11021-13-9 | Ginsenoside Rb2

Packsize	Purity	Availability	Price	Discounted Price
5mg	98%	in stock	$120.00	$84.00
10mg	98%	in stock	$227.00	$159.00
50mg	98%	in stock	$239.00	$167.00
100mg	98%	in stock	$406.00	$284.00
250mg	98%	in stock	$769.00	$538.00

Description

• Catalog Number: AE08169
• Chemical Name: Ginsenoside Rb2
• CAS Number: 11021-13-9
• Molecular Formula: C53H90O22
• Molecular Weight: 1079.2685
• MDL Number: MFCD00221755
• SMILES: OC[C@H]1O[C@@H](O[C@H]2CC[C@]3([C@H](C2(C)C)CC[C@@]2([C@@H]3C[C@@H](O)[C@H]3[C@@]2(C)CC[C@@H]3[C@@](O[C@@H]2O[C@H](CO[C@@H]3OC[C@@H]([C@@H]([C@H]3O)O)O)[C@H]([C@@H]([C@H]2O)O)O)(CCC=C(C)C)C)C)C)[C@@H]([C@H]([C@@H]1O)O)O[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1O)O)O

Computed Properties

• Complexity: 1950
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 29
• Heavy Atom Count: 75
• Hydrogen Bond Acceptor Count: 22
• Hydrogen Bond Donor Count: 14
• Rotatable Bond Count: 15
• XLogP3: 0.3

Literature

• Effects of ginsenosides on the expression of cytochrome P450s and transporters involved in cholesterol metabolism.

  Journal of natural medicines 20140401

• Enzymatic transformation of the major ginsenoside Rb2 to minor compound Y and compound K by a ginsenoside-hydrolyzing β-glycosidase from Microbacterium esteraromaticum.

  Journal of industrial microbiology & biotechnology 20121001

• Determination of ginsenosides Rb1, Rb2, and Rb3 in rat plasma by a rapid and sensitive liquid chromatography tandem mass spectrometry method: Application in a pharmacokinetic study.

  Journal of pharmaceutical and biomedical analysis 20120501

• Antioxidant, antiproliferative, and pro-apoptotic activities of a saponin extract derived from the roots of Panax notoginseng (Burk.) F.H. Chen.

  Journal of medicinal food 20120401

• AMP-activated protein kinase: a potential target for ginsenosides?

  Archives of pharmacal research 20110701

• The antidiabetic effect of ginsenoside Rb2 via activation of AMPK.

  Archives of pharmacal research 20110701

• [Absorption characteristics of ginsenoside Rb2 in Caco-2 cell monolayer].

  Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20091201

• The ginsenoside-Rb2 lowers cholesterol and triacylglycerol levels in 3T3-L1 adipocytes cultured under high cholesterol or fatty acids conditions.

  BMB reports 20090430

• [A quantitative method using one marker for simultaneous assay of ginsenosides in Panax ginseng and P. notoginseng].

  Yao xue xue bao = Acta pharmaceutica Sinica 20081201

• Method development for gypenosides fingerprint by high performance liquid chromatography with diode-array detection and the addition of internal standard.

  Chemical & pharmaceutical bulletin 20080301

• Study on the noncovalent complexes of ginsenoside and cytochrome c by electrospray ionization mass spectrometry.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071001

• Study on the hydroxyl radical scavenging activity changes of ginseng and ginsenoside-Rb2 by heat processing.

  Biological & pharmaceutical bulletin 20070401

• Purification and characterization of new special ginsenosidase hydrolyzing multi-glycisides of protopanaxadiol ginsenosides, ginsenosidase type I.

  Chemical & pharmaceutical bulletin 20070201

• A ginsenoside metabolite, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol, triggers apoptosis in activated rat hepatic stellate cells via caspase-3 activation.

  Planta medica 20061001

• Transformation of ginsenosides Rb2 and Rc from Panax ginseng by food microorganisms.

  Biological & pharmaceutical bulletin 20051101

• Simultaneous determination of ginsenoside Rb(1) and Rg(1) in human plasma by liquid chromatography-mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20040401

• Enhancement of fibrinolytic activity of bovine aortic endothelial cells by ginsenoside Rb2.

  Acta pharmacologica Sinica 20030201

• Ginsenosides from Panax ginseng differentially regulate lymphocyte proliferation.

  Planta medica 20020601

• Epidermis proliferative effect of the Panax ginseng ginsenoside Rb2.

  Archives of pharmacal research 20020201

• Triterpene saponins from Vietnamese ginseng (Panax vietnamensis) and their hepatocytoprotective activity.

  Journal of natural products 20010401

• In vitro inhibitory effect of protopanaxadiol ginsenosides on tumor necrosis factor (TNF)-alpha production and its modulation by known TNF-alpha antagonists.

  Planta medica 20010401

• Effects of Ginsenoside Rb2 and Rc on inferior human sperm motility in vitro.

  The American journal of Chinese medicine 20010101

• Ginsenosides increase secretion of lipoprotein lipase by 3T3-L1 adipocytes.

  Bioscience, biotechnology, and biochemistry 19961201