products of ketoconazole.

  Scientia pharmaceutica 20110101

• Quinazolinobenzodiazepine Derivatives, Novobenzomalvins A-C: Fibronectin Expression Regulators from Aspergillus novofumigatus.

  Scientia pharmaceutica 20110101

• Unique concurrent appearance of two rare conditions in a young girl: central precocious puberty due to hypothalamic hamartoma and uncommon type of diabetes.

  Journal of pediatric endocrinology & metabolism : JPEM 20110101

• Are prescribing doctors sensitive to the price that their patients have to pay in the Spanish National Health System?

  BMC health services research 20110101

• Docking studies on novel analogues of 8 methoxy fluoroquinolones against GyrA mutants of Mycobacterium tuberculosis.

  BMC structural biology 20110101

• A new diketopiperazine, cyclo-(4-S-hydroxy-R-proline-R-isoleucine), from an Australian specimen of the sponge Stelletta sp.

  Marine drugs 20110101

• [Histrelin acetate--the first once yearly LHRH agonist].

  Lijecnicki vjesnik 20110101

• Qualitative analysis of controlled release ciprofloxacin/carbopol 934 mucoadhesive suspension.

  Journal of advanced pharmaceutical technology & research 20110101

• Solid-phase synthesis of functionalized bis-peptides.

  Biopolymers 20110101

• Physiology and pathophysiology of CLC-1: mechanisms of a chloride channel disease, myotonia.

  Journal of biomedicine & biotechnology 20110101

• 3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors.

  International journal of molecular sciences 20110101

• Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer.

  Drug, healthcare and patient safety 20110101

• Microwave-assisted Heterocyclic Dicarboxylic Acids as Potential Antifungal and Antibacterial Drugs.

  Indian journal of pharmaceutical sciences 20110101

• In silico approach to screen compounds active against parasitic nematodes of major socio-economic importance.

  BMC bioinformatics 20110101

• Molecular-field-based three-dimensional similarity studies on quinoline-based CNS active agents.

  ISRN pharmaceutics 20110101

• Pore with gate: modulating hydrogen storage in metal-organic framework materials via cation exchange.

  Faraday discussions 20110101

• A Sensitive RP-HPLC Method for Simultaneous Estimation of Diethylcarbamazine and Levocetirizine in Tablet Formulation.

  Indian journal of pharmaceutical sciences 20110101

• Buclizine.

  Profiles of drug substances, excipients, and related methodology 20110101

• Chronic inflammation in cancer development.

  Frontiers in immunology 20110101

• Inhibition of DNA gyrase by levofloxacin and related fluorine-containing heterocyclic compounds.

  Acta naturae 20110101

• N-Nitrosopiperazines form at high pH in post-combustion capture solutions containing piperazine: a low-energy collisional behaviour study.

  Rapid communications in mass spectrometry : RCM 20101230

• 4-aryl piperazine and piperidine amides as novel mGluR5 positive allosteric modulators.

  Bioorganic & medicinal chemistry letters 20101215

• Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.

  Bioorganic & medicinal chemistry letters 20101215

• Ranolazine--treatment of ventricular tachycardia and symptomatic ventricular premature beats in ischemic cardiomyopathy.

  Pacing and clinical electrophysiology : PACE 20101201

• Oxidation of fluoroquinolone antibiotics and structurally related amines by chlorine dioxide: Reaction kinetics, product and pathway evaluation.

  Water research 20101201

• Structures of cyclic dipeptides: an X-ray and computational study of cis- and trans-cyclo(Pip-Phe), cyclo(Pro-Phe) and their N-methyl derivatives.

  Acta crystallographica. Section B, Structural science 20101201

• Phase II trial of combination of pegylated liposomal doxorubicin, cisplatin, and infusional 5-fluorouracil (CCF) plus trastuzumab as preoperative treatment for locally advanced and inflammatory breast cancer.

  Clinical breast cancer 20101201

• Levocetirizinium dipicrate.

  Acta crystallographica. Section E, Structure reports online 20101201

• Tetra-phenyl piperazine-1,4-diyldiphos-pho-nate.

  Acta crystallographica. Section E, Structure reports online 20101201

• Piperazine-2,3,5,6-tetra-one.

  Acta crystallographica. Section E, Structure reports online 20101201

• 1,4-Dibenzyl-piperazine.

  Acta crystallographica. Section E, Structure reports online 20101201

• Half-dose, long-acting gonadotropin-releasing hormone agonist (Diphereline) is comparable with daily injections of short-acting gonadotropin-releasing hormone agonist (Suprefact) in IVF/ICSI cycles.

  Archives of medical science : AMS 20101201

• Dienogest: a review of its use in the treatment of endometriosis.

  Drugs 20101112

• Correlation of electronic structures of three cyclic dipeptides with their photoemission spectra.

  The Journal of chemical physics 20101107

• Anabolic steroids purchased on the Internet as a cause of prolonged hypogonadotropic hypogonadism.

  Fertility and sterility 20101101

• Metabolism, pharmacokinetics, and excretion of the 5-hydroxytryptamine1b receptor antagonist elzasonan in humans.

  Drug metabolism and disposition: the biological fate of chemicals 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examples.

  Archives of toxicology 20101101

• Plasmid-mediated quinolone resistance among non-Typhi Salmonella enterica isolates, USA.

  Emerging infectious diseases 20101101

• Aqua-{4,4',6,6'-tetra-fluoro-2,2'-[(piperazine-1,4-di-yl)dimethyl-ene]diphenolato}copper(II).

  Acta crystallographica. Section E, Structure reports online 20101101

• 1-[4-(4-Nitro-phen-yl)piperazin-1-yl]-2-(4,5,6,7-tetra-hydro-thieno[3,2-c]pyridin-5-yl)ethanone.

  Acta crystallographica. Section E, Structure reports online 20101101

• 1,4-Diazo-niacyclo-hexane bis-(3-carb-oxy-pyrazine-2-carboxyl-ate) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20101101

• Tetra-imidazolium piperazinediium bis-(benzene-1,3,5-tricarboxyl-ate) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20101101

• Synthesis and crystal structure from X-ray powder diffraction data of two zirconium diphosphonates containing piperazine groups.

  Inorganic chemistry 20101018

• N-phenyl-N'-[4-(5H-pyrrolo[3,2-d]pyrimidin-4-yloxy)phenyl]ureas as novel inhibitors of VEGFR and FGFR kinases.

  Bioorganic & medicinal chemistry 20101015

• A unified strategy targeting the thiodiketopiperazine mycotoxins exserohilone, gliotoxin, the epicoccins, the epicorazines, rostratin A and aranotin.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20101011

• Re-determination of the structure of an anionic oxo-vanadium arsenate framework.

  Dalton transactions (Cambridge, England : 2003) 20101007

• Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.

  Cancer letters 20101001

• Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice.

  Acta neuropathologica 20101001

• Use of a rhodamine-based bifunctional probe in N-terminal specific labeling of Thermomyces lanuginosus xylanase.

  Molecular bioSystems 20101001

• Metabolic disposition of casopitant, a potent neurokinin-1 receptor antagonist, in mice, rats, and dogs.

  Drug metabolism and disposition: the biological fate of chemicals 20101001

• Physiology and biochemistry of reduction of azo compounds by Shewanella strains relevant to electron transport chain.

  Applied microbiology and biotechnology 20101001

• Tracking bacterial infection of macrophages using a novel red-emission pH sensor.

  Analytical and bioanalytical chemistry 20101001

• Design, synthesis and docking studies on phenoxy-3-piperazin-1-yl-propan-2-ol derivatives as protein tyrosine phosphatase 1B inhibitors.

  Bioorganic & medicinal chemistry letters 20101001

• Calculation of muscle maximal shortening velocity by extrapolation of the force-velocity relationship: afterloaded versus isotonic release contractions.

  Canadian journal of physiology and pharmacology 20101001

• Patterning of pH sensitive fluorescent bipyridazine derivatives.

  Journal of nanoscience and nanotechnology 20101001

• (R)-2-Methyl-piperazine-1,4-diium diaqua-tetra-chloridoferrate(II).

  Acta crystallographica. Section E, Structure reports online 20101001

• 4-{[5-(4-Chloro-phen-yl)-1-(4-fluoro-phen-yl)-1H-pyrazol-3-yl]carbon-yl}-N-(4-cyano-phen-yl)piperazine-1-carboxamide.

  Acta crystallographica. Section E, Structure reports online 20101001

• 1,4-Bis(carb-oxy-meth-yl)piperazine-1,4-diium bis-(dihydrogen phosphate) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20101001

• Piperazine-1,4-diium bis-(2-carb-oxy-1H-pyrazole-4-carboxyl-ate) tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20101001

• tert-Butyl 4-{[5-(4-chloro-phen-yl)-1-(4-fluoro-phen-yl)-1H-pyrazol-3-yl]carbon-yl}piperazine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20101001

• N-{2-[4-(2-Meth-oxy-phen-yl)piperazin-1-yl]eth-yl}-4-nitro-N-(2-pyrid-yl)benzamide.

  Acta crystallographica. Section E, Structure reports online 20101001

• Antileukemic Effects of Novel First- and Second-Generation FLT3 Inhibitors: Structure-Affinity Comparison.

  Genes & cancer 20101001

• Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples.

  Journal of analytical toxicology 20101001

• Species-dependent degradation of ciprofloxacin in a membrane anodic Fenton system.

  Journal of agricultural and food chemistry 20100922

• Synthesis and iron sequestration equilibria of novel exocyclic 3-hydroxy-2-pyridinone donor group siderophore mimics.

  Inorganic chemistry 20100920

• Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds.

  Bioorganic & medicinal chemistry 20100915

• Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands.

  Bioorganic & medicinal chemistry letters 20100915

• Synthesis of polyhydroxylated aromatics having amidation of piperazine nitrogen as HIV-1 integrase inhibitor.

  Bioorganic & medicinal chemistry letters 20100915

• Neurobiology, pharmacology, and medicinal chemistry of neuropeptide S and its receptor.

  Medicinal research reviews 20100901

• Bioactive secondary metabolites from a new terrestrial Streptomyces sp. TN262.

  Applied biochemistry and biotechnology 20100901

• Small molecule antagonists for chemokine CCR3 receptors.

  Medicinal research reviews 20100901

• Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans.

  Journal of forensic sciences 20100901

• First order phase transition and hysteresis in a cell's maintenance of the membrane potential--An essential role for the inward potassium rectifiers.

  Bio Systems 20100901

• A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities.

  European journal of medicinal chemistry 20100901

• Synthesis, biological evaluation, and structure-activity relationship study of novel cytotoxic aza-caffeic acid derivatives.

  Bioorganic & medicinal chemistry 20100901

• Macroporous molecularly imprinted monolithic polymer columns for protein recognition by liquid chromatography.

  Journal of separation science 20100901

• Pharmacokinetic characterization of the novel pulmonary delivery excipient fumaryl diketopiperazine.

  Journal of diabetes science and technology 20100901

• catena-Poly[(S)-2-methyl-piperazine-1,4-diium [[trichloridobismuthate(III)]-di-μ-chlorido]].

  Acta crystallographica. Section E, Structure reports online 20100901

• Dichlorido(2-{[2-(piperazin-4-ium-1-yl)eth-yl]imino-meth-yl}phenolate)cadmium(II).

  Acta crystallographica. Section E, Structure reports online 20100901

• Piperazine-1,4-diium bis-(perchlorate) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20100901

• Paraherquamide e.

  Acta crystallographica. Section E, Structure reports online 20100901

• 2-(2,3-Dioxoindolin-1-yl)ethyl 4-(4-nitro-phen-yl)piperazine-1-carbodithio-ate.

  Acta crystallographica. Section E, Structure reports online 20100901

• 4-Phenyl-piperazin-1-ium dihydrogen phosphate.

  Acta crystallographica. Section E, Structure reports online 20100901

• Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.

  Biochemistry 20100831

• Nocapyrones A-D, gamma-pyrones from a Nocardiopsis strain isolated from the marine sponge Halichondria panicea.

  Journal of natural products 20100827

• Synthesis and antiproliferative evaluation of certain indeno[1,2-c]quinoline derivatives. Part 2.

  Journal of medicinal chemistry 20100826

• Aqueous ethylenediamine for CO(2) capture.

  ChemSusChem 20100823

• Bicyclic sigma receptor ligands by stereoselective Dieckmann analogous cyclization of piperazinebutyrate.

  Organic & biomolecular chemistry 20100821

• Discovery of a class of diketopiperazines as antiprion compounds.

  ChemMedChem 20100802

• GnRH agonist administration at the time of implantation does not improve pregnancy outcome in intrauterine insemination cycles: a randomized controlled trial.

  Fertility and sterility 20100801

• A stereoselective synthesis of alpha-deuterium-labelled (S)-alpha-amino acids.

  Amino acids 20100801

• Polymer resins for recovery of valuable metals.

  Environmental geochemistry and health 20100801

• Determining the subjective effects of TFMPP in human males.

  Psychopharmacology 20100801

• Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands.

  Bioorganic & medicinal chemistry letters 20100801

• Further delineation of hydrophobic binding sites in dopamine D(2)/D(3) receptors for N-4 substituents on the piperazine ring of the hybrid template 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol.

  Bioorganic & medicinal chemistry 20100801

• Opipramol dipicrate.

  Acta crystallographica. Section E, Structure reports online 20100801

• (±)-2-Methyl-piperazin-1-ium perchlorate.

  Acta crystallographica. Section E, Structure reports online 20100801

• Piperazine-1,4-diium 2-(carb-oxy-meth-yl)-2-hy-droxy-butane-dioate monohydrate.

  Acta crystallographica. Section E, Structure reports online 20100801

• NMR structural studies on the covalent DNA binding of a pyrrolobenzodiazepine-naphthalimide conjugate.

  Organic & biomolecular chemistry 20100721

• Effects of shape, porosity, and operating parameters on carbon dioxide recovery in polytetrafluoroethylene membranes.

  Journal of hazardous materials 20100715

• Synthesis and cytotoxic activity of a new potential DNA bisintercalator: 1,4-Bis{3-[N-(4-chlorobenzo[g]phthalazin-1-yl)aminopropyl]}piperazine.

  Bioorganic & medicinal chemistry 20100715

• Synthesis and structure-activity relationships of N-aryl-piperidine derivatives as potent (partial) agonists for human histamine H3 receptor.

  Bioorganic & medicinal chemistry 20100715

• Studies on the anti-hepatitis C virus activity of newly synthesized tropolone derivatives: identification of NS3 helicase inhibitors that specifically inhibit subgenomic HCV replication.

  Bioorganic & medicinal chemistry 20100715

• 2-acylamino-4,6-diphenylpyridine derivatives as novel GPR54 antagonists with good brain exposure and in vivo efficacy for plasma LH level in male rats.

  Bioorganic & medicinal chemistry 20100715

• NNZ-2591, a novel diketopiperazine, prevented scopolamine-induced acute memory impairment in the adult rat.

  Behavioural brain research 20100711

• Cell-selective, apoptosis-inducing rhodium(III) crown thiaether complexes.

  ChemMedChem 20100705

• Inhibitory effect of ursolic acid derivatives on hydrogen peroxide- and glutathione-mediated degradation of hemin: a possible additional mechanism of action for antimalarial activity.

  Experimental parasitology 20100701

• Elucidating the pathways of degradation of denagliptin.

  Journal of pharmaceutical sciences 20100701

• Mutational and gene expression analysis of mtrDEF, omcA and mtrCAB during arsenate and iron reduction in Shewanella sp. ANA-3.

  Environmental microbiology 20100701

• Synthesis and structure-activity relationship study of 8-hydroxyquinoline-derived Mannich bases as anticancer agents.

  European journal of medicinal chemistry 20100701

• Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines.

  European journal of medicinal chemistry 20100701

• Purchasing 'legal highs' on the Internet--is there consistency in what you get?

  QJM : monthly journal of the Association of Physicians 20100701

• Endocrine, ovulatory and reproductive characteristics of sows treated with an intravaginal GnRH agonist.

  Animal reproduction science 20100701

• Impact of hookworm infection and deworming on anaemia in non-pregnant populations: a systematic review.

  Tropical medicine & international health : TM & IH 20100701

• Design, synthesis and anticancer activity of piperazine hydroxamates and their histone deacetylase (HDAC) inhibitory activity.

  Bioorganic & medicinal chemistry letters 20100701

• Synthesis and application of [1,2,5]triazepane and [1,2,5]oxadiazepane as versatile structural units for drug discovery.

  Chemical & pharmaceutical bulletin 20100701

• [Comparison of Alarelin and Triptorelin in the long-protocol ovulation induction in in vitro fertilization and embryo transfer].

  Zhonghua nan ke xue = National journal of andrology 20100701

• Hexa-kis-(dimethyl sulfoxide-κO)thallium(III) trinitrate.

  Acta crystallographica. Section E, Structure reports online 20100701

• N-{2-[4-(2-Meth-oxy-phen-yl)piperazin-1-yl]eth-yl}pyridin-2-amine monohydrate.

  Acta crystallographica. Section E, Structure reports online 20100701

• 3-(1-Adamant-yl)-1-{[4-(2-meth-oxy-phen-yl)piperazin-1-yl]meth-yl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione.

  Acta crystallographica. Section E, Structure reports online 20100701

• 1-Diphenyl-methyl-4-ethyl-piperazine-1,4-diium dichloride.

  Acta crystallographica. Section E, Structure reports online 20100701

• Electroanalytical characteristics of antipsychotic drug ziprasidone and its determination in pharmaceuticals and serum samples on solid electrodes.

  Talanta 20100630

• Characterization of the decaheme c-type cytochrome OmcA in solution and on hematite surfaces by small angle x-ray scattering and neutron reflectometry.

  Biophysical journal 20100616

• Second generation N-(1,2-diphenylethyl)piperazines as dual serotonin and noradrenaline reuptake inhibitors: improving metabolic stability and reducing ion channel activity.

  Bioorganic & medicinal chemistry letters 20100615

• Design and synthesis of spirotryprostatin-inspired diketopiperazine systems from prolyl spirooxoindolethiazolidine derivatives.

  Bioorganic & medicinal chemistry 20100615

• Synthesis and biological activity of oxadiazole and triazolothiadiazole derivatives as tyrosinase inhibitors.

  Bioorganic & medicinal chemistry letters 20100615

• Effect of route of administration on the pharmacokinetics and toxicokinetics of cinnarizine in dogs.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100614

• Rhodamine B piperazinoacetohydrazine: a water-soluble spectroscopic reagent for pyruvic acid labeling.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20100611

• The role of stereoactive lone pairs in templated vanadium tellurite charge density matching.

  Inorganic chemistry 20100607

• New insights into homopiperazine-based 5-HT1A/5-HT7R ligands: synthesis and biological evaluation.

  Journal of enzyme inhibition and medicinal chemistry 20100601

• Ovarian hyperresponse to luteal phase GnRH-agonist administration.

  Archives of gynecology and obstetrics 20100601

• Sustained gonadotropin-releasing hormone stimulation mobilizes the cAMP/PKA pathway to induce nitric oxide synthase type 1 expression in rat pituitary cells in vitro and in vivo at proestrus.

  Biology of reproduction 20100601

• The effect of detergents and lipids on the properties of the outer-membrane protein OmcA from Shewanella oneidensis.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100601

• Three new dioxopiperazine metabolites from a marine-derived fungus Aspergillus fumigatus Fres.

  Natural product research 20100601

• Hydrothermal synthesis of platinum-group-metal nanoparticles by using HEPES as a reductant and stabilizer.

  Chemistry, an Asian journal 20100601

• Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin.

  PLoS pathogens 20100601

• Drug treatment of obsessive-compulsive disorder.

  Dialogues in clinical neuroscience 20100601

• Triptorelin and sex offenders. Limited clinical data.

  Prescrire international 20100601

• Degarelix. More rapid medical castration, nothing more.

  Prescrire international 20100601

• Synthesis and anthelmintic activity of some novel 2-substituted-4,5-diphenyl imidazoles.

  Acta pharmaceutica (Zagreb, Croatia) 20100601

• catena-Poly[[diaqua-cadmium(II)]bis-(μ-2,2-dimethyl-butane-dioato-κO,O':O'',O''')[diaqua-cadmium(II)]-μ-1,4-bis-(3-pyridylmeth-yl)piperazine-κN:N].

  Acta crystallographica. Section E, Structure reports online 20100601

• 5-(4-Methyl-piperazin-1-yl)-2-nitro-aniline.

  Acta crystallographica. Section E, Structure reports online 20100601

• tert-Butyl 4-(2-diazo-acet-yl)piperazine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20100601

• The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists.

  Journal of medicinal chemistry 20100527

• Design of new potent and selective secretory phospholipase A(2) inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives.

  Bioorganic & medicinal chemistry 20100515

• Synthesis and biological activity of some novel trifluoromethyl-substituted 1,2,4-triazole and bis(1,2,4-triazole) Mannich bases containing piperazine rings.

  Journal of agricultural and food chemistry 20100512

• Quantitative analysis of cell surface membrane proteins using membrane-impermeable chemical probe coupled with 18O labeling.

  Journal of proteome research 20100507

• Annulated diketopiperazines from dipeptides or Schöllkopf reagents via tandem cyclization-intramolecular N-arylation.

  Organic letters 20100507

• Capillary electrophoresis determination of antihistamines in serum and pharmaceuticals.

  Analytica chimica acta 20100507

• Phosphatase and tensin homolog gene inhibits the effect induced by gonadotropin-releasing hormone subtypes in human endometrial carcinoma cells.

  Chinese medical journal 20100505

• Role of minor determinants of amoxicillin in the diagnosis of immediate allergic reactions to amoxicillin.

  Allergy 20100501

• A novel substituted piperazine, CM156, attenuates the stimulant and toxic effects of cocaine in mice.

  The Journal of pharmacology and experimental therapeutics 20100501

• Hydride transfer reactions via ion-neutral complex: fragmentation of protonated N-benzylpiperidines and protonated N-benzylpiperazines in mass spectrometry.

  Journal of mass spectrometry : JMS 20100501

• Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization.

  Bioorganic & medicinal chemistry letters 20100501

• Involvement and specificity of Shewanella oneidensis outer membrane cytochromes in the reduction of soluble and solid-phase terminal electron acceptors.

  FEMS microbiology letters 20100501

• Discovery of novel leukotriene A4 hydrolase inhibitors based on piperidine and piperazine scaffolds.

  Bioorganic & medicinal chemistry letters 20100501

• Anti-microtubule 'plinabulin' chemical probe KPU-244-B3 labeled both alpha- and beta-tubulin.

  Bioorganic & medicinal chemistry 20100501

• Enantioseparation of amino acids and alpha-hydroxy acids on ligand-exchange continuous beds by capillary electrochromatography.

  Electrophoresis 20100501

• Snapping wrist caused by synovial giant cell tumour and anomalous lumbrical muscle: a case report.

  The Journal of hand surgery, European volume 20100501

• Novoamauromine and ent-Cycloechinulin: two new diketopiperazine derivatives from Aspergillus novofumigatus.

  Chemical & pharmaceutical bulletin 20100501

• Comparative analysis of six months formulation of LHRH analogues for prostate cancer treatment.

  Archivos espanoles de urologia 20100501

• 2-Methyl-piperazinediium tetra-chlorido-zincate(II).

  Acta crystallographica. Section E, Structure reports online 20100501

• Dimethyl cis-4-hydroxy-methyl-piperidine-2,6-dicarboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20100501

• Piperazine-1,4-diium bis-(3,5-dicarboxy-benzoate).

  Acta crystallographica. Section E, Structure reports online 20100501

• Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine.

  The Journal of biological chemistry 20100416

• Synthesis and biological evaluation of piperazinyl heterocyclic antagonists of the gonadotropin releasing hormone (GnRH) receptor.

  Bioorganic & medicinal chemistry letters 20100415

• A flow-based synthesis of imatinib: the API of Gleevec.

  Chemical communications (Cambridge, England) 20100414

• Responsive, di-metallic lanthanide complexes of a piperazine-bridged bis-macrocyclic ligand: modulation of visible luminescence and proton relaxivity.

  Dalton transactions (Cambridge, England : 2003) 20100414

• N-heterocycle construction via cyclic sulfamidates. Applications in synthesis.

  Organic & biomolecular chemistry 20100407

• A unique nickel system having versatile catalytic activity of biological significance.

  Inorganic chemistry 20100405

• Piperazine bridged resorcinarene cages.

  Organic letters 20100402

• Synthesis of hexa- and pentasubstituted diketopiperazines from sterically hindered amino acids.

  Organic letters 20100402

• Surgical diagnosis and management of intestinal obstruction due to Ascaris lumbricoides.

  Surgical infections 20100401

• LC-MS/MS screening method for designer amphetamines, tryptamines, and piperazines in serum.

  Analytical and bioanalytical chemistry 20100401

• Protective effect of a gonadotropin-releasing hormone analogue on chemotherapeutic agent-induced ovarian gonadotoxicity: a mouse model.

  European journal of obstetrics, gynecology, and reproductive biology 20100401

• Cumulative live birth rates after GnRH-agonist triggering of final oocyte maturation in patients at risk of OHSS: a prospective, clinical cohort study.

  European journal of obstetrics, gynecology, and reproductive biology 20100401

• Preoperative therapy with trastuzumab and oral vinorelbine (+/- endocrine therapy) in patients with HER2-positive breast cancer.

  Breast (Edinburgh, Scotland) 20100401

• Quantitative analysis of penicillins in porcine tissues, milk and animal feed using derivatisation with piperidine and stable isotope dilution liquid chromatography tandem mass spectrometry.

  Analytical and bioanalytical chemistry 20100401

• Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via GPCR Galphai proteins and matrix metalloproteinase-9.

  Glycoconjugate journal 20100401

• Synthesis and biological evaluation of 3-aminopyrrolidine derivatives as CC chemokine receptor 2 antagonists.

  Bioorganic & medicinal chemistry letters 20100401

• Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi.

  Bioorganic & medicinal chemistry 20100401

• (1R,2R,3S,6aS,7R,8R,9S,12aS)-1,2,3,7,8,9-Hexahydroxy-perhydro-dipyrido[1,2-a:1',2'-d]pyrazine-6,12-dione.

  Acta crystallographica. Section E, Structure reports online 20100401

• Total synthesis of (+)-chaetocin and its analogues: their histone methyltransferase G9a inhibitory activity.

  Journal of the American Chemical Society 20100331

• New discrete and polymeric supramolecular architectures derived from dinuclear Co(II), Ni(II) and Cu(II) complexes of aryl-linked bis-beta-diketonato ligands and nitrogen bases: synthetic, structural and high pressure studies.

  Dalton transactions (Cambridge, England : 2003) 20100321

• Evaluation of alkanolamine solutions for carbon dioxide removal in cross-flow rotating packed beds.

  Journal of hazardous materials 20100315

• Kinetics of removal of carbon dioxide by aqueous solutions of N,N-diethylethanolamine and piperazine.

  Environmental science & technology 20100315

• Synthetic mimetics of protein secondary structure domains.

  Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20100313

• Piperazinyl glutamate pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation.

  Journal of medicinal chemistry 20100311

• Computational insights into the interactions between DNA and siRNA with 'rigid' and 'flexible' triazine dendrimers.

  Biomacromolecules 20100308

• Pharmacophore mapping and electronic feature analysis for a series of nitroaromatic compounds with antitubercular activity.

  Journal of computational chemistry 20100301

• A comparative study of the efficacy of piperazine and Carica papaya for the control of helminth parasites in village chickens in Zambia.

  Tropical animal health and production 20100301

• Triptorelin improves intestinal symptoms among patients with colorectal endometriosis.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20100301

• Synthesis of tropolone derivatives and evaluation of their in vitro neuroprotective activity.

  European journal of medicinal chemistry 20100301

• Molecular modeling studies on the human neuropeptide S receptor and its antagonists.

  ChemMedChem 20100301

• Arylpiperazine-containing pyrrole 3-carboxamide derivatives targeting serotonin 5-HT(2A), 5-HT(2C), and the serotonin transporter as a potential antidepressant.

  Bioorganic & medicinal chemistry letters 20100301

• Bacillus thuringiensis Cry5B protein is highly efficacious as a single-dose therapy against an intestinal roundworm infection in mice.

  PLoS neglected tropical diseases 20100301

• Inhibitors of human histone deacetylase: synthesis and enzyme assay of hydroxamates with piperazine linker.

  Archiv der Pharmazie 20100301

• Cyclohexene, diketopiperazine, lactone and phenol derivatives from the sea fan-derived fungi Nigrospora sp. PSU-F11 and PSU-F12.

  Archives of pharmacal research 20100301

• Neuropharmacology of vestibular system disorders.

  Current neuropharmacology 20100301

• Tris(piperazinediium) phosphatododeca-molybo(V,VI)phosphate.

  Acta crystallographica. Section E, Structure reports online 20100301

• Poly[[aqua-[μ-1,4-bis-(3-pyridylmeth-yl)piperazine-κN:N'](μ-isophthalato-κO:O)copper(II)].

  Acta crystallographica. Section E, Structure reports online 20100301

• 3-Chloro-6-{4-[3-(trifluoro-meth-yl)phen-yl]piperazin-1-yl}pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100301

• 4-(3-Carb-oxy-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-7-quinol-yl)-1-methyl-piper-azin-ium picrate.

  Acta crystallographica. Section E, Structure reports online 20100301

• 3-Chloro-6-{4-[3-(4-chloro-phen-oxy)prop-yl]piperazin-1-yl}pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100301

• De novo design of a picomolar nonbasic 5-HT(1B) receptor antagonist.

  Journal of medicinal chemistry 20100225

• Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases.

  Journal of medicinal chemistry 20100225

• Triptorelin embonate (6-month formulation).

  Drugs 20100212

• Development of (S)-N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and its analogue as a D3 receptor preferring agonist: potent in vivo activity in Parkinson's disease animal models.

  Journal of medicinal chemistry 20100211

• Benzimidazole derivatives as new serotonin 5-HT6 receptor antagonists. Molecular mechanisms of receptor inactivation.

  Journal of medicinal chemistry 20100211

• Capillary electrophoresis analysis of the degradation of the aspartyl tripeptide Phe-Asp-GlyOH at pH 2.0 and 7.4 under forced conditions.

  Journal of pharmaceutical and biomedical analysis 20100205

• A novel DNA intercalator, butylamino-pyrimido[4',5':4,5]selenolo(2,3-b)quinoline, induces cell cycle arrest and apoptosis in leukemic cells.

  Investigational new drugs 20100201

• Hypokalemic paralysis following severe vomiting in a child with intestinal obstruction due to round worms.

  Journal of tropical pediatrics 20100201

• Structural analysis and the effect of cyclo(His-Pro) dipeptide on neurotoxins--a dynamics and density functional theory study.

  Journal of molecular modeling 20100201

• Dual role of hydrophobic racemic thioesters of alpha-amino acids in the generation of isotactic peptides and co-peptides in water; implications for the origin of homochirality.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20100201

• Efficient microwave combinatorial synthesis of novel indolic arylpiperazine derivatives as serotoninergic ligands.

  European journal of medicinal chemistry 20100201

• Piperazinyl pyrimidine derivatives as potent gamma-secretase modulators.

  Bioorganic & medicinal chemistry letters 20100201

• Molecular modeling study of 4-phenylpiperazine and 4-phenyl-1,2,3,6-tetrahydropyridine derivatives: a new step towards the design of high-affinity 5-HT1A ligands.

  Bioorganic & medicinal chemistry letters 20100201

• Syntheses and antibacterial activity studies of new oxazolidinones from nitroso Diels-Alder chemistry.

  Bioorganic & medicinal chemistry letters 20100201

• Design and synthesis of piperazine-indole p38 alpha MAP kinase inhibitors with improved pharmacokinetic profiles.

  Bioorganic & medicinal chemistry letters 20100201

• Synthesis and biological activity of some 1,3-dihydro-2H-3-benzazepin-2-ones with a piperazine moiety as bradycardic agents.

  Archiv der Pharmazie 20100201

• Angina in Women without Obstructive Coronary Artery Disease.

  Current cardiology reviews 20100201

• 4-(Methyl-sulfon-yl)piperazin-1-ium chloride.

  Acta crystallographica. Section E, Structure reports online 20100201

• Imatinibium dipicrate.

  Acta crystallographica. Section E, Structure reports online 20100201

• (3R,8aS)-3-Ethyl-perhydro-pyrrolo[1,2-a]pyrazine-1,4-dione.

  Acta crystallographica. Section E, Structure reports online 20100201

• Modular synthesis and in vitro and in vivo antimalarial assessment of C-10 pyrrole mannich base derivatives of artemisinin.

  Journal of medicinal chemistry 20100128

• Reversal agent and linker variants of reversed chloroquines: activities against Plasmodium falciparum.

  Journal of medicinal chemistry 20100128

• Dramatic increase of selectivity for heavy lanthanide(III) cations by tuning the flexibility of polydentate chelators.

  Inorganic chemistry 20100118

• Novel organic proteasome inhibitors identified by virtual and in vitro screening.

  Journal of medicinal chemistry 20100114

• Theoretical and experimental studies of the isomeric protonation in solution for a prototype aliphatic ring containing two nitrogens.

  The journal of physical chemistry. B 20100114

• A randomized, controlled clinical trial comparing the effects of aromatase inhibitor (letrozole) and gonadotropin-releasing hormone agonist (triptorelin) on uterine leiomyoma volume and hormonal status.

  Fertility and sterility 20100101

• Cationic phosphorodiamidate morpholino oligomers efficiently prevent growth of Escherichia coli in vitro and in vivo.

  The Journal of antimicrobial chemotherapy 20100101

• Complete experimental and theoretical proton and carbon nuclear magnetic resonance spectral assignments, molecular structure and conformational study of 1-cyclohexylpiperazine and 1-(4-pyridyl)piperazine.

  Magnetic resonance in chemistry : MRC 20100101

• Anticancer activity of a new gonadotropin releasing hormone analogue.

  Biopolymers 20100101

• Antiplasmodial activity of piperazine sulfonamides.

  Bioorganic & medicinal chemistry letters 20100101

• Efficacy of gonadotropin-releasing hormone agonist and an extended-interval dosing regimen in the treatment of patients with adenomyosis and endometriosis.

  Gynecologic and obstetric investigation 20100101

• Role of outer-membrane cytochromes MtrC and OmcA in the biomineralization of ferrihydrite by Shewanella oneidensis MR-1.

  Geobiology 20100101

• Prediction of partial molar volumes of amino acids and small peptides: counting atoms versus topological indices.

  Journal of chemical information and modeling 20100101

• Phylogenomics reveals subfamilies of fungal nonribosomal peptide synthetases and their evolutionary relationships.

  BMC evolutionary biology 20100101

• Growth inhibition of androgen-responsive prostate cancer cells with brefeldin A targeting cell cycle and androgen receptor.

  Journal of biomedical science 20100101

• Echinocandin treatment of pneumocystis pneumonia in rodent models depletes cysts leaving trophic burdens that cannot transmit the infection.

  PloS one 20100101

• Dynamics of muscle fibre growth during postnatal mouse development.

  BMC developmental biology 20100101

• Synthesis and anticonvulsant activity of new kojic acid derivatives.

  Arzneimittel-Forschung 20100101

• Stereochemical basis for a unified structure activity theory of aromatic and heterocyclic rings in selected opioids and opioid peptides.

  Perspectives in medicinal chemistry 20100101

• Identification of a tsetse fly salivary protein with dual inhibitory action on human platelet aggregation.

  PloS one 20100101

• Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents.

  Pharmacological reports : PR 20100101

• Use of human cancer cell lines mitochondria to explore the mechanisms of BH3 peptides and ABT-737-induced mitochondrial membrane permeabilization.

  PloS one 20100101

• Effect of treatment with cyproterone acetate on uterine bleeding at the beginning of GnRH analogue therapy in girls with idiopathic central precocious puberty.

  Hormone research in paediatrics 20100101

• Cyclodepsipeptides from marine sponges: natural agents for drug research.

  Marine drugs 20100101

• Development of a cell-based high-throughput assay to screen for inhibitors of organic anion transporting polypeptides 1B1 and 1B3.

  Current chemical genomics 20100101

• Toxicology and drug delivery by cucurbit[n]uril type molecular containers.

  PloS one 20100101

• Marine drugs from sponge-microbe association--a review.

  Marine drugs 20100101

• Genome-wide expression links the electron transfer pathway of Shewanella oneidensis to chemotaxis.

  BMC genomics 20100101

• The Waddlia genome: a window into chlamydial biology.

  PloS one 20100101

• Characterisation of the binding properties of Bacillus thuringiensis 18 toxin on leukaemic cells.

  Journal of experimental & clinical cancer research : CR 20100101

• Synthesis and characterization of ester-based prodrugs of glucagon-like peptide 1.

  Biopolymers 20100101

• Recurrent endometrial stromal sarcoma: treatment with a progestin and gonadotropin releasing hormone agonist.

  Sarcoma 20100101

• Gonadotropin-releasing hormone type II antagonist induces apoptosis in MCF-7 and triple-negative MDA-MB-231 human breast cancer cells in vitro and in vivo.

  Breast cancer research : BCR 20100101

• [Electrophysiological diagnosis of severe carpal tunnel syndrome in patients on maintenance hemodialysis with created arterio-venous fistula and concomitant polyneuropathy].

  Przeglad lekarski 20100101

• Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system.

  Journal of nanobiotechnology 20100101

• An experimental investigation of the evolution of chirality in a potential dynamic peptide system: N-terminal epimerization and degradation into diketopiperazine.

  Astrobiology 20100101

• Administration of single-dose GnRH agonist in the luteal phase in ICSI cycles: a meta-analysis.

  Reproductive biology and endocrinology : RB&E 20100101

• Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping.

  Molecular pain 20100101

• Recent advances in the management of chronic stable angina II. Anti-ischemic therapy, options for refractory angina, risk factor reduction, and revascularization.

  Vascular health and risk management 20100101

• Two-stage reconstruction for flexor tendon injuries in zone II using a silicone rod and pedicled sublimis tendon graft.

  Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India 20100101

• Aggressive angiomyxoma of the vulva: case report and literature review.

  The Journal of international medical research 20100101

• Etiology and antibacterial susceptibility pattern of community-acquired bacterial ocular infections in a tertiary eye care hospital in south India.

  Indian journal of ophthalmology 20100101

• Materials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspects.

  International journal of molecular sciences 20100101

• Optimization-based metabolic control analysis.

  Biotechnology progress 20100101

• Enabling unbalanced fermentations by using engineered electrode-interfaced bacteria.

  mBio 20100101

• [Biologically active metabolites of the marine actinobacteria].

  Bioorganicheskaia khimiia 20100101

• Identification of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) as a binding protein for a 68-kDa Bacillus thuringiensis parasporal protein cytotoxic against leukaemic cells.

  Journal of biomedical science 20100101

• Crystal structure and complexation and fluorescence behaviors of 1,4-bis (9-anthracenylmethyl) piperazine.

  Journal of oleo science 20100101

• An empirical strategy for characterizing bacterial proteomes across species in the absence of genomic sequences.

  PloS one 20100101

• Immense essence of excellence: marine microbial bioactive compounds.

  Marine drugs 20100101

• Marine antitumor drugs: status, shortfalls and strategies.

  Marine drugs 20100101

• Functional cooperation of of IL-1β and RGS4 in the brachial plexus avulsion mediated brain reorganization.

  Journal of brachial plexus and peripheral nerve injury 20100101

• Metabotropic glutamate receptors: potential drug targets for psychiatric disorders.

  The open medicinal chemistry journal 20100101

• Preliminary observations of muscle fibre cross sectional area of flexor digitorum brevis in cadaver feet with and without claw toes.

  Journal of foot and ankle research 20100101

• Control of nematode parasites with agents acting on neuro-musculature systems: lessons for neuropeptide ligand discovery.

  Advances in experimental medicine and biology 20100101

• Modified natural cycle for in vitro fertilization and embryo transfer in normal ovarian responders.

  The Journal of international medical research 20100101

• In vitro Effects of Albendazole on Raillietina echinobothrida, the Cestode of Chicken, Gallus domesticus.

  Journal of young pharmacists : JYP 20100101

• Bioactive dehydrotyrosyl and dehydrodopyl compounds of marine origin.

  Marine drugs 20100101

• Leuprolide acetate 1-month depot for central precocious puberty: hormonal suppression and recovery.

  International journal of pediatric endocrinology 20100101

• 7-(4-Methoxy-phen-yl)-5-methyl-9-phenyl-7H-pyrrolo[2',3':4,5]pyrimido[1,6-d]tetrazole.

  Acta crystallographica. Section E, Structure reports online 20100101

• 3-Chloro-6-[4-(2-pyrid-yl)piperazin-1-yl]pyridazine.

  Acta crystallographica. Section E, Structure reports online 20100101

• Acute gastroenteritis: from guidelines to real life.

  Clinical and experimental gastroenterology 20100101

• Synthesis and Antibacterial and Antifungal Studies of Novel Nitrogen Containing Heterocycles from 5-Ethylpyridin-2-ethanol.

  Indian journal of pharmaceutical sciences 20100101

• Phytochemical and pharmacological review of Lagenaria sicereria.

  Journal of Ayurveda and integrative medicine 20100101

• Structural modifications of quinoline-based antimalarial agents: Recent developments.

  Journal of pharmacy & bioallied sciences 20100101

• Evaluation of Anthelmintic Activities of Aerial Parts of Cynodon dactylon Pers.

  Ancient science of life 20100101

• Al(OTf)(3)-mediated epoxide ring-opening reactions: toward piperazine-derived physiologically active products.

  The Journal of organic chemistry 20091218

• Nonpeptide urotensin-II receptor antagonists: a new ligand class based on piperazino-phthalimide and piperazino-isoindolinone subunits.

  Journal of medicinal chemistry 20091210

• Further studies on arylpiperazinyl alkyl pyridazinones: discovery of an exceptionally potent, orally active, antinociceptive agent in thermally induced pain.

  Journal of medicinal chemistry 20091210

• Evidence of diketopiperazine and oxazolone structures for HA b2+ ion.

  Journal of the American Chemical Society 20091209

• Testosterone partially ameliorates metabolic profile and erectile responsiveness to PDE5 inhibitors in an animal model of male metabolic syndrome.

  The journal of sexual medicine 20091201

• Synthesis and pharmacological evaluation of SNC80 analogues with a bridged piperazine ring.

  ChemMedChem 20091201

• Discovery and pharmacological characterization of aryl piperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists.

  Bioorganic & medicinal chemistry letters 20091201

• Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands.

  Bioorganic & medicinal chemistry letters 20091201

• The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists.

  ChemMedChem 20091201

• Abarelix and other gonadotrophin-releasing hormone antagonists in prostate cancer.

  BJU international 20091201

• [Summary of the ICOH 2009 Conference - Cape Town, South Africa].

  Harefuah 20091201

• Paradoxical exacerbation of chronic urticaria by H1-antihistamines and montelukast.

  European annals of allergy and clinical immunology 20091201

• Apoptosis of human Burkitt's lymphoma cells induced by 2-N,N-diethylaminocarbonyloxymethyl-1-diphenylmethyl-4-(3,4,5-trimethoxybenzoyl) piperazine hydrochloride (PMS-1077).

  Archives of pharmacal research 20091201

• [Increased risk of early pregnancy loss and lower live birth rate with GNRH antagonist vs. long GNRH agonist protocol in PCOS women undergoing controlled ovarian hyperstimulation].

  La Tunisie medicale 20091201

• catena-Poly[[diaqua-zinc(II)]-μ-piper-azine-1,4-diacetato-κN,O:N,O].

  Acta crystallographica. Section E, Structure reports online 20091201

• Poly[1,4-bis-(4-pyridylmeth-yl)piperazine-diium [[tetra-aqua-cobaltate(II)]-μ-pyromellitato-κO:O] dihydrate].

  Acta crystallographica. Section E, Structure reports online 20091201

• 4,4'-[Piperazine-1,4-diylbis(propyl-ene-nitrilo-methyl-idyne)]diphenol.

  Acta crystallographica. Section E, Structure reports online 20091201

• 1,4-Bis{3-[4-(dimethyl-amino)benzyl-ideneamino]prop-yl}piperazine.

  Acta crystallographica. Section E, Structure reports online 20091201

• Redetermination of 2-[4-(2-hydroxy-ethyl)piperazin-1-ium-1-yl]ethanesul-fonate at 100 K.

  Acta crystallographica. Section E, Structure reports online 20091201

• [2-(4-Methyl-piperazin-1-ylmeth-yl)phen-yl]diphenyl-phosphane.

  Acta crystallographica. Section E, Structure reports online 20091201

• Syntheses, crystal structures, thermal stabilities and luminescence of two new zinc phosphonates.

  Dalton transactions (Cambridge, England : 2003) 20091121

• Synthesis and evaluation of a novel class of G-quadruplex-stabilizing small molecules based on the 1,3-phenylene-bis(piperazinyl benzimidazole) system.

  Biochemistry 20091117

• Cyclic RGD-peptidomimetics containing bifunctional diketopiperazine scaffolds as new potent integrin ligands.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20091116

• Novel, potent, and selective quinoxaline-based 5-HT(3) receptor ligands. 1. Further structure-activity relationships and pharmacological characterization.

  Journal of medicinal chemistry 20091112

• Novel piperazine derivative PMS1339 exhibits tri-functional properties and cognitive improvement in mice.

  The international journal of neuropsychopharmacology 20091101

• The use of driving impairing medicines: a European survey.

  European journal of clinical pharmacology 20091101

• Fragmentation of doubly-protonated Pro-His-Xaa tripeptides: formation of b(2)(2+) ions.

  Journal of the American Society for Mass Spectrometry 20091101

• [Myocardial infarction and ovarian stimulation: case report].

  Annales de cardiologie et d'angeiologie 20091101

• Piperazine-1,4-diium bis-[tetra-chlorido-aurate(III)] dihydrate.

  Acta crystallographica. Section E, Structure reports online 20091101

• 1,1,4,4-Tetra-methyl-piperazinediium dibromide.

  Acta crystallographica. Section E, Structure reports online 20091101

• Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family.

  Journal of medicinal chemistry 20091008

• Peptide conformer acidity analysis of protein flexibility monitored by hydrogen exchange.

  Biochemistry 20091006

• The GnRH analogue triptorelin confers ovarian radio-protection to adult female rats.

  Mutation research 20091002

• Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity.

  European journal of medicinal chemistry 20091001

• Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse.

  Human molecular genetics 20091001

• Dissociation of protonated peptides containing adjacent arginines.

  Journal of biomolecular structure & dynamics 20091001

• A cadaver model that investigates irreducible metacarpophalangeal joint dislocation.

  The Journal of hand surgery 20091001

• Structural determination of sildenafil and its analogues in dietary supplements by fast-atom bombardment collision-induced dissociation tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20091001

• Degarelix.

  Drugs 20091001

• GnRH agonist versus recombinant HCG in an oocyte donation programme: a randomized, prospective, controlled, assessor-blind study.

  Reproductive biomedicine online 20091001

• [Stanozolol activates the cross-talk of estrogen receptor alpha-insulin-like growth factor-1 receptor-extracellular-signal regulated kinase 1/2 in the growth plate chondrocytes of estrogen-inhibited adolescent rats in vitro].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20091001

• Ciprofloxacin in hospital effluent: degradation by ozone and photoprocesses.

  Journal of hazardous materials 20090930

• Stereocontrolled and versatile total synthesis of bispyrrolidinoindoline diketopiperazine alkaloids: structural revision of the fungal isolate (+)-asperdimin.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090928

• Construction of drug screening cell model and application to new compounds inhibiting FITC-fibrinogen binding to CHO cells expressing human alphaIIbbeta3.

  European journal of pharmacology 20090915

• Structural characterization of sulfoaildenafil, an analog of sildenafil.

  Journal of pharmaceutical and biomedical analysis 20090908

• Distinct structural features of cyclothiazide are responsible for effects on peak current amplitude and desensitization kinetics at iGluR2.

  Journal of molecular biology 20090904

• Naseseazines A and B: a new dimeric diketopiperazine framework from a marine-derived actinomycete, Streptomyces sp.

  Organic letters 20090903

• Effect of the pH grade of silicates on chemical stability of coground amorphous quinapril hydrochloride and its stabilization using pH-modifiers.

  Journal of pharmaceutical sciences 20090901

• Health-related quality of life following surgical menopause and following gonadotrophin-releasing hormone analogue-induced pseudomenopause.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090901

• Quantitative structure activity relationship studies of piperazinyl phenylalanine derivatives as VLA-4/VCAM-1 inhibitors.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20090901

• Discovery of a small molecule inhibitor through interference with the gp120-CD4 interaction.

  Bioorganic & medicinal chemistry letters 20090901

• Novel CXCR3 antagonists with a piperazinyl-piperidine core.

  Bioorganic & medicinal chemistry letters 20090901

• Inhibitors of HIV-1 attachment. Part 4: A study of the effect of piperazine substitution patterns on antiviral potency in the context of indole-based derivatives.

  Bioorganic & medicinal chemistry letters 20090901

• Cerebrosides of the halotolerant fungus Alternaria raphani isolated from a sea salt field.

  Journal of natural products 20090901

• Beneficial effect of luteal-phase gonadotropin-releasing hormone agonist administration on implantation rate after intracytoplasmic sperm injection.

  Taiwanese journal of obstetrics & gynecology 20090901

• 1-Cyclohexylpiperazine and 3,3-dimethylpiperidine derivatives as sigma-1 (sigma1) and sigma-2 (sigma2) receptor ligands: a review.

  Central nervous system agents in medicinal chemistry 20090901

• Bis(ethyl-enediamine-κN,N')(nitrato-κO,O')cobalt(III) hydroxide nitrate.

  Acta crystallographica. Section E, Structure reports online 20090901

• Brevianamide J, a new indole alkaloid dimer from fungus Aspergillus versicolor.

  Organic letters 20090820

• Solvatochromic fluorescence of piperazine-modified bipyridazines for an organic solvent-sensitive film.

  Langmuir : the ACS journal of surfaces and colloids 20090818

• Sulfonamides with the N-alkyl-N'-dialkylguanidine moiety as 5-HT7 receptor ligands.

  Bioorganic & medicinal chemistry letters 20090815

• Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I-XIV.

  Bioorganic & medicinal chemistry 20090815

• Stability of triptorelin in the presence of dermis and epidermis.

  International journal of pharmaceutics 20090813

• LYG-202, a new flavonoid with a piperazine substitution, shows antitumor effects in vivo and in vitro.

  Biochemical and biophysical research communications 20090807

• Expedite protocol for construction of chiral regioselectively N-protected monosubstituted piperazine, 1,4-diazepane, and 1,4-diazocane building blocks.

  The Journal of organic chemistry 20090807

• Temperature and chemical environment effects on the aggregation extent of water soluble perylene dye into vinyl alcohol-containing polymers.

  Physical chemistry chemical physics : PCCP 20090807

• Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.

  ChemMedChem 20090803

• Synthesis and evaluation of 1-(1-(Benzo[b]thiophen-2-yl)cyclohexyl)piperidine (BTCP) analogues as inhibitors of trypanothione reductase.

  ChemMedChem 20090803

• Sting-ray injuries to the hand: case report, literature review and a suggested algorithm for management.

  Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20090801

• Synthesis and antibacterial activity of novel 5-(4-methyl-1H-1,2,3-triazole) methyl oxazolidinones.

  European journal of medicinal chemistry 20090801

• Disposition and metabolism of radiolabeled casopitant in humans.

  Drug metabolism and disposition: the biological fate of chemicals 20090801

• Fragmentation of deprotonated cyclic dipeptides by electrospray ionization mass spectrometry.

  Journal of mass spectrometry : JMS 20090801

• Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801

• Synthesis of dimeric quinazolin-2-one, 1,4-benzodiazepin-2-one, and isoalloxazine compounds as inhibitors of amyloid peptides association.

  Archiv der Pharmazie 20090801

• Identification, structure-activity relationships and molecular modeling of potent triamine and piperazine opioid ligands.

  Bioorganic & medicinal chemistry 20090801

• 7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents.

  Bioorganic & medicinal chemistry 20090801

• Diketopiperazine alkaloids from a deep ocean sediment derived fungus Penicillium sp.

  Chemical & pharmaceutical bulletin 20090801

• Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics.

  PLoS neglected tropical diseases 20090801

• First live birth following IVF-embryo transfer and use of GnRHa alone for ovarian stimulation.

  Reproductive biomedicine online 20090801

• Reduced exposure of imatinib after coadministration with acetaminophen in mice.

  Indian journal of pharmacology 20090801

• Poly[[bis-[μ-1,4-bis-(3-pyridylmeth-yl)piperazine-κN:N']dichlorido-cadmium(II)] tetra-hydrate].

  Acta crystallographica. Section E, Structure reports online 20090801

• N,N,2,5,7-Penta-phenyl-2,5,7-triaza-bicyclo-[2.2.1]heptane-3,6-diamine.

  Acta crystallographica. Section E, Structure reports online 20090801

• 1,4-Bis(4-pyridylmeth-yl)piperazin-1-ium perchlorate fumaric acid hemisolvate.

  Acta crystallographica. Section E, Structure reports online 20090801

• Piperidinium, piperazinium and morpholinium ionic liquid crystals.

  The journal of physical chemistry. B 20090716

• 'Click' D(1) receptor agonists with a 5-HT(1A) receptor pharmacophore producing D(2) receptor activity.

  Bioorganic & medicinal chemistry 20090715

• Retention of ionisable compounds on high-performance liquid chromatography XIX. pH variation in mobile phases containing formic acid, piperazine and tris as buffering systems and methanol as organic modifier.

  Journal of chromatography. A 20090710

• Free-radical-induced oxidative and reductive degradation of fluoroquinolone pharmaceuticals: kinetic studies and degradation mechanism.

  The journal of physical chemistry. A 20090709

• Identification of an imidazoline binding protein: creatine kinase and an imidazoline-2 binding site.

  Brain research 20090707

• Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities.

  European journal of medicinal chemistry 20090701

• Immunolocalization of GQ1b and related gangliosides in human extraocular neuromuscular junctions and muscle spindles.

  Investigative ophthalmology & visual science 20090701

• Interaction of organotin with piperazine derived self-assembled cylindrical bisdithiocarbamates: spectral and thermal investigations.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090701

• Photo-degradation of the antimicrobial ciprofloxacin at high pH: identification and biodegradability assessment of the primary by-products.

  Chemosphere 20090701

• Levofloxacin ozonation in water: rate determining process parameters and reaction pathway elucidation.

  Chemosphere 20090701

• Conformationally constrained analogs of N-substituted piperazinylquinolones: synthesis and antibacterial activity of N-(2,3-dihydro-4-hydroxyimino-4H-1-benzopyran-3-yl)-piperazinylquinolones.

  Archiv der Pharmazie 20090701

• Metabolic interactions with piperazine-based 'party pill' drugs.

  The Journal of pharmacy and pharmacology 20090701

• Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening.

  PLoS neglected tropical diseases 20090701

• Effects of ranolazine, a novel anti-anginal drug, on ion currents and membrane potential in pituitary tumor GH(3) cells and NG108-15 neuronal cells.

  Journal of pharmacological sciences 20090701

• An updated review on the efficacy of adjuvant endocrine therapies in hormone receptor-positive early breast cancer.

  Current oncology (Toronto, Ont.) 20090701

• Evaluation of the extent of protein binding by means of NMR diffusion and relaxation experiments, and automated continuous ultrafiltration.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

• Triprotic acid-base microequilibria and pharmacokinetic sequelae of cetirizine.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628

• Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors.

  Bioorganic & medicinal chemistry letters 20090615

• New types of 3D organically templated Zn2+/Cd2+-Cu+ mixed metal sulfites.

  Inorganic chemistry 20090615

• Synthesis of proline-based diketopiperazine scaffolds.

  The Journal of organic chemistry 20090605

• Robust self-assembled monolayers of Ru(II) and Os(II) polypyridines on gold surfaces: exploring new potentials.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090602

• Synthesis of new piperazine derived Cu(II)/Zn(II) metal complexes, their DNA binding studies, electrochemistry and anti-microbial activity: validation for specific recognition of Zn(II) complex to DNA helix by interaction with thymine base.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090601

• Degradable poly(beta-amino ester) nanoparticles for cancer cytoplasmic drug delivery.

  Nanomedicine : nanotechnology, biology, and medicine 20090601

• Acaricidal properties of piperazine and its derivatives against house-dust and stored-food mites.

  Pest management science 20090601

• Influence of fluorocarbon flat-membrane hydrophobicity on carbon dioxide recovery.

  Chemosphere 20090601

• Investigation of various N-heterocyclic substituted piperazine versions of 5/7-{[2-(4-aryl-piperazin-1-yl)-ethyl]-propyl-amino}-5,6,7,8-tetrahydro-naphthalen-2-ol: effect on affinity and selectivity for dopamine D3 receptor.

  Bioorganic & medicinal chemistry 20090601

• Cyclodipeptide synthases are a family of tRNA-dependent peptide bond-forming enzymes.

  Nature chemical biology 20090601

• In vivo and in vitro effects of fluoroquinolones on lipopolysaccharide-induced pro-inflammatory cytokine production.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20090601

• 1-Chloro-2-(4-phenyl-piperazin-1-yl)ethanone.

  Acta crystallographica. Section E, Structure reports online 20090601

• Multimetallic arrays: symmetrical bi-, tri- and tetrametallic complexes based on the group 10 metals and the functionalisation of gold nanoparticles with nickel-phosphine surface units.

  Dalton transactions (Cambridge, England : 2003) 20090521

• Synthesis and evaluation of piperazine and homopiperazine analogues of JS-K, an anti-cancer lead compound.

  Bioorganic & medicinal chemistry letters 20090515

• Influence of superheated water on the hydrogen bonding and crystallography of piperazine-based (Co)polyamides.

  Langmuir : the ACS journal of surfaces and colloids 20090505

• Leiomyoma pseudocapsule after pre-surgical treatment with gonadotropin-releasing hormone agonists: relationship between clinical features and immunohistochemical changes.

  European journal of obstetrics, gynecology, and reproductive biology 20090501

• Characterization of imatinib metabolites in rat and human liver microsomes: differentiation of hydroxylation from N-oxidation by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20090501

• Metacarpophalangeal joint dislocation.

  The Journal of the American Academy of Orthopaedic Surgeons 20090501

• catena-Poly[[dichloridozinc(II)]-μ-1,4-bis-(3-pyridylmeth-yl)piperazine].

  Acta crystallographica. Section E, Structure reports online 20090501

• Piperazinediium dioxamate.

  Acta crystallographica. Section E, Structure reports online 20090501

• Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.

  Chemistry & biology 20090424

• Selective anion binding in water with use of a zinc(II) dipicolylamino functionalized diketopiperazine scaffold.

  The Journal of organic chemistry 20090417

• Non-imidazole histamine H3 ligands, part IV: SAR of 1-[2-thiazol-5-yl-(2-aminoethyl)]-4-n-propylpiperazine derivatives.

  European journal of medicinal chemistry 20090401

• Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity, part 1.

  European journal of medicinal chemistry 20090401

• An evaluation of the critical parameters for abiotic peptide synthesis in submarine hydrothermal systems.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090401

• What is the structure of b(2) ions generated from doubly protonated tryptic peptides?

  Journal of the American Society for Mass Spectrometry 20090401

• RETRACTED: Treatment of nonparaphilic hypersexuality in men with a long-acting analog of gonadotropin-releasing hormone.

  The journal of sexual medicine 20090401

• Multiple H1-antihistamine-induced urticaria.

  The Journal of dermatology 20090401

• Fluoroquinolones reduce carrageenan-induced edema in rats and the involvement of the glucocorticoid receptor system.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20090401

• [Long GnRH agonist vs. GnRH antagonist protocol in randomized controlled trial in unselected patients--hormonal and cycle characteristics--pilot study].

  Ceska gynekologie 20090401

• [Pharmacophore model of integrin alphavbeta3 antagonists].

  Yao xue xue bao = Acta pharmaceutica Sinica 20090401

• Ghrelin receptor modulators and their therapeutic potential.

  Future medicinal chemistry 20090401

• Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.

  Chembiochem : a European journal of chemical biology 20090323

• Retention of ionisable compounds on high-performance liquid chromatography XVIII: pH variation in mobile phases containing formic acid, piperazine, tris, boric acid or carbonate as buffering systems and acetonitrile as organic modifier.

  Journal of chromatography. A 20090320

• Biochemical basis for differences in metabolism-dependent genotoxicity by two diazinylpiperazine-based 5-HT2C receptor agonists.

  Bioorganic & medicinal chemistry letters 20090315

• Efficient parallel synthesis of privileged benzopyranylpyrazoles via regioselective condensation of beta-keto aldehydes with hydrazines.

  Journal of combinatorial chemistry 20090309

• Coordination polymers with pyridine-2,4,6-tricarboxylic acid and alkaline-earth/lanthanide/transition metals: synthesis and X-ray structures.

  Dalton transactions (Cambridge, England : 2003) 20090307

• N-Substituted piperazinyl quinolones as potential cytotoxic agents: structure-activity relationships study.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090301

• Selective P2X(7) receptor antagonists for chronic inflammation and pain.

  Purinergic signalling 20090301

• Synthesis and antibacterial activity of nitroaryl thiadiazole-gatifloxacin hybrids.

  European journal of medicinal chemistry 20090301

• Synthesis and in vitro antiproliferative activity of novel 1-benzhydrylpiperazine derivatives against human cancer cell lines.

  European journal of medicinal chemistry 20090301

• Discovery of novel non-peptidic beta-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists.

  Bioorganic & medicinal chemistry letters 20090301

• 4-(4-Methoxy-phen-yl)piperazin-1-ium chloride.

  Acta crystallographica. Section E, Structure reports online 20090301

• 4-(4-Carboxy-benz-yl)-1-methyl-piperazin-1-ium picrate.

  Acta crystallographica. Section E, Structure reports online 20090301

• 4-Ethoxy-imino-N'-methoxy-pyrrolidin-1-ium-3-carboximidamidium dichloride.

  Acta crystallographica. Section E, Structure reports online 20090301

• Structure and dimensionality of coordination complexes correlated to piperazine conformation: from discrete [CuII2] and [CuII4] complexes to a micro1,3-N3- bridged [CuII2]n chain.

  Dalton transactions (Cambridge, England : 2003) 20090227

• Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential.

  Bioorganic & medicinal chemistry 20090215

• Estrogen suppression in premenopausal women following 8 weeks of treatment with exemestane and triptorelin versus triptorelin alone.

  Breast cancer research and treatment 20090201

• Triggering with human chorionic gonadotropin or a gonadotropin-releasing hormone agonist in gonadotropin-releasing hormone antagonist-treated oocyte donor cycles: findings of a large retrospective cohort study.

  Fertility and sterility 20090201

• Ovarian hyperstimulation syndrome following the sole administration of injectable gonadotropin-releasing hormone agonist (triptorelin) for the pituitary down-regulation and in vitro fertilization treatment: report of two cases.

  Archives of gynecology and obstetrics 20090201

• Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: antimicrobial, analgesic and antipyretic studies.

  European journal of medicinal chemistry 20090201

• 1,4-Diazepanes derived from (S)-serine--homopiperazines with improved sigma(1) (sigma) receptor affinity and selectivity.

  European journal of medicinal chemistry 20090201

• The influence of an ethylene spacer on the 5-HT(1A) and 5-HT(2A) receptor affinity of arylpiperazine derivatives of amides with N-acylated amino acids and 3-differently substituted pyrrolidine-2,5-diones.

  European journal of medicinal chemistry 20090201

• Spectroscopic evidence for an oxazolone structure of the b(2) fragment ion from protonated tri-alanine.

  Journal of the American Society for Mass Spectrometry 20090201

• Aurintricarboxylic acid inhibits influenza virus neuraminidase.

  Antiviral research 20090201

• Synthesis of novel Gn-RH analogues using Ugi-4MCR.

  Bioorganic & medicinal chemistry letters 20090201

• Novel HDAC6 isoform selective chiral small molecule histone deacetylase inhibitors.

  Bioorganic & medicinal chemistry letters 20090201

• A novel diketopiperazine improves functional recovery given after the onset of 6-OHDA-induced motor deficit in rats.

  British journal of pharmacology 20090201

• tert-Butyl 3-[N-(tert-butoxy-carbonyl)methyl-amino]-4-methoxy-imino-3-methyl-piperidine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20090201

• tert-Butyl 3-carbamoyl-4-methoxy-imino-3-methyl-piperidine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20090201

• Asymmetric synthesis of the ABC-ring system of the antitumor antibiotic MPC1001.

  The Journal of organic chemistry 20090116

• Design and synthesis of N-methylmaleimide indolocarbazole bearing modified 2-acetamino acid moieties as Topoisomerase I inhibitors.

  Bioorganic & medicinal chemistry letters 20090115

• Relationships between the structure of 6-allyl-6,8-diazabicyclo[3.2.2]nonane derivatives and their sigma receptor affinity and cytotoxic activity.

  Bioorganic & medicinal chemistry 20090115

• Synthesis of functional poly(phenyl isocyanide)s with macromolecular helicity memory and their use as asymmetric organocatalysts.

  Chirality 20090101

• Pleuromutilin derivatives having a purine ring. Part 3: synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer.

  Bioorganic & medicinal chemistry letters 20090101

• Efficient nucleic acid transduction with lipoplexes containing novel piperazine- and polyamine-conjugated cholesterol derivatives.

  Bioorganic & medicinal chemistry letters 20090101

• Direct zincation of functionalized aromatics and heterocycles by using a magnesium base in the presence of ZnCl2.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Biochemical and biological properties of 4-(3-phenyl-[1,2,4] thiadiazol-5-yl)-piperazine-1-carboxylic acid phenylamide, a mechanism-based inhibitor of fatty acid amide hydrolase.

  Anesthesia and analgesia 20090101

• Design and synthesis of piperazinylpyridine derivatives as novel 5-HT1A agonists/5-HT3 antagonists for the treatment of irritable bowel syndrome (IBS).

  Chemical & pharmaceutical bulletin 20090101

• An alternative convenient synthesis of piperidazine-3-carboxylic acid derivatives.

  Chemical & pharmaceutical bulletin 20090101

• Supramolecular complexation of N-alkyl- and N,N'-dialkylpiperazines with cucurbit[6]uril in aqueous solution and in the solid state.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

  BMC medical genomics 20090101

• Impact of GnRH ovarian stimulation protocols on intracytoplasmic sperm injection outcomes.

  Reproductive biology and endocrinology : RB&E 20090101

• Indole prenyltransferases from fungi: a new enzyme group with high potential for the production of prenylated indole derivatives.

  Current medicinal chemistry 20090101

• Triggering with HCG or GnRH agonist in GnRH antagonist treated oocyte donation cycles: a randomised clinical trial.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20090101

• Body mass index and body composition in adolescents treated with gonadotropin-releasing hormone analogue triptorelin depot for central precocious puberty: data at near final height.

  Neuroendocrinology 20090101

• Synthesis and pharmacological properties of new derivatives of 4-alkoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones.

  Acta poloniae pharmaceutica 20090101

• Drug treatment of paraphilic and nonparaphilic sexual disorders.

  Clinical therapeutics 20090101

• Comparative genomics of lactic acid bacteria reveals a niche-specific gene set.

  BMC microbiology 20090101

• Snapshot of iron response in Shewanella oneidensis by gene network reconstruction.

  BMC genomics 20090101

• Histoplasma capsulatum encodes a dipeptidyl peptidase active against the mammalian immunoregulatory peptide, substance P.

  PloS one 20090101

• A review of the use of exemestane in early breast cancer.

  Therapeutics and clinical risk management 20090101

• Impact of surgical and medical castration on serum testosterone level in prostate cancer patients.

  Urologia internationalis 20090101

• Degarelix and its therapeutic potential in the treatment of prostate cancer.

  Clinical interventions in aging 20090101

• Casopitant: a novel NK(1)-receptor antagonist in the prevention of chemotherapy-induced nausea and vomiting.

  Therapeutics and clinical risk management 20090101

• Integrative gene cloning and expression system for Streptomyces sp. US 24 and Streptomyces sp. TN 58 bioactive molecule producing strains.

  Journal of biomedicine & biotechnology 20090101

• [Effect of gonadotropin-releasing hormone-I agonist and gonadotropin-releasing hormone-II on endometrial carcinoma cell lines with different states of PTEN].

  Zhonghua fu chan ke za zhi 20090101

• [Case report: an intestinal obstruction due to ascariasis].

  Turkiye parazitolojii dergisi 20090101

• Growth outcome during GnRH agonist treatments for slowly progressive central precocious puberty.

  Neuroendocrinology 20090101

• Synthesis, characterization, antibacterial and anti-inflammatory activities of enoxacin metal complexes.

  Bioinorganic chemistry and applications 20090101

• Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity.

  BMC bioinformatics 20090101

• Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii.

  BMC microbiology 20090101

• Subcutaneous gonadotropin-releasing hormone agonist (triptorelin) test for diagnosing precocious puberty.

  Hormone research 20090101

• Restrictions of anthelmintic usage: perspectives and potential consequences.

  Parasites & vectors 20090101

• Diagnosis and control of anthelmintic-resistant Parascaris equorum.

  Parasites & vectors 20090101

• Impact of GnRH analogues on oocyte/embryo quality and embryo development in in vitro fertilization/intracytoplasmic sperm injection cycles: a case control study.

  Reproductive biology and endocrinology : RB&E 20090101

• Structural and functional similarity between the bacterial type III secretion system needle protein PrgI and the eukaryotic apoptosis Bcl-2 proteins.

  PloS one 20090101

• Unorthodox superficial palmar arch observed in a South Indian cadaver: a case report.

  Cases journal 20090101

• Rare cause of intestinal obstruction, Ascaris lumbricoides infestation: two case reports.

  Cases journal 20090101

• Trigger finger presenting secondary to leiomyoma: a case report.

  Journal of medical case reports 20090101

• Characterizing multisegment foot kinematics during gait in diabetic foot patients.

  Journal of neuroengineering and rehabilitation 20090101

• Triptorelin 6-month formulation in the management of patients with locally advanced and metastatic prostate cancer: an open-label, non-comparative, multicentre, phase III study.

  Clinical drug investigation 20090101

• BioDEAL: community generation of biological annotations.

  BMC medical informatics and decision making 20090101

• Perazine at therapeutic drug concentrations inhibits human cytochrome P450 isoenzyme 1A2 (CYP1A2) and caffeine metabolism--an in vitro study.

  Pharmacological reports : PR 20090101

• Use of a hydrolytic procedure and spectrometric methods in the structure elucidation of a thiocarbonyl analogue of sildenafil detected as an adulterant in an over-the-counter herbal aphrodisiac.

  Journal of AOAC International 20090101

• Reliability of measuring abductor hallucis muscle parameters using two different diagnostic ultrasound machines.

  Journal of foot and ankle research 20090101

• Design and Synthesis of Imidazopyrimidine Derivatives as Potent iNOS Dimerization Inhibitors.

  The open medicinal chemistry journal 20090101

• Comprehensive in silico prediction and analysis of chlamydial outer membrane proteins reflects evolution and life style of the Chlamydiae.

  BMC genomics 20090101

• Steered molecular dynamics simulations reveal the likelier dissociation pathway of imatinib from its targeting kinases c-Kit and Abl.

  PloS one 20090101

• The acidic domains of the Toc159 chloroplast preprotein receptor family are intrinsically disordered protein domains.

  BMC biochemistry 20090101

• Novel dinuclear platinum(II) complexes targets NFkappaB signaling pathway to induce apoptosis and inhibit metabolism of MCF-7 breast cancer cells.

  Folia histochemica et cytobiologica 20090101

• Simple spectrophotometric method for determination of paroxetine in tablets using 1,2-naphthoquinone-4-sulphonate as a chromogenic reagent.

  International journal of analytical chemistry 20090101

• A seizure attributed to ofloxacine in a woman undergoing detoxification for alcohol dependence.

  Case reports in medicine 20090101

• Various solvent systems for solubility enhancement of enrofloxacin.

  Indian journal of pharmaceutical sciences 20090101

• A docking model of human ribonucleotide reductase with flavin and phenosafranine.

  Bioinformation 20090101

• Estimation of synthetic accessibility score of drug-like molecules based on molecular complexity and fragment contributions.

  Journal of cheminformatics 20090101

• Ovarian hyperstimulation syndrome: current views on pathophysiology, risk factors, prevention, and management.

  Journal of experimental & clinical assisted reproduction 20090101

• Co-crystals: a novel approach to modify physicochemical properties of active pharmaceutical ingredients.

  Indian journal of pharmaceutical sciences 20090101

• Stabilization of quinapril by incorporating hydrogen bonding interactions.

  Indian journal of pharmaceutical sciences 20090101

• Synthesis and Antiviral Studies of Novel N-Sulphonamidomethyl piperazinyl Fluoroquinolones.

  Indian journal of pharmaceutical sciences 20090101

• Role of imatinib in the management of early, operable, and advanced GI stromal tumors (GISTs).

  OncoTargets and therapy 20090101

• Mechanism of action of and resistance to quinolones.

  Microbial biotechnology 20090101

• Poly[ethyl-enediaminium [di-μ-aqua-(μ(6)-benzene-1,2,4,5-tetra-carboxyl-ato-κO,O:O,O:O:O,O:O:O,O)dithallium(I)]].

  Acta crystallographica. Section E, Structure reports online 20090101

• Aqua-(1,10-phenanthroline)(pyridine-2,6-dicarboxyl-ato)nickel(II) pyridine-2,6-di-carboxylic acid solvate tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20090101

• IRMPD spectroscopy shows that AGG forms an oxazolone b2+ ion.

  Journal of the American Chemical Society 20081231

• Hypercrosslinked polymer microspheres with weak anion-exchange character. Preparation of the microspheres and their applications in pH-tuneable, selective extractions of analytes from complex environmental samples.

  Journal of chromatography. A 20081226

• Structurally constrained hybrid derivatives containing octahydrobenzo[g or f]quinoline moieties for dopamine D2 and D3 receptors: binding characterization at D2/D3 receptors and elucidation of a pharmacophore model.

  Journal of medicinal chemistry 20081225

• Synthesis and biological evaluation of homopiperazine derivatives with beta-aminoacyl group as dipeptidyl peptidase IV inhibitors.

  Bioorganic & medicinal chemistry letters 20081215

• Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.

  Chembiochem : a European journal of chemical biology 20081215

• Preparation and enantioseparation characteristics of a novel chiral stationary phase based on mono (6(A)-azido-6(A)-deoxy)-per(p-chlorophenylcarbamoylated) beta-cyclodextrin.

  Journal of chromatography. A 20081212

• Novel fluorescent pH sensor based on coumarin with piperazine and imidazole substituents.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081201

• Preoperative concurrent chemo- and endocrine therapies for women with large operable breast cancer expressing steroid hormone receptors.

  Breast (Edinburgh, Scotland) 20081201

• Gonadotropin-releasing hormone inhibits pituitary adenylyl cyclase-activating polypeptide coupling to 3',5'-cyclic adenosine-5'-monophosphate pathway in LbetaT2 gonadotrope cells through novel protein kinase C isoforms and phosphorylation of pituitary adenylyl cyclase-activating polypeptide type I receptor.

  Endocrinology 20081201

• [Camptodactyly].

  Chirurgie de la main 20081201

• A novel diketopiperazine stimulates sprouting of spinally projecting axons.

  Experimental neurology 20081201

• Second lumbrical and interossei latency difference in Carpal Tunnel Syndrome.

  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20081201

• Increased risk of metabolic syndrome, diabetes mellitus, and cardiovascular disease in men receiving androgen deprivation therapy for prostate cancer.

  Pharmacotherapy 20081201

• Synthesis and biological activities of neoechinulin A derivatives: new aspects of structure-activity relationships for neoechinulin A.

  Chemical & pharmaceutical bulletin 20081201

• [In-vitro screening of psychoactive drugs to prevent abuses].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081201

• Loss of translation elongation factor (eEF1A2) expression in vivo differentiates between Wallerian degeneration and dying-back neuronal pathology.

  Journal of anatomy 20081201

• Inappropriate sexual behaviors in cognitively impaired older individuals.

  The American journal of geriatric pharmacotherapy 20081201

• catena-Poly[[[(dimethyl-malonato-κO:O')(perchlorato-κO)copper(II)]-μ-bis-(3-pyridylmeth-yl)piperazinediium-κN:N] perchlorate dihydrate].

  Acta crystallographica. Section E, Structure reports online 20081201

• tert-Butyl 4-carbamoyl-3-methoxy-imino-4-methyl-piperidine-1-carboxyl-ate.

  Acta crystallographica. Section E, Structure reports online 20081201

• 4,4'-Dichloro-2,2'-(piperazine-1,4-diyldimethyl-ene)diphenol.

  Acta crystallographica. Section E, Structure reports online 20081201

• 6-Bromo-2-naphthol-piperazine (2/1).

  Acta crystallographica. Section E, Structure reports online 20081201

• A monoclinic polymorph of 4,4'-dichloro-2,2'-(piperazine-1,4-diyl-dimethyl-ene)diphenol.

  Acta crystallographica. Section E, Structure reports online 20081201

• An efficient approach to chiral C8/C9-piperazino-substituted 1,4-benzodiazepin-2-ones as peptidomimetic scaffolds.

  The Journal of organic chemistry 20081107

• Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities.

  Organic & biomolecular chemistry 20081107

• Synthesis of 5- and 6-carboxy-X-rhodamines.

  Organic letters 20081106

• Preoperative bevacizumab combined with letrozole and chemotherapy in locally advanced ER- and/or PgR-positive breast cancer: clinical and biological activity.

  British journal of cancer 20081104

• Chemistry of alpha-hydroxymethylserine: problems and solutions.

  Journal of peptide science : an official publication of the European Peptide Society 20081101

• Efficacy and safety of Technosphere inhaled insulin compared with Technosphere powder placebo in insulin-naive type 2 diabetes suboptimally controlled with oral agents.

  Diabetes care 20081101

• Metabolism of phenylahistin enantiomers by cytochromes P450: a possible explanation for their different cytotoxicity.

  Drug metabolism and disposition: the biological fate of chemicals 20081101

• Hormonal strategies for fertility preservation in patients receiving cyclophosphamide to treat glomerulonephritis: a nonrandomized trial and review of the literature.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20081101

• The limits of two-year bioassay exposure regimens for identifying chemical carcinogens.

  Environmental health perspectives 20081101

• [Efficacy and safety of long-acting gonadotropin-releasing hormone analogue in the treatment for metastatic prostate cancer].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20081101

• [Choroidal metastasis from clinically regressed prostate adenocarcinoma: imaging of a rare case].

  Journal francais d'ophtalmologie 20081101

• Diethyl-enetriaminium hexa-fluorido-titanate(IV) fluoride.

  Acta crystallographica. Section E, Structure reports online 20081101

• Multimetallic assemblies using piperazine-based dithiocarbamate building blocks.

  Inorganic chemistry 20081020

• 6-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors.

  Bioorganic & medicinal chemistry letters 20081015

• Synthesis and characterization of new piperazine-type inhibitors for mitochondrial NADH-ubiquinone oxidoreductase (complex I).

  Biochemistry 20081007

• Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability.

  Molecular pharmaceutics 20081006

• Can pregnancy rate be improved in gonadotropin-releasing hormone (GnRH) antagonist cycles by administering GnRH agonist before oocyte retrieval? A prospective, randomized study.

  Fertility and sterility 20081001

• Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine.

  Journal of the American Society for Mass Spectrometry 20081001

• The role of multihaem cytochromes in the respiration of nitrite in Escherichia coli and Fe(III) in Shewanella oneidensis.

  Biochemical Society transactions 20081001

• [Medicinal chemistry targeting nucleosides and nucleic acids based on fine synthetic chemistry].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081001

• Poly[[tetraaquabis(mu2-2-nitroterephthalato-kappa(3)O(1):O(4),O(4'))(mu2-piperazine-kappa(3)N:N')dicadmium(II)] dihydrate].

  Acta crystallographica. Section C, Crystal structure communications 20081001

• Plasmid-mediated quinolone resistance.

  Expert review of anti-infective therapy 20081001

• Synthesis and evaluation of novel radioiodinated nicotinamides for malignant melanoma.

  Nuclear medicine and biology 20081001

• Hemipiperazinediium bis-(pyridine-2,6-dicarboxyl-ato-κO,N,O')gallate(III) pyridine-2,6-dicarboxylic acid dihydrate.

  Acta crystallographica. Section E, Structure reports online 20081001

• 8-Chloro-5-(4-phenethylpiperazin-1--yl)pyrido[2,3-b][1,5]benzoxazepine.

  Acta crystallographica. Section E, Structure reports online 20081001

• 2-[(4-Benzhydrylpipérazin-1-yl)méthyl]acrylonitrile.

  Acta crystallographica. Section E, Structure reports online 20081001

• HIV, TB, Malaria, Filaria and Kala azar.

  Indian journal of pharmacology 20081001

• Synthesis and biological evaluation of 2-amino-3-(4-chlorobenzoyl)-4-[N-(substituted) piperazin-1-yl]thiophenes as potent allosteric enhancers of the A1 adenosine receptor.

  Journal of medicinal chemistry 20080925

• Expedient total syntheses of WIN 64745 and WIN 64821.

  Organic letters 20080904

• Synthesis of new 3-pyridinecarboxylates of potential vasodilation properties.

  European journal of medicinal chemistry 20080901

• 2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity.

  Bioorganic & medicinal chemistry letters 20080901

• Strategies to prevent N-acetyltransferase-mediated metabolism in a series of piperazine-containing pyrazalopyrimidine compounds.

  Xenobiotica; the fate of foreign compounds in biological systems 20080901

• Is a parallel elastic element responsible for the enhancement of steady-state muscle force following active stretch?

  The Journal of experimental biology 20080901

• N,N-Bis(trifluoromethylquinolin-4-yl)diamino alkanes: synthesis and antimalarial activity.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20080901

• Structure-activity relationship study of a series of N-substituted piperazinyl-fluoroquinolones as anti-Helicobacter pylori agents.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20080901

• [Effects of piperazine ferulate on connective tissue growth factor and extracellular matrix in TGF-beta1 induced mesangial cells].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080901

• [Effects of piperazine ferulate on TGF-beta1-induced renal interstitial fibroblast activation].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20080901

• [Synthesis and antibacterial activity of imidazothiadiazoles and heterocyclic-amine Mannich-base hydrochloride].

  Yao xue xue bao = Acta pharmaceutica Sinica 20080901

• Effect of temperature on residual force enhancement in single skeletal muscle fibers.

  Journal of biomechanics 20080828

• 2,6-Diazaspiro[3.3]heptanes: synthesis and application in Pd-catalyzed aryl amination reactions.

  Organic letters 20080821

• [Arm injuries due to sport climbing].

  Nederlands tijdschrift voor geneeskunde 20080816

• Novel dimeric aryldiketo containing inhibitors of HIV-1 integrase: effects of the phenyl substituent and the linker orientation.

  Bioorganic & medicinal chemistry 20080815

• Aminomethylpiperazines as selective urotensin antagonists.

  Bioorganic & medicinal chemistry letters 20080815

• Synthesis of new arylpiperazinylalkylthiobenzimidazole, benzothiazole, or benzoxazole derivatives as potent and selective 5-HT1A serotonin receptor ligands.

  Journal of medicinal chemistry 20080814

• Antitumor activity of bis-indole derivatives.

  Journal of medicinal chemistry 20080814

• Hydrogen-bond-induced hysteresis in the compression/relaxation of monolayer films.

  Journal of the American Chemical Society 20080806

• Stability and in vitro release profile of enalapril maleate from different commercially available tablets: possible therapeutic implications.

  Journal of pharmaceutical and biomedical analysis 20080805

• Copper(I) cyanide networks: synthesis, structure, and luminescence behavior. Part 2. Piperazine ligands and hexamethylenetetramine.

  Inorganic chemistry 20080804

• Cr(III), Fe(III) and Co(III) complexes of tetradentate (ONNO) Schiff base ligands: synthesis, characterization, properties and biological activity.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080801

• Synthesis, binding properties and receptor docking of 4-halo-6-[2-(4-arylpiperazin-1-yl)ethyl]-1H-benzimidazoles, mixed ligands of D2 and 5-HT1A receptors.

  European journal of medicinal chemistry 20080801

• Multivariate chemometric approach to thermal solid-state FT-IR monitoring of pharmaceutical drug compound.

  Journal of pharmaceutical sciences 20080801

• Model-based analysis for kinetic complexation study of Pizda and Cu(II).

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080801

• Development of benzophenone-based farnesyltransferase inhibitors as novel antimalarials.

  ChemMedChem 20080801

• Anomalous origin of the lumbrical muscles: a study on South Indian cadavers.

  Morphologie : bulletin de l'Association des anatomistes 20080801

• Elevation in heat shock protein 72 mRNA following contractions in isolated single skeletal muscle fibers.

  American journal of physiology. Regulatory, integrative and comparative physiology 20080801

• Electrochemical interrogations of the Mtr cytochromes from Shewanella: opening a potential window.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080801

• Design, synthesis, and biological evaluation of pirenzepine analogs bearing a 1,2-cyclohexanediamine and perhydroquinoxaline units in exchange for the piperazine ring as antimuscarinics.

  Bioorganic & medicinal chemistry 20080801

• Imidazole piperazines: SAR and development of a potent class of cyclin-dependent kinase inhibitors with a novel binding mode.

  Bioorganic & medicinal chemistry letters 20080801

• Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors.

  Bioorganic & medicinal chemistry letters 20080801

• Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide conjugates linked through piperazine side-armed alkane spacers.

  Bioorganic & medicinal chemistry 20080801

• Fine synthetic nucleoside chemistry based on nucleoside natural products synthesis.

  Chemical & pharmaceutical bulletin 20080801

• Three-dimensional frameworks built from piperazine-2,5-dione and simple metal salts (M = Co, Ni, Cu and Ag).

  Acta crystallographica. Section C, Crystal structure communications 20080801

• Off-target effects of psychoactive drugs revealed by genome-wide assays in yeast.

  PLoS genetics 20080801

• Kinetics of lisinopril intramolecular cyclization in solid phase monitored by Fourier transform infrared microscopy.

  Applied spectroscopy 20080801

• Comparison of clinical efficacy between a single administration of long-acting gonadotrophin-releasing hormone agonist (GnRHa) and daily administrations of short-acting GnRHa in in vitro fertilization-embryo transfer cycles.

  Journal of Korean medical science 20080801

• Probable case of neuroleptic malignant syndrome following administration of antituberculotic drugs in a chlorpromazine-treated patient.

  Journal of Korean medical science 20080801

• Utility of ranolazine in chronic stable angina patients.

  Vascular health and risk management 20080801

• Synthesis and biological evaluation of new imidazolium and piperazinium salts of pyropheophorbide-a for photodynamic cancer therapy.

  International journal of molecular sciences 20080801

• 2,2'-Biimidazolium hexa-aqua-manganese(II) bis-(sulfate).

  Acta crystallographica. Section E, Structure reports online 20080801

• 4-Benzhydryl-1-cinnamylpiperazin-1-ium nitrate.

  Acta crystallographica. Section E, Structure reports online 20080801

• 4-Benzyl-piperazin-1-ium chloride chloro-form solvate.

  Acta crystallographica. Section E, Structure reports online 20080801

• Piperazine sulfonamides as potent, selective, and orally available 11beta-hydroxysteroid dehydrogenase type 1 inhibitors with efficacy in the rat cortisone-induced hyperinsulinemia model.

  Journal of medicinal chemistry 20080724

• Synthesis and activity of N-cyanoguanidine-piperazine P2X7 antagonists.

  Bioorganic & medicinal chemistry letters 20080715

• Formulation of rifampicin-cyclodextrin complexes for lung nebulization.

  Journal of controlled release : official journal of the Controlled Release Society 20080714

• Use of N-methylpiperazine for the preparation of piperazine-based unsymmetrical bis-ureas as anti-HIV agents.

  ChemMedChem 20080701

• The c-type cytochrome OmcA localizes to the outer membrane upon heterologous expression in Escherichia coli.

  Journal of bacteriology 20080701

• Poloxamer 188 reduces the contraction-induced force decline in lumbrical muscles from mdx mice.

  American journal of physiology. Cell physiology 20080701

• 2-phenyl-4-piperazinylbenzimidazoles: orally active inhibitors of the gonadotropin releasing hormone (GnRH) receptor.

  Bioorganic & medicinal chemistry 20080701

• Two-dimensional QSAR studies on arylpiperazines as high-affinity 5-HT(1A) receptor ligands.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20080701

• Ozonation of ciprofloxacin in water: HRMS identification of reaction products and pathways.

  Environmental science & technology 20080701

• Tetra-kis(dihydrogen pefloxacinium) di-μ(2)-chlorido-bis-[tetra-chloridobismuthate(III)] tetra-chloride octa-hydrate.

  Acta crystallographica. Section E, Structure reports online 20080701

• 2-(4-Methyl-2-phenyl-piperazin-4-ium-1-yl)pyridine-3-carboxyl-ate dihydrate.

  Acta crystallographica. Section E, Structure reports online 20080701

• (2S,3R)-2-[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl-amino]-3-hydroxy-butyric acid monohydrate.

  Acta crystallographica. Section E, Structure reports online 20080701

• 4-(2,3-Dimethyl-phen-yl)piperazin-1-ium chloride monohydrate.

  Acta crystallographica. Section E, Structure reports online 20080701

• Synthesis of diketopiperazine-based carboline homodimers and in vitro growth inhibition of human carcinomas.

  Bioorganic & medicinal chemistry letters 20080615

• Comparison of the bioactivation potential of the antidepressant and hepatotoxin nefazodone with aripiprazole, a structural analog and marketed drug.

  Drug metabolism and disposition: the biological fate of chemicals 20080601

• Novel ORL1-selective antagonists with oral bioavailability and brain penetrability.

  Bioorganic & medicinal chemistry letters 20080601

• Gonadotropin-releasing hormone analog treatment for the prevention of treatment-related ovarian failure and infertility in women of reproductive age with Hodgkin lymphoma.

  Leukemia & lymphoma 20080601

• Gray hair in children on triptorelin treatment.

  International journal of dermatology 20080601

• Cytotoxic alkaloids and antibiotic nordammarane triterpenoids from the marine-derived fungus Aspergillus sydowi.

  Journal of natural products 20080601

• Development of novel 68Ga- and 18F-labeled GnRH-I analogues with high GnRHR-targeting efficiency.

  Bioconjugate chemistry 20080601

• [Analytical data of designated substances (Shitei-Yakubutsu) controlled by the Pharmaceutical Affairs Law in Japan, part I: GC-MS and LC-MS].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080601

• [Analytical data of designated substances (Shitei-Yakubutsu) controlled by the Pharmaceutical Affairs Law in Japan, part II: Color test and TLC].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080601

• Insulin-like growth factor-1 and its derivatives: potential pharmaceutical application for ischemic brain injury.

  Recent patents on CNS drug discovery 20080601

• [A study on the NMR spectrum of methyl-ofloxacin].

  Guang pu xue yu guang pu fen xi = Guang pu 20080601

• [Synthesis and central none-opioid analgesic activity of SIPI5047].

  Yao xue xue bao = Acta pharmaceutica Sinica 20080601

• Care, husbandry and diseases of the African giant rat (Cricetomys gambianus).

  Journal of the South African Veterinary Association 20080601

• 2-[2-(4-Benzyl-piperazin-1-ylcarbon-yl)eth-yl]-5,6-diphenyl-pyridazin-3(2H)-one.

  Acta crystallographica. Section E, Structure reports online 20080601

• Spiro[(dihydropyrazin-2,5-dione)-6,3'-(2',3'-dihydrothieno[2,3-b]naphtho-4',9'-dione)]-based cytotoxic agents: structure-activity relationship studies on the substituent at N4-position of the diketopiperazine domain.

  Journal of medicinal chemistry 20080522

• Preparation of piperazine derivatives as 5-HT7 receptor antagonists.

  Bioorganic & medicinal chemistry 20080515

• Synthesis and in vitro antimycobacterial activity of B-ring modified diaryl ether InhA inhibitors.

  Bioorganic & medicinal chemistry letters 20080515

• In vitro evolution of a peptide with a hematite binding motif that may constitute a natural metal-oxide binding archetype.

  Environmental science & technology 20080515

• Practical synthesis of a vanilloid receptor-1 antagonist.

  The Journal of organic chemistry 20080502

• Biotransformation of 3-amino-5,6,7,8-tetrahydro-2-{4-[4-(quinolin-2-yl)piperazin-1-yl]butyl}quinazolin-4(3H)-one (TZB-30878), a novel 5-hydroxytryptamine (5-HT)1A agonist/5-HT3 antagonist, in human hepatic cytochrome P450 enzymes.

  Drug metabolism and disposition: the biological fate of chemicals 20080501

• Synthesis and structure-antibacterial activity of triazolyl oxazolidinones containing long chain acyl moiety.

  European journal of medicinal chemistry 20080501

• Rapid screening for cyclo-dopa and diketopiperazine alkaloids in crude extracts of Portulaca oleracea L. using liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20080501

• Internal pH indicators for biomolecular NMR.

  Journal of biomolecular NMR 20080501

• High growth rate of girls with precocious puberty exposed to estrogenic mycotoxins.

  The Journal of pediatrics 20080501

• Characterization of intermediate compounds formed upon photoinduced degradation of quinolones by high-performance liquid chromatography/high-resolution multiple-stage mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20080501

• Butane-1,4-diammonium bis-(pyridine-2,6-dicarboxyl-ato)cuprate(II) trihydrate.

  Acta crystallographica. Section E, Structure reports online 20080501

• (2S,4aR,3S,8aR,9R,10R)-1,4-Diallyl-2,3-diphenyl-perhydro-quinoxaline.

  Acta crystallographica. Section E, Structure reports online 20080501

• Electrogenerated chemiluminescence: an oxidative-reductive mechanism between quinolone antibiotics and tris(2,2'-bipyridyl)ruthenium(II).

  Analytica chimica acta 20080421

• Synthesis and structure-activity relationship studies on tryprostatin A, an inhibitor of breast cancer resistance protein.

  Bioorganic & medicinal chemistry 20080415

• Synthesis and in vitro anti-leishmanial activity of 1-[5-(5-nitrofuran-2-yl)-1,3,4-thiadiazol-2-yl]- and 1-[5-(5-nitrothiophen-2-yl)-1,3,4-thiadiazol-2-yl]-4-aroylpiperazines.

  Bioorganic & medicinal chemistry 20080415

• DNA threading bis(9-aminoacridine-4-carboxamides): effects of piperidine sidechains on DNA binding, cytotoxicity and cell cycle arrest.

  Bioorganic & medicinal chemistry 20080415

• Practical experiences with the synthesis of [11C]CH3I through gas phase iodination reaction using a TRACERlabFXC synthesis module.

  Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20080401

• Direct and indirect cellular effects of aspartame on the brain.

  European journal of clinical nutrition 20080401

• The influence of cultivation methods on Shewanella oneidensis physiology and proteome expression.

  Archives of microbiology 20080401

• Mechanism of action of the new anti-ischemia drug ranolazine.

  Clinical research in cardiology : official journal of the German Cardiac Society 20080401

• Selective vulnerability of motor neurons and dissociation of pre- and post-synaptic pathology at the neuromuscular junction in mouse models of spinal muscular atrophy.

  Human molecular genetics 20080401

• Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands.

  Bioorganic & medicinal chemistry 20080401

• Prevention of ovarian function damage by a GnRH analogue during chemotherapy in Hodgkin lymphoma patients.

  Human reproduction (Oxford, England) 20080401

• Phosphonate-linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates: synthesis, DNA-binding affinity and cytotoxicity.

  Bioorganic & medicinal chemistry 20080401

• In vivo identification of the outer membrane protein OmcA-MtrC interaction network in Shewanella oneidensis MR-1 cells using novel hydrophobic chemical cross-linkers.

  Journal of proteome research 20080401

• Histoplasma requires SID1, a member of an iron-regulated siderophore gene cluster, for host colonization.

  PLoS pathogens 20080401

• A new diketopiperazine alkaloid isolated from an algicolous Aspergillus flavus strain.

  Die Pharmazie 20080401

• Three-dimensional network in piper-azine-1,4-diium-picrate-piperazine (1/2/1).

  Acta crystallographica. Section E, Structure reports online 20080401

• Bis(piperazinediium) benzene-1,2,4,5-tetra-carboxyl-ate hexa-hydrate.

  Acta crystallographica. Section E, Structure reports online 20080401

• Patent Toxocara canis infections in previously exposed and in helminth-free dogs after infection with low numbers of embryonated eggs.

  Veterinary parasitology 20080325

• Location and orientation of serotonin receptor 1a agonists in model and complex lipid membranes.

  The Journal of biological chemistry 20080321

• 1-, 3- and 8-substituted-9-deazaxanthines as potent and selective antagonists at the human A2B adenosine receptor.

  Bioorganic & medicinal chemistry 20080315

• Synthesis and in vitro activity of N'-cyano-4-(2-phenylacetyl)-N-o-tolylpiperazine-1-carboximidamide P2X7 antagonists.

  Bioorganic & medicinal chemistry letters 20080315

• Biomimetic fat cell (BFC) modification and for lindane removal from aqueous solution.

  Journal of hazardous materials 20080301

• Side effects of pharmacotherapy on bone with long-acting gonadorelin agonist triptorelin for paraphilia.

  The journal of sexual medicine 20080301

• GnRH agonist protocol administration in the luteal phase in ICSI-ET cycles stimulated with the long GnRH agonist protocol: a randomized, controlled double blind study.

  Human reproduction (Oxford, England) 20080301

• Luteal phase support with GnRH-a improves implantation and pregnancy rates in IVF cycles with endometrium of <or=7 mm on day of egg retrieval.

  Human fertility (Cambridge, England) 20080301

• Role of biotransformation studies in minimizing metabolism-related liabilities in drug discovery.

  The AAPS journal 20080301

• N-Phosphino-amidines and -guanidines: synthesis, structure and P,N-chelate chemistry.

  Dalton transactions (Cambridge, England : 2003) 20080227

• Parenteral oestrogen in the treatment of prostate cancer: a systematic review.

  British journal of cancer 20080226

• Anti-inflammatory and anthelmintic activities of Solanum khasianum Clarke.

  Natural product research 20080215

• A randomized study comparing triptorelin or expectant management following conservative laparoscopic surgery for symptomatic stage III-IV endometriosis.

  European journal of obstetrics, gynecology, and reproductive biology 20080201

• Crystal structure and vibrational spectra of piperazinium bis(4-hydroxybenzenesulphonate) molecular-ionic crystal.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080201

• Design, synthesis and preliminary pharmacological evaluation of new piperidine and piperazine derivatives as cognition-enhancers.

  Bioorganic & medicinal chemistry 20080201

• Design of new potent and selective secretory phospholipase A2 inhibitors. Part 5: synthesis and biological activity of 1-alkyl-4-[4,5-dihydro-1,2,4-[4H]-oxadiazol-5-one-3-ylmethylbenz-4'-yl(oyl)] piperazines.

  Bioorganic & medicinal chemistry 20080201

• Effect of a gonadotrophin-releasing hormone analogue on lung function in lymphangioleiomyomatosis.

  Chest 20080201

• Synthetic study of VLA-4/VCAM-1 inhibitors: synthesis and structure-activity relationship of piperazinylphenylalanine derivatives.

  Bioorganic & medicinal chemistry letters 20080201

• Direct observation of failing fibers in muscles of dystrophic mice provides mechanistic insight into muscular dystrophy.

  American journal of physiology. Cell physiology 20080201

• Synthesis and evaluation of some xanthone derivatives for anti-arrhythmic, hypotensive properties and their affinity for adrenergic receptors.

  Archiv der Pharmazie 20080201

• catena-Poly[[triaqua-cadmium(II)]-μ-pyridine-2,3-dicarboxyl-ato-κN,O:O].

  Acta crystallographica. Section E, Structure reports online 20080201

• Tris(piperazinediium) bis-[tris-(pyridine-2,6-dicarboxyl-ato)neodymate(III)] 15.33-hydrate.

  Acta crystallographica. Section E, Structure reports online 20080201

• Poly[piperazinediium [[aqua-bismuth-ate(III)]-di-μ-pyridine-2,6-dicarboxyl-ato-bis-muthate(III)-di-μ-pyridine-2,6-dicarboxyl-ato] monohydrate].

  Acta crystallographica. Section E, Structure reports online 20080201

• Bis(dihydrogen norfloxacinium) tri-μ(2)-chlorido-bis-[trichloridobismuthate(III)] chloride dihydrate.

  Acta crystallographica. Section E, Structure reports online 20080201

• 1-Benzhydryl-4-(4-chloro-phenyl-sulfonyl)piperazine.

  Acta crystallographica. Section E, Structure reports online 20080201

• Cyclo(l-tyrosyl-l-tryptophanyl) dimethylformamide solvate.

  Acta crystallographica. Section E, Structure reports online 20080201

• Synthesis and conformational studies of peptidomimetics containing a new bifunctional diketopiperazine scaffold acting as a beta-hairpin inducer.

  The Journal of organic chemistry 20080118

• Star-shaped mesogens of triazine-based dendrons and dendrimers as unconventional columnar liquid crystals.

  The Journal of organic chemistry 20080118

• Pharmacomodulation on the 3-acetylursolic acid skeleton: Design, synthesis, and biological evaluation of novel N-{3-[4-(3-aminopropyl)piperazinyl]propyl}-3-O-acetylursolamide derivatives as antimalarial agents.

  Bioorganic & medicinal chemistry 20080115

• Synthesis and structure-activity relationship studies of tyrosine-based antagonists at the human P2X7 receptor.

  Bioorganic & medicinal chemistry letters 20080115

• Endocrine effects of adjuvant letrozole + triptorelin compared with tamoxifen + triptorelin in premenopausal patients with early breast cancer.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080110

• Study of forced degradation behavior of enalapril maleate by LC and LC-MS and development of a validated stability-indicating assay method.

  Journal of pharmaceutical and biomedical analysis 20080107

• Hydrogenase- and outer membrane c-type cytochrome-facilitated reduction of technetium(VII) by Shewanella oneidensis MR-1.

  Environmental microbiology 20080101

• Design and synthesis of diketopiperazine and acyclic analogs related to the caprazamycins and liposidomycins as potential antibacterial agents.

  Bioorganic & medicinal chemistry 20080101

• Height gain with combined growth hormone and gonadotropin-releasing hormone analog therapy in two pubertal siblings with a growth hormone-releasing hormone receptor mutation.

  The Journal of clinical endocrinology and metabolism 20080101

• Increase of doxorubicin-induced apoptosis after knock-down of gonadotropin-releasing hormone receptor expression in human endometrial, ovarian and breast cancer cells.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080101

• Isostructural materials achieved by using structurally equivalent donors and acceptors in halogen-bonded cocrystals.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• Prebiotic thermal polymerization of crystals of amino acids via the diketopiperazine reaction.

  Bio Systems 20080101

• Analysis of epipolythiodioxopiperazines in fungus Chaetomium cochliodes using HPLC-ESI-MS/MS/MS.

  Analytical chemistry 20080101

• Synthesis and biological activity of piperazine and diazepane amides that are histamine H3 antagonists and serotonin reuptake inhibitors.

  Bioorganic & medicinal chemistry letters 20080101

• Synthesis and antibacterial activity of quinolone-based compounds containing a coumarin moiety.

  Archiv der Pharmazie 20080101

• Metabolic efficiency with ranolazine for less ischemia in non-ST elevation acute coronary syndromes (MERLIN TIMI-36) study.

  Expert review of cardiovascular therapy 20080101

• A diketopiperazine fragment of human serum albumin modulates T-lymphocyte cytokine production through rap1.

  The Journal of trauma 20080101

• Biomimetic catalysis of diketopiperazine and dipeptide syntheses.

  Angewandte Chemie (International ed. in English) 20080101

• Unusual presentation of hereditary neuropathy with liability to pressure palsies.

  Journal of brachial plexus and peripheral nerve injury 20080101

• Probing regulon of ArcA in Shewanella oneidensis MR-1 by integrated genomic analyses.

  BMC genomics 20080101

• Human infection with Moniliformis moniliformis (Bremser 1811) (Travassos 1915) in Iran: another case report after three decades.

  Vector borne and zoonotic diseases (Larchmont, N.Y.) 20080101

• Endocrine modifications associated with final oocyte maturation with gonadotropin-releasing hormone agonists vs. human chorionic gonadotropin in women undergoing intrauterine insemination.

  The Journal of reproductive medicine 20080101

• A delineation of diketopiperazine self-assembly processes: understanding the molecular events involved in Nepsilon-(fumaroyl)diketopiperazine of L-Lys (FDKP) interactions.

  Molecular pharmaceutics 20080101

• Molecular Pacman: folding, inclusion, and X-ray structures of tri- and tetraamino piperazine cyclophanes.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

• The origin of the premotor potential recorded from the second lumbrical.

  Electromyography and clinical neurophysiology 20080101

• Piperazine protects the rat heart against sudden cardiac death from barium chloride-induced ventricular fibrillation.

  American journal of therapeutics 20080101

• Characterization of the Shewanella oneidensis Fur gene: roles in iron and acid tolerance response.

  BMC genomics 20080101

• Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3.

  PloS one 20080101

• [Repercussions of the withdrawal of thioridazine].

  Actas espanolas de psiquiatria 20080101

• Compatible solute influence on nucleic acids: many questions but few answers.

  Saline systems 20080101

• Crystal structures of 2-aminotropone, n,n'-di(tropon-2-yl)piperazine, and 5-(4-ethoxyphenylazo)tropolone.

  Journal of oleo science 20080101

• An additional muscle belly of the first lumbrical muscle.

  Cases journal 20080101

• Chemistry and structure-activity relationship of antibacterial nucleoside natural products.

  Nucleic acids symposium series (2004) 20080101

• Physicochemical, pharmacological and pharmacokinetic properties of the zwitterionic antihistamines cetirizine and levocetirizine.

  Current medicinal chemistry 20080101

• Role of endocrine responsiveness and HER2/neu overexpression in inflammatory breast cancer treated with multimodality preoperative therapy.

  The breast journal 20080101

• Ultrasound evaluation of the abductor hallucis muscle: Reliability study.

  Journal of foot and ankle research 20080101

• Assessment of data processing to improve reliability of microarray experiments using genomic DNA reference.

  BMC genomics 20080101

• Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation.

  Proteome science 20080101

• [Physico-chemical profiling of centrally acting molecules for prediction of pharmacokinetic properties].

  Acta pharmaceutica Hungarica 20080101

• Ranolazine: a review of its use in chronic stable angina pectoris.

  Drugs 20080101

• Improved machine learning method for analysis of gas phase chemistry of peptides.

  BMC bioinformatics 20080101

• targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis.

  BMC systems biology 20080101

• Synthesis, characterization, and in vitro cytotoxic activities of benzaldehyde thiosemicarbazone derivatives and their palladium (II) and platinum (II) complexes against various human tumor cell lines.

  Bioinorganic chemistry and applications 20080101

• Application of sequence-dependent electrophoresis fingerprinting in exploring biodiversity and population dynamics of human intestinal microbiota: what can be revealed?

  Interdisciplinary perspectives on infectious diseases 20080101

• ECRL--a wrist extensor with multiple uses in deformity correction.

  Indian journal of leprosy 20080101

• Gonadotrophin releasing hormone antagonist in IVF/ICSI.

  Journal of human reproductive sciences 20080101

• In Vitro Anthelmintic Activity of Baliospermum montanum Muell. Arg roots.

  Indian journal of pharmaceutical sciences 20080101

• Poly[piperazinediium [aqua-bis(μ-pyridine-2,5-dicarboxyl-ato)zincate] dihydrate].

  Acta crystallographica. Section E, Structure reports online 20080101

• (Piperazin-1-ium-κN)tris-(thio-cyanato-κN)zinc(II).

  Acta crystallographica. Section E, Structure reports online 20080101

• Bis(2,4,6-triamino-1,3,5-triazin-1-ium) hexa-aqua-cobalt(II) bis-[bis-(pyridine-2,6-dicarboxyl-ato)cobaltate(II)] tetra-hydrate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Poly[[tetra-aqua-bis[μ(3)-1-ethyl-6-fluoro-4-oxo-7-(piperazinium-1-yl)-1H-quinoline-3-carboxyl-ato]dinickel(II)] hydroxide nitrate].

  Acta crystallographica. Section E, Structure reports online 20080101

• N,N'-Dibenzyl-N,N,N',N'-tetra-methyl-ethylenediammonium dibromide dihydrate.

  Acta crystallographica. Section E, Structure reports online 20080101

• 1-Isopropyl-4-tosyl-piperazin-1-ium trifluoro-acetate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Piperazinediium bis-(2-carboxy-pyridine-3-carboxyl-ate).

  Acta crystallographica. Section E, Structure reports online 20080101

• 2,3,4-Triacet-oxy-1-[5-(1,2,3,4-tetra-acetoxy-butyl)pyrazin-2-yl]butyl acetate.

  Acta crystallographica. Section E, Structure reports online 20080101

• Evaluation of anthelmintic activity of nuts of Semecarpus anacardium.

  Ancient science of life 20080101

• Synthesis and characterization of trans-4-(4-chlorophenyl)pyrrolidine-3-carboxamides of piperazinecyclohexanes as ligands for the melanocortin-4 receptor.

  Bioorganic & medicinal chemistry letters 20071215

• Synthesis and antibacterial activity of potent heterocyclic oxazolidinones and the identification of RBx 8700.

  Bioorganic & medicinal chemistry letters 20071215

• Trypanocidal activity of piperazine-linked bisbenzamidines and bisbenzamidoxime, an orally active prodrug.

  International journal of antimicrobial agents 20071201

• Multivariate data analysis as a tool to investigate the reaction kinetics of intramolecular cyclization of enalapril maleate studied by isothermal and non-isothermal FT-IR microscopy.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20071201

• Clinical pharmacokinetics of norfloxacin-glycine acetate after intravenous and oral administration in pigs.

  Journal of veterinary science 20071201

• Ion-channels on parasite muscle: pharmacology and physiology.

  Invertebrate neuroscience : IN 20071201

• Monohydrous dihydrogen phosphate salts of norfloxacin and ciprofloxacin.

  Acta crystallographica. Section C, Crystal structure communications 20071201

• Leuprorelin, triptorelin: new indications. Locally advanced prostate cancer: minimally assessed me-toos.

  Prescrire international 20071201

• Conservative treatment for round worm intestinal obstruction.

  Indian journal of pediatrics 20071201

• Discovery of 5-HT6 receptor ligands based on virtual HTS.

  Bioorganic & medicinal chemistry letters 20071115

• Mechanisms of electron transfer in two decaheme cytochromes from a metal-reducing bacterium.

  The journal of physical chemistry. B 20071108

• Atrazine removal by covalent bonding to piperazine functionalized PolyHIPEs.

  The Science of the total environment 20071101

• Design and synthesis of thiazole-5-hydroxamic acids as novel histone deacetylase inhibitors.

  Bioorganic & medicinal chemistry letters 20071101

• Amino(methyl) pyrrolidines as novel scaffolds for factor Xa inhibitors.

  Bioorganic & medicinal chemistry letters 20071101

• Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia-ischemia in adult rats.

  Neuropharmacology 20071101

• Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of piperaquine in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101

• Citromycetins and bilains A-C: new aromatic polyketides and diketopiperazines from Australian marine-derived and terrestrial Penicillium spp.

  Journal of natural products 20071101

• [Clinical and electrophysiological findings in carpal tunnel syndrome].

  Brain and nerve = Shinkei kenkyu no shinpo 20071101

• [Study of new blended chemical absorbents to absorb CO2].

  Huan jing ke xue= Huanjing kexue 20071101

• [Design and synthesis of aralkyl-ketone piperazine derivatives and their antalgic activities].

  Yao xue xue bao = Acta pharmaceutica Sinica 20071101

• In situ ligand reactions under hydrothermal conditions afford a novel zinc-substituted polyoxovanadate dimer.

  Inorganic chemistry 20071029

• Ovulation induced by mucosa vaginal absorption of buserelin and triptorelin in rabbit.

  Theriogenology 20071015

• Macrocyclic diketopiperazine receptors: effect of macrocyclization on the binding properties of two-armed receptors.

  Organic letters 20071011

• Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for Less Ischemia in Non ST-Elevation Acute Coronary Syndrome Thrombolysis in Myocardial Infarction 36 (MERLIN-TIMI 36) randomized controlled trial.

  Circulation 20071009

• Synthesis of bridged piperazines with sigma receptor affinity.

  European journal of medicinal chemistry 20071001

• Can studies of the second lumbrical interossei and its premotor potential reduce the number of tests for carpal tunnel syndrome?

  Muscle & nerve 20071001

• The effects of JWB1-84-1 on memory-related task performance by amyloid Abeta transgenic mice and by young and aged monkeys.

  Neuropharmacology 20071001

• New organically templated copper(I) sulfites: the role of sulfite anion as both soft and hard ligand.

  Inorganic chemistry 20071001

• Synthesis and antimicrobial evaluation of new chalcones containing piperazine or 2,5-dichlorothiophene moiety.

  Bioorganic & medicinal chemistry letters 20071001

• Structure-activity relationships of neoechinulin A analogues with cytoprotection against peroxynitrite-induced PC12 cell death.

  The Journal of antibiotics 20071001

• [Granuloma at the injection site of leuprorelin acetate: foreign body reaction to polylactic acid].

  Annales de dermatologie et de venereologie 20071001

• Threaded structure and blue luminescence of (CuCN)20(Piperazine)7.

  Chemical communications (Cambridge, England) 20070928

• Antitumour and biological effects of letrozole and GnRH analogue as primary therapy in premenopausal women with ER and PgR positive locally advanced operable breast cancer.

  British journal of cancer 20070911

• In vitro cytotoxicity and phototoxicity of N-piperazinyl quinolone derivatives with a 2-thienyl group.

  Toxicology in vitro : an international journal published in association with BIBRA 20070901

• Synthesis and antibacterial activity of novel oxazolidinones with methylene oxygen- and methylene sulfur-linked substituents at C5-position.

  Bioorganic & medicinal chemistry letters 20070901

• Clinical outcome with half-dose depot triptorelin is the same as reduced-dose daily buserelin in a long protocol of controlled ovarian stimulation for ICSI/embryo transfer: a randomized double-blind clinical trial (NCT00461916).

  Human reproduction (Oxford, England) 20070901

• Monoclinic and orthorhombic polymorphs of 4,4',6,6'-tetrachloro-2,2'-(piperazine-1,4-diyldimethylene)diphenol.

  Acta crystallographica. Section C, Crystal structure communications 20070901

• 1-cinnamyl-4-(2-methoxyphenyl)piperazines: synthesis, binding properties, and docking to dopamine (D(2)) and serotonin (5-HT(1A)) receptors.

  Archiv der Pharmazie 20070901

• Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats.

  Environmental health perspectives 20070901

• Synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxypropyl]-pyrrolidin-2-one derivatives with anti-arrhythmic, hypotensive, and alpha-adrenolytic activity.

  Archiv der Pharmazie 20070901

• Spontaneous flexor tendon ruptures of the hand: case series and review of the literature.

  The Journal of hand surgery 20070901

• Comparison of the bioactive secondary metabolites from the scale insect pathogens, Anamorph Paecilomyces cinnamomeus, and Teleomorph Torrubiella luteorostrata.

  The Journal of antibiotics 20070901

• Structure-activity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a class of 5-HT7 receptor agents. 2.

  Journal of medicinal chemistry 20070823

• Forward- and reverse-synthesis of piperazinopiperidine amide analogs: a general access to structurally diverse 4-piperazinopiperidine-based CCR5 antagonists.

  Organic & biomolecular chemistry 20070821

• Cycloalkanediamine derivatives as novel blood coagulation factor Xa inhibitors.

  Bioorganic & medicinal chemistry letters 20070815

• Hydrothermal synthesis of a novel uranium oxalate/glycolate via in-situ ligand formation.

  Inorganic chemistry 20070806

• Additional flexor muscles of the forearm: case report and clinical significance.

  Singapore medical journal 20070801

• Electromyographic activities during isometric contraction of interphalangeal joint extensors of the finger.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20070801

• [Synthesis and antibacterial activity of N-(aroylalkyl) ciprofloxacin].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070801

• Diastereoselective synthesis of quaternary alpha-amino acids from diketopiperazine templates.

  Organic & biomolecular chemistry 20070707

• Synthesis and antibacterial activity of levofloxacin derivatives with certain bulky residues on piperazine ring.

  European journal of medicinal chemistry 20070701

• Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.

  Bioorganic & medicinal chemistry letters 20070701

• Respiration of metal (hydr)oxides by Shewanella and Geobacter: a key role for multihaem c-type cytochromes.

  Molecular microbiology 20070701

• A kinetic approach to the dependence of dissimilatory metal reduction by Shewanella oneidensis MR-1 on the outer membrane cytochromes c OmcA and OmcB.

  The FEBS journal 20070701

• Degradable cisplatin-releasing core-shell nanogels from zwitterionic poly(beta -aminoester)-graft-PEG for cancer chemotherapy.

  Drug delivery 20070701

• Fixed drug eruption to cetirizine with positive lesional patch tests to the three piperazine derivatives.

  International journal of dermatology 20070701

• A Mechanistic Approach for Modulation of Arsenic Toxicity in Human Lymphocytes by Curcumin, an Active Constituent of Medicinal Herb Curcuma longa Linn.

  Journal of clinical biochemistry and nutrition 20070701

• Separation of common organic and inorganic anions in atmospheric aerosols using a piperazine buffer and capillary electrophoresis.

  Journal of chromatography. A 20070622

• DNA interactions of new cytotoxic tetrafunctional dinuclear platinum complex trans,trans-[{PtCl2(NH3)}2(piperazine)].

  Biochemical pharmacology 20070615

• Oxidation of cyclic dipeptides by photoinduced H-atom abstraction. A laser flash FT EPR and optical spectroscopy study.

  The journal of physical chemistry. A 20070614

• Population pharmacokinetic/pharmacodynamic (PK/PD) modelling of the hypothalamic-pituitary-gonadal axis following treatment with GnRH analogues.

  British journal of clinical pharmacology 20070601

• Sensitive and rapid liquid chromatography/tandem mass spectrometric assay for the quantification of chloroquine in dog plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601

• Genotoxicity of 2-(3-chlorobenzyloxy)-6-(piperazinyl)pyrazine, a novel 5-hydroxytryptamine2c receptor agonist for the treatment of obesity: role of metabolic activation.

  Drug metabolism and disposition: the biological fate of chemicals 20070601

• Metabolism of prazosin in rat, dog, and human liver microsomes and cryopreserved rat and human hepatocytes and characterization of metabolites by liquid chromatography/tandem mass spectrometry.

  Drug metabolism and disposition: the biological fate of chemicals 20070601

• Electrophoretic affinity measurements on microchip. Determination of binding affinities between diketopiperazine receptors and peptide ligands.

  Electrophoresis 20070601

• Electrospray tandem mass spectrometry of epipolythiodioxopiperazines.

  Journal of mass spectrometry : JMS 20070601

• Synthesis and antibacterial activity of new N-[2-(thiophen-3-yl)ethyl] piperazinyl quinolones.

  Chemical & pharmaceutical bulletin 20070601

• Quinazolinone fungal efflux pump inhibitors. Part 3: (N-methyl)piperazine variants and pharmacokinetic optimization.

  Bioorganic & medicinal chemistry letters 20070515

• Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 5: 2'-Substituted 6-nitroquipazines.

  Bioorganic & medicinal chemistry 20070515

• Elective cryopreservation of all pronuclear oocytes after GnRH agonist triggering of final oocyte maturation in patients at risk of developing OHSS: a prospective, observational proof-of-concept study.

  Human reproduction (Oxford, England) 20070501

• [(S)-gamma-(4-Aryl-1-piperazinyl)-l-prolyl]thiazolidines as a novel series of highly potent and long-lasting DPP-IV inhibitors.

  Bioorganic & medicinal chemistry letters 20070501

• Synthesis and inhibition of cancer cell proliferation of (1,3')-bis-tetrahydroisoquinolines and piperazine systems.

  Bioorganic & medicinal chemistry letters 20070501

• Legal piperazine-containing party pills--a new trend in substance misuse.

  Drug and alcohol review 20070501

• Piperazine designer drugs of abuse.

  Lancet (London, England) 20070428

• Synthesis, characterization, and photochromic properties of hybrid organic-inorganic materials based on molybdate, DABCO, and piperazine.

  Inorganic chemistry 20070402

• Metabolism and excretion of the dipeptidyl peptidase 4 inhibitor [14C]sitagliptin in humans.

  Drug metabolism and disposition: the biological fate of chemicals 20070401

• Characterization of two cyclic metabolites of sitagliptin.

  Drug metabolism and disposition: the biological fate of chemicals 20070401

• Disposition of the dipeptidyl peptidase 4 inhibitor sitagliptin in rats and dogs.

  Drug metabolism and disposition: the biological fate of chemicals 20070401

• The contribution of oxazolidinone frame to the biological activity of pharmaceutical drugs and natural products.

  Mini reviews in medicinal chemistry 20070401

• Synthesis and in vitro evaluation of substituted phenyl-piperazinyl-phenyl oxazolidinones against Gram-positive bacteria.

  Chemical biology & drug design 20070401

• [Multicentre randomized trial comparing triptorelin medical castration versus surgical castration in the treatment of locally advanced or metastatic prostate cancer].

  Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20070401

• Analgesic and antiinflammatory activities of some new Mannich bases of 5-nitro-2-benzoxazolinones.

  Archives of pharmacal research 20070401

• [Laparoscopic hysterectomy after GnRh analogue therapy].

  Minerva ginecologica 20070401

• 5(6)-Carboxyfluorescein diacetate as an indicator of Caenorhabditis elegans viability for the development of an in vitro anthelmintic drug assay.

  Talanta 20070330

• The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain.

  European journal of pharmacology 20070322

• Novel piperazines: potent melanocortin-4 receptor antagonists with anxiolytic-like activity.

  Bioorganic & medicinal chemistry 20070315

• Copper(II) cyclam-based complexes for radiopharmaceutical applications: synthesis and structural analysis.

  Dalton transactions (Cambridge, England : 2003) 20070307

• Trimetazidine improves post-ischemic recovery by preserving endothelial nitric oxide synthase expression in isolated working rat hearts.

  Nitric oxide : biology and chemistry 20070301

• Limiting racemization and aspartimide formation in microwave-enhanced Fmoc solid phase peptide synthesis.

  Journal of peptide science : an official publication of the European Peptide Society 20070301

• Use of gonadotropin-releasing hormone agonists in patients with Hodgkin's disease for preservation of ovarian function and reduction of gonadotoxicity related to chemotherapy.

  Fertility and sterility 20070301

• Identification of metabolites produced from N-phenylpiperazine by Mycobacterium spp.

  Journal of industrial microbiology & biotechnology 20070301

• Potent, selective, and orally active adenosine A2A receptor antagonists: arylpiperazine derivatives of pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines.

  Bioorganic & medicinal chemistry letters 20070301

• A new nitrate derivative of piperazine: its influence on platelet activity.

  Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070301

• Thyroid outcome during long-term gonadotropin-releasing hormone agonist treatments for idiopathic precocious puberty.

  The Journal of adolescent health : official publication of the Society for Adolescent Medicine 20070301

• Enzymatic synthesis of dehydroderivatives from proline-containing cyclic dipeptides and their effects toward cell division.

  Bioscience, biotechnology, and biochemistry 20070301

• Finger pain in rock climbers: reaching the right differential diagnosis and therapy.

  The Journal of sports medicine and physical fitness 20070301

• 'Two-point' assembling of Zn(II) and Co(II) metalloporphyrins derivatized with a crown ether substituent in Langmuir and Langmuir-Blodgett films.

  Langmuir : the ACS journal of surfaces and colloids 20070227

• Development and validation of chemometrics-assisted spectrophotometric and liquid chromatographic methods for the simultaneous determination of two multicomponent mixtures containing bronchodilator drugs.

  Journal of pharmaceutical and biomedical analysis 20070219

• Synthesis and antimalarial evaluation of a series of piperazinyl flavones.

  Bioorganic & medicinal chemistry letters 20070215

• A simple class of photorheological fluids: surfactant solutions with viscosity tunable by light.

  Journal of the American Chemical Society 20070214

• CVT-4325 inhibits myocardial fatty acid uptake and improves left ventricular systolic function without increasing myocardial oxygen consumption in dogs with chronic heart failure.

  Cardiovascular drugs and therapy 20070201

• Enrichment of functional redox reactive proteins and identification by mass spectrometry results in several terminal Fe(III)-reducing candidate proteins in Shewanella oneidensis MR-1.

  Journal of microbiological methods 20070201

• Analysis of structures with saturated hydrogen bonding.

  Acta crystallographica. Section B, Structural science 20070201

• Second lumbrical muscle recordings improve localization in severe carpal tunnel syndrome.

  Archives of physical medicine and rehabilitation 20070201

• Similar outcome for cryopreserved embryo transfer following GnRH-antagonist/GnRH-agonist, GnRH-antagonist/HCG or long protocol ovarian stimulation.

  Reproductive biomedicine online 20070201

• The effect of a GnRH agonist on cryopreserved human ovarian grafts in severe combined immunodeficient mice.

  Reproduction (Cambridge, England) 20070201

• Structure determination of new analogues of vardenafil and sildenafil in dietary supplements.

  Food additives and contaminants 20070201

• HEPES-stabilized encapsulation of Salmonella typhimurium.

  Langmuir : the ACS journal of surfaces and colloids 20070130

• Fluorescent CXCR4 chemokine receptor antagonists: metal activated binding.

  Chemical communications (Cambridge, England) 20070128

• Evaluation of methods for the determination of water in substances with unknown chemical and thermal behaviour.

  Journal of pharmaceutical and biomedical analysis 20070117

• DAT/SERT selectivity of flexible GBR 12909 analogs modeled using 3D-QSAR methods.

  Bioorganic & medicinal chemistry 20070115

• Adsorption of Acid Red 73 on copper dithiocarbamate precipitate-type solid wastes.

  Chemosphere 20070101

• Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin.

  Bioorganic & medicinal chemistry 20070101

• Dyspareunia and quality of sex life after laparoscopic excision of endometriosis and postoperative administration of triptorelin.

  Fertility and sterility 20070101

• Adsorption and oxidation of fluoroquinolone antibacterial agents and structurally related amines with goethite.

  Chemosphere 20070101

• New insights into the passive force enhancement in skeletal muscles.

  Journal of biomechanics 20070101

• Structure and medium effects on the photochemical behavior of nonfluorinated quinolone antibiotics.

  Photochemistry and photobiology 20070101

• Control of channel shapes in a microporous manganese(II)-borophosphate framework by variation of size and shape of organic template cations.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20070101

• Anti-androgenic treatment of obsessive-compulsive disorder: an open-label clinical trial of the long-acting gonadotropin-releasing hormone analogue triptorelin.

  International clinical psychopharmacology 20070101

• Synthesis and antibacterial activity of new 7-piperazinyl-quinolones containing a functionalized 2-(furan-3-yl)ethyl moiety.

  Archiv der Pharmazie 20070101

• Essential thrombocythemia.

  Orphanet journal of rare diseases 20070101

• Drug evaluation: PRX-00023, a selective 5-HT1A receptor agonist for depression.

  Current opinion in investigational drugs (London, England : 2000) 20070101

• [Side effects of treatment with the long-acting gonadorelin agonist triptorelin in a case of paraphilia].

  Tijdschrift voor psychiatrie 20070101

• Metabolism and excretion of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]-pyrimidin-4-one (SK3530) in rats.

  Rapid communications in mass spectrometry : RCM 20070101

• Importance of c-Type cytochromes for U(VI) reduction by Geobacter sulfurreducens.

  BMC microbiology 20070101

• Discovery of JANUVIA (Sitagliptin), a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes.

  Current topics in medicinal chemistry 20070101

• Differentiation of three pairs of positional isomers of hybrid peptides with repeats of phenylalanine-beta3-h-valine/beta3-valine-phenylalanine by electrospray ionization tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• A case of poly-parasitism involving a trematode and four different nematodes in a migrant from Bihar.

  Indian journal of medical microbiology 20070101

• The Genetic Basis of the Polycystic Ovary Syndrome: A Literature Review Including Discussion of PPAR-gamma.

  PPAR research 20070101

• Electromicroscopic observations on gliotoxin-induced apoptosis of cancer cells in culture and human cancer xenografts in transplanted SCID mice.

  In vivo (Athens, Greece) 20070101

• Chemistry and structural evaluation of different phospholipase A2 inhibitors in arachidonic acid pathway mediated inflammation and snake venom toxicity.

  Current topics in medicinal chemistry 20070101

• An acetal-based PEGylation reagent for pH-sensitive shielding of DNA polyplexes.

  Bioconjugate chemistry 20070101

• Parallel solution-phase synthesis of 4H-benzo[1,4]thiazin-3-one and 1,1-dioxo-1,4-dihydro-2H-1lambda6-benzo[1,4]thiazin-3-one derivatives from 1,5-difluoro-2,4-dinitrobenzene.

  Journal of combinatorial chemistry 20070101

• Trimetazidine administration minimizes myocardial damage and improves left ventricular function after percutaneous coronary intervention.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101

• [Synthesis and antibacterial activity of 3-(4-piperazin-1-yl-phenyl)-s-triazolo [3,4-b] [1,3,4] thiadiazole hydrochlorides].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070101

• Anti-calmodulins and tricyclic adjuvants in pain therapy block the TRPV1 channel.

  PloS one 20070101

• GnRH and LHR gene variants predict adverse outcome in premenopausal breast cancer patients.

  Breast cancer research : BCR 20070101

• Fluoroquinolone antibiotics in the environment.

  Reviews of environmental contamination and toxicology 20070101

• Targeted Gene Disruption of the Cyclo (L-Phe, L-Pro) Biosynthetic Pathway in Streptomyces sp. US24 Strain.

  Journal of biomedicine & biotechnology 20070101

• No supra-additive effects of goserelin and radiotherapy on clonogenic survival of prostate carcinoma cells in vitro.

  Radiation oncology (London, England) 20070101

• The vascular anatomy of the lumbrical muscles in the hand.

  Journal of plastic, reconstructive & aesthetic surgery : JPRAS 20070101

• Expression and regulation of CCL18 in synovial fluid neutrophils of patients with rheumatoid arthritis.

  Arthritis research & therapy 20070101

• Dynamic remodelling of synapses can occur in the absence of the parent cell body.

  BMC neuroscience 20070101

• Origin and distribution of epipolythiodioxopiperazine (ETP) gene clusters in filamentous ascomycetes.

  BMC evolutionary biology 20070101

• Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site.

  BMC structural biology 20070101

• Determination of long-acting release octreotide, an octapeptide analogue of somatostation, in human plasma by liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Lymphatic vessel density and function in experimental bladder cancer.

  BMC cancer 20070101

• A prospective, randomised, controlled clinical study on the assessment of tolerability and of clinical efficacy of Merional (hMG-IBSA) administered subcutaneously versus Merional administered intramuscularly in women undergoing multifollicular ovarian stimulation in an ART programme (IVF).

  Reproductive biology and endocrinology : RB&E 20070101

• Time course of effect of piperazine citrate on the electrocardiogram of the rat.

  American journal of therapeutics 20070101

• Adjuvant endocrine therapy for premenopausal women with early breast cancer.

  Breast cancer research : BCR 20070101

• Synthesis, spectroscopic, and antimicrobial studies of binuclear metallocene (M = Ti, Zr, or Hf) derivatives of bis(mercaptoazoles).

  Bioinorganic chemistry and applications 20070101

• NS-187 (INNO-406), a Bcr-Abl/Lyn dual tyrosine kinase inhibitor.

  Analytical chemistry insights 20070101

• Anthelmintic activity of leaves of justicia beddomei.

  Ancient science of life 20070101

• Metal-organic frameworks from zinc sulfite clusters, chains, and sheets: 4-connected, (3,4)-connected 3-D frameworks and 2-D arrays of catenane-like interlocking rings.

  Inorganic chemistry 20061225

• GliP, a multimodular nonribosomal peptide synthetase in Aspergillus fumigatus, makes the diketopiperazine scaffold of gliotoxin.

  Biochemistry 20061219

• What is the origin of the premotor potential recorded from the second lumbrical?

  Muscle & nerve 20061201

• Structure-activity relationships in platelet-activating factor. Part 13: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 or pure antiretroviral activity.

  Bioorganic & medicinal chemistry 20061201

• Structure-activity relationships in platelet-activating factor. Part 14: synthesis and biological evaluation of piperazine derivatives with dual anti-PAF and anti-HIV-1 activity.

  Bioorganic & medicinal chemistry 20061201

• Inhibitors of unactivated p38 MAP kinase.

  Bioorganic & medicinal chemistry letters 20061201

• Antihelminthic activity of some newly synthesized 5(6)-(un)substituted-1H-benzimidazol-2-ylthioacetylpiperazine derivatives.

  European journal of medicinal chemistry 20061201

• Estrogen receptor alpha regulates insulin sensitivity through IRS-1 tyrosine phosphorylation in mature 3T3-L1 adipocytes.

  Endocrine journal 20061201

• Bactericidal activity and target preference of a piperazinyl-cross-linked ciprofloxacin dimer with Staphylococcus aureus and Escherichia coli.

  The Journal of antimicrobial chemotherapy 20061201

• Two new dioxopiperazine derivatives, arestrictins A and B, isolated from Aspergillus restrictus and Aspergillus penicilloides.

  Chemical & pharmaceutical bulletin 20061201

• First total synthesis and biological screening of hymenamide E.

  Acta pharmaceutica (Zagreb, Croatia) 20061201

• Catalytic and stoichiometric approaches to the desymmetrisation of centrosymmetric piperazines by enantioselective acylation: a total synthesis of dragmacidin A.

  Organic & biomolecular chemistry 20061121

• Kinetic model for reactivity in quaternary water-in-oil microemulsions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20061106

• Clozapine, a neuroleptic agent, inhibits Akt by counteracting Ca2+/calmodulin in PTEN-negative U-87MG human glioblastoma cells.

  Cellular signalling 20061101

• The biological activity of the histidine-containing diketopiperazines cyclo(His-Ala) and cyclo(His-Gly).

  Peptides 20061101

• Physiological, biochemical, and genetic characterization of an alicyclic amine-degrading Mycobacterium sp. strain THO100 isolated from a morpholine-containing culture of activated sewage sludge.

  Archives of microbiology 20061101

• In vitro anthelmintic activity of Melia azedarach naturalized in Argentina.

  Phytotherapy research : PTR 20061101

• High-affinity binding and direct electron transfer to solid metals by the Shewanella oneidensis MR-1 outer membrane c-type cytochrome OmcA.

  Journal of the American Chemical Society 20061101

• [Triptorelin therapy in girls with central precocious puberty increases body mass index].

  Anales de pediatria (Barcelona, Spain : 2003) 20061101

• [Central precocious puberty is associated with a high prevalence of organic disease].

  Anales de pediatria (Barcelona, Spain : 2003) 20061101

• Structure-activity relationship of quinoline derivatives as potent and selective alpha(2C)-adrenoceptor antagonists.

  Journal of medicinal chemistry 20061019

• Construction of 3D layer-pillared homoligand coordination polymers from a 2D layered precursor.

  Inorganic chemistry 20061016

• The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase.

  Bioorganic & medicinal chemistry 20061001

• Conformational studies of proline-, thiaproline- and dimethylsilaproline-containing diketopiperazines.

  Journal of peptide science : an official publication of the European Peptide Society 20061001

• From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist.

  Bioorganic & medicinal chemistry letters 20061001

• Actions of gonadotropin-releasing hormone analogues in pituitary gonadotrophs and their modulation by ovarian steroids.

  The Journal of steroid biochemistry and molecular biology 20061001

• Beneficial effect of luteal-phase GnRH agonist administration on embryo implantation after ICSI in both GnRH agonist- and antagonist-treated ovarian stimulation cycles.

  Human reproduction (Oxford, England) 20061001

• Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy.

  Nature chemical biology 20061001

• Effect of piperazine (diethylenediamine) on the moulting, proteome expression and pyrophosphatase activity of Ascaris suum lung-stage larvae.

  Acta tropica 20061001

• Reproductive outcome in patients treated and not treated for idiopathic early puberty: long-term results of a randomized trial in adults.

  The Journal of pediatrics 20061001

• [Piperazines as model substrate for oxidations].

  Die Pharmazie 20061001

• Quantitative structure-activity relationship study of new potent and selective antagonists at the 5-HT(1A) and adrenergic alpha(1d) receptors: Derivatives of spiroethyl phenyl(substituted)piperazine.

  Journal of enzyme inhibition and medicinal chemistry 20061001

• [Effect of triptorelin and an extended-interval dosing regimen in the treatment of patients with endometriosis and adenomyoma].

  Zhonghua fu chan ke za zhi 20061001

• Isolated neuropathy of the recurrent motor branch of the median nerve.

  Neurosciences (Riyadh, Saudi Arabia) 20061001

• Evolution of the structural chemistry of vanadium organodiphosphonate networks and frameworks: structural consequences of fluoride incorporation in the development of stable phases with void channels.

  Inorganic chemistry 20060918

• Propionylpiperazines as human melanocortin-4 receptor ligands.

  Bioorganic & medicinal chemistry letters 20060915

• Pharmacological characterization of novel water-soluble cannabinoids.

  The Journal of pharmacology and experimental therapeutics 20060901

• Arylpropionylpiperazines as antagonists of the human melanocortin-4 receptor.

  Bioorganic & medicinal chemistry letters 20060901

• Antifouling activity of synthesized peptide analogs of the sponge metabolite barettin.

  Peptides 20060901

• Asymmetric synthesis of 1-(2- and 3-haloalkyl)azetidin-2-ones as precursors for novel piperazine, morpholine, and 1,4-diazepane annulated beta-lactams.

  The Journal of organic chemistry 20060901

• Rapid screening for and simultaneous semiquantitative analysis of thirty abused drugs in human urine samples using gas chromatography-mass spectrometry.

  Journal of analytical toxicology 20060901

• Comparative study on the regeneration of flue-gas desulfurizing agents by using conventional electrodialysis (ED) and bipolar membrane electrodialysis (BMED).

  Environmental science & technology 20060901

• Structure-activity studies on the protection of Trimetazidine derivatives modified with nitroxides and their precursors from myocardial ischemia-reperfusion injury.

  Bioorganic & medicinal chemistry 20060815

• N-(1,2-diphenylethyl)piperazines: a new class of dual serotonin/noradrenaline reuptake inhibitor.

  Bioorganic & medicinal chemistry letters 20060815

• Structure-activity relationships of N-substituted piperazine amine reuptake inhibitors.

  Bioorganic & medicinal chemistry letters 20060815

• Straightforward access to pyrazines, piperazinones, and quinoxalines by reactions of 1,2-diaza-1,3-butadienes with 1,2-diamines under solution, solvent-free, or solid-phase conditions.

  The Journal of organic chemistry 20060804

• Depsipeptide methodology for solid-phase peptide synthesis: circumventing side reactions and development of an automated technique via depsidipeptide units.

  The Journal of organic chemistry 20060804

• The synthesis and anti-proliferative effects of beta-elemene derivatives with mTOR inhibition activity.

  Bioorganic & medicinal chemistry 20060801

• Complete hormonal blockade versus epirubicin-based chemotherapy in premenopausal, one to three node-positive, and hormone-receptor positive, early breast cancer patients: 7-year follow-up results of French Adjuvant Study Group 06 randomised trial.

  Annals of oncology : official journal of the European Society for Medical Oncology 20060801

• Anti-plasmodial and anti-leishmanial activity of conformationally restricted pentamidine congeners.

  The Journal of pharmacy and pharmacology 20060801

• c-Type cytochrome-dependent formation of U(IV) nanoparticles by Shewanella oneidensis.

  PLoS biology 20060801

• Treatment of central precocious puberty with triptorelin 11.25 mg depot formulation.

  Journal of pediatric endocrinology & metabolism : JPEM 20060801

• [The SERS of glycine anhydride on positive silver colloids].

  Guang pu xue yu guang pu fen xi = Guang pu 20060801

• Regulation of GnRH I receptor gene expression by the GnRH agonist triptorelin, estradiol, and progesterone in the gonadotroph-derived cell line alphaT3-1.

  Endocrine 20060801

• Cultivating bacteria's taste for toxic waste.

  PLoS biology 20060801

• Gene delivery by aminofullerenes: structural requirements for efficient transfection.

  Chemistry, an Asian journal 20060717

• Naphthyl and coumarinyl biarylpiperazine derivatives as highly potent human beta-secretase inhibitors. Design, synthesis, and enzymatic BACE-1 and cell assays.

  Journal of medicinal chemistry 20060713

• Antitumor activity of JS-K [O2-(2,4-dinitrophenyl) 1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate] and related O2-aryl diazeniumdiolates in vitro and in vivo.

  Journal of medicinal chemistry 20060713

• Syntheses, crystal structures and antimicrobial activities of 6-coordinate antimony(III) complexes with tridentate 2-acetylpyridine thiosemicarbazone, bis(thiosemicarbazone) and semicarbazone ligands.

  Journal of inorganic biochemistry 20060701

• Synthesis and antibacterial activity of new fluoroquinolones containing a substituted N-(phenethyl)piperazine moiety.

  Bioorganic & medicinal chemistry letters 20060701

• The sigma-2 receptor agonist PB28 inhibits calcium release from the endoplasmic reticulum of SK-N-SH neuroblastoma cells.

  Cell calcium 20060701

• Antibacterial evaluation of a collection of norfloxacin and ciprofloxacin derivatives against multiresistant bacteria.

  International journal of antimicrobial agents 20060701

• In vitro selection and in vivo efficacy of piperazine- and alkanediamide-linked bisbenzamidines against Pneumocystis pneumonia in mice.

  Antimicrobial agents and chemotherapy 20060701

• Complications after treatment of flexor tendon injuries.

  The Journal of the American Academy of Orthopaedic Surgeons 20060701

• Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.

  Journal of medicinal chemistry 20060615

• Patterns of metabolites produced from the fluoroquinolone enrofloxacin by basidiomycetes indigenous to agricultural sites.

  Applied microbiology and biotechnology 20060601

• Molecular dynamics of the Shewanella oneidensis response to chromate stress.

  Molecular & cellular proteomics : MCP 20060601

• Dynamic lumbrical muscle transfer for correction of posttraumatic extensor tendon subluxation.

  Techniques in hand & upper extremity surgery 20060601

• [Tendinous sheath fibroma causing 'trigger wrist' and carpal tunnel syndrome].

  Chirurgie de la main 20060601

• Combination growth hormone and gonadotropin releasing hormone analog therapy in 11beta-hydroxylase deficiency.

  Journal of pediatric endocrinology & metabolism : JPEM 20060601

• Axial coordination changes the morphology of porphyrin assemblies in an organogel system.

  Organic & biomolecular chemistry 20060521

• Synthesis of new and potent analogues of anti-tuberculosis agent 5-nitro-furan-2-carboxylic acid 4-(4-benzyl-piperazin-1-yl)-benzylamide with improved bioavailability.

  Bioorganic & medicinal chemistry letters 20060515

• Pituitary desensitization for eight weeks after the administration of two distinct gonadotrophin-releasing hormone agonists.

  European journal of obstetrics, gynecology, and reproductive biology 20060501

• Safety and efficacy of low dose hCG for luteal support after triggering ovulation with a GnRH agonist in cases of polyfollicular development.

  European journal of obstetrics, gynecology, and reproductive biology 20060501

• 4-Amino derivatives of the Hsp90 inhibitor CCT018159.

  Bioorganic & medicinal chemistry letters 20060501

• Solid-phase S-3CR generates N-substituted alpha-aminonitriles for the synthesis of alpha-phenyl-alpha-(1-piperazinyl) substituted amino acids.

  Amino acids 20060501

• Pediatric cinnarizine overdose and toxicokinetics.

  Pediatrics 20060501

• Structural diversity of the oxovanadium organodiphosphonate system: a platform for the design of void channels.

  Inorganic chemistry 20060417

• Singular value decomposition of torsional angles of analogs of the dopamine reuptake inhibitor GBR 12909.

  Journal of computational chemistry 20060415

• Tricyclic pharmacophore-based molecules as novel integrin alpha(v)beta3 antagonists. Part 1: design and synthesis of a lead compound exhibiting alpha(v)beta3/alpha(IIb)beta3 dual antagonistic activity.

  Bioorganic & medicinal chemistry 20060401

• Susceptibility studies of piperazinyl-cross-linked fluoroquinolone dimers against test strains of Gram-positive and Gram-negative bacteria.

  Diagnostic microbiology and infectious disease 20060401

• Synthesis and biological evaluation of heteroaryldiamides and heteroaryldiamines as cytotoxic agents, apoptosis inducers and caspase-3 activators.

  Archiv der Pharmazie 20060401

• Synthesis and in vitro evaluation of iodinated derivatives of piperazine as a new ligand for sigma receptor imaging by single photon emission computed tomography.

  Chemical & pharmaceutical bulletin 20060401

• Clinical efficacy of body mass index as predictor of in vitro fertilization and embryo transfer outcomes.

  Journal of Korean medical science 20060401

• Metabolites from the marine-derived fungus Chromocleista sp. isolated from a deep-water sediment sample collected in the Gulf of Mexico.

  Journal of natural products 20060401

• Hierarchical clustering analysis of flexible GBR 12909 dialkyl piperazine and piperidine analogs.

  Journal of computer-aided molecular design 20060401

• [Synthesis and bioactivity of substituted alpha-aminobenzylphosphonate].

  Yao xue xue bao = Acta pharmaceutica Sinica 20060401

• Determination of piperazine in pharmaceutical drug substances using capillary electrophoresis with indirect UV detection.

  Journal of chromatography. A 20060331

• Synthesis and antimicrobial activity of N-alkyl and N-aryl piperazine derivatives.

  Bioorganic & medicinal chemistry 20060315

• Novel 4-N-substituted aryl pent-2-ene-1,4-dione derivatives of piperazinyloxazolidinones as antibacterials.

  Bioorganic & medicinal chemistry letters 20060315

• Role of excited state intramolecular charge transfer in the photophysical properties of norfloxacin and its derivatives.

  The journal of physical chemistry. A 20060302

• Endocrine, morphological, and cytological effects of a depot GnRH agonist in bovine.

  Animal reproduction science 20060301

• Serum and follicular fluid levels of soluble Fas and soluble Fas ligand in IVF cycles.

  European journal of obstetrics, gynecology, and reproductive biology 20060301

• Spontaneous remission of acute myeloid leukemia associated with GnRH agonist treatment.

  Leukemia & lymphoma 20060301

• Synthesis and receptor binding studies of 3-substituted piperazine derivatives.

  European journal of medicinal chemistry 20060301

• First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats.

  Environmental health perspectives 20060301

• Effects of amino acid chirality and the chemical linker on the cell permeation characteristics of cyclic prodrugs of opioid peptides.

  Journal of medicinal chemistry 20060223

• CB694, a novel antimitotic with antitumor activities.

  International journal of cancer 20060215

• Oxidation of Good's buffers by hydrogen peroxide.

  Analytical biochemistry 20060215

• Piperazinyl oxime ethers as NK-1 receptor antagonists.

  Bioorganic & medicinal chemistry letters 20060215

• Enhanced FTase activity achieved via piperazine interaction with catalytic zinc.

  Bioorganic & medicinal chemistry letters 20060215

• Coordination frameworks constructed from bipyridyl piperazine and MCl2 (M = Co, Ni, Zn): structural characterization and optical properties.

  Dalton transactions (Cambridge, England : 2003) 20060214

• Novel water-soluble quaternary piperazine derivatives of chitosan: synthesis and characterization.

  Macromolecular bioscience 20060210

• Inhibition of human experimental prostate cancers by a targeted cytotoxic luteinizing hormone-releasing hormone analog AN-207.

  The Prostate 20060201

• In silico design and synthesis of piperazine-1-pyrrolidine-2,5-dione scaffold-based novel malic enzyme inhibitors.

  Bioorganic & medicinal chemistry letters 20060201

• Optimal recording electrode placement in the lumbrical-interossei comparison study.

  Muscle & nerve 20060201

• NMR study on cis-N-[4-[4-(1,2-benzisozole-3-yl)-1-piperazinyl] butyl]cyclohexane-1,2-dicarboximide monohydrochloride dihydrate.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060201

• Griseofulvin and ketoconazole solubilization by bile salts studied using fluorescence spectroscopy.

  Colloids and surfaces. B, Biointerfaces 20060201

• Hydrogen bonding and pi-pi stacking in 7-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethoxy}-4-methyl-2H-chromen-2-one monohydrate.

  Acta crystallographica. Section C, Crystal structure communications 20060201

• Levels of apoptosis in human granulosa cells seem to be comparable after therapy with a gonadotropin-releasing hormone agonist or antagonist.

  Fertility and sterility 20060201

• Administration of alternate day triptorelin for controlled ovarian hyperstimulation is cost effective.

  Fertility and sterility 20060201

• Unique asymmetric (CuII4) double-stranded helicate from a hexadentate piperazine-based ligand: ligand conformation isomerism upon coordination.

  Inorganic chemistry 20060123

• DNA binding potential and cytotoxicity of newly designed pyrrolobenzodiazepine dimers linked through a piperazine side-armed-alkane spacer.

  Bioorganic & medicinal chemistry 20060115

• Synthesis and in vivo validation of [O-methyl-11C]2-{4-[4-(7-methoxynaphthalen-1-yl)piperazin- 1-yl]butyl}-4-methyl-2H-[1,2,4]triazine-3,5-dione: a novel 5-HT1A receptor agonist positron emission tomography ligand.

  Journal of medicinal chemistry 20060112

• Estimation of finger muscle tendon tensions and pulley forces during specific sport-climbing grip techniques.

  Journal of biomechanics 20060101

• Investigation of gas phase ion structure for proline-containing b(2) ion.

  Journal of the American Society for Mass Spectrometry 20060101

• Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase.

  Nature medicine 20060101

• Three-month sustained-release triptorelin (11.25 mg) in the treatment of central precocious puberty.

  European journal of endocrinology 20060101

• Electrocardiographic profile of oral piperazine citrate in healthy volunteers.

  American journal of therapeutics 20060101

• BLAST screening of chlamydial genomes to identify signature proteins that are unique for the Chlamydiales, Chlamydiaceae, Chlamydophila and Chlamydia groups of species.

  BMC genomics 20060101

• Ranolazine: a review of its use in chronic stable angina pectoris.

  Drugs 20060101

• Occupational asthma due to piperazine citrate.

  Journal of investigational allergology & clinical immunology 20060101

• Clinically useful vanilloid receptor TRPV1 antagonists: just around the corner (or too early to tell)?

  Progress in medicinal chemistry 20060101

• New cathepsin d inhibitors with hydroxyethylamine isosteres: preparation and characterization.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20060101

• Discovery and development of pyrazole-scaffold Hsp90 inhibitors.

  Current topics in medicinal chemistry 20060101

• The melanocortin system as a therapeutic treatment target for adiposity and adiposopathy.

  Drugs in R&D 20060101

• Spotlight on ranolazine in chronic stable angina pectoris.

  American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101

• Linker chain effect of ferrocenylnaphthalene diimide derivatives on a tetraplex DNA binding.

  Nucleic acids symposium series (2004) 20060101

• Gastric mucosal damage following repeat administration of melanocortin subtype-4 receptor ligands to Fischer 344 rats.

  Toxicologic pathology 20060101

• Effect of iron on the expression of sirR and sitABC in biofilm-associated Staphylococcus epidermidis.

  BMC microbiology 20060101

• A comparative study on the cost of new antibiotics and drugs of other therapeutic categories.

  PloS one 20060101

• Establishing improved normal values for nerve conduction studies.

  Journal of long-term effects of medical implants 20060101

• Establishing normal nerve conduction values- lumbrical and interosseous responses.

  Journal of long-term effects of medical implants 20060101

• Efficacy of subcutaneous administration of gonadotropin-releasing hormone agonist on idiopathic central precocious puberty.

  Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20060101

• Synthesis of some n-substituted derivatives of 1-(1h-pyrrole-1 -ylmethyl)- 10-oxa-4-azatricyclo [5.2.1.0(2,6)]dec-8-ene-3,5-dione with an expected anxiolytic activity.

  Acta poloniae pharmaceutica 20060101

• Letter: electron ionization-induced fragmentation of new thiochalcone derivatives.

  European journal of mass spectrometry (Chichester, England) 20060101

• Metal specificity of an iron-responsive element in Alzheimer's APP mRNA 5'untranslated region, tolerance of SH-SY5Y and H4 neural cells to desferrioxamine, clioquinol, VK-28, and a piperazine chelator.

  Journal of neural transmission. Supplementum 20060101

• EVALUATION OF ANTHELMINTIC ACTIVITIES OF AERIAL PARTS of Celsia coromandeliane Vahl AND Mollugo pentaphylla Linn.

  Ancient science of life 20060101

• Anthelmintic activity of aerial parts of melothria heterophylla lour.

  Ancient science of life 20060101

• Surfing the piperazine core of tricyclic farnesyltransferase inhibitors.

  Bioorganic & medicinal chemistry letters 20051215

• Synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 1. Synthesis and antimicrobial activity of (benzofuran-2-yl)(3-phenyl-3-methylcyclobutyl) ketoxime derivatives.

  European journal of medicinal chemistry 20051201

• Researching the toxicity of party pills.

  Nursing New Zealand (Wellington, N.Z. : 1995) 20051201

• Privileged structure based ligands for melanocortin receptors--substituted benzylic piperazine derivatives.

  Bioorganic & medicinal chemistry letters 20051115

• Relationship between force and stiffness in muscle fibers after stretch.

  Journal of applied physiology (Bethesda, Md. : 1985) 20051101

• Cetirizine dihydrochloride interaction with some diclofenac complexes.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20051101

• Benzyl ether structure-activity relationships in a series of ketopiperazine-based renin inhibitors.

  Bioorganic & medicinal chemistry letters 20051101

• In vitro antiparasitic activity of extracts of Cardiospermum halicacabum against third-stage larvae of Strongyloides stercoralis.

  Parasitology research 20051101

• Identification of a potent and selective 5-HT1B receptor antagonist.

  Bioorganic & medicinal chemistry letters 20051101

• Structural characterization and DNA interactions of new cytotoxic transplatin analogues containing one planar and one nonplanar heterocyclic amine ligand.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20051101

• Roquefortine E, a diketopiperazine from an Australian isolate of Gymnoascus reessii.

  Journal of natural products 20051101

• Analysis of intrinsic-extrinsic muscle function through interactive 3-dimensional kinematic simulation and cadaver studies.

  The Journal of hand surgery 20051101

• A lower ongoing pregnancy rate can be expected when GnRH agonist is used for triggering final oocyte maturation instead of HCG in patients undergoing IVF with GnRH antagonists.

  Human reproduction (Oxford, England) 20051001

• Synthesis and SAR of novel oxazolidinones: discovery of ranbezolid.

  Bioorganic & medicinal chemistry letters 20051001

• Chiral separation and CD characterisation of enantiomeric cyclotriphosphazene derivatives.

  Chirality 20051001

• Transdermal iontophoretic delivery of triptorelin in vitro.

  Journal of pharmaceutical sciences 20051001

• MRI of the intrinsic muscles of the hand: spectrum of imaging findings and clinical correlation.

  AJR. American journal of roentgenology 20051001

• GnRH-II receptor-like antigenicity in human placenta and in cancers of the human reproductive organs.

  European journal of endocrinology 20051001

• Analogs of GnRH-I and GnRH-II inhibit epidermal growth factor-induced signal transduction and resensitize resistant human breast cancer cells to 4OH-tamoxifen.

  European journal of endocrinology 20051001

• [Pharmacokinetics and pharmacodynamics of triptorelin].

  Annales d'urologie 20051001

• [Treatment of precocious puberty by GnRH agonists].

  Annales d'urologie 20051001

• A preliminary study on reduced dose (33 or 25 microg) gonadotropin-releasing hormone agonist long protocol for multifollicular ovarian stimulation in patients with high basal serum follicle-stimulating hormone levels undergoing in vitro fertilization-embryo transfer.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20051001

• A facile synthesis of novel herbicidal 1-phenyl-piperazine-2,6-diones.

  Molecules (Basel, Switzerland) 20050930

• An LC-MS-MS method for the determination of cyclizine in human serum.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925

• Modulation of passive force in single skeletal muscle fibres.

  Biology letters 20050922

• Phase II trial of tamoxifen and goserelin in recurrent epithelial ovarian cancer.

  British journal of cancer 20050919

• Interactions of fluoroquinolone antibacterial agents with aqueous chlorine: reaction kinetics, mechanisms, and transformation pathways.

  Environmental science & technology 20050915

• Design and synthesis of a thermally stable organic electride.

  Journal of the American Chemical Society 20050907

• Neuroprotective effects of novel small peptides in vitro and after brain injury.

  Neuropharmacology 20050901

• Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma.

  Bioorganic & medicinal chemistry letters 20050901

• Different effects of agonistic vs. antagonistic gnrh-analogues (triptorelin vs. cetrorelix) on bone modeling and remodeling in peripubertal female rats.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050901

• Prolactin secretion before, during, and after chronic gonadotropin-releasing hormone agonist treatments in children.

  Fertility and sterility 20050901

• A new fluorescent assay for enalapril maleate.

  Journal of fluorescence 20050901

• Structural Investigation of bis(4-methyl-1-piperazineglyoximato)dipyridinato cobalt(III) chloro dinitrate trihydrate.

  Molecules (Basel, Switzerland) 20050831

• Short-term and long-term results of resectoscopic myomectomy with and without pretreatment with GnRH analogs in premenopausal women.

  Acta obstetricia et gynecologica Scandinavica 20050801

• Structure of radical cations of saturated heterocyclic compounds with two heteroatoms as studied by electron paramagnetic resonance, electron-nuclear double resonance, and density functional theory calculations.

  The journal of physical chemistry. A 20050721

• Microheterogeneous solvation for aminolysis reactions in AOT-based water-in-oil microemulsions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050718

• The impact of natural helminth infections and supplementary protein on growth performance of free-range chickens on smallholder farms in El Sauce, Nicaragua.

  Preventive veterinary medicine 20050712

• Design, synthesis, and biological testing of thiosalicylamides as a novel class of calcium channel blockers.

  Bioorganic & medicinal chemistry 20050701

• [Clinical trial on the effectiveness and safety of triptorelin in treatment of uterine leiomyoma].

  Zhonghua fu chan ke za zhi 20050701

• Effect of heterocyclic based organoclays on the properties of polyimide-clay nanocomposites.

  Journal of nanoscience and nanotechnology 20050701

• Ramification pattern of the deep branch of the lateral plantar nerve in the human foot.

  Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20050701

• Oxidative transformation of fluoroquinolone antibacterial agents and structurally related amines by manganese oxide.

  Environmental science & technology 20050615

• Design, synthesis, and evaluation of proline based melanocortin receptor ligands.

  Bioorganic & medicinal chemistry letters 20050602

• Relationship between intracellular PO2 recovery kinetics and fatigability in isolated single frog myocytes.

  Journal of applied physiology (Bethesda, Md. : 1985) 20050601

• GnRH agonist versus GnRH antagonist in oocyte donation cycles: a prospective randomized study.

  Human reproduction (Oxford, England) 20050601

• Anti-angiogenic and anti-tumor apoptotic activities of a topoisomerase II inhibiting agent SJ-8026.

  International journal of oncology 20050601

• Reciprocal mutations in TM2/TM3 in a D2 dopamine receptor background confirms the importance of this microdomain as a selective determinant of para-halogenated 1,4-disubstituted aromatic piperazines.

  Archiv der Pharmazie 20050601

• Prediction of genotoxicity of chemical compounds by statistical learning methods.

  Chemical research in toxicology 20050601

• Unique diketopiperazine dimers from the insect pathogenic fungus Verticillium hemipterigenum BCC 1449.

  Organic letters 20050526

• Modification and structure-activity relationship of a small molecule HIV-1 inhibitor targeting the viral envelope glycoprotein gp120.

  Organic & biomolecular chemistry 20050507

• Low-temperature 1H and 13C NMR spectra of N-substituted 1,2,3,4-tetrahydropyrazino[1,2-a]indoles.

  Magnetic resonance in chemistry : MRC 20050501

• First insights into regiospecific transnitrosation reactions between tryptophan derivatives: melatonin as an effective target.

  Journal of pineal research 20050501

• Synthesis, dopamine D2 receptor binding studies and docking analysis of 5-[3-(4-arylpiperazin-1-yl)propyl]-1H-benzimidazole, 5-[2-(4-arylpiperazin-1-yl)ethoxy]-1H-benzimidazole and their analogs.

  European journal of medicinal chemistry 20050501

• Recombinant gonadotrophin-based, ovarian hyperstimulation syndrome-free stimulation of the high responder: suggested protocol for further research.

  Reproductive biomedicine online 20050501

• Effect of unilateral damage to sciatic nerve on phenotype of lumbrical muscles in experimental and contralateral legs in rats.

  Bulletin of experimental biology and medicine 20050501

• Sequence-specific binding of m-phenylene ethynylene foldamers to a piperazinium dihydrochloride salt.

  Organic letters 20050428

• Enantioselective synthesis of stephacidin B.

  Journal of the American Chemical Society 20050420

• Piperazine additions to C60--a facile approach to fullerene substitution.

  Organic & biomolecular chemistry 20050407

• Synthesis and structure-activity relationships of a new model of arylpiperazines. 8. Computational simulation of ligand-receptor interaction of 5-HT(1A)R agonists with selectivity over alpha1-adrenoceptors.

  Journal of medicinal chemistry 20050407

• Cytochrome P450 3A-mediated metabolism of buspirone in human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20050401

• Novel fluoroquinolones: design, synthesis, and in vivo activity in mice against Mycobacterium tuberculosis H37Rv.

  Bioorganic & medicinal chemistry letters 20050401

• Drug-drug interaction between diclofenac, cetirizine and ranitidine.

  Journal of pharmaceutical and biomedical analysis 20050401

• Benzenesulfonamide analogs of fluoroquinolones. Antibacterial activity and QSAR studies.

  European journal of medicinal chemistry 20050401

• Early cessation of triptorelin in in vitro fertilization: a double-blind, randomized study.

  Fertility and sterility 20050401

• Progressive loss of motor neuron function in wasted mice: effects of a spontaneous null mutation in the gene for the eEF1 A2 translation factor.

  Journal of neuropathology and experimental neurology 20050401

• Docking of 6-chloropyridazin-3-yl derivatives active on nicotinic acetylcholine receptors into molluscan acetylcholine binding protein (AChBP).

  Farmaco (Societa chimica italiana : 1989) 20050401

• Serum luteinizing hormone, follicle-stimulating hormone and oestradiol pattern in women undergoing pituitary suppression with different gonadotrophin-releasing hormone analogue protocols for assisted reproduction.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20050401

• [Fluorescence spectra and protonation of ofloxacin].

  Guang pu xue yu guang pu fen xi = Guang pu 20050401

• Design, synthesis, and biological evaluation of new territrem B analogues.

  Chemistry & biodiversity 20050401

• Novel diamino derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.

  Journal of medicinal chemistry 20050324

• 3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance.

  Bioorganic & medicinal chemistry 20050315

• Melanocortin subtype-4 receptor agonists containing a piperazine core with substituted aryl sulfonamides.

  Bioorganic & medicinal chemistry letters 20050315

• Identification of a 5-HT4 receptor antagonist clinical candidate through side-chain modification.

  Bioorganic & medicinal chemistry letters 20050315

• First reaction of a bare silicon surface with acid chlorides and a one-step preparation of acid chloride terminated monolayers on scribed silicon.

  Langmuir : the ACS journal of surfaces and colloids 20050315

• Force enhancement and relaxation rates after stretch of activated muscle fibres.

  Proceedings. Biological sciences 20050307

• N-substituted piperazines abused by humans mimic the molecular mechanism of 3,4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy').

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050301

• Nuclear magnetic resonance investigation of the interaction of water vapor with sildenafil citrate in the solid state.

  Journal of pharmaceutical sciences 20050301

• Randomized trial of adjuvant ovarian suppression in 926 premenopausal patients with early breast cancer treated with adjuvant chemotherapy.

  Annals of oncology : official journal of the European Society for Medical Oncology 20050301

• Sorption of the antibiotic ofloxacin to mesoporous and nonporous alumina and silica.

  Journal of colloid and interface science 20050301

• Water soluble cationic trans-platinum complexes which induce programmed cell death in the protozoan parasite Leishmania infantum.

  Journal of inorganic biochemistry 20050301

• Benzothiophenes containing a piperazine side chain as selective ligands for the estrogen receptor alpha and their bioactivities in vivo.

  Bioorganic & medicinal chemistry letters 20050301

• Effect of halving the daily dose of triptorelin at the start of ovarian stimulation on hormone serum levels and the outcome of in vitro fertilization.

  Fertility and sterility 20050301

• Cyclo(L-leucyl-alpha,beta-dehydrophenylalanine): the first diketopiperazine containing an alpha,beta-dehydrophenylalanine residue.

  Acta crystallographica. Section C, Crystal structure communications 20050301

• Simultaneous separation of different types of amphetamine and piperazine designer drugs by capillary electrophoresis with a chiral selector.

  Journal of forensic sciences 20050301

• 5-(2-aminoethyl)dibenzo[c,h][1,6]naphthyridin-6-ones: variation of n-alkyl substituents modulates sensitivity to efflux transporters associated with multidrug resistance.

  Journal of medicinal chemistry 20050210

• Novel heterocyclic trans olefin analogues of N-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl}arylcarboxamides as selective probes with high affinity for the dopamine D3 receptor.

  Journal of medicinal chemistry 20050210

• Less symmetrical dicopper(II) complexes as catechol oxidase models--an adjacent thioether group increases catecholase activity.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20050204

• Cyp2D6 catalyzes 5-hydroxylation of 1-(2-pyrimidinyl)-piperazine, an active metabolite of several psychoactive drugs, in human liver microsomes.

  Drug metabolism and disposition: the biological fate of chemicals 20050201

• NMR study on (+/-)-1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6-dimethylphenyl)aminocarbonylmethyl]piperazine dihydrochloride salt.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050201

• IR, MS studies on (+/-)-1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6-dimethylphenyl)aminocarbonylmethyl]piperazine dihydrochloride salt.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050201

• Formation of quinol co-crystals with hydrogen-bond acceptors.

  Acta crystallographica. Section B, Structural science 20050201

• Biarylcarboxybenzamide derivatives as potent vanilloid receptor (VR1) antagonistic ligands.

  Bioorganic & medicinal chemistry letters 20050201

• Identification of agonists and antagonists of the human melanocortin-4 receptor from piperazinebenzylamines.

  Bioorganic & medicinal chemistry letters 20050201

• New antiproliferative benzoindolinothiazepines derivatives.

  European journal of medicinal chemistry 20050201

• Evaluation of two doses of recombinant luteinizing hormone supplementation in an unselected group of women undergoing follicular stimulation for in vitro fertilization.

  Fertility and sterility 20050201

• Metabolic activation of a 1,3-disubstituted piperazine derivative: evidence for a novel ring contraction to an imidazoline.

  Chemical research in toxicology 20050201

• In-vivo effects of the 1,2,4-piperazine derivatives MM5 and MC1, putative 5-HT agonists, on dopamine and serotonin release in rat prefrontal cortex.

  The Journal of pharmacy and pharmacology 20050201

• [Treatment of central precocious puberty with Gonadotropin-Releasing Hormone agonist (triptorelin) in girls: breast development, skeletal maturation, height and weight evolution during and after treatment].

  Revue medicale de Bruxelles 20050201

• [Metabolic pathways of dipfluzine in rats].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050201

• Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity.

  The Journal of organic chemistry 20050121

• Carbonic anhydrase inhibitors. Novel sulfanilamide/acetazolamide derivatives obtained by the tail approach and their interaction with the cytosolic isozymes I and II, and the tumor-associated isozyme IX.

  Bioorganic & medicinal chemistry letters 20050117

• Synthesis and structure-activity relationships of 1-aralkyl-4-benzylpiperidine and 1-aralkyl-4-benzylpiperazine derivatives as potent sigma ligands.

  Journal of medicinal chemistry 20050113

• Synthesis and thermal denaturation studies of novel 2'-O,3'-C-linked bicyclic oligonucleotides with a methoxy or a piperazino group facing the major groove of nucleic acid duplexes.

  Organic & biomolecular chemistry 20050107

• Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands.

  Bioorganic & medicinal chemistry 20050103

• Follicular fluid levels of vascular endothelial growth factor and leptin are associated with pregnancy outcome of normal women participating in intracytoplasmic sperm injection cycles.

  Physiological research 20050101

• [High throughput screening of pharmacokinetics and metabolism in drug discovery (II)--investigation on in vitro and in vivo correlation in drug metabolism screening].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050101

• Clinical results in severe carpal tunnel syndrome and motor nerve conduction studies.

  Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20050101

• Surface expression, single-channel analysis and membrane topology of recombinant Chlamydia trachomatis Major Outer Membrane Protein.

  BMC microbiology 20050101

• Phthalocyanines as an alternative to soluble polymer-supported platforms in organic synthesis.

  Molecular diversity 20050101

• Interaction of arylpiperazines with the dopamine receptor D2 binding site.

  Arzneimittel-Forschung 20050101

• [Pharmacodynamics of triptorelin].

  La Revue du praticien 20050101

• Multiple tandem mass spectrometry-based investigation of the behaviour of some thiazol-benzimidazolones and 2-benzimidazolylsulfanyl ethanones.

  European journal of mass spectrometry (Chichester, England) 20050101

• Sentinel node biopsy as an adjunct to limb salvage surgery for epithelioid sarcoma of the hand.

  World journal of surgical oncology 20050101

• Exocellular peptides from Antarctic psychrophile Pseudoalteromonas Haloplanktis.

  Marine biotechnology (New York, N.Y.) 20050101

• Antagonistic and agonistic GnRH analogue treatment of precocious puberty: tracking gonadotropin concentrations in urine.

  Hormone research 20050101

• A novel Geobacteraceae-specific outer membrane protein J (OmpJ) is essential for electron transport to Fe(III) and Mn(IV) oxides in Geobacter sulfurreducens.

  BMC microbiology 20050101

• Pharmacokinetics of theophylline after administration of suppositories formulation.

  Journal of immunoassay & immunochemistry 20050101

• Chronic angina: new medical options for treatment.

  Reviews in cardiovascular medicine 20050101

• ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversal.

  Cancer cell international 20050101

• The role of aromatase inhibitors in ameliorating deleterious effects of ovarian stimulation on outcome of infertility treatment.

  Reproductive biology and endocrinology : RB&E 20050101

• Clinical trial update: International Breast Cancer Study Group.

  Breast cancer research : BCR 20050101

• Clinical benefit of metaphase I oocytes.

  Reproductive biology and endocrinology : RB&E 20050101

• Laparoscopic myomectomy for very large myomas using an isobaric (gasless) technique.

  JSLS : Journal of the Society of Laparoendoscopic Surgeons 20050101

• Study on organic nitrates, part VIII. Pharmacological activity and nitric oxide generation capacity of nitrate derivatives of piperazine.

  Pharmacological reports : PR 20050101

• Hydrogen bonding patterns in the cocrystals of 5-nitrouracil with several donor and acceptor molecules.

  Beilstein journal of organic chemistry 20050101

• Synthesis and biological action of 1-aminomethyl derivatives of 3-R-4-phenyl-delta2-1,2,4-triazoline-5-thione.

  Acta poloniae pharmaceutica 20050101

• Comparison of single-agent androgen suppression for advanced prostate cancer.

  Reviews in urology 20050101

• The broadly insecticidal Photorhabdus luminescens toxin complex a (Tca): activity against the Colorado potato beetle, Leptinotarsa decemlineata, and sweet potato whitefly, Bemisia tabaci.

  Journal of insect science (Online) 20050101

• Insertion of an aspartic acid moiety into cyclic pseudopeptides: synthesis and biological characterization of potent antagonists for the human Tachykinin NK-2 receptor.

  Journal of medicinal chemistry 20041230

• Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.

  Journal of medicinal chemistry 20041216

• Characterization of inward-rectifier K+ channel inhibition by antiarrhythmic piperazine.

  Biochemistry 20041214

• Novel bicyclic piperazine derivatives of triazolotriazine and triazolopyrimidines as highly potent and selective adenosine A2A receptor antagonists.

  Journal of medicinal chemistry 20041202

• Structure-activity relationships in platelet-activating factor. 12. Synthesis and biological evaluation of platelet-activating factor antagonists with anti-HIV-1 activity.

  Journal of medicinal chemistry 20041202

• Structure determination of a sildenafil analogue contained in commercial herb drinks.

  Magnetic resonance in chemistry : MRC 20041201

• Kv3 voltage-gated potassium channels regulate neurotransmitter release from mouse motor nerve terminals.

  The European journal of neuroscience 20041201

• A diketopiperazine dimer from a marine-derived isolate of Aspergillus niger.

  Journal of natural products 20041201

• Severe carpal tunnel syndrome in a patient with juvenile idiopathic arthritis due to proximal migration of hypertrophic lumbrical muscles.

  Clinical rheumatology 20041201

• Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5).

  Neurochemistry international 20041101

• Structure of an anti-DNA fab complexed with a non-DNA ligand provides insights into cross-reactivity and molecular mimicry.

  Proteins 20041101

• Treatment of endometrial stromal sarcoma with a gonadotropin-releasing hormone analogue.

  Obstetrics and gynecology 20041101

• Gonadotropin-releasing hormone (GnRH) agonist triptorelin inhibits estradiol-induced serum response element (SRE) activation and c-fos expression in human endometrial, ovarian and breast cancer cells.

  European journal of endocrinology 20041101

• The histamine H4 receptor and potential therapeutic uses for H4 ligands.

  Mini reviews in medicinal chemistry 20041101

• Eudragit E accelerated the diketopiperazine formation of enalapril maleate determined by thermal FTIR microspectroscopic technique.

  Pharmaceutical research 20041101

• [Triptorelin. A hormonal treatment for prostate cancer].

  Revue de l'infirmiere 20041101

• [Clinical study of subcutaneous administration of gonadotropin-releasing hormone agonist every six weeks in girls with idiopathic central precocious puberty].

  Zhonghua er ke za zhi = Chinese journal of pediatrics 20041101

• Synthesis and anticonvulsant activity of some piperazine derivatives.

  Bollettino chimico farmaceutico 20041101

• Stereochemistry of C-6 nucleophilic displacements on 1,1-difluorocyclopropyldibenzosuberanyl substrates. An improved synthesis of multidrug resistance modulator LY335979 trihydrochloride.

  The Journal of organic chemistry 20041029

• Oxidative C-arylation of free (NH)-heterocycles via direct (sp3) C-H bond functionalization.

  Journal of the American Chemical Society 20041020

• Photonucleophilic aromatic substitution of 6-fluoroquinolones in basic media: triplet quenching by hydroxide anion.

  The Journal of organic chemistry 20041015

• Electrophoretic behavior and pKa determination of quinolones with a piperazinyl substituent by capillary zone electrophoresis.

  Journal of chromatography. A 20041008

• Active force inhibition and stretch-induced force enhancement in frog muscle treated with BDM.

  Journal of applied physiology (Bethesda, Md. : 1985) 20041001

• Half-dose depot triptorelin in pituitary suppression for multiple ovarian stimulation in assisted reproduction technology: a randomized study.

  Human reproduction (Oxford, England) 20041001

• Effects of 'Legal X' piperazine analogs on dopamine and serotonin release in rat brain.

  Annals of the New York Academy of Sciences 20041001

• Substituted piperazines as novel dipeptidyl peptidase IV inhibitors.

  Bioorganic & medicinal chemistry letters 20040920

• Synthesis and structure--activity relationship in a class of indolebutylpiperazines as dual 5-HT(1A) receptor agonists and serotonin reuptake inhibitors.

  Journal of medicinal chemistry 20040909

• Resistance to fatigue of individual Xenopus single skeletal muscle fibres is correlated with mitochondrial volume density.

  Experimental physiology 20040901

• 1-Methylpiperazine-1,4-diium 4-nitrophthalate(2-) 4-nitrophthalic acid monohydrate.

  Acta crystallographica. Section C, Crystal structure communications 20040901

• Modeling of the D2 dopamine receptor arylpiperazine binding site for 1-[2-[5-(1H-benzimidazole-2-thione)]ethyl]-4-arylpiperazines.

  Archiv der Pharmazie 20040901

• Compression of the radial branch of the median nerve due to an anomalous muscle belly of the first lumbrical in a child.

  The Mount Sinai journal of medicine, New York 20040901

• Efficacy and safety of a metabolic modulator drug in chronic stable angina: review of evidence from clinical trials.

  Journal of cardiovascular pharmacology and therapeutics 20040901

• Surgical correction of crossover deformity of the second toe: a technique for tenodesis.

  Foot & ankle international 20040901

• New substituted piperazines as ligands for melanocortin receptors. Correlation to the X-ray structure of 'THIQ'.

  Journal of medicinal chemistry 20040826

• Synthesis and biological characterization of novel hybrid 7-[[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino]-5,6,7,8-tetrahydro-naphthalen-2-ol and their heterocyclic bioisosteric analogues for dopamine D2 and D3 receptors.

  Bioorganic & medicinal chemistry 20040815

• Piperazine derivatives of [1,2,4]triazolo[1,5-a][1,3,5]triazine as potent and selective adenosine A2a receptor antagonists.

  Journal of medicinal chemistry 20040812

• Complexation of metals with piperazine-containing azamacrocyclic fluorophores.

  The Journal of organic chemistry 20040806

• Anti-angiogenic and anti-tumor apoptotic activities of SJ-8002, a new piperazine derivative.

  International journal of oncology 20040801

• Studies on the human metabolism and the toxicologic detection of the cough suppressant dropropizine in urine using gas chromatography-mass spectrometry.

  Therapeutic drug monitoring 20040801

• Effect of different pharmacologic and chemical agents on the integrity of hydatid cyst membranes.

  AJR. American journal of roentgenology 20040801

• Synthesis and antibacterial activity of 2-(4-substituted phenyl)-3(2H)-isothiazolones.

  European journal of medicinal chemistry 20040801

• Oxidation of tyrosine diketopiperazine to DOPA diketopiperazine with tyrosine hydroxylase.

  Journal of natural products 20040801

• Effect of temperature on the chromatographic retention of ionizable compounds. I. Methanol-water mobile phases.

  Journal of chromatography. A 20040709

• Does a reinforced kinetic macrocyclic effect exist? the demetallation in strong acid of copper(II) Complexes with open and cyclic tetramines containing a piperazine fragment.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20040705

• Synthesis and functional activity of (2-aryl-1-piperazinyl)-N-(3-methylphenyl)acetamides: selective dopamine D4 receptor agonists.

  Bioorganic & medicinal chemistry 20040701

• GnRH analogs: depot versus short formulations.

  European journal of obstetrics, gynecology, and reproductive biology 20040701

• Force enhancement in single skeletal muscle fibres on the ascending limb of the force-length relationship.

  The Journal of experimental biology 20040701

• (R)-4-(4-fluorophenyl)-1-[2-hydroxy-2-(3-methyl-1-benzofuran-2-yl)ethyl]piperazinium chloride propan-1-ol solvate.

  Acta crystallographica. Section C, Crystal structure communications 20040701

• Antiproliferative effects of the GnRH antagonist cetrorelix and of GnRH-II on human endometrial and ovarian cancer cells are not mediated through the GnRH type I receptor.

  European journal of endocrinology 20040701

• Partially retained small finger flexor digitorum profundus function despite complete tendon loss in the forearm.

  The Journal of hand surgery 20040701

• Luteal phase defects following agonist-triggered ovulation: a patient-dependent response.

  Reproductive biomedicine online 20040701

• Association of inhibin B serum levels with parameters of follicular response in a randomized controlled trial comparing gnRH agonist versus antagonist protocols for ovarian hyperstimulation.

  Journal of assisted reproduction and genetics 20040701

• A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells.

  The Journal of biological chemistry 20040618

• Hemolysate-filled polyethyleneimine and polyurea microcapsules as potential red blood cell substitutes: effect of aqueous monomer type on properties of the prepared microcapsules.

  International journal of pharmaceutics 20040618

• Decarboxylation of 6-nitrobenzisoxazole-3-carboxylate as kinetic probe for piperazinium-based cationic micelles.

  Journal of colloid and interface science 20040615

• Chiral, nonracemic (piperazin-2-yl)methanol derivatives with sigma-receptor affinity.

  Bioorganic & medicinal chemistry 20040615

• Somatic mutations of KIT in familial testicular germ cell tumours.

  British journal of cancer 20040614

• Cutaneous drug eruption from cetirizine and hydroxyzine.

  Journal of the American Academy of Dermatology 20040601

• Antiviral properties of quinolone-based drugs.

  Current drug targets. Infectious disorders 20040601

• An open and randomized study comparing the efficacy of standard danazol and modified triptorelin regimens for postoperative disease management of moderate to severe endometriosis.

  Fertility and sterility 20040601

• Studies on the metabolism and the toxicological analysis of the nootropic drug fipexide in rat urine using gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040525

• Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidines: a novel class of potent enterovirus inhibitors.

  Bioorganic & medicinal chemistry letters 20040517

• Parallel solution-phase synthesis of conformationally restricted congeners of pentamidine and evaluation of their antiplasmodial activities.

  Journal of medicinal chemistry 20040506

• Enhancement of embryo developmental potential by a single administration of GnRH agonist at the time of implantation.

  Human reproduction (Oxford, England) 20040501

• Optically active antifungal azoles: synthesis and antifungal activity of (2R,3S)-2-(2,4-difluorophenyl)-3-(5-[2-[4-aryl-piperazin-1-yl]-ethyl]-tetrazol-2-yl/1-yl)-1-[1,2,4]-triazol-1-yl-butan-2-ol.

  Bioorganic & medicinal chemistry 20040501

• Synthesis and evaluation of anticonvulsant and antimicrobial activities of 3-hydroxy-6-methyl-2-substituted 4h-pyran-4-one derivatives.

  Archiv der Pharmazie 20040501

• The septa of Legueu and Juvara: an anatomic study.

  The Journal of hand surgery 20040501

• Infection with pinworms (Syphacia obvelata) does not affect the plasma corticosterone concentration in male, nonpregnant female, and pregnant female rats.

  Contemporary topics in laboratory animal science 20040501

• Accelerated versus slowly progressive forms of puberty in girls with precocious and early puberty. Gonadotropin suppressive effect and final height obtained with two different analogs.

  Journal of pediatric endocrinology & metabolism : JPEM 20040501

• Structure elucidation of a new diketopiperazine Sch 725418 from Micromonospora sp.

  The Journal of antibiotics 20040501

• [Ion-exchange chromatographic behavior and characterization of Staphylococcus aureus in exponential phase].

  Se pu = Chinese journal of chromatography 20040501

• Synthesis, structure, and magnetic properties of amine-templated open-framework nickel(II) sulfates.

  Inorganic chemistry 20040419

• Hydrotropic solubilization of nimesulide for parenteral administration.

  International journal of pharmaceutics 20040415

• Structures of piperazine, piperidine and morpholine.

  Acta crystallographica. Section B, Structural science 20040401

• Synthesis and evaluation of 1-arylsulfonyl-3-piperazinone derivatives as factor Xa inhibitors III. Effect of ring opening of piperazinone moiety on inhibition.

  Chemical & pharmaceutical bulletin 20040401

• Early and late hormonal responses to the microdose gonadotropin-releasing hormone agonist in normal menstruating women.

  Fertility and sterility 20040401

• 3-[4-(4-fluorophenyl)piperazin-1-ylmethyl]-5-methyl-1,3-benzoxazol-2(3H)-one and 3-[4-(2-fluorophenyl)piperazin-1-ylmethyl]-5-methyl-1,3-benzoxazol-2(3H)-one.

  Acta crystallographica. Section C, Crystal structure communications 20040401

• Enoxacin trihydrate.

  Acta crystallographica. Section C, Crystal structure communications 20040401

• [Effects of ovarian stimulation on serum concentrations of lipids and ketone bodies in patients undergoing IVF/ICSI treatment].

  Zentralblatt fur Gynakologie 20040401

• Chemistry, pharmacology, toxicology, and hepatic metabolism of designer drugs of the amphetamine (ecstasy), piperazine, and pyrrolidinophenone types: a synopsis.

  Therapeutic drug monitoring 20040401

• Design, synthesis, and alpha(1)-adrenoceptor binding properties of new arylpiperazine derivatives bearing a flavone nucleus as the terminal heterocyclic molecular portion.

  Bioorganic & medicinal chemistry 20040315

• Identification of BVT.2938 metabolites by LC/MS and LC/MS/MS after in vitro incubations with liver microsomes and hepatocytes.

  Journal of pharmaceutical and biomedical analysis 20040310

• Synthesis of stavudine amino acid ester prodrugs with broad-spectrum chemotherapeutic properties for the effective treatment of HIV/AIDS.

  Bioorganic & medicinal chemistry letters 20040308

• Ciprofloxacin-protected gold nanoparticles.

  Langmuir : the ACS journal of surfaces and colloids 20040302

• 3,5-Substituted phenyl galactosides as leads in designing effective cholera toxin antagonists; synthesis and crystallographic studies.

  Bioorganic & medicinal chemistry 20040301

• Golmaenone, a new diketopiperazine alkaloid from the marine-derived fungus Aspergillus sp.

  Chemical & pharmaceutical bulletin 20040301

• PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040301

• The emergence of selective 5-HT 2B antagonists structures, activities and potential therapeutic applications.

  Mini reviews in medicinal chemistry 20040301

• New designer drug 1-(3,4-methylenedioxybenzyl) piperazine (MDBP): studies on its metabolism and toxicological detection in rat urine using gas chromatography/mass spectrometry.

  Journal of mass spectrometry : JMS 20040301

• Novel inhibitors of fatty acid oxidation as potential metabolic modulators.

  Bioorganic & medicinal chemistry letters 20040223

• The influence of the boat-to-chair conversion on the demetallation of the nickel(II) complex of an open-chain tetramine containing a piperazine fragment.

  Dalton transactions (Cambridge, England : 2003) 20040221

• Triptorelin versus cetrorelix in intracytoplasmic sperm injection cycles in women with a single ovary.

  European journal of obstetrics, gynecology, and reproductive biology 20040210

• Isoelectric point separation of proteins by capillary pH-gradient ion-exchange chromatography.

  Journal of chromatography. A 20040206

• Adsorption and thermal condensation mechanisms of amino acids on oxide supports. 1. Glycine on silica.

  Langmuir : the ACS journal of surfaces and colloids 20040203

• Identification of a hydroxylamine glucuronide metabolite of an oral hypoglycemic agent.

  Drug metabolism and disposition: the biological fate of chemicals 20040201

• Equivalence of the 3-month and 28-day formulations of triptorelin with regard to achievement and maintenance of medical castration in women with endometriosis.

  Fertility and sterility 20040201

• In vivo metabolism of the new designer drug 1-(4-methoxyphenyl)piperazine (MeOPP) in rat and identification of the human cytochrome P450 enzymes responsible for the major metabolic step.

  Xenobiotica; the fate of foreign compounds in biological systems 20040201

• Synthesis of nitro esters of prednisolone, new compounds combining pharmacological properties of both glucocorticoids and nitric oxide.

  Journal of medicinal chemistry 20040129

• Nonaqueous capillary electrophoresis-mass spectrometry of synthetic polymers.

  Analytical chemistry 20040115

• Synthesis and structures of new pyromellitate coordination polymers with piperazine as a ligand.

  Inorganic chemistry 20040112

• The discovery and synthesis of novel adenosine substituted 2,3-dihydro-1H-isoindol-1-ones: potent inhibitors of poly(ADP-ribose) polymerase-1 (PARP-1).

  Bioorganic & medicinal chemistry letters 20040105

• Pituitary and gonadal effects of GnRH (gonadotropin releasing hormone) analogues in two peripubertal female rat models.

  Pediatric research 20040101

• Towards understanding the tandem mass spectra of protonated oligopeptides. 1: mechanism of amide bond cleavage.

  Journal of the American Society for Mass Spectrometry 20040101

• Dipotassium aquapentafluorovanadate.

  Acta crystallographica. Section C, Crystal structure communications 20040101

• Four trifluoromethylnitrobenzene analogues.

  Acta crystallographica. Section C, Crystal structure communications 20040101

• Combination of LHRH analog with somatostatin analog and dexamethasone versus chemotherapy in hormone-refractory prostate cancer: a randomized phase II study.

  Urology 20040101

• Quantitative structure-activity relationship analysis of the substituent effects on the binding affinity of derivatives of trimetazidine.

  Arzneimittel-Forschung 20040101

• The use of solid-phase supported 1-N-piperazine-4-N-carboxaldehyde in Vilsmeier reactions.

  Journal of combinatorial chemistry 20040101

• XR5967, a novel modulator of plasminogen activator inhibitor-1 activity, suppresses tumor cell invasion and angiogenesis in vitro.

  Anti-cancer drugs 20040101

• Competitive induction and enhancement of indole and a diketopiperazine in marine bacteria.

  Marine biotechnology (New York, N.Y.) 20040101

• The outer membrane protein Omp35 affects the reduction of Fe(III), nitrate, and fumarate by Shewanella oneidensis MR-1.

  BMC microbiology 20040101

• Synthesis and conformation analysis of 3-substituted derivatives of 1H,3H-pyrido[2,3-d] pyrimidin-4-one of expected depressive nervous system. Part III.

  Acta poloniae pharmaceutica 20040101

• Luteinizing hormone-releasing hormone (LHRH) inhibits apoptosis induced by cytotoxic agent and UV-light but not apoptosis mediated through CD95 in human ovarian and endometrial cancer cells.

  Anticancer research 20040101

• The outer membrane cytochromes of Shewanella oneidensis MR-1 are lipoproteins.

  Letters in applied microbiology 20040101

• Pharmacodynamic equivalence of a decapeptyl 3-month SR formulation with the 28-day SR formulation in patients with advanced prostate cancer.

  Hormone research 20040101

• [The alkaloids of Penicillium aurantiogriseum Dierckx (1901) var. aurantiogriseum VKM F-1298].

  Mikrobiologiia 20040101

• Electrospray mass spectrometry of a series of mixed nitrido 99gTc- heterocomplexes conjugated with bioactive molecules.

  European journal of mass spectrometry (Chichester, England) 20040101

• Spectroscopic properties of various quinolone antibiotics in aqueous-organic solvent mixtures.

  Photochemistry and photobiology 20040101

• Synthesis and antiviral properties of arabino and ribonucleosides of 1,3-dideazaadenine, 4-nitro-1,3-dideazapurine and diketopiperazine.

  Nucleosides, nucleotides & nucleic acids 20040101

• Determination of the active site protonation state of beta-secretase from molecular dynamics simulation and docking experiment: implications for structure-based inhibitor design.

  Journal of the American Chemical Society 20031231

• Evaluation of anthelmintic properties of extracts from some plants used as livestock dewormers by pastoralist and smallholder farmers in Kenya against Heligmosomoides polygyrus infections in mice.

  Veterinary parasitology 20031230

• Direct activation by dopamine of recombinant human 5-HT1A receptors: comparison with human 5-HT2C and 5-HT3 receptors.

  Synapse (New York, N.Y.) 20031215

• Equilibrium studies in solution involving nickel(II) complexes of flexidentate Schiff base ligands: isolation and structural characterization of the planar red and octahedral green species involved in the equilibrium.

  Inorganic chemistry 20031215

• The (2-phenyl-2-trimethylsilyl)ethyl-(PTMSEL)-linker in the synthesis of glycopeptide partial structures of complex cell surface glycoproteins.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20031215

• Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A.

  International journal of cancer 20031210

• Syntheses and binding studies of new [(aryl)(aryloxy)methyl]piperidine derivatives and related compounds as potential antidepressant drugs with high affinity for serotonin (5-HT) and norepinephrine (NE) transporters.

  Journal of medicinal chemistry 20031204

• Array synthesis of novel lipodepsipeptide.

  Bioorganic & medicinal chemistry letters 20031201

• LH serum levels during ovarian stimulation as predictors of ovarian response and assisted reproduction outcome in down-regulated women stimulated with recombinant FSH.

  Human reproduction (Oxford, England) 20031201

• Experimental and theoretical investigation of the main fragmentation pathways of protonated H-Gly-Gly-Sar-OH and H-Gly-Sar-Sar-OH.

  Journal of the American Society for Mass Spectrometry 20031201

• Piperazine quaternary diammonium salts as additives to background electrolytes in capillary zone electrophoresis.

  Electrophoresis 20031201

• Activation of trans geometry in bifunctional mononuclear platinum complexes by a piperidine ligand. Mechanistic studies on antitumor action.

  The Journal of biological chemistry 20031128

• Rational design and synthesis of androgen receptor-targeted nonsteroidal anti-androgen ligands for the tumor-specific delivery of a doxorubicin-formaldehyde conjugate.

  Journal of medicinal chemistry 20031120

• A novel route for the synthesis of piperazine from N-(2,3-dihydroxypropyl)ethylenediamine over composite photocatalysts.

  Chemical communications (Cambridge, England) 20031107

• Massive gastrointestinal bleeding in infants with ascariasis.

  Journal of pediatric surgery 20031101

• Effects of a piperidine ligand on DNA modification by antitumor cisplatin analogues.

  Chemical research in toxicology 20031101

• Synthesis and structure-activity relationship of di-(3, 8-diazabicyclo[3.2.1]octane) diquaternary ammonium salts as unique analgesics.

  Archiv der Pharmazie 20031101

• Solid-phase polyamine synthesis using piperazine and piperidine building blocks.

  Organic letters 20031030

• Solution and solid state 13C NMR and X-ray studies of genistein complexes with amines. Potential biological function of the C-7, C-5, and C4'-OH groups.

  Organic & biomolecular chemistry 20031021

• Preparation and characterization of prototypes for multi-modal separation media aimed for capture of negatively charged biomolecules at high salt conditions.

  Journal of chromatography. A 20031017

• The effect of GnRH analogs on urinary incontinence after ablation of the ovaries in dogs.

  Theriogenology 20031015

• Synthesis and biological activity of piperazine-based dual MMP-13 and TNF-alpha converting enzyme inhibitors.

  Bioorganic & medicinal chemistry letters 20031006

• Formation of p-cresol:piperazine complex in solution monitored by spin-lattice relaxation times and pulsed field gradient NMR diffusion measurements.

  Journal of magnetic resonance (San Diego, Calif. : 1997) 20031001

• dd-diketopiperazines: antibiotics active against Vibrio anguillarum isolated from marine bacteria associated with cultures of Pecten maximus.

  Journal of natural products 20031001

• An action plan to prevent and combat threadworm infection.

  Nursing times 20031001

• [NMR studies on cetirizine hydrochloride].

  Yao xue xue bao = Acta pharmaceutica Sinica 20031001

• Assembly of hybrid organic-organometallic materials through mechanochemical acid-base reactions.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20030922

• Debenzylation of tertiary amines using phosgene or triphosgene: an efficient and rapid procedure for the preparation of carbamoyl chlorides and unsymmetrical ureas. Application in carbon-11 chemistry.

  The Journal of organic chemistry 20030919

• Effects of a Gonadotropin-Releasing Hormone agonist and Follicle Stimulating Hormone on the incidence of apoptosis in human luteinized granulosa cells.

  European journal of obstetrics, gynecology, and reproductive biology 20030910

• Do secondary and tertiary ammonium cations act as structure-directing agents in the formation of layered uranyl selenites?

  Inorganic chemistry 20030908

• Novel diphenylalkyl piperazine derivatives with high affinities for the dopamine transporter.

  Bioorganic & medicinal chemistry 20030901

• Osteoporosis and prostate cancer.

  British journal of cancer 20030901

• Nonsupplemented luteal phase characteristics after the administration of recombinant human chorionic gonadotropin, recombinant luteinizing hormone, or gonadotropin-releasing hormone (GnRH) agonist to induce final oocyte maturation in in vitro fertilization patients after ovarian stimulation with recombinant follicle-stimulating hormone and GnRH antagonist cotreatment.

  The Journal of clinical endocrinology and metabolism 20030901

• Cyclooctadepsipeptides--an anthelmintically active class of compounds exhibiting a novel mode of action.

  International journal of antimicrobial agents 20030901

• New designer drug 1-(3-trifluoromethylphenyl) piperazine (TFMPP): gas chromatography/mass spectrometry and liquid chromatography/mass spectrometry studies on its phase I and II metabolism and on its toxicological detection in rat urine.

  Journal of mass spectrometry : JMS 20030901

• Influence of pH on electrophoretic behavior of phenothiazines and determination of pKa values by capillary zone electrophoresis.

  Electrophoresis 20030901

• Synthesis and in vitro antibacterial evaluation of N-[5-(5-nitro-2-thienyl)-1,3,4-thiadiazole-2-yl] piperazinyl quinolones.

  European journal of medicinal chemistry 20030901

• Perioperative factors for predicting successful hysteroscopic endometrial ablation.

  The Journal of reproductive medicine 20030901

• Treatment of polycythemia vera and essential thrombocythemia: the role of pipobroman.

  Leukemia & lymphoma 20030901

• [Antithrombotic effects of morpholine and piperazine ring derivatives and their molecular mechanism].

  Yao xue xue bao = Acta pharmaceutica Sinica 20030901

• Quantitative determination of some pharmaceutical piperazine derivatives through complexation with iron(III) chloride.

  Farmaco (Societa chimica italiana : 1989) 20030801

• Comparative efficacy of triptorelin pamoate and leuprolide acetate in men with advanced prostate cancer.

  BJU international 20030801

• 2-(2-Naphthyloxy)acetate derivatives. II. A new class of antiamnesic agents.

  Acta crystallographica. Section C, Crystal structure communications 20030801

• [Effect of low-dose triptorelin on pituitary down-regulation for patients undergoing in vitro fertilization and embryo transfer].

  Zhonghua nan ke xue = National journal of andrology 20030801

• GnRH agonist treatment before total laparoscopic hysterectomy for large uteri.

  The Journal of the American Association of Gynecologic Laparoscopists 20030801

• 1,4-benzothiazine analogues and apoptosis: structure-activity relationship.

  Bioorganic & medicinal chemistry 20030731

• 4-Aminopiperidine derivatives as a new class of potent cognition enhancing drugs.

  Bioorganic & medicinal chemistry letters 20030721

• Asymmetric synthesis of substituted 1-aminocyclopropane-1-carboxylic acids via diketopiperazine methodology.

  Organic & biomolecular chemistry 20030721

• Crystal engineering of novel cocrystals of a triazole drug with 1,4-dicarboxylic acids.

  Journal of the American Chemical Society 20030716

• The human chorionic gonadotropin test is more powerful than the gonadotropin-releasing hormone agonist test to discriminate male isolated hypogonadotropic hypogonadism from constitutional delayed puberty.

  European journal of endocrinology 20030701

• Actions of GnRH antagonists on IGF-II, IGF-binding protein-2 and pregnancy-associated plasma protein-A in human granulosa-lutein cells.

  European journal of endocrinology 20030701

• Quantitative enantiomeric analysis of chlorcyclizine, hydroxyzine, and meclizine by capillary electrophoresis.

  Analytical and bioanalytical chemistry 20030701

• Doppler-ultrasound as a predictor of uterine fibroid response to GnRH therapy.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20030701

• Pregnancy in a 46-year-old woman after autologous granular cell mitochondria transfer.

  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030701

• Carpal tunnel syndrome due to gouty infiltration of the lumbrical muscles and flexor tendons.

  Hand surgery : an international journal devoted to hand and upper limb surgery and related research : journal of the Asia-Pacific Federation of Societies for Surgery of the Hand 20030701

• Synthesis and characterization of the first fluorescent antagonists for human 5-HT4 receptors.

  Journal of medicinal chemistry 20030619

• Two novel and selective nonimidazole histamine H3 receptor antagonists A-304121 and A-317920: I. In vitro pharmacological effects.

  The Journal of pharmacology and experimental therapeutics 20030601

• Gonadotropin-releasing hormone agonist treatment before abdominal myomectomy: a controlled trial.

  Fertility and sterility 20030601

• Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry.

  Journal of mass spectrometry : JMS 20030601

• Ascorbic acid and infertility treatment.

  Central European journal of public health 20030601

• [Camptodactylies].

  Chirurgie de la main 20030601

• [An experimental study on the apoptosis of rabbit small intestinal cells during early postburn stage].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20030601

• Using spin dynamics of covalently linked radical ion pairs to probe the impact of structural and energetic changes on charge recombination.

  Journal of the American Chemical Society 20030528

• DNA binding mode of the cis and trans geometries of new antitumor nonclassical platinum complexes containing piperidine, piperazine, or 4-picoline ligand in cell-free media. Relations to their activity in cancer cell lines.

  Biochemistry 20030527

• Design, synthesis and biological evaluation of oxazolidinone-quinolone hybrids.

  Bioorganic & medicinal chemistry 20030515

• Design of selective peptidomimetic agonists for the human orphan receptor BRS-3.

  Journal of medicinal chemistry 20030508

• Structural properties of dibenzosuberanylpiperazine derivatives for efficient reversal of chloroquine resistance in Plasmodium chabaudi.

  Journal of medicinal chemistry 20030508

• Dihydropiperazine neonicotinoid compounds. Synthesis and insecticidal activity.

  Journal of agricultural and food chemistry 20030507

• Effect of extracellular PO2 on the fall in intracellular PO2 in contracting single myocytes.

  Journal of applied physiology (Bethesda, Md. : 1985) 20030501

• Adverse drug reactions: implications for the development of fluoroquinolones.

  The Journal of antimicrobial chemotherapy 20030501

• Isoprenaline-stimulated differential adrenergic response of K+ channels in skeletal muscle under hypokalaemic conditions.

  Pflugers Archiv : European journal of physiology 20030501

• The synthesis of functionalized nanoscale molecular rods of defined length.

  Journal of the American Chemical Society 20030423

• Syntheses of novel diphenyl piperazine derivatives and their activities as inhibitors of dopamine uptake in the central nervous system.

  Bioorganic & medicinal chemistry 20030417

• Study on synthesis, characterization and biological activity of some new nitrogen heterocycle porphyrins.

  Bioorganic & medicinal chemistry 20030417

• Synthesis and biological activity of N-arylpiperazine-modified analogues of KN-62, a potent antagonist of the purinergic P2X7 receptor.

  Journal of medicinal chemistry 20030410

• Mapping the influence of molecular structure on rates of electron transfer using direct measurements of the electron spin-spin exchange interaction.

  Journal of the American Chemical Society 20030402

• Lumbrical tears in rock climbers.

  Journal of hand surgery (Edinburgh, Scotland) 20030401

• Phosphonopropionic acid as a building block in supramolecular chemistry: salts with organic diamines.

  Acta crystallographica. Section B, Structural science 20030401

• Crystal structure of [1,4-bis[1-(3,5-dichlorophenolato-2-ylmethyl)-ylpropylamino-kappa2N,O]piperazine-kappa2N,N']cobalt(II).

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030401

• The first organically templated 1D lithioberyllofluoride chain, [LiBe2F7][C4N2H12] [H2O]1.5.

  Chemical communications (Cambridge, England) 20030321

• Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety.

  Behavioural brain research 20030318

• Trypanocidal activity of conformationally restricted pentamidine congeners.

  Journal of medicinal chemistry 20030313

• Novel diketopiperazine enhances motor and cognitive recovery after traumatic brain injury in rats and shows neuroprotection in vitro and in vivo.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030301

• Neuroprotective and nootropic actions of a novel cyclized dipeptide after controlled cortical impact injury in mice.

  Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20030301

• Antibodies to the quinolones and fluoroquinolones for the development of generic and specific immunoassays for detection of these residues in animal products.

  Food additives and contaminants 20030301

• Bone mass at final height in precocious puberty after gonadotropin-releasing hormone agonist with and without calcium supplementation.

  The Journal of clinical endocrinology and metabolism 20030301

• Piperazine N-substituted naphthyridines, pyridothienopyrimidines and pyridothienotriazines: new antiprotozoals active against Philasterides dicentrarchi.

  European journal of medicinal chemistry 20030301

• Surgical reconstruction of irreversible ulnar nerve paralysis in leprosy.

  Leprosy review 20030301

• Molecular structures of human factor Xa complexed with ketopiperazine inhibitors: preference for a neutral group in the S1 pocket.

  Journal of medicinal chemistry 20030227

• Muscle spindles in the deep muscles of the human neck: a morphological and immunocytochemical study.

  The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20030201

• (1R,3S)-Camphoric acid as a building block in supramolecular chemistry: adducts with organic polyamines.

  Acta crystallographica. Section B, Structural science 20030201

• Synthesis of eosinophil infiltration inhibitors with antihistaminic activity.

  Chemical & pharmaceutical bulletin 20030201

• Crystal structure of the 1:2:2 adduct of piperazine, o-phthalic acid and water.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201

• Novel antifungal diketopiperazine from marine fungus.

  The Journal of antibiotics 20030201

• New arylpiperazine derivatives with high affinity for alpha1A, D2 and 5-HT2A receptors.

  Bioorganic & medicinal chemistry letters 20030120

• Identification of phenylisoxazolines as novel and viable antibacterial agents active against Gram-positive pathogens.

  Journal of medicinal chemistry 20030116

• N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors.

  Bioorganic & medicinal chemistry letters 20030106

• Ligand effects on the binding of cis- and trans-[PtCl(2)Am(1)Am(2)] to proteins.

  Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20030101

• Intrafusal fiber type composition of muscle spindles in the first human lumbrical muscle.

  Acta neuropathologica 20030101

• Intramuscular lipoma in an anomalous muscle belly of the middle finger lumbrical as a cause of carpal tunnel syndrome and trigger wrist.

  Orthopedics 20030101

• Human growth hormone and gonadotropin releasing hormone analog combination therapy increases predicted height in short normal girls.

  Clinical pediatrics 20030101

• Antiprolactinemic approach in the treatment of metastatic breast cancer: a phase II study of polyneuroendocrine therapy with LHRH-analogue, tamoxifen and the long-acting antiprolactinemic drug cabergoline.

  Anticancer research 20030101

• Structure-activity relationship studies: M2 and CCR5 receptor antagonists.

  Current topics in medicinal chemistry 20030101

• Overlapping role of the outer membrane cytochromes of Shewanella oneidensis MR-1 in the reduction of manganese(IV) oxide.

  Letters in applied microbiology 20030101

• Solid-phase parallel synthesis of 17alpha-substituted estradiol sulfamate and phenol libraries using the multidetachable sulfamate linker.

  Journal of combinatorial chemistry 20030101

• Cell surface exposure of the outer membrane cytochromes of Shewanella oneidensis MR-1.

  Letters in applied microbiology 20030101

• Ovarian responses to recombinant FSH or HMG in normogonadotrophic women following pituitary desensitization by a depot GnRH agonist for assisted reproduction.

  Reproductive biomedicine online 20030101

• The limited utility of electrocardiography variables used to predict arrhythmia in psychotropic drug overdose.

  Critical care (London, England) 20030101

• [Isolation of Penicillium DIERCKX 1901--a producer of diketopiperazine alkaloids rokefortin and 3,12-dihydrokefortin--from permafrost].

  Prikladnaia biokhimiia i mikrobiologiia 20030101

• Estrogen, progesterone and epithelial ovarian cancer.

  Reproductive biology and endocrinology : RB&E 20030101

• Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer.

  Reproductive biology and endocrinology : RB&E 20030101

• Antituberculosis agents. IX. In vitro antimycobacterial activity of N-(2-phenyl-2-oxoethyl) and N-[2-(4-fluorophenyl)-2-oxoethyl]ciprofloxacin derivatives against some drug-resistant strains of Mycobacterium tuberculosis and Mycobacterium avium isolates.

  Bollettino chimico farmaceutico 20030101

• Piperazine-derived designer drug 1-(3-chlorophenyl)piperazine (mCPP): GC-MS studies on its metabolism and its toxicological detection in rat urine including analytical differentiation from its precursor drugs trazodone and nefazodone.

  Journal of analytical toxicology 20030101

• Gonadotropin releasing hormone analogue (GnRHa) alters the expression and activation of Smad in human endometrial epithelial and stromal cells.

  Reproductive biology and endocrinology : RB&E 20030101

• GnRH agonist administration after embryo transfer, in long protocol stimulated cycles, prevents ovarian hyperstimulation syndrome. A report of five cases.

  In vivo (Athens, Greece) 20030101

• [The history of the development and changes of quinolone antibacterial agents].

  Yakushigaku zasshi 20030101

• Synthesis, spectral and antibacterial studies of binuclear titanium(IV) / zirconium(IV) complexes of piperazine dithiosemicarbazones.

  Bioinorganic chemistry and applications 20030101

• Enantiomeric separation of substituted 2-arylindoles on derivatised polysaccharide chiral stationary phases.

  Journal of biochemical and biophysical methods 20021231

• Progress in arylpiperazine synthesis by the catalytic amination reaction.

  Bioorganic & medicinal chemistry 20021201

• The formation of paracetamol (acetaminophen) adducts with hydrogen-bond acceptors.

  Acta crystallographica. Section B, Structural science 20021201

• Comparison of leuprolide acetate and triptorelin in assisted reproductive technology cycles: a prospective, randomized study.

  Fertility and sterility 20021201

• The albonoursin gene Cluster of S noursei biosynthesis of diketopiperazine metabolites independent of nonribosomal peptide synthetases.

  Chemistry & biology 20021201

• Median and ulnar nerve compression at the wrist caused by anomalous muscles.

  Acta orthopaedica Belgica 20021201

• New N-pyridinyl(methyl)-indole-2- and 3-(alkyl)carboxamides and derivatives acting as systemic and topical inflammation inhibitors.

  Journal of enzyme inhibition and medicinal chemistry 20021201

• Novel soluble cationic trans-diaminedichloroplatinum(II) complexes that are active against cisplatin resistant ovarian cancer cell lines.

  Journal of medicinal chemistry 20021121

• Novel apoptosis-inducing trans-platinum piperidine derivatives: synthesis and biological characterization.

  Journal of medicinal chemistry 20021121

• Design, synthesis, and tripeptidyl peptidase II inhibitory activity of a novel series of (S)-2,3-dihydro-2-(4-alkyl-1H-imidazol-2-yl)-1H-indoles.

  Journal of medicinal chemistry 20021121

• A modified synthesis of iodoazidoaryl prazosin.

  The Journal of organic chemistry 20021115

• Predicting drug-induced agranulocytosis: characterizing neutrophil-generated metabolites of a model compound, DMP 406, and assessing the relevance of an in vitro apoptosis assay for identifying drugs that may cause agranulocytosis.

  Chemico-biological interactions 20021110

• New pyridobenzodiazepine derivatives: modifications of the basic side chain differentially modulate binding to dopamine (D(4.2), D(2L)) and serotonin (5-HT(2A)) receptors.

  Journal of medicinal chemistry 20021107

• Indoline and piperazine containing derivatives as a novel class of mixed D(2)/D(4) receptor antagonists. Part 1: identification and structure-activity relationships.

  Bioorganic & medicinal chemistry letters 20021104

• Indoline and piperazine containing derivatives as a novel class of mixed D(2)/D(4) receptor antagonists. Part 2: asymmetric synthesis and biological evaluation.

  Bioorganic & medicinal chemistry letters 20021104

• Synthesis and NK(1)/NK(2) binding activities of a series of diacyl-substituted 2-arylpiperazines.

  Bioorganic & medicinal chemistry letters 20021104

• Substituted uracil derivatives as potent inhibitors of poly(ADP-ribose)polymerase-1 (PARP-1).

  Bioorganic & medicinal chemistry letters 20021104

• Estrogens, but not androgens, regulate expression and functional activity of oxytocin receptor in rabbit epididymis.

  Endocrinology 20021101

• [Cutaneous drug eruption with two antihistaminic drugs of a same chemical family: cetirizine and hydroxyzine].

  Annales de dermatologie et de venereologie 20021101

• Intracytoplasmic injection of frozen-thawed epididymal spermatozoa in a nonhuman primate model, the cynomolgus monkey (Macaca fascicularis).

  Theriogenology 20021015

• Design and synthesis of a pro-drug of vinblastine targeted at treatment of prostate cancer with enhanced efficacy and reduced systemic toxicity.

  Journal of medicinal chemistry 20021010

• The first organically templated thorium compounds, [C4N2H12]0.5[ThF5] and [C5N2H14][ThF6].0.5H2O.

  Chemical communications (Cambridge, England) 20021007

• Unusual cerebellar ataxia: 'worm wobble' revisited.

  Archives of disease in childhood 20021001

• Fleroxacin hydrochloride hydrate.

  Acta crystallographica. Section C, Crystal structure communications 20021001

• Anatomy of the intrinsic hand muscles revisited: part II. Lumbricals.

  Plastic and reconstructive surgery 20021001

• Natural abundance nitrogen-15 nuclear magnetic resonance spectral studies on selected donors.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001

• Ovarian hyperstimulation-like syndrome after administration of triptorelin to a woman with endometriosis.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20021001

• Potent and selective inhibitors of PDGF receptor phosphorylation. 2. Synthesis, structure activity relationship, improvement of aqueous solubility, and biological effects of 4-[4-(N-substituted (thio)carbamoyl)-1-piperazinyl]-6,7-dimethoxyquinazoline derivatives.

  Journal of medicinal chemistry 20020926

• Diastereoisomeric singly bridged cyclophosphazene-macrocyclic compounds.

  Inorganic chemistry 20020923

• Novel inhibitors of plasminogen activator inhibitor-1: development of new templates from diketopiperazines.

  Bioorganic & medicinal chemistry letters 20020902

• Intramolecular cyclization of diketopiperazine formation in solid-state enalapril maleate studied by thermal FT-IR microscopic system.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020901

• Antimycobacterial anthraquinone-chromanone compound and diketopiperazine alkaloid from the fungus Chaetomium globosum KMITL-N0802.

  Planta medica 20020901

• Photoinduced N-demethylation of rufloxacin and its methyl ester under aerobic conditions.

  Photochemistry and photobiology 20020901

• 6-Chloropyridazin-3-yl derivatives active as nicotinic agents: synthesis, binding, and modeling studies.

  Journal of medicinal chemistry 20020829

• Pyrrolylquinoxalinediones carrying a piperazine residue represent highly potent and selective ligands to the homomeric kainate receptor GluR5.

  Bioorganic & medicinal chemistry letters 20020819

• Gonadotropin release in periovulatory heifers after GnRH analogs measured by two types of immunoassays.

  Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20020801

• Synthesis and structure-activity relationships of neuromuscular blocking agents.

  Current medicinal chemistry 20020801

• Structure-activity relationships of 6-nitroquinazolines: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation.

  Chemical & pharmaceutical bulletin 20020801

• Synthesis of 2-methylpiperazine by photocatalytic reaction in a non-aqueous suspension of semiconductor-zeolite composite catalysts.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020801

• Effects of chloride transport on bistable behaviour of the membrane potential in mouse skeletal muscle.

  The Journal of physiology 20020701

• Staged flexor tendon reconstruction fingertip to palm.

  The Journal of hand surgery 20020701

• Anaerobic degradation of pyrrolidine and piperidine coupled with nitrate reduction.

  Chemosphere 20020701

• Long-acting GnRH analogue triptorelin therapy in central isosexual precocious puberty.

  Indian pediatrics 20020701

• Empty follicle syndrome associated with ovarian torsion in an in vitro fertilization program.

  JSLS : Journal of the Society of Laparoendoscopic Surgeons 20020701

• Anomalous lumbrical muscles arising from the deep surface of flexor digitorum superficialis muscles in man.

  Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft 20020701

• Studies on the metabolism and toxicological detection of the new designer drug N-benzylpiperazine in urine using gas chromatography-mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020615

• Inhibition of cathepsin G by 2-amino-3,1-benzoxazin-4-ones: kinetic investigations and docking studies.

  Archives of biochemistry and biophysics 20020615

• Kinetic and mechanistic investigation of the aminolysis of 3-methoxyphenyl 3-nitrophenyl thionocarbonate, 3-chlorophenyl 3-nitrophenyl thionocarbonate, and bis(3-nitrophenyl) thionocarbonate.

  The Journal of organic chemistry 20020614

• Differential effect of gonadotropin-releasing hormone analogue treatment on estrogen levels and sulfatase activity in uterine leiomyoma and myometrium.

  Fertility and sterility 20020601

• BX-471 Berlex.

  Current opinion in investigational drugs (London, England : 2000) 20020601

• Synthesis and structure-activity relationships of new arylpiperazines: para substitution with electron-withdrawing groups decrease binding to 5-HT(1A) and D(2A) receptors.

  European journal of medicinal chemistry 20020601

• [Plural absence of the lumbrical muscles observed in bilateral feet of a body].

  Kaibogaku zasshi. Journal of anatomy 20020601

• Luteinizing hormone-releasing hormone induces JunD-DNA binding and extends cell cycle in human ovarian cancer cells.

  Biochemical and biophysical research communications 20020531

• Synthesis, structural evaluation, and estrogen receptor interaction of 2,3-diarylpiperazines.

  Journal of medicinal chemistry 20020523

• A novel approach to determining physicochemical and absorption properties of 6-fluoroquinolone derivatives: experimental assessment.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20020501

• Enhanced pepsin digestion: a novel process for purifying antibody F(ab')(2) fragments in high yield from serum.

  Journal of immunological methods 20020501

• Synthesis of 1-(3-phthalimido-2-oxobutyl)-4-substituted- phenylpiperazines and their anti-HIV reverse transcriptase activity.

  Yao xue xue bao = Acta pharmaceutica Sinica 20020501

• Selective binding of two-armed diketopiperazine receptors to side-chain-protected peptides.

  The Journal of organic chemistry 20020419

• The lumbrical fat graft: a replacement for lost upper eyelid fat.

  Plastic and reconstructive surgery 20020415

• Diastereoselective reactions in glycine templates containing an ent-ardeemin fragment.

  The Journal of organic chemistry 20020405

• Chiral versus racemic building blocks in supramolecular chemistry: tartrate salts of organic diamines.

  Acta crystallographica. Section B, Structural science 20020401

• GnRH antagonist in assisted reproduction: a Cochrane review.

  Human reproduction (Oxford, England) 20020401

• Number of years since menopause: spontaneous bone loss is dependent but response to hormone replacement therapy is independent.

  Bone 20020401

• Dienogest is as effective as triptorelin in the treatment of endometriosis after laparoscopic surgery: results of a prospective, multicenter, randomized study.

  Fertility and sterility 20020401

• Interaction of 1,2,4-substituted piperazines, new serotonin receptor ligands, with 5-HT1A and 5-HT2A receptors.

  Farmaco (Societa chimica italiana : 1989) 20020401

• Horse lumbrical muscle: possible structural and functional reorganization in regressive muscle.

  Anatomia, histologia, embryologia 20020401

• Dipeptides and diketopiperazines in the Yamato-791198 and Murchison carbonaceous chondrites.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20020401

• Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine.

  Journal of medicinal chemistry 20020314

• The synthesis and selective IL-2 inhibitory activity of bis piperazine-phenol Mannich adducts.

  Bioorganic & medicinal chemistry letters 20020311

• Synthesis and structure-activity relationships of M(2)-selective muscarinic receptor ligands in the 1-[4-(4-arylsulfonyl)-phenylmethyl]-4-(4-piperidinyl)-piperazine family.

  Bioorganic & medicinal chemistry letters 20020311

• Piperazine-1,4-diium--2,4-dinitrophenolate--water (1/2/2).

  Acta crystallographica. Section C, Crystal structure communications 20020301

• Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation.

  The Journal of clinical endocrinology and metabolism 20020301

• Structural identification and biological activity of 7-methyl-10,11-ethylenedioxy-20(S)-camptothecin, a photodegradant of lurtotecan.

  Clinical cancer research : an official journal of the American Association for Cancer Research 20020301

• The study on organic nitrates, part V. New derivatives of piperazine potential NO donors.

  The Journal of pharmacy and pharmacology 20020301

• A study of the binding between polymers and peptides, using affinity capillary electrophoresis, applied to polymeric drug delivery systems.

  Electrophoresis 20020301

• [Buspirone increases D2-like dopaminergic receptor density in rat corpus striatum].

  Arquivos de neuro-psiquiatria 20020301

• A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors.

  Bioorganic & medicinal chemistry letters 20020225

• Acylation of 2,5-dimethoxycarbonyl[60]fulleropyrrolidine and synthesis of its multifullerene derivatives.

  The Journal of organic chemistry 20020208

• A post-Amadori inhibitor pyridoxamine also inhibits chemical modification of proteins by scavenging carbonyl intermediates of carbohydrate and lipid degradation.

  The Journal of biological chemistry 20020201

• Endocrine profiles after triggering of final oocyte maturation with GnRH agonist after cotreatment with the GnRH antagonist ganirelix during ovarian hyperstimulation for in vitro fertilization.

  The Journal of clinical endocrinology and metabolism 20020201

• New mu-opioid receptor agonists with phenoxyacetic acid moiety.

  Chemical & pharmaceutical bulletin 20020201

• Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues.

  American journal of obstetrics and gynecology 20020201

• Reaction behaviors of glycine under super- and subcritical water conditions.

  Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20020201

• The gonadotrophin-releasing hormone antagonist ganirelix--history and introductory data.

  Human fertility (Cambridge, England) 20020201

• Orally-effective, long-acting sorbitol dehydrogenase inhibitors: synthesis, structure-activity relationships, and in vivo evaluations of novel heterocycle-substituted piperazino-pyrimidines.

  Journal of medicinal chemistry 20020117

• Improvement in the selectivity and metabolic stability of the serotonin 5-HT(1A) ligand, S 15535: a series of cis- and trans-2-(arylcycloalkylamine) 1-indanols.

  Journal of medicinal chemistry 20020103

• Lumbrical and interossei recording in severe carpal tunnel syndrome.

  Muscle & nerve 20020101

• Mutational analysis of the C-domain in nonribosomal peptide synthesis.

  European journal of biochemistry 20020101

• Combined quantum chemical and RRKM modeling of the main fragmentation pathways of protonated GGG. II. Formation of b(2), y(1), and y(2) ions.

  Rapid communications in mass spectrometry : RCM 20020101

• Sex hormone replacement therapy reverses altered venous contractility in rats after pharmacological ovariectomy.

  Menopause (New York, N.Y.) 20020101

• [The synthesis of cationic glycerolipid acetals containing aliphatic and heterocyclic bases].

  Bioorganicheskaia khimiia 20020101

• [Optimization of the medium and cultivation conditions of Penicillium roquefortii f39 producing the diketopiperazine alkaloid roquefortine].

  Prikladnaia biokhimiia i mikrobiologiia 20020101

• Functional group interactions of a 5-HT3R antagonist.

  BMC biochemistry 20020101

• Pre-operative endometrial thinning agents before endometrial destruction for heavy menstrual bleeding.

  The Cochrane database of systematic reviews 20020101

• Ensaculin (KA-672 HCl): a multitransmitter approach to dementia treatment.

  CNS drug reviews 20020101

• Induction of differentiation in acute promyelocytic leukemia cells (HL-60) by the verticillin derivative Sch 52900.

  Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

• Use of anthelmintics in herbivores and evaluation of risks for the non target fauna of pastures.

  Veterinary research 20020101

• [The value of motor latency difference measurements between the second lumbrical muscle and second interosseous muscle in the diagnosis of carpal tunnel syndrome].

  Neurologia i neurochirurgia polska 20020101

• Solid-supported synthesis of putative peptide beta-turn mimetics via Ugi reaction for diketopiperazine formation.

  Journal of combinatorial chemistry 20020101

• Antituberculosis agents. VI. Activity of a new ciprofloxacin derivative against Mycobacterium avium and some drug-resistant strains of Mycobacterium tuberculosis.

  Bollettino chimico farmaceutico 20020101

• Identification of inhibitory component in cinnamon--O-methoxycinnamaldehyde inhibits CYP1A2 and CYP2E1-.

  Drug metabolism and pharmacokinetics 20020101

• Strategy for structure elucidation of drug metabolites derived from protonated molecules and (MS)n fragmentation of zotepine, tiaramide and their metabolites.

  Drug metabolism and pharmacokinetics 20020101

• Effects of androgen manipulation on postprandial triglyceridaemia, low-density lipoprotein particle size and lipoprotein(a) in men.

  Atherosclerosis 20011201

• A combination therapy of dexamethasone and somatostatin analog reintroduces objective clinical responses to LHRH analog in androgen ablation-refractory prostate cancer patients.

  The Journal of clinical endocrinology and metabolism 20011201

• Biliary ascariasis.

  Indian journal of pediatrics 20011201

• Levels of estrogen and progesterone receptors in the myometrium and leiomyoma tissue after suppression of estrogens with gonadotropin releasing hormone analogs.

  Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20011201

• The discovery of anthranilic acid-based MMP inhibitors. Part 3: incorporation of basic amines.

  Bioorganic & medicinal chemistry letters 20011119

• Three-dimensional quantitative structure-activity relationship (3D-QSAR) models for a novel class of piperazine-based stromelysin-1 (MMP-3) inhibitors: applying a 'divide and conquer' strategy.

  Journal of medicinal chemistry 20011108

• Comparative study of new benzenesulphonamide fluoroquinolones structurally related to ciprofloxacin against selected ciprofloxacin-susceptible and -resistant Gram-positive cocci.

  The Journal of antimicrobial chemotherapy 20011101

• Intermetatarsal spaces: analysis with MR bursography, anatomic correlation, and histopathology in cadavers.

  Radiology 20011101

• Protein kinase C-independent stimulation of activator protein-1 and c-Jun N-terminal kinase activity in human endometrial cancer cells by the LHRH agonist triptorelin.

  European journal of endocrinology 20011101

• Intracellular signaling pathway of FGF-2-modulated corneal endothelial cell migration during wound healing in vitro.

  Experimental eye research 20011101

• Physical and chemical enhancement of transdermal delivery of triptorelin.

  Pharmaceutical research 20011101

• Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man.

  Xenobiotica; the fate of foreign compounds in biological systems 20011101

• N1-phenyl substituted 4-quinolones of tuberculostatic activity.

  Die Pharmazie 20011101

• A new antibiotic CJ-17,665 from Aspergillus ochraceus.

  The Journal of antibiotics 20011101

• Molecular dynamics of 5-HT1A and 5-HT2A serotonin receptors with methylated buspirone analogues.

  Journal of computer-aided molecular design 20011101

• Improvement of some pharmaceutical properties of DY-9760e by sulfobutyl ether beta-cyclodextrin.

  International journal of pharmaceutics 20011023

• Synthesis and in vitro evaluation of a series of diketopiperazine inhibitors of plasminogen activator inhibitor-1.

  Bioorganic & medicinal chemistry letters 20011008

• Polar nitrogen compounds and their behaviour in the drinking water treatment process.

  Water research 20011001

• Lumpidin, a novel biomarker of some ochratoxin a producing penicillia.

  Journal of agricultural and food chemistry 20011001

• New mu-opioid receptor agonists with piperazine moiety.

  Chemical & pharmaceutical bulletin 20011001

• Structure-activity relationships in platelet-activating factor (PAF). 11-From PAF-antagonism to phospholipase A(2) inhibition: syntheses and structure-activity relationships in 1-arylsulfamido-2-alkylpiperazines.

  European journal of medicinal chemistry 20011001

• Quantitative structure-activity relationship study of novel alpha1a-selective adrenoceptor antagonists.

  Journal of enzyme inhibition 20011001

• Kinetics and mechanisms of the reactions of 3-methoxyphenyl, 3-chlorophenyl, and 4-cyanophenyl 4-nitrophenyl thionocarbonates with alicyclic amines.

  The Journal of organic chemistry 20010907

• Monocharged inhibitors of mast cell tryptase derived from potent and selective dibasic inhibitors.

  Bioorganic & medicinal chemistry letters 20010903

• Significance of ligand tails for interaction with the minor groove of B-DNA.

  Biophysical journal 20010901

• Use of gonadotropin-releasing hormone analog with tibolone to prevent cyclic attacks of acute intermittent porphyria.

  Metabolism: clinical and experimental 20010901

• Comparison of practical treatment methods to eradicate pinworm (Dentostomella translucida) infections from Mongolian gerbils (Meroines unguiculatus).

  Contemporary topics in laboratory animal science 20010901

• Continuous beds with vancomycin as chiral stationary phase for capillary electrochromatography.

  Electrophoresis 20010901

• Synthesis and receptor docking studies of N-substituted indole-2-carboxylic acid esters as a search for COX-2 selective enzyme inhibitors.

  European journal of medicinal chemistry 20010901

• Diketopiperazine receptors: a novel class of highly selective receptors for binding small peptides.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010803

• Intracellular PO(2) decreases with increasing stimulation frequency in contracting single Xenopus muscle fibers.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010801

• Prospective evaluation of hot flashes during treatment with parenteral estrogen or complete androgen ablation for metastatic carcinoma of the prostate.

  The Journal of urology 20010801

• Mass spectrometric studies on small open-chain piperazine-containing ligands and their transition metal complexes.

  Journal of mass spectrometry : JMS 20010801

• The discovery of linezolid, the first oxazolidinone antibacterial agent.

  Current drug targets. Infectious disorders 20010801

• Solvent effect on the alpha-effect for the reactions of aryl acetates with butane-2,3-dione monoximate and p-chlorophenoxide in MeCN-H2O mixtures.

  The Journal of organic chemistry 20010713

• Effect of the drug-matrix on the stability of enalapril maleate in tablet formulations.

  Journal of pharmaceutical and biomedical analysis 20010701

• Transcarpal motor conduction velocity in carpal tunnel syndrome.

  Muscle & nerve 20010701

• Effect of reduced dose of triptorelin at the start of ovarian stimulation on the outcome of IVF: a randomized study.

  Human reproduction (Oxford, England) 20010701

• Estrogen 'add-back' and lipid profile during GnRH agonist (triptorelin) therapy.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20010701

• The use of the indicator fluo-5N to measure sarcoplasmic reticulum calcium in single muscle fibres of the cane toad.

  The Journal of physiology 20010701

• The lumbrical provocation test in subjects with median inclusive paresthesia.

  Archives of physical medicine and rehabilitation 20010701

• Chemistry of the diazeniumdiolates. 2. Kinetics and mechanism of dissociation to nitric oxide in aqueous solution.

  Journal of the American Chemical Society 20010613

• Investigations of new lead structures for the design of selective estrogen receptor modulators.

  Journal of medicinal chemistry 20010607

• Determination of the partition coefficients of a homologous series of ciprofloxacin: influence of the N-4 piperazinyl alkylation on the antimicrobial activity.

  International journal of pharmaceutics 20010604

• Isolation and identification of clozapine metabolites in patient urine.

  Drug metabolism and disposition: the biological fate of chemicals 20010601

• Antiproliferative signaling of luteinizing hormone-releasing hormone in human endometrial and ovarian cancer cells through G protein alpha(I)-mediated activation of phosphotyrosine phosphatase.

  Endocrinology 20010601

• Intermolecular and intramolecular Diels-Alder cycloadditions of 3-ylidenepiperazine-2,5-diones and 5-acyloxy-2(1h)-pyrazinones.

  The Journal of organic chemistry 20010601

• Actions of gonadotropin-releasing hormone antagonists on steroidogenesis in human granulosa lutein cells.

  European journal of endocrinology 20010601

• Structural characterization of the oxidative degradation products of an antifungal agent SCH 56592 by LC-NMR and LC-MS.

  Journal of pharmaceutical and biomedical analysis 20010601

• [Study on the latency difference between compound muscle and sensory nerve action potentials].

  No to shinkei = Brain and nerve 20010601

• Leuprorelin and triptorelin: new indication. Preoperative treatment of uterine leiomyoma: no proven value.

  Prescrire international 20010601

• Double-stranded DNA binding characteristics and subcellular distribution of a minor groove binding diphenyl ether bisbenzimidazole.

  Biochemistry 20010529

• Direct effects of GnRH agonists in human hormone-sensitive endometrial cells.

  Molecular and cellular endocrinology 20010515

• Effect of column temperature on the behaviour of some angiotensin converting enzyme inhibitors during high-performance liquid chromatographic analysis.

  Journal of chromatography. B, Biomedical sciences and applications 20010505

• Fall in intracellular PO(2) at the onset of contractions in Xenopus single skeletal muscle fibers.

  Journal of applied physiology (Bethesda, Md. : 1985) 20010501

• Autoregulation of the gonadotropin-releasing hormone (GnRH) system during puberty: effects of antagonistic versus agonistic GnRH analogs in a female rat model.

  The Journal of endocrinology 20010501

• Lumbrical muscle with an additional origin in the forearm.

  ANZ journal of surgery 20010501

• Requirements for the application of protein sodium dodecyl sulfate-polyacrylamide gel electrophoresis and randomly amplified polymorphic DNA analyses to product speciation.

  Electrophoresis 20010501

• Tubular aggregates observed in spindle muscle fiber of horse lumbrical muscle.

  Acta neuropathologica 20010501

• [The results of GnRH analog treatment of endometriosis].

  Ginekologia polska 20010501

• [Decapeptyl (triptorelin) in the treatment of endometriosis genitalis externa].

  Ginekologia polska 20010501

• Dicationic bis(9-methylphenazine-1-carboxamides): relationships between biological activity and linker chain structure for a series of potent topoisomerase targeted anticancer drugs.

  Journal of medicinal chemistry 20010426

• Acrylamide-based monoliths as robust stationary phases for capillary electrochromatography.

  Journal of chromatography. A 20010420

• Comparable clinical outcome using the GnRH antagonist ganirelix or a long protocol of the GnRH agonist triptorelin for the prevention of premature LH surges in women undergoing ovarian stimulation.

  Human reproduction (Oxford, England) 20010401

• Enzyme immunoassay for 6-amino-5-chloro-1-isopropyl-2-(4-methyl-1-piperazinyl)benzimidazole, a novel 5-HT3 receptor antagonist.

  Biological & pharmaceutical bulletin 20010401

• Synthesis and evaluation of radiolabeled piperazine derivatives of vesamicol as SPECT agents for cholinergic neurons.

  Nuclear medicine and biology 20010401

• Factors influencing agonist potency and selectivity for the opioid delta receptor are revealed in structure-activity relationship studies of the 4-[(N-substituted-4-piperidinyl)arylamino]-N,N-diethylbenzamides.

  Journal of medicinal chemistry 20010315

• Improved solid-phase peptide synthesis method utilizing alpha-azide-protected amino acids.

  Organic letters 20010308

• Dose-finding study for the use of long-acting gonadotrophin-releasing hormone analogues prior to ovarian stimulation for IVF.

  Human reproduction (Oxford, England) 20010301

• Anthelmintic activity of the stem bark extracts of Berlina grandiflora and one of its active principles, Betulinic acid.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20010301

• On the branching of motoneurons.

  Muscle & nerve 20010301

• Investigation of solid-state reactions using variable temperature X-ray powder diffractrometry. I. Aspartame hemihydrate.

  Pharmaceutical research 20010301

• [Synthesis and anti-tumor activities of 1,4-bis[3-(amino-dithiocarboxy)propionyl] piperazine derivatives].

  Yao xue xue bao = Acta pharmaceutica Sinica 20010301

• Structure-activity relationships of quinazoline derivatives: dual-acting compounds with inhibitory activities toward both TNF-alpha production and T cell proliferation.

  Bioorganic & medicinal chemistry letters 20010226

• Design of triptorelin loaded nanospheres for transdermal iontophoretic administration.

  International journal of pharmaceutics 20010219

• FK960, a novel potential anti-dementia drug, enhances high K(+)-evoked release of somatostatin from rat hippocampal slices.

  Brain research 20010216

• Ethane-1,2-diphosphonic acid as a building block in supramolecular chemistry; a pillared-layer framework and framework-encapsulated cations.

  Acta crystallographica. Section B, Structural science 20010201

• The dorsal aponeurosis, intrinsic, hypothenar, and thenar musculature of the hand.

  Clinical orthopaedics and related research 20010201

• D-TRP-6-LHRH (Triptorelin) is not effective in ovarian carcinoma: an EORTC Gynaecological Cancer Co-operative Group Study.

  Anti-cancer drugs 20010201

• [Comparison of different protocols of ovulation induction, by GnRH agonists and chorionic gonadotropin].

  Gynecologie, obstetrique & fertilite 20010201

• Endoscopic carpal tunnel release and nerve conduction studies.

  International orthopaedics 20010201

• Synthesis and stereoselective kappa-receptor binding of methylated analogues of GR-89.696.

  European journal of medicinal chemistry 20010201

• Design, synthesis, and modeling of novel cyclic thrombin receptor-derived peptide analogues of the Ser42-Phe-Leu-Leu-Arg46 motif sequence with fixed conformations of pharmacophoric groups: importance of a Phe/Arg/NH2 cluster for receptor activation and implications in the design of nonpeptide thrombin receptor mimetics.

  Journal of medicinal chemistry 20010201

• Asymmetric transformation of N-nitrosamines by inclusion crystallization with optically active hosts.

  The Journal of organic chemistry 20010126

• Liquid-phase parallel synthesis of ureas.

  Bioorganic & medicinal chemistry letters 20010122

• Synthesis and structure-activity relationships of a new model of arylpiperazines. 5. Study of the physicochemical influence of the pharmacophore on 5-HT(1a)/alpha(1)-adrenergic receptor affinity: synthesis of a new derivative with mixed 5-HT(1a)/d(2) antagonist properties.

  Journal of medicinal chemistry 20010118

• N-Terminal peptide aldehydes as electrophiles in combinatorial solid phase synthesis of novel peptide isosteres.

  Journal of combinatorial chemistry 20010101

• Long-term remission of ovarian hyperandrogenism after short-term treatment with a gonadotropin-releasing hormone agonist.

  Fertility and sterility 20010101

• Efficacy of nafarelin in assisted reproductive technology: a meta-analysis.

  Human reproduction update 20010101

• The state of the art of dynamic coatings.

  Electrophoresis 20010101

• Dose-dense sequential adjuvant chemotherapy with epirubicin, paclitaxel and CMF in high-risk breast cancer.

  Oncology 20010101

• Sex hormone replacement therapy reverses decreased venous distensibility in pharmacologically ovariectomized rats.

  Menopause (New York, N.Y.) 20010101

• Investigation of synthetic peptide hormones by liquid chromatography coupled to pneumatically assisted electrospray ionization mass spectrometry: analysis of a synthesis crude of peptide triptorelin.

  Rapid communications in mass spectrometry : RCM 20010101

• [Inactivation of Trypanosoma cruzi trypanothione reductase by phenothiazine cationic free radicals].

  Revista Argentina de microbiologia 20010101

• A practical GnRH analogue (triptorelin) stimulation test to distinguish constitutional delay of puberty from hypogonadotropic hypogonadism in prepubertal boys.

  The Turkish journal of pediatrics 20010101

• [Rugulosuvines A and B--diketopiperazine alkaloids from Penicillium rugulosum and Penicillium piscarium fungi].

  Prikladnaia biokhimiia i mikrobiologiia 20010101

• Functional hyperandrogenism detected by corticotropin and GnRH-analogue stimulation tests in women affected by apparently idiopathic hirsutism.

  Journal of endocrinological investigation 20010101

• Pharmacokinetics and metabolism of a selective PDE5 inhibitor (UK-343,664) in rat and dog.

  Xenobiotica; the fate of foreign compounds in biological systems 20010101

• Gonadotrophin-releasing hormone antagonists for assisted conception.

  The Cochrane database of systematic reviews 20010101

• Solid-phase synthesis of libraries generated from a 4-phenyl-2-carboxy-piperazine scaffold.

  Journal of combinatorial chemistry 20010101

• Return to fertility after extended chemical castration with a GnRH antagonist.

  BMC cancer 20010101

• Biliary Ascariasis in children.

  Journal of Ayub Medical College, Abbottabad : JAMC 20010101

• Antianaphylactic and antiasthmatic properties of new piperazinyl 7-(beta-hydroxypropyl)-theophylline derivatives in guinea pigs.

  Polish journal of pharmacology 20010101

• Synthesis and antibacterial activity of some novel N-substituted piperazinyl-quinolones.

  Bollettino chimico farmaceutico 20010101

• Modulation of angiogenesis and progelatinase a by thrombin receptor mimetics and antagonists.

  Endothelium : journal of endothelial cell research 20010101

• Conversion of nested reverse-transcriptase polymerase chain reaction from positive to negative status at peripheral blood during androgen ablation therapy is associated with long progression-free survival in stage D2 prostate cancer patients.

  Anticancer research 20010101

• Anthelmintics: a review.

  Tropical gastroenterology : official journal of the Digestive Diseases Foundation 20010101

• A phase II trial with new triptorelin sustained release formulations in prostatic carcinoma.

  International urology and nephrology 20010101

• Imipenem-cilastatin-induced leukocytoclastic vasculitis.

  Journal of the American Podiatric Medical Association 19970501

• On the antiarrhythmic activity of one N-substituted piperazine derivative of trans-2-amino-3-hydroxy-1, 2, 3, 4-tetrahydroanaphthalene.

  Acta physiologica et pharmacologica Bulgarica 19790101

• Interaction between piperazine and chlorpromazine.

  British journal of pharmacology 19740101

• [Spasms in simultaneous treatment with piperazine and chlorpromazine].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 19700201