110-99-6 | Diglycolic acid

Packsize	Purity	Availability	Price	Discounted Price
10g	98%	in stock	$12.00	$9.00
25g	98%	in stock	$16.00	$12.00
100g	98%	in stock	$60.00	$42.00

Description

• Catalog Number: AB59658
• Chemical Name: Diglycolic acid
• CAS Number: 110-99-6
• Molecular Formula: C4H6O5
• Molecular Weight: 134.08744
• MDL Number: MFCD00004309
• SMILES: OC(=O)COCC(=O)O
• NSC Number: 8651

Computed Properties

• Complexity: 104
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 4
• XLogP3: -0.7

Literature

• Diglycolic acid inhibits succinate dehydrogenase activity in human proximal tubule cells leading to mitochondrial dysfunction and cell death.

  Toxicology letters 20130829

• Spectroscopic characterization of an oxovanadium(IV) complex of oxodiacetic acid and o-phenanthroline. Bioactivity on osteoblast-like cells in culture.

  Biological trace element research 20120601

• Study on the enzymatic degradation of PBS and its alcohol acid modified copolymer.

  Biodegradation 20120201

• A novel sensor based on electrochemical polymerization of diglycolic acid for determination of acetaminophen.

  Biosensors & bioelectronics 20120101

• Cyto- and genotoxicity of a vanadyl(IV) complex with oxodiacetate in human colon adenocarcinoma (Caco-2) cells: potential use in cancer therapy.

  Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20111201

• Diglycolic acid is the nephrotoxic metabolite in diethylene glycol poisoning inducing necrosis in human proximal tubule cells in vitro.

  Toxicological sciences : an official journal of the Society of Toxicology 20111101

• Role of tissue metabolite accumulation in the renal toxicity of diethylene glycol.

  Toxicological sciences : an official journal of the Society of Toxicology 20111001

• Aqua-bis-(3,5-dimethyl-1H-pyrazole-κN)(oxydiacetato-κO,O',O'')copper(II) dihydrate.

  Acta crystallographica. Section E, Structure reports online 20110601

• Inhibition of metabolism of diethylene glycol prevents target organ toxicity in rats.

  Toxicological sciences : an official journal of the Society of Toxicology 20100901

• Complexation of Np(V) with N,N-dimethyl-3-oxa-glutaramic acid and related ligands: thermodynamics, optical properties and structural aspects.

  Dalton transactions (Cambridge, England : 2003) 20100407

• Hydrogen-bonded network structures in dipyridinium, bis(2-methylpyridinium), bis(3-methylpyridinium) and bis(4-methylpyridinium) dioxidobis(oxydiacetato)uranate(VI).

  Acta crystallographica. Section C, Crystal structure communications 20100315

• Cytotoxicity of a vanadyl(IV) complex with a multidentate oxygen donor in osteoblast cell lines in culture.

  Medicinal chemistry (Shariqah (United Arab Emirates)) 20100101

• Formulation and characterization of patient-friendly dosage form of ondansetron hydrochloride.

  Journal of young pharmacists : JYP 20100101

• Modification of different zirconium propoxide precursors by diethanolamine. Is there a shelf stability issue for sol-gel applications?

  International journal of molecular sciences 20091101

• Diaqua(oxydiacetato-kappa3O,O',O'')(pyridine-3-carboxamide-kappaN1)copper(II).

  Acta crystallographica. Section C, Crystal structure communications 20090801

• 1,3-Bis(1H-benzimidazol-2-yl)-2-oxapropane.

  Acta crystallographica. Section E, Structure reports online 20090501

• 2,3-Dihydro-1,3-benzothiazol-2-iminium hydrogen oxydiacetate: a combined structural and theoretical study.

  Acta crystallographica. Section C, Crystal structure communications 20090101

• Quest for environmentally benign ligands for actinide separations: thermodynamic, spectroscopic, and structural characterization of U(VI) complexes with Oxa-diamide and related ligands.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

• Synthesis and properties of polycarboxylate-type green surfactants with S- or N-linkages.

  Journal of oleo science 20090101

• Redetermination of poly[aquadi-μ(3)-oxy-diacetato-dicopper(II)].

  Acta crystallographica. Section E, Structure reports online 20080101

• Spectroscopic characterization of a VO2+ complex of oxodiacetic acid and its bioactivity on osteoblast-like cells in culture.

  Biological trace element research 20070801

• An ytterbium(II) complex with dimethyl ester of oxydiacetic acid.

  Dalton transactions (Cambridge, England : 2003) 20070714

• Measuring free metal ion concentrations in multicomponent solutions using the Donnan membrane technique.

  Analytical chemistry 20070215

• Synthesis and characterization of the paclitaxel/MPEG-PLA block copolymer conjugate.

  Biomaterials 20050501

• Use of diffusive gradients in thin films to measure cadmium speciation in solutions with synthetic and natural ligands: comparison with model predictions.

  Environmental science & technology 20050115

• A new ether bond-splitting enzyme found in Gram-positive polyethylene glycol 6000-utilizing bacterium, Pseudonocardia sp. strain K1.

  Applied microbiology and biotechnology 20041201

• A systematic evaluation of molecular recognition phenomena. 4. Selective binding of dicarboxylic acids to hexaazamacrocyclic ligands based on molecular flexibility.

  Inorganic chemistry 20040503

• Cloning and expression of an ether-bond-cleaving enzyme involved in the metabolism of polyethylene glycol.

  Journal of bioscience and bioengineering 20040101

• Complexation of uranium(VI) and samarium(III) with oxydiacetic acid: temperature effect and coordination modes.

  Inorganic chemistry 20030602

• Polymeric hexaaquahexakis(mu3-2,2'-oxydiacetato)trizinc(II)digadolinium(III) dodecahydrate.

  Acta crystallographica. Section C, Crystal structure communications 20030501

• Solution chemistry of uranyl ion with iminodiacetate and oxydiacetate: A combined NMR/EXAFS and potentiometry/calorimetry study.

  Inorganic chemistry 20030224

• A new polymeric phase of zinc(II) oxydiacetate.

  Acta crystallographica. Section C, Crystal structure communications 20030101

• Xanthamide fluorescent dyes.

  Analytical chemistry 20021215

• Carboxylate-bridged copper(II)-lanthanide(III) complexes [(Cu(3)Ln(2)(oda)(6)(H(2)O)(6)).12H(2)O](n)(Ln = Dy, Ho, Er, Y; oda = oxydiacetate).

  Inorganic chemistry 20021021

• Synthesis and characterization of uranyl compounds with iminodiacetate and oxydiacetate displaying variable denticity.

  Inorganic chemistry 20020520

• A hydrocarbon anchored peptide that forms a chloride-selective channel in liposomes.

  Chemical communications (Cambridge, England) 20020421

• Microbial degradation of polyethers.

  Applied microbiology and biotechnology 20020101

• Structural studies of lanthanide (III) complexes with oxydiacetic acid and iminodiacetic acid in aqueous solution by EXAFS.

  Journal of synchrotron radiation 20010301

• Zirconium(IV) complexes of oxydiacetic acid in aqueous solution and in the solid state as studied by multinuclear NMR and X-ray crystallography.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20010202